Page last updated: 2024-08-18

phenylpiperazine and lassbio-579

phenylpiperazine has been researched along with lassbio-579 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barreiro, EJ; Betti, AH; Conrado, DJ; Fraga, CA; Kliemann, M; Neves, G; Rates, SM; Tasso, L1
Antonio, CB; Barreiro, EJ; Fraga, CA; Grazziottin, LR; Menegatti, R; Neves, G; Noël, F; Rates, SM; Vieira, RO1
Andrade, CH; Antonio, CB; Barreiro, EJ; Betti, AH; Dalla Costa, T; de Oliveira, V; Fraga, CA; Gil, ES; Gomes, TF; Menegatti, R; Noël, F; Pompeu, TE; Rates, SM; Rodrigues, DA; Sabino, JR1
Alves, FR; Antonio, CB; Barreiro, EJ; Figueiredo, CD; Fraga, CA; Herzfeldt, V; Moura, BC; Noël, F; Pompeu, TE; Rates, SM1

Other Studies

4 other study(ies) available for phenylpiperazine and lassbio-579

ArticleYear
Serotonergic neurotransmission mediates hypothermia induced by the N-phenylpiperazine antipsychotic prototypes LASSBio-579 and LASSBio-581.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 89, Issue:1

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Body Temperature; Haloperidol; Hypothermia; Injections, Intraperitoneal; Male; Mice; Piperazines; Pyridines; Serotonin; Serotonin Antagonists; Synaptic Transmission

2008
Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors.
    Bioorganic & medicinal chemistry, 2010, Mar-01, Volume: 18, Issue:5

    Topics: Administration, Oral; Animals; Antipsychotic Agents; Cell Line; Humans; Ligands; Male; Mice; Piperazines; Pyrazoles; Rats; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Schizophrenia

2010
Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Animals; Antipsychotic Agents; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Lead; Male; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Organometallic Compounds; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine D4; Structure-Activity Relationship

2013
Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579.
    European journal of medicinal chemistry, 2013, Volume: 66

    Topics: Animals; Antipsychotic Agents; Behavior, Animal; Chemistry Techniques, Synthetic; Dose-Response Relationship, Drug; Drug Design; Locomotion; Male; Mice; Piperazines; Receptor, Serotonin, 5-HT2A; Schizophrenia

2013