Compounds > phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide
Page last updated: 2024-09-03

phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide and enkephalin, d-penicillamine (2,5)-

phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide has been researched along with enkephalin, d-penicillamine (2,5)- in 4 studies

Compound Research Comparison

Studies
(phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide)		Trials
(phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide)		Recent Studies (post-2010)
(phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide)		Studies
(enkephalin, d-penicillamine (2,5)-)		Trials
(enkephalin, d-penicillamine (2,5)-)		Recent Studies (post-2010) (enkephalin, d-penicillamine (2,5)-)
2760551,314073
7051,314073

Protein Interaction Comparison

ProteinTaxonomyphenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide (IC50)enkephalin, d-penicillamine (2,5)- (IC50)
Mu-type opioid receptorHomo sapiens (human)0.0016
Delta-type opioid receptorHomo sapiens (human)0.0011

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Maier, SF; Mooney-Heiberger, K; Watkins, LR; Wiertelak, EP; Yang, HY1
Gouardères, C; Jhamandas, K; Sutak, M; Zajac, JM1
Bihel, F; Drieu la Rochelle, A; Elhabazi, K; Gizzi, P; Henningsen, JB; Ilien, B; Kugler, V; Quillet, R; Schmitt, M; Schneider, S; Simonin, F; Simonneaux, V; Utard, V1
Chen, D; Fang, Q; Li, N; Niu, J; Shi, X; Shi, Y; Xiao, J; Xu, B; Xu, K; Zhang, M; Zhang, Q; Zhang, R1

Other Studies

4 other study(ies) available for phenylalanyl-leucyl-phenylalanyl-glutaminyl-prolyl-glutaminyl-arginyl-phenylalaninamide and enkephalin, d-penicillamine (2,5)-

ArticleYear
The nature of conditioned anti-analgesia: spinal cord opiate and anti-opiate neurochemistry.
    Brain research, 1994, Jan-21, Volume: 634, Issue:2

    Topics: Analgesia; Analgesics; Animals; Conditioning, Classical; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Immune Sera; Injections, Spinal; Male; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Proglumide; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord

1994
Role of opioid receptors in the spinal antinociceptive effects of neuropeptide FF analogues.
    British journal of pharmacology, 1996, Volume: 117, Issue:3

    Topics: Amino Acid Sequence; Analgesics; Analgesics, Opioid; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Molecular Sequence Data; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Spinal Cord

1996
Identification of an
    Journal of medicinal chemistry, 2021, 06-10, Volume: 64, Issue:11

    Topics: Analgesics, Opioid; Animals; Cricetinae; Dipeptides; Female; Fentanyl; Half-Life; Humans; Hyperalgesia; Luteinizing Hormone; Male; Mice; Mice, Inbred C57BL; Neuropeptides; Protein Isoforms; Receptors, Neuropeptide; Receptors, Opioid; Structure-Activity Relationship

2021
Development of Multifunctional and Orally Active Cyclic Peptide Agonists of Opioid/Neuropeptide FF Receptors that Produce Potent, Long-Lasting, and Peripherally Restricted Antinociception with Diminished Side Effects.
    Journal of medicinal chemistry, 2021, 09-23, Volume: 64, Issue:18

    Topics: Analgesics, Opioid; Animals; Ligands; Male; Mice; Neuralgia; Peptides, Cyclic; Receptors, Neuropeptide

2021