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phenylalanyl-prolyl-arginine-chloromethyl ketone and citric acid, anhydrous

phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with citric acid, anhydrous in 9 studies

Compound Research Comparison

Studies
(phenylalanyl-prolyl-arginine-chloromethyl ketone)
Trials
(phenylalanyl-prolyl-arginine-chloromethyl ketone)
Recent Studies (post-2010)
(phenylalanyl-prolyl-arginine-chloromethyl ketone)
Studies
(citric acid, anhydrous)
Trials
(citric acid, anhydrous)
Recent Studies (post-2010) (citric acid, anhydrous)
19142311,8947834,366

Protein Interaction Comparison

ProteinTaxonomyphenylalanyl-prolyl-arginine-chloromethyl ketone (IC50)citric acid, anhydrous (IC50)
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
Chain A, Proto-oncogene Tyrosine-protein Kinase SrcHomo sapiens (human)40000
perilipin-5Homo sapiens (human)4.5885
perilipin-1Homo sapiens (human)3.708
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)4.5885

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's4 (44.44)18.2507
2000's4 (44.44)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giles, AR; Hoogendoorn, H; Nesheim, ME; Toh, CH1
Anderson, GM; Cohen, DJ; Horne, WC1
Chen, AB; Collen, D; Hopkins, A; Stump, DC; Topol, EJ1
Danielsen, D; Rahr, HB; Sørensen, JV1
Cattaneo, M; Falcon, CR; Ghidoni, A; Mannucci, PM1
Beer, JH; Lassila, R; Lepäntalo, A; Siljander, P; Syrjälä, M1
Kereiakes, DJ; Kukielka, G; Lorenz, T; Mueller, MN; Nanniazzi-Alaimo, L; Phillips, DR; Young, JJ1
Batchelor, WB; Califf, RM; Cantor, WJ; Davidian, M; DiBattiste, PM; Dillard, P; Gretler, D; Harrington, RA; Huang, Y; Larsen, RL; Mantell, RM; Ohman, EM; Sketch, MH; Tcheng, JE; Tolleson, TR; Zhang, D; Zidar, JP1
Grebe, M; Matzdorff, A; Pralle, H; Tillmanns, H; Voss, R1

Trials

1 trial(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and citric acid, anhydrous

ArticleYear
Randomized COMparison of platelet inhibition with abciximab, tiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison Of Measurements of Platelet aggregation with Aggrastat, Reopro, an
    Circulation, 2002, Sep-17, Volume: 106, Issue:12

    Topics: Abciximab; Acute Disease; Aged; Amino Acid Chloromethyl Ketones; Angina, Unstable; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Anticoagulants; Citric Acid; Coronary Disease; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Kinetics; Male; Middle Aged; Myocardial Infarction; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Syndrome; Tirofiban; Tyrosine

2002

Other Studies

8 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and citric acid, anhydrous

ArticleYear
Alpha 2-macroglobulin binds and inhibits activated protein C.
    Blood, 1991, Nov-01, Volume: 78, Issue:9

    Topics: alpha-Macroglobulins; Amino Acid Chloromethyl Ketones; Antithrombins; Binding Sites; Chemical Precipitation; Chromatography; Citrates; Citric Acid; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Humans; Immunoelectrophoresis; Kinetics; Methylamines; Protein C

1991
Reproducibility and temporal stability of ADP-induced platelet aggregation: comparison of the anticoagulants sodium citrate and D-phenylalanyl-L-prolyl-L-arginyl-chloromethyl ketone.
    American journal of hematology, 1991, Volume: 38, Issue:1

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Preservation; Citrates; Citric Acid; Humans; Osmolar Concentration; Platelet Aggregation; Reproducibility of Results; Time Factors

1991
Monitoring of hemostasis parameters during coronary thrombolysis with recombinant tissue-type plasminogen activator.
    Thrombosis and haemostasis, 1988, Apr-08, Volume: 59, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Aprotinin; Blood Specimen Collection; Citrates; Citric Acid; Fibrinogen; Fibrinolysis; Hemostasis; Humans; Myocardial Infarction; Tissue Plasminogen Activator

1988
Markers of coagulation and fibrinolysis in blood drawn into citrate with and without D-Phe-Pro-Arg-Chloromethylketone (PPACK).
    Thrombosis research, 1994, Mar-01, Volume: 73, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antithrombin III; Artifacts; Biomarkers; Blood Coagulation; Blood Specimen Collection; Citrates; Citric Acid; Fibrin Fibrinogen Degradation Products; Fibrinolysis; Humans; Immunoenzyme Techniques; Molecular Sequence Data; Peptide Fragments; Peptide Hydrolases; Postoperative Period; Prothrombin

1994
The in vitro production of thromboxane B2 by platelets of diabetic patients is normal at physiological concentrations of ionized calcium.
    Thrombosis and haemostasis, 1993, Sep-01, Volume: 70, Issue:3

    Topics: Adult; Amino Acid Chloromethyl Ketones; Anticoagulants; Antithrombins; Blood Platelets; Calcium; Citrates; Citric Acid; Diabetes Mellitus; Humans; In Vitro Techniques; Middle Aged; Platelet Count; Thromboxane B2

1993
Variability in platelet responses to collagen--comparison between whole blood perfusions, traditional platelet function tests and PFA-100.
    Thrombosis research, 2001, Jul-15, Volume: 103, Issue:2

    Topics: Adenosine Diphosphate; Adult; Aged; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Platelets; Citric Acid; Collagen; Drug Synergism; Epinephrine; Female; Genetic Variation; Humans; Integrins; Male; Middle Aged; Perfusion; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Polymorphism, Genetic; Receptors, Collagen; Reproducibility of Results; Rheology; Stress, Mechanical

2001
Differential effects of citrate versus PPACK anticoagulation on measured platelet inhibition by abciximab, eptifibatide and tirofiban.
    Journal of thrombosis and thrombolysis, 2001, Volume: 12, Issue:2

    Topics: Abciximab; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Anticoagulants; Antithrombins; Blood Specimen Collection; Calcium; Chelating Agents; Citric Acid; Drug Interactions; Drug Monitoring; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tirofiban; Tyrosine

2001
Pharmacodynamics of two different dosing regimens of tirofiban in citrate or PPACK anticoagulated blood.
    Platelets, 2005, Volume: 16, Issue:8

    Topics: Aged; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Platelets; Citric Acid; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Tirofiban; Tyrosine

2005