Compounds > phenylalanyl-prolyl-arginine-chloromethyl ketone

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phenylalanyl-prolyl-arginine-chloromethyl ketone and fibrinogen

phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with fibrinogen in 18 studies

Compound Research Comparison

Studies (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Trials (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Recent Studies (post-2010) (phenylalanyl-prolyl-arginine-chloromethyl ketone)	Studies (fibrinogen)	Trials (fibrinogen)	Recent Studies (post-2010) (fibrinogen)
191	4	23	34,477	1,707	7,083

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (33.33)	18.7374
1990's	9 (50.00)	18.2507
2000's	1 (5.56)	29.6817
2010's	2 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bode, W; Karshikov, A; Turk, D	1
Kaminski, M; Mosesson, MW; Siebenlist, KR	1
Kaminski, M; Mosesson, MW	1
Chen, AB; Chen, SA; Hotchkiss, AJ; Mohler, MA; Refino, CJ	1
Chen, AB; Collen, D; Hopkins, A; Stump, DC; Topol, EJ	1
Briston, C; Carlson, RW; Chilton, SM; Schaeffer, RC	1
Kaminski, M; McDonagh, J	1
Bode, AP; Miller, DT	1
Carlson, RW; Chilton, SM; Hadden, TJ; Schaeffer, RC	1
Bovill, EG; Cornell, ES; Geffken, DF; Keating, FG; Kennedy, MH; Tracy, RP	1
Connolly, TM; Gan, ZR; Lewis, SD; Li, Y; Sardana, MK; Shafer, JA; Tsai, PK	1
Chrusciel, RA; Kahn, M; Nakanishi, H; Priebe, C; Shen, R; Tulinsky, A; Wu, TP; Yee, V	1
Connolly, TM; Jenzano, JW; Lundblad, RL; Tsai, J; White, GC; Wu, HF	1
Bunce, LA; Francis, CW; Hamaguchi, M; Sporn, LA	1
Carpen, O; Lassila, R; Siljander, P	1
Brynda, E; Dyr, JE; Houska, M; Riedel, T	1
Malovichko, MV; Maurer, MC; Sabo, TM	1
Canino, J; Canobbio, I; Guidetti, GF; Torti, M; Visconte, C; Zarà, M	1

Trials

1 trial(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and fibrinogen

Article	Year
The measurement of fibrinogen in population-based research. Studies on instrumentation and methodology. Archives of pathology & laboratory medicine, 1994, Volume: 118, Issue:11 Topics: Amino Acid Chloromethyl Ketones; Anticoagulants; Antithrombins; Aprotinin; Blood Coagulation; Blood Coagulation Disorders; Blood Coagulation Tests; Edetic Acid; Fibrinogen; Humans	1994

Other Studies

17 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and fibrinogen

Article	Year
The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships. Protein science : a publication of the Protein Society, 1992, Volume: 1, Issue:4 Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antithrombins; Enzyme Activation; Fibrinogen; Heparin; Humans; Hydrogen Bonding; Models, Molecular; Molecular Sequence Data; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Salts; Sequence Homology, Amino Acid; Surface Properties; Thrombin; Water; X-Ray Diffraction	1992
Evidence for thrombin enhancement of fibrin polymerization that is independent of its catalytic activity. The Journal of laboratory and clinical medicine, 1991, Volume: 117, Issue:3 Topics: Amino Acid Chloromethyl Ketones; Blood Coagulation; Chromatography, High Pressure Liquid; Fibrin; Fibrinogen; Hirudins; Humans; Polymers; Thrombin	1991
The acceleratory effect of thrombin on fibrin clot assembly. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1990, Volume: 1, Issue:4-5 Topics: Amino Acid Chloromethyl Ketones; Blood Coagulation; Fibrin; Fibrinogen; Hirudins; Kinetics; Nephelometry and Turbidimetry; Polymers; Thrombin	1990
D-Phe-Pro-Arg-chloromethylketone: its potential use in inhibiting the formation of in vitro artifacts in blood collected during tissue-type plasminogen activator thrombolytic therapy. Thrombosis and haemostasis, 1986, Oct-21, Volume: 56, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Aprotinin; Blood Specimen Collection; Enzyme Activation; Fibrinogen; Fibrinolysin; Fibrinolytic Agents; Humans; Kinetics; Plasminogen; Recombinant Proteins; Thrombin; Tissue Plasminogen Activator	1986
Monitoring of hemostasis parameters during coronary thrombolysis with recombinant tissue-type plasminogen activator. Thrombosis and haemostasis, 1988, Apr-08, Volume: 59, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Aprotinin; Blood Specimen Collection; Citrates; Citric Acid; Fibrinogen; Fibrinolysis; Hemostasis; Humans; Myocardial Infarction; Tissue Plasminogen Activator	1988
Disseminated intravascular coagulation following Echis carinatus venom in dogs: effects of a synthetic thrombin inhibitor. The Journal of laboratory and clinical medicine, 1986, Volume: 107, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Animals; Disseminated Intravascular Coagulation; Dogs; Endopeptidases; Factor VIII; Factor XII; Fibrin; Fibrin Fibrinogen Degradation Products; Fibrinogen; Hemoglobins; Kinetics; Leukopenia; Partial Thromboplastin Time; Prothrombin; Thrombocytopenia; Viper Venoms	1986
Inhibited thrombins. Interactions with fibrinogen and fibrin. The Biochemical journal, 1987, Mar-15, Volume: 242, Issue:3 Topics: Amino Acid Chloromethyl Ketones; Arginine; Binding Sites; Chromatography, Affinity; Dansyl Compounds; Dipeptides; Fibrin; Fibrinogen; Fluorescent Dyes; Hirudins; Phenylmethylsulfonyl Fluoride; Protein Binding; Pyridoxal Phosphate; Thrombin	1987
Generation and degradation of fibrinopeptide A in stored platelet concentrate. Vox sanguinis, 1986, Volume: 51, Issue:3 Topics: Amino Acid Chloromethyl Ketones; Blood Platelets; Blood Preservation; Citrates; Fibrinogen; Fibrinopeptide A; Humans; Radioimmunoassay; Thrombin	1986
Pulmonary fibrin microembolism with Echis carinatus venom in dogs: effects of a synthetic thrombin inhibitor. Journal of applied physiology: respiratory, environmental and exercise physiology, 1984, Volume: 57, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Animals; Body Water; Disease Models, Animal; Dogs; Fibrin; Fibrinogen; Hemodynamics; Leukocyte Count; Lung; Platelet Count; Pulmonary Embolism; Respiration; Thrombin; Viper Venoms	1984
Importance of the Arg-Gly-Asp triplet in human thrombin for maintenance of structure and function. Archives of biochemistry and biophysics, 1993, Volume: 301, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Base Sequence; Catalysis; Circular Dichroism; Disulfides; Dose-Response Relationship, Drug; Fibrinogen; Hirudins; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligopeptides; Platelet Activation; Protein C; Protein Conformation; Receptors, Cell Surface; Receptors, Thrombin; Recombinant Proteins; Serotonin; Structure-Activity Relationship; Thrombin	1993
The structure of a designed peptidomimetic inhibitor complex of alpha-thrombin. Protein engineering, 1993, Volume: 6, Issue:5 Topics: Amino Acid Chloromethyl Ketones; Azepines; Fibrinogen; Hirudins; Models, Molecular; Molecular Conformation; Oligopeptides; Peptide Fragments; Protein Conformation; Serine Proteinase Inhibitors; Substrate Specificity; Thrombin; X-Ray Diffraction	1993
Hydrophobic affinity chromatography of human thrombin. Archives of biochemistry and biophysics, 1993, Volume: 302, Issue:1 Topics: Acetonitriles; Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Binding Sites; Chromatography, Affinity; Dansyl Compounds; Dioxanes; Fibrinogen; Heparin; Histidine; Humans; Molecular Sequence Data; Pyridoxal Phosphate; Thrombin	1993
Spreading of platelets on fibrin is mediated by the amino terminus of the beta chain including peptide beta 15-42. Blood, 1993, May-01, Volume: 81, Issue:9 Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antibodies, Monoclonal; Blood Platelets; Cell Movement; Electrophoresis, Polyacrylamide Gel; Fibrin; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; In Vitro Techniques; Molecular Sequence Data; Oligopeptides; Platelet Adhesiveness; Serotonin	1993
Platelet-derived microparticles associate with fibrin during thrombosis. Blood, 1996, Jun-01, Volume: 87, Issue:11 Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Biomarkers; Blood Coagulation; Blood Platelets; Calcimycin; Calcium; Collagen; Fibrin; Fibrinogen; Humans; Ionophores; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Molecular Sequence Data; Oligopeptides; P-Selectin; Perfusion; Platelet Glycoprotein GPIIb-IIIa Complex; Thrombin; Thrombosis; von Willebrand Factor	1996
Controlled preparation of thin fibrin films immobilized at solid surfaces. Journal of biomedical materials research. Part A, 2009, Volume: 88, Issue:2 Topics: Amino Acid Chloromethyl Ketones; Animals; Biocompatible Materials; Fibrin; Fibrinogen; Fibrinolytic Agents; Hirudins; Humans; Materials Testing; Methylmethacrylates; Polyhydroxyethyl Methacrylate; Porosity; Protease Inhibitors; Surface Properties; Swine; Thrombin; Tissue Scaffolds	2009
Ligand binding to anion-binding exosites regulates conformational properties of thrombin. The Journal of biological chemistry, 2013, Mar-22, Volume: 288, Issue:12 Topics: Amino Acid Chloromethyl Ketones; Animals; Anions; Binding Sites; Catalytic Domain; Cattle; Deuterium Exchange Measurement; Fibrinogen; Hirudins; Ligands; Membrane Glycoproteins; Models, Molecular; Peptide Fragments; Platelet Glycoprotein GPIb-IX Complex; Protein Binding; Receptors, Thrombin; Thrombin	2013
Molecular mechanisms of platelet activation and aggregation induced by breast cancer cells. Cellular signalling, 2018, Volume: 48 Topics: Amino Acid Chloromethyl Ketones; Aspirin; Blood Platelets; Breast Neoplasms; Caco-2 Cells; Calcium Chloride; Colorectal Neoplasms; Female; Fibrin; Fibrinogen; Humans; Integrin alpha2; MCF-7 Cells; Platelet Activation; Platelet Aggregation; Thromboxane A2; Type C Phospholipases	2018