phenytoin and acetaminophen

phenytoin has been researched along with acetaminophen in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (40.00)	18.7374
1990's	7 (10.00)	18.2507
2000's	18 (25.71)	29.6817
2010's	15 (21.43)	24.3611
2020's	2 (2.86)	2.80

Authors

Authors	Studies
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Akamatsu, M	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A	1
Harner, RS; McDowell, AE; Pardue, HL	1
Richens, A	1
Perucca, E; Richens, A	1
Frisch, S; Scanlan, M	1
Fleisher, D; Lu, HH; Thomas, JD; Tukker, JJ	1
Blair, TL; Callender, ME; Hyland, M; McClements, BM	1
Bock, KW; Bock-Hennig, BS	1
D'Ver, AS; Ecobichon, DJ; Ehrhart, W	1
Frankel, RJ; Henry, JA; Minton, NA	1
Bircher, J; Blume, R; Bock, KW; Ullrich, D; Wiltfang, J	1
Atiyeh, M; Chaleby, K; el-Yazigi, A	1
Dolara, P; Lodovici, M; Muscas, GC; Salvadori, M; Zaccara, G	1
Gupta, RN; Wright, N	1
Lum, JT; Wells, PG	1
Opheim, KE; Raisys, VA	1
Gallanosa, AG; Spyker, DA	1
Jatlow, P	1
Ganshorn, A; Kurz, H	1
Röttger, HJ; Windorfer, A	1
Ballinger, BR; Simpson, E; Stewart, MJ	1
Nuss, GW; Risley, EA; Van Arman, CG	1
Trautmann, A	1
Flessa, HC; Sigell, LT	1
Meloff, K	1
Guillory, JK; Hwang, SC; Lach, JL	1
Greene, W	1
Wells, PG	1
D'Arcy, PF	1
Goldberg, DM	1
Cunningham, JL; Evans, DA	1
Anderson, PJ; Critchley, JA; Kay, R; Ng, MC; Tomlinson, B; Young, RP	1
Abbott, FS; Farrell, K; Tabatabaei, AR; Thies, RL	1
Grant, DJ; Zhang, GG	1
Bloch, JD; Brackett, CC	1
Rumack, BH	2
Bi, K; Dai, R; Luo, X; Wang, X	1
Heath, DA; Wilding, P	1
Aboo, A; Adams, BK; Evans, A; Isaacs, S; Mann, MD	1
Kostrubsky, SE; Kulkarni, S; Mutlib, A; Sinclair, JF; Stolz, DB; Strom, SC; Urda, E; Wen, YH; Wood, S	1
Facciuto, M; Kim-Schluger, L; Lebovics, E; Lee, Y; Marvin, MR; Ramaswamy, G; Sheiner, PA; Suchin, SM; Wolf, DC	1
Clark, RF; Cook, MD; Williams, SR	1
Budha, NR; Christensen, ML; Mehrotra, N; Meibohm, B; Zhang, Y	1
Lin, B; Ma, B; Qin, J; Zhang, G	1
Hantson, P; Wittebole, X	1
Šakić, D; Šonjić, P; Tandarić, T; Vrček, V	1
Gaohua, L; Jamei, M; Johnson, TN; Neuhoff, S; Rostami-Hodjegan, A	1
Beukers, MW; Danhof, M; de Lange, ECM; Huntjens, DR; Kokki, H; Kokki, M; Krauwinkel, W; Proost, JH; Välitalo, PA; van Hasselt, JGC; Vermeulen, A; Wong, YC; Yamamoto, Y	1
Carter, J; Daughtry, S; Garza, KY; Jarrar, P; Knezevic, CE; Mahomes, A; Martin, J; Mercer, A	1

Reviews

9 review(s) available for phenytoin and acetaminophen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Interactions with antiepileptic drugs. Drugs, 1977, Volume: 13, Issue:4 Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D	1977
Therapeutic drug monitoring in pediatric acute drug intoxications. Therapeutic drug monitoring, 1985, Volume: 7, Issue:2 Topics: Acetaminophen; Alcoholic Intoxication; Antidepressive Agents, Tricyclic; Child; Humans; Iron; Kinetics; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Poisoning; Salicylates; Salicylic Acid; Theophylline	1985
Sulindac hepatotoxicity: a case report and review. Journal of toxicology. Clinical toxicology, 1985, Volume: 23, Issue:2-3 Topics: Acetaminophen; Adolescent; Adult; Aged; Animals; Child; Drug Interactions; Enzyme Induction; Ethanol; Female; Humans; Indenes; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Propionates; Sulindac	1985
Drug interactions involving cimetidine--mechanisms, documentation, implications. Quarterly reviews on drug metabolism and drug interactions, 1984, Volume: 5, Issue:1 Topics: Acetaminophen; Adrenergic beta-Antagonists; Analgesics, Opioid; Animals; Antacids; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antifungal Agents; Aspirin; Benzodiazepines; Cimetidine; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Iron; Lidocaine; Pancreas; Phenytoin; Prednisolone; Theophylline; Vitamin B 12	1984
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry. Clinical chemistry, 1980, Volume: 26, Issue:6 Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin	1980
Acetaminophen misconceptions. Hepatology (Baltimore, Md.), 2004, Volume: 40, Issue:1 Topics: Acetaminophen; Alcohol Drinking; Analgesics, Non-Narcotic; Drug Interactions; Humans; Liver; Phenobarbital; Phenytoin	2004
Potentiation of acetaminophen hepatotoxicity by phenytoin, leading to liver transplantation. Digestive diseases and sciences, 2005, Volume: 50, Issue:10 Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anticonvulsants; Drug Synergism; Humans; Liver Failure, Acute; Liver Transplantation; Male; Phenytoin	2005
Use of the molecular adsorbent recirculating system (MARS™) for the management of acute poisoning with or without liver failure. Clinical toxicology (Philadelphia, Pa.), 2011, Volume: 49, Issue:9 Topics: Acetaminophen; Acute Disease; Albumins; Amanita; Amphetamine; Calcium Channel Blockers; Cocaine; Heavy Metal Poisoning; Humans; Lamotrigine; Liver Failure; Liver, Artificial; Metals, Heavy; Mushroom Poisoning; Phenytoin; Poisoning; Sorption Detoxification; Triazines	2011

Trials

1 trial(s) available for phenytoin and acetaminophen

Article	Year
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs. British journal of clinical pharmacology, 1979, Volume: 7, Issue:2 Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone	1979

Other Studies

60 other study(ies) available for phenytoin and acetaminophen

Article	Year
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
QSAR study on permeability of hydrophobic compounds with artificial membranes. Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11 Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Importance of physicochemical properties for the design of new pesticides. Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7 Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity. Bioorganic & medicinal chemistry letters, 2021, 10-01, Volume: 49 Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines	2021
Application of a vidicon spectrometer for simultaneous multicomponent drug determinations. Clinical chemistry, 1976, Volume: 22, Issue:11 Topics: Acetaminophen; Aminophylline; Barbiturates; Computers; Humans; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phenytoin; Procainamide; Regression Analysis; Salicylamides; Secobarbital; Spectrophotometry, Ultraviolet; Time Factors	1976
Nasoduodenal feeding tubes: prevention of occlusion. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses, 1992, Volume: 24, Issue:5 Topics: Acetaminophen; Dexamethasone; Dosage Forms; Enteral Nutrition; Humans; Intubation, Gastrointestinal; Phenytoin; Therapeutic Irrigation; Trimethoprim, Sulfamethoxazole Drug Combination	1992
Intestinal water and solute absorption studies: comparison of in situ perfusion with chronic isolated loops in rats. Pharmaceutical research, 1992, Volume: 9, Issue:7 Topics: Acetaminophen; Animals; Buffers; Cell Membrane Permeability; Glucose; Intestinal Absorption; Jejunum; Male; Perfusion; Phenytoin; Rats; Rats, Sprague-Dawley; Solutions; Water	1992
Management of paracetamol poisoning complicated by enzyme induction due to alcohol or drugs. Lancet (London, England), 1990, Jun-23, Volume: 335, Issue:8704 Topics: Acetaminophen; Adolescent; Adult; Alcohol Drinking; Aspartate Aminotransferases; Humans; Liver; Male; Phenytoin; Poisoning; Renal Dialysis	1990
Differential induction of human liver UDP-glucuronosyltransferase activities by phenobarbital-type inducers. Biochemical pharmacology, 1987, Dec-01, Volume: 36, Issue:23 Topics: Acetaminophen; Adolescent; Adult; Benzopyrenes; Bilirubin; Carcinoma, Hepatocellular; Enzyme Induction; Female; Glucuronosyltransferase; Humans; Hydroquinones; Hymecromone; Isoenzymes; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; Middle Aged; Naphthols; Pentobarbital; Phenytoin; Tumor Cells, Cultured	1987
Drug disposition and biotransformation in the developing beagle dog. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1988, Volume: 11, Issue:1 Topics: Acetaminophen; Aging; Animals; Biotransformation; Blood Proteins; Dogs; Female; Half-Life; Male; Pharmacokinetics; Phenobarbital; Phenytoin; Protein Binding; Ultrafiltration	1988
Fatal paracetamol poisoning in an epileptic. Human toxicology, 1988, Volume: 7, Issue:1 Topics: Acetaminophen; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Clobazam; Cytochrome P-450 Enzyme System; Drug Interactions; Epilepsy; Humans; Liver; Male; Phenytoin; Primidone	1988
Paracetamol as a test drug to determine glucuronide formation in man. Effects of inducers and of smoking. European journal of clinical pharmacology, 1987, Volume: 31, Issue:6 Topics: Acetaminophen; Adult; Chromatography, High Pressure Liquid; Female; Glucuronates; Humans; Hydrocortisone; Kinetics; Male; Middle Aged; Phenytoin; Rifampin; Smoking; Spectrophotometry, Ultraviolet	1987
Decreased drug absorption in a patient with Behçet's syndrome. Clinical chemistry, 1987, Volume: 33, Issue:9 Topics: Acetaminophen; Adult; Amitriptyline; Behcet Syndrome; Biological Availability; Diazepam; Female; Humans; Inflammation; Intestinal Diseases; Kinetics; Malabsorption Syndromes; Phenytoin	1987
Urinary 6-beta-OH-cortisol and paracetamol metabolites as a probe for assessing oxidation and conjugation of chemicals in humans. Pharmacological research communications, 1987, Volume: 19, Issue:4 Topics: Acetaminophen; Acetyltransferases; Adolescent; Adult; Aged; Chromatography, High Pressure Liquid; Glucuronates; Humans; Hydrocortisone; Hydroxylation; Male; Middle Aged; Oxidation-Reduction; Pharmacokinetics; Phenytoin; Sulfates	1987
The role of the laboratory in acute poisoning: case histories. Clinical biochemistry, 1986, Volume: 19, Issue:2 Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Amitriptyline; Ethylene Glycols; Female; Hemoperfusion; Humans; Male; Phenytoin; Poisoning; Renal Dialysis; Suicide, Attempted	1986
Pharmacological studies on the potentiation of phenytoin teratogenicity by acetaminophen. Teratology, 1986, Volume: 33, Issue:1 Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Brain; Cleft Palate; Drug Synergism; Embryo Loss; Female; Housing, Animal; Liver; Metabolic Clearance Rate; Mice; Phenytoin; Placenta; Pregnancy; Teratogens	1986
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences. American journal of clinical pathology, 1973, Volume: 59, Issue:2 Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin	1973
[Differences between the protein binding of newborns and adults and their importance for pharmacological action]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2 Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental	1968
[Micro-method for the quantitative determination of sedatives and antipyretics (aminophenazone, diphenylhydantoin, paracetamol, phenobarbital, primidone) using thermo-gas chromatography]. Arzneimittel-Forschung, 1974, Volume: 24, Issue:6 Topics: Acetaminophen; Aminopyrine; Analgesics; Chromatography, Gas; Hypnotics and Sedatives; Methods; Microchemistry; Phenobarbital; Phenytoin; Primidone; Temperature	1974
An evaluation of a drug administration system in a psychiatric hospital. The British journal of psychiatry : the journal of mental science, 1974, Volume: 125, Issue:0 Topics: Acetaminophen; Antidepressive Agents; Benzodiazepinones; Hospitals, Psychiatric; Humans; Medication Errors; Medication Systems, Hospital; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Salicylates; Scotland	1974
Interactions of aspirin, indomethacin and other drugs in adjuvant-induced arthritis in the rat. The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:2 Topics: Acetaminophen; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Body Weight; Chlorpromazine; Cyclophosphamide; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Hydrocortisone; Indomethacin; Male; Mycobacterium; Phenytoin; Prednisolone; Rats; Salicylates; Spironolactone; Time Factors	1973
[Dialysis of drugs and poisons. 2]. Medizinische Klinik, 1972, Nov-03, Volume: 67, Issue:44 Topics: Acetaminophen; Aminopyrine; Amitriptyline; Aspirin; Carbamazepine; Chlordiazepoxide; Chlorpromazine; Dextropropoxyphene; Diazepam; Heroin; Humans; Imipramine; Lithium; Pargyline; Pentazocine; Phenacetin; Phenelzine; Phenytoin; Poisoning; Primidone; Promazine; Renal Dialysis; Salicylates; Tranylcypromine; Trifluoperazine	1972
Drug interactions with anticoagulants. JAMA, 1970, Dec-14, Volume: 214, Issue:11 Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Anticoagulants; Ascorbic Acid; Barbiturates; Blood Coagulation; Blood Coagulation Tests; Cardiac Glycosides; Chlordiazepoxide; Chlorothiazide; Contraceptives, Oral; Diazepam; Dogs; Drug Antagonism; Epinephrine; Ethchlorvynol; Glucagon; Haloperidol; Humans; Methylphenidate; Phenethylamines; Phenylbutazone; Phenytoin; Quinolines; Salicylates; Steroids; Substance-Related Disorders; Tetanus Toxoid; Tolbutamide; Xanthines	1970
Seizures and fever. Postgraduate medicine, 1971, Volume: 50, Issue:1 Topics: Acetaminophen; Acidosis, Respiratory; Age Factors; Alkalosis, Respiratory; Aspirin; Brain Diseases; Child, Preschool; Electroencephalography; Fever; Gastrointestinal Diseases; Humans; Hyponatremia; Infant; Phenobarbital; Phenytoin; Prognosis; Respiratory Tract Infections; Seizures; Syncope	1971
Interactions between pharmaceutical compounds by thermal methods. Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:3 Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K	1969
Physiological and environmental determinants of phenytoin teratogenicity: relation to glutathione homeostasis, and potentiation by acetaminophen. Progress in clinical and biological research, 1983, Volume: 135 Topics: Acetaminophen; Acetylcysteine; Animals; Cleft Palate; Drug Synergism; Female; Fetal Resorption; Glutathione; Homeostasis; Mice; Phenytoin; Pregnancy; Teratogens; Time Factors	1983
Early reports on drug interactions. Drug intelligence & clinical pharmacy, 1983, Volume: 17, Issue:2 Topics: Acetaminophen; Amiodarone; Apazone; Aspirin; Carbamazepine; Chlordiazepoxide; Cimetidine; Coumarins; Drug Interactions; Erythromycin; Ethanol; Furosemide; Gentamicins; Humans; Levodopa; Lidocaine; Phenytoin; Prenylamine; Quinidine	1983
Acetanilide and paracetamol pharmacokinetics before and during phenytoin administration: genetic control of induction? British journal of clinical pharmacology, 1981, Volume: 11, Issue:6 Topics: Acetaminophen; Acetanilides; Adult; Enzyme Induction; Humans; Kinetics; Male; Molecular Biology; Phenytoin	1981
Selective liver enzyme induction by carbamazepine and phenytoin in Chinese epileptics. European journal of clinical pharmacology, 1996, Volume: 50, Issue:5 Topics: Acetaminophen; Adult; Anticonvulsants; Carbamazepine; China; Cytochrome P-450 Enzyme System; Enzyme Induction; Epilepsy, Tonic-Clonic; Female; Glucuronates; Humans; Hydrocortisone; Liver; Male; Phenytoin	1996
A rapid in vitro assay for evaluation of metabolism-dependent cytotoxicity of antiepileptic drugs on isolated human lymphocytes. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1997, Volume: 37, Issue:2 Topics: Acetaminophen; Animals; Anticonvulsants; Biological Assay; Carbamazepine; Cell Count; Cell Survival; Female; Fluorescence; Humans; In Vitro Techniques; Lymphocytes; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits	1997
Incorporation mechanism of guest molecules in crystals: solid solution or inclusion? International journal of pharmaceutics, 1999, Apr-20, Volume: 181, Issue:1 Topics: Acetaminophen; Adipates; Caprylates; Crystallization; Kinetics; Oleic Acid; Phenytoin; Solutions; Water	1999
Phenytoin as a possible cause of acetaminophen hepatotoxicity: case report and review of the literature. Pharmacotherapy, 2000, Volume: 20, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Female; Humans; Liver Function Tests; Lung Diseases, Obstructive; Middle Aged; Mixed Function Oxygenases; Phenytoin; Seizures; Venous Thrombosis	2000
Acetaminophen hepatotoxicity: the first 35 years. Journal of toxicology. Clinical toxicology, 2002, Volume: 40, Issue:1 Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Anticonvulsants; Aspartate Aminotransferases; Barbiturates; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Drug Therapy, Combination; Enzyme Induction; Ethanol; Humans; Liver; Liver Diseases; Nutritional Physiological Phenomena; Phenytoin	2002
[Application of statistical simulation spectrophotometry to the determination of four medicaments in feibaosanxiao tablets]. Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:9 Topics: Acetaminophen; Caffeine; Drug Combinations; Monte Carlo Method; Phenytoin; Spectrophotometry; Tablets; Theophylline	1998
Effect of paracetamol on uric acid determination. Annals of clinical biochemistry, 1975, Volume: 12, Issue:4 Topics: Acetaminophen; Adult; Anticonvulsants; Autoanalysis; Bromides; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Drug Overdose; False Positive Reactions; Female; Humans; Oxidation-Reduction; Phenobarbital; Phenytoin; Phosphotungstic Acid; Severity of Illness Index; Substance-Related Disorders; Time Factors; Urate Oxidase; Uric Acid	1975
Prolonged gastric emptying half-time and gastric hypomotility after drug overdose. The American journal of emergency medicine, 2004, Volume: 22, Issue:7 Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Central Nervous System Agents; Colloids; Drug Overdose; Female; Follow-Up Studies; Gastric Emptying; Gastrointestinal Motility; Humans; Male; Middle Aged; Phenytoin; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Stomach; Technetium Compounds; Tin Compounds	2004
Phenobarbital and phenytoin increased acetaminophen hepatotoxicity due to inhibition of UDP-glucuronosyltransferases in cultured human hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology, 2005, Volume: 87, Issue:1 Topics: Acetaminophen; Cells, Cultured; Drug Interactions; Glucuronides; Glucuronosyltransferase; Glutathione; Hepatocytes; Humans; Liver; Phenobarbital; Phenytoin	2005
Phenytoin-potentiated hepatotoxicity following acetaminophen overdose? A closer look. Digestive diseases and sciences, 2007, Volume: 52, Issue:1 Topics: Acetaminophen; Analgesics, Non-Narcotic; Anticonvulsants; Drug Overdose; Drug Synergism; Humans; Liver Failure, Acute; Phenytoin	2007
A tandem mass spectrometry assay for the simultaneous determination of acetaminophen, caffeine, phenytoin, ranitidine, and theophylline in small volume pediatric plasma specimens. Clinica chimica acta; international journal of clinical chemistry, 2008, Volume: 398, Issue:1-2 Topics: Acetaminophen; Analgesics; Anticonvulsants; Bronchodilator Agents; Caffeine; Calibration; Central Nervous System Stimulants; Chromatography, High Pressure Liquid; Histamine H2 Antagonists; Humans; Infant, Newborn; Phenytoin; Quality Control; Ranitidine; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Theophylline	2008
Characterization of drug metabolites and cytotoxicity assay simultaneously using an integrated microfluidic device. Lab on a chip, 2009, Jan-21, Volume: 9, Issue:2 Topics: Acetaminophen; Cell Line; Dimethylpolysiloxanes; Glucuronosyltransferase; Humans; Microfluidic Analytical Techniques; Phenytoin; Toxicity Tests; Uridine Diphosphate Glucuronic Acid	2009
Chlorination of N-methylacetamide and amide-containing pharmaceuticals. Quantum-chemical study of the reaction mechanism. The journal of physical chemistry. A, 2014, Mar-27, Volume: 118, Issue:12 Topics: Acetamides; Acetaminophen; Amides; Carbamazepine; Chemistry, Pharmaceutical; Chlorine; Computer Simulation; Halogenation; Models, Chemical; Molecular Structure; Phenytoin; Quantum Theory; Solvents; Water	2014
Development of a permeability-limited model of the human brain and cerebrospinal fluid (CSF) to integrate known physiological and biological knowledge: Estimating time varying CSF drug concentrations and their variability using in vitro data. Drug metabolism and pharmacokinetics, 2016, Volume: 31, Issue:3 Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adolescent; Adult; Blood-Brain Barrier; Brain; Humans; Male; Middle Aged; Models, Neurological; Phenytoin; Young Adult	2016
Prediction of human CNS pharmacokinetics using a physiologically-based pharmacokinetic modeling approach. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2018, Jan-15, Volume: 112 Topics: Acetaminophen; Animals; Biological Transport; Brain; Brain Injuries, Traumatic; Central Nervous System Agents; Epilepsy; Humans; Models, Biological; Morphine; Oxycodone; Phenytoin; Rats	2018
Evaluation of serum and rapid serum separator collection tubes for therapeutic drug assays. Clinical biochemistry, 2023, Volume: 115 Topics: Acetaminophen; Amikacin; Benzodiazepines; Biological Assay; Humans; Phenytoin	2023