phenylbutazone and flurbiprofen

phenylbutazone has been researched along with flurbiprofen in 28 studies

Research

Studies (28)

Timeframe	Studies, this research(%)	All Research%
pre-1990	14 (50.00)	18.7374
1990's	2 (7.14)	18.2507
2000's	3 (10.71)	29.6817
2010's	7 (25.00)	24.3611
2020's	2 (7.14)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Apiwattanakul, N; Chairoungdua, A; Endou, H; Kanai, Y; Nakajima, N; Sekine, T; Sophasan, S	1
Topliss, JG; Yoshida, F	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Chang, TK; Ensom, MH; Kiang, TK	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Gozalbes, R; Pineda-Lucena, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Kumar, M; Sinha, VR; Thareja, S	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Nozu, K	1
van der Wal-Komproe, LE; van Duin, CT; van Miert, AS	1
Mena, HR; Willkens, RF	1
Gharpure, MB; Kulkarni, RD; Kulkarni, VN; Mehta, DJ; Pispati, PK; Vakil, BJ	1
Dalal, NJ; Pispati, PK; Shah, PN; Vakil, BJ; Wagholikar, UN	1
Di Mummo, O; Ferri, S; Franco, PA	1
Bhasin, RC; Bhuttani, P; Krishnan, CV; Sachdev, S	1
Kudo, M; Ofuji, T; Okumura, M	1
Adams, SS; McCullough, KF; Nicholson, JS	1
Crittenden, N; Fitzpatrick, F; McGee, J; McGuire, J	1
Butler, RC; Goddard, DH; Higgens, CS; Hollingworth, P; Pease, CT; Scott, JT; Stodell, MA	1
Brinn, EL; Lamborn, KR; Lomen, PL; Sattler, LP; Turner, LF	1
Baumüller, A; Esders, K	1
Feron, VJ; Groene, EM; Horbach, GJ; Kappers, WA; Kleij, LA; Witkamp, RF; Zweers-Zeilmaker, WM	1
Glatz, Z; Michalcová, L; Nevídalová, H	1
Du, G; Fang, Z; Gong, N; Lu, Y; Xing, C; Xing, W; Yu, H; Zhang, B	1

Reviews

2 review(s) available for phenylbutazone and flurbiprofen

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
[Adjuvant therapy with nonsteroidal antiphlogistics in disease of the urogenital tract]. Fortschritte der Medizin, 1984, Dec-06, Volume: 102, Issue:45 Topics: Anti-Inflammatory Agents; Aspirin; Diclofenac; Diflunisal; Escin; Flurbiprofen; Humans; Indomethacin; Oxyphenbutazone; Phenylbutazone; Piroxicam; Thiazines; Urologic Diseases	1984

Trials

7 trial(s) available for phenylbutazone and flurbiprofen

Article	Year
Treatment of ankylosing spondylitis with flurbiprofen or phenylbutazone. European journal of clinical pharmacology, 1977, Apr-20, Volume: 11, Issue:4 Topics: Clinical Trials as Topic; Drug Evaluation; Female; Flurbiprofen; Humans; Male; Phenylbutazone; Propionates; Spondylitis, Ankylosing; Time Factors	1977
Estimation of gastro-intestinal blood loss in volunteers treated with non-steroidal anti-inflammatory agents. Current medical research and opinion, 1977, Volume: 5, Issue:1 Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Feces; Flurbiprofen; Gastrointestinal Hemorrhage; Humans; Male; Phenylbutazone; Propionates	1977
Endoscopic study of gastro-intestinal injury with non-steroidal anti-inflammatory drugs. Current medical research and opinion, 1977, Volume: 5, Issue:1 Topics: Adult; Aspirin; Clinical Trials as Topic; Double-Blind Method; Flurbiprofen; Gastrointestinal Diseases; Gastroscopy; Humans; Male; Phenylbutazone; Placebos; Propionates	1977
Controlled clinical trial comparing flurbiprofen and phenylbutazone in patients with rheumatoid arthritis. Current medical research and opinion, 1977, Volume: 5, Issue:1 Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Flurbiprofen; Humans; Phenylbutazone; Propionates	1977
Flurbiprofen and phenylbutazone in rheumatoid arthritis and osteoarthrosis: a double-blind study. The Journal of the Association of Physicians of India, 1979, Volume: 27, Issue:5 Topics: Adult; Arthritis, Rheumatoid; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Osteoarthritis; Phenylbutazone; Propionates	1979
Double-blind trial of flurbiprofen and phenylbutazone in acute gouty arthritis. British journal of clinical pharmacology, 1985, Volume: 20, Issue:5 Topics: Adult; Aged; Arthritis; Clinical Trials as Topic; Double-Blind Method; Flurbiprofen; Gout; Humans; Middle Aged; Phenylbutazone; Propionates; Random Allocation	1985
Flurbiprofen in the treatment of ankylosing spondylitis. A comparison with phenylbutazone. The American journal of medicine, 1986, Mar-24, Volume: 80, Issue:3A Topics: Adolescent; Adult; Drug Evaluation; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain; Phenylbutazone; Propionates; Spondylitis, Ankylosing	1986

Other Studies

19 other study(ies) available for phenylbutazone and flurbiprofen

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Transport properties of nonsteroidal anti-inflammatory drugs by organic anion transporter 1 expressed in Xenopus laevis oocytes. Molecular pharmacology, 1999, Volume: 55, Issue:5 Topics: Animals; Anion Transport Proteins; Anti-Inflammatory Agents, Non-Steroidal; Biological Transport; Carrier Proteins; Oocytes; Xenopus laevis	1999
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
QSAR-based solubility model for drug-like compounds. Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19 Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. European journal of medicinal chemistry, 2012, Volume: 53 Topics: Anti-Inflammatory Agents, Non-Steroidal; Chemical Phenomena; Computational Biology; Least-Squares Analysis; Models, Molecular; Molecular Conformation; Quantitative Structure-Activity Relationship	2012
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Flurbiprofen: highly potent inhibitor of prostaglandin synthesis. Biochimica et biophysica acta, 1978, Jun-23, Volume: 529, Issue:3 Topics: Animals; Arachidonic Acids; Aspirin; Cattle; Cyclooxygenase Inhibitors; Flurbiprofen; Ibuprofen; Indomethacin; Male; Microsomes; Oxygen Consumption; Phenylbutazone; Propionates; Prostaglandins E; Seminal Vesicles	1978
Effects of antipyretic agents on fever and ruminal stasis induced by endotoxins in conscious goats. Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 225, Issue:1 Topics: Acetaminophen; Analgesics; Animals; Body Temperature; Dipyrone; Drug Interactions; Endotoxins; Escherichia coli; Female; Flurbiprofen; Gastrointestinal Motility; Goats; Heart Rate; Male; Meclofenamic Acid; Phenylbutazone; Pressure; Rumen; Salmonella typhimurium; Time Factors	1977
[Comparative studies on gastrointestinal damage induced by non-steroidal anti-inflammatory drugs in rats (author's transl)]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1978, Volume: 98, Issue:8 Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Male; Phenylbutazone; Rats; Stomach Ulcer	1978
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. Arzneimittel-Forschung, 1975, Volume: 25, Issue:11 Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Capillary Permeability; Codeine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Edema; Erythema; Female; Fever; Flurbiprofen; Guinea Pigs; Indomethacin; Inflammation; Liver Glycogen; Male; Mice; Phenylbutazone; Propionates; Rats; Spasm	1975
Cell damage unmasks 15-lipoxygenase activity in human neutrophils. The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14 Topics: Acetates; Arachidonate Lipoxygenases; Aspirin; Dose-Response Relationship, Drug; Etodolac; Fluorometry; Flurbiprofen; Humans; Hydroxyeicosatetraenoic Acids; Ibuprofen; L-Lactate Dehydrogenase; Lipoxygenase; Naproxen; Neutrophils; Phenylbutazone	1985
Inhibition of tolbutamide 4-methylhydroxylation by a series of non-steroidal anti-inflammatory drugs in V79-NH cells expressing human cytochrome P4502C10. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:12 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Cell Line; Cricetinae; Cricetulus; Cytochrome P-450 CYP2C9; Cytochrome P-450 Enzyme System; Diclofenac; Drug Interactions; Enzyme Inhibitors; Flurbiprofen; Gene Expression; Humans; Hydroxylation; Ketoprofen; Lung; Methylation; Mixed Function Oxygenases; Phenylbutazone; Sulfaphenazole; Tolbutamide; Transfection	1996
Applicability of capillary electrophoresis-frontal analysis for displacement studies: Effect of several drugs on l-tryptophan and lidocaine binding to human serum albumin. Journal of separation science, 2020, Volume: 43, Issue:22 Topics: Binding Sites; Chlorpropamide; Diclofenac; Electrophoresis, Capillary; Flurbiprofen; Humans; Ibuprofen; Lidocaine; Phenylbutazone; Serum Albumin, Human; Tolbutamide; Tryptophan	2020
An Evolving Role of Aqueous Piperazine to Improve the Solubility of Non-Steroidal Anti-Inflammatory Drugs. Journal of pharmaceutical sciences, 2022, Volume: 111, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Flurbiprofen; Ibuprofen; Indomethacin; Ketoprofen; Phenylbutazone; Piperazine; Powders; Salts; Solubility; Spectroscopy, Fourier Transform Infrared; Sulindac; Water; X-Ray Diffraction	2022