phenylmorphan has been researched along with morphinans in 16 studies
| Studies (phenylmorphan) | Trials (phenylmorphan) | Recent Studies (post-2010) (phenylmorphan) | Studies (morphinans) | Trials (morphinans) | Recent Studies (post-2010) (morphinans) |
|---|---|---|---|---|---|
| 17 | 0 | 10 | 3,251 | 307 | 648 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| Froimowitz, M; Pasternak, GW; Pick, CG | 1 |
| Froimowitz, M | 1 |
| Deschamps, JR; Flippen-Anderson, JL; Gu, XH; Jacobson, AE; Kodato, S; Linders, JT; Rice, KC; Yamada, K | 1 |
| Dersch, CM; Jacobson, AE; Kim, IJ; Rice, KC; Rothman, RB | 1 |
| Deschamps, JR; Flippen-Anderson, JL; George, C; Hashimoto, A; Jacobson, AE; Kodato, S; Linders, JT; Przybyl, AK; Rice, KC; Tian, X | 1 |
| Dersch, CM; Deschamps, J; Hashimoto, A; Jacobson, AE; Lee, YS; Przybył, AK; Rice, KC; Rothman, RB; Singer, L; Zezula, J | 1 |
| Dersch, CM; Deschamps, JR; Jacobson, AE; Lee, YS; Rice, KC; Rothman, RB; Zhang, Y | 1 |
| Cheng, K; Dersch, CM; Deschamps, JR; Folk, JE; Jacobson, AE; Kim, JH; Rice, KC; Rothman, RB | 1 |
| Cheng, K; Deck, JA; Dersch, CM; Deschamps, JR; Folk, JE; Jacobson, AE; Kurimura, M; Li, F; Rice, KC; Rothman, RB | 1 |
| Deschamps, JR; Jacobson, AE; Lim, HJ; Rice, KC | 1 |
| Dersch, CM; Deschamps, JR; Iyer, MR; Jacobson, AE; Lee, YS; Rice, KC; Rothman, RB | 1 |
| Deck, JA; Dersch, CM; Deschamps, JR; Jacobson, AE; Li, F; Rice, KC; Rothman, RB | 1 |
| Dersch, CM; Deschamps, JR; Jacobson, AE; Lim, HJ; Rice, KC; Rothman, RB | 1 |
| Deschamps, JR; Imler, GH; Jacobson, AE; Katz, JL; Kopajtic, TA; Li, F; Luo, D; Prisinzano, TE; Rice, KC | 1 |
| Bergman, J; Bow, EW; Gutman, ES; Imler, GH; Jacobson, AE; Kaska, S; Kerr, AT; Luo, D; Lutz, JA; Paronis, CA; Prisinzano, TE; Rice, KC; Sulima, A | 1 |
| Chambers, DR; Jacobson, AE; Luo, D; Prisinzano, TE; Rice, KC; Sulima, A | 1 |
16 other study(ies) available for phenylmorphan and morphinans
| Article | Year |
|---|---|
Phenylmorphans and analogues: opioid receptor subtype selectivity and effect of conformation on activity.
Topics: Analgesics; Animals; Male; Mice; Molecular Conformation; Morphinans; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship; Substrate Specificity | 1992 |
Preferred conformers for the pharmacologically typical and atypical antipodes of phenylmorphan opiates.
Topics: Molecular Conformation; Morphinans; Morphine; Stereoisomerism; Structure-Activity Relationship; X-Ray Diffraction | 1984 |
Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para-f oxide-bridged phenylmorphan isomers.
Topics: Benzofurans; Crystallography, X-Ray; Isomerism; Molecular Conformation; Molecular Structure; Morphinans; Oxides; Pyridines | 2004 |
A critical structural determinant of opioid receptor interaction with phenolic 5-phenylmorphans.
Topics: Animals; Ligands; Morphinans; Phenols; Receptors, Opioid | 2004 |
Probes for narcotic receptor-mediated phenomena. 33. Construction of a strained trans-5,6-ring system by displacement of a nitro-activated aromatic fluorine. synthesis of the penultimate oxide-bridged phenylmorphans.
Topics: Bridged-Ring Compounds; Crystallography, X-Ray; Fluorine; Molecular Probes; Molecular Structure; Morphinans; Receptors, Opioid; Stereoisomerism | 2004 |
Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Haplorhini; Mice; Models, Chemical; Molecular Structure; Morphinans; Narcotic Antagonists; Oxygen; Phenylethyl Alcohol; Quantum Theory; Stereoisomerism | 2008 |
Probes for narcotic receptor mediated phenomena. 39. Enantiomeric N-substituted benzofuro[2,3-c]pyridin-6-ols: synthesis and topological relationship to oxide-bridged phenylmorphans.
Topics: Animals; CHO Cells; Cricetinae; Cricetulus; Humans; Models, Molecular; Molecular Conformation; Morphinans; Nitrogen; Oxides; Pyridines; Quantum Theory; Receptors, Opioid; Stereoisomerism | 2009 |
Probes for narcotic receptor mediated phenomena. Part 42: synthesis and in vitro pharmacological characterization of the N-methyl and N-phenethyl analogues of the racemic ortho-c and para-c oxide-bridged phenylmorphans.
Topics: Crystallography, X-Ray; Molecular Conformation; Morphinans; Narcotic Antagonists; Oxides; Protein Binding; Receptors, Opioid; Stereoisomerism | 2011 |
Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Conformation; Morphinans; Narcotic Antagonists; Oxides; Stereoisomerism; Structure-Activity Relationship | 2011 |
Diastereoselective one-pot synthesis of 7- and 8-substituted 5-phenylmorphans.
Topics: Alkylation; Cyclization; Models, Molecular; Molecular Structure; Morphinans; Stereoisomerism | 2011 |
Probes for narcotic receptor mediated phenomena. 44. Synthesis of an N-substituted 4-hydroxy-5-(3-hydroxyphenyl)morphan with high affinity and selective μ-antagonist activity.
Topics: Animals; Azabicyclo Compounds; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Structure; Morphinans; Narcotic Antagonists; Protein Binding; Receptors, Opioid; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship | 2012 |
Probes for narcotic receptor mediated phenomena. 46. N-substituted-2,3,4,9,10,10a-hexahydro-1H-1,4a-(epiminoethano)phenanthren-6- and 8-ols - carbocyclic relatives of f-oxide-bridged phenylmorphans.
Topics: Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Conformation; Morphinans; Oxides; Receptors, Opioid, mu; Structure-Activity Relationship | 2012 |
Probes for narcotic receptor mediated phenomena. 48. C7- and C8-substituted 5-phenylmorphan opioids from diastereoselective alkylation.
Topics: Alkylation; Animals; Cells, Cultured; CHO Cells; Cricetulus; Crystallography, X-Ray; Dose-Response Relationship, Drug; Humans; Models, Molecular; Molecular Conformation; Morphinans; Receptors, Opioid; Stereoisomerism; Structure-Activity Relationship | 2013 |
Synthesis and Pharmacological Evaluation of Enantiopure N-Substituted Ortho-c Oxide-Bridged 5-Phenylmorphans.
Topics: Crystallography, X-Ray; Isomerism; Morphinans; Oxides; Receptors, Opioid, mu | 2022 |
Discovery of a Potent Highly Biased MOR Partial Agonist among Diastereomeric C9-Hydroxyalkyl-5-phenylmorphans.
Topics: Analgesics, Opioid; Morphinans; Morphine; Receptors, Opioid, mu | 2023 |
A MOR Antagonist with High Potency and Antagonist Efficacy among Diastereomeric C9-Alkyl-Substituted
Topics: Analgesics, Opioid; Morphinans; Morphine; Naltrexone; Receptors, Opioid, mu; Structure-Activity Relationship | 2023 |