phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide has been researched along with naloxone in 60 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.00) | 18.7374 |
| 1990's | 20 (33.33) | 18.2507 |
| 2000's | 22 (36.67) | 29.6817 |
| 2010's | 13 (21.67) | 24.3611 |
| 2020's | 2 (3.33) | 2.80 |
| Authors | Studies |
|---|---|
| Baumeister, AA; Hurry, MJ; Richard, AL; Richmond-Landeche, L; Waguespack, AM | 1 |
| Duckles, SP; Li, YJ | 1 |
| Gramsch, C; Hassan, AH; Herz, A; Parsons, CG; Peter, K; Przewlocki, R; Stein, C | 1 |
| Kromer, W | 2 |
| Bals-Kubik, R; Herz, A; Shippenberg, TS | 1 |
| Gulya, K; Hruby, VJ; Pelton, JT; Yamamura, HI | 1 |
| Gulya, K; Hruby, VJ; Kazmierski, W; Lui, GK; Pelton, JT; Yamamura, HI | 1 |
| Aoki, Y; Katao, Y; Katsumata, S; Minami, M; Nakagawa, T; Onogi, T; Satoh, M | 1 |
| Garzón, J; Martínez-Peña, Y; Sánchez-Blázquez, P | 1 |
| Elliott, J; Lambert, DG; Smart, D; Traynor, JR | 1 |
| Búzás, B; Cox, BM; Izenwasser, S | 1 |
| North, RA; Tanaka, E | 1 |
| Gozariu, L; Gozariu, MS; Orbai, P; Sandor, V; Schmidt-Gayk, H | 1 |
| Carter, L; Schäfer, M; Stein, C | 1 |
| North, RA; Sugita, S | 1 |
| Bernstein, RN; Bilsky, EJ; Porreca, F; Sadée, W; Wang, Z | 1 |
| Chieng, B; Christie, MJ; Connor, M | 1 |
| Fields, HL; Roychowdhury, SM | 1 |
| Bair, KD; Fowler, BM; Hernández, LL; Singha, AK; Watson, KL | 1 |
| Budai, D; Fields, HL | 1 |
| Chavkin, C; Jin, W | 1 |
| Ang, KK; Arnolda, LF; Chalmers, JP; Llewellyn-Smith, IJ; McRitchie, RJ; Minson, JB; Pilowsky, PM | 1 |
| Ali, A; Mason, R; Mundey, MK; Wilson, VG | 1 |
| Lutfy, K; Maidment, NT | 1 |
| Hyytiä, P; Kiianmaa, K | 1 |
| Cao, CQ; Dray, A; Hong, Y; Perkins, M | 1 |
| Bot, G; Chesselet, MF; Mehta, A; Reisine, T | 1 |
| Acosta-Martinez, M; Etgen, AM | 1 |
| McCormick, SE; Stoessl, AJ | 1 |
| García-Barrado, MJ; Iglesias-Osma, MC; Martín, M; Moratinos, J; Rodríguez, R | 1 |
| Brecha, NC; Kohlmeier, SE; Minnis, JG; Patierno, S; Sternini, C; Tonini, M | 1 |
| Maidment, NT; Skoubis, PD | 1 |
| Bennett, L; Ratka, A | 1 |
| Cadet, P; Pryor, SC; Putnam, J; Stefano, GB; Zhu, W | 1 |
| Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Suzuki, T; Takada, K | 1 |
| Hoo, N; Pryor, SC; Putnam, J | 1 |
| Aono, Y; Cools, AR; Koshikawa, N; Okutsu, H; Saigusa, T; Takahashi, I; Watanabe, S | 1 |
| Liu, AM; Wong, YH | 1 |
| Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Oi, Y; Suzuki, T; Takada, K | 1 |
| Aragon, CM; Pastor, R | 1 |
| Back, SK; Hong, SK; Lee, J; Na, HS | 1 |
| Mizoguchi, H; Nakayama, D; Sakurada, S; Sakurada, T; Watanabe, C; Watanabe, H | 1 |
| Ahn, DK; Han, SR; Jeon, HJ; Ju, JS; Kim, SK; Lee, MK; Lim, KH; Yang, GY; Yoon, YW | 1 |
| Spear, LP; Varlinskaya, EI | 1 |
| Bartolini, A; Bergonzi, MC; Bilia, AR; Galeotti, N; Ghelardini, C; Vivoli, E | 1 |
| Baker, JE; Falck, JR; Gross, GJ; Hsu, A; Nithipatikom, K; Wu, HE | 1 |
| Choi, JI; Kim, CM; Kim, KS; Kim, WM; Kim, YO; Lee, HG; Yoon, MH | 1 |
| Derrick, BE; Do, VH; Martinez, CO | 1 |
| Drdla-Schutting, R; Heinl, C; Sandkühler, J; Xanthos, DN | 1 |
| Benrath, J; Drdla-Schutting, R; Sandkühler, J; Wunderbaldinger, G | 1 |
| Prado, WA; Silva, JR; Silva, ML | 1 |
| Kozlov, AP; Kramskaya, TA; Nizhnikov, ME; Spear, NE; Varlinskaya, EI | 1 |
| Duffy, AM; Harte-Hargrove, LC; Milner, TA; Scharfman, HE; Varga-Wesson, A | 1 |
| Fanton, LE; Fischer, L; Macedo, CG; Tambeli, CH | 1 |
| Audi, EA; Coimbra, NC; Frias, AT; Graeff, FG; Roncon, CM; Yamashita, PSM; Zangrossi, H | 1 |
| Almada, RC; Biagioni, AF; Coimbra, NC; da Silva, JA; de Freitas, RL | 1 |
| Kvachadze, I; Tsagareli, M; Tsagareli, N; Tsiklauri, N | 1 |
| Bassani da Silva, B; Fernandes Magalhães, S; Gonçalves Dos Santos, G; Parada, CA; Tambeli, CH; Vendramini, PH; Vieira, WF | 1 |
| Kvachadze, I; Tsagareli, MG; Tsagareli, N; Tsiklauri, N | 1 |
60 other study(ies) available for phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and naloxone
| Article | Year |
|---|---|
Further studies of the role of opioid receptors in the nigra in the morphine withdrawal syndrome.
Topics: Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Body Temperature; Brain; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Molecular Sequence Data; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Stereotaxic Techniques; Substance Withdrawal Syndrome; Substantia Nigra | 1992 |
Effect of opioid receptor antagonists on vasodilator nerve actions in the perfused rat mesentery.
Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanethidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Vasodilation | 1991 |
Local opioid receptors mediating antinociception in inflammation: endogenous ligands.
Topics: Animals; Endorphins; Enkephalin, Leucine; Inflammation; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 1990 |
Reflex peristalsis in the guinea pig isolated ileum is endogenously controlled by kappa opioid receptors.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peristalsis; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Somatostatin | 1990 |
Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Brain; Conditioning, Operant; Enkephalin, Leucine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Somatostatin | 1989 |
Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors.
Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Receptors, Somatostatin; Somatostatin; Structure-Activity Relationship | 1986 |
H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2: a potent and selective antagonist opioid receptors.
Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Kinetics; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 1986 |
DAMGO, a mu-opioid receptor selective ligand, distinguishes between mu-and kappa-opioid receptors at a different region from that for the distinction between mu- and delta-opioid receptors.
Topics: Amino Acid Sequence; Analgesics; Animals; Cells, Cultured; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ligands; Molecular Sequence Data; Morphine; Naloxone; Oligopeptides; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Somatostatin; Structure-Activity Relationship | 1995 |
Unexpected prosecretory action component of loperamide at mu-opioid receptors in the guinea-pig colonic mucosa in vitro.
Topics: Alprostadil; Amino Acid Sequence; Animals; Chlorides; Colon; Dose-Response Relationship, Drug; Ethylketocyclazocine; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Molecular Sequence Data; Naloxone; Naltrexone; Patch-Clamp Techniques; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Theophylline | 1995 |
G-receptor antagonists increased the activating effect of mastoparan on low Km GTPase of mouse PAG.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Kinetics; Male; Mice; Naloxone; Peptides; Periaqueductal Gray; Receptors, Cell Surface; Somatostatin; Wasp Venoms | 1995 |
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured | 1994 |
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin | 1993 |
Opioid actions on rat anterior cingulate cortex neurons in vitro.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Glutamates; Glutamic Acid; Gyrus Cinguli; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Neurotransmitter Agents; Rats; Receptors, Opioid; Somatostatin; Synapses; Synaptic Transmission | 1994 |
The mechanism involved in the central effect of 5-leu enkephalin on the calcitonin secretion.
Topics: Animals; Calcitonin; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Naloxone; Narcotic Antagonists; Oxidopamine; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Sympathectomy, Chemical; Thyroid Gland | 1993 |
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue.
Topics: Analysis of Variance; Animals; Antibodies; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclosporine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Inflammation; Injections; Interleukin-1; Male; Naloxone; Pain; Rats; Rats, Wistar; Recombinant Proteins; Regression Analysis; Somatostatin | 1994 |
Opioid actions on neurons of rat lateral amygdala in vitro.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Amino Acids; Amygdala; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; GABA-A Receptor Antagonists; In Vitro Techniques; Molecular Sequence Data; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Pyrrolidines; Rats; Somatostatin; Synapses | 1993 |
Effects of naloxone and D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 and the protein kinase inhibitors H7 and H8 on acute morphine dependence and antinociceptive tolerance in mice.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Sequence; Analgesics, Opioid; Animals; Drug Tolerance; Enzyme Inhibitors; Isoquinolines; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Peptide Fragments; Peptides; Piperazines; Protein Kinase C; Receptors, Opioid, mu; Somatostatin | 1996 |
The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.
Topics: Animals; Brimonidine Tartrate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Naloxone; Narcotics; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Peptides; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 1996 |
Endogenous opioids acting at a medullary mu-opioid receptor contribute to the behavioral antinociception produced by GABA antagonism in the midbrain periaqueductal gray.
Topics: Animals; Bicuculline; Brain Mapping; GABA Antagonists; Male; Medulla Oblongata; Mesencephalon; Microinjections; Models, Neurological; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Time Factors | 1996 |
Opioid modulation of attention-related responses: peripheral-to-central progression and development of mu influence as learning occurs.
Topics: Animals; Conditioning, Classical; Female; Heart Rate; Male; Naloxone; Narcotic Antagonists; Quaternary Ammonium Compounds; Rabbits; Receptors, Opioid, mu; Somatostatin | 1997 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 1999 |
Activation of spinal opioid receptors contributes to hypotension after hemorrhage in conscious rats.
Topics: Animals; Blood Pressure; Consciousness; Dynorphins; Endorphins; Enkephalin, Leucine; Heart Rate; Hemorrhage; Hypotension; Male; Naloxone; Narcotic Antagonists; Neural Inhibition; Rats; Rats, Inbred WKY; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Sympathetic Nervous System | 1999 |
Pharmacological examination of contractile responses of the guinea-pig isolated ileum produced by mu-opioid receptor antagonists in the presence of, and following exposure to, morphine.
Topics: Animals; Benzomorphans; Guinea Pigs; Ileum; In Vitro Techniques; Male; Morphine; Muscle Contraction; Naloxone; Narcotic Antagonists; Peptide Fragments; Peptides; Phentolamine; Receptors, Opioid, mu; Somatostatin | 2000 |
Blockade of mu-opioid receptors reveals the hyperalgesic effect of orphanin FQ/nociceptin in the rat hot plate test.
Topics: Animals; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptin; Opioid Peptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid, mu; Somatostatin | 2000 |
Suppression of ethanol responding by centrally administered CTOP and naltrindole in AA and Wistar rats.
Topics: Alcohol Drinking; Amygdala; Animals; Central Nervous System Depressants; Conditioning, Operant; Ethanol; Genotype; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Self Administration; Somatostatin | 2001 |
Spinal delta-opioid receptors mediate suppression of systemic SNC80 on excitability of the flexor reflex in normal and inflamed rat.
Topics: Afferent Pathways; Animals; Benzamides; Central Nervous System; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Hypersensitivity; Electric Stimulation; Electrophysiology; Freund's Adjuvant; Hindlimb; Indoles; Inflammation; Male; Morphinans; Motor Neurons; Naloxone; Narcotic Antagonists; Pain Measurement; Piperazines; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Reflex; Somatostatin; Tartrates; Touch | 2001 |
Endomorphin-1: induction of motor behavior and lack of receptor desensitization.
Topics: Animals; Behavior, Animal; Catalepsy; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Administration Routes; Dyskinesia, Drug-Induced; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Globus Pallidus; Humans; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Oligopeptides; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Transfection | 2001 |
Activation of mu-opioid receptors inhibits lordosis behavior in estrogen and progesterone-primed female rats.
Topics: Analgesics, Opioid; Animals; Brain Chemistry; Diagonal Band of Broca; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Estrogens; Female; Injections, Intraventricular; Naloxone; Narcotic Antagonists; Oligopeptides; Posture; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sexual Behavior, Animal; Somatostatin; Ventromedial Hypothalamic Nucleus | 2002 |
Blockade of nigral and pallidal opioid receptors suppresses vacuous chewing movements in a rodent model of tardive dyskinesia.
Topics: Animals; Dose-Response Relationship, Drug; Dynorphins; Dyskinesia, Drug-Induced; Fluphenazine; Globus Pallidus; Male; Mastication; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Substantia Nigra | 2002 |
Role of mu-opioid receptors in insulin release in the presence of inhibitory and excitatory secretagogues.
Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Brimonidine Tartrate; Clonidine; Drug Interactions; Female; Glyburide; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Naloxone; Quinoxalines; Receptors, Opioid, mu; Somatostatin | 2002 |
Ligand-induced mu opioid receptor endocytosis and recycling in enteric neurons.
Topics: Analgesics, Opioid; Animals; Arsenicals; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Guinea Pigs; Ileum; Immunohistochemistry; Ligands; Microscopy, Confocal; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Potassium; Receptors, Opioid, mu; Somatostatin; Sucrose; Time Factors | 2003 |
Blockade of ventral pallidal opioid receptors induces a conditioned place aversion and attenuates acquisition of cocaine place preference in the rat.
Topics: Analysis of Variance; Animals; Cocaine; Conditioning, Operant; Dose-Response Relationship, Drug; Drug Interactions; Habituation, Psychophysiologic; Male; Motor Activity; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2003 |
Delta opioid receptors are involved in morphine-induced inhibition of luteinizing hormone releasing hormone in SK-N-SH cells.
Topics: Analgesics, Opioid; Cell Line, Tumor; Dose-Response Relationship, Drug; Gonadotropin-Releasing Hormone; Humans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neuroblastoma; Receptors, Opioid, delta; Somatostatin | 2003 |
Opiate alkaloids and nitric oxide production in the nematode Ascaris suum.
Topics: Animals; Ascaris suum; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Female; Male; Morphine; Morphine Derivatives; Muscles; Naloxone; Narcotic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Sex Characteristics; Somatostatin; Tissue Distribution | 2004 |
Deltorphin II enhances extracellular levels of dopamine in the nucleus accumbens via opioid receptor-independent mechanisms.
Topics: Analysis of Variance; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Tetrodotoxin; Time Factors | 2004 |
Opiate alkaloids in Ascaris suum.
Topics: Alkaloids; Analgesics, Opioid; Animals; Ascaris suum; Chromatography, High Pressure Liquid; DNA Primers; Electrochemistry; Female; Fluorescent Antibody Technique, Indirect; Gas Chromatography-Mass Spectrometry; Humans; Male; Morphine; Morphine Derivatives; Naloxone; Narcotic Antagonists; Narcotics; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors; Somatostatin; Time Factors; Tissue Distribution; Uterus | 2004 |
Endomorphin-2 and endomorphin-1 promote the extracellular amount of accumbal dopamine via nonopioid and mu-opioid receptors, respectively.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Behavior, Animal; Brain Chemistry; Dialysis; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Extracellular Space; Male; Naloxone; Narcotic Antagonists; Nucleus Accumbens; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin; Wakefulness | 2006 |
Mu-opioid receptor-mediated phosphorylation of IkappaB kinase in human neuroblastoma SH-SY5Y cells.
Topics: Analgesics, Opioid; Analysis of Variance; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; eIF-2 Kinase; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Naloxone; Narcotic Antagonists; Neuroblastoma; Pertussis Toxin; Phosphorylation; Receptors, Opioid, mu; Somatostatin; Time Factors | 2005 |
Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin | 2005 |
The role of opioid receptor subtypes in the development of behavioral sensitization to ethanol.
Topics: Analysis of Variance; Animals; Behavior, Animal; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Receptors, Opioid; Somatostatin; Time Factors | 2006 |
Loss of spinal mu-opioid receptor is associated with mechanical allodynia in a rat model of peripheral neuropathy.
Topics: Amino Acid Sequence; Animals; Axotomy; Disease Models, Animal; Hyperalgesia; Injections, Intraperitoneal; Injections, Spinal; Male; Molecular Sequence Data; Naloxone; Narcotic Antagonists; Neuralgia; Posterior Horn Cells; Pressure; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Spinal Nerves; Stress, Mechanical; Tail | 2006 |
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hot Temperature; Injections, Intraventricular; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Reaction Time; Receptors, Opioid, mu; Somatostatin; Time Factors | 2007 |
Intramuscular administration of morphine reduces mustard-oil-induced craniofacial-muscle pain behavior in lightly anesthetized rats.
Topics: Analgesics; Anesthesia, General; Animals; Inflammation; Injections; Injections, Intramuscular; Male; Masseter Muscle; Morphine; Mustard Plant; Naloxone; Naltrexone; Narcotic Antagonists; Nociceptors; Pain; Plant Oils; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Single-Blind Method; Somatostatin | 2008 |
Ethanol-induced social facilitation in adolescent rats: role of endogenous activity at mu opioid receptors.
Topics: Aging; Animals; Behavior, Animal; Central Nervous System Depressants; Dose-Response Relationship, Drug; Ethanol; Female; Injections, Intraperitoneal; Injections, Subcutaneous; Locomotion; Male; Models, Animal; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Social Facilitation; Somatostatin | 2009 |
A prolonged protein kinase C-mediated, opioid-related antinociceptive effect of st John's Wort in mice.
Topics: Acetic Acid; Analgesics; Analgesics, Opioid; Animals; Anthracenes; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Compounding; Hypericum; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Perylene; Phorbol Esters; Phytotherapy; Protein Kinase C; Quercetin; Somatostatin; Spectrometry, Mass, Electrospray Ionization; Statistics, Nonparametric; Time Factors | 2010 |
Evidence for a role of opioids in epoxyeicosatrienoic acid-induced cardioprotection in rat hearts.
Topics: 8,11,14-Eicosatrienoic Acid; Analgesics, Opioid; Animals; Disease Models, Animal; GTP-Binding Protein alpha Subunits, Gi-Go; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin | 2010 |
Synergistic interaction between intrathecal ginsenosides and morphine on formalin-induced nociception in rats.
Topics: Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Fixatives; Formaldehyde; Gene Expression Regulation; Ginsenosides; Injections, Spinal; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Reflex; Somatostatin | 2011 |
Endogenous opioid peptides contribute to associative LTP in the hippocampal CA3 region.
Topics: Animals; CA3 Region, Hippocampal; Long-Term Potentiation; Male; Naloxone; Narcotic Antagonists; Opioid Peptides; Perforant Pathway; Rats; Rats, Sprague-Dawley; Somatostatin | 2011 |
Distinct mechanisms underlying pronociceptive effects of opioids.
Topics: 2-Amino-5-phosphonovalerate; Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Granisetron; Hyperalgesia; Long-Term Potentiation; Male; Naloxone; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Ondansetron; Pain Threshold; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Somatostatin; Spinal Cord; Substance Withdrawal Syndrome; Synaptic Transmission | 2011 |
Erasure of a spinal memory trace of pain by a brief, high-dose opioid administration.
Topics: Analgesics, Opioid; Animals; Calcium Signaling; Evoked Potentials; Hyperalgesia; Long-Term Potentiation; Male; Naloxone; Nerve Fibers, Unmyelinated; Nociceptive Pain; Phosphorylation; Piperidines; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Opioid, mu; Remifentanil; Sciatic Nerve; Somatostatin; Spinal Cord; Synapses | 2012 |
Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the anterior pretectal nucleus.
Topics: Analgesia; Animals; Atropine; Bicuculline; Electroacupuncture; GABA-A Receptor Antagonists; Male; Mesencephalon; Methiothepin; Methysergide; Muscarinic Antagonists; Naloxone; Naltrexone; Narcotic Antagonists; Pain Management; Rats; Rats, Wistar; Serotonin Antagonists; Somatostatin | 2013 |
Central effects of ethanol interact with endogenous mu-opioid activity to control isolation-induced analgesia in maternally separated infant rats.
Topics: Animals; Central Nervous System Depressants; Drinking Behavior; Drinking Water; Ethanol; Female; Grooming; Male; Maternal Deprivation; Motor Activity; Naloxone; Narcotic Antagonists; Pain; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Saccharin; Social Isolation; Somatostatin; Stress, Psychological | 2014 |
Opioid receptor-dependent sex differences in synaptic plasticity in the hippocampal mossy fiber pathway of the adult rat.
Topics: Animals; Baclofen; Bicuculline; Dendritic Spines; Estrous Cycle; Female; GABA-A Receptor Antagonists; Hippocampus; Long-Term Potentiation; Male; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, Opioid; Sex Characteristics; Somatostatin; Synapses | 2015 |
Coactivation of μ- and κ-Opioid Receptors May Mediate the Protective Effect of Testosterone on the Development of Temporomandibular Joint Nociception in Male Rats.
Topics: Animals; Brain Stem; Facial Pain; Formaldehyde; Male; Naloxone; Naltrexone; Narcotic Antagonists; Nociception; Nociceptive Pain; Orchiectomy; Rats; Rats, Wistar; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Temporomandibular Joint; Temporomandibular Joint Disorders; Testosterone; Trigeminal Caudal Nucleus | 2016 |
μ-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Escape Reaction; Hypothalamus; Male; Naloxone; Panic; Panic Disorder; Periaqueductal Gray; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Opioid, mu; Serotonin; Somatostatin | 2017 |
Panicolytic-like effects caused by substantia nigra pars reticulata pretreatment with low doses of endomorphin-1 and high doses of CTOP or the NOP receptors antagonist JTC-801 in male Rattus norvegicus.
Topics: Aminoquinolines; Analgesics, Opioid; Animals; Benzamides; Bicuculline; Dose-Response Relationship, Drug; Fear; gamma-Aminobutyric Acid; Male; Naloxone; Nociceptin; Nociceptin Receptor; Oligopeptides; Opioid Peptides; Pars Reticulata; Rats; Rats, Wistar; Receptors, Opioid; Somatostatin; Superior Colliculi | 2017 |
NALOXONE AND CTOP BLOCK NSAIDS-INDUCED ANTINOCICEPTION IN ANTERIOR CINGULATE CORTEX OF RATS.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Gyrus Cinguli; Ketorolac; Naloxone; Narcotic Antagonists; Pain Perception; Rats; Rats, Wistar; Somatostatin | 2019 |
Dipyrone is locally hydrolyzed to 4-methylaminoantipyrine and its antihyperalgesic effect depends on CB
Topics: Analgesics; Animals; Cannabinoid Receptor Antagonists; Carrageenan; Dipyrone; Hydrolysis; Hyperalgesia; Indoles; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Opioid, kappa; Somatostatin | 2020 |
Endogenous opioid and cannabinoid systems contribute to antinociception produced by administration of NSAIDs into the insular cortex of rats.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cerebral Cortex; Endocannabinoids; Male; Naloxone; Nociception; Opioid Peptides; Piperidines; Pyrazoles; Rats; Rats, Wistar; Somatostatin | 2020 |