phenylbutazone has been researched along with methotrexate in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (68.29) | 18.7374 |
| 1990's | 1 (2.44) | 18.2507 |
| 2000's | 7 (17.07) | 29.6817 |
| 2010's | 5 (12.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Cha, SH; Endou, H; Hosoyamada, M; Khamdang, S; Kimura, H; Narikawa, S; Sekine, T; Takeda, M | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Flenker, I; Ricken, D | 1 |
| Moen, F | 1 |
| Kitchen, EA; Meacock, SC | 1 |
| Adams, JD; Hunter, GA | 1 |
| Glette, J; Haneberg, B; Solberg, CO; Sørnes, S | 1 |
| Beck, FJ; Levy, L; Whitehouse, MW | 1 |
| Bouletreau, P; Ducluzeau, R | 1 |
| Kölle, G | 1 |
| Diem, E; Oppolzer, R | 1 |
| Rubinstein, H; Szanto, M | 1 |
| Colombo, C; Ignarro, LJ | 1 |
| Fossati, C | 1 |
| Jover, A; Levy, A; Migueres, J | 1 |
| Kalbhen, DA; Lynen, J | 1 |
| Dinnendahl, V; Kalbhen, DA; Karzel, K; Katzenberger, K | 1 |
| Karagevrekis, C; Martin, E | 1 |
| Arrigoni-Martelli, E; Restelli, A | 1 |
| Domenjoz, R; Knippertz, T; Mörsdorf, K; Rausch, KD | 1 |
| DiMartino, MJ; Misher, A; Walz, DT | 1 |
| Di Rosa, M; Papadimitriou, JM; Willoughby, DA | 1 |
| Currey, HL | 1 |
| Chinea, G; Colombo, C; Graeme, ML; Piliero, SJ; Sigg, EB | 1 |
| Graeme, ML; John, M; Sigg, EB | 1 |
| Gerber, RC | 1 |
| Hanada, M; Hayashi, J; Imamura, T; Matsuo, T; Matsushita, S; Okamura, H; Tsutsui, K | 1 |
| Calin, A | 1 |
| Azaña, JM; Boixeda, P; de Misa, RF; Harto, A; Ledo, A; Moreno, R | 1 |
| SAMPEY, JR | 1 |
| Cheng, Y; Hu, J; Li, Y; Wu, Q; Xu, T | 1 |
| Cheng, Y; Hu, J; Wu, Q; Xu, T; Zhao, L | 1 |
2 review(s) available for phenylbutazone and methotrexate
| Article | Year |
|---|---|
[Liver damage due to drugs. I].
Topics: Arsenicals; Chemical and Drug Induced Liver Injury; Chloramphenicol; Cholestasis; Coumarins; Drug-Related Side Effects and Adverse Reactions; Erythromycin; Halothane; Humans; Imipramine; Liver; Methotrexate; Methyldopa; Nicotinic Acids; Oxacillin; Phenylbutazone; Testosterone; Tetracycline | 1974 |
NEW AND OLD DRUGS IN THE MANAGEMENT OF HODGKIN'S DISEASE.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Bacterial Agents; Antineoplastic Agents; Cyclophosphamide; Dactinomycin; Dexamethasone; Folic Acid Antagonists; Hodgkin Disease; Humans; Isoniazid; Mannomustine; Melphalan; Methotrexate; Mitomycin; Mitomycins; Nitrogen Mustard Compounds; Phenylbutazone; Prednisolone; Prednisone; Thiotepa | 1964 |
39 other study(ies) available for phenylbutazone and methotrexate
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Characterization of methotrexate transport and its drug interactions with human organic anion transporters.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Cells, Cultured; Humans; Indomethacin; Kinetics; Liver-Specific Organic Anion Transporter 1; Methotrexate; Mice; Mice, Transgenic; Nerve Tissue Proteins; Organic Anion Transporters, Sodium-Independent; Phenylbutazone; Potassium Channels; Potassium Channels, Tandem Pore Domain; Probenecid | 2002 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
[Therapy of systemic lupus erythematosus and of pseudo-le-syndrome].
Topics: Aged; Azathioprine; Chloroquine; Cyclophosphamide; Diagnosis, Differential; Female; Glucocorticoids; Humans; Indomethacin; Lupus Erythematosus, Systemic; Male; Methotrexate; Middle Aged; Phenylbutazone; Prednisone; Salicylates; Sex Factors; Syndrome | 1978 |
[Psoriatic arthropathy].
Topics: Arthritis; Humans; Indomethacin; Methotrexate; Naproxen; Phenylbutazone; Psoriasis | 1977 |
Some effects of non-steroidal anti-inflammatory drugs on leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Carrageenan; Cell Movement; Edema; Fenoprofen; Ibuprofen; Indomethacin; Ketoprofen; Leukocytes; Male; Methotrexate; Naproxen; Phenylbutazone; Pleurisy; Rats | 1976 |
Drug interaction in psoriasis.
Topics: Aged; Drug Interactions; Female; Humans; Male; Methotrexate; Middle Aged; Phenylbutazone; Psoriasis | 1976 |
Influence of fever temperatures and of some cytoactive drugs on in vitro lysozyme release from monocytes and granulocytes.
Topics: Body Temperature; Colchicine; Cyclophosphamide; Dose-Response Relationship, Drug; Fever; Granulocytes; Humans; Hydrocortisone; In Vitro Techniques; Methotrexate; Monocytes; Muramidase; Phenylbutazone | 1985 |
The local graft versus host reaction in the rat as a tool for drug mechanism studies.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Azathioprine; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Graft vs Host Reaction; Immunosuppressive Agents; In Vitro Techniques; Lymphocytes; Lymphoid Tissue; Male; Methotrexate; Organ Size; Phenylbutazone; Radiation Effects; Rats; Spleen; Structure-Activity Relationship; Time Factors; Transplantation Immunology | 1973 |
[Fatal therapeutic complications].
Topics: Adult; Aged; Anesthesia, Local; Anti-Bacterial Agents; Anticoagulants; Blood Group Incompatibility; Cardiac Catheterization; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; Glucocorticoids; Humans; Intubation; Male; Medication Errors; Methotrexate; Middle Aged; Monoamine Oxidase Inhibitors; Phenylbutazone; Tranquilizing Agents; Vaccination; Vinblastine | 1969 |
[Long term therapy of rheumatoid arthritis in children].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis, Juvenile; Azathioprine; Child; Chloroquine; Gold; Humans; Indomethacin; Long-Term Care; Manipulation, Orthopedic; Methotrexate; Phenylbutazone; Physical Therapy Modalities; Pyrazoles; Salicylates; Synovectomy; Uveitis, Anterior | 1970 |
[Reiter's disease].
Topics: Adrenocorticotropic Hormone; Adult; Arthritis, Reactive; Azathioprine; Foot Dermatoses; Hand Dermatoses; Humans; Male; Methotrexate; Phenylbutazone; Skin Manifestations | 1974 |
Reiter's syndrome treated with methotrexate.
Topics: Adult; Arthritis, Reactive; Aspirin; Humans; Male; Methotrexate; Phenylbutazone; Remission, Spontaneous; Tetracycline | 1972 |
Enzyme release from guinea-pig polymorphonuclear leucocyte lysosomes inhibited in vitro by anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Chloroquine; Cyclophosphamide; Depression, Chemical; Flufenamic Acid; Galactosidases; Glucuronidase; Guinea Pigs; Hydrocortisone; In Vitro Techniques; Indomethacin; Leukocytes; Lysosomes; Methotrexate; Phenylbutazone; Sulfatases | 1972 |
[3 years of polychemotherapy of pleuro-pulmonary cancer. Apropos of 95 cases].
Topics: Androgens; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Glucocorticoids; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Mesothelioma; Methotrexate; Phenylbutazone; Pleural Neoplasms; Thiotepa; Vinblastine | 1968 |
[Effect of some anti-inflammatory drugs on the ATP-content and cell proliferation of neoplastic mast cells in vitro].
Topics: Adenosine Triphosphate; Amides; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Benzimidazoles; Benzoates; Cell Division; Chloroquine; Culture Techniques; Depression, Chemical; Dinitrophenols; Indomethacin; Mast-Cell Sarcoma; Methotrexate; Naphthalenes; ortho-Aminobenzoates; Oxyphenbutazone; Phenylbutazone; Salicylamides; Sodium Salicylate; Stimulation, Chemical | 1968 |
[Cell number, cell volume and mitosis rate of synchronized cultures of mastocytoma P-815 and its modification by phenylbutazone and 2,4-dinitrophenol].
Topics: Adenosine Triphosphate; Blood Cell Count; Depression, Chemical; Dinitrophenols; Energy Transfer; Mast-Cell Sarcoma; Methotrexate; Mitosis; Phenylbutazone; Stimulation, Chemical | 1968 |
[The Reiter-Fiessinger-Leroy syndrome. Several autochthonous cases].
Topics: Adrenal Cortex Hormones; Adult; Arthritis, Reactive; Arthritis, Rheumatoid; Diagnosis, Differential; Humans; Male; Methotrexate; Middle Aged; Phenylbutazone; Tetracycline | 1972 |
Release of lysosomal enzymes in experimental inflammations: effects of anti-inflammatory drugs.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspirin; Betamethasone; Carrageenan; Dexamethasone; Edema; Female; Glucuronidase; Hexosaminidases; Indomethacin; Inflammation; Lysosomes; Methotrexate; Nystatin; Phenylbutazone; Prednisolone; Rats; Time Factors | 1972 |
Studies on the antiphlogistic activity of cytostatics.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Carrageenan; Chloramphenicol; Cyclophosphamide; Dextrans; Edema; Fluorouracil; Foot; Hydrolysis; Indomethacin; Inflammation; Leukocyte Count; Male; Methotrexate; Penicillamine; Phenylbutazone; Rats; Triaziquone | 1972 |
Adjuvant-induced arthritis in rats. II. Drug effects on physiologic, biochemical and immunologic parameters.
Topics: Animals; Anti-Inflammatory Agents; Antibodies; Arthritis; Aspirin; Body Weight; Cyclophosphamide; Disease Models, Animal; Freund's Adjuvant; Hindlimb; Immunosuppressive Agents; Indomethacin; Male; Methotrexate; Muramidase; Phenylbutazone; Prednisolone; Rats | 1971 |
A histopathological and pharmacological analysis of the mode of action of nonsteroidal anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Bone Marrow; Carrageenan; Edema; Indomethacin; Leukocytes; Macrophages; Male; Mefenamic Acid; Methotrexate; Phagocytosis; Phenylbutazone; Pleurisy; Radiation Effects; Rats; Thymidine; Tritium; Turpentine | 1971 |
A comparison of immunosuppressive and anti-inflammatory agents in the rat.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Antilymphocyte Serum; Arthritis; Azathioprine; Chlorambucil; Cyclophosphamide; Erythrocytes; Female; Freund's Adjuvant; Hindlimb; Hydrocortisone; Hypersensitivity, Delayed; Immunosuppressive Agents; Inflammation; Male; Methotrexate; Phenylbutazone; Rats; Sheep; Tuberculin Test | 1971 |
Action of anti-inflammatory agents upon blood and histopathologic changes induced by periarthritis in rats.
Topics: Adrenal Glands; Animals; Blood Cell Count; Blood Protein Electrophoresis; Blood Sedimentation; Chlorpromazine; Fibrinogen; Indomethacin; Male; Mercaptopurine; Methotrexate; Organ Size; Oxyphenbutazone; Paramethasone; Phenylbutazone; Rats; Spleen; Streptomycin; Thymus Gland | 1966 |
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats.
Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides | 1967 |
Diagnosis and management of Reiter's syndrome.
Topics: Adult; Anti-Inflammatory Agents; Arthritis, Reactive; Azathioprine; Child; Diagnosis, Differential; Female; HLA Antigens; HLA-B27 Antigen; Humans; Indomethacin; Male; Methotrexate; Phenylbutazone; Prognosis | 1984 |
[Reiter's disease associated with paroxysmal nocturnal hemoglobinuria].
Topics: Adult; Arthritis, Reactive; Hemoglobinuria, Paroxysmal; Humans; Male; Methotrexate; Phenylbutazone | 1983 |
Reiter's syndrome--1982.
Topics: Arthritis, Reactive; Azathioprine; Female; HLA Antigens; HLA-B27 Antigen; Humans; Indomethacin; Male; Methotrexate; Phenylbutazone | 1982 |
Psoriatic arthritis: one year of treatment with extracorporeal photochemotherapy.
Topics: Adult; Arthritis, Psoriatic; Etretinate; Humans; Indomethacin; Male; Methotrexate; Methoxsalen; Phenylbutazone; Photopheresis; Prednisone | 1994 |
New insights into the interactions between dendrimers and surfactants: 2. Design of new drug formulations based on dendrimer-surfactant aggregates.
Topics: Cell Survival; Chemistry, Pharmaceutical; Dendrimers; Drug Carriers; Drug Design; HeLa Cells; Humans; Methotrexate; Molecular Structure; Phenylbutazone; Solubility; Sulfamethoxazole; Surface-Active Agents | 2009 |
Host-guest chemistry of dendrimer-drug complexes. 3. Competitive binding of multiple drugs by a single dendrimer for combination therapy.
Topics: Binding, Competitive; Dendrimers; Drug Carriers; Drug Therapy, Combination; Magnetic Resonance Spectroscopy; Methotrexate; Mycophenolic Acid; Pharmaceutical Preparations; Phenylbutazone; Solubility | 2009 |