phenylbutazone and mercaptopurine

phenylbutazone has been researched along with mercaptopurine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199018 (78.26)18.7374
1990's0 (0.00)18.2507
2000's1 (4.35)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chang, YH2
Rovenský, J; Trnavský, K1
Begemann, H; Schick, P; Trepel, F1
Dlabac, A; Grimová, J; Hondlík, J; Likovský, Z; Smetana, K1
Andrews, TM; Chinn, S; Howell, A; Watts, RW1
Ginn, HE1
Jover, A; Levy, A; Migueres, J1
Fischer, J; Jahn, U; Wagner-Jauregg, T1
Arrigoni-Martelli, E; Schiatti, P; Selva, D1
Finkelstein, RA; Goth, A; Lexomboon, U1
Dietrich, FM; Komarek, A1
Dietrich, FM; Hess, R1
Kadokawa, T; Nakamura, H; Nakamura, K; Nakatsuji, K1
Chinea, G; Colombo, C; Graeme, ML; Piliero, SJ; Sigg, EB1
Nagra, CL; Rosenthale, ME1
Graeme, ML; John, M; Sigg, EB1

Reviews

1 review(s) available for phenylbutazone and mercaptopurine

ArticleYear
Late medical complications of renal transplantation.
    Archives of internal medicine, 1969, Volume: 123, Issue:5

    Topics: Adrenal Cortex Hormones; Adult; Allopurinol; Autoimmune Diseases; Azathioprine; Bone Diseases; Diabetes Mellitus; Drug Synergism; Duodenal Ulcer; Embolism, Fat; Glomerulonephritis; Histocompatibility; Humans; Hypertension, Renal; Immunosuppressive Agents; Infections; Kidney Glomerulus; Kidney Transplantation; Malabsorption Syndromes; Male; Mercaptopurine; Neoplasm Transplantation; Neoplasms; Obesity; Osteoporosis; Pancreatitis; Peptic Ulcer Hemorrhage; Phenylbutazone; Postoperative Complications; Proteinuria; Transplantation, Homologous

1969

Other Studies

22 other study(ies) available for phenylbutazone and mercaptopurine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mechanisms underlying the suppression of adjuvant-induced arthritis by 6-mercaptopurine.
    Arthritis and rheumatism, 1977, Volume: 20, Issue:5

    Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Carrageenan; Cell Line; Cyclophosphamide; Dose-Response Relationship, Drug; Edema; Immunity, Cellular; Mercaptopurine; Mice; Mice, Inbred Strains; Phenylbutazone; Rats; Time Factors

1977
Adjuvant polyarthritis. II. Suppression by tilorone.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:1

    Topics: Animals; Arthritis; Arthritis, Experimental; Cell Line; Fluorenes; Immunity; Immunity, Cellular; Inflammation; Male; Mercaptopurine; Neoplasms, Experimental; Phenylbutazone; Rats; Rats, Inbred Strains; Tilorone

1977
Influence of some antirheumatic drugs and cytostatics on urinary enzyme level.
    Pharmacology, 1976, Volume: 14, Issue:4

    Topics: Aminopeptidases; Animals; Cyclophosphamide; L-Lactate Dehydrogenase; Leucyl Aminopeptidase; Male; Mercaptopurine; Penicillamine; Phenylbutazone; Rats; Sodium Salicylate; Stimulation, Chemical

1976
[Morphological and functional alterations of the blood cell system of guinea pigs after treatment with cytostatic agents, prednisolone and phenylbutazone. I. Alterations of different leukocyte and lymphocyte subgroups in the blood].
    Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie, 1968, Volume: 148, Issue:4

    Topics: Animals; Antineoplastic Agents; Blood Cells; Cyclophosphamide; Dactinomycin; Guinea Pigs; Leukocytes; Leukopenia; Lymphocytes; Mercaptopurine; Phenylbutazone; Plants, Medicinal; Plants, Toxic; Podophyllum; Prednisolone; Triethylenemelamine; Vinblastine

1968
Morphological changes in nucleoli of lymphocytes and their influencing by trimethazone, phenylbutazone, indometacin, and 6-mercaptopurine in albino rats with adjuvant-induced disease.
    Naunyn-Schmiedeberg's archives of pharmacology, 1973, Volume: 276, Issue:2

    Topics: Adjuvants, Immunologic; Animals; Cell Nucleolus; Indomethacin; Joint Diseases; Ketones; Lymphocytes; Male; Mercaptopurine; Phenylbutazone; Pyrazoles; Rats; RNA

1973
Gout.
    British medical journal, 1974, Mar-09, Volume: 1, Issue:5905

    Topics: Allopurinol; Blood Cell Count; Cell Movement; Colchicine; Diet; Drug Synergism; Gastrointestinal Diseases; Gout; Hemorrhage; Humans; Indomethacin; Leukocytes; Mercaptopurine; Phenylbutazone; Probenecid; Purines; Uric Acid

1974
The effects of drugs that cause neutropenia upon colony formation by bone marrow cells in semi-solid agar.
    Clinical science and molecular medicine, 1974, Volume: 46, Issue:5

    Topics: Agar; Agranulocytosis; Animals; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Chloramphenicol; Clone Cells; Dose-Response Relationship, Drug; Gold; HeLa Cells; Humans; L Cells; Malates; Mercaptopurine; Methimazole; Mice; Neutrophils; Phenylbutazone; Sulfides; Thiouracil

1974
[3 years of polychemotherapy of pleuro-pulmonary cancer. Apropos of 95 cases].
    Le Poumon et le coeur, 1968, Volume: 24, Issue:1

    Topics: Androgens; Antibiotics, Antineoplastic; Antineoplastic Agents; Ascorbic Acid; Azirines; Bronchial Neoplasms; Carcinoma; Carcinoma, Squamous Cell; Cyclophosphamide; Drug Synergism; Fluorouracil; Glucocorticoids; Humans; Hydrazines; Injections, Intramuscular; Injections, Intravenous; Lectins; Lung Neoplasms; Mechlorethamine; Mercaptopurine; Mesothelioma; Methotrexate; Phenylbutazone; Pleural Neoplasms; Thiotepa; Vinblastine

1968
[Cytostatic antiphlogistics. II. Antimicrobial activity range and comparison in the Oedipus test].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antineoplastic Agents; Aspirin; Azaguanine; Azathioprine; Bacteria; Benzimidazoles; Depression, Chemical; Edema; Enterococcus faecalis; Flufenamic Acid; Fungi; Indomethacin; Lactobacillus; Mefenamic Acid; Mercaptopurine; Oxyphenbutazone; Phenylbutazone; Purines; Pyrimethamine; Rats; Riboflavin; Salicylates; Staphylococcus; Tetracycline; Thioguanine

1970
The influence of anti-inflammatory and immunosuppressant drugs on Nystatin induced oedema.
    Pharmacology, 1971, Volume: 5, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Arthritis; Aspirin; Azathioprine; Chloramphenicol; Cyclophosphamide; Dexamethasone; Drug Antagonism; Edema; Hydrocortisone; Immunosuppressive Agents; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Nystatin; Phenylacetates; Phenylbutazone; Prednisolone; Rats; Rifampin; Triamcinolone

1971
Applications of the mouse foot edema test in evaluation of anti-cholera drugs.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:2

    Topics: Animals; Anti-Infective Agents; Aspirin; Chloramphenicol; Cholera; Cycloheximide; Dactinomycin; Diuretics; Edema; Emetine; Enterotoxins; Ethacrynic Acid; Fasting; Furosemide; Indomethacin; Iproniazid; Mercaptopurine; Mice; Models, Biological; Phenylbutazone; Protein Biosynthesis; Puromycin; Time Factors; Triamcinolone

1971
Chemical prevention of experimental allergic encephalomyelitis in rats: a quantitative evaluation of steroids and various non-steroid drugs.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 193, Issue:2

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Bis-Trimethylammonium Compounds; Cortisone; Cyclophosphamide; Dexamethasone; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Female; Flumethasone; Freund's Adjuvant; Glucocorticoids; Guanethidine; Guinea Pigs; Hydrocortisone; Lethal Dose 50; Male; Mercaptopurine; Paramethasone; Phenylbutazone; Prednisolone; Prednisone; Rats; Sodium Salicylate; Spinal Cord

1971
Hypersensitivity in mice. I. Induction of contact sensitivity to oxazolone and inhibition by various chemical compounds.
    International archives of allergy and applied immunology, 1970, Volume: 38, Issue:3

    Topics: Animals; Antigens; Aspirin; Cortisone; Corynebacterium; Cyclophosphamide; Dermatitis, Contact; Dexamethasone; Drug Hypersensitivity; Ear; Flumethasone; Glucocorticoids; Immunosuppressive Agents; Mercaptopurine; Mice; Oxazoles; Paramethasone; Phenylbutazone; Prednisone; Skin Tests

1970
Pharmacological studies of a new anti-inflammatory drug, 1-phenylsulfonyl-5,5-diphenylhydantoin (PC-796) in experimental animals. I. Anti-inflammatory, analgesic and anti-pyretic activity.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Analgesics; Anaphylaxis; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Capillary Permeability; Carrageenan; Croton Oil; Depression, Chemical; Edema; Exudates and Transudates; Female; Guinea Pigs; Indomethacin; Inflammation; Male; Mefenamic Acid; Mercaptopurine; Mice; Phenylbutazone; Phenytoin; Pregnanes; Protein Denaturation; Rabbits; Radiation-Protective Agents; Rats; Sulfones; Yeast, Dried

1970
Action of anti-inflammatory agents upon blood and histopathologic changes induced by periarthritis in rats.
    Life sciences, 1966, Volume: 5, Issue:12

    Topics: Adrenal Glands; Animals; Blood Cell Count; Blood Protein Electrophoresis; Blood Sedimentation; Chlorpromazine; Fibrinogen; Indomethacin; Male; Mercaptopurine; Methotrexate; Organ Size; Oxyphenbutazone; Paramethasone; Phenylbutazone; Rats; Spleen; Streptomycin; Thymus Gland

1966
Comparative effects of some immunosuppressive and anti-inflammotory drugs on allergic encephalomyelitis and adjuvant arthritis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1967, Volume: 125, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Blood Cell Count; Body Weight; Cortisone; Encephalomyelitis, Autoimmune, Experimental; Immunosuppressive Agents; Male; Mercaptopurine; Organ Size; Phenylbutazone; Rats

1967
Induction of periarthritis by oral administration of 6-sulfanilamidoindazole and its treatment in rats.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 157, Issue:1

    Topics: Animals; Aspirin; Chloroquine; Cloxacillin; Hydralazine; Hydrocortisone; Indomethacin; Male; Mercaptopurine; Methotrexate; Morphine; ortho-Aminobenzoates; Oxyphenbutazone; Paramethasone; Periarthritis; Phenylbutazone; Rats; Sulfinpyrazone; Sulfonamides

1967