phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide has been researched along with enkephalin, ala(2)-mephe(4)-gly(5)- in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 37 (48.68) | 18.2507 |
| 2000's | 18 (23.68) | 29.6817 |
| 2010's | 20 (26.32) | 24.3611 |
| 2020's | 1 (1.32) | 2.80 |
| Authors | Studies |
|---|---|
| Herz, A; Shippenberg, TS; Spanagel, R | 2 |
| Baumeister, AA; Hurry, MJ; Richard, AL; Richmond-Landeche, L; Waguespack, AM | 1 |
| Levine, JD; Miaskowski, C | 1 |
| Martinez, JL; Schulteis, G | 1 |
| Jacobson, AE; Ni, Q; Rice, KC; Rothman, RB; Xu, H | 1 |
| Duckles, SP; Li, YJ | 1 |
| Kromer, W | 2 |
| Lawrence, AJ; Traynor, JR | 1 |
| Bals-Kubik, R; Herz, A; Shippenberg, TS | 1 |
| Suh, HH; Tseng, LF | 1 |
| Badiani, A; Leone, P; Stewart, J | 1 |
| Kradel, BK; Monroe, PJ; Smith, DJ; Smith, DL | 1 |
| Crisp, T; Keck, BJ; Stafinsky, JL; Uram, M | 1 |
| Aoki, Y; Katao, Y; Katsumata, S; Minami, M; Nakagawa, T; Onogi, T; Satoh, M | 1 |
| Garzón, J; Martínez-Peña, Y; Sánchez-Blázquez, P | 1 |
| Elliott, J; Lambert, DG; Smart, D; Traynor, JR | 1 |
| Almeida, OF; Shippenberg, TS; Spanagel, R | 1 |
| Búzás, B; Cox, BM; Izenwasser, S | 1 |
| North, RA; Tanaka, E | 1 |
| Guirimand, F; Le Bars, D; Strimbu-Gozariu, M; Willer, JC | 1 |
| Derrick, BE; Martinez, JL | 2 |
| Sheiner, LB; Troconiz, IF; Verotta, D | 1 |
| Carter, BD; Medzihradsky, F | 1 |
| North, RA; Sugita, S | 1 |
| Ableitner, A; Fabian, I | 1 |
| Chieng, B; Christie, MJ; Connor, M | 1 |
| Budai, D; Fields, HL | 1 |
| Foxx-Orenstein, AE; Grider, JR; Jin, JG | 1 |
| Bihm, CC; Burks, TF; Williams, CL | 1 |
| Aghajanian, GK; Marek, GJ | 1 |
| Chavkin, C; Jin, W | 1 |
| Cooper, AJ; Stanford, IM | 1 |
| Adamson, KL; Chow, BL; Coen, KM; Corrigall, WA | 1 |
| Dun, NJ; Hwang, BH; Mizoguchi, H; Nagase, H; Narita, M; Oji, DE; Tseng, LF | 1 |
| Carr, JA; Lovering, AT | 1 |
| Law, PY; Loh, HH; McLeod, LA; Tine, SJ | 1 |
| Devi, LA; Gomes, I; Gupta, A; Jordan, BA; Nagy, V; Trapaidze, N | 1 |
| Clarke, PB; Fraser, GL; Pradhan, AA; Wahlestedt, C | 1 |
| Bot, G; Chesselet, MF; Mehta, A; Reisine, T | 1 |
| Micevych, PE; Sinchak, K | 1 |
| Acosta-Martinez, M; Etgen, AM | 1 |
| Bargas, J; Barral, J; Galarraga, E; Mendoza, E | 1 |
| Lunzer, MM; Portoghese, PS | 1 |
| Brecha, NC; Kohlmeier, SE; Minnis, JG; Patierno, S; Sternini, C; Tonini, M | 1 |
| Ikeda, M; Kadoi, J; Matsumoto, S; Nasu, M; Takeda, M; Tanimoto, T | 1 |
| Chen, SR; Pan, HL; Wu, ZZ | 1 |
| Liu, AM; Wong, YH | 1 |
| Cools, AR; Hirose, N; Koshikawa, N; Murakawa, K; Nagase, H; Oi, Y; Suzuki, T; Takada, K | 1 |
| Kaneko, C; Kuzumaki, N; Matsuzawa, K; Miyoshi, K; Nagumo, Y; Nakajima, M; Nanjo, K; Narita, M; Suzuki, T; Yamazaki, M | 1 |
| Bilecki, W; Przewłocki, R; Urbański, MJ; Wawrzczak-Bargieła, A; Ziółkowska, B | 1 |
| Mizoguchi, H; Nakayama, D; Sakurada, S; Sakurada, T; Watanabe, C; Watanabe, H | 1 |
| Aguilera, L; Aira, Z; Azkue, JJ; Bilbao, J; Buesa, I; Mozas, M; Salgueiro, M; Urrutia, A; Zimmermann, M | 1 |
| Azevedo, L; Barroso, PA; Castro-Lopes, JM; Neto, FL; Potes, CS; Pozza, DH | 1 |
| Fisyunov, A; Iegorova, O; Krishtal, O | 1 |
| Bajo, M; Madamba, SG; Roberto, M; Siggins, GR | 1 |
| Balleine, BW; Cely, IC; Maidment, NT; Wassum, KM | 1 |
| Gear, RW; Levine, JD | 1 |
| Kemppainen, H; Kiianmaa, K; Raivio, N; Suo-Yrjo, V | 1 |
| Al-Khrasani, M; Friedmann, T; Fürst, S; Gyarmati, S; Király, KP; Lackó, E; Lenkey, N; Riba, P; Szentirmay, AK; Timár, J; Tóth, G | 1 |
| Bonsi, P; Pisani, A; Ponterio, G; Riahi, E; Sciamanna, G; Tassone, A; Vanni, V | 1 |
| Bennett, AJ; Devonshire, IM; Hathway, GJ; Kwok, CHT | 1 |
| Aira, Z; Azkue, JJ; Barrenetxea, T; Buesa, I; Gómez-Esteban, JC | 1 |
| Audi, EA; Graeff, FG; Rangel, MP; Roncon, CM; Zangrossi, H | 1 |
| Huang, FS; Huo, FQ; Qu, CL; Tang, JS | 1 |
| Sirohi, S; Walker, BM | 1 |
| Almada, RC; Audi, EA; Coimbra, NC; Graeff, FG; Maraschin, JC; Roncon, CM; Zangrossi, H | 1 |
| Airavaara, M; Bäckström, P; Kiianmaa, K; Oinio, V; Piepponen, P; Raasmaja, A; Uhari-Väänänen, J | 1 |
| Audi, EA; Gama, VS; Graeff, FG; Maraschin, JC; Sestile, CC; Zangrossi, H | 1 |
| Audi, EA; Coimbra, NC; Frias, AT; Graeff, FG; Roncon, CM; Yamashita, PSM; Zangrossi, H | 1 |
| Alekseeva, EV; Nazarova, GA; Sudakov, SK | 1 |
| Bonsi, P; Mercuri, NB; Meringolo, M; Pisani, A; Ponterio, G; Santoro, M; Sciamanna, G; Tassone, A; Vanni, V | 1 |
| Berg, D; Berson, DM; Cleymaet, AM; Gallagher, SK; Hartwick, ATE; Lipin, MY; Renna, JM; Sodhi, P; Tooker, RE; Vigh, J | 1 |
| da Cunha, JM; Godoi, MM; Junior, HZ; Zanoveli, JM | 1 |
76 other study(ies) available for phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide and enkephalin, ala(2)-mephe(4)-gly(5)-
| Article | Year |
|---|---|
Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway.
Topics: Analgesics; Animals; Benzeneacetamides; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Infusions, Parenteral; Limbic System; Male; Microinjections; Models, Neurological; Naltrexone; Nucleus Accumbens; Pyrrolidines; Rats; Rats, Inbred Strains; Somatostatin; Tegmentum Mesencephali | 1992 |
Further studies of the role of opioid receptors in the nigra in the morphine withdrawal syndrome.
Topics: Amino Acid Sequence; Analgesics; Animals; Behavior, Animal; Body Temperature; Brain; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Molecular Sequence Data; Morphine; Morphine Dependence; Naloxone; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Stereotaxic Techniques; Substance Withdrawal Syndrome; Substantia Nigra | 1992 |
Inhibition of spinal opioid analgesia by supraspinal administration of selective opioid antagonists.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Injections, Spinal; Male; Narcotic Antagonists; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Somatostatin | 1992 |
Roles of delta and mu opioid receptors in mediating the effects of enkephalins on avoidance conditioning.
Topics: Amino Acid Sequence; Analgesics; Animals; Avoidance Learning; Electroshock; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Motor Activity; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 1992 |
Preliminary ligand binding data for subtypes of the delta opioid receptor in rat brain membranes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Brain; Cell Membrane; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine-2-Alanine; Enkephalins; Kinetics; Molecular Sequence Data; Oligopeptides; Radioligand Assay; Rats; Receptors, Opioid; Receptors, Opioid, delta; Somatostatin | 1991 |
Effect of opioid receptor antagonists on vasodilator nerve actions in the perfused rat mesentery.
Topics: Animals; Calcitonin Gene-Related Peptide; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalins; Guanethidine; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle, Smooth, Vascular; Naloxone; Naltrexone; Narcotic Antagonists; Neurons, Afferent; Perfusion; Rats; Rats, Inbred Strains; Somatostatin; Vasodilation | 1991 |
Voltage-clamp experiments reveal receptor type-dependent modulation of chloride secretion in the guinea pig colonic mucosa by intestinal opioids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Alprostadil; Amiloride; Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Chlorides; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gluconates; Guinea Pigs; Intestinal Mucosa; Male; Membrane Potentials; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pyrrolidines; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin; Theophylline | 1991 |
Characterisation of opioid binding sites using selective antagonists.
Topics: Animals; Binding, Competitive; Brain; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Indoles; Morphinans; Naltrexone; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 1990 |
Involvement of central mu and delta opioid receptors in mediating the reinforcing effects of beta-endorphin in the rat.
Topics: Amino Acid Sequence; Animals; beta-Endorphin; Conditioning, Operant; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Narcotic Antagonists; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Reinforcement, Psychology; Somatostatin | 1990 |
Different types of opioid receptors mediating analgesia induced by morphine, DAMGO, DPDPE, DADLE and beta-endorphin in mice.
Topics: Analgesia; Animals; beta-Endorphin; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Enkephalins; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; Morphine; Narcotic Antagonists; Reaction Time; Receptors, Opioid; Somatostatin | 1990 |
Identification of the opioid receptor types mediating beta-endorphin-induced alterations in dopamine release in the nucleus accumbens.
Topics: Analgesics; Animals; beta-Endorphin; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Dialysis; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Inbred Strains; Receptors, Opioid; Somatostatin | 1990 |
Intra-VTA injections of the mu-opioid antagonist CTOP enhance locomotor activity.
Topics: Analysis of Variance; Animals; Drinking Behavior; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Feeding Behavior; Microinjections; Motor Activity; Rats; Receptors, Opioid, mu; Somatostatin; Ventral Tegmental Area | 1995 |
Opioid effects on spinal [3H]5-hydroxytryptamine release are not related to their antinociceptive action.
Topics: Amino Acid Sequence; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; In Vitro Techniques; Isotope Labeling; Male; Molecular Sequence Data; Naltrexone; Narcotics; Potassium; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Serotonin; Somatostatin; Spinal Cord; Synaptic Transmission; Synaptosomes | 1995 |
A lack of supersensitivity to opioid receptor agonists following chronic spinal opioid receptor antagonist administration in the rat.
Topics: Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Male; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Species Specificity; Spinal Cord | 1995 |
DAMGO, a mu-opioid receptor selective ligand, distinguishes between mu-and kappa-opioid receptors at a different region from that for the distinction between mu- and delta-opioid receptors.
Topics: Amino Acid Sequence; Analgesics; Animals; Cells, Cultured; Endorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Ligands; Molecular Sequence Data; Morphine; Naloxone; Oligopeptides; Opioid Peptides; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Recombinant Fusion Proteins; Somatostatin; Structure-Activity Relationship | 1995 |
G-receptor antagonists increased the activating effect of mastoparan on low Km GTPase of mouse PAG.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Activation; GTP Phosphohydrolases; GTP-Binding Proteins; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Kinetics; Male; Mice; Naloxone; Peptides; Periaqueductal Gray; Receptors, Cell Surface; Somatostatin; Wasp Venoms | 1995 |
Characterisation of mu-opioid receptors on SH-SY5Y cells using naloxonazine and beta-funaltrexamine.
Topics: Amino Acid Sequence; Animals; Brain Neoplasms; Cerebral Cortex; Diprenorphine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Humans; Ligands; Molecular Sequence Data; Naloxone; Naltrexone; Neuroblastoma; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured | 1994 |
Evidence that nor-binaltorphimine can function as an antagonist at multiple opioid receptor subtypes.
Topics: Amino Acid Sequence; Analgesics; Animals; Benzeneacetamides; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Injections, Intraventricular; Male; Molecular Sequence Data; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Somatostatin | 1994 |
Differential regulation of adenylyl cyclase activity by mu and delta opioids in rat caudate putamen and nucleus accumbens.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Benzeneacetamides; Caudate Nucleus; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Male; Molecular Sequence Data; Naloxone; Naltrexone; Nucleus Accumbens; Oligopeptides; Putamen; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Somatostatin | 1993 |
Opioid actions on rat anterior cingulate cortex neurons in vitro.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Glutamates; Glutamic Acid; Gyrus Cinguli; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Neurotransmitter Agents; Rats; Receptors, Opioid; Somatostatin; Synapses; Synaptic Transmission | 1994 |
Effects of mu, delta and kappa opioid antagonists on the depression of a C-fiber reflex by intrathecal morphine and DAGO in the rat.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Spinal; Morphine; Naltrexone; Narcotic Antagonists; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reflex; Somatostatin | 1994 |
Opioid receptor activation is one factor underlying the frequency dependence of mossy fiber LTP induction.
Topics: Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin | 1994 |
Semiparametric models for antagonistic drug interactions.
Topics: Animals; Binding, Competitive; Drug Antagonism; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Injections, Intraventricular; Models, Biological; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 1994 |
Frequency-dependent associative long-term potentiation at the hippocampal mossy fiber-CA3 synapse.
Topics: Afferent Pathways; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Piperazines; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Somatostatin; Synapses; Synaptic Transmission; Time Factors | 1994 |
Go mediates the coupling of the mu opioid receptor to adenylyl cyclase in cloned neural cells and brain.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Analgesics; Animals; Antibodies; Cell Membrane; Clone Cells; Corpus Striatum; Cyclic AMP; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; GTP-Binding Proteins; Humans; Kinetics; Membrane Proteins; Neuroblastoma; Pertussis Toxin; Rats; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1993 |
Opioid actions on neurons of rat lateral amygdala in vitro.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Amino Acid Sequence; Amino Acids; Amygdala; Analgesics; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; GABA-A Receptor Antagonists; In Vitro Techniques; Molecular Sequence Data; Naloxone; Narcotic Antagonists; Narcotics; Neurons; Pyrrolidines; Rats; Somatostatin; Synapses | 1993 |
Mu opioid receptors modulate net chloride secretion in the guinea pig colonic mucosa in a dual fashion.
Topics: Alprostadil; Amiloride; Amino Acid Sequence; Animals; Chlorides; Colon; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Guinea Pigs; In Vitro Techniques; Intestinal Mucosa; Male; Molecular Sequence Data; Receptors, Opioid, mu; Somatostatin; Theophylline | 1993 |
Brain sites involved in mu-opioid receptor-mediated actions: a 2-deoxyglucose study.
Topics: Amino Acid Sequence; Animals; Autoradiography; Brain; Carbon Dioxide; Deoxyglucose; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Glucose; Injections, Intraventricular; Male; Molecular Sequence Data; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 1995 |
The mu-opioid receptor antagonist D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) [but not D-Phe-Cys-Tyr-D-Trp-Arg-Thr-Pen-Thr-NH2 (CTAP)] produces a nonopioid receptor-mediated increase in K+ conductance of rat locus ceruleus neurons.
Topics: Animals; Brimonidine Tartrate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Methionine; Enkephalins; In Vitro Techniques; Kinetics; Locus Coeruleus; Male; Naloxone; Narcotics; Neurons; Nociceptin; Opioid Peptides; Peptide Fragments; Peptides; Potassium; Potassium Channels; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 1996 |
Endogenous opioid peptides acting at mu-opioid receptors in the dorsal horn contribute to midbrain modulation of spinal nociceptive neurons.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Animals; Bicuculline; Clonidine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Excitatory Amino Acid Agonists; GABA Antagonists; Hot Temperature; Iontophoresis; Kainic Acid; Male; Medulla Oblongata; N-Methylaspartate; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Pain; Peptide Fragments; Peptides; Periaqueductal Gray; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord; Tail | 1998 |
5-HT4 receptor agonists and delta-opioid receptor antagonists act synergistically to stimulate colonic propulsion.
Topics: Animals; Benzeneacetamides; Colon; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Enkephalin, Methionine; Enkephalins; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Naltrexone; Narcotic Antagonists; Peptide Fragments; Peristalsis; Pyrrolidines; Receptors, Opioid, delta; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Receptor Agonists; Somatostatin | 1998 |
Central actions of endomorphins: new endogenous opioids.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Mice, Inbred ICR; Nociceptors; Oligopeptides; Receptors, Opioid, mu; Somatostatin; Time Factors | 1998 |
5-Hydroxytryptamine-induced excitatory postsynaptic currents in neocortical layer V pyramidal cells: suppression by mu-opiate receptor activation.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Evoked Potentials; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Models, Neurological; Neocortex; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Reaction Time; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Receptors, Serotonin; Serotonin; Somatostatin; Synapses | 1998 |
Mu opioids enhance mossy fiber synaptic transmission indirectly by reducing GABAB receptor activation.
Topics: Analgesics, Opioid; Animals; Baclofen; Bicuculline; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; GABA Antagonists; Long-Term Potentiation; Male; Membrane Potentials; Mossy Fibers, Hippocampal; Naloxone; Narcotic Antagonists; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 1999 |
Presynaptic mu and delta opioid receptor modulation of GABAA IPSCs in the rat globus pallidus in vitro.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analgesics, Opioid; Animals; Bicuculline; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Methionine; Enkephalins; Excitatory Amino Acid Antagonists; GABA Antagonists; Globus Pallidus; In Vitro Techniques; Male; Membrane Potentials; Neostriatum; Neurons; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission; Tetrodotoxin | 1999 |
Manipulations of mu-opioid and nicotinic cholinergic receptors in the pontine tegmental region alter cocaine self-administration in rats.
Topics: Animals; Cocaine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Microinjections; Pons; Rats; Rats, Long-Evans; Receptors, Nicotinic; Receptors, Opioid, mu; Self Administration; Somatostatin; Ventral Tegmental Area | 1999 |
Identification of the G-protein-coupled ORL1 receptor in the mouse spinal cord by [35S]-GTPgammaS binding and immunohistochemistry.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; Atropine; Autoradiography; Baclofen; Binding, Competitive; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Haloperidol; Immunohistochemistry; In Vitro Techniques; Male; Membranes; Mice; Mice, Inbred ICR; Naltrexone; Narcotic Antagonists; Nociceptin; Nociceptin Receptor; Opioid Peptides; Peptide Fragments; Propranolol; Receptors, Opioid; Somatostatin; Spinal Cord; Sulfur Radioisotopes; Yohimbine | 1999 |
Mu and delta opioid receptor regulation of pro-opiomelanocortin peptide secretion from the rat neurointermediate pituitary in vitro.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; alpha-MSH; Analgesics, Opioid; Animals; beta-Endorphin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; In Vitro Techniques; Male; Oligopeptides; Opioid Peptides; Pituitary Gland; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 2000 |
Association of a lower molecular weight protein to the mu-opioid receptor demonstrated by (125)I-beta-endorphin cross-linking studies.
Topics: Animals; beta-Endorphin; Cross-Linking Reagents; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Histidine; Iodine Radioisotopes; Mice; Molecular Weight; Morphine; Neuroblastoma; Proteins; Receptors, Opioid, mu; Somatostatin; Tumor Cells, Cultured | 2000 |
Heterodimerization of mu and delta opioid receptors: A role in opiate synergy.
Topics: Analgesics, Opioid; Animals; Cell Line; CHO Cells; Cricetinae; Detergents; Dimerization; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Humans; Ligands; Mice; Narcotic Antagonists; Oligopeptides; Precipitin Tests; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin | 2000 |
Supraspinal antinociceptive response to [D-Pen(2,5)]-enkephalin (DPDPE) is pharmacologically distinct from that to other delta-agonists in the rat.
Topics: Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Male; Oligonucleotides, Antisense; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Somatostatin; Spinal Cord | 2000 |
Endomorphin-1: induction of motor behavior and lack of receptor desensitization.
Topics: Animals; Behavior, Animal; Catalepsy; Cell Line; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Administration Routes; Dyskinesia, Drug-Induced; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Globus Pallidus; Humans; Male; Mice; Motor Activity; Naloxone; Narcotic Antagonists; Oligopeptides; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Transfection | 2001 |
Progesterone blockade of estrogen activation of mu-opioid receptors regulates reproductive behavior.
Topics: Analgesics, Opioid; Animals; Cell Count; Dose-Response Relationship, Drug; Drug Administration Schedule; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Estradiol; Estrogens; Female; Immunohistochemistry; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Ovariectomy; Posture; Preoptic Area; Progesterone; Rats; Rats, Long-Evans; Receptors, Opioid, mu; Sexual Behavior, Animal; Somatostatin | 2001 |
Activation of mu-opioid receptors inhibits lordosis behavior in estrogen and progesterone-primed female rats.
Topics: Analgesics, Opioid; Animals; Brain Chemistry; Diagonal Band of Broca; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Estrogens; Female; Injections, Intraventricular; Naloxone; Narcotic Antagonists; Oligopeptides; Posture; Preoptic Area; Progesterone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Sexual Behavior, Animal; Somatostatin; Ventromedial Hypothalamic Nucleus | 2002 |
The presynaptic modulation of corticostriatal afferents by mu-opioids is mediated by K+ conductances.
Topics: Afferent Pathways; Agatoxins; Analgesics, Opioid; Animals; Barium; Calcium Channels; Cerebral Cortex; Cesium; Corpus Striatum; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; In Vitro Techniques; Male; Potassium Channels; Rats; Rats, Wistar; Receptors, Opioid, mu; Somatostatin; Spider Venoms; Synaptic Transmission | 2003 |
Identity of the putative delta1-opioid receptor as a delta-kappa heteromer in the mouse spinal cord.
Topics: Animals; Benzylidene Compounds; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Immune Sera; Mice; Naltrexone; Oligopeptides; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin; Spinal Cord | 2003 |
Ligand-induced mu opioid receptor endocytosis and recycling in enteric neurons.
Topics: Analgesics, Opioid; Animals; Arsenicals; Dose-Response Relationship, Drug; Drug Interactions; Endocytosis; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Enzyme Inhibitors; Guinea Pigs; Ileum; Immunohistochemistry; Ligands; Microscopy, Confocal; Naloxone; Narcotic Antagonists; Neurons; Organ Culture Techniques; Potassium; Receptors, Opioid, mu; Somatostatin; Sucrose; Time Factors | 2003 |
Opioidergic modulation of excitability of rat trigeminal root ganglion neuron projections to the superficial layer of cervical dorsal horn.
Topics: Analgesics, Opioid; Animals; Cervical Vertebrae; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Immunohistochemistry; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Posterior Horn Cells; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rats; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Trigeminal Ganglion | 2004 |
Differential sensitivity of N- and P/Q-type Ca2+ channel currents to a mu opioid in isolectin B4-positive and -negative dorsal root ganglion neurons.
Topics: Analgesics, Opioid; Animals; Calcium Channels, N-Type; Calcium Channels, P-Type; Calcium Channels, Q-Type; Dose-Response Relationship, Drug; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ganglia, Spinal; In Vitro Techniques; Ion Channel Gating; Male; Microscopy, Confocal; Morphine; Narcotics; Patch-Clamp Techniques; Plant Lectins; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2004 |
Mu-opioid receptor-mediated phosphorylation of IkappaB kinase in human neuroblastoma SH-SY5Y cells.
Topics: Analgesics, Opioid; Analysis of Variance; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Interactions; eIF-2 Kinase; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Humans; Mitogen-Activated Protein Kinases; Naloxone; Narcotic Antagonists; Neuroblastoma; Pertussis Toxin; Phosphorylation; Receptors, Opioid, mu; Somatostatin; Time Factors | 2005 |
Interactions among mu- and delta-opioid receptors, especially putative delta1- and delta2-opioid receptors, promote dopamine release in the nucleus accumbens.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Benzylidene Compounds; Dopamine; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Extracellular Space; Male; Microdialysis; Naloxone; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin | 2005 |
Chronic pain induces anxiety with concomitant changes in opioidergic function in the amygdala.
Topics: Amygdala; Analgesics, Opioid; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Benzamides; Chronic Disease; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dynorphins; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Freund's Adjuvant; Guanosine 5'-O-(3-Thiotriphosphate); Injections, Intraventricular; Male; Maze Learning; Mice; Mice, Inbred C57BL; Naltrexone; Narcotic Antagonists; Narcotics; Pain; Pain Measurement; Piperazines; Protein Binding; Pyrrolidines; Rats; Rats, Sprague-Dawley; Reaction Time; Sciatica; Somatostatin; Sulfur Isotopes; Time Factors; Tranquilizing Agents | 2006 |
Morphine activates Arc expression in the mouse striatum and in mouse neuroblastoma Neuro2A MOR1A cells expressing mu-opioid receptors.
Topics: AIDS-Related Complex; Analysis of Variance; Animals; Blotting, Western; Cell Line, Tumor; Corpus Striatum; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enzyme Inhibitors; Flavonoids; Gene Expression; Gene Expression Regulation; Indoles; Male; Maleimides; Mice; Mice, Inbred C57BL; Morphine; Narcotics; Neuroblastoma; Receptors, Opioid, mu; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Somatostatin; Time Factors | 2005 |
A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes of mu-opioid receptors.
Topics: Analgesics, Opioid; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Hot Temperature; Injections, Intraventricular; Male; Mice; MSH Release-Inhibiting Hormone; Naloxone; Narcotic Antagonists; Oligopeptides; Pain; Pain Measurement; Pain Threshold; Reaction Time; Receptors, Opioid, mu; Somatostatin; Time Factors | 2007 |
Depression of C fibre-evoked spinal field potentials by the spinal delta opioid receptor is enhanced in the spinal nerve ligation model of neuropathic pain: involvement of the mu-subtype.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Evoked Potentials; Male; Narcotic Antagonists; Nerve Fibers, Unmyelinated; Neuralgia; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord | 2008 |
Nociceptive behaviour upon modulation of mu-opioid receptors in the ventrobasal complex of the thalamus of rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Ankle; Behavior, Animal; Disease Models, Animal; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Inflammation; Male; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Rats; Rats, Wistar; Reaction Time; Receptors, Opioid, mu; Somatostatin; Time Factors; Ventral Thalamic Nuclei | 2010 |
G-protein-independent modulation of P-type calcium channels by mu-opioids in Purkinje neurons of rat.
Topics: Animals; Calcium Channels, P-Type; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Oligopeptides; Protein Kinase C; Purkinje Cells; Rats; Receptors, Opioid, mu; Somatostatin; Thionucleotides | 2010 |
Neuroadaptation of GABAergic transmission in the central amygdala during chronic morphine treatment.
Topics: Amygdala; Analgesics, Opioid; Animals; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Inhibitory Postsynaptic Potentials; Male; Miniature Postsynaptic Potentials; Morphine; Narcotics; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Opioid, mu; Somatostatin; Synaptic Transmission | 2011 |
Micro-opioid receptor activation in the basolateral amygdala mediates the learning of increases but not decreases in the incentive value of a food reward.
Topics: Amygdala; Animals; Conditioning, Operant; Drive; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine; Food; Guanidines; Male; Microinjections; Morphinans; Naltrexone; Narcotic Antagonists; Neuropsychological Tests; Rats; Rats, Long-Evans; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Somatostatin; Sucrose | 2011 |
Nucleus accumbens facilitates nociception.
Topics: Analysis of Variance; Animals; Electrodes, Implanted; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Injections, Spinal; Lidocaine; Male; Naltrexone; Narcotic Antagonists; Nucleus Accumbens; Pain; Pain Measurement; Pain Perception; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Somatostatin; Spinal Cord | 2011 |
Opioidergic modulation of ethanol self-administration in the ventral pallidum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol Drinking; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Globus Pallidus; Male; Microinjections; Morphine; Motor Activity; Naltrexone; Narcotic Antagonists; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Self Administration; Somatostatin | 2012 |
Spinal interaction between the highly selective μ agonist DAMGO and several δ opioid receptor ligands in naive and morphine-tolerant mice.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ligands; Male; Mice; Morphine; Pain Measurement; Receptors, Opioid, delta; Somatostatin; Spinal Cord; Vas Deferens | 2013 |
Powerful inhibitory action of mu opioid receptors (MOR) on cholinergic interneuron excitability in the dorsal striatum.
Topics: Action Potentials; Analgesics, Opioid; Anesthetics, Local; Animals; Cadmium Chloride; Cholinergic Neurons; Corpus Striatum; Dopamine Agonists; Dose-Response Relationship, Drug; Drug Interactions; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agents; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Neural Inhibition; Quinpirole; Receptors, Opioid, mu; Somatostatin; Tetrodotoxin | 2013 |
Postnatal maturation of endogenous opioid systems within the periaqueductal grey and spinal dorsal horn of the rat.
Topics: Age Factors; Analgesics, Opioid; Analysis of Variance; Animals; Animals, Newborn; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Gene Expression Regulation, Developmental; Hyperalgesia; Pain Threshold; Periaqueductal Gray; Pro-Opiomelanocortin; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin; Spinal Cord | 2014 |
Synaptic upregulation and superadditive interaction of dopamine D2- and μ-opioid receptors after peripheral nerve injury.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Disks Large Homolog 4 Protein; Dopamine Agonists; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Evoked Potentials; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Nerve Fibers, Unmyelinated; Peripheral Nerve Injuries; Quinpirole; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Receptors, Opioid, mu; Somatostatin; Synapses; Synaptophysin; Up-Regulation | 2014 |
Interaction between μ-opioid and 5-HT1A receptors in the regulation of panic-related defensive responses in the rat dorsal periaqueductal grey.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Electric Stimulation; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Escape Reaction; Male; Microinjections; Panic; Periaqueductal Gray; Rats; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptors, Opioid, mu; Somatostatin | 2014 |
Activation of mu-opioid receptors in the ventrolateral orbital cortex inhibits the GABAergic miniature inhibitory postsynaptic currents in rats.
Topics: Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; gamma-Aminobutyric Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Miniature Postsynaptic Potentials; Neurons; Patch-Clamp Techniques; Prefrontal Cortex; Rats, Sprague-Dawley; Receptors, Opioid, mu; Somatostatin | 2015 |
Maturational alterations in constitutive activity of medial prefrontal cortex kappa-opioid receptors in Wistar rats.
Topics: Age Factors; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guanosine 5'-O-(3-Thiotriphosphate); Male; Naltrexone; Narcotic Antagonists; Prefrontal Cortex; Protein Binding; Radionuclide Imaging; Rats; Rats, Wistar; Receptors, Opioid, kappa; Somatostatin; Sulfur Isotopes | 2015 |
Pharmacological evidence for the mediation of the panicolytic effect of fluoxetine by dorsal periaqueductal gray matter μ-opioid receptors.
Topics: Analgesics, Opioid; Animals; Avoidance Learning; Catheters, Indwelling; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Escape Reaction; Fluoxetine; Male; Microinjections; Narcotic Antagonists; Neuropsychological Tests; Periaqueductal Gray; Psychotropic Drugs; Random Allocation; Rats, Wistar; Receptors, Opioid, mu; Somatostatin | 2015 |
Accumbal μ-Opioid Receptors Modulate Ethanol Intake in Alcohol-Preferring Alko Alcohol Rats.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Ethanol; Male; Microinjections; Morphine; Nucleus Accumbens; Rats; Receptors, Opioid, kappa; Receptors, Opioid, mu; Reward; Somatostatin; Species Specificity | 2016 |
Panicolytic-like action of bradykinin in the dorsal periaqueductal gray through μ-opioid and B2-kinin receptors.
Topics: Analgesics, Opioid; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Anxiety Agents; Bradykinin; Bradykinin B2 Receptor Antagonists; Captopril; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Escape Reaction; Male; Panic; Periaqueductal Gray; Rats, Wistar; Receptor, Bradykinin B2; Receptors, Opioid, mu; Somatostatin | 2017 |
μ-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Escape Reaction; Hypothalamus; Male; Naloxone; Panic; Panic Disorder; Periaqueductal Gray; Piperazines; Pyridines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Opioid, mu; Serotonin; Somatostatin | 2017 |
Effect of Peripheral μ-, δ-, and κ-Opioid Ligands on the Development of Tolerance to Ethanol-Induced Analgesia.
Topics: Analgesia; Analgesics, Opioid; Animals; Blood-Brain Barrier; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, Leucine-2-Alanine; Estradiol; Ethanol; Fulvestrant; Male; Narcotic Antagonists; Pain Management; Pain Measurement; Quetiapine Fumarate; Rats; Rats, Wistar; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Somatostatin | 2017 |
Enhanced mu opioid receptor-dependent opioidergic modulation of striatal cholinergic transmission in DYT1 dystonia.
Topics: Acetylcholine; Action Potentials; Adenosine Triphosphate; Analgesics, Opioid; Animals; Calcium; Choline O-Acetyltransferase; Cholinergic Neurons; Corpus Striatum; Disease Models, Animal; Dystonia; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Gene Expression Regulation; Male; Mice; Mice, Transgenic; Molecular Chaperones; Patch-Clamp Techniques; Receptors, Opioid, mu; Somatostatin | 2018 |
μ-Opioid Receptor Activation Directly Modulates Intrinsically Photosensitive Retinal Ganglion Cells.
Topics: Analgesics, Opioid; Animals; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Narcotic Antagonists; Peptides; Rats; Receptors, Opioid, mu; Retinal Ganglion Cells; Somatostatin | 2019 |
Mu-opioid and CB1 cannabinoid receptors of the dorsal periaqueductal gray interplay in the regulation of fear response, but not antinociception.
Topics: Analgesics, Opioid; Animals; Arachidonic Acids; Behavior, Animal; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Agonists; Fear; Freezing Reaction, Cataleptic; Male; Microinjections; N-Methylaspartate; Nociception; Pain; Pain Measurement; Periaqueductal Gray; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB1; Receptors, Opioid, mu; Somatostatin | 2020 |