phenylalanyl-prolyl-arginine-chloromethyl ketone and serine

phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with serine in 3 studies

Compound Research Comparison

Studies (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Trials (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Recent Studies (post-2010) (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Studies (serine)	Trials (serine)	Recent Studies (post-2010) (serine)
191	4	23	23,914	115	6,084

Protein Interaction Comparison

Protein	Taxonomy	phenylalanyl-prolyl-arginine-chloromethyl ketone (IC50)	serine (IC50)
Acetylcholinesterase	Electrophorus electricus (electric eel)		0.015
Cholinesterase	Equus caballus (horse)		0.016

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (33.33)	18.2507
2000's	1 (33.33)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chang, CY; Das, J; Malley, MF; Ohringer, SL; Roberts, DG; Sack, JS; Tabernero, L	1
Bode, C; Darius, H; Diehm, C; Encke, A; Gulba, DC; Haas, S; Hacke, W; Puhl, W; Quante, M; Riess, H; Scharf, R; Schellong, S; Schrör, T; Schulte, KL; Tebbe, U; Van Aken, H	1
Chen, Z; Di Cera, E; Gohara, DW; Pelc, LA; Pozzi, N; Vogt, AD	1

Reviews

1 review(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and serine

Article	Year
Anticoagulation: the present and future. Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3 Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis	2001

Article

Year

Anticoagulation: the present and future.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2001, Volume: 7, Issue:3

Topics: Administration, Oral; Amino Acid Chloromethyl Ketones; Anticoagulants; Arginine; Azetidines; Benzylamines; Binding Sites; Biological Availability; Blood Coagulation; Comorbidity; Coumarins; Drug Design; Embolism; Female; Forecasting; Glycine; Guanidines; Heart Diseases; Hemorrhage; Heparin; Heparin, Low-Molecular-Weight; Hirudin Therapy; Humans; Neoplasms; Pipecolic Acids; Pregnancy; Pregnancy Complications, Hematologic; Prodrugs; Safety; Serine; Stroke; Sulfonamides; Thrombin; Thrombophilia; Thrombosis

2001

Other Studies

2 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and serine

Article	Year
Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090. Protein science : a publication of the Protein Society, 1996, Volume: 5, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Guanidines; Humans; Models, Molecular; Molecular Sequence Data; Nipecotic Acids; Protein Binding; Protein Structure, Secondary; Serine; Thrombin	1996
Why Ser and not Thr brokers catalysis in the trypsin fold. Biochemistry, 2015, Feb-24, Volume: 54, Issue:7 Topics: Allosteric Regulation; Amino Acid Chloromethyl Ketones; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; HEK293 Cells; Humans; Models, Molecular; Point Mutation; Protein Conformation; Serine; Threonine; Thrombin; Trypsin	2015

Article

Year

Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.

Protein science : a publication of the Protein Society, 1996, Volume: 5, Issue:2

Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Binding Sites; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Guanidines; Humans; Models, Molecular; Molecular Sequence Data; Nipecotic Acids; Protein Binding; Protein Structure, Secondary; Serine; Thrombin

1996

Why Ser and not Thr brokers catalysis in the trypsin fold.

Biochemistry, 2015, Feb-24, Volume: 54, Issue:7

Topics: Allosteric Regulation; Amino Acid Chloromethyl Ketones; Amino Acid Substitution; Catalytic Domain; Crystallography, X-Ray; HEK293 Cells; Humans; Models, Molecular; Point Mutation; Protein Conformation; Serine; Threonine; Thrombin; Trypsin

2015