phenylalanyl-prolyl-arginine-chloromethyl ketone and tirofiban

phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with tirofiban in 5 studies

Compound Research Comparison

Studies (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Trials (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Recent Studies (post-2010) (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Studies (tirofiban)	Trials (tirofiban)	Recent Studies (post-2010) (tirofiban)
191	4	23	1,210	309	427

Protein Interaction Comparison

Protein	Taxonomy	tirofiban (IC50)
Integrin subunit alpha 2b	Rattus norvegicus (Norway rat)	0.13
Integrin beta-3	Homo sapiens (human)	0.1184
Integrin alpha-V	Homo sapiens (human)	0.011
Integrin alpha-IIb	Homo sapiens (human)	0.1225
Integrin beta-3	Rattus norvegicus (Norway rat)	0.13

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Proimos, G	1
Ito, H; Kimura, Y; Ozeki, Y; Sudo, T	1
Kereiakes, DJ; Kukielka, G; Lorenz, T; Mueller, MN; Nanniazzi-Alaimo, L; Phillips, DR; Young, JJ	1
Batchelor, WB; Califf, RM; Cantor, WJ; Davidian, M; DiBattiste, PM; Dillard, P; Gretler, D; Harrington, RA; Huang, Y; Larsen, RL; Mantell, RM; Ohman, EM; Sketch, MH; Tcheng, JE; Tolleson, TR; Zhang, D; Zidar, JP	1
Grebe, M; Matzdorff, A; Pralle, H; Tillmanns, H; Voss, R	1

Reviews

1 review(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and tirofiban

Article	Year
Platelet aggregation inhibition with glycoprotein IIb--IIIa inhibitors. Journal of thrombosis and thrombolysis, 2001, Volume: 11, Issue:2 Topics: Abciximab; Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Anticoagulants; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Interactions; Eptifibatide; Heparin; Humans; Immunoglobulin Fab Fragments; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Proteins; Receptors, Thrombin; Thrombin; Tirofiban; Tyrosine	2001

Article

Year

Platelet aggregation inhibition with glycoprotein IIb--IIIa inhibitors.

Journal of thrombosis and thrombolysis, 2001, Volume: 11, Issue:2

Topics: Abciximab; Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Anticoagulants; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Interactions; Eptifibatide; Heparin; Humans; Immunoglobulin Fab Fragments; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Proteins; Receptors, Thrombin; Thrombin; Tirofiban; Tyrosine

2001

Trials

1 trial(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and tirofiban

Article	Year
Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, an Circulation, 2002, Sep-17, Volume: 106, Issue:12 Topics: Abciximab; Acute Disease; Aged; Amino Acid Chloromethyl Ketones; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Citric Acid; Coronary Disease; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Kinetics; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Syndrome; Tirofiban; Tyrosine	2002

Article

Year

Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, an

Circulation, 2002, Sep-17, Volume: 106, Issue:12

Topics: Abciximab; Acute Disease; Aged; Amino Acid Chloromethyl Ketones; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Citric Acid; Coronary Disease; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Kinetics; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Syndrome; Tirofiban; Tyrosine

2002

Other Studies

3 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and tirofiban

Article	Year
Estimation of anti-platelet drugs on human platelet aggregation with a novel whole blood aggregometer by a screen filtration pressure method. British journal of pharmacology, 2001, Volume: 133, Issue:8 Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Aspirin; Blood Coagulation; Blood Platelets; Cilostazol; Collagen; Dipyridamole; Filtration; Heparin; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Pressure; Tetrazoles; Time Factors; Tirofiban; Tyrosine	2001
Differential effects of citrate versus PPACK anticoagulation on measured platelet inhibition by abciximab, eptifibatide and tirofiban. Journal of thrombosis and thrombolysis, 2001, Volume: 12, Issue:2 Topics: Abciximab; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Blood Specimen Collection; Calcium; Chelating Agents; Citric Acid; Drug Interactions; Drug Monitoring; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tirofiban; Tyrosine	2001
Pharmacodynamics of two different dosing regimens of tirofiban in citrate or PPACK anticoagulated blood. Platelets, 2005, Volume: 16, Issue:8 Topics: Aged; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Platelets; Citric Acid; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tirofiban; Tyrosine	2005