Compounds > phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and enkephalin, leucine

phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide has been researched along with enkephalin, leucine in 58 studies

Research

Studies (58)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (6.90)	18.7374
1990's	46 (79.31)	18.2507
2000's	6 (10.34)	29.6817
2010's	2 (3.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Herz, A; Shippenberg, TS; Spanagel, R	2
Ableitner, A; Schulz, R	1
Baumeister, AA; Hurry, MJ; Richard, AL; Richmond-Landeche, L; Waguespack, AM	1
Levine, JD; Miaskowski, C	1
Martinez, JL; Schulteis, G	1
Jacobson, AE; Ni, Q; Rice, KC; Rothman, RB; Xu, H	1
Duckles, SP; Li, YJ	1
Kromer, W	3
Lawrence, AJ; Traynor, JR	1
Gramsch, C; Hassan, AH; Herz, A; Parsons, CG; Peter, K; Przewlocki, R; Stein, C	1
Bals-Kubik, R; Herz, A; Shippenberg, TS	2
Suh, HH; Tseng, LF	1
Gulya, K; Hawkins, KN; Hruby, VJ; Kazmierski, W; Knapp, RJ; Lui, GK; Pelton, JT; Wan, YP; Yamamura, HI	1
Gulya, K; Hruby, VJ; Pelton, JT; Yamamura, HI	1
Gulya, K; Hruby, VJ; Kazmierski, W; Lui, GK; Pelton, JT; Yamamura, HI	1
Badiani, A; Leone, P; Stewart, J	1
Kradel, BK; Monroe, PJ; Smith, DJ; Smith, DL	1
Crisp, T; Keck, BJ; Stafinsky, JL; Uram, M	1
Aoki, Y; Katao, Y; Katsumata, S; Minami, M; Nakagawa, T; Onogi, T; Satoh, M	1
Garzón, J; Martínez-Peña, Y; Sánchez-Blázquez, P	1
Elliott, J; Lambert, DG; Smart, D; Traynor, JR	1
Almeida, OF; Shippenberg, TS; Spanagel, R	1
Búzás, B; Cox, BM; Izenwasser, S	1
North, RA; Tanaka, E	1
Gozariu, L; Gozariu, MS; Orbai, P; Sandor, V; Schmidt-Gayk, H	1
Carter, L; Schäfer, M; Stein, C	1
Guirimand, F; Le Bars, D; Strimbu-Gozariu, M; Willer, JC	1
Derrick, BE; Martinez, JL	2
Sheiner, LB; Troconiz, IF; Verotta, D	1
Carter, BD; Medzihradsky, F	1
North, RA; Sugita, S	1
Hyytiä, P	1
Ableitner, A; Fabian, I	1
Chieng, B; Christie, MJ; Connor, M	1
Gouardères, C; Jhamandas, K; Sutak, M; Zajac, JM	1
Davis, P; Horvath, R; Hruby, VJ; Lipkowski, AW; Misicka, A; Porreca, F; Yamamura, HI	1
Budai, D; Fields, HL	1
Foxx-Orenstein, AE; Grider, JR; Jin, JG	1
Bihm, CC; Burks, TF; Williams, CL	1
Aghajanian, GK; Marek, GJ	1
Chavkin, C; Jin, W	1
Ang, KK; Arnolda, LF; Chalmers, JP; Llewellyn-Smith, IJ; McRitchie, RJ; Minson, JB; Pilowsky, PM	1
Cooper, AJ; Stanford, IM	1
Adamson, KL; Chow, BL; Coen, KM; Corrigall, WA	1
Lohmann, AB; Welch, SP	1
Allescher, HD; Brechmann, C; Hahn, A; Schusdziarra, V; Storr, M	1
Li, P; Longhurst, JC; Tjen-A-Looi, S	1
Hung, KC; Mizoguchi, H; Nagase, H; Tseng, LF; Wu, HE	1
Brecha, NC; Kohlmeier, SE; Minnis, JG; Patierno, S; Sternini, C; Tonini, M	1
Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Oi, Y; Suzuki, T; Takada, K	1
Chavkin, C; Gendron, L; Pintar, JE	1
Balleine, BW; Cely, IC; Maidment, NT; Wassum, KM	1
Bennett, AJ; Devonshire, IM; Hathway, GJ; Kwok, CHT	1

Other Studies

58 other study(ies) available for phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and enkephalin, leucine

Article	Year
Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway. Proceedings of the National Academy of Sciences of the United States of America, 1992, Mar-15, Volume: 89, Issue:6 Topics: Analgesics; Animals; Benzeneacetamides; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Infusions, Parenteral; Limbic System; Male; Microinjections; Models, Neurological; Naltrexone; Nucleus Accumbens; Pyrrolidines; Rats; Rats, Inbred Strains; Somatostatin; Tegmentum Mesencephali	1992
Neuroanatomical sites mediating the central actions of beta-endorphin as mapped by changes in glucose utilization: involvement of mu opioid receptors. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:1 Topics: Animals; Autoradiography; Behavior, Animal; beta-Endorphin; Brain; Dose-Response Relationship, Drug; Enkephalin, Leucine; Glucose; Injections, Intraventricular; Male; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Somatostatin	1992
Further studies of the role of opioid receptors in the nigra in the morphine withdrawal syndrome. Neuropharmacology, 1992, Volume: 31, Issue:9 Topics: Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Body Temperature; Brain; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Molecular Sequence Data; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Stereotaxic Techniques; Substance Withdrawal Syndrome; Substantia Nigra	1992
Inhibition of spinal opioid analgesia by supraspinal administration of selective opioid antagonists. Brain research, 1992, Nov-20, Volume: 596, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Narcotic Antagonists; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Somatostatin	1992
Roles of delta and mu opioid receptors in mediating the effects of enkephalins on avoidance conditioning. Psychopharmacology, 1992, Volume: 109, Issue:1-2 Topics: Amino Acid Sequence; Analgesics; Animals; Avoidance Learning; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Motor Activity; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin	1992
Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes. Life sciences, 1991, Volume: 49, Issue:18 Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Molecular Sequence Data; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, delta; Somatostatin	1991
Effect of opioid receptor antagonists on vasodilator nerve actions in the perfused rat mesentery. European journal of pharmacology, 1991, Nov-12, Volume: 204, Issue:3 Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanethidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Vasodilation	1991
Voltage-clamp experiments reveal receptor type-dependent modulation of chloride secretion in the guinea pig colonic mucosa by intestinal opioids. Naunyn-Schmiedeberg's archives of pharmacology, 1991, Volume: 344, Issue:3 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alprostadil; Amiloride; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Chlorides; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gluconates; Guinea Pigs; Intestinal Mucosa; Male; Membrane Potentials; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin; Theophylline	1991
Characterisation of opioid binding sites using selective antagonists. Progress in clinical and biological research, 1990, Volume: 328 Topics: Animals; Binding, Competitive; Brain; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Indoles; Morphinans; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin	1990
Local opioid receptors mediating antinociception in inflammation: endogenous ligands. Progress in clinical and biological research, 1990, Volume: 328 Topics: Animals; Endorphins; Enkephalin, Leucine; Inflammation; Naloxone; Nociceptors; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin	1990
Involvement of central mu and delta opioid receptors in mediating the reinforcing effects of beta-endorphin in the rat. European journal of pharmacology, 1990, Jan-03, Volume: 175, Issue:1 Topics: Amino Acid Sequence; Animals; beta-Endorphin; Conditioning, Operant; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Somatostatin	1990
Reflex peristalsis in the guinea pig isolated ileum is endogenously controlled by kappa opioid receptors. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 341, Issue:5 Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Leucine; Gastrointestinal Motility; Guinea Pigs; Ileum; Male; Naloxone; Naltrexone; Narcotic Antagonists; Peristalsis; Receptors, Opioid; Receptors, Opioid, kappa; Reflex; Somatostatin	1990
Different types of opioid receptors mediating analgesia induced by morphine, DAMGO, DPDPE, DADLE and beta-endorphin in mice. Naunyn-Schmiedeberg's archives of pharmacology, 1990, Volume: 342, Issue:1 Topics: Analgesia; Animals; beta-Endorphin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Reaction Time; Receptors, Opioid; Somatostatin	1990
Identification of the opioid receptor types mediating beta-endorphin-induced alterations in dopamine release in the nucleus accumbens. European journal of pharmacology, 1990, Nov-06, Volume: 190, Issue:1-2 Topics: Analgesics; Animals; beta-Endorphin; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Somatostatin	1990
[3H]-[H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2] ([3H]CTOP), a potent and highly selective peptide for mu opioid receptors in rat brain. The Journal of pharmacology and experimental therapeutics, 1989, Volume: 248, Issue:1 Topics: Animals; Brain; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Kinetics; Magnesium; Male; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, mu; Sodium; Somatostatin; Temperature; Tritium	1989
Evidence that the aversive effects of opioid antagonists and kappa-agonists are centrally mediated. Psychopharmacology, 1989, Volume: 98, Issue:2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Brain; Conditioning, Operant; Enkephalin, Leucine; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Somatostatin	1989
Cyclic somatostatin octapeptide analogues with high affinity and selectivity toward mu opioid receptors. Life sciences, 1986, Jun-16, Volume: 38, Issue:24 Topics: Animals; Binding, Competitive; Brain; Cell Membrane; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Naloxone; Oligopeptides; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Receptors, Somatostatin; Somatostatin; Structure-Activity Relationship	1986
H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2: a potent and selective antagonist opioid receptors. NIDA research monograph, 1986, Volume: 75 Topics: Animals; Brain; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Kinetics; Naloxone; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin	1986
Intra-VTA injections of the mu-opioid antagonist CTOP enhance locomotor activity. Brain research, 1995, Aug-28, Volume: 690, Issue:1 Topics: Analysis of Variance; Animals; Drinking Behavior; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Feeding Behavior; Microinjections; Motor Activity; Rats; Receptors, Opioid, mu; Somatostatin; Ventral Tegmental Area	1995
Opioid effects on spinal [3H]5-hydroxytryptamine release are not related to their antinociceptive action. European journal of pharmacology, 1995, Jan-05, Volume: 272, Issue:1 Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Isotope Labeling; Male; Molecular Sequence Data; Naltrexone; Narcotics; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Serotonin; Somatostatin; Spinal Cord; Synaptic Transmission; Synaptosomes	1995
A lack of supersensitivity to opioid receptor agonists following chronic spinal opioid receptor antagonist administration in the rat. General pharmacology, 1995, Volume: 26, Issue:1 Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Species Specificity; Spinal Cord	1995
DAMGO, a mu-opioid receptor selective ligand, distinguishes between mu-and kappa-opioid receptors at a different region from that for the distinction between mu- and delta-opioid receptors. FEBS letters, 1995, May-01, Volume: 364, Issue:1 Topics: Amino Acid Sequence; Analgesics; Animals; Cells, Cultured; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ligands; Molecular Sequence Data; Morphine; Naloxone; Oligopeptides; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Somatostatin; Structure-Activity Relationship	1995
G-receptor antagonists increased the activating effect of mastoparan on low Km GTPase of mouse PAG. Cellular signalling, 1995, Volume: 7, Issue:2 Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Kinetics; Male; Mice; Naloxone; Peptides; Periaqueductal Gray; Receptors, Cell Surface; Somatostatin; Wasp Venoms	1995
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine. European journal of pharmacology, 1994, Aug-16, Volume: 268, Issue:3 Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured	1994
Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes. European journal of pharmacology, 1994, Oct-24, Volume: 264, Issue:2 Topics: Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Somatostatin	1994
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:1 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin	1993
Opioid actions on rat anterior cingulate cortex neurons in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:3 Pt 1 Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Glutamates; Glutamic Acid; Gyrus Cinguli; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Neurotransmitter Agents; Rats; Receptors, Opioid; Somatostatin; Synapses; Synaptic Transmission	1994
The mechanism involved in the central effect of 5-leu enkephalin on the calcitonin secretion. Romanian journal of endocrinology, 1993, Volume: 31, Issue:1-2 Topics: Animals; Calcitonin; Drug Interactions; Enkephalin, Leucine; Injections, Intraventricular; Naloxone; Narcotic Antagonists; Oxidopamine; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Sympathectomy, Chemical; Thyroid Gland	1993
Interleukin 1 beta and corticotropin-releasing factor inhibit pain by releasing opioids from immune cells in inflamed tissue. Proceedings of the National Academy of Sciences of the United States of America, 1994, May-10, Volume: 91, Issue:10 Topics: Analysis of Variance; Animals; Antibodies; beta-Endorphin; Corticotropin-Releasing Hormone; Cyclosporine; Dose-Response Relationship, Drug; Dynorphins; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Humans; Inflammation; Injections; Interleukin-1; Male; Naloxone; Pain; Rats; Rats, Wistar; Recombinant Proteins; Regression Analysis; Somatostatin	1994
Effects of mu, delta and kappa opioid antagonists on the depression of a C-fiber reflex by intrathecal morphine and DAGO in the rat. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:3 Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Spinal; Morphine; Naltrexone; Narcotic Antagonists; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Somatostatin	1994
Opioid receptor activation is one factor underlying the frequency dependence of mossy fiber LTP induction. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:7 Topics: Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin	1994
Semiparametric models for antagonistic drug interactions. Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:5 Topics: Animals; Binding, Competitive; Drug Antagonism; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Models, Biological; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin	1994
Frequency-dependent associative long-term potentiation at the hippocampal mossy fiber-CA3 synapse. Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-25, Volume: 91, Issue:22 Topics: Afferent Pathways; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Piperazines; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Somatostatin; Synapses; Synaptic Transmission; Time Factors	1994
Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain. Proceedings of the National Academy of Sciences of the United States of America, 1993, May-01, Volume: 90, Issue:9 Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Analgesics; Animals; Antibodies; Cell Membrane; Clone Cells; Corpus Striatum; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Neuroblastoma; Pertussis Toxin; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured; Virulence Factors, Bordetella	1993
Opioid actions on neurons of rat lateral amygdala in vitro. Brain research, 1993, May-28, Volume: 612, Issue:1-2 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Amino Acids; Amygdala; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; GABA-A Receptor Antagonists; In Vitro Techniques; Molecular Sequence Data; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Pyrrolidines; Rats; Somatostatin; Synapses	1993
Involvement of mu-opioid receptors in alcohol drinking by alcohol-preferring AA rats. Pharmacology, biochemistry, and behavior, 1993, Volume: 45, Issue:3 Topics: Alcohol Drinking; Amino Acid Sequence; Animals; Body Weight; Drinking Behavior; Eating; Enkephalin, Leucine; Feeding Behavior; Female; Injections, Intraventricular; Male; Molecular Sequence Data; Rats; Rats, Inbred Strains; Receptors, Opioid, delta; Receptors, Opioid, mu; Sex Characteristics; Somatostatin	1993
Mu opioid receptors modulate net chloride secretion in the guinea pig colonic mucosa in a dual fashion. Life sciences, 1993, Volume: 53, Issue:13 Topics: Alprostadil; Amiloride; Amino Acid Sequence; Animals; Chlorides; Colon; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Male; Molecular Sequence Data; Receptors, Opioid, mu; Somatostatin; Theophylline	1993
Brain sites involved in mu-opioid receptor-mediated actions: a 2-deoxyglucose study. Brain research, 1995, Oct-30, Volume: 697, Issue:1-2 Topics: Amino Acid Sequence; Animals; Autoradiography; Brain; Carbon Dioxide; Deoxyglucose; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glucose; Injections, Intraventricular; Male; Molecular Sequence Data; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin	1995
The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons. Molecular pharmacology, 1996, Volume: 50, Issue:3 Topics: Animals; Brimonidine Tartrate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Naloxone; Narcotics; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Peptides; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin	1996
Role of opioid receptors in the spinal antinociceptive effects of neuropeptide FF analogues. British journal of pharmacology, 1996, Volume: 117, Issue:3 Topics: Amino Acid Sequence; Analgesics; Analgesics, Opioid; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Injections, Spinal; Male; Molecular Sequence Data; Morphine; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Spinal Cord	1996
Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4. Life sciences, 1997, Volume: 60, Issue:15 Topics: Analgesics; Animals; Brain; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; Ileum; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Structure-Activity Relationship; Vas Deferens	1997
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons. Journal of neurophysiology, 1998, Volume: 79, Issue:2 Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail	1998
5-HT4 receptor agonists and delta-opioid receptor antagonists act synergistically to stimulate colonic propulsion. The American journal of physiology, 1998, Volume: 275, Issue:5 Topics: Animals; Benzeneacetamides; Colon; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Peptide Fragments; Peristalsis; Pyrrolidines; Receptors, Opioid, delta; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Somatostatin	1998
Central actions of endomorphins: new endogenous opioids. Proceedings of the Western Pharmacology Society, 1998, Volume: 41 Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Nociceptors; Oligopeptides; Receptors, Opioid, mu; Somatostatin; Time Factors	1998
5-Hydroxytryptamine-induced excitatory postsynaptic currents in neocortical layer V pyramidal cells: suppression by mu-opiate receptor activation. Neuroscience, 1998, Volume: 86, Issue:2 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Models, Neurological; Neocortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Receptors, Serotonin; Serotonin; Somatostatin; Synapses	1998
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation. Brain research, 1999, Mar-13, Volume: 821, Issue:2 Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission	1999
Activation of spinal opioid receptors contributes to hypotension after hemorrhage in conscious rats. The American journal of physiology, 1999, Volume: 276, Issue:5 Topics: Animals; Blood Pressure; Consciousness; Dynorphins; Endorphins; Enkephalin, Leucine; Heart Rate; Hemorrhage; Hypotension; Male; Naloxone; Narcotic Antagonists; Neural Inhibition; Rats; Rats, Inbred WKY; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Sympathetic Nervous System	1999
Presynaptic mu and delta opioid receptor modulation of GABAA IPSCs in the rat globus pallidus in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jun-15, Volume: 19, Issue:12 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; Globus Pallidus; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission; Tetrodotoxin	1999
Manipulations of mu-opioid and nicotinic cholinergic receptors in the pontine tegmental region alter cocaine self-administration in rats. Psychopharmacology, 1999, Volume: 145, Issue:4 Topics: Animals; Cocaine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Pons; Rats; Rats, Long-Evans; Receptors, Nicotinic; Receptors, Opioid, mu; Self Administration; Somatostatin; Ventral Tegmental Area	1999
ATP-gated K(+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides. European journal of pharmacology, 1999, Dec-03, Volume: 385, Issue:2-3 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adenosine Triphosphate; Analgesics; Animals; Cromakalim; Diazoxide; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Glyburide; Injections, Intraventricular; Ion Channel Gating; Male; Mice; Mice, Inbred ICR; Morphine; Naltrexone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Potassium Channels; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin	1999
Modulatory effect of endogenous and exogenous opioids on the excitatory reflex pathway of the rat ileum. Neuropeptides, 2000, Volume: 34, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Endorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Ileum; In Vitro Techniques; Male; Morphine; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Narcotics; Peristalsis; Rats; Rats, Wistar; Receptors, Opioid; Somatostatin	2000
Rostral ventrolateral medullary opioid receptor subtypes in the inhibitory effect of electroacupuncture on reflex autonomic response in cats. Autonomic neuroscience : basic & clinical, 2001, Jun-20, Volume: 89, Issue:1-2 Topics: Animals; Autonomic Nervous System; Cats; Electroacupuncture; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Gallbladder; Medulla Oblongata; Microinjections; Naltrexone; Narcotic Antagonists; Neural Inhibition; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Somatostatin	2001
Roles of endogenous opioid peptides in modulation of nocifensive response to formalin. The Journal of pharmacology and experimental therapeutics, 2002, Volume: 300, Issue:2 Topics: Animals; Antibodies, Blocking; Dynorphins; Endorphins; Enkephalins; Formaldehyde; Injections, Intraventricular; Injections, Spinal; Male; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Pain Measurement; Receptors, Opioid; Somatostatin; Spinal Cord	2002
Ligand-induced mu opioid receptor endocytosis and recycling in enteric neurons. Neuroscience, 2003, Volume: 119, Issue:1 Topics: Analgesics, Opioid; Animals; Arsenicals; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Guinea Pigs; Ileum; Immunohistochemistry; Ligands; Microscopy, Confocal; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Potassium; Receptors, Opioid, mu; Somatostatin; Sucrose; Time Factors	2003
Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens. Neuroscience, 2005, Volume: 135, Issue:1 Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin	2005
Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia. Neuroscience, 2007, Dec-19, Volume: 150, Issue:4 Topics: Animals; beta-Endorphin; Dose-Response Relationship, Drug; Dynorphins; Enkephalins; Freund's Adjuvant; Hyperalgesia; Inflammation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Measurement; Protein Precursors; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin	2007
Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food reward. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Feb-02, Volume: 31, Issue:5 Topics: Amygdala; Animals; Conditioning, Operant; Drive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Food; Guanidines; Male; Microinjections; Morphinans; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Somatostatin; Sucrose	2011
Postnatal maturation of endogenous opioid systems within the periaqueductal grey and spinal dorsal horn of the rat. Pain, 2014, Volume: 155, Issue:1 Topics: Age Factors; Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression Regulation, Developmental; Hyperalgesia; Pain Threshold; Periaqueductal Gray; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord	2014