Compounds > phenylbutazone

phenylbutazone and desipramine

phenylbutazone has been researched along with desipramine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's0 (0.00)18.2507
2000's4 (22.22)29.6817
2010's5 (27.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Gozalbes, R; Pineda-Lucena, A1
Ekins, S; Williams, AJ; Xu, JJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Hurwic, MJ; Kanzler, MB; Perel, JM1
Passananti, GT; Vessell, ES1
Bhargava, KP; Saxena, PR; Seth, PK; Tangri, KK1
Consolo, S1
Rowland, M1
Alexanderson, B; Azarnoff, DL; Orrenius, S; Sjoqvist, F; von Bahr, C1
Consolo, S; Garattini, S; Morselli, PL; Zaccala, M1
Consolo, S; Garattini, S1

Reviews

2 review(s) available for phenylbutazone and desipramine

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
Utility of clinical chemical determinations of drug concentrations in biological fluids.
    Clinical chemistry, 1971, Volume: 17, Issue:9

    Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays

1971

Trials

1 trial(s) available for phenylbutazone and desipramine

ArticleYear
Pharmacodynamics of imipramine in depressed patients.
    Psychopharmacology bulletin, 1975, Volume: 11, Issue:4

    Topics: Clinical Trials as Topic; Depression; Desipramine; Half-Life; Humans; Imipramine; Phenylbutazone

1975

Other Studies

15 other study(ies) available for phenylbutazone and desipramine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
QSAR-based solubility model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2010, Oct-01, Volume: 18, Issue:19

    Topics: Databases, Factual; Models, Molecular; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Solubility; Water

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Anti-inflammatory activity of imipramine and congeners.
    Biochemical pharmacology, 1966, Volume: 15, Issue:7

    Topics: Adenosine Triphosphatases; Alanine Transaminase; Amitriptyline; Animals; Arthritis; Aspartate Aminotransferases; Brain; Bronchial Spasm; Desipramine; Formaldehyde; Histamine; Hydrocortisone; Imipramine; Liver; Lysergic Acid Diethylamide; Phenylbutazone; Rats; Serotonin

1966
An interaction between desipramine and phenylbutazone.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20, Issue:7

    Topics: Animals; Desipramine; Drug Antagonism; Female; Phenylbutazone; Rats

1968
Application of clearance concepts to some literature data on drug metabolism in the isolated perfused liver preparation and in vivo.
    European journal of pharmacology, 1972, Volume: 17, Issue:3

    Topics: Analgesics; Animals; Antidepressive Agents; Antipyrine; Desipramine; Half-Life; In Vitro Techniques; Ketones; Kinetics; Liver; Models, Biological; Nortriptyline; Perfusion; Phenylbutazone; Rats; Tremorine

1972
A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats.
    European journal of pharmacology, 1970, Volume: 9, Issue:1

    Topics: Animals; Antipyrine; Desipramine; Enzyme Induction; In Vitro Techniques; Liver; Male; Nortriptyline; Perfusion; Phenobarbital; Phenylbutazone; Rats; Tremorine

1970
Delayed absorption of phenylbutazone caused by desmethylimipramine in humans.
    European journal of pharmacology, 1970, Volume: 10, Issue:2

    Topics: Depression; Desipramine; Female; Humans; Male; Phenylbutazone; Time Factors

1970
Effect of desipramine on intestinal absorption of phenylbutazone and other drugs.
    European journal of pharmacology, 1969, Volume: 6, Issue:3

    Topics: Amphetamine; Animals; Desipramine; Female; Hydrocortisone; Intestinal Absorption; Intestine, Small; Muscle, Smooth; Oxyphenbutazone; Pentobarbital; Phenylbutazone; Rats; Salicylates; Stomach

1969