phenylbutazone and hexobarbital

phenylbutazone has been researched along with hexobarbital in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199019 (86.36)18.7374
1990's1 (4.55)18.2507
2000's1 (4.55)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asai, H; Izumi, K; Kato, K; Kitamikado, T; Ohno, S; Ohtani, O; Sugiura, S1
Topliss, JG; Yoshida, F1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ford, JH; Gopinath, C1
Conney, AH; Kuntzman, R; Welch, R1
Friemel, G; Kurz, H1
Kurz, H; Mohr, E1
Greengard, P; Quinn, GP; Reid, MB1
Martelli, EA1
Banci, F; Tubaro, E1
Fujimura, H; Go, K; Hayashi, M; Nakano, K; Tsurumi, K1
Azarnoff, DL; Mustala, OO1
Ankermann, H; Elger, J; Franke, H; Klinger, W; Reinicke, C; Traeger, A; Volkmann, H; Wahrenberg, I1
Grosman, IuS; Zaks, AS; Zilbermints, LG1
Adrian, RW; Jahn, U1
Catanese, B; Del Basso, P; Silvestrini, B1
Erba, G; Marazzi-Uberti, E; Turba, C1
Lake, BG; Lewis, DF1
MANNERING, GJ; RUBIN, A; TEPHLY, TR1
KLEMPAU, I; KORANSKY, W; PORTIG, J; VOHLAND, HW1
BURNS, JJ1
CONNEY, AH; JACOBSON, M; KUNTZMAN, R; SCHNEIDMAN, K1

Reviews

2 review(s) available for phenylbutazone and hexobarbital

ArticleYear
Factors influencing steroid hydroxylases in liver microsomes.
    Advances in enzyme regulation, 1966, Volume: 4

    Topics: Age Factors; Animals; Carbon Isotopes; Chlordan; DDT; Dogs; Estradiol; Guinea Pigs; Hexobarbital; In Vitro Techniques; Insecticides; Liver; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen Consumption; Phenobarbital; Phenylbutazone; Phosphates; Polycyclic Compounds; Proadifen; Progesterone; Rabbits; Rats; Sex Factors; Steroids; Testosterone

1966
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY.
    The American journal of medicine, 1964, Volume: 37

    Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine

1964

Other Studies

20 other study(ies) available for phenylbutazone and hexobarbital

ArticleYear
Synthesis and antiinflammatory and hypnotic activity of 5-alkoxy-3-(N-substituted carbamoyl)-1-phenylpyrazoles.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Carbamates; Hypnotics and Sedatives; Lethal Dose 50; Mice; Pyrazoles

1977
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
The role of microsomal hydroxylases in the modification of chloroform hepatotoxicity in rats.
    British journal of experimental pathology, 1975, Volume: 56, Issue:5

    Topics: Animals; Carbon Disulfide; Chemical and Drug Induced Liver Injury; Chloroform; Chlorpromazine; DDT; Ditiocarb; Drug Interactions; Enzyme Induction; Female; Hexobarbital; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Phenylbutazone; Proadifen; Rats; Sleep

1975
[Species specific difference in binding to plasma proteins].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:1

    Topics: Aminobenzoates; Aniline Compounds; Animals; Barbiturates; Blood Proteins; Cattle; Chlorpromazine; Dipyridamole; Dogs; Guanidines; Guinea Pigs; Hexobarbital; Methohexital; Mice; Nitrofurantoin; Pentobarbital; Phenylbutazone; Protein Binding; Rabbits; Rats; Salicylamides; Salicylates; Species Specificity; Sulfadimethoxine; Sulfaguanidine; Sulfinpyrazone; Sulfonamides; Swine; Thiopental

1967
[Influence of acidosis and alkalosis on the binding of drugs to plasma proteins].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Acidosis; Alkalosis; Aniline Compounds; Animals; Blood Proteins; Cattle; Chemical Phenomena; Chemistry; Chlorpromazine; Hexobarbital; Hydrogen-Ion Concentration; Methohexital; Nitrofurantoin; Pentobarbital; Phenylbutazone; Protein Binding; Quinine; Salicylamides; Salicylates; Thiopental

1968
Prevention by antidepressant drugs of reserpine effect on pyridine nucleotide metabolism.
    Molecular pharmacology, 1966, Volume: 2, Issue:4

    Topics: Aminopyrine; Amitriptyline; Amphetamine; Animals; Antidepressive Agents; Atropine; Benactyzine; Caffeine; Chlorpheniramine; Chlorpromazine; Female; Hexobarbital; Hydralazine; Hypothalamus; Imipramine; Iproniazid; Isoniazid; Liver; Meprobamate; Methacholine Compounds; Morphine; NAD; Niacinamide; Pargyline; Pentobarbital; Phenylbutazone; Phenytoin; Quinacrine; Rats; Reserpine; Tranylcypromine; Tripelennamine; Zoxazolamine

1966
Antagonism of anti-inflammatory drugs on bradykinin-induced increase of capillary permeability.
    The Journal of pharmacy and pharmacology, 1967, Volume: 19, Issue:9

    Topics: Acetates; Animals; Anti-Inflammatory Agents; Aspirin; Bradykinin; Bretylium Compounds; Capillary Permeability; Chlorothiazide; Female; Hexobarbital; Mecamylamine; Mefenamic Acid; ortho-Aminobenzoates; Papaverine; Phenylbutazone; Rats; Reserpine; Sodium Salicylate; Urethane

1967
Pharmacology of a nicotinamido-methylaminopyrazolone (Ra 101).
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Aminopyrine; Amphetamine; Analgesics; Animals; Anti-Inflammatory Agents; Anticonvulsants; Carrageenan; Croton Oil; Depression, Chemical; Dextrans; Drug Synergism; Edema; Female; Fever; Glutethimide; Granuloma; Hexobarbital; Histamine H1 Antagonists; Hypnotics and Sedatives; Male; Mice; Motor Activity; Pentylenetetrazole; Phenylbutazone; Polysaccharides, Bacterial; Pyrazoles; Rabbits; Rats; Seizures

1970
[Pharmacological studies of niflumic acid, with special reference to the comparison with fenamates. 2. General pharmacological effects].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:6

    Topics: Aniline Compounds; Animals; Body Temperature; Digestive System; Electric Stimulation; Electrocardiography; Electrolytes; Female; Flufenamic Acid; Fluorine; Guinea Pigs; Hemodynamics; Hexobarbital; In Vitro Techniques; Indomethacin; Kidney; Locomotion; Male; Mefenamic Acid; Mice; Muscle Contraction; Nicotinic Acids; Phenylbutazone; Rabbits; Rats; Respiration; Sleep; Thymus Gland; Uterus

1972
Effect of oxygen tension on drug levels and pharmacological action in the intact animal.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 132, Issue:1

    Topics: Animals; Barbiturates; Brain Chemistry; Hexobarbital; Hyperbaric Oxygenation; Hypoxia; Isoniazid; Male; Phenylbutazone; Propiophenones; Rats; Sulfadiazine; Warfarin; Zoxazolamine

1969
[Studies on the mechanism of enzyme induction. XV. Induction pattern and submicroscopic changes in the liver following application of phenylbutazone in rats of different ages].
    Acta biologica et medica Germanica, 1970, Volume: 24, Issue:4

    Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Ascorbic Acid; Cholestasis; Endoplasmic Reticulum; Enzyme Induction; Female; Fetus; Hexobarbital; Liver; Lysosomes; Male; Methylcholanthrene; Microscopy, Electron; Mitochondria, Liver; Phenylbutazone; Pregnancy; Rats

1970
[The influence of anti-inflammatory agents on the central effects of barbiturates].
    Biulleten' eksperimental'noi biologii i meditsiny, 1968, Volume: 66, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Barbiturates; Brain; Drug Synergism; Female; Hexobarbital; Male; Mice; Muscle Relaxants, Central; Phenobarbital; Phenylbutazone; Sodium Salicylate

1968
[Pharmacological and toxicological testing of new anti-inflammatory agent azapropazon=3-dimethylamine-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:1

    Topics: Abnormalities, Drug-Induced; Analgesics; Anesthetics, Local; Animals; Anti-Inflammatory Agents; Blood Glucose; Blood Pressure; Bradykinin; Cats; Cholesterol; Diuresis; Dogs; Drug Synergism; Edema; Erythema; Female; Flufenamic Acid; Granuloma; Guinea Pigs; Heart Rate; Hexobarbital; In Vitro Techniques; Indomethacin; Inflammation; Irritants; Male; Mefenamic Acid; Mice; Muscles; Orientation; Phenylbutazone; Rabbits; Radiation-Protective Agents; Rats; Respiration; Stomach Ulcer; Triazines

1969
Researches on the increase of liver weight produced by some drugs.
    Biochemical pharmacology, 1966, Volume: 15, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Chlorpromazine; Hexobarbital; Liver; Mice; Organ Size; Phenylbutazone; Proadifen; Sulfobromophthalein

1966
Alpha-Isopropyl-alpha-(2-dimethylaminoethyl)-1-naphthylacetamide (naphthypramide, DA 992): a new anti-inflammatory agent. II. Antipyretic, analgesic and C.N.S. depressant activity.
    Archives internationales de pharmacodynamie et de therapie, 1966, Volume: 162, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Body Temperature; Central Nervous System; Cornea; Drug Synergism; Ear, External; Hexobarbital; Mephenesin; Movement; Phenylbutazone; Rats; Reflex

1966
Molecular modelling of mammalian CYP2B isoforms and their interaction with substrates, inhibitors and redox partners.
    Xenobiotica; the fate of foreign compounds in biological systems, 1997, Volume: 27, Issue:5

    Topics: Amino Acid Sequence; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Feprazone; Hexobarbital; Humans; Isoenzymes; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Phenobarbital; Phenylbutazone; Rabbits; Rats; Sequence Homology, Amino Acid; Structure-Activity Relationship; Substrate Specificity; Templates, Genetic

1997
KINETICS OF DRUG METABOLISM BY HEPATIC MICROSOMES.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Acetanilides; Chlorpromazine; Hexobarbital; Kinetics; Liver; Metabolism; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Morphine; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylbutazone; Rats; Research; Zoxazolamine

1964
[ACTIVATION OF MICROSOME ENZYMES BY HEXACHLOROCYCLOHEXANE ISOMERS. ITS EFFECT ON SCILLIROSIDE POISONING IN RATS].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, Apr-09, Volume: 247

    Topics: Bufanolides; Drug Tolerance; Ethionine; Hexachlorocyclohexane; Hexobarbital; Liver; Microsomes; Nikethamide; Pharmacology; Phenylbutazone; Plants, Medicinal; Rats; Research; Rodenticides; Toxicology; Transferases

1964
DRUG-INDUCED CHANGES IN STEROID METABOLISM.
    Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123

    Topics: Androsterone; Chromatography; Corticosterone; Cortisone; Dogs; Estradiol; Hexobarbital; Histamine H1 Antagonists; Hydrocortisone; Liver; Methylcholanthrene; Mice; Microsomes; Phenobarbital; Phenylbutazone; Piperazines; Rats; Research; Steroids; Testosterone; Toxicology

1965