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phenylalanyl-phenylalanyl-arginine chloromethyl ketone and thromboplastin

phenylalanyl-phenylalanyl-arginine chloromethyl ketone has been researched along with thromboplastin in 13 studies

Compound Research Comparison

Studies
(phenylalanyl-phenylalanyl-arginine chloromethyl ketone)
Trials
(phenylalanyl-phenylalanyl-arginine chloromethyl ketone)
Recent Studies (post-2010)
(phenylalanyl-phenylalanyl-arginine chloromethyl ketone)
Studies
(thromboplastin)
Trials
(thromboplastin)
Recent Studies (post-2010) (thromboplastin)
260210,5402812,126

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (46.15)18.2507
2000's6 (46.15)29.6817
2010's1 (7.69)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guha, A; Konigsberg, WH; Laue, TM; Lin, TC; Nemerson, Y; Ross, JB; Thiruvikraman, SV; Waxman, E1
Jesty, J; Lorenz, A; Rodriguez, J; Wun, TC1
Ezban, M; Freskgârd, PO; Kjalke, M; Persson, E; Rao, LV; Sorensen, BB; Williams, T1
Ezban, M; Hedner, U; Hoffman, M; Kjalke, M; Monroe, DM; Oliver, JA; Roberts, HR2
St Charles, R; Tulinsky, A; Zhang, E1
Botticella, F; Buono, C; Chiariello, M; Cirillo, P; Condorelli, M; Ezban, M; Golino, P; Guarino, A; Lambiase, C; Piro, O; Ragni, M; Ravera, A; Scognamiglio, A1
Freskgård, PO; Nielsen, LS; Olsen, OH; Persson, E; Petersen, LC1
Ezban, M; Heldin, CH; Johnell, M; Rönnstrand, L; Rorsman, C; Siegbahn, A1
Carlsson, K; Carlsson, U; Freskgård, PO; Lindgren, M; Osterlund, M; Owenius, R; Persson, E; Svensson, M1
Petersen, LC1
Liotta, DC; Lu, YJ; Shoji, M; Snyder, JP; Sun, A1
Brat, DJ; El-Rayes, BF; Kisiel, W; Liotta, DC; Lu, YJ; Moore, TW; Ndungu, JM; Parker, ET; Petersen, LC; Sarkaria, JN; Shoji, M; Snyder, JP; Sun, A; Zhu, S1

Reviews

2 review(s) available for phenylalanyl-phenylalanyl-arginine chloromethyl ketone and thromboplastin

ArticleYear
The effects of activated factor VII in a cell-based model for tissue factor-initiated coagulation.
    Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis, 1998, Volume: 9 Suppl 1

    Topics: Amino Acid Chloromethyl Ketones; Blood Coagulation; Factor VIIa; Humans; Models, Biological; Monocytes; Platelet Activation; Serine Proteinase Inhibitors; Thromboplastin

1998
Active site-inhibited seven: mechanism of action including signal transduction.
    Seminars in hematology, 2001, Volume: 38, Issue:4 Suppl 12

    Topics: Amino Acid Chloromethyl Ketones; Binding Sites; Factor VIIa; Gene Expression Regulation; Humans; Serine Proteinase Inhibitors; Signal Transduction; Thromboplastin

2001

Other Studies

11 other study(ies) available for phenylalanyl-phenylalanyl-arginine chloromethyl ketone and thromboplastin

ArticleYear
Tissue factor and its extracellular soluble domain: the relationship between intermolecular association with factor VIIa and enzymatic activity of the complex.
    Biochemistry, 1992, Apr-28, Volume: 31, Issue:16

    Topics: Amino Acid Chloromethyl Ketones; Binding Sites; Dansyl Compounds; Factor VIIa; Fluorescence Polarization; Liposomes; Phosphatidylcholines; Solubility; Structure-Activity Relationship; Thromboplastin; Ultracentrifugation

1992
Initiation of the tissue factor pathway of coagulation in the presence of heparin: control by antithrombin III and tissue factor pathway inhibitor.
    Blood, 1996, Mar-15, Volume: 87, Issue:6

    Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Antithrombin III; Blood Coagulation; Chromogenic Compounds; Dansyl Compounds; Enzyme Activation; Factor VIIa; Factor X; Heparin; Humans; Lipoproteins; Recombinant Proteins; Thromboplastin

1996
Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor.
    The Journal of biological chemistry, 1997, May-02, Volume: 272, Issue:18

    Topics: Amino Acid Chloromethyl Ketones; Binding Sites; Binding, Competitive; Cell Line; Cell Membrane; Circular Dichroism; Factor VIIa; Fibrin; Humans; Kinetics; Protein Conformation; Recombinant Proteins; Thromboplastin; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1997
The effect of active site-inhibited factor VIIa on tissue factor-initiated coagulation using platelets before and after aspirin administration.
    Thrombosis and haemostasis, 1997, Volume: 78, Issue:4

    Topics: Adult; Amino Acid Chloromethyl Ketones; Aspirin; Binding Sites; Binding, Competitive; Blood Coagulation; Blood Platelets; Calcium; Cells, Cultured; Cyclooxygenase Inhibitors; Drug Administration Schedule; Drug Interactions; Factor VII; Factor VIIa; Fibrinolytic Agents; Humans; Kinetics; Lipopolysaccharides; Monocytes; P-Selectin; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Binding; Recombinant Proteins; Serine Proteinase Inhibitors; Thrombin; Thromboplastin

1997
Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.
    Journal of molecular biology, 1999, Feb-05, Volume: 285, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Amino Acid Sequence; Aprotinin; Catalytic Domain; Crystallography, X-Ray; Epidermal Growth Factor; Factor IXa; Factor VIIa; Models, Molecular; Molecular Sequence Data; Mutation; Protein Conformation; Sequence Homology, Amino Acid; Serine Proteinase Inhibitors; Thromboplastin

1999
Recombinant human, active site-blocked factor VIIa reduces infarct size and no-reflow phenomenon in rabbits.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Animals; Binding Sites; Blood Coagulation; Blood Platelets; Coronary Circulation; Factor VIIa; Fibrinogen; Hemodynamics; Hemostatics; Humans; Myocardial Infarction; Myocardial Reperfusion Injury; Rabbits; Recombinant Proteins; Thromboplastin

2000
Binding of Zn2+ to a Ca2+ loop allosterically attenuates the activity of factor VIIa and reduces its affinity for tissue factor.
    Protein science : a publication of the Protein Society, 2000, Volume: 9, Issue:5

    Topics: Alanine; Allosteric Site; Amino Acid Chloromethyl Ketones; Binding Sites; Calcium; Catalytic Domain; Dose-Response Relationship, Drug; Factor VIIa; Histidine; Humans; Ions; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Surface Plasmon Resonance; Thromboplastin; Time Factors; Zinc

2000
Binding of factor VIIa to tissue factor on human fibroblasts leads to activation of phospholipase C and enhanced PDGF-BB-stimulated chemotaxis.
    Blood, 2000, Nov-15, Volume: 96, Issue:10

    Topics: Amino Acid Chloromethyl Ketones; Becaplermin; Binding Sites; Cells, Cultured; Chemotaxis; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Factor VIIa; Factor Xa; Fibroblasts; Humans; Isoenzymes; Muscle, Smooth, Vascular; Phospholipase C gamma; Phosphorylation; Platelet-Derived Growth Factor; Protein Binding; Proto-Oncogene Proteins c-sis; Serine Proteinase Inhibitors; Signal Transduction; Thrombin; Thromboplastin; Type C Phospholipases

2000
Probing inhibitor-induced conformational changes along the interface between tissue factor and factor VIIa.
    Biochemistry, 2001, Aug-07, Volume: 40, Issue:31

    Topics: Amino Acid Chloromethyl Ketones; Anticoagulants; Binding Sites; Electron Spin Resonance Spectroscopy; Factor VIIa; Fluorescent Dyes; Mutagenesis, Site-Directed; Naphthalenesulfonates; Protein Binding; Protein Conformation; Serine Proteinase Inhibitors; Solubility; Spectrometry, Fluorescence; Spin Labels; Sulfhydryl Reagents; Thromboplastin

2001
Synthesis of EF24-tripeptide chloromethyl ketone: a novel curcumin-related anticancer drug delivery system.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Drug Delivery Systems; Drug Screening Assays, Antitumor; Factor VIIa; Humans; Models, Molecular; Oxidation-Reduction; Thromboplastin

2006
Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody.
    Journal of drug targeting, 2015, Volume: 23, Issue:3

    Topics: Amino Acid Chloromethyl Ketones; Animals; Carbocyanines; Cells, Cultured; Factor VIIa; Heterografts; Humans; Mice; Neoplasms; Optical Imaging; Paclitaxel; Thromboplastin

2015