Page last updated: 2024-09-03

phenylalanyl-prolyl-arginine-chloromethyl ketone and adenosine diphosphate

phenylalanyl-prolyl-arginine-chloromethyl ketone has been researched along with adenosine diphosphate in 8 studies

Compound Research Comparison

Studies
(phenylalanyl-prolyl-arginine-chloromethyl ketone)
Trials
(phenylalanyl-prolyl-arginine-chloromethyl ketone)
Recent Studies (post-2010)
(phenylalanyl-prolyl-arginine-chloromethyl ketone)
Studies
(adenosine diphosphate)
Trials
(adenosine diphosphate)
Recent Studies (post-2010) (adenosine diphosphate)
19142323,9894983,114

Protein Interaction Comparison

ProteinTaxonomyphenylalanyl-prolyl-arginine-chloromethyl ketone (IC50)adenosine diphosphate (IC50)
Chain A, Kinesin-like protein KIF11Homo sapiens (human)0.45
Heat shock 70 kDa protein 1A Homo sapiens (human)0.5
Sensor protein kinase WalKStaphylococcus aureus7.189

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's1 (12.50)18.2507
2000's6 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, GM; Cohen, DJ; Horne, WC1
Kinlough-Rathbone, RL; Lalau Keraly, C; Mustard, JF; Packham, MA; Suzuki, H1
Faul, JD; Huang, J; Lucchesi, BR; Rebello, SS1
Proimos, G1
Beer, JH; Lassila, R; Lepäntalo, A; Siljander, P; Syrjälä, M1
Eisenberg, PR; Gretler, D; Harrington, RA; Jennings, LK; Joseph, DM; Kleiman, NS; Labinaz, M; Lincoff, AM; McDougal, MF; Potthoff, RF; Tardiff, BE; Vorchheimer, DA1
Ito, H; Kimura, Y; Ozeki, Y; Sudo, T1
Dokainish, H; Gonzales, R; Gonzalez, R; Lakkis, N; Patel, P1

Reviews

1 review(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and adenosine diphosphate

ArticleYear
Platelet aggregation inhibition with glycoprotein IIb--IIIa inhibitors.
    Journal of thrombosis and thrombolysis, 2001, Volume: 11, Issue:2

    Topics: Abciximab; Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Antibodies, Monoclonal; Anticoagulants; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Drug Interactions; Eptifibatide; Heparin; Humans; Immunoglobulin Fab Fragments; Oligopeptides; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Proteins; Receptors, Thrombin; Thrombin; Tirofiban; Tyrosine

2001

Trials

1 trial(s) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and adenosine diphosphate

ArticleYear
Pharmacodynamics and pharmacokinetics of eptifibatide in patients with acute coronary syndromes: prospective analysis from PURSUIT.
    Circulation, 2001, Jul-24, Volume: 104, Issue:4

    Topics: Adenosine Diphosphate; Aged; Amino Acid Chloromethyl Ketones; Angina, Unstable; Antithrombins; Coronary Disease; Eptifibatide; Female; Humans; Male; Middle Aged; Peptide Fragments; Peptides; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Thrombin; Time Factors

2001

Other Studies

6 other study(ies) available for phenylalanyl-prolyl-arginine-chloromethyl ketone and adenosine diphosphate

ArticleYear
Reproducibility and temporal stability of ADP-induced platelet aggregation: comparison of the anticoagulants sodium citrate and D-phenylalanyl-L-prolyl-L-arginyl-chloromethyl ketone.
    American journal of hematology, 1991, Volume: 38, Issue:1

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Preservation; Citrates; Citric Acid; Humans; Osmolar Concentration; Platelet Aggregation; Reproducibility of Results; Time Factors

1991
Conditions affecting the responses of human platelets to epinephrine.
    Thrombosis and haemostasis, 1988, Oct-31, Volume: 60, Issue:2

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Antithrombins; Blood Platelets; Calcium; Drug Synergism; Epinephrine; Hirudins; Humans; Microscopy, Electron, Scanning; Platelet Aggregation

1988
Role of extracellular ionized calcium in the in vitro assessment of GPIIb/IIIa receptor antagonists.
    Journal of thrombosis and thrombolysis, 2000, Volume: 9, Issue:1

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Anticoagulants; Antithrombins; Calcium; Chelating Agents; Citrates; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Sodium Citrate

2000
Variability in platelet responses to collagen--comparison between whole blood perfusions, traditional platelet function tests and PFA-100.
    Thrombosis research, 2001, Jul-15, Volume: 103, Issue:2

    Topics: Adenosine Diphosphate; Adult; Aged; Amino Acid Chloromethyl Ketones; Anticoagulants; Blood Platelets; Citric Acid; Collagen; Drug Synergism; Epinephrine; Female; Genetic Variation; Humans; Integrins; Male; Middle Aged; Perfusion; Platelet Activation; Platelet Aggregation; Platelet Function Tests; Polymorphism, Genetic; Receptors, Collagen; Reproducibility of Results; Rheology; Stress, Mechanical

2001
Estimation of anti-platelet drugs on human platelet aggregation with a novel whole blood aggregometer by a screen filtration pressure method.
    British journal of pharmacology, 2001, Volume: 133, Issue:8

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Aspirin; Blood Coagulation; Blood Platelets; Cilostazol; Collagen; Dipyridamole; Filtration; Heparin; Humans; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Count; Platelet Function Tests; Pressure; Tetrazoles; Time Factors; Tirofiban; Tyrosine

2001
Impact of adenosine diphosphate and calcium chelation on platelet aggregation testing in patients receiving clopidogrel therapy.
    Journal of the American College of Cardiology, 2006, Jan-17, Volume: 47, Issue:2

    Topics: Adenosine Diphosphate; Amino Acid Chloromethyl Ketones; Chelating Agents; Citrates; Clopidogrel; Coronary Disease; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Sodium Citrate; Ticlopidine

2006