phenylbutazone has been researched along with warfarin in 165 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 123 (74.55) | 18.7374 |
| 1990's | 20 (12.12) | 18.2507 |
| 2000's | 13 (7.88) | 29.6817 |
| 2010's | 7 (4.24) | 24.3611 |
| 2020's | 2 (1.21) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Afzelius, L; Andersson, TB; Baroni, M; Cruciani, G; Karlén, A; Masimirembwa, CM; Mecucci, S; Zamora, I | 1 |
| Hadjipavlou-Litina, DJ; Kontogiorgis, CA | 1 |
| Ho, A; Marotti, KR; Romero, DL; Sarver, RW; Thorarensen, A; Tian, F | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Gozalbes, R; Pineda-Lucena, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Bajusz, D; Balogh, GT; Dargó, G; Müller, J; Simon, K | 1 |
| Bachmann, KA; Burkman, AM | 1 |
| Barry, BW; Braybrooks, MP | 1 |
| Aarons, LJ; Rowland, M; Schary, WL | 1 |
| Kampffmeyer, H | 1 |
| Robinson, DS | 1 |
| Blanchard, J; Sorby, DL; Tozer, TN; Tuck, LD | 1 |
| Cameron, JS; Clark, WF; George, CR | 1 |
| Gugler, R | 1 |
| d'Athis, P; Lecomte, M; Tillement, JP; Zini, R | 1 |
| Reinicke, C; Wessel, G | 1 |
| Kapoor, A; Veronich, K; White, G | 1 |
| Ciana, A; Crescenzi, V; Manzini, G | 1 |
| O'Reilly, RA | 5 |
| Bianchi, G; Cerri, B; Chierichetti, S | 1 |
| Brown, KF; Crooks, MJ | 1 |
| Belpaire, FM; Bogaert, MG; Mussche, MM | 1 |
| Ackermann, E | 1 |
| Brady, LP | 1 |
| Dittrich, A; Riedel, H; Schumann, K | 1 |
| Rippie, EG | 1 |
| Assandri, A; Perazzi, A | 1 |
| Bachmann, KA; Burkman, AM; Feller, DR | 1 |
| Freilinger, G; Schürer-Waldheim, H | 1 |
| Himberg, JJ; Julkunen, RJ | 1 |
| Lewis, RJ; Rowland, M; Schary, WL | 1 |
| Lovering, EG; McGilveray, IJ; McMillan, I; Tostowaryk, W | 1 |
| De Clerck, F; Reneman, R; Vermylen, J | 1 |
| Bull, J; Mackinnon, J | 1 |
| Sloane, DJ; Whaley, K | 1 |
| Johnsson, H; Olsson, P | 1 |
| Davies, RO; Gagnon, MA; McLean, WM; Ruedy, J; Thompson, WG; Vitti, TG; Wilson, TW | 1 |
| Bowmer, CJ; Panjehshahin, MR; Yates, MS | 2 |
| Hage, DS; Noctor, TA; Wainer, IW | 1 |
| Cohen-Luria, R; Danon, A; Rimon, G | 1 |
| Adachi, T; Hirano, K; Ito, Y; Sugiura, M; Watanabe, Y | 1 |
| Cittanova, N; Dessen, P; Hervé, F; Martin, MT; Rajkowski, KM | 1 |
| Cittanova, N; Dessen, P; Hervé, F; Martin, MT; Rajkowski, K | 2 |
| Dirr, HW; Schabort, JC | 1 |
| Kragh-Hansen, U | 1 |
| Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y | 1 |
| Crowe, JT; Mathur, PP; Sancilio, LF; Taylor, MA | 1 |
| van Miert, AS | 1 |
| Hucker, HB; Stauffer, SC; White, SE | 1 |
| Jatlow, P | 1 |
| Coldwell, BB; Grice, HC; Zawidzka, ZZ | 1 |
| Cepelák, V; Grimová, J; Nĕmecek, O; Roubal, Z | 1 |
| McQueen, EG | 1 |
| Rawlins, MD; Smith, SE | 2 |
| Fontaine, L; Grand, M; Merle, S; Quentin, Y | 1 |
| Vesell, ES | 1 |
| Hahn, I; Krieglstein, G; Krieglstein, J; Tschentscher, K | 1 |
| Sellers, E; Weser, JK | 1 |
| Cooper, JK; McGilveray, IJ; Midha, KK | 1 |
| Bachmann, KA | 1 |
| Deutschman, P; Muirden, KD; Phillips, M | 1 |
| Eipe, J | 1 |
| Fossati, C | 1 |
| Nies, AS | 1 |
| Seiler, K | 1 |
| Hsu, PL; Jun, HW; Luzzi, LA | 1 |
| Cepelák, V; Cepeláková, H; Nĕmecek, O; Roubal, Z | 1 |
| Cepelák, V; Cepeláková, H; Dlabac, A; Grimová, J; Roubal, Z | 1 |
| Eckhardt, W; Rudolph, R; Sauer, H; Schubert, WR; Undeutsch, D | 1 |
| Jaminet, F | 1 |
| Brozović, M; Gurd, LJ | 1 |
| Mattei, C; Singlas, E; Tillement, JP; Zini, R | 1 |
| Gubler, HU; Haefliger, W; Hauser, D; Wiesinger, D | 1 |
| Bickel, MH; Steele, JW | 1 |
| Breckenridge, A; Chan, KK; Lewis, RJ; Orme, M; Roland, M; Schary, W; Trager, WF | 1 |
| d' Athis, P; Tillement, JP; Vassent, G; Zini, R | 1 |
| MacLennan, WJ | 1 |
| Aggeler, PM; O'Reilly, RA | 1 |
| Berger, W; Spring, P | 1 |
| Altland, K; Goedee, HW | 1 |
| Jähnchen, E; Levy, G | 1 |
| Bullock, FJ; Coffey, JJ; Schoenemann, PT | 1 |
| Koch-Weser, J; Sellers, EM | 1 |
| Abrams, WB; Reich, S; Solomon, HM; Spirt, N | 1 |
| Breckenridge, A | 1 |
| Azarnoff, DL; Mustala, OO | 1 |
| Griner, PF; Kleinman, PD | 1 |
| Held, H; Kaminski, B; von Oldershausen, HF | 1 |
| Abdel-Maguid, R; el-Dakhakhny, M; Mahfouz, M | 1 |
| Levy, G; O'Reilly, RA | 1 |
| Naess, K | 1 |
| Brody, BB | 1 |
| Janků, K; Martincík, J; Smíd, J | 1 |
| Schrogie, JJ; Solomon, HM; Williams, D | 1 |
| Duckert, F; Seiler, K | 1 |
| Awalt, LF | 1 |
| Bailey, KR; Gallo, DG; Sheffner, AL | 1 |
| Mayer, GA | 1 |
| Aggeler, PM; Kowitz, PE; Leong, L; O'Reilly, RA | 1 |
| Hoffbrand, BI; Kininmonth, DA | 1 |
| Schrogie, JJ; Solomon, HM | 1 |
| Dayton, PG; Sanders, JE | 1 |
| Blunnie, WP; Murray, JM | 1 |
| Banfield, C; Chan, E; O'Reilly, R; Rowland, M | 1 |
| Fehske, KJ; Müller, WE; Schläfer, U; Wollert, U | 1 |
| Felder, M | 1 |
| Goldberg, DM | 1 |
| Sebille, B; Thuaud, N; Tillement, JP | 1 |
| Ellis, GM; Madsen, BW | 1 |
| Goulart, DA; O'Reilly, RA | 1 |
| Howald, W; Motley, CH; O'Reilly, RA; Trager, WF | 1 |
| Lai, CM; Levy, G; Yacobi, A | 1 |
| Madsen, BW; Tearne, PD | 1 |
| Hayes, AH | 1 |
| Barre, J; Campos, H; d'Athis, P; Prandota, J; Tillement, JP | 1 |
| Aubry, AF; Rahim, S | 1 |
| Ferrer, JM; Marquínez, MA; Ruiz de Gordoa, JC; Zatón, AM | 1 |
| Nakasaka, T; Okabe, N | 1 |
| Aki, H; Yamamoto, M | 1 |
| Ballard, P; Law, B; Malone, MD | 1 |
| Hashizume, N; Okabe, N | 1 |
| Imai, T; Maruyama, T; Okada, T; Otagiri, M; Rahman, MH | 1 |
| Chan, E; McLachlan, AJ; Rowland, M | 1 |
| Kragh-Hansen, U; Maruyama, T; Otagiri, M; Yamasaki, K | 1 |
| Aubry, AF; Markoglou, N; McGann, A | 1 |
| He, J; Nakagawa, T; Shibukawa, A; Tokunaga, S | 1 |
| Bertucci, C; Wainer, IW | 1 |
| Kosa, T; Maruyama, T; Otagiri, M | 1 |
| Kosa, T; Maruyama, T; Otagiri, M; Sakai, N; Yahara, S; Yonemura, N | 1 |
| Erim, FB; Kraak, JC | 1 |
| Goto, M; Maruyama, T; Matsunaga, H; Otagiri, M; Takadate, A; Tsutsumi, Y | 1 |
| Baguley, BC; Jameson, MB; Kestell, P; Paxton, JW; Thompson, PI; Tingle, MD; Zhou, SF | 1 |
| Asakawa, N; Ishihama, Y; Miwa, T | 1 |
| Russeva, VN; Zhivkova, ZD | 1 |
| MULLER, K | 1 |
| GUGGISBERG, W; MONTIGEL, C | 1 |
| FOX, SL | 1 |
| BECKER, F; DENNIG, H; THALER, A | 1 |
| EISEN, MJ | 1 |
| MORELLI, AC | 1 |
| BURNS, JJ; CONNEY, AH | 1 |
| Kosaka, T; Kumamoto, K; Nakai, D; Sakikawa, C; Tokui, T | 1 |
| Kwon, BM; Lee, CH; Lee, KJ; Shan, R | 1 |
| Jung, M; Mathias, U | 1 |
| Kuroda, Y; Saito, M; Sakai, H; Yamaoka, T | 1 |
| Fujishima, M; Hiratsuka, A; Izawa, T; Masuda, Y; Nishiyama, T; Ogura, K; Ohnuma, T | 1 |
| Bell, RG; Kelly, LJ | 1 |
| Kabir, MZ; Kandandapani, S; Mohamad, SB; Ridzwan, NFW; Tayyab, S | 1 |
15 review(s) available for phenylbutazone and warfarin
| Article | Year |
|---|---|
The role of platelets in glomerulonephritis.
Topics: Adenosine; Antidepressive Agents; Aspirin; Blood Platelets; Complement System Proteins; Endothelium; Glomerulonephritis; Hemostasis; Heparin; Histamine H1 Antagonists; Humans; Immunity; Immunoglobulins; Indomethacin; Kidney Diseases; Meclofenamic Acid; Mopidamol; Phagocytosis; Phenylbutazone; Platelet Aggregation; Prostaglandins; Pyrimidines; Sulfinpyrazone; Tranquilizing Agents; Warfarin | 1975 |
Vitamin K and the oral anticoagulant drugs.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anticoagulants; Aspirin; Barbiturates; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Chemical Phenomena; Chemistry; Cholestyramine Resin; Disulfiram; Diuretics; Drug Interactions; Ethanol; Female; Humans; Infant, Newborn; Male; Phenylbutazone; Prothrombin; Receptors, Drug; Vitamin K; Warfarin | 1976 |
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin | 1985 |
The pharmacodynamics of the oral anticoagulant drugs.
Topics: Administration, Oral; Animals; Anticoagulants; Blood Coagulation; Blood Coagulation Factors; Blood Proteins; Clofibrate; Coumarins; Dicumarol; Disulfiram; Ethyl Biscoumacetate; Female; Heparin; Intestinal Absorption; Liver; Phenylbutazone; Protein Binding; Prothrombin; Prothrombin Time; Rabbits; Rats; Salicylates; Sulfonamides; Vitamin K; Vitamin K Deficiency; Warfarin | 1974 |
Hazards of anticoagulant treatment: other drugs, other diseases.
Topics: Administration, Oral; Animals; Anticoagulants; Barbiturates; Biological Transport; Blood Coagulation Factors; Clofibrate; Cycloheptanes; Depression, Chemical; Dicumarol; Disulfiram; Drug Interactions; Drug Synergism; Feces; Female; Half-Life; Humans; Hypoprothrombinemias; Infant, Newborn; Phenylbutazone; Pregnancy; Prothrombin Time; Rats; Receptors, Drug; Serum Albumin; Vitamin K Deficiency; Warfarin | 1973 |
Recent progress in pharmacogenetics.
Topics: Adult; Aged; Alcohol Oxidoreductases; Antipyrine; Asian People; Child, Preschool; Cholinesterases; Cyanides; Dicumarol; Diseases in Twins; Drug Hypersensitivity; Erythrocytes; Favism; Female; Glucosephosphate Dehydrogenase Deficiency; Hemoglobins; Humans; Isoniazid; Liver; Male; Metabolism, Inborn Errors; Middle Aged; Pharmacogenetics; Phenylbutazone; Phenylthiourea; Phenytoin; Pregnancy; Primaquine; Twins; Warfarin | 1969 |
Drug interactions with coumarin anticoagulants. 2.
Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide | 1971 |
Drugs affecting therapy with anticoagulants.
Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Estrogens; Ethanol; Heparin; Humans; Hypnotics and Sedatives; Phenylbutazone; Phenytoin; Salicylates; Thyroxine; Tolbutamide; Vitamin K | 1972 |
[Liver damage due to drugs. I].
Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Halothane; Humans; Imipramine; Liver; Methotrexate; Methyldopa; Nicotinic Acids; Oxacillin; Phenylbutazone; Testosterone; Tetracycline | 1974 |
Drug interactions.
Topics: Anabolic Agents; Antidepressive Agents; Biological Transport, Active; Cholestyramine Resin; Clofibrate; Drug Interactions; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kaolin; Kidney; Pharmaceutical Preparations; Phenylbutazone; Probenecid; Protein Binding; Thyroxine; Warfarin | 1974 |
Determinants of the response to oral anticoagulant drugs in man.
Topics: Administration, Oral; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anticoagulants; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Clofibrate; Coumarins; Diuresis; Dogs; Heparin; Humans; Hypnotics and Sedatives; Liver Diseases; Metabolic Diseases; Phenylbutazone; Rats; Salicylates; Sulfonamides; Thrombosis; Uremia; Vitamin K | 1970 |
[Genetically dependent variability of drug effects].
Topics: Anemia, Hemolytic; Anesthesia, General; Anesthetics; Animals; Antipyrine; Apnea; Atropine; Body Temperature; Coumarins; Cyanosis; Deficiency Diseases; Dexamethasone; Dogs; Drug Tolerance; Enzymes; Female; Glucosephosphate Dehydrogenase; Humans; Intraocular Pressure; Isonicotinic Acids; Male; Meperidine; Mice; Oxyphenbutazone; Pharmacogenetics; Phenacetin; Phenylbutazone; Phenytoin; Proteins; Rabbits; Rats; Succinylcholine | 1970 |
Dose-dependent pharmacokinetics: emphasis on phase I metabolism.
Topics: 2,4,5-Trichlorophenoxyacetic Acid; Adolescent; Adult; Age Factors; Aged; Animals; Antineoplastic Agents; Child; Child, Preschool; Coumarins; Dioxanes; Dose-Response Relationship, Drug; Humans; Infant; Infant, Newborn; Kinetics; Mathematics; Middle Aged; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Tissue Distribution | 1983 |
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin | 1980 |
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM.
Topics: Aminopyrine; Chloramphenicol; Coumarins; Dicumarol; Humans; Metabolism; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenobarbital; Phenylbutazone | 1964 |
1 trial(s) available for phenylbutazone and warfarin
| Article | Year |
|---|---|
Comparison of feprazone and phenylbutazone interaction with warfarin in man.
Topics: Adult; Anti-Inflammatory Agents; Anticoagulants; Clinical Trials as Topic; Drug Interactions; Female; Feprazone; Humans; Male; Middle Aged; Phenylbutazone; Prothrombin Time; Pyrazoles; Time Factors; Warfarin | 1975 |
149 other study(ies) available for phenylbutazone and warfarin
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Conformer- and alignment-independent model for predicting structurally diverse competitive CYP2C9 inhibitors.
Topics: Amino Acids; Aryl Hydrocarbon Hydroxylases; Binding Sites; Cytochrome P-450 CYP2C9; Enzyme Inhibitors; Models, Molecular; Molecular Conformation; Molecular Structure; Quantitative Structure-Activity Relationship | 2004 |
Synthesis and antiinflammatory activity of coumarin derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Coumarins; Cyclooxygenase Inhibitors; Edema; Female; Free Radical Scavengers; Immunologic Factors; Lipoxygenase Inhibitors; Male; Mannich Bases; Rats; Rats, Inbred F344; Structure-Activity Relationship; Superoxides | 2005 |
Human serum albumin binding assay based on displacement of a non selective fluorescent inhibitor.
Topics: Albumins; Anti-Bacterial Agents; Binding Sites; Calorimetry; Fluorescence; Humans; ortho-Aminobenzoates; Protein Binding | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
QSAR-based solubility model for drug-like compounds.
Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Human Serum Albumin Binding in a Vial: A Novel UV-pH Titration Method To Assist Drug Design.
Topics: Binding Sites; Chemistry, Pharmaceutical; Drug Design; Humans; Hydrogen-Ion Concentration; Molecular Docking Simulation; Pharmaceutical Preparations; Protein Binding; Serum Albumin, Human; Spectrophotometry, Ultraviolet; Titrimetry | 2020 |
Phenylbutazone-warfarin interaction in the dog.
Topics: Animals; Biological Availability; Dogs; Drug Interactions; Half-Life; Hypoprothrombinemias; Male; Phenylbutazone; Protein Binding; Prothrombin; Warfarin | 1975 |
Proceedings: Influence of a mucin model system upon the bioavailability of phenylbutazone and warfarin sodium from the small intestine.
Topics: Animals; Biological Availability; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Models, Biological; Mucins; Phenylbutazone; Rats; Swine; Warfarin | 1975 |
An in vitro study of drug displacement interactions: warfarin-salicylate and warfarin-phenylbutazone.
Topics: Animals; Binding, Competitive; Cattle; Dialysis; Kinetics; Phenylbutazone; Protein Binding; Salicylates; Warfarin | 1979 |
[Drug interactions].
Topics: Binding, Competitive; Cardiac Glycosides; Coumarins; Drug Interactions; Drug Synergism; Griseofulvin; Humans; Mycoses; Phenylbutazone; Protein Binding | 1979 |
The application of basic principles of drug interaction to clinical practice.
Topics: Aged; Aspirin; Binding Sites; Binding, Competitive; Depression, Chemical; Drug Interactions; Drug Synergism; Drug Therapy; Gastrointestinal Hemorrhage; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kidney; Kinetics; Liver; Male; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Receptors, Drug; Stimulation, Chemical; Warfarin | 1975 |
Investigation of drug-albumin interactions using spin-labeled bovine serum albumin.
Topics: Animals; Cattle; Drug Interactions; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Phenylbutazone; Protein Binding; Protein Conformation; Serum Albumin, Bovine; Spin Labels; Triazines; Ultracentrifugation; Warfarin | 1975 |
[Drug interactions in therapy using coumarin derivatives].
Topics: Allopurinol; Anti-Inflammatory Agents; Barbiturates; Biological Availability; Cholestyramine Resin; Coumarins; Drug Interactions; Humans; Metronidazole; Phenylbutazone; Rifampin; Sulfonamides; Tolbutamide | 1979 |
Phenytoin binding to human albumin.
Topics: Anilino Naphthalenesulfonates; Fatty Acids, Nonesterified; Humans; Imipramine; Palmitic Acids; Phenylbutazone; Phenytoin; Protein Binding; Serum Albumin; Warfarin | 1979 |
[Undesirable drug interactions. Notes on general principles].
Topics: Acetylation; Barbiturates; Coumarins; Drug Antagonism; Drug Interactions; Drug Synergism; Humans; Isoniazid; Monoamine Oxidase Inhibitors; Phenylbutazone; Sympathomimetics; Therapeutic Equivalency | 1979 |
Effects of phenylbutazone, tolbutamide, and clofibric acid on binding of racemic warfarin and its enantiomers to human serum albumin.
Topics: Binding, Competitive; Clofibrate; Clofibric Acid; Humans; Kinetics; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism; Tolbutamide; Warfarin | 1979 |
The interaction of serum albumins with various drugs in aqueous solution. Gel permeation, calorimetric, and fluorescence data.
Topics: Animals; Binding Sites; Calorimetry; Cattle; Chromatography, Gel; Fluoresceins; Humans; Kinetics; Oxazepam; Phenylbutazone; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Warfarin | 1979 |
Displacement of tolbutamide, glibencalmide and chlorpropamide from serum albumin by anionic drugs.
Topics: Acetaminophen; Animals; Cattle; Chlorpropamide; Dialysis; Glyburide; Humans; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfaphenazole; Tolbutamide; Warfarin | 1976 |
Influence of acute renal failure on the protein binding of drugs in animals and in man.
Topics: Acute Kidney Injury; Animals; Blood Proteins; Cats; Digitoxin; Dogs; Female; Guinea Pigs; Humans; Male; Papaverine; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Quinidine; Rabbits; Rats; Species Specificity; Time Factors; Uranyl Nitrate; Urea; Warfarin | 1977 |
[Pharmacokinetics in liver cirrhosis].
Topics: Aminopyrine; Biotransformation; Chloramphenicol; Coumarins; Half-Life; Humans; Kinetics; Liver Cirrhosis; Pharmaceutical Preparations; Phenylbutazone; Salicylates; Tolbutamide | 1977 |
A multifaceted approach to prevention of thromboembolism: a report of 529 cases.
Topics: Aspirin; Bandages; Dextrans; Exercise Therapy; Heparin; Hip Joint; Humans; Joint Prosthesis; Phenylbutazone; Postoperative Complications; Prospective Studies; Pulmonary Embolism; Thromboembolism; Thrombophlebitis; Warfarin | 1977 |
[Treatment of thrombophlebitis during pregnancy].
Topics: Bandages; Coumarins; Exercise Therapy; Female; Heparin; Humans; Phenylbutazone; Posture; Pregnancy; Pregnancy Complications, Hematologic; Thrombophlebitis; Varicose Veins | 1977 |
Thermodynamics of fatty acid anion displacement of warfarin and phenylbutazone from human albumin.
Topics: Binding Sites; Fatty Acids; Humans; Phenylbutazone; Protein Binding; Serum Albumin; Thermodynamics; Warfarin | 1976 |
Competition between diftalone and other drugs for the binding site(s) on human serum albumin.
Topics: Acetaminophen; Aspirin; Binding Sites; Dexamethasone; Drug Interactions; Humans; Indomethacin; Phenobarbital; Phenylbutazone; Phthalazines; Protein Binding; Pyridazines; Serum Albumin; Temperature; Tolbutamide; Warfarin | 1976 |
Effect of phenylbutazone on the metabolic disposition of warfarin in the dog.
Topics: Animals; Dogs; Fluorometry; Half-Life; Male; Microsomes, Liver; Phenylbutazone; Warfarin | 1976 |
[Iatrogenic tissue damage and its treatment (author's transl)].
Topics: Bone Nails; Coumarins; Dicloxacillin; Electrosurgery; Humans; Iatrogenic Disease; Necrosis; Phenylbutazone | 1976 |
Dry polyacrylamide batch method for studying drug protein binding.
Topics: Chromatography, Gel; Humans; Phenylbutazone; Protein Binding; Quinidine; Serum Albumin; Sulfadiazine; Sulfisoxazole; Warfarin | 1976 |
Warfarin-phenylbutazone interaction in man: a long term multiple dose study.
Topics: Adult; Drug Interactions; Humans; Hydroxylation; Male; Phenylbutazone; Time Factors; Warfarin | 1975 |
Comparative bioavailabilities from truncated blood level curves.
Topics: Acetaminophen; Aminosalicylic Acids; Biological Availability; Biopharmaceutics; Chloramphenicol; Chlordiazepoxide; Digoxin; Humans; Isoniazid; Kinetics; Pharmaceutical Preparations; Phenylbutazone; Sulfamethizole; Tetracycline; Time Factors; Warfarin | 1975 |
Effects of suprofen, an inhibitor of prostaglandin biosynthesis, on platelet function, plasma coagulation and fibrinolysis II. In vivo experiments.
Topics: Adenosine Diphosphate; Animals; Aspirin; Blood Coagulation; Blood Platelets; Collagen; Dogs; Fibrinolysis; Guinea Pigs; Hemostasis; Male; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Platelet Aggregation; Prostaglandin Antagonists; Pyrimidines; Rats; Thiophenes; Time Factors; Warfarin | 1975 |
Phenylbutazone and anticoagulant control.
Topics: Adult; Aged; Drug Interactions; Female; Hemorrhage; Humans; Male; Middle Aged; Phenylbutazone; Warfarin | 1975 |
Studies of the action of some anti-inflammatory drugs on complement mediated immune haemolysis.
Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Reactions; Cloxacillin; Complement System Proteins; Dialysis; Hemolysis; Humans; Isoniazid; Phenylbutazone; Prednisolone; Sodium Salicylate; Warfarin | 1975 |
Interference on the haemostasis in dogs with induced coagulopathies by drugs affecting the platelet function.
Topics: Afibrinogenemia; Animals; Aspirin; Batroxobin; Blood Coagulation; Blood Coagulation Disorders; Blood Platelets; Dogs; Hemostasis; Peptide Hydrolases; Phenylbutazone; Warfarin | 1976 |
Letter: Drug bioavailability.
Topics: Biological Availability; Biopharmaceutics; Digoxin; Phenylbutazone; Phenytoin; Warfarin | 1976 |
A comparison of drug binding sites on mammalian albumins.
Topics: Albumins; Animals; Binding Sites; Binding, Competitive; Cattle; Dansyl Compounds; Diazepam; Dogs; Fatty Acids, Nonesterified; Fluorescence; Horses; Humans; Hydrogen-Ion Concentration; Kinetics; Nitrophenols; Phenylbutazone; Rats; Sarcosine; Sheep; Warfarin | 1992 |
Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase.
Topics: Allosteric Site; Binding, Competitive; Caprylates; Chromatography, High Pressure Liquid; Humans; Ketoprofen; Oxazepam; Pharmaceutical Preparations; Phenylbutazone; Serum Albumin; Stereoisomerism; Suprofen; Tolbutamide; Warfarin | 1992 |
Effect of valproic acid, its unsaturated metabolites and some structurally related fatty acids on the binding of warfarin and dansylsarcosine to human albumin.
Topics: Binding Sites; Binding, Competitive; Dansyl Compounds; Diazepam; Fatty Acids; Fatty Acids, Unsaturated; Humans; In Vitro Techniques; Phenylbutazone; Protein Binding; Sarcosine; Serum Albumin; Structure-Activity Relationship; Valproic Acid; Warfarin | 1991 |
Fatty acid binding protein (FABP) modulates prostaglandin E binding to rat epididymal adipocyte membrane similarly to albumin.
Topics: Adipose Tissue; Animals; Carrier Proteins; Cell Membrane; Diazepam; Dinoprostone; Epididymis; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; GTP-Binding Proteins; In Vitro Techniques; Male; Neoplasm Proteins; Nerve Tissue Proteins; Phenylbutazone; Protein Binding; Rats; Serum Albumin; Warfarin | 1990 |
Drug-binding properties of human alpha-foetoprotein.
Topics: Alcohols; alpha-Fetoproteins; Binding Sites; Humans; Ligands; Phenylbutazone; Serum Albumin; Spectrometry, Fluorescence; Tryptophan; Warfarin | 1985 |
Drug-binding properties of rat alpha-foetoprotein. Specificities of the phenylbutazone-binding and warfarin-binding sites.
Topics: alpha-Fetoproteins; Animals; Bilirubin; Binding Sites; Binding, Competitive; Estradiol; Fatty Acids; Ligands; Phenylbutazone; Protein Binding; Rats; Thyroxine; Warfarin | 1986 |
Participation of the lone tryptophan residue of rat alpha-foetoprotein in its drug-binding sites. Comparison with rat serum albumin.
Topics: alpha-Fetoproteins; Animals; Binding Sites; Phenylbutazone; Protein Binding; Rats; Serum Albumin; Spectrometry, Fluorescence; Tryptophan; Warfarin | 1987 |
Characterization of the aflatoxin B1-binding site of rat albumin.
Topics: Aflatoxin B1; Aflatoxins; Animals; Binding Sites; Binding, Competitive; Cholic Acids; Ligands; Phenylbutazone; Rats; Serum Albumin; Solubility; Spectrometry, Fluorescence; Warfarin | 1987 |
Evidence for a large and flexible region of human serum albumin possessing high affinity binding sites for salicylate, warfarin, and other ligands.
Topics: Apazone; Binding Sites; Binding, Competitive; Chlorpropamide; Diazepam; Humans; Iopanoic Acid; Kinetics; Ligands; Phenylbutazone; Protein Binding; Salicylates; Salicylic Acid; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin | 1988 |
Interaction between warfarin and nonsteroidal anti-inflammatory drugs (NSAIDs) in rats.
Topics: Animals; Anti-Inflammatory Agents; Dose-Response Relationship, Drug; Drug Interactions; Fasting; Male; Phenylbutazone; Prothrombin Time; Rats; Rats, Inbred Strains; Time Factors; Warfarin | 1985 |
[An undesirable drug interaction in horses? Complications which can occur during the administration of coumarin derivatives and phenylbutazone].
Topics: Animals; Coumarins; Dogs; Drug Interactions; Horse Diseases; Horses; Phenylbutazone; Vitamin K | 1985 |
Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys.
Topics: Acetamides; Animals; Anticholesteremic Agents; Antipyrine; Aspirin; Blood Proteins; Carbon Isotopes; Chlorothiazide; Clofibrate; Dicumarol; Digitoxin; Drug Interactions; Fluorine; Glycolates; Half-Life; Haplorhini; Humans; Hypolipidemic Agents; Indomethacin; Macaca; Phenothiazines; Phenylbutazone; Salicylates; Warfarin | 1972 |
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences.
Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin | 1973 |
Effect of non-narcotic analgesics on anticoagulant-induced hypoprothrombinemia in rats.
Topics: Acetaminophen; Acetanilides; Administration, Oral; Animals; Antipyrine; Aspirin; Blood Coagulation; Dicumarol; Female; Hypoprothrombinemias; Injections, Intraperitoneal; Male; Phenacetin; Phenindione; Phenylbutazone; Rats; Salicylamides; Sodium Salicylate; Species Specificity; Time Factors; Warfarin | 1972 |
Effects of nonsteroid anti-inflammatory agents and some dicoumarol derivatives on platelet aggregation, fibrinolysis and stabilization of cell membrane in vitro.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Cell Membrane; Chloroquine; Coumarins; Depression, Chemical; Dicumarol; Erythrocytes; Fibrinolysis; Flufenamic Acid; Hemolysis; Humans; Hypotonic Solutions; In Vitro Techniques; Indomethacin; Inflammation; Mefenamic Acid; Oxyphenbutazone; Phenylbutazone; Phenylpropionates; Platelet Adhesiveness; Pyrazoles; Receptors, Drug; Structure-Activity Relationship | 1972 |
Drug displacement from protein-binding and redistributional interactions.
Topics: Animals; Blood Proteins; Carboxylic Acids; Clofibrate; DDT; Dieldrin; Guanidines; Hexachlorocyclohexane; Humans; Kinetics; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Protein Binding; Rats; Sheep; Ultrafiltration; Warfarin | 1974 |
Prediction of drug oxidation rates in man: lack of correlation with serum gamma-glutamyl transpeptidase and urinary excretion of D-glucaric acid and 6 beta-hydroxycortisol.
Topics: Adipates; Adult; Antipyrine; Biopharmaceutics; gamma-Glutamyltransferase; Half-Life; Humans; Hydroxycorticosteroids; Oxidation-Reduction; Pharmaceutical Preparations; Phenylbutazone; Smoking; Sugar Acids; Warfarin | 1974 |
[Comparative anti-inflammatory action of anticoagulant substances. Mode of action of phenylindanedione].
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Anticoagulants; Aspirin; Carrageenan; Coumarins; Dicumarol; Edema; ortho-Aminobenzoates; Phenindione; Phenylbutazone; Radiation Injuries, Experimental; Rats; Warfarin | 1965 |
Distribution of chlorpromazine in a simplified blood influenced by various drugs.
Topics: Acetazolamide; Animals; Antidepressive Agents; Benzoates; Binding Sites; Binding, Competitive; Cattle; Chlorothiazide; Chlorpromazine; Coumarins; Deoxycholic Acid; Erythrocytes; Fatty Acids; Indomethacin; Phenylbutazone; Phenytoin; Probenecid; Protein Binding; Quinine; Salicylates; Serum Albumin, Bovine; Solubility; Sulfonamides; Suramin; Tetracycline; Thiopental | 1973 |
GLC determination of plasma levels of warfarin.
Topics: Chromatography, Gas; Diazonium Compounds; Humans; Indicators and Reagents; Male; Mass Spectrometry; Methods; Methylation; Phenylbutazone; Spectrophotometry, Ultraviolet; Warfarin | 1974 |
Rapid determination of the concentration of unbound warfarin in human plasma.
Topics: Dialysis; Humans; Methods; Phenylbutazone; Protein Binding; Spectrometry, Fluorescence; Ultrafiltration; Warfarin | 1974 |
The binding of sodium warfarin to plasma albumin and its displacement by phenylbutazone.
Topics: Binding Sites; Blood Protein Electrophoresis; Calorimetry; Carbon Radioisotopes; Chromatography, Thin Layer; Coumarins; Dialysis; Drug Interactions; Humans; Hydrogen-Ion Concentration; Kinetics; Oxyphenbutazone; Phenylbutazone; Protein Binding; Prothrombin; Serum Albumin; Temperature; Thermodynamics; Time Factors; Warfarin | 1973 |
Competition between salicylate and other drugs in binding to human serum protein in vitro.
Topics: Analgesics; Anti-Inflammatory Agents; Blood Proteins; Carbon Radioisotopes; Dialysis; Drug Interactions; Humans; In Vitro Techniques; Indomethacin; Phenylbutazone; Phenylpropionates; Protein Binding; Salicylates; Tritium; Warfarin | 1974 |
Sodium warfarin.
Topics: Half-Life; Humans; Kidney; Kinetics; Phenylbutazone; Protein Binding; Prothrombin Time; Sodium; Solubility; Time Factors; Warfarin | 1972 |
[Defect in oral anticoagulation. Etiology and explanation].
Topics: Anticoagulants; Blood Coagulation Disorders; Chloramphenicol; Coumarins; Drug Interactions; Glucagon; Humans; Models, Biological; Neomycin; Phenylbutazone; Protein Binding; Quinidine; Vitamin K | 1972 |
Phenylbutazone-sodium warfarin binding using a fluorescent probe technique.
Topics: Aniline Compounds; Binding Sites; Binding, Competitive; Fluorescent Dyes; Kinetics; Naphthalenes; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Spectrum Analysis; Sulfonic Acids; Warfarin | 1972 |
Chemical induction of fibrinolysis and inhibition of platelet aggregation (with special respect to effect of nonsteroid antiinflammatory drugs).
Topics: Acetates; Adenosine Diphosphate; Animals; Anti-Inflammatory Agents; Arteriosclerosis; Arthritis, Rheumatoid; Blood Coagulation; Collagen; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ethyl Biscoumacetate; Fibrinolysis; Humans; In Vitro Techniques; Methods; Phenylbutazone; Platelet Adhesiveness; Pyrazoles; Rats; Thrombophlebitis; Warfarin | 1972 |
Effect of pyrazolidine and coumarin derivatives on bleeding time and prothrombin level in rats.
Topics: Adenosine Diphosphate; Administration, Oral; Animals; Anti-Inflammatory Agents; Blood Coagulation; Blood Coagulation Tests; Coumarins; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Ethyl Biscoumacetate; In Vitro Techniques; Injections, Subcutaneous; Phenylbutazone; Platelet Adhesiveness; Prothrombin Time; Pyrazoles; Rabbits; Rats; Warfarin | 1972 |
[Pharmacological interference of glibornuride with sulfaphenazole, phenylbutazone, and phenprocoumon in man].
Topics: Adult; Benzyl Compounds; Blood Glucose; Camphanes; Coumarins; Diabetes Mellitus; Drug Interactions; Half-Life; Humans; Hypoglycemic Agents; Kinetics; Male; Middle Aged; Phenylbutazone; Sulfaphenazole; Sulfonylurea Compounds; Sulfur Isotopes | 1972 |
[Drug incompatibility].
Topics: Absorption; Barbiturates; Coumarins; Drug Incompatibility; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Hydrocortisone; Pharmaceutical Preparations; Phenylbutazone; Smoking | 1973 |
Prothrombin during warfarin treatment.
Topics: Blood Coagulation Disorders; Humans; Immunoelectrophoresis; Myocardial Infarction; Phenylbutazone; Prednisone; Prothrombin; Prothrombin Time; Thrombophlebitis; Time Factors; Warfarin | 1973 |
Effect of phenylbutazone on the binding of vitamin K antagonists to albumin.
Topics: Albumins; Binding Sites; Coumarins; Dialysis; Fluorine; Humans; Phenindione; Phenylbutazone; Protein Binding; Vitamin K; Warfarin | 1973 |
Influence of allopurinol on drug metabolism in man.
Topics: Administration, Oral; Adolescent; Adult; Allopurinol; Drug Interactions; Female; Humans; Male; Middle Aged; Phenylbutazone; Prothrombin Time; Time Factors; Warfarin | 1973 |
Antiinflammatory activity of the new mould metabolite 11-desacetoxy-wortmannin and of some of its derivatives.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Carrageenan; Coumarins; Dexamethasone; Edema; Freund's Adjuvant; Granuloma; Indenes; Indomethacin; Penicillium; Phenylbutazone; Rats | 1974 |
Binding of basic and acidic drugs to rat tissue subcellular fractions.
Topics: Animals; Binding Sites; Brain; Cell Nucleus; Chlorpromazine; Imipramine; Kidney; Kinetics; Liver; Lung; Male; Methadone; Microsomes; Mitochondria; Muscles; Organ Specificity; Phenylbutazone; Protein Binding; Rats; Receptors, Drug; Salicylates; Sulfadimethoxine; Warfarin | 1974 |
Warfarin. Stereochemical aspects of its metabolism and the interaction with phenylbutazone.
Topics: Blood Coagulation; Chromatography, Thin Layer; Drug Interactions; Humans; Metabolic Clearance Rate; Oxidation-Reduction; Phenylbutazone; Protein Binding; Prothrombin Time; Stereoisomerism; Warfarin | 1974 |
Binding of certain acidic drugs to human albumin: theoretical and practical estimation of fundamental parameters.
Topics: Acenocoumarol; Binding Sites; Butyrates; Carbon Radioisotopes; Dialysis; Humans; Kinetics; Mathematics; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Serum Albumin; Ultrafiltration; Warfarin | 1974 |
Drug interactions.
Topics: 1-Propanol; Acute Kidney Injury; Aged; Albumins; Antidepressive Agents; Antihypertensive Agents; Benzyl Compounds; Cephaloridine; Coumarins; Digitoxin; Diuretics; Drug Interactions; Ethacrynic Acid; Guanethidine; Guanidines; Heart; Heart Block; Heart Conduction System; Humans; Hypoglycemia; Hypotension; Kidney; Pancreas; Phenylbutazone; Salicylates; Sympathetic Nervous System; Tolbutamide; Warfarin | 1974 |
[Affecting the blood sugar lowering action of oral antidiabetics by other drugs and renal insufficiency].
Topics: Blood Glucose; Carbohydrate Metabolism; Chloramphenicol; Contraceptives, Oral; Coumarins; Diabetes Complications; Diabetic Nephropathies; Drug Synergism; Female; Glucose Tolerance Test; Humans; Hypoglycemia; Hypoglycemic Agents; Phenylbutazone; Pyrimidines; Sulfonic Acids | 1970 |
Determination of phenylbutazone in plasma.
Topics: Animals; Injections, Intravenous; Male; Methods; Oxidation-Reduction; Phenobarbital; Phenylbutazone; Phenytoin; Potassium Permanganate; Rats; Salicylates; Spectrophotometry; Spectrum Analysis; Sulfadiazine; Time Factors; Ultraviolet Rays; Warfarin | 1972 |
Non-equivalent preparations of the same drug.
Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin | 1971 |
Numerical solution of nonlinear pharmacokinetic equations: effects of plasma protein binding on drug distribution and elimination.
Topics: Aldosterone; Binding Sites; Blood Proteins; Kinetics; Models, Biological; Phenylbutazone; Protein Binding; Thyroxine; Transcortin; Warfarin | 1971 |
Kinetics and clinical importance of displacement of warfarin from albumin by acidic drugs.
Topics: Chemical Phenomena; Chemistry; Chloral Hydrate; Computers, Analog; Diazoxide; Drug Synergism; Ethacrynic Acid; Humans; Mathematics; Mefenamic Acid; Nalidixic Acid; Phenylbutazone; Protein Binding; Prothrombin; Prothrombin Time; Serum Albumin; Trichloroacetic Acid; Warfarin | 1971 |
Interactions between digitoxin and other drugs in vitro and in vivo.
Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin | 1971 |
Pathophysiological factors influencing drug kinetics.
Topics: Absorption; Age Factors; Antipyrine; Chloral Hydrate; Environmental Exposure; Ethanol; Female; Humans; Kinetics; Liver Diseases; Male; Pharmaceutical Preparations; Pharmacogenetics; Phenylbutazone; Pregnancy; Sex Factors; Smoking; Time Factors; Warfarin | 1971 |
Effect of oxygen tension on drug levels and pharmacological action in the intact animal.
Topics: Animals; Barbiturates; Brain Chemistry; Hexobarbital; Hyperbaric Oxygenation; Hypoxia; Isoniazid; Male; Phenylbutazone; Propiophenones; Rats; Sulfadiazine; Warfarin; Zoxazolamine | 1969 |
Studies of the epidemiology of anticoagulant-drug interactions.
Topics: Adult; Anticoagulants; Cholestyramine Resin; Dextrothyroxine; Disulfiram; Drug Antagonism; Drug Synergism; Humans; Phenethylamines; Phenylbutazone; Prothrombin Time; Warfarin | 1970 |
[Influence of liver diseases and kidney function disorders and phenylbutazone, phenprocoumarol and doxycycline on the excretion of glycodiazine].
Topics: Biotransformation; Coumarins; Creatinine; Humans; Hypoglycemic Agents; Kidney Diseases; Liver Diseases; Oxytetracycline; Phenylbutazone; Pyrimidines; Sulfonic Acids | 1970 |
Potentiation of the hypoglycaemic action of tolbutamide by different drugs.
Topics: Animals; Blood Glucose; Coumarins; Drug Synergism; Fasting; Hypoglycemic Agents; Isocarboxazid; Male; Phenylbutazone; Rabbits; Tolbutamide | 1970 |
Pharmacokinetic analysis of potentiating effect of phenylbutazone on anticoagulant action of warfarin in man.
Topics: Adult; Binding Sites; Blood Coagulation; Drug Synergism; Humans; Male; Phenylbutazone; Prothrombin Time; Receptors, Drug; Time Factors; Warfarin | 1970 |
[Interaction, anticoagulants and the risk of bleeding].
Topics: Anticoagulants; Drug Synergism; Hemorrhage; Hemorrhagic Disorders; Humans; Phenylbutazone; Warfarin | 1971 |
The effect of drugs on clinical laboratory determinations.
Topics: 17-Ketosteroids; Chemistry, Clinical; Drug Antagonism; Drug Synergism; Drug Therapy; Hemorrhage; Humans; Nalidixic Acid; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Steroids; Tolbutamide; Urine; Warfarin | 1971 |
[Thromboembolic disease in pregnancy].
Topics: Anticoagulants; Coumarins; Czechoslovakia; Female; Heparin; Humans; Phenylbutazone; Pregnancy; Pregnancy Complications, Cardiovascular; Procaine; Thromboembolism | 1971 |
The displacement of phenylbutazone-14C and warfarin-14C from human albumin by various drugs and fatty acids.
Topics: Benzene Derivatives; Binding Sites; Butyrates; Carbon Isotopes; Chlorine; Dialysis; Fatty Acids, Nonesterified; Humans; Indomethacin; Phenylbutazone; Protein Binding; Serum Albumin; Stearic Acids; Sulfamethoxypyridazine; Tolbutamide; Warfarin | 1968 |
Properties of 3-(1-phenyl-propyl)-4-oxycoumarin (marcoumar) in the plasma when tested in normal cases and under the influence of drugs.
Topics: Blood Proteins; Coumarins; Drug Synergism; Ethyl Biscoumacetate; Fluorometry; Phenobarbital; Phenylbutazone; Protein Binding; Spectrophotometry; Sulfadimethoxine; Sulfinpyrazone; Tolbutamide | 1968 |
Effect of other drugs on oral anticoagulants.
Topics: Acetaminophen; Anticoagulants; Coumarins; Drug Antagonism; Drug Synergism; Heparin; Humans; Oxyphenbutazone; Phenylbutazone; Prothrombin Time; Quinidine; Thromboembolism; Vitamin K; Warfarin | 1969 |
The interaction between cholestyramine and drugs.
Topics: Adsorption; Animals; Aspirin; Bile Acids and Salts; Blood; Chlorothiazide; Cholestyramine Resin; Dogs; Intestinal Absorption; Nicotinic Acids; Phenobarbital; Phenylbutazone; Quinidine; Rats; Spectrophotometry; Tetracycline; Urine; Warfarin | 1965 |
A rare complication of coumarin-congener anticoagulant therapy.
Topics: Blood Coagulation Factors; Coumarins; Hemorrhage; Humans; Phenylbutazone; Prothrombin Time; Purpura, Thrombocytopenic; Vitamin K 1; Warfarin | 1965 |
Potentiation of anticoagulant effect of warfarin by phenylbutazone.
Topics: Adolescent; Adult; Aged; Blood Coagulation; Coronary Disease; Drug Synergism; Humans; Male; Middle Aged; Phenylbutazone; Prothrombin Time; Warfarin | 1967 |
Potentiation of anticoagulants.
Topics: Drug Synergism; Humans; Indomethacin; Male; Middle Aged; Phenylbutazone; Warfarin | 1967 |
The effect of various drugs on the binding of warfarin-14C to human albumin.
Topics: Atropine; Butyrates; Carbon Isotopes; Phenethylamines; Phenylbutazone; Protein Binding; Serum Albumin; Sulfaphenazole; Thyroxine; Warfarin | 1967 |
Drug-binding properties of rat alpha 1-foetoprotein. Binding of warfarin, phenylbutazone, azapropazone, diazepam, digitoxin and cholic acid.
Topics: alpha-Fetoproteins; Animals; Apazone; Binding Sites; Charcoal; Cholic Acid; Cholic Acids; Diazepam; Digitoxin; Phenylbutazone; Protein Binding; Rats; Serum Albumin; Warfarin | 1984 |
Acute upper airway obstruction following sub-lingual haematoma.
Topics: Adult; Airway Obstruction; Drug Synergism; Hematoma; Humans; Male; Mouth Floor; Phenylbutazone; Warfarin | 1983 |
Phenylbutazone-warfarin interaction in man: further stereochemical and metabolic considerations.
Topics: Drug Interactions; Humans; Hydroxylation; Metabolic Clearance Rate; Phenylbutazone; Stereoisomerism; Warfarin | 1983 |
Characterization of an important drug binding area on human serum albumin including the high-affinity binding sites of warfarin and azapropazone.
Topics: Apazone; Binding, Competitive; Dialysis; Diazepam; Glyburide; Humans; Kinetics; Phenylbutazone; Protein Binding; Serum Albumin; Triazines; Warfarin | 1982 |
[Non-steroidal antirheumatics: side-effects and interactions].
Topics: Anemia, Aplastic; Anti-Inflammatory Agents, Non-Steroidal; Coumarins; Drug Interactions; Gastrointestinal Diseases; Humans; Indomethacin; Naproxen; ortho-Aminobenzoates; Phenylbutazone; Prostaglandins; Rheumatic Diseases; Salicylates; Stomach Ulcer | 1982 |
Retention data methods for the determination of drug-protein binding parameters by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Furosemide; Humans; Kinetics; Mathematics; Phenylbutazone; Serum Albumin; Warfarin | 1981 |
Cooperative interaction of warfarin and phenylbutazone with human serum albumin.
Topics: Binding Sites; Binding, Competitive; Humans; In Vitro Techniques; Kinetics; Models, Chemical; Phenylbutazone; Serum Albumin; Warfarin | 1981 |
Comparative interaction of sulfinpyrazone and phenylbutazone with racemic warfarin: alteration in vivo of free fraction of plasma warfarin.
Topics: Adolescent; Adult; Binding Sites; Binding, Competitive; Dialysis; Humans; Male; Phenylbutazone; Stereoisomerism; Sulfinpyrazone; Warfarin | 1981 |
Stereoselective interaction of phenylbutazone with [12C/13C]warfarin pseudoracemates in man.
Topics: Adolescent; Adult; Carbon Isotopes; Drug Interactions; Humans; Hypoprothrombinemias; Kinetics; Male; Phenylbutazone; Prothrombin Time; Stereoisomerism; Warfarin | 1980 |
Comparative pharmacokinetics of coumarin anticoagulants XLV: Pharmacokinetic and pharmacodynamic studies of acute interaction between warfarin and phenylbutazone in rats.
Topics: Animals; Drug Interactions; In Vitro Techniques; Kinetics; Male; Phenylbutazone; Protein Binding; Prothrombin; Rats; Warfarin | 1980 |
Spectrophotofluorometric evidence of negatively cooperative binding of warfarin and phenylbutazone to human serum albumin.
Topics: Binding, Competitive; Humans; Kinetics; Phenylbutazone; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin | 1980 |
Therapeutic rounds at the Milton S. Hershey Medical Center.
Topics: Aged; Cerebral Hemorrhage; Drug Synergism; Female; Humans; Phenylbutazone; Warfarin | 1980 |
Binding of erythromycin base to human plasma proteins.
Topics: Aspirin; Bilirubin; Blood Proteins; Erythromycin; Furosemide; Humans; Hydrogen-Ion Concentration; Orosomucoid; Phenylbutazone; Protein Binding; Serum Albumin; Temperature; Warfarin | 1980 |
Location of binding sites on immobilized human serum albumin for some nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin; Warfarin | 1995 |
Binding of coumarins to site I of human serum albumin. Effect of the fatty acids.
Topics: Biological Transport; Chromans; Coumarins; Fatty Acids; Humans; Ligands; Phenylbutazone; Receptors, Albumin; Serum Albumin; Warfarin | 1995 |
Drug binding properties of glycosylated bovine serum albumin as measured by circular dichroism.
Topics: Binding Sites; Circular Dichroism; Flufenamic Acid; Glycosylation; Ibuprofen; Phenylbutazone; Protein Binding; Serum Albumin, Bovine; Warfarin | 1994 |
Thermodynamic characterization of drug binding to human serum albumin by isothermal titration microcalorimetry.
Topics: Anions; Binding Sites; Calorimetry; Fatty Acids; Humans; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Serum Albumin; Thermodynamics; Warfarin | 1994 |
The use of competitive displacement agents to resolve albumin binding problems observed during the development of a radioimmunoassay for ICI 215001.
Topics: Adrenergic beta-Agonists; Animals; Antibody Specificity; Binding, Competitive; Calibration; Chromatography, Gel; Humans; Hydrogen-Ion Concentration; Phenoxyacetates; Phenylbutazone; Protein Binding; Radioactive Tracers; Radioimmunoassay; Sensitivity and Specificity; Serum Albumin; Sheep; Warfarin | 1994 |
Drug binding properties of glycosylated human serum albumin as measured by fluorescence and circular dichroism.
Topics: Binding Sites; Circular Dichroism; Dansyl Compounds; Flufenamic Acid; Fluorescent Dyes; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Ibuprofen; Phenylbutazone; Proline; Protein Binding; Serum Albumin; Spectrometry, Fluorescence; Warfarin | 1994 |
Study of interaction of carprofen and its enantiomers with human serum albumin--II. Stereoselective site-to-site displacement of carprofen by ibuprofen.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Carbazoles; Circular Dichroism; Dialysis; Humans; Ibuprofen; Mathematics; Models, Chemical; Phenylbutazone; Serum Albumin; Stereoisomerism; Warfarin | 1993 |
Warfarin metabolites: stereochemical aspects of protein binding and displacement by phenylbutazone.
Topics: Humans; In Vitro Techniques; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism; Warfarin | 1993 |
Characterization of site I on human serum albumin: concept about the structure of a drug binding site.
Topics: Acenocoumarol; Anticoagulants; Asparagine; Benzocaine; Binding Sites; Binding, Competitive; Dansyl Compounds; Fluorescent Dyes; Humans; Iodipamide; Phenylbutazone; Serum Albumin; Warfarin | 1996 |
Comparison of drug binding interactions on human, rat and rabbit serum albumin using high-performance displacement chromatography.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzodiazepines; Binding Sites; Binding, Competitive; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Phenylbutazone; Rabbits; Rats; Serum Albumin; Stereoisomerism; Triiodobenzoic Acids; Warfarin | 1995 |
Protein-binding high-performance frontal analysis of (R)- and (S)-warfarin on HSA with and without phenylbutazone.
Topics: Chromatography, High Pressure Liquid; Humans; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism; Warfarin | 1997 |
Improved chromatographic performance of a modified human albumin based stationary phase.
Topics: Binding Sites; Chromatography, Liquid; Ethacrynic Acid; Humans; Indicators and Reagents; Molecular Conformation; Phenylbutazone; Serum Albumin; Silicon Dioxide; Warfarin | 1997 |
Species differences of serum albumins: I. Drug binding sites.
Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Humans; Ibuprofen; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Rabbits; Rats; Serum Albumin; Warfarin | 1997 |
Species differences of serum albumins: III. Analysis of structural characteristics and ligand binding properties during N-B transitions.
Topics: Animals; Binding Sites; Cattle; Diazepam; Dogs; Histidine; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ligands; Phenylbutazone; Protein Conformation; Rabbits; Rats; Serum Albumin; Serum Albumin, Bovine; Species Specificity; Warfarin | 1998 |
Vacancy affinity capillary electrophoresis to study competitive protein-drug binding.
Topics: Animals; Binding, Competitive; Cattle; Electrophoresis, Capillary; Evaluation Studies as Topic; Furosemide; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Serum Albumin; Warfarin | 1998 |
Interaction between two dicarboxylate endogenous substances, bilirubin and an uremic toxin, 3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid, on human serum albumin.
Topics: Bilirubin; Binding Sites; Binding, Competitive; Dicarboxylic Acids; Furans; Humans; Hydrogen-Ion Concentration; Ligands; Phenylbutazone; Propionates; Protein Conformation; Serum Albumin; Warfarin | 1999 |
Identification and reactivity of the major metabolite (beta-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplastic Agents; Chromatography, High Pressure Liquid; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Gas Chromatography-Mass Spectrometry; Glucuronidase; Glucuronides; Humans; Hydrogen-Ion Concentration; Hydrolysis; Male; Mice; Mice, Inbred C57BL; Models, Chemical; Phenylbutazone; Protein Binding; Rabbits; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Time Factors; Warfarin; Xanthenes; Xanthones | 2001 |
Drug-plasma protein binding assay by electrokinetic chromatography-frontal analysis.
Topics: beta-Cyclodextrins; Blood Proteins; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Diclofenac; Electrophoresis, Capillary; Humans; Ketoprofen; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Serum Albumin; Sulfathiazole; Sulfathiazoles; Warfarin | 2002 |
Molecular basis of sulindac competition with specific markers for the major binding sites on human serum albumin.
Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; Biomarkers; Chromatography, High Pressure Liquid; Diazepam; Humans; Kinetics; Phenylbutazone; Serum Albumin; Sulindac; Temperature; Thermodynamics; Warfarin | 2003 |
[Prevention of complications during therapy of thromboses and myocardial infarct with anticoagulants (heparin, coumarin) by successful administration of butazolidin].
Topics: Anticoagulants; Coumarins; Embolism; Heparin; Humans; Myocardial Infarction; Phenylbutazone; Thrombosis | 1957 |
[Experience with butazolidin-sintrom combined prevention & butazolidine prevention Of thromboembolic disease].
Topics: Acenocoumarol; Anticoagulants; Coumarins; Phenylbutazone; Thromboembolism | 1958 |
[The use of butazolidin associated with anticoagulants].
Topics: Anticoagulants; Coumarins; Humans; Phenylbutazone; Thromboembolism | 1961 |
POTENTIATION OF ANTICOAGULANTS CAUSED BY PYRAZOLE COMPOUNDS.
Topics: Anticoagulants; Blood Chemical Analysis; Chemical Phenomena; Chemistry; Coronary Disease; Gout; Hematuria; Humans; Oxyphenbutazone; Phenylbutazone; Pyrazoles; Toxicology; Uric Acid; Warfarin | 1964 |
[PAROXYSMAL NOCTURNAL HEMOGLOBINURIA, ASSOCIATED WITH BECHTEREW'S DISEASE. CASE REPORT AND THERAPEUTIC OBSERVATIONS].
Topics: Ankylosis; Coumarins; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Humans; Phenylbutazone; Prednisone; Spondylitis; Spondylitis, Ankylosing | 1964 |
COMBINED EFFECT OF SODIUM WARFARIN AND PHENYLBUTAZONE.
Topics: Arthritis; Coronary Disease; Geriatrics; Hemorrhage; Oxyphenbutazone; Phenylbutazone; Prothrombin Time; Rheumatic Heart Disease; Sodium; Toxicology; Warfarin | 1964 |
[ACTION OF A HEPARINOID IN ARTERIOSCLEROTICS UNDER ANTICOAGULANT THROMBOLYTIC TREATMENT].
Topics: Anticoagulants; Arteriosclerosis; Cholesterol; Choline; Coumarins; Heparinoids; Humans; Lipids; Lipoproteins; Methionine; Phenylbutazone; Toxicology; Vasodilator Agents | 1963 |
Evaluation of the protein binding ratio of drugs by a micro-scale ultracentrifugation method.
Topics: Adult; Albumins; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Chromatography, Liquid; Computer Simulation; Electrophoresis, Polyacrylamide Gel; Humans; Kinetics; Male; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Silver Staining; Spectrometry, Mass, Electrospray Ionization; Ultracentrifugation; Warfarin | 2004 |
Protein binding characteristics of 2'-benzoyloxycinnamaldehyde.
Topics: Acrolein; Anti-Inflammatory Agents, Non-Steroidal; Anticoagulants; Antineoplastic Agents; Benzoates; Diazepam; Dose-Response Relationship, Drug; GABA Modulators; Humans; Immunoglobulin G; Kinetics; Orosomucoid; Phenylbutazone; Protein Binding; Serum Albumin; Temperature; Warfarin | 2005 |
Determination of drug-serum protein interactions via fluorescence polarization measurements.
Topics: Blood Proteins; Chemistry Techniques, Analytical; Chemistry, Pharmaceutical; Chlorpromazine; Dipyridamole; Fluorescence Polarization; Fluorescent Dyes; gamma-Aminobutyric Acid; Humans; Naproxen; Orosomucoid; Phenylbutazone; Salicylic Acid; Serum Albumin; Warfarin | 2007 |
Rapid characterization of drug-drug interaction in plasma protein binding using a surface plasmon resonance biosensor.
Topics: Binding Sites; Biosensing Techniques; Blood Proteins; Drug Interactions; Humans; Naproxen; Phenylbutazone; Protein Binding; Surface Plasmon Resonance; Warfarin | 2008 |
Amino acid positions 69-132 of UGT1A9 are involved in the C-glucuronidation of phenylbutazone.
Topics: Amino Acids; Catalysis; Coumarins; DNA Primers; Glucuronosyltransferase; Humans; Kinetics; Models, Biological; Phenylbutazone; Protein Isoforms; Recombinant Fusion Proteins; UDP-Glucuronosyltransferase 1A9 | 2008 |
Mechanism for potentiation of warfarin by phenylbutazone. Inhibition of vitamin K-dependent carboxylation and prothrombin synthesis by phenylbutazone in preparations from rat liver.
Topics: Animals; Anticoagulants; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Synergism; Female; Liver; Metabolic Clearance Rate; Microsomes, Liver; Phenylbutazone; Prothrombin; Rats; Rats, Sprague-Dawley; Time Factors; Vitamin K; Vitamins; Warfarin | 1981 |
Biomolecular interaction mechanism of an anticancer drug, pazopanib with human serum albumin: a multi-spectroscopic and computational approach.
Topics: Antineoplastic Agents; Binding Sites; Circular Dichroism; Diazepam; Humans; Indazoles; Molecular Docking Simulation; Phenylbutazone; Protein Binding; Protein Kinase Inhibitors; Pyrimidines; Serum Albumin, Human; Spectrometry, Fluorescence; Sulfonamides; Thermodynamics; Warfarin | 2022 |