phenylbutazone and clofibrate

phenylbutazone has been researched along with clofibrate in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199014 (60.87)18.7374
1990's1 (4.35)18.2507
2000's3 (13.04)29.6817
2010's5 (21.74)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Kapoor, A; Veronich, K; White, G1
Calvo, R; Carlos, R; Erill, S1
Hucker, HB; Stauffer, SC; White, SE1
O'Reilly, RA3
McQueen, EG1
Sellers, E; Weser, JK1
Flower, R; Gryglewski, R; Herbaczyńska-Cedro, K; Vane, JR1
Vargaftig, BB; Zirinis, P1
Eipe, J1
Nies, AS1
Aggeler, PM; O'Reilly, RA1
Abrams, WB; Reich, S; Solomon, HM; Spirt, N1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM1

Reviews

8 review(s) available for phenylbutazone and clofibrate

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
The pharmacodynamics of the oral anticoagulant drugs.
    Progress in hemostasis and thrombosis, 1974, Volume: 2, Issue:0

    Topics: Administration, Oral; Animals; Anticoagulants; Blood Coagulation; Blood Coagulation Factors; Blood Proteins; Clofibrate; Coumarins; Dicumarol; Disulfiram; Ethyl Biscoumacetate; Female; Heparin; Intestinal Absorption; Liver; Phenylbutazone; Protein Binding; Prothrombin; Prothrombin Time; Rabbits; Rats; Salicylates; Sulfonamides; Vitamin K; Vitamin K Deficiency; Warfarin

1974
Hazards of anticoagulant treatment: other drugs, other diseases.
    Thrombosis et diathesis haemorrhagica. Supplementum, 1973, Volume: 56

    Topics: Administration, Oral; Animals; Anticoagulants; Barbiturates; Biological Transport; Blood Coagulation Factors; Clofibrate; Cycloheptanes; Depression, Chemical; Dicumarol; Disulfiram; Drug Interactions; Drug Synergism; Feces; Female; Half-Life; Humans; Hypoprothrombinemias; Infant, Newborn; Phenylbutazone; Pregnancy; Prothrombin Time; Rats; Receptors, Drug; Serum Albumin; Vitamin K Deficiency; Warfarin

1973
Drug interactions with coumarin anticoagulants. 2.
    The New England journal of medicine, 1971, Sep-02, Volume: 285, Issue:10

    Topics: Allopurinol; Anabolic Agents; Animals; Anti-Bacterial Agents; Anticoagulants; Barbiturates; Chloral Hydrate; Chloramphenicol; Cholestyramine Resin; Clofibrate; Contraceptives, Oral; Coumarins; Dextrothyroxine; Diuretics; Drug Antagonism; Drug Synergism; Ethacrynic Acid; Ethanol; Glucagon; Glucocorticoids; Glutethimide; Humans; Oxyphenbutazone; Phenylbutazone; Quinidine; Quinine; Quinolines; Salicylates; Sulfinpyrazone; Sulfonamides; Thyroid Hormones; Tolbutamide

1971
Drugs affecting therapy with anticoagulants.
    The Medical clinics of North America, 1972, Volume: 56, Issue:1

    Topics: Anticoagulants; Chloramphenicol; Clofibrate; Contraceptives, Oral; Coumarins; Diuretics; Drug Interactions; Drug Synergism; Drug-Related Side Effects and Adverse Reactions; Estrogens; Ethanol; Heparin; Humans; Hypnotics and Sedatives; Phenylbutazone; Phenytoin; Salicylates; Thyroxine; Tolbutamide; Vitamin K

1972
Drug interactions.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Anabolic Agents; Antidepressive Agents; Biological Transport, Active; Cholestyramine Resin; Clofibrate; Drug Interactions; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kaolin; Kidney; Pharmaceutical Preparations; Phenylbutazone; Probenecid; Protein Binding; Thyroxine; Warfarin

1974
Drug interactions involving oral anticoagulants.
    Cardiovascular clinics, 1974, Volume: 6, Issue:2

    Topics: Animals; Anticoagulants; Barbiturates; Blood Coagulation; Blood Coagulation Factors; Cholestyramine Resin; Clofibrate; Disulfiram; Diuretics; Dogs; Drug Interactions; Heparin; Humans; In Vitro Techniques; Intestinal Absorption; Kinetics; Liver Diseases; Phenylbutazone; Protein Binding; Prothrombin Time; Rats; Receptors, Drug; Salicylates; Serum Albumin; Time Factors; Vitamin K; Vitamin K Deficiency

1974
Determinants of the response to oral anticoagulant drugs in man.
    Pharmacological reviews, 1970, Volume: 22, Issue:1

    Topics: Administration, Oral; Adrenal Cortex Hormones; Animals; Anti-Bacterial Agents; Anticoagulants; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Factors; Clofibrate; Coumarins; Diuresis; Dogs; Heparin; Humans; Hypnotics and Sedatives; Liver Diseases; Metabolic Diseases; Phenylbutazone; Rats; Salicylates; Sulfonamides; Thrombosis; Uremia; Vitamin K

1970

Other Studies

15 other study(ies) available for phenylbutazone and clofibrate

ArticleYear
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Effects of phenylbutazone, tolbutamide, and clofibric acid on binding of racemic warfarin and its enantiomers to human serum albumin.
    Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:12

    Topics: Binding, Competitive; Clofibrate; Clofibric Acid; Humans; Kinetics; Phenylbutazone; Protein Binding; Serum Albumin; Stereoisomerism; Tolbutamide; Warfarin

1979
Underestimation of albumin content by bromocresol green, induced by drug displacers and uremia.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:2

    Topics: Adult; Bromcresol Green; Clofibrate; Clofibric Acid; Cresols; Electrophoresis, Cellulose Acetate; Humans; Phenylbutazone; Protein Binding; Serum Albumin; Uremia

1985
Effect of halofenate on binding of various drugs to human plasma proteins and on the plasma half-life of antipyrine in monkeys.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:9

    Topics: Acetamides; Animals; Anticholesteremic Agents; Antipyrine; Aspirin; Blood Proteins; Carbon Isotopes; Chlorothiazide; Clofibrate; Dicumarol; Digitoxin; Drug Interactions; Fluorine; Glycolates; Half-Life; Haplorhini; Humans; Hypolipidemic Agents; Indomethacin; Macaca; Phenothiazines; Phenylbutazone; Salicylates; Warfarin

1972
Drug displacement from protein-binding and redistributional interactions.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Animals; Blood Proteins; Carboxylic Acids; Clofibrate; DDT; Dieldrin; Guanidines; Hexachlorocyclohexane; Humans; Kinetics; Oxyphenbutazone; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Protein Binding; Rats; Sheep; Ultrafiltration; Warfarin

1974
Effects of anti-inflammatory drugs on prostaglandin biosynthesis.
    Nature: New biology, 1972, Jul-26, Volume: 238, Issue:82

    Topics: Acetaminophen; Aldosterone; Animals; Anti-Inflammatory Agents; Aspirin; Azathioprine; Benzoates; Biological Assay; Clofibrate; Dexamethasone; Dogs; Edema; Fludrocortisone; Hydrocortisone; In Vitro Techniques; Indomethacin; Mefenamic Acid; Oxygenases; Phenylbutazone; Prostaglandins; Rats; Spleen; Triamcinolone Acetonide

1972
Platelet aggregation induced by arachidonic acid is accompanied by release of potential inflammatory mediators distinct from PGE2 and PGF2.
    Nature: New biology, 1973, Jul-25, Volume: 244, Issue:134

    Topics: Acetaminophen; Anti-Inflammatory Agents; Aorta; Arachidonic Acids; Aspirin; Biological Assay; Blood Platelets; Clofibrate; Glycerol; Indomethacin; Inflammation; Phenylbutazone; Platelet Adhesiveness; Prostaglandins; Tissue Extracts; Vasoconstrictor Agents

1973
Interactions between digitoxin and other drugs in vitro and in vivo.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Binding Sites; Cell Membrane Permeability; Chemical Phenomena; Chemistry; Clofibrate; Digitoxin; Digoxin; Drug Antagonism; Enzyme Induction; Erythrocytes; Humans; Microsomes, Liver; Phenobarbital; Phenylbutazone; Phenytoin; Protein Binding; Radioisotopes; Rubidium; Serum Albumin; Sulfadimethoxine; Tolbutamide; Tritium; Warfarin

1971
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3

    Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics

1999