phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with piperidines in 7 studies
| Studies (phenylalanyl-prolyl-arginine-chloromethyl ketone) | Trials (phenylalanyl-prolyl-arginine-chloromethyl ketone) | Recent Studies (post-2010) (phenylalanyl-prolyl-arginine-chloromethyl ketone) | Studies (piperidines) | Trials (piperidines) | Recent Studies (post-2010) (piperidines) |
|---|---|---|---|---|---|
| 191 | 4 | 23 | 40,235 | 5,221 | 14,545 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banner, DW; Hadváry, P | 1 |
| Gustafson, GT; Lerner, UH | 1 |
| Grootenhuis, PD; Karplus, M | 1 |
| Deinum, J; Elg, M; Gustafsson, D | 1 |
| Fang, M; Fisher, LL; Kovács, KJ; Larson, AA | 1 |
| Frebelius, S; Grip, L; Linder, R; Swedenborg, J | 1 |
| Manallack, DT | 1 |
7 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and piperidines
| Article | Year |
|---|---|
Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
Topics: Amino Acid Chloromethyl Ketones; Antithrombins; Arginine; Benzamidines; Binding Sites; Dipeptides; Humans; Models, Molecular; Pipecolic Acids; Piperidines; Stereoisomerism; Sulfonamides; Thrombin; Trypsin | 1991 |
Inhibition of bone resorption in vitro by serine-esterase inhibitors.
Topics: Acetylglucosaminidase; Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Calcium; Esterases; Glucuronidase; Hydroxycholecalciferols; Hydroxyproline; L-Lactate Dehydrogenase; Mice; Organ Culture Techniques; Parathyroid Hormone; Phenylalanine; Phosphates; Piperidines | 1988 |
Functionality map analysis of the active site cleft of human thrombin.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Arginine; Binding Sites; Dipeptides; Humans; Models, Molecular; Molecular Probes; Molecular Sequence Data; Molecular Structure; Pipecolic Acids; Piperidines; Protein Conformation; Serine Proteinase Inhibitors; Software; Sulfonamides; Thrombin | 1996 |
The importance of enzyme inhibition kinetics for the effect of thrombin inhibitors in a rat model of arterial thrombosis.
Topics: Amino Acid Chloromethyl Ketones; Animals; Anticoagulants; Arginine; Azetidines; Benzylamines; Carotid Artery Thrombosis; Dose-Response Relationship, Drug; Fibrinolytic Agents; Glycine; Hemodynamics; Heparin; Hirudin Therapy; Hirudins; Kinetics; Male; Oligopeptides; Partial Thromboplastin Time; Peptide Fragments; Pipecolic Acids; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Sulfonamides; Thrombin; Thrombin Time | 1997 |
Thrombin inhibits NMDA-mediated nociceptive activity in the mouse: possible mediation by endothelin.
Topics: Acetic Acid; Amino Acid Chloromethyl Ketones; Animals; Behavior, Animal; Capillary Permeability; Endothelins; Evans Blue; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Intraperitoneal; Male; Mice; N-Methylaspartate; Nociceptors; Oligopeptides; Pain Measurement; Peptide Fragments; Peptides, Cyclic; Physical Stimulation; Piperidines; Reaction Time; Receptor, Endothelin A; Receptor, Endothelin B; Thrombin; Urea | 2003 |
The influence of direct and antithrombin-dependent thrombin inhibitors on the procoagulant and anticoagulant effects of thrombin.
Topics: Amino Acid Chloromethyl Ketones; Anticoagulants; Azetidines; Benzylamines; Clinical Trials as Topic; Coagulants; Coronary Artery Disease; Fibrinopeptide A; Glycine; Hirudins; Humans; Peptide Fragments; Piperidines; Protein C; Thrombin | 2003 |
The use of local surface properties for molecular superimposition.
Topics: Amino Acid Chloromethyl Ketones; Anti-HIV Agents; Anticoagulants; Antimetabolites, Antineoplastic; Crystallography, X-Ray; Dipeptides; Folic Acid; HIV Protease Inhibitors; Humans; Imidazoles; Ligands; Methotrexate; Models, Molecular; Molecular Structure; Piperidines; Protein Binding; Proteins; Quinoxalines; Reverse Transcriptase Inhibitors; Software; Static Electricity; Structure-Activity Relationship; Sulfur Compounds; Surface Properties; Tetrahydrofolate Dehydrogenase | 2008 |