phenylalanylglycine and glycylproline

phenylalanylglycine has been researched along with glycylproline* in 2 studies

Other Studies

2 other study(ies) available for phenylalanylglycine and glycylproline

ArticleYear
[Chemical Constituents of n-Butanol Extract of Myrothecium verrucaria].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2016, Volume: 39, Issue:3

    To study the chemical constituents of n-butanol extract in the broth of Myrothecium verrucaria.. The chemical constituents were isolated,purified and identified by various chromatographic and spectral techniques.. 14 compounds were isolated and identified from n-butanol extracts of Myrothecium verrucaria broth. They were identified as cyclo-( Pro-Phe)( 1),cyclo-( 4-OH-Pro-Phe)( 2),cyclo-( 4-OH-Pro-Leu)( 3),cyclo-( Ala-Pro)( 4),cyclo-( 4-methyl-Pro-9-propyl-Gly)( 5),cyclo-( Pro-Gly)( 6),cyclo-( Phe-Gly)( 7),cyclo-( Leu-Leu)( 8),N-acetyl tryptamine( 9),N-( 2-phenylethyl) acetamide( 10),N-( 2-hydroxyphenethyl) acetamide( 11),N-( 4-hydroxyphenethyl) acetamide( 12),uracil( 13) and thymine( 14).. Compounds 1 ~ 14 are obtained from the strain Myrothecium verrucaria for the first time.

    Topics: 1-Butanol; Dipeptides

2016
Carrier-mediated uptake of cephalexin in human intestinal cells.
    Biochemical and biophysical research communications, 1988, Sep-15, Volume: 155, Issue:2

    A transport carrier for cephalexin, a cephalosporin antibiotic, was identified in a human intestinal cell line, HT-29. Uptake via the carrier was inhibited by dipeptides, phe-gly, gly-pro, carnosine, and cefaclor, a close drug analog. Uptake was unaffected by the presence of amino acids. The pH optimum for uptake was 6.2. Drug uptake was not dependent on the presence of sodium and was insensitive to metabolic inhibitors. The efflux of cephalexin was stimulated by extracellular carnosine, indicating counter-transport. Taken together, drug uptake is mediated by a dipeptide transport carrier and not by an amino acid transport carrier. This is the first demonstration of the carrier in an established cell line.

    Topics: Carnosine; Carrier Proteins; Cefaclor; Cell Line; Cephalexin; Dipeptides; Humans; Hydrogen-Ion Concentration; Intestinal Mucosa; Intestines

1988