phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with hirugen in 6 studies
| Studies (phenylalanyl-prolyl-arginine-chloromethyl ketone) | Trials (phenylalanyl-prolyl-arginine-chloromethyl ketone) | Recent Studies (post-2010) (phenylalanyl-prolyl-arginine-chloromethyl ketone) | Studies (hirugen) | Trials (hirugen) | Recent Studies (post-2010) (hirugen) |
|---|---|---|---|---|---|
| 191 | 4 | 23 | 50 | 0 | 4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Loscalzo, J; Scharfstein, J | 1 |
| Hirsh, J; Hudoba, M; Maraganore, J; Massel, D; Weitz, JI | 1 |
| Mann, KG; Padmanabhan, KP; Tulinsky, A; Vijayalakshmi, J | 1 |
| Chrusciel, RA; Kahn, M; Nakanishi, H; Priebe, C; Shen, R; Tulinsky, A; Wu, TP; Yee, V | 1 |
| Aleksic, I; Althaus, U; Gafner, V; Joch, H; Julmy, F; Lüscher, TF; Noll, G; Rabelink, TJ; Ruschitzka, F; Yang, Z | 1 |
| Frebelius, S; Grip, L; Linder, R; Swedenborg, J | 1 |
1 review(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and hirugen
| Article | Year |
|---|---|
Molecular approaches to antithrombotic therapy.
Topics: Amino Acid Chloromethyl Ketones; Antithrombins; Arginine; Heparin; Hirudins; Humans; Peptide Fragments; Pipecolic Acids; Protease Inhibitors; Sulfonamides; Thrombin; Warfarin | 1992 |
5 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and hirugen
| Article | Year |
|---|---|
Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.
Topics: Amino Acid Chloromethyl Ketones; Antithrombin III; Blood Coagulation; Fibrin; Fibrinopeptide A; Heparin; Hirudins; Humans; In Vitro Techniques; Kinetics; Peptide Fragments; Protease Inhibitors; Protein Binding; Solubility; Thrombin | 1990 |
The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Enzyme Precursors; Hirudins; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Protein Binding; Protein Conformation; Prothrombin; Thrombin | 1994 |
The structure of a designed peptidomimetic inhibitor complex of alpha-thrombin.
Topics: Amino Acid Chloromethyl Ketones; Azepines; Fibrinogen; Hirudins; Models, Molecular; Molecular Conformation; Oligopeptides; Peptide Fragments; Protein Conformation; Serine Proteinase Inhibitors; Substrate Specificity; Thrombin; X-Ray Diffraction | 1993 |
Different effects of thrombin receptor activation on endothelium and smooth muscle cells of human coronary bypass vessels. Implications for venous bypass graft failure.
Topics: Amino Acid Chloromethyl Ketones; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Coronary Artery Bypass; DNA Replication; Endothelium, Vascular; Enzyme Activation; Hirudin Therapy; Hirudins; Humans; Internal Mammary-Coronary Artery Anastomosis; Mitogen-Activated Protein Kinase 1; Muscle, Smooth, Vascular; Oligopeptides; Peptide Fragments; Phosphorylation; Prosthesis Failure; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Receptors, Thrombin; Saphenous Vein; Thrombin; Up-Regulation; Vasoconstriction | 1997 |
The influence of direct and antithrombin-dependent thrombin inhibitors on the procoagulant and anticoagulant effects of thrombin.
Topics: Amino Acid Chloromethyl Ketones; Anticoagulants; Azetidines; Benzylamines; Clinical Trials as Topic; Coagulants; Coronary Artery Disease; Fibrinopeptide A; Glycine; Hirudins; Humans; Peptide Fragments; Piperidines; Protein C; Thrombin | 2003 |