Page last updated: 2024-08-16

phenylmethylsulfonyl fluoride and serine

phenylmethylsulfonyl fluoride has been researched along with serine in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199011 (50.00)18.7374
1990's5 (22.73)18.2507
2000's3 (13.64)29.6817
2010's2 (9.09)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Horiuchi, S; Inoue, M; Morino, Y1
Chaloupka, J; Krecková, P; Nesmeyanova, MA; Obdrzálek, V; Zalabák, V1
Bendtzen, K2
Ballesta, JP; Bernabeu, C; Vidales, FJ1
Dao, TL; Schneider, SL1
Aitken, A; Arche, R; Martín, J; Slade, A; Virden, R1
Dunbar, B; Horrocks, AJ; Lindsay, CD; Slade, A; Virden, R1
Ennulat, DJ; Stach, BM; Stach, RW1
Dolphin, PJ; Jauhiainen, M; Ridgway, ND1
Bing, DH; Laura, R; Robison, DJ1
Kishi, H; Kishimoto, S; Kishimoto, T; Miki, Y; Muraguchi, A; Yamamura, Y1
Muszyńska, G; Wojtczak, M1
Bulsink, YB; de Haas, GH; Demleitner, G; Götz, F; Leuveling Tjeenk, M; Slotboom, AJ; Verheij, HM1
Merrifield, RB; Unson, CG1
McGrath, ME; Mirzadegan, T; Schmidt, BF1
Batra, R; Khayat, R; Lagacé, L; Massariol, MJ; Tong, L1
Masuda, T; Ohta, H; Shimada, H; Suzuki, T; Takamiya, K; Tsuchiya, T; Yamada, T1
Choi, SJ; Choi, SW; Firatli, E; Hart, PS; Hart, TC; Ryu, OH; Shen, RF; Wang, G; Wu, WW1
Manonmani, HK; Selvi, AA1
Sevrioukova, I1
Brooks, CL; Goldfarb, NE; Kakkad, S; Li, D; Ostrov, DA; Peña, K; Schumann, NC; Williams, BP1

Other Studies

22 other study(ies) available for phenylmethylsulfonyl fluoride and serine

ArticleYear
Inactivation of gamma-glutamyl transpeptidase by phenylmethanesulfonyl fluoride, a specific inactivator of serine enzymes.
    Biochemical and biophysical research communications, 1978, Jun-29, Volume: 82, Issue:4

    Topics: Animals; Binding Sites; gamma-Glutamyltransferase; Glutathione; Kidney; Kinetics; Phenylmethylsulfonyl Fluoride; Rats; Serine; Sulfones

1978
Protease activity in cells of Bacillus megaterium during derepression.
    Folia microbiologica, 1975, Volume: 20, Issue:4

    Topics: Amino Acids; Bacillus megaterium; Bacterial Proteins; Chloramphenicol; Edetic Acid; Enzyme Repression; Ethanol; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Peptide Hydrolases; Phenanthrolines; Phenylmethylsulfonyl Fluoride; Protoplasts; Serine

1975
Human leukocyte migration inhibitory factor (LIF). I. Effect of synthetic and naturally occurring esterase and protease inhibitors.
    Scandinavian journal of immunology, 1977, Volume: 6, Issue:1-2

    Topics: Aprotinin; Dose-Response Relationship, Drug; Esterases; Fluorides; Humans; Isoflurophate; Lymphocytes; Macrophage Migration-Inhibitory Factors; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Time Factors; Trypsin Inhibitors

1977
Human leukocyte migration inhibitory factor (LIF). II. Partial biochemical characterization of the substrate specificities for this lymphokine.
    Scandinavian journal of immunology, 1977, Volume: 6, Issue:1-2

    Topics: Benzyl Compounds; Binding, Competitive; Carboxylic Acids; Cell Migration Inhibition; Drug Interactions; Esterases; Esters; Humans; Indicators and Reagents; Isoflurophate; Leukocytes; Lymphocytes; Macrophage Migration-Inhibitory Factors; Molecular Weight; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine

1977
Peptidyl transfer ribonucleic acid hydrolase activity of proteinase k.
    Biochemistry, 1979, Sep-18, Volume: 18, Issue:19

    Topics: Endopeptidases; Escherichia coli; Hydrolases; Kinetics; Mitosporic Fungi; Phenylmethylsulfonyl Fluoride; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Serine; Temperature

1979
Effect of Ca2+ and salt on forms of estradiol cytoplasmic receptor in human neoplastic breast tissue.
    Cancer research, 1977, Volume: 37, Issue:2

    Topics: Breast Neoplasms; Calcium; Centrifugation, Density Gradient; Cytosol; Estradiol; Female; Humans; In Vitro Techniques; Peptide Hydrolases; Phenylmethylsulfonyl Fluoride; Potassium Chloride; Protease Inhibitors; Receptors, Estrogen; Serine

1977
Chemical modification of serine at the active site of penicillin acylase from Kluyvera citrophila.
    The Biochemical journal, 1991, Dec-15, Volume: 280 ( Pt 3)

    Topics: Amino Acid Sequence; Binding Sites; Circular Dichroism; Enterobacteriaceae; Kinetics; Molecular Sequence Data; Penicillin Amidase; Phenylmethylsulfonyl Fluoride; Protein Conformation; Sequence Homology, Nucleic Acid; Serine; Substrate Specificity; Sulfhydryl Compounds

1991
Site-directed chemical conversion of serine to cysteine in penicillin acylase from Escherichia coli ATCC 11105. Effect on conformation and catalytic activity.
    European journal of biochemistry, 1991, Apr-10, Volume: 197, Issue:1

    Topics: Amino Acid Sequence; Circular Dichroism; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Penicillanic Acid; Penicillin Amidase; Phenylmethylsulfonyl Fluoride; Protein Conformation; Pyridines; Serine; Sulfur Radioisotopes

1991
Phenylmethylsulfonyl fluoride (PMSF) inhibits nerve growth factor binding to the high affinity (type I) nerve growth factor receptor.
    Biochemical and biophysical research communications, 1986, Jan-29, Volume: 134, Issue:2

    Topics: Animals; Chick Embryo; Dithionitrobenzoic Acid; Epidermal Growth Factor; ErbB Receptors; Ganglia, Spinal; In Vitro Techniques; Kinetics; Phenylmethylsulfonyl Fluoride; Receptors, Cell Surface; Serine; Solubility; Sulfones

1986
Aromatic boronic acids as probes of the catalytic site of human plasma lecithin-cholesterol acyltransferase.
    Biochimica et biophysica acta, 1987, Apr-03, Volume: 918, Issue:2

    Topics: Binding Sites; Boronic Acids; Catalysis; Chromatography; Cysteine; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Phenylmethylsulfonyl Fluoride; Phosphatidylcholine-Sterol O-Acyltransferase; Serine

1987
(p-Amidinophenyl)methanesulfonyl fluoride, an irreversible inhibitor of serine proteases.
    Biochemistry, 1980, Oct-14, Volume: 19, Issue:21

    Topics: Models, Molecular; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Sulfones; Trypsin Inhibitors

1980
The requirement for esterase activation in T cell replacing factor (TRF)-induced IgG production in a human B blastoid cell line.
    Journal of immunology (Baltimore, Md. : 1950), 1982, Volume: 128, Issue:2

    Topics: Adenosine Monophosphate; B-Lymphocytes; Cell Division; Cell Line; Esterases; Humans; Immunoglobulin G; Interleukin-5; Isoflurophate; Lymphokines; Phenylmethylsulfonyl Fluoride; Serine; Tosylarginine Methyl Ester

1982
Is the seryl residue essential for catalytic activity of rat liver arginase?
    Biochemical and biophysical research communications, 1982, Aug-31, Volume: 107, Issue:4

    Topics: Animals; Arginase; Binding Sites; Isoflurophate; Kinetics; Liver; Phenylmethylsulfonyl Fluoride; Protein Binding; Rats; Serine; Sulfones

1982
Inactivation of Staphylococcus hyicus lipase by hexadecylsulfonyl fluoride: evidence for an active site serine.
    Protein engineering, 1994, Volume: 7, Issue:4

    Topics: Bacterial Proteins; Binding Sites; Carboxylic Ester Hydrolases; Cations, Divalent; Disulfides; Micelles; Octoxynol; Phenylmethylsulfonyl Fluoride; Recombinant Proteins; Serine; Staphylococcus; Sulfones

1994
Identification of an essential serine residue in glucagon: implication for an active site triad.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Jan-18, Volume: 91, Issue:2

    Topics: Adenylyl Cyclases; Animals; Binding Sites; Glucagon; In Vitro Techniques; Isoflurophate; Liver; Male; Molecular Structure; Phenylmethylsulfonyl Fluoride; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Serine; Serine Proteinase Inhibitors; Structure-Activity Relationship

1994
Crystal structure of phenylmethanesulfonyl fluoride-treated human chymase at 1.9 A.
    Biochemistry, 1997, Nov-25, Volume: 36, Issue:47

    Topics: Binding Sites; Chymases; Chymotrypsin; Computer Simulation; Crystallography, X-Ray; Histidine; Humans; Models, Molecular; Phenylmethylsulfonyl Fluoride; Protein Conformation; Serine; Serine Endopeptidases; Substrate Specificity

1997
Investigating the role of histidine 157 in the catalytic activity of human cytomegalovirus protease.
    Biochemistry, 2001, May-29, Volume: 40, Issue:21

    Topics: Alanine; Binding Sites; Catalytic Domain; Conserved Sequence; Crystallization; Crystallography, X-Ray; Cytomegalovirus; Dimerization; Glutamic Acid; Glutamine; Histidine; Humans; Kinetics; Mutagenesis, Site-Directed; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Serine; Serine Endopeptidases; Solvents

2001
Chlorophyllase as a serine hydrolase: identification of a putative catalytic triad.
    Plant & cell physiology, 2003, Volume: 44, Issue:1

    Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carboxylic Ester Hydrolases; Catalysis; Chenopodium album; Enzyme Inhibitors; Histidine; Hydrolysis; Isoflurophate; Lipase; Molecular Sequence Data; Morpholines; Mutagenesis, Site-Directed; Mutation; p-Chloromercuribenzoic Acid; Phenylmethylsulfonyl Fluoride; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases

2003
Proteolysis of macrophage inflammatory protein-1alpha isoforms LD78beta and LD78alpha by neutrophil-derived serine proteases.
    The Journal of biological chemistry, 2005, Apr-29, Volume: 280, Issue:17

    Topics: Amino Acid Sequence; Cathepsin G; Cathepsins; Chemokine CCL3; Chemokine CCL4; Chemokines; Chemotaxis; Cytokines; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Inflammation; Macrophage Inflammatory Proteins; Mass Spectrometry; Molecular Sequence Data; Myeloblastin; Neutrophils; Pancreatic Elastase; Peptides; Phenylmethylsulfonyl Fluoride; Protease Inhibitors; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Time Factors

2005
Purification and characterization of carbon-phosphorus bond-cleavage enzyme from glyphosate degrading Pseudomonas putida T5.
    Preparative biochemistry & biotechnology, 2015, Volume: 45, Issue:4

    Topics: Catalytic Domain; Chromatography, Gel; Enzyme Inhibitors; Enzyme Stability; Glycine; Glyphosate; Hydrogen-Ion Concentration; Kinetics; Lyases; Metals; Phenylmethylsulfonyl Fluoride; Pseudomonas putida; Serine; Substrate Specificity; Temperature

2015
Interaction of Human Drug-Metabolizing CYP3A4 with Small Inhibitory Molecules.
    Biochemistry, 2019, 02-19, Volume: 58, Issue:7

    Topics: Binding Sites; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Fluconazole; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Inactivation, Metabolic; Metyrapone; Phenylmethylsulfonyl Fluoride; Serine

2019
2.1 Å crystal structure of the Mycobacterium tuberculosis serine hydrolase, Hip1, in its anhydro-form (Anhydrohip1).
    Biochemical and biophysical research communications, 2022, 11-19, Volume: 630

    Topics: Crystallography, X-Ray; Ligands; Lipids; Molecular Docking Simulation; Mycobacterium tuberculosis; Phenylmethylsulfonyl Fluoride; Serine; Serine Proteases; Serine Proteinase Inhibitors; Sulfones

2022