phenylbutazone and suxibuzone

phenylbutazone has been researched along with suxibuzone in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199010 (52.63)18.7374
1990's5 (26.32)18.2507
2000's4 (21.05)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akazawa, A; Kanda, A; Mitani, N; Shindo, T; Taira, K; Yasuda, Y1
Goebel, KM; Hahn, E; Hausmann, L; Kaffarnik, H; Neurath, F; Storck, U1
Erill, S; Laporte, J1
Caturla, MC; Cusido, E1
Debackere, M; Delbeke, FT; Vynckier, L2
Kamiya, T; Konishi, Y; Sakamoto, M; Shibata, K; Takahashi, S; Tsutsumi, M; Yanagi, S1
Honma, M; Kageyama, T; Mizushima, Y; Shiokawa, Y1
Mizushima, Y2
Ishida, N; Kageyama, T; Mitani, N; Oono, F; Shindo, T; Yasuda, Y1
Akazawa, A; Mitani, N; Shindo, T; Taira, K; Yasuda, Y1
Marunaka, T; Minami, Y; Shibata, T; Shindo, T; Umeno, Y1
Gonzalez, F; Jaraiz, V; Rodriguez, C; San Andres, MD; San Andres, MI1
Gonzalez, F; Jaraiz, MV; Rodriguez, C; San Andres, MD; San Andres, MI1
Homedes, J; Mayós, I; Monreal, L; Sabaté, D; Segura, D1
Longhofer, SL; Radecki, SV; Reinemeyer, CR1
Homedes, J; Monreal, L; Sabaté, D; Salichs, M; Sust, M1
Andrews, FM; Longhofer, SL; Reinemeyer, CR1

Trials

6 trial(s) available for phenylbutazone and suxibuzone

ArticleYear
[Current aspects of rheumatoid arthritis].
    Fortschritte der Medizin, 1979, Oct-25, Volume: 97, Issue:40

    Topics: Administration, Oral; Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Drug Tolerance; Female; Humans; Indomethacin; Male; Middle Aged; Phenylbutazone; Time Factors

1979
A double-blind comparison of phenylbutazone and suxibuzone, a prodrug of phenylbutazone, in rheumatoid arthritis.
    International journal of tissue reactions, 1983, Volume: 5, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenylbutazone

1983
Pro-drugs of non-steroidal anti-inflammatory agents.
    European journal of rheumatology and inflammation, 1983, Volume: 6, Issue:2

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Gastrointestinal Diseases; Humans; Indomethacin; Phenylbutazone; Phenylbutyrates; Propionates; Sulindac

1983
Evaluation of the palatability of three nonsteroidal antiinflammatory top-dress formulations in horses.
    Veterinary therapeutics : research in applied veterinary medicine, 2008,Summer, Volume: 9, Issue:2

    Topics: Administration, Oral; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies; Female; Horse Diseases; Horses; Male; Phenylbutazone; Taste

2008
Multicentre, controlled, randomised and blinded field study comparing efficacy of suxibuzone and phenylbutazone in lame horses.
    Equine veterinary journal, 2009, Volume: 41, Issue:7

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Horse Diseases; Horses; Lameness, Animal; Male; Phenylbutazone

2009
Effects of top-dress formulations of suxibuzone and phenylbutazone on development of gastric ulcers in horses.
    Veterinary therapeutics : research in applied veterinary medicine, 2009,Fall, Volume: 10, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Female; Horse Diseases; Horses; Male; Phenylbutazone; Stomach; Stomach Ulcer

2009

Other Studies

13 other study(ies) available for phenylbutazone and suxibuzone

ArticleYear
[The biological fate of 4-butyl-4-(beta-carboxypropionyloxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione(suxibuzone), antiinflammatory drug. I. Plasma levels and urinary excretion after oral administration of suxibuzone (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1979, Volume: 99, Issue:12

    Topics: Administration, Oral; Animals; Dogs; Female; Haplorhini; In Vitro Techniques; Male; Phenylbutazone; Rabbits; Rats; Species Specificity

1979
Uricosuric activity of suxibuzone, a new phenylbutazone derivative.
    Archivos de farmacologia y toxicologia, 1975, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Drug Evaluation; Gout; Humans; Phenylbutazone; Sulfinpyrazone; Uric Acid; Uricosuric Agents

1975
Solid-phase extraction for the high-performance liquid chromatographic determination of indomethacin, suxibuzone, phenylbutazone and oxyphenbutazone in plasma, avoiding degradation of compounds.
    Journal of chromatography, 1992, Oct-02, Volume: 581, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Reproducibility of Results; Spectrophotometry, Ultraviolet

1992
Disposition of human drug preparations in the horse. I. Rectally administered indomethacin.
    Journal of veterinary pharmacology and therapeutics, 1991, Volume: 14, Issue:2

    Topics: Administration, Rectal; Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Doping in Sports; Female; Horses; Hydrolysis; Indomethacin; Phenylbutazone; Reference Standards; Suppositories

1991
Promotion of hepatocarcinogenesis by suxibuzone in rats initiated with 3'-methyl-4-dimethylaminoazobenzene.
    Cancer letters, 1987, Volume: 36, Issue:1

    Topics: Administration, Oral; Animals; Body Weight; Carcinogens; Drug Interactions; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Organ Size; p-Dimethylaminoazobenzene; Phenobarbital; Phenylbutazone; Pyruvate Kinase; Rats; Rats, Inbred Strains

1987
Comparison of the absorption, excretion, and metabolism of suxibuzone and phenylbutazone in humans.
    Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:5

    Topics: Adult; Biotransformation; Feces; Humans; Intestinal Absorption; Kinetics; Male; Phenylbutazone; Time Factors

1982
Basic and clinical studies of prodrugs of nonsteroidal anti-inflammatory drugs.
    Pharmacology, 1982, Volume: 25 Suppl 1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Biotransformation; Humans; Indomethacin; Phenylbutazone; Phenylbutyrates; Propionates; Rats

1982
[The biological fate of 4-butyl-4-(beta-carboxypropionyloxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione (suxibuzone), antiinflammatory drug. II. The biological fate of suxibuzone (SB) after daily oral administration (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1980, Volume: 100, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Dogs; Drug Administration Schedule; Female; Male; Phenylbutazone; Rats

1980
Simultaneous high-performance liquid chromatographic determination of suxibuzone and its metabolites in plasma and urine.
    Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:11

    Topics: Anti-Inflammatory Agents; Chromatography, High Pressure Liquid; Humans; Phenylbutazone

1980
The disposition of suxibuzone in the horse.
    Journal of veterinary pharmacology and therapeutics, 1993, Volume: 16, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Proteins; Chromatography, High Pressure Liquid; Female; Half-Life; Horses; Injections, Intravenous; Liver; Oxyphenbutazone; Phenylbutazone; Protein Binding

1993
Pharmacokinetics and bioequivalence of two suxibuzone oral dosage forms in horses.
    Journal of veterinary pharmacology and therapeutics, 1999, Volume: 22, Issue:4

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Chromatography, High Pressure Liquid; Cross-Over Studies; Dosage Forms; Horses; Male; Phenylbutazone; Therapeutic Equivalency

1999
Disposition and tolerance of suxibuzone in horses.
    Equine veterinary journal, 1999, Volume: 31, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Blood Cell Count; Chromatography, High Pressure Liquid; Hematocrit; Horses; Indomethacin; Injections, Intravenous; Male; Oxyphenbutazone; Phenylbutazone; Synovial Fluid

1999
Lower gastric ulcerogenic effect of suxibuzone compared to phenylbutazone when administered orally to horses.
    Research in veterinary science, 2004, Volume: 76, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Gastric Mucosa; Horse Diseases; Horses; Male; Phenylbutazone; Stomach Ulcer

2004