phenytoin and adenosine

phenytoin has been researched along with adenosine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's1 (5.26)18.2507
2000's5 (26.32)29.6817
2010's6 (31.58)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bleck, V; Lewin, E1
Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB1
Nelson, JA1
Dryden, EE; Manery, JF; Woo, YT1
Clothier, B; Rundle, AT; Sudell, B1
Anderson, SM; Daly, JW; Padgett, W; Weir, RL1
Phillis, JW1
Borowicz, KK; Czuczwar, SJ; Kleinrok, Z1
Aebischer, P; Boison, D; Déglon, N; Huber, A; Möhler, H; Padrun, V1
Akula, KK; Dhir, A; Kulkarni, SK1
Bogo, MR; Bonan, CD; Nery, LR; Piato, AL; Schaefer, IC; Siebel, AM1
Nathan, S; Raissi, F; Sieg, A; Vahdat, K; Weeks, P1

Reviews

2 review(s) available for phenytoin and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Some clinical and pharmacological applications of high-speed liquid chromatography.
    Advances in chromatography, 1977, Volume: 15

    Topics: Adenosine; Adenosine Deaminase; Animals; Chemistry, Clinical; Chromatography, High Pressure Liquid; Dogs; Enzymes; Erythrocytes; Humans; Hypoxanthines; Inosine; Mustard Compounds; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ribonucleotides

1977

Other Studies

17 other study(ies) available for phenytoin and adenosine

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Cyclic AMP accumulation in cerebral cortical slices: effect of carbamazepine, phenobarbital, and phenytoin.
    Epilepsia, 1977, Volume: 18, Issue:2

    Topics: Adenosine; Animals; Brain Chemistry; Carbamazepine; Cyclic AMP; Female; In Vitro Techniques; Norepinephrine; Ouabain; Phenobarbital; Phenytoin; Rats

1977
Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain.
    Epilepsia, 1979, Volume: 20, Issue:2

    Topics: Adenosine; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebellum; Cerebral Cortex; Clonazepam; Culture Techniques; Cyclic AMP; Diazepam; Male; Mice; Norepinephrine; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Premedication; Seizures

1979
Theophylline inhibition of nucleoside transport and its relation to cyclic AMP in skeletal muscle.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:6

    Topics: Adenine; Adenosine; Animals; Biological Transport; Bucladesine; Caffeine; Carbon Radioisotopes; Chromatography, Paper; Cyclic AMP; Hypoxanthines; In Vitro Techniques; Inosine; Isoproterenol; Muscle Contraction; Muscles; Nucleosides; Phenytoin; Propranolol; Protein Binding; Purines; Rana pipiens; Ribose; Sorbitol; Theophylline; Tritium; Uridine

1974
Haptoglobin phenotype frequencies in mentally retarded persons.
    Clinical chemistry, 1972, Volume: 18, Issue:11

    Topics: Acid Phosphatase; Adenine Nucleotides; Adenosine; Alanine Transaminase; Aminohydrolases; Blood Protein Electrophoresis; Blood Proteins; Electrophoresis, Starch Gel; Female; Haptoglobins; Humans; Immunodiffusion; Intellectual Disability; Isoenzymes; L-Lactate Dehydrogenase; Liver Function Tests; Male; Phenotype; Phenytoin; Phosphoglucomutase; Phosphogluconate Dehydrogenase; Phosphotransferases; Primidone

1972
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
    Epilepsia, 1984, Volume: 25, Issue:4

    Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1984
Interactions of the anticonvulsants diphenylhydantoin and carbamazepine with adenosine on cerebral cortical neurons.
    Epilepsia, 1984, Volume: 25, Issue:6

    Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Male; Neurons; Phenytoin; Rats; Rats, Inbred Strains

1984
N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.
    European journal of pharmacology, 1997, May-30, Volume: 327, Issue:2-3

    Topics: Adenosine; Animals; Anticonvulsants; Body Temperature; Carbamazepine; Darkness; Drug Synergism; Electroshock; Female; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Purinergic P1 Receptor Agonists; Valproic Acid

1997
Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jun-19, Volume: 98, Issue:13

    Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Aggression; Animals; Brain; Cell Line; Cell Transplantation; Cricetinae; Epilepsies, Partial; Exploratory Behavior; Fibroblasts; Genetic Therapy; Kindling, Neurologic; Male; Mice; Mice, Knockout; Motor Activity; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Social Behavior; Xanthines

2001
Effect of various antiepileptic drugs in a pentylenetetrazol-induced seizure model in mice.
    Methods and findings in experimental and clinical pharmacology, 2009, Volume: 31, Issue:7

    Topics: Adenosine; Algorithms; Animals; Anti-Inflammatory Agents; Anticonvulsants; Barbiturates; Carbamazepine; Central Nervous System Depressants; Convulsants; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Ethanol; Infusions, Intravenous; Lactones; Male; Mice; Pentylenetetrazole; Phenytoin; Plant Extracts; Seizures; Sulfones; Withania

2009
Antiepileptic drugs prevent changes in adenosine deamination during acute seizure episodes in adult zebrafish.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 104

    Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase; Amines; Animals; Anticonvulsants; Brain; Cyclohexanecarboxylic Acids; Disease Models, Animal; Female; Gabapentin; gamma-Aminobutyric Acid; Gene Expression; Male; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid; Zebrafish

2013
Improved ticagrelor antiplatelet effect on discontinuation of phenytoin.
    The Annals of pharmacotherapy, 2014, Volume: 48, Issue:5

    Topics: Adenosine; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Male; Middle Aged; Percutaneous Coronary Intervention; Phenytoin; Platelet Aggregation Inhibitors; Ticagrelor

2014