Compounds > phenytoin

phenytoin and 4-hydroxymephenytoin

phenytoin has been researched along with 4-hydroxymephenytoin in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Desiderio, C; Fanali, S; Küpfer, A; Thormann, W1
Bajpai, M; Levy, RH; Roskos, LK; Shen, DD1
Kalhorn, TF; Lakehal, F; Levy, RH; Wurden, CJ1

Other Studies

3 other study(ies) available for phenytoin and 4-hydroxymephenytoin

ArticleYear
Analysis of mephenytoin, 4-hydroxymephenytoin and 4-hydroxyphenytoin enantiomers in human urine by cyclodextrin micellar electrokinetic capillary chromatography: simple determination of a hydroxylation polymorphism in man.
    Electrophoresis, 1994, Volume: 15, Issue:1

    Topics: Buffers; Capillary Action; Chromatography; Cyclodextrins; Humans; Hydroxylation; Kinetics; Mephenytoin; Micelles; Phenytoin; Stereoisomerism

1994
Roles of cytochrome P4502C9 and cytochrome P4502C19 in the stereoselective metabolism of phenytoin to its major metabolite.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:12

    Topics: Aryl Hydrocarbon Hydroxylases; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2C19; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Kinetics; Mephenytoin; Microsomes, Liver; Mixed Function Oxygenases; Phenytoin; Stereoisomerism; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

1996
Carbamazepine and oxcarbazepine decrease phenytoin metabolism through inhibition of CYP2C19.
    Epilepsy research, 2002, Volume: 52, Issue:2

    Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Chlorophyll; Cytochrome P-450 CYP2C19; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Liver; Mephenytoin; Microsomes; Mixed Function Oxygenases; Oxcarbazepine; Phenytoin; Recombinant Proteins

2002