phenylbutazone and tolbutamide

phenylbutazone has been researched along with tolbutamide in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199054 (77.14)18.7374
1990's3 (4.29)18.2507
2000's3 (4.29)29.6817
2010's8 (11.43)24.3611
2020's2 (2.86)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Buttar, D; Colclough, N; Gerhardt, S; MacFaul, PA; Maskos, K; Phillips, SD; Plowright, A; Steinbacher, S; Steuber, H; Tam, K; Whittamore, P1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Prandota, J; Pruitt, AW1
Gugler, R1
Gachályi, B; Káldor, A; Szita, M; Tornyossy, M2
Christensen, LK; Hansen, JM1
Kapoor, A; Veronich, K; White, G1
El-Denshary, EE; Montague, W1
Brown, KF; Crooks, MJ1
Meffin, PJ; Rowland, M; Weinkam, RJ1
Ackermann, E1
Birkett, DJ; Pond, SM; Wade, DN1
Assandri, A; Perazzi, A1
Braun, W; Koslowski, H; Menzel, K1
Hage, DS; Noctor, TA; Wainer, IW1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y1
Ocran, K; Owusu, SK1
Coppi, G; Perego, R; Vanoni, PC; Vidi, A1
Göres, E; Kiesewetter, R1
Welch, RM1
Meyer, FP; Walther, H1
Hellman, B1
Sellers, E; Weser, JK1
Wosilait, WD1
Eipe, J1
Black, M1
Anderson, LG; Soeldner, JS; Tannenbaum, H1
MacLennan, WJ1
Ober, KF1
Street, JC1
Burns, JJ; Harrison, YE; Welch, RM1
Ito, S1
Ichibagase, H; Inoue, K; Kojima, S; Suenaga, A1
Martin, FI; Stocks, AE1
Kocialski, AB; Malone, MH; Marozzi, FJ1
Böttiger, LE; Westerholm, B1
Abrams, WB; Reich, S; Solomon, HM; Spirt, N1
Abdel-Maguid, R; el-Dakhakhny, M; Mahfouz, M1
Flessa, HC; Sigell, LT1
Calhoun, FJ; Schrogie, JJ; Tolson, WW1
Brody, BB1
Königstein, RP1
Schrogie, JJ; Solomon, HM; Williams, D1
Duckert, F; Seiler, K1
Airth, JM; Bray, DF; Radecka, C1
Iosefa, RN; Slade, IH1
Gylfe, E; Hellman, B; Sehlin, J; Täljedal, B1
Diwan, PV; Kulkarni, DR1
Goldberg, DM1
Feron, VJ; Groene, EM; Horbach, GJ; Kappers, WA; Kleij, LA; Witkamp, RF; Zweers-Zeilmaker, WM1
Horbach, GJ; Witkamp, RF; Zweers-Zeilmaker, WM1
GULBRANDSEN, R1
CHRISTENSEN, LK; HANSEN, JM; KRISTENSEN, M1
MERKER, HJ; REMMER, H1
ERSLEV, AJ1
BURNS, JJ1
KUNIN, CM1
Califf, RM; Demets, D; George, JT; Gerstein, HC; Granger, C; Green, JB; Hobbs, T; Holman, RR; Lawson, FC; Leiter, LA; McGuire, DK; McMurray, J; Pagidipati, NJ; Pfeffer, MA; Reusch, J; Riesmeyer, JS; Roe, MT; Rosenberg, Y; Sharma, A; Temple, R; Wiviott, S1
Glatz, Z; Michalcová, L; Nevídalová, H1

Reviews

11 review(s) available for phenylbutazone and tolbutamide

ArticleYear
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
    Drugs, 1977, Volume: 13, Issue:1

    Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide

1977
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats.
    Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5

    Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin

1985
[Protein binding of biologically active substances and the therapeutic significance of its modification].
    Zeitschrift fur arztliche Fortbildung, 1974, Jul-15, Volume: 68, Issue:14

    Topics: Age Factors; Anti-Inflammatory Agents; Bilirubin; Blood Proteins; Drug Therapy; Fatty Acids, Nonesterified; Humans; Insulin; Kinetics; Penicillins; Phenylbutazone; Protein Binding; Sulfanilamides; Thyroid Function Tests; Thyroxine-Binding Proteins; Tolbutamide

1974
Drug interactions with coumarin anticoagulants. 2.
    The New England journal of medicine, 1971, Sep-02, Volume: 285, Issue:10

    Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide

1971
Drugs affecting therapy with anticoagulants.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Estrogens; Ethanol; Heparin; Humans; Hypnotics and Sedatives; Phenylbutazone; Phenytoin; Salicylates; Thyroxine; Tolbutamide; Vitamin K

1972
Liver disease and drug therapy.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Amobarbital; Azathioprine; Half-Life; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Metabolic Clearance Rate; Niridazole; Pentobarbital; Pharmaceutical Preparations; Phenylbutazone; Prednisone; Schistosomiasis; Sulfur Radioisotopes; Tolbutamide

1974
VI. Biochemical and pathological effects. Organochlorine insecticides and the stimulation of liver microsome enzymes.
    Annals of the New York Academy of Sciences, 1969, Volume: 160, Issue:1

    Topics: Adipose Tissue; Aminopyrine; Animals; Barbiturates; Benzopyrenes; Carbon Isotopes; Chlordan; DDT; Dichlorodiphenyldichloroethane; Dieldrin; Enzyme Induction; Female; Insecticides; Liver; Male; Methylcholanthrene; Microsomes; Phenylbutazone; Rats; Tolbutamide

1969
[Recent data on thyroxine-binding protein].
    Saishin igaku. Modern medicine, 1967, Volume: 22, Issue:7

    Topics: Androgens; Animals; Anticoagulants; Barbiturates; Bilirubin; Carbon Dioxide; Chemical Phenomena; Chemistry, Physical; Diuretics; Estrogens; Glucocorticoids; Humans; Novobiocin; Penicillins; Phenylbutazone; Phenytoin; Salicylates; Thyroid Diseases; Thyroxine; Thyroxine-Binding Proteins; Tolbutamide

1967
Interaction of sulfonylurea with the pancreatic B-cell.
    Experientia, 1984, Oct-15, Volume: 40, Issue:10

    Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Adenosine Triphosphate; Amino Acids; Animals; Calcimycin; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Fatty Acids; Glucose; Glyburide; Humans; Islets of Langerhans; Lasalocid; Membrane Potentials; NADP; Phenylbutazone; Rubidium; Serum Albumin; Sulfonylurea Compounds; Time Factors; Tolbutamide

1984
The expanding role of microsomal enzyme induction, and its implications for clinical chemistry.
    Clinical chemistry, 1980, Volume: 26, Issue:6

    Topics: Acetaminophen; Alcoholism; Animals; Antipyrine; Aryl Hydrocarbon Hydroxylases; Electron Transport; Energy Intake; Enzyme Induction; Epilepsy; Female; Humans; Male; Microsomes, Liver; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Smoking; Tolbutamide; Warfarin

1980
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Trials

1 trial(s) available for phenylbutazone and tolbutamide

ArticleYear
[Interaction of phenylbutazone and tolbutamide in man].
    Orvosi hetilap, 1979, Nov-25, Volume: 120, Issue:47

    Topics: Clinical Trials as Topic; Drug Interactions; Half-Life; Humans; Phenylbutazone; Tolbutamide

1979

Other Studies

58 other study(ies) available for phenylbutazone and tolbutamide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions.
    Bioorganic & medicinal chemistry, 2010, Nov-01, Volume: 18, Issue:21

    Topics: Binding Sites; Crystallography, X-Ray; Drug Interactions; Humans; Pharmaceutical Preparations; Protein Binding; Protein Structure, Tertiary; Serum Albumin; Spectrometry, Fluorescence

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Furosemide binding to human albumin and plasma of nephrotic children.
    Clinical pharmacology and therapeutics, 1975, Volume: 17, Issue:2

    Topics: Acetazolamide; Aspirin; Child; Diazoxide; Dose-Response Relationship, Drug; Female; Furosemide; Humans; Hydrogen-Ion Concentration; Male; Nephrotic Syndrome; Phenylbutazone; Phosphates; Protein Binding; Renal Dialysis; Serum Albumin; Sulfisoxazole; Temperature; Time Factors; Tolbutamide

1975
[Drug interactions in therapy using coumarin derivatives].
    Der Internist, 1979, Volume: 20, Issue:5

    Topics: Allopurinol; Anti-Inflammatory Agents; Barbiturates; Biological Availability; Cholestyramine Resin; Coumarins; Drug Interactions; Humans; Metronidazole; Phenylbutazone; Rifampin; Sulfonamides; Tolbutamide

1979
Effects of phenylbutazone, tolbutamide, and clofibric acid on binding of racemic warfarin and its enantiomers to human serum albumin.
    Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:12

    Topics: Binding, Competitive; Clofibrate; Clofibric Acid; Humans; Kinetics; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism; Tolbutamide; Warfarin

1979
Effects of drugs on glucose and tolbutamide-stimulated insulin release from isolated rat islets of Langerhans.
    Biochemical pharmacology, 1976, Jul-01, Volume: 25, Issue:13

    Topics: Animals; Chlorpromazine; Female; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Phenylbutazone; Rats; Salicylates; Stimulation, Chemical; Tolbutamide

1976
Displacement of tolbutamide, glibencalmide and chlorpropamide from serum albumin by anionic drugs.
    Biochemical pharmacology, 1976, May-15, Volume: 25, Issue:10

    Topics: Acetaminophen; Animals; Cattle; Chlorpropamide; Dialysis; Glyburide; Humans; Phenylbutazone; Protein Binding; Salicylates; Serum Albumin; Serum Albumin, Bovine; Sulfaphenazole; Tolbutamide; Warfarin

1976
Determination of phenylbutazone, tolbutamide and metabolites in plasma and urine using chemical ionization mass spectrometry.
    Biomedical mass spectrometry, 1977, Volume: 4, Issue:1

    Topics: Animals; Drug Interactions; Mass Spectrometry; Phenylbutazone; Sheep; Tolbutamide

1977
[Pharmacokinetics in liver cirrhosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jan-01, Volume: 32, Issue:1

    Topics: Aminopyrine; Biotransformation; Chloramphenicol; Coumarins; Half-Life; Humans; Kinetics; Liver Cirrhosis; Pharmaceutical Preparations; Phenylbutazone; Salicylates; Tolbutamide

1977
Mechanisms of inhibition of tolbutamide metabolism: phenylbutazone, oxyphenbutazone, sulfaphenazole.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:5 Pt 1

    Topics: Adult; Depression, Chemical; Drug Interactions; Half-Life; Humans; Male; Oxyphenbutazone; Phenylbutazone; Sulfaphenazole; Time Factors; Tolbutamide

1977
Competition between diftalone and other drugs for the binding site(s) on human serum albumin.
    Medical biology, 1976, Volume: 54, Issue:3

    Topics: Acetaminophen; Aspirin; Binding Sites; Dexamethasone; Drug Interactions; Humans; Indomethacin; Phenobarbital; Phenylbutazone; Phthalazines; Protein Binding; Pyridazines; Serum Albumin; Temperature; Tolbutamide; Warfarin

1976
[In-vitro studies on the effect of drugs on albumin-bilirubin binding].
    Kinderarztliche Praxis, 1975, Volume: 43, Issue:2

    Topics: Ampicillin; Bilirubin; Humans; In Vitro Techniques; Orotic Acid; Phenobarbital; Phenylbutazone; Protein Binding; Serum Albumin; Sulfamethoxypyridazine; Sulfathiazoles; Tolbutamide

1975
Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by high-performance liquid affinity chromatography, on a human serum albumin-based stationary phase.
    Journal of chromatography, 1992, Jun-10, Volume: 577, Issue:2

    Topics: Allosteric Site; Binding, Competitive; Caprylates; Chromatography, High Pressure Liquid; Humans; Ketoprofen; Oxazepam; Pharmaceutical Preparations; Phenylbutazone; Serum Albumin; Stereoisomerism; Suprofen; Tolbutamide; Warfarin

1992
Paradoxical behaviour of phenylbutazone in African diabetics.
    Lancet (London, England), 1972, Feb-19, Volume: 1, Issue:7747

    Topics: Adult; Africa; Diabetes Mellitus; Drug Antagonism; Female; Humans; Liver; Male; Middle Aged; Phenylbutazone; Racial Groups; Tolbutamide

1972
Biochemical investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 3. Enzyme induction and interaction with other drugs in the rat.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Barbiturates; Blood Glucose; Dicumarol; Drug Interactions; Enzyme Induction; Ethyl Biscoumacetate; Female; Hypoglycemic Agents; Phenylbutazone; Prothrombin Time; Pyrazoles; Rats; Terpenes; Time Factors; Tolbutamide

1972
[Dangers in drug combinations].
    Zeitschrift fur arztliche Fortbildung, 1972, Feb-15, Volume: 66, Issue:4

    Topics: Dicumarol; Dosage Forms; Drug Antagonism; Drug Interactions; Drug Synergism; Erythroblastosis, Fetal; Female; Humans; Isocarboxazid; Microsomes, Liver; Phenylbutazone; Pregnancy; Sulfaphenazole; Sulfonamides; Tolbutamide

1972
Drug-protein binding: a method for studying the interactions of drugs with bishydroxycoumarin (dicoumarol) in dogs.
    Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226

    Topics: Allopurinol; Animals; Antipyrine; Blood Coagulation; Dicumarol; Dogs; Drug Interactions; Drug Synergism; Enzyme Induction; Half-Life; Liver; Methods; Oxidoreductases; Phenobarbital; Phenylbutazone; Protein Binding; Prothrombin Time; Time Factors; Tolbutamide

1973
Potentiating effects of drugs on the binding of glibenclamide to pancreatic beta cells.
    Metabolism: clinical and experimental, 1974, Volume: 23, Issue:9

    Topics: Animals; Binding Sites; Drug Synergism; Female; Glyburide; Hyperglycemia; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Phenylbutazone; Serum Albumin; Sucrose; Sulfaphenazole; Sulfisomidine; Sulfisoxazole; Sulfonamides; Tolbutamide

1974
An analysis of the effect of hypoalbuminemia on the amount of free drug in plasma for drugs bound at two sets of sites.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 9, Issue:4

    Topics: Binding Sites; Carbenoxolone; Chlorpromazine; Chlorpropamide; Computers; Dose-Response Relationship, Drug; Humans; Iopanoic Acid; Pharmaceutical Preparations; Phenylbutazone; Protein Binding; Quinidine; Salicylates; Serum Albumin; Sulfadiazine; Tolbutamide

1974
Letter: Phenylbutazone-tolbutamide drug interaction.
    The New England journal of medicine, 1974, Feb-07, Volume: 290, Issue:6

    Topics: Drug Synergism; Humans; Hypoglycemia; Male; Middle Aged; Phenylbutazone; Tolbutamide

1974
Drug interactions.
    Gerontologia clinica, 1974, Volume: 16, Issue:1

    Topics: 1-Propanol; Acute Kidney Injury; Aged; Albumins; Antidepressive Agents; Antihypertensive Agents; Benzyl Compounds; Cephaloridine; Coumarins; Digitoxin; Diuretics; Drug Interactions; Ethacrynic Acid; Guanethidine; Guanidines; Heart; Heart Block; Heart Conduction System; Humans; Hypoglycemia; Hypotension; Kidney; Pancreas; Phenylbutazone; Salicylates; Sympathetic Nervous System; Tolbutamide; Warfarin

1974
Mechanism of interaction of tolbutamide and phenylbutazone in diabetic patients.
    European journal of clinical pharmacology, 1974, Jul-26, Volume: 7, Issue:4

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Drug Interactions; Drug Therapy, Combination; Female; Humans; Middle Aged; Phenylbutazone; Tolbutamide

1974
Implications of enzyme induction in drug toxicity studies.
    Toxicology and applied pharmacology, 1967, Volume: 10, Issue:2

    Topics: Animals; Antipyrine; Diphenhydramine; Dogs; Enzyme Induction; Female; Haplorhini; Liver; Male; Microsomes; Peptic Ulcer; Phenylbutazone; Probenecid; Rats; Tolbutamide

1967
Studies on synthetic sweetening agents. XV. Metabolism of sodium cyclamate. Influences of phenylbutaone, phenobarbital, and tolbutamide on metabolism of sodium cyclamate in rabbits.
    Chemical & pharmaceutical bulletin, 1972, Volume: 20, Issue:1

    Topics: Animals; Cyclamates; Cyclohexanecarboxylic Acids; Cyclohexylamines; In Vitro Techniques; Liver; Male; Phenobarbital; Phenylbutazone; Rabbits; Sodium; Stimulation, Chemical; Tolbutamide

1972
Hypoglycaemia due to erroneous drug ingestion.
    The Medical journal of Australia, 1972, Jun-10, Volume: 1, Issue:24

    Topics: Adult; Chlorpropamide; Glucose Tolerance Test; Humans; Hypoglycemia; Insulin; Male; Medication Errors; Phenylbutazone; Tolbutamide

1972
Effects of certain nonsteroid anti-inflammatory drugs, tolbutamide, and tetrahydroalstonine on blood glucose and carrageen in-induced pedal edema in rats.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:8

    Topics: Alkaloids; Animals; Anti-Inflammatory Agents; Blood Glucose; Carrageenan; Chlorpromazine; Diabetes Mellitus, Experimental; Edema; Foot; Indoles; Indomethacin; Male; Phenylbutazone; Plant Extracts; Plethysmography; Protamines; Quinolizines; Rats; Rats, Inbred Strains; Secologanin Tryptamine Alkaloids; Semicarbazides; Tetrabenazine; Tolbutamide; Zinc

1972
Aplastic anaemia. I. Incidence and aetiology.
    Acta medica Scandinavica, 1972, Volume: 192, Issue:4

    Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Child; Child, Preschool; Chloramphenicol; Female; Humans; Male; Middle Aged; Oxyphenbutazone; Phenylbutazone; Sweden; Tolbutamide

1972
Non-equivalent preparations of the same drug.
    Drug and therapeutics bulletin, 1971, Aug-13, Volume: 9, Issue:17

    Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin

1971
Interactions between digitoxin and other drugs in vitro and in vivo.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin

1971
Potentiation of the hypoglycaemic action of tolbutamide by different drugs.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:1

    Topics: Animals; Blood Glucose; Coumarins; Drug Synergism; Fasting; Hypoglycemic Agents; Isocarboxazid; Male; Phenylbutazone; Rabbits; Tolbutamide

1970
Drug interactions with anticoagulants.
    JAMA, 1970, Dec-14, Volume: 214, Issue:11

    Topics: Acetaminophen; Animals; Anti-Bacterial Agents; Anticoagulants; Ascorbic Acid; Barbiturates; Blood Coagulation; Blood Coagulation Tests; Cardiac Glycosides; Chlordiazepoxide; Chlorothiazide; Contraceptives, Oral; Diazepam; Dogs; Drug Antagonism; Epinephrine; Ethchlorvynol; Glucagon; Haloperidol; Humans; Methylphenidate; Phenethylamines; Phenylbutazone; Phenytoin; Quinolines; Salicylates; Steroids; Substance-Related Disorders; Tetanus Toxoid; Tolbutamide; Xanthines

1970
Effects of various drugs on the uterotropic response to mestranol and norethynodrel in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1971, Volume: 136, Issue:1

    Topics: Aminosalicylic Acids; Animals; Chlorpromazine; Drug Synergism; Female; Imipramine; Mestranol; Norethynodrel; Organ Size; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Rats; Scopolamine; Tolbutamide; Uterus

1971
The effect of drugs on clinical laboratory determinations.
    Clinical chemistry, 1971, Volume: 17, Issue:5

    Topics: 17-Ketosteroids; Chemistry, Clinical; Drug Antagonism; Drug Synergism; Drug Therapy; Hemorrhage; Humans; Nalidixic Acid; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Steroids; Tolbutamide; Urine; Warfarin

1971
[Iatrogenic diabetes mellitus and some important iatrogenic complications in diabetes].
    Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete, 1967, Volume: 48, Issue:12

    Topics: Aged; Benzothiadiazines; Blood Glucose; Chlorthalidone; Diabetes Complications; Diabetes Mellitus; Diuretics; Female; Furosemide; Glucocorticoids; Humans; Hypoglycemia; Male; Middle Aged; Pancreatectomy; Phenylbutazone; Tolbutamide

1967
The displacement of phenylbutazone-14C and warfarin-14C from human albumin by various drugs and fatty acids.
    Biochemical pharmacology, 1968, Volume: 17, Issue:1

    Topics: Benzene Derivatives; Binding Sites; Butyrates; Carbon Isotopes; Chlorine; Dialysis; Fatty Acids, Nonesterified; Humans; Indomethacin; Phenylbutazone; Protein Binding; Serum Albumin; Stearic Acids; Sulfamethoxypyridazine; Tolbutamide; Warfarin

1968
Properties of 3-(1-phenyl-propyl)-4-oxycoumarin (marcoumar) in the plasma when tested in normal cases and under the influence of drugs.
    Thrombosis et diathesis haemorrhagica, 1968, Jul-31, Volume: 19, Issue:3

    Topics: Blood Proteins; Coumarins; Drug Synergism; Ethyl Biscoumacetate; Fluorometry; Phenobarbital; Phenylbutazone; Protein Binding; Spectrophotometry; Sulfadimethoxine; Sulfinpyrazone; Tolbutamide

1968
Variability of uniformity of weight test as an indicator of the amount of active ingredient in tablets.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:2

    Topics: Chemical Phenomena; Chemistry; Isoniazid; Phenobarbital; Phenylbutazone; Promazine; Tablets; Tolbutamide

1967
Fatal hypoglycemic coma from the use of tolbutamide in elderly patients: report of two cases.
    Journal of the American Geriatrics Society, 1967, Volume: 15, Issue:10

    Topics: Aged; Blood Glucose; Diabetes Mellitus; Drug Synergism; Humans; Hypoglycemia; Insulin Coma; Intracranial Arteriosclerosis; Male; Phenylbutazone; Tolbutamide

1967
Influence of non-steroidal anti-inflammatory agents on tolbutamide hypoglycaemia.
    The Indian journal of medical research, 1983, Volume: 78

    Topics: Animals; Anti-Inflammatory Agents; Female; Humans; Hypoglycemia; Ibuprofen; Indomethacin; Male; ortho-Aminobenzoates; Phenylbutazone; Rabbits; Tolbutamide

1983
Interaction of phenylbutazone and tolbutamide in man.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:9

    Topics: Adult; Drug Interactions; Half-Life; Humans; Middle Aged; Phenylbutazone; Tolbutamide

1980
Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:12

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Gene Expression; Humans; Hydroxylation; Ketoprofen; Lung; Methylation; Mixed Function Oxygenases; Phenylbutazone; Sulfaphenazole; Tolbutamide; Transfection

1996
Differential inhibitory effects of phenytoin, diclofenac, phenylbutazone and a series of sulfonamides on hepatic cytochrome P4502C activity in vitro, and correlation with some molecular descriptors in the dwarf goat (Caprus hircus aegagrus).
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:8

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Enzyme Inhibitors; Female; Goats; Hydroxylation; Kinetics; Liver; Microsomes, Liver; Phenylbutazone; Phenytoin; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Sulfaphenazole; Sulfonamides; Tolbutamide

1997
[Potentiation of tolbutamide by phenylbutazone].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1959, Oct-01, Volume: 79

    Topics: Phenylbutazone; Tolbutamide

1959
SULPHAPHENAZOLE-INDUCED HYPOGLYCAEMIC ATTACKS IN TOLBUTAMIDE-TREATED DIABETICS.
    Lancet (London, England), 1963, Dec-21, Volume: 2, Issue:7321

    Topics: Aged; Diabetes Mellitus; Geriatrics; Humans; Hypoglycemia; Hypoglycemic Agents; Phenylbutazone; Sulfadiazine; Sulfadimethoxine; Sulfaphenazole; Tolbutamide

1963
DRUG-INDUCED CHANGES IN THE LIVER ENDOPLASMIC RETICULUM: ASSOCIATION WITH DRUG-METABOLIZING ENZYMES.
    Science (New York, N.Y.), 1963, Dec-27, Volume: 142, Issue:3600

    Topics: Adenosine Triphosphatases; Animals; Cytochromes; Endoplasmic Reticulum; Liver; Meprobamate; Microscopy, Electron; N-Glycosyl Hydrolases; Nikethamide; Nitrogen; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Phosphoric Monoester Hydrolases; Phosphorus; Tolbutamide

1963
DRUG-INDUCED BLOOD DYSCRASIAS. I. APLASTIC ANEMIA.
    JAMA, 1964, May-11, Volume: 188

    Topics: Acetazolamide; Anemia; Anemia, Aplastic; Anticonvulsants; Benzene; Chloramphenicol; Chlorothiazide; Chlorpropamide; Gold; Hematologic Diseases; Hexachlorocyclohexane; Phenylbutazone; Prednisone; Sulfamethoxypyridazine; Sulfisoxazole; Testosterone; Tolbutamide; Toxicology

1964
INHIBITORS OF PENICILLIN BINDING TO SERUM PROTEINS.
    The Journal of laboratory and clinical medicine, 1965, Volume: 65

    Topics: Acetazolamide; Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antimetabolites; Aspirin; Benzoates; Biguanides; Blood Proteins; Carbon Isotopes; Chlorothiazide; Diuretics; Ethacrynic Acid; Guanidines; Oxazoles; p-Aminohippuric Acid; Penicillin G; Penicillin V; Penicillins; Pharmacology; Phenylbutazone; Probenecid; Rabbits; Research; Salicylates; Sulfinpyrazone; Sulfonamides; Tolbutamide

1965
Impact of Regulatory Guidance on Evaluating Cardiovascular Risk of New Glucose-Lowering Therapies to Treat Type 2 Diabetes Mellitus: Lessons Learned and Future Directions.
    Circulation, 2020, 03-10, Volume: 141, Issue:10

    Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions; Glucose; Glycated Hemoglobin; Glycine; Government Regulation; Humans; Hypoglycemic Agents; Oxazoles; Phenylbutazone; Practice Guidelines as Topic; Risk; Rosiglitazone; Tolbutamide; United States; United States Food and Drug Administration

2020
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin.
    Journal of separation science, 2020, Volume: 43, Issue:22

    Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan

2020