phenylalanine has been researched along with tyrosine in 4184 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2238 (53.49) | 18.7374 |
| 1990's | 587 (14.03) | 18.2507 |
| 2000's | 729 (17.42) | 29.6817 |
| 2010's | 471 (11.26) | 24.3611 |
| 2020's | 159 (3.80) | 2.80 |
| Authors | Studies |
|---|---|
| Akamatsu, M; Asao, M; Fujita, T; Iwamura, H | 1 |
| Bundgaard, H; Nielsen, NM | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H | 1 |
| Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H | 1 |
| Abdalla, A; Friesema, EC; Ganguly, S; Halestrap, AP; Manning Fox, JE; Visser, TJ | 1 |
| Innocenti, A; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Innocenti, A; Nishimori, I; Onishi, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Innocenti, A; Kaila, K; Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Nishimori, I; Pastorek, J; Pastorekova, S; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Nishimori, I; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Ferry, JG; Innocenti, A; Scozzafava, A; Supuran, CT; Zimmerman, SA | 1 |
| Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M | 1 |
| Arslan, O; Aydin, M; Guler, OO; Innocenti, A; Isik, S; Kockar, F; Scozzafava, A; Supuran, CT | 1 |
| Hilvo, M; Innocenti, A; Parkkila, S; Scozzafava, A; Supuran, CT | 1 |
| Hall, RA; Innocenti, A; Mühlschlegel, FA; Scozzafava, A; Supuran, CT | 1 |
| Innocenti, A; Leewattanapasuk, W; Manole, G; Mühlschlegel, FA; Scozzafava, A; Supuran, CT | 1 |
| Bertucci, A; Supuran, CT; Tambutté, S; Vullo, D; Zoccola, D | 1 |
| Capasso, C; Carginale, V; De Luca, V; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Akdemir, A; Capasso, C; Carginale, V; De Luca, V; Rossi, M; Scozzafava, A; Supuran, CT; Vullo, D | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Capasso, C; Del Prete, S; Supuran, CT; Vullo, D | 1 |
| Augustyn, E; Chien, HC; Colas, C; Finke, K; Giacomini, KM; Hansen, L; Heeren, N; Lin, L; Schlessinger, A; Thomas, AA; Zur, AA | 1 |
| Augustyn, E; Chien, HC; Colas, C; Finke, K; Flint, A; Giacomini, KM; Hansen, L; Heeren, N; Hernandez, C; Lin, L; Miller, S; Schlessinger, A; Thomas, AA; Zur, AA | 1 |
| AlOthman, Z; Capasso, C; Del Prete, S; Donald, WA; Osman, SM; Supuran, CT; Vullo, D | 1 |
| Anthony, A; Augustyn, E; Bauer, J; Campbell, J; Chien, HC; Colas, C; Finke, K; Flint, A; Fotiadis, D; Giacomini, KM; Hall, C; Hansen, L; Heeren, N; Hernandez, C; Schlessinger, A; Springer, S; Stoner, L; Thomas, AA; Venteicher, B; Zur, AA | 1 |
| DeLeo, AB; Sprinson, DB | 1 |
| Herrmann, KM; McCray, JW | 1 |
| Hadar, R; Kuhn, J; Slonim, A | 1 |
| Montoya, AL; Nester, EW | 1 |
| Friedrich, B; Friedrich, CG; Schlegel, HG | 2 |
| Harmar, AJ; Horn, AS | 1 |
| Shiio, I; Sugimoto, S | 5 |
| Kaufman, S | 11 |
| DeMarco, A; Wagner, G; Wüthrich, K | 1 |
| Lingens, F | 2 |
| Gollub, EG; Hu, RC; Liu, KP; Sprinson, DB | 1 |
| Katz, I; Kaufman, S; Lloyd, T | 1 |
| Axelrod, J; Saavedra, JM; Tallman, JF | 1 |
| Kolattukudy, PE; Lin, TS | 2 |
| Anteunis, MJ; Lala, AK; Lala, K | 1 |
| Turner, RB | 1 |
| Daniel, PM; Moorhouse, SR; Pratt, OE | 2 |
| Fernstrom, JD | 1 |
| Gelfand, DH; Steinberg, RA | 1 |
| Bouletreau, P; Delafosse, B; Motin, J | 1 |
| Kapatos, G; Zigmond, M | 1 |
| Baurain, R; Guay, M; Lamy, F; Larochelle, JF | 1 |
| Balaram, P; Das, MK; Vithayathil, PJ | 1 |
| Tanaka, Y; Uritani, I | 1 |
| Martín, JF | 1 |
| Bothner-By, AA; Hartshorne, DJ; Seamon, KB | 1 |
| Brandts, JF; Brennan, M | 1 |
| Toulme, JJ | 1 |
| Cabassi, F; Guarneri, M; Tomatis, R; Zetta, L | 1 |
| Beintema, JJ; Bolscher, BG; Kaptein, R; Lenstra, JA | 1 |
| Fernstrom, JD; Munro, HN; Wurtman, RJ | 1 |
| Clayton, BE; Smith, I; Wolff, OH | 1 |
| Hoffbauer, RW; Mönch, E; Schrempf, G | 1 |
| Berman, JL; Ford, RC | 1 |
| Held, KR; Koepp, P | 1 |
| Rizzuto, F; Spikes, JD | 1 |
| Dukes, DC; Knell, AJ | 1 |
| De Potter, WP; De Schaepdryver, AF; Fraeyman, NH | 1 |
| Aarstad, K; Laland, SG; Zimmer, TL | 1 |
| Fischer, JE; James, JH; Jeppsson, B; Ziparo, V | 1 |
| Abell, CW; Adams, PM; Barratt, ES; Fritz, PR; Poffenbarger, PL | 1 |
| Munro, HM | 1 |
| Baine, WB; Rasheed, JK | 1 |
| Ferenci, P; Funovics, J; Wewalka, F | 1 |
| Barber, R; Dodd, G; Primrose, S | 1 |
| Chandy, S; Joshua, GE; Mammen, D; Mathai, KV; Radhakrishnan, AN | 1 |
| Gupta, VJ; Wilcken, DE | 1 |
| Striebel, JP; Weitzel, H; Zenz, M | 1 |
| Berry, HK; Butcher, RE; Kazmaier, KJ; Poncet, IB | 1 |
| Chapman, LF; Phares, W | 1 |
| Eroğlu, L; Güngör, M; Koyuncuoğlu, H | 1 |
| Sakurada, S | 1 |
| Delvalle, JA; Greengard, O | 1 |
| Curzon, G; Fernando, JC; Knott, PJ | 1 |
| Antonas, KN; Coulson, WF | 1 |
| Frey, GH | 1 |
| Curzon, G; Fernando, JC | 1 |
| Gimenez, C; Maties, M; Mayor, F; Ugarte, M; Valdivieso, F | 1 |
| Jensen, RA; Patel, N; Pierson, DL; Saint Pierre, M; Zamir, L | 1 |
| Biserte, G; Dautrevaux, M; Dhondt, JL; Farriaux, JP | 1 |
| Delvalle, JA; Dienel, G; Greengard, O | 1 |
| Akeson, AL; Berry, HK; Brunner, RL; Vorhees, CV | 1 |
| Lee, SG; Lipmann, F | 1 |
| Maki, AH; Zuclich, JA | 1 |
| Goldsmith, LA | 1 |
| Allerhand, A; Norton, RS; Oldfield, E | 1 |
| Hasselmann, C; Laustriat, G | 1 |
| Biggio, G; Gessa, GL; Porceddu, ML | 1 |
| Bienfang, DC; Kuwabara, T; Pueschel, SM | 1 |
| Lohmann, W; Neubacher, H; Sportelli, L | 1 |
| Shaposhnikov, AM; Skachkov, MM; Solov'ev, VN | 1 |
| Arfmann, HA; Seipke, G; Wagner, KG; Wehling, K | 1 |
| Dev, B; Mishra, GC | 1 |
| Choo, KH; Cotton, RG | 1 |
| Azhipa, IaI; Kaiushin, LP; Reutov, VP | 1 |
| Doeden, D; Fisch, RO; Koep, LJ; Kohlhoff, JG; McCabe, ER; Silverman, A; Starzl, TE | 1 |
| Armitage, IM; Coleman, JE | 1 |
| Gibbons, WA; Kuo, M | 1 |
| Ely, B; Pittard, J | 1 |
| Borazan, HN; Durand, M; Hélène, C; Maurizot, JC | 1 |
| Wagner, G; Wüthrich, K | 1 |
| Dobson, CM; Moore, GR; Williams, RJ | 1 |
| Drapeau, GR; Dugas, H; Finkenstadt, WR; Leduc, P; Markley, JL | 1 |
| Fyrö, B; Nybäck, H; Sedvall, G; Wiesel, FA | 1 |
| Barker, RW; Brown, FF; Drake, R; Halsey, MJ; Richards, RE | 1 |
| Montie, TC; Smith, PB | 1 |
| Friedrich, CG; Schlegel, HG | 1 |
| Gattner, HG | 1 |
| Lähdesmäki, P; Oja, SS; Vanhatalo, A | 1 |
| Jensen, OA | 1 |
| Watson, PG | 1 |
| Bessman, SP; Koch, R; Williamson, ML | 1 |
| Kiely, ME; Sourkes, TL | 1 |
| Pratt, OE | 1 |
| Kaufmann, R; Mohan, R; Steiner, R | 1 |
| Wirz-Justice, A | 1 |
| Carlsson, A; Lindqvist, M | 2 |
| Yoshii, T | 1 |
| Chalmers, RA; Purkiss, P; Watts, RW | 1 |
| Matthews, HR; Matthews, KS; Opella, SJ | 1 |
| Cramer, F; Hobbs, JB; Kucharzewski, M; Sprinzl, M | 1 |
| Krauss, G; Maass, G; Peters, F; Pingoud, A; Urbanke, C | 1 |
| Pittard, AJ; Whipp, MJ | 1 |
| Bohman, K; Isaksson, LA | 1 |
| Umbarger, HE | 3 |
| Jones, MR; Kopple, JD; Swendseid, ME | 1 |
| Biraghi, A; Carbone, ML; de Scrilli, A; Lucchini, G; Magni, GE | 1 |
| Pratt, ML; Shive, W; Yoo, SH | 1 |
| Bounous, G; Kongshavn, PA | 1 |
| Brown, KD; Zurawski, G | 3 |
| Bessman, SP | 2 |
| Arnold, HH; Ogilvie, A | 1 |
| Jensen, RA; Patel, N; Pierson, DL | 1 |
| Graham, DG; Tiffany, SM; Vogel, FS | 1 |
| Gebre-Medhin, M; Larsson, U; Lindblad, BS; Zetterström, R | 1 |
| Fisher, JE; Hodgman, J; James, JH; Rosen, HM; Soeters, PB | 1 |
| Jensen, RA; Patel, N; Stenmark-Cox, SL | 1 |
| de Souza, SW; Pickard, FJ; Tricklebank, MD | 1 |
| Strauss, PR | 1 |
| Breslow, E; Sax, M; Wang, BC; Yoo, CS | 1 |
| Nishizawa, R; Takeuchi, H; Tamura, H | 1 |
| Castorina-Ziparo, S; Edelstein, E; Fischer, JE; James, JH; Ziparo, V | 1 |
| Dobson, CM; Woodworth, RC | 1 |
| Harter, HR; Karl, IE; Kipnis, DM; Klahr, S | 1 |
| Abell, CW; Fritz, RR; Shen, RS | 1 |
| Lundholm, K; Scherstén, T | 1 |
| Kohsaka, M; Okita, M; Shohmori, T | 1 |
| Königshofer, H; Lubec, G; Thalhammer, O | 1 |
| Birnbaum, D; Bode, R | 2 |
| Abell, CW; Gershon, ES; Shen, RS; Targum, SD | 1 |
| Hirayama, C; Yoshida, K | 1 |
| Bessman, SP; Crawford, R; Fujimoto, A | 1 |
| Kägi, JH; Mertens, ML; Nagayama, K; Vasák, M; Wüthrich, K | 1 |
| Fritz, RR; Johnson, KM; Vickroy, TW | 1 |
| Kaletha, K | 1 |
| Biondi, A; Biondi, G; Gallone, U; Padula, P; Pignero, A; Quagliuolo, L | 1 |
| Brandt, IK; Elsas, LJ; Jackson, CE; Nance, CS; Nance, WE; Paul, TD | 1 |
| Cividini, D; Daroda, C; Giovannini, M; Riva, E; Stival, G | 1 |
| Bickel, H | 1 |
| Farishian, RA; Whittaker, JR | 2 |
| Lifehitz, F; Moak, SA; Wapnir, RA | 1 |
| Zammarchi, E | 1 |
| Brown, JW; Conkin, AL; Lasley, SM; Thurmond, JB | 1 |
| Berry, HK; Butcher, RE; Kazmaier-Novak, KJ; Kindt, CW; Vorhees, CV | 1 |
| Barthon, F; Charpentier, C; Domange, C; Laggoune, B; Lemonnier, A; Wolf, M | 1 |
| Davidson, CS; Fernstrom, JD; Hammarstrom-Wiklund, B; Munro, HN; Rand, WM; Wurtman, RJ | 2 |
| Borkowska, I | 1 |
| Borisy, GG; Rodriguez, JA | 1 |
| Biadaioli, R; Bougleux, T; De Nigris, L; Liberati, G; Maffei, C; Zammarchi, E | 1 |
| Hannus, ML; Lähdesmäki, P | 1 |
| Güttler, F; Hansen, G | 3 |
| Holub, J; Hoza, J; Hyánek, J; Karger, P; Kunová, V; Simková, M; Stechovská, M; Valík, A | 1 |
| Kokolis, N; Stichler, W; Ziegler, I | 1 |
| Kokolis, N; Ziegler, I | 1 |
| De Montis, MG; Haber, B; Olianas, MC; Tagliamonte, A | 1 |
| Fell, V; Hoskins, JA; Pollitt, RJ | 1 |
| Herndon, DN; Mason, AD; Pruitt, BA; Wilmore, DW | 1 |
| Baerlocher, K; Curtius, HC; Leimbacher, W; Redweik, U; Schaub, J; Zagalak, MJ | 1 |
| Demain, AL; Sanchez, S | 1 |
| Francis, MM; Jones, A; Vining, LC | 1 |
| Woody, NC | 1 |
| Arce, CA; Barra, HS; Caputto, R; Hallak, ME; Rodriguez, JA | 2 |
| Brandt, IK; Elsas, LJ; Jackson, CE; Mamunes, P; Nance, CS; Nance, WE; Paul, TD | 1 |
| Bechelli, LM; Gonçalves, RP; Pagnano, PM; Tanaka, AM | 1 |
| Ahmed, SI; Syrotuck, JA; Worthington, BS | 1 |
| Dunkel, R; Luckner, M; Müller, W | 1 |
| Matolon, R; Michals, K; Wong, PW | 1 |
| Balestrieri, C; Colonna, G; Giovane, A; Irace, G; Servillo, L | 2 |
| Chase, RA; Davies, M; Silk, DB; Trewby, PN; Williams, R | 1 |
| Tobe, SS | 1 |
| Milsom, JP; Morgan, MY; Sherlock, S | 1 |
| Christen, P; Mavrides, C | 1 |
| Kitagawa, T; Owada, M | 1 |
| Enzenauer, J; Matz, D; Menne, F | 1 |
| Gamble, RC; Schoemaker, HJ | 1 |
| Murray, GE; Smith-Keary, PF | 1 |
| White, PJ | 1 |
| Daniel, J | 1 |
| Haber, M; Koch, R; Shaw, KN; Williamson, M | 1 |
| Davis, AL; Gage, LD; Grimes, JF; Hulme, KL; McCord, TJ; Robinson, LQ; Smith, DR; Winters, DW | 1 |
| Jensen, RA; Stenmark-Cox, S | 1 |
| D'Ambrosio, SM; Glover, GI; Jensen, RA | 2 |
| Aguirre, A; Fischer, JE; Funovics, JM; James, JH; Keane, JM; Wesdorp, RI; Westman, T; Yoshimura, N | 1 |
| Kenyon, RH; Moe, JB; Powanda, MC | 1 |
| Kremer, IuN; Pupele, OIa; Shmidt, AA; Vitolinia, SP | 1 |
| Arnold, HH; Kersten, H; Mahal, G; Raettig, R; Schmidt, W | 1 |
| Bozcuk, AN | 1 |
| Beisel, WR; Dinterman, RE; Klainer, AS; Wannemacher, RW | 1 |
| Abell, CW; Adams, PM; Barratt, ES; Fritz, RR; Poffenbarger, PL | 1 |
| Charpentier, C; Saudubray, JM | 1 |
| Ferguson, AG; Lesch, M; Taegtmeyer, H | 1 |
| Archer, EG; Breakefield, XO; Sharata, MN | 1 |
| Cohn, RM; Segal, S; Yost, B; Yudkoff, M | 1 |
| Anda, LP; Bantzer, P; Liappis, N | 1 |
| Hruby, VJ; Linn, DK; Upson, DA; Yamamoto, DM | 1 |
| Gaull, GE; Heinonen, K; Räihä, NC; Rassin, DK | 1 |
| Luisi, PL; Saltman, R; Vlach, D | 1 |
| Epstein, P; Stone, AL | 1 |
| Nordal, A; Paulsen, BS; Wold, JK | 1 |
| Bagchi, SP; Smith, TM | 3 |
| Mydlil, V; Tomásová, H; Tresohlavá, Z | 1 |
| Abdel Aziz, FT; Almallah, Z; Alsayed, M; Alshamaony, L; Shikara, I | 1 |
| Güttler, F; Wamberg, E | 2 |
| Anwar, RA | 1 |
| Mönch, E; Stäblein, W; Winkelmann, M | 1 |
| Abell, CW; Shen, RS | 1 |
| Costa, E; Galli, CL; Neff, NH | 1 |
| Jagenburg, R; Olsson, R; Regårdh, CG; Rodjer, S | 1 |
| Baker, DH; Robbins, KR | 1 |
| Daday, A; Roberts, DV; Smith, GD | 1 |
| Armstrong, DW; Fendler, JH | 1 |
| Gambardella, RL; Richardson, KE | 1 |
| Jagenburg, R; Regårdh, CG; Rödjer, S | 1 |
| Ichikawa, T; Terada, H | 1 |
| Berg, A; Keul, J | 1 |
| Curtius, HC; Leimbacher, W; Redweik, U; Zagalak, MJ | 1 |
| Bjarnason-Baumann, B; Pfaender, P; Siebert, G | 1 |
| Anderson, GH; Ashley, DV | 1 |
| Ersser, RS | 1 |
| Murrin, LC; Roth, RH | 1 |
| Davis, SR; Mepham, TB | 1 |
| Dautrevaux, M; Dumur, V | 1 |
| Berry, HK | 1 |
| Choo, KH; Cotton, RG; Danks, DM | 1 |
| Cummings, MG; Fischer, JE; James, JH; Kean, JM; Soeters, PB | 1 |
| Bruckheimer, S; Burkert, LB; Pisciotta, AV; Ranney, HM; Sharma, VS | 1 |
| Goldfeder, A; Mukerjee, H | 1 |
| Andersen, AE; Avins, L | 1 |
| Burgen, AS; Feeney, J; Griffiths, DV; Roberts, GC | 1 |
| Kay, CM; McCubbin, WD | 1 |
| Barbeau, A; Beroniade, V; Breton, G; Geoffroy, G; Lemieux, B; Melançon, S; Shapcott, D | 1 |
| Blaskovics, ME; Byrd, DJ; Kochen, W; Lutz, P; Trefz, FK | 1 |
| Grahame-Smith, DG; Green, AR; Woods, HF; Youdim, MB | 1 |
| Blair, JA; Green, A; Leeming, RJ; Raine, DN | 1 |
| Bleicher, SJ; Flores, A; Gombos, G; Recitas, D; Shu, J; Stern, SB | 1 |
| Koch, R; Schaeffler, G; Shaw, NF | 1 |
| Zannoni, VG | 1 |
| Woolf, LI | 2 |
| Lowe, NR; Robinson, C; Weatherell, JA | 1 |
| Gelin, BR; Karplus, M | 1 |
| Faller, DV; Fernstrom, JD; Shabshelowitz, H | 1 |
| McKean, CM; Schafer, EW | 1 |
| Deisenhofer, J; Hetzel, R; Huber, R; Wüthrich, K | 1 |
| Yamamoto, O | 1 |
| Boehme, D; Krauss, G; Maas, G; Peters, F; Pingoud, A; Riesner, D | 1 |
| Danho, WO; Gattner, HG; Nissen, D; Zahn, H | 1 |
| Corwin, LM; Thorne, GM | 1 |
| Okuda, A; Yamamoto, O | 1 |
| Hoffman, B; Koepp, P | 1 |
| Packer, EL; Sternlicht, H | 1 |
| Floss, HG; Larsen, PO; Onderka, DK | 1 |
| Dardenne, GA; Larsen, PO; Wieczorkowska, E | 1 |
| Brown, ES; Kitagawa, T; Smith, BA | 1 |
| Macdonald, JC; Slater, GP | 1 |
| Elsas, LJ; Griffin, RF | 1 |
| Heathcote, JG; Keogh, BJ; Washington, RJ | 1 |
| Angsusingha, K; Punnakanta, L; Tuchinda, C | 1 |
| Bayer, E; Hemmasi, B | 1 |
| Chellemi, F | 1 |
| Oja, SS; Vahvelainen, ML | 2 |
| Behal, FJ; Garner, CW | 1 |
| Furie, B; Griffin, JH; Schechter, AN | 1 |
| Hutsell, TC; Mares, SE; Raczialowski, FM; Ranney, RE; Schroeder, RE | 1 |
| Friedrich, B; Schlegel, HG | 2 |
| Dickens, G; Guroff, G; Letendre, CH | 1 |
| Brambilla, F; Giardini, M; Russo, R | 1 |
| Kirby, GW; Narayanaswami, S; Rao, PS | 1 |
| Maier, WA; Nassif-Makki, H | 1 |
| Eisenbach, GM; Stolte, H; Weise, M | 1 |
| De Bree, PK; Grimberg, MT; Ketting, D; Kruijswijk, H; Van der Heiden, C; Wadman, SK | 1 |
| Lähdesmäki, P; Oja, SS | 1 |
| Frenkel, MJ; Gillespie, JM; Reis, PJ | 1 |
| Hull, WE; Sykes, BD | 1 |
| Chalmers, RA; Lawson, AM; Liberman, MM; Watts, RW | 1 |
| Bartholomé, K; Bickel, H; Lutz, P | 1 |
| Barbi, S; Bondoli, A; Magalini, SI; Pelosi, G; Rocchi, C; Scrascia, E | 1 |
| Karoum, F; Ruthven, CR; Sandler, M | 1 |
| Arce, CA; Barra, HS; Caputo, R; Rodriguez, JA | 1 |
| Iijima, S; Ishii, A; Miyakoshi, T; Musha, M; Odaira, T | 1 |
| Bulakhova, LA | 1 |
| Erfle, JD; Mahadevan, S; Sauer, FD | 1 |
| Guadalix, FJ; Ruiz, MC | 1 |
| Raine, DN; Westwood, A | 1 |
| Reis, PJ | 1 |
| Berjonneau, AM; Calvot, C; Gellf, G; Thomas, D | 1 |
| Lanza, I | 1 |
| Biguet, J; Dujardin, L; Lacoste, L | 1 |
| Kisara, K; Sakurada, S; Shoji, T | 1 |
| Ache, HJ; Wong, S | 1 |
| Anderson, VE; Siegel, FS | 1 |
| DiGiovanni, J; Elmer, GW; Meadows, GG; Minor, L | 1 |
| Larsson, LE; Melin, P; Ragnarsson, U | 1 |
| Chawla, RK; Gaby, AR | 1 |
| Biggart, JD; Bittles, AH; Carson, NA; Donovan, D | 1 |
| Bach, D; Miller, IR | 1 |
| Roberts, J; Schmid, FA; Takai, K | 1 |
| Kalghatgi, KK; Subba Rao, PV | 1 |
| Baillie, RD; Horowitz, PM | 1 |
| Friedman, SM; Miller, HM | 1 |
| Elsden, SR; Hilton, MG; Waller, JM | 1 |
| Das, A; Vogel, AM | 1 |
| Canessa, CM; Horisberger, JD; Louvard, D; Rossier, BC | 1 |
| Koppenol, WH; Maskos, Z; Rush, JD | 1 |
| Kahn, CR; Siddle, K; White, MF; Wilden, PA | 1 |
| Gotoh, N; Hino, M; Shibuya, M; Tojo, A; Yazaki, Y | 1 |
| Anthony, E; Beardsley, PM; Chandrakumar, NS; Drury, B; Lopez, OT; Reichman, M; Savage, MA; Stapelfeld, A; Williamson, LN | 1 |
| Kroona, HB; Mosberg, HI | 1 |
| Giraud, F; Maurin, N; Sarles, J | 1 |
| Shintaku, H | 1 |
| Economou-Petersen, E; Guldberg, P; Güttler, F; Henriksen, KF | 1 |
| Burke, GT; Chu, YC; Katsoyannis, PG; Zong, L | 1 |
| Enei, H; Ito, H; Sakurai, S; Sato, K; Tanaka, T | 1 |
| Lewis, RV; Mach, H; Middaugh, CR | 1 |
| Durieux, C; Ficheux, D; McCort-Tranchepain, I; Roques, BP | 1 |
| Hjalmarson, O; Holme, E; Lindstedt, S; Lock, EA; Strandvik, B | 1 |
| Ingram, RL; Lenham, JE; Sonntag, WE | 1 |
| Baudin, V; Bihoreau, MT; Kiger, L; Kister, J; Lacaze, N; Marden, M; Pagnier, J; Poyart, C | 1 |
| Sakurai, T; Takanashi, M; Tsuchiya, S | 1 |
| Barron, JL; Madira, WM; Stern, J; Wilcox, AH; Xavier, F | 1 |
| Kato, A; Sato, S; Suzuki, K | 1 |
| Kadowaki, M; Mortimore, GE; Pösö, AR | 1 |
| Brearley, GM; Campbell, RS; Hall, SK; Hammond, PM; Milligan, TP; Morris, HC; Price, CP; Varsani, H | 1 |
| Blomstrand, E; Newsholme, EA | 1 |
| al-Awadi, SA; al-Ghanim, MM; al-Najdi, K; el-Badramany, MH; Farag, TI; Girish, Y; Uma, R; Usha, R | 1 |
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| FRIDDLE, SB; GRIFFIN, PJ; SNIESZKO, SF | 1 |
| BICKEL, H; BOSCOTT, RJ | 1 |
| SALONNA, F | 1 |
| CLARK-LEWIS, JW; FRUTON, JS | 1 |
| GRAU, CR; STEELE, R | 1 |
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| ROSE, WC; WIXOM, RL | 1 |
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| GRABAR, P; PRUDHOMME, RO; ROBERT, B | 1 |
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| HUISMAN, TH; JONXIS, JH | 2 |
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| Kataoka, N; Matsushita, K; Matsutani, M; Yakushi, T | 1 |
| Emerson, JP; Fitzpatrick, PF; Li, M; Subedi, BP | 1 |
| Gao, LM; Liu, GY; Wang, HL; Wassie, T; Wu, X; Yin, YL | 1 |
| Cheng, J; Liu, J; Liu, S; Liu, Y; Ma, T; Sun, X; Wang, L; Wen, J; Wen, Q; Wu, J; Xie, Y; Zhou, J; Zou, J | 1 |
| Cheng, Y; Guo, Y; Jiang, W; Liu, C; Qian, H; Yang, F; Yao, W; Zhao, Y | 1 |
| Esquivel-Alvarado, D; Hu, C; Sang, S; Zhang, S; Zhao, Y | 1 |
| Chen, Y; Huang, N; Lei, M; Li, G; Li, Y; Liu, Z; Mencius, J; Peng, C; Quan, S; Shi, P; Tian, C; Wang, X; Wu, P; Xu, W; Xu, Y; Ye, X; Zhang, Y; Zhao, L; Zheng, Y | 1 |
| Gohlke, H; Jayaraman, K; Sprenger, GA; Trachtmann, N | 1 |
| Gu, Y; Ling, S; Liu, J; Qiu, H; Wang, W; Xu, J; Yu, J; Zeng, X | 1 |
| Blanco-Esperguez, K; Kästner, J; Mendizábal, F; Miranda-Rojas, S; Tuñón, I | 1 |
| Beckmann, B; Blau, LS; Dimina, L; Finkel, A; Jantz, M; Lützow, M; Maassen, N; Mariotti, F; Röhrig, MA; Shushakov, V; Thorns, A; Tsikas, D | 1 |
| Ding, T; Gao, L; Ge, J; Gu, Q; Ma, X; Shen, W; Wang, H; Xue, F; Zhang, X | 1 |
| DI, LQ; Huang, X; Lu, YY; Luo, ZC; Qi, MY; Shan, JJ; Zhang, W | 1 |
| Chen, JY; He, Y; Li, YJ; Liu, CH; Lu, Y; Song, ZJ; Wang, YL; Zhu, XQ | 1 |
| Arnoux, JB; Bou-Gharios, G; Davison, AS; Gallagher, JA; Hughes, AT; Imrich, R; M, K; Milan, AM; Norman, BP; Olsson, B; Ranganath, LR; Rudebeck, M | 1 |
| Bai, Y; Chen, Y; Cheng, B; Liu, Y; Xu, S; Yang, X | 1 |
| Davis, SE; Lin, S; Martinez-Muniz, GA; Porter, KD; Quizon, PM; Strauss, MJ; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J | 1 |
| Bazotte, RB; Fregonesi, N; Martins, LG; Tasic, L; Visentainer, JEL | 1 |
| Fischer, M; Görlich, D; Huyton, T; Jaiswal, M; Taxer, W | 1 |
| Cai, H; Cai, Z; Chen, T; He, J; Jiang, J; Liu, Y; Xiao, S; Xie, T | 1 |
| Jia, W; Shi, L; Wang, X | 1 |
| Akbarian, S; Kompany-Zareh, M; Najafpour, MM | 1 |
| Chen, Q; Hou, L; Li, G; Lin, R; Pan, J; Wang, P; Wang, X; Zhao, J; Zhu, X | 1 |
| Ding, Y; Jiang, W; Liu, Z; Luo, S; Weng, J; Xu, M; Xu, W; Yan, J; Yang, D; Yue, T; Zheng, X | 1 |
| Chawla, N; Dhatt, AS; Sharma, H | 1 |
| Brito, F; Curcio, HFQ; da Silva Fidalgo, TK | 1 |
| Abdel Rahman, AM; Al-Ansari, MM; Alabdaljabar, MS; Dahabiyeh, LA; Housien, M; Jacob, M; Nimer, RM; Sabi, EM; Sumaily, KM | 1 |
| Ahmad, H; Ahmad, N; Chen, M; Du, J; Jin, Y; Khan, A; Li, X; Ouyang, Y; Tian, Z; Yang, P; Yang, Z; Zeng, L; Zhao, X; Zheng, X | 1 |
| Basso, E; Füchtbauer, A; Füchtbauer, EM; Jensen, PH; Lassen, LB; Moos, T; Outeiro, TF; Thomsen, MS | 1 |
| Ai, X; Bao, WM; Dang, FT; Feng, J; Fu, HY; Gupta, AK; Ma, HT; Manandhar, LK; Tan, X; Tang, YM; Tu, RF; Xu, JM; Yang, WX; Yu, HY | 1 |
| An, J; Jia, X; Li, X; Liu, R; Liu, S; Mo, Y; Wei, X; Zhang, S; Zhang, Y; Zhou, L | 1 |
| Guo, L; Huang, Y; Kong, X; Liu, P; Yu, X; Yu, Y; Zephania, HM | 1 |
| Chen, Y; Kang, C; Liang, YM; Wang, FX; Yang, M | 1 |
| Akke, M; Weininger, U | 1 |
| Cheng, J; Feng, X; Gao, Y; Lei, Z; Lian, H; Liang, J; Liu, Q; Liu, Z; Nong, Y; Song, F; Su, Y; Su, Z; Xian, Y; Zhao, J; Zhao, T | 1 |
| Ban, Q; Hou, YY; Huang, T; Ma, B; Shi, L; Zhang, ML; Zhang, Q; Zhou, YF | 1 |
| Bana, J; Bayer, EA; Livnah, O; Warwar, J | 1 |
| Liu, Y; Westerhoff, HV | 1 |
| Diao, M; Li, J; Meng, L; Peng, L; Wang, Q; Xie, N | 1 |
| Hiefinger, C; Kneuttinger, A; Mandl, S; Wieland, M | 1 |
| Han, L; Sun, H; Sun, J; Wang, Y; Xu, D; Xu, Y; Zhang, B | 1 |
| An, Y; Bai, Y; Cai, B; Dai, X; Fan, F; Li, X; Liu, M; Xu, S; Zhang, J; Zhao, H; Zou, Y | 1 |
| Arlien-Søborg, MC; Dal, J; Høgild, ML; Jessen, N; Jørgensen, JOL; Madsen, MA; Møller, N; Pedersen, SB | 1 |
| Armentrout, PB; Berden, G; Martens, J; Oomens, J; Stevenson, BC | 1 |
| Cai, K; Cao, W; Cheng, LL; Lin, Y; Shen, YH; Tao, H; Xiang, J; Xu, W; Yang, JJ; Yuan, YY; Zang, WD; Zhao, JY; Zhao, R; Zhao, SM; Zhou, Q | 1 |
| Auler, PA; Bianchi, VJ; Braga, EJB; da Silva Dos Santos, J; do Amaral, MN; Furlan, VJM; Lucho, SR; Milech, C | 1 |
| Balasubramaniam, S; Bandodkar, S; Devanapalli, B; Junek, R; Kim, WT; Mohammad, S; Parayil Sankaran, B; Wong, RSH; Wotton, T | 1 |
| da Silva, N; Kofler, F; Sieberichs, A; Wierckx, N; Wynands, B | 1 |
| Das, AK; Dutta, G; Kumar, MS; M, VC; Mukherjee, B; N, K; Rao, NP; S, V | 1 |
| Cryle, MJ; Goldfinger, V; Kulik, A; Link, H; Rapp, J; Rodler, JP; Sigle, M; Spohn, M; Stegmann, E; Wohlleben, W | 1 |
| Chen, F; Feng, Y; Jiang, Y; Li, S; Liu, X; Liu, Y; Zeng, Q; Zou, L | 1 |
| Han, M; Hao, YX; Li, Y; Liu, TT; Ma, L; Niu, XX; Wan, G; Xing, HC; Xu, YF; Yuan, XX; Zhang, MH; Zhang, YY | 1 |
| Esser, N; Kneipp, J; Plaickner, J; Spedalieri, C; Speiser, E | 1 |
| Chen, R; Gao, S; Liu, L; Liu, X; Zhao, J | 1 |
| Bruckner, T; Deisenhammer, EA; Egeter, J; Galffy, M; Giesinger, JM; Gostner, JM; Holzner, B; Hüfner, K; Lehmann, J; Nelles, P; Oberhammer, M; Rockenschaub, J; Sacher, M; Sperner-Unterweger, B; Tymoszuk, P; Vedova, S | 1 |
| Lombó, F; Magadán-Corpas, P; Pérez-Valero, Á; Villar, CJ; Ye, S | 1 |
| Chace, DH; Garrett, TJ; Li, W | 1 |
| Bavan, T; Binz, E; Irmler, S; Portmann, R | 1 |
| Kulkarni, M; Söderhjelm, P | 1 |
| Bornscheuer, UT; Brack, Y; Sun, C; Yi, D | 1 |
| Balcer, E; Bulska, E; Giebułtowicz, J; Muszyńska, M; Ruszczyńska, A; Sochacka, M | 1 |
| Birkeland, E; Haavik, J; Kleppe, R; Patil, S; Szigetvari, PD | 1 |
| Cho, SH; Choi, HK; Kim, JS; Kim, KK; Kim, MG; Koo, BS; Lee, YB; Liu, QF; Ryu, JE; Shin, SJ | 1 |
| Chen, X; El-Azaz, J; Maeda, HA; Moore, B; Schneider, M; Takeda-Kimura, Y; Wijesingha Ahchige, M; Yokoyama, R | 1 |
| Bhatt, L; Dhaneshwar, SS; Gairola, N; Kadam, SS; Kandpal, M; Rathi, B; Vadnerkar, G | 1 |
141 review(s) available for phenylalanine and tyrosine
| Article | Year |
|---|---|
Regulation of aromatic amino acid biosynthesis in microorganisms.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Amino Acids; Anthranilate Synthase; Bacteria; Chorismate Mutase; Fungi; Herbicides; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Tryptophan; Tyrosine | 1976 |
Effects on the diet on brain neurotransmitters.
Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Catecholamines; Choline; Choline Deficiency; Diet; Dietary Proteins; Fatty Acids, Nonesterified; Hydroxyindoleacetic Acid; Insulin; Neurotransmitter Agents; Pain; Phenylalanine; Protein Binding; Rats; Serotonin; Serum Albumin; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 1977 |
[Variation of plasma amino acids in severe hepatitis with encephalopathy 10 cases].
Topics: Acute Disease; Adult; Aged; Amino Acids; Binding, Competitive; Blood-Brain Barrier; Brain; Brain Diseases; Female; Hepatitis; Humans; Hydroxylation; Isoleucine; Leucine; Male; Middle Aged; Neurotransmitter Agents; Phenylalanine; Tyrosine; Valine | 1977 |
Biosynthesis of polyene macrolide antibiotics.
Topics: Acetyl-CoA Carboxylase; Acyl Coenzyme A; Amino Sugars; Antifungal Agents; Chemical Phenomena; Chemistry; Fatty Acids; Mycoses; Nucleoside Diphosphate Sugars; Phenylalanine; Streptomyces; Tryptophan; Tyrosine | 1977 |
Protein triplet states.
Topics: Electron Spin Resonance Spectroscopy; Energy Transfer; Indoles; Kinetics; Luminescent Measurements; Mathematics; Peptides; Phenylalanine; Protein Conformation; Proteins; Quantum Theory; Solvents; Temperature; Tryptophan; Tyrosine | 1975 |
Photochemistry of proteins.
Topics: Benzene Derivatives; Chemical Phenomena; Chemistry; Coloring Agents; Electron Spin Resonance Spectroscopy; Lasers; Light; Nucleic Acids; Oxidation-Reduction; Oxygen; Phenylalanine; Photochemistry; Photolysis; Proteins; Spectrum Analysis; Tryptophan; Tyrosine | 1975 |
The effect of dietary restriction on macrophage function evaluated by 125I-polyvinyl pyrrolidone clearance.
Topics: Amino Acids; Animals; Dietary Proteins; Female; Immunity; Macrophages; Male; Mice; Mononuclear Phagocyte System; Phagocytosis; Phenylalanine; Povidone; Protein Deficiency; Sex Factors; Species Specificity; Tryptophan; Tyrosine | 1977 |
Amino acid biosynthesis and its regulation.
Topics: Amino Acids; Arginine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Histidine; Phenylalanine; Pyruvates; Serine; Tyrosine | 1978 |
The justification theory: the essential nature of the non-essential amino acids.
Topics: Amino Acids; Diet; Humans; Intellectual Disability; Intelligence; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Tyrosine; United States | 1979 |
[Diagnosis and therapy of 6 inherited, metabolic diseases, leading to mental deficiency. 1].
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Heterozygote; Humans; Infant, Newborn; Infant, Newborn, Diseases; Intelligence Tests; Mass Screening; Mental Disorders; Phenylalanine; Phenylketonurias; Tyrosine | 1976 |
[Biochemical aspects of the use of amino acid mixtures in parenteral feeding (review of the literature)].
Topics: Age Factors; Amino Acids; Arginine; Cystine; Histidine; Humans; Methionine; Parenteral Nutrition; Phenylalanine; Tyrosine | 1975 |
Biomarkers of OH radical damage in vivo.
Topics: Biomarkers; DNA; Free Radicals; Hydroxides; Hydroxyl Radical; Hydroxylation; Phenylalanine; Proteins; Thymine; Thymine Nucleotides; Tyrosine | 1991 |
Aromatic amino acid biosynthesis in the yeast Saccharomyces cerevisiae: a model system for the regulation of a eukaryotic biosynthetic pathway.
Topics: Base Sequence; DNA, Fungal; Enzymes; Molecular Sequence Data; Phenylalanine; Saccharomyces cerevisiae; Transcription, Genetic; Tryptophan; Tyrosine | 1991 |
Phenylalanine and tyrosine metabolism in renal failure: dipeptides as tyrosine source.
Topics: Animals; Dipeptides; Kidney Failure, Chronic; Parenteral Nutrition; Phenylalanine; Tyrosine | 1989 |
Progress in the identification of the heterozygote in phenylketonuria.
Topics: Breath Tests; Fasting; Female; Genetic Carrier Screening; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Polymorphism, Restriction Fragment Length; Pregnancy; Prenatal Diagnosis; Tyrosine | 1989 |
The control of aromatic amino acid catabolism and its relationship to neurotransmitter amine synthesis.
Topics: Amino Acids; Animals; Biogenic Amines; Brain; Humans; Liver; Neurotransmitter Agents; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Septic encephalopathy. Etiology and management.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Brain; Brain Diseases; Guinea Pigs; Humans; Infections; Neurotransmitter Agents; Phenylalanine; Rats; Toxins, Biological; Tryptophan; Tyrosine | 1986 |
[Plasma-cerebrospinal fluid distribution of phenylalanine and tyrosine in children].
Topics: Blood-Brain Barrier; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Meningoencephalitis; Phenylalanine; Tyrosine | 1988 |
Review of current practices in management of inherited disorders of amino acid metabolism in Western Europe.
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Biopterins; Diet; Dietary Proteins; Dihydropteridine Reductase; Europe; Female; Glucosephosphate Dehydrogenase Deficiency; Humans; Infant; Infant, Newborn; Intellectual Disability; Liver; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Prognosis; Pterins; Tyrosine | 1986 |
Neurotoxicology of food additives.
Topics: Animals; Aspartame; Blood-Brain Barrier; Dietary Carbohydrates; Dietary Proteins; Dipeptides; Emotions; Female; Food Additives; Maximum Allowable Concentration; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Seizures; Sleep Initiation and Maintenance Disorders; Tyrosine; United States; United States Food and Drug Administration | 1986 |
Regulation of aromatic amino acid catabolism.
Topics: Amino Acids; Animals; Biological Transport, Active; Liver; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1986 |
Dietary D-tyrosine as an antimetabolite in mice.
Topics: Animals; Antimetabolites; Mice; Nutritive Value; Phenylalanine; Poultry; Rats; Tyrosine | 1985 |
Biochemical basis for nutritional management of preterm infants.
Topics: Acetoacetates; Adenosine Triphosphate; Amino Acids; Animals; Brain; Cyclic AMP; Cystathionine; Cystine; Enzyme Induction; Female; Fumarates; Homogentisic Acid; Humans; Hydro-Lyases; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Liver; Lyases; Maternal-Fetal Exchange; Methionine; Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pregnancy; S-Adenosylmethionine; Transferases; Tyrosine; Tyrosine Transaminase | 1974 |
Phenylalanine to tyrosine ratio in renal failure.
Topics: Adult; Age Factors; Animals; Child; Humans; Kidney; Kidney Failure, Chronic; Nephrectomy; Nutrition Disorders; Phenylalanine; Phenylalanine Hydroxylase; Rats; Tyrosine; Tyrosine Transaminase; Uremia | 1974 |
Amino acid metabolism.
Topics: Aldehyde-Lyases; Amino Acids; Animals; Bacteria; Biological Evolution; Biological Transport; Cyclohexanecarboxylic Acids; Enzyme Induction; Enzyme Repression; Enzymes; Escherichia coli; Genes; Genes, Regulator; Glutamate-Ammonia Ligase; Glutamates; Heptoses; Histidine; Mammals; Operon; ortho-Aminobenzoates; Phenylalanine; RNA, Transfer; Salmonella typhimurium; Transaminases; Tryptophan Synthase; Tyrosine | 1973 |
The regulation of the noradrenergic neuron.
Topics: Binding, Competitive; Catecholamines; Cell Membrane; Chromaffin System; Dihydroxyphenylalanine; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Exocytosis; Humans; Neurons; Norepinephrine; Phenylalanine; Sympathetic Nervous System; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
[Biochemical treatment possibilities in psychoses].
Topics: Amino Acids; Ascorbic Acid; Dihydroxyphenylalanine; Humans; Methionine; Niacinamide; Nicotinic Acids; Phenylalanine; Psychotic Disorders; Pyridoxine; Schizophrenia; Tryptophan; Tyrosine | 1969 |
Long-range nonradiative transfer of electronic excitation energy in proteins and polypeptides.
Topics: Adrenocorticotropic Hormone; Catalase; Chemical Phenomena; Chemistry, Physical; Coloring Agents; Copper; Dipeptides; Energy Transfer; Fluorescence; Glyceraldehyde-3-Phosphate Dehydrogenases; Hemocyanins; Hemoglobins; Indoles; Insulin; L-Lactate Dehydrogenase; Mathematics; Monoiodotyrosine; Myoglobin; NAD; Parathyroid Hormone; Peptides; Phenols; Phenylalanine; Phosphoric Acids; Picolines; Plant Proteins; Proteins; Pyridoxal Phosphate; Thyroxine; Transferrin; Tryptophan; Tyrosine | 1971 |
Genetic regulatory systems in Neurospora.
Topics: Aminoacylation; Aminobenzoates; Enzyme Induction; Enzyme Repression; Escherichia coli; Feedback; Genes; Genetics, Microbial; Glucosidases; Histidine; Leucine; Methionine; Mutation; Neurospora; Operon; Phenylalanine; Phosphoric Monoester Hydrolases; Quinic Acid; Salmonella; Sulfur; Tryptophan; Tyrosine | 1972 |
[Transitory hypertyrosinemia of young infants and its relation to vitamin C].
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Ascorbic Acid; Guinea Pigs; Humans; Infant, Newborn; Infant, Premature, Diseases; Liver; Mixed Function Oxygenases; Phenylalanine; Rats; Tyrosine; Tyrosine Transaminase | 1969 |
Photochemical reactions of natural macromolecules. Photoreactions of proteins.
Topics: Absorption; Amino Acids; Energy Transfer; Fluorescence; Neoplasms, Radiation-Induced; Peptides; Phenylalanine; Photochemistry; Proteins; Radiation Effects; Retinal Pigments; Skin Neoplasms; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Ultraviolet Rays | 1973 |
[Transitory disorders of amino acid metabolism. Practical viewpoints].
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Ascorbic Acid; Cystathionine; Diagnosis, Differential; Histidine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Infant, Premature, Diseases; Male; Metabolic Diseases; Methionine; Milk Proteins; Phenylalanine; Rats; Testicular Diseases; Time Factors; Tyrosine | 1973 |
Synthetic analogs of oxytocin and the vasopressins.
Topics: Amino Acids; Animals; Anura; Asparagine; Cystine; Hypothalamus; In Vitro Techniques; Oxytocin; Peptide Chain Termination, Translational; Peptides; Phenylalanine; Proline; Rats; Receptors, Drug; Structure-Activity Relationship; Tyrosine; Vasopressins | 1973 |
Utilization of D- and DL- amino acids and analogs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Histidine; Isomerism; Keto Acids; Leucine; Methionine; Nutritional Requirements; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1972 |
Aminoacidurias due to inherited disorders of metabolism (first of two parts).
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Child; Cystathionine; Cysteine; Cystine; Disulfides; Female; Homocystinuria; Humans; Infant, Newborn; Lactates; Male; Methionine; Oxidoreductases; Phenylalanine; Phenylketonurias; Pregnancy; Pyruvates; Sulfhydryl Compounds; Sulfites; Sulfur; Tyrosine | 1973 |
Conformational analysis of aromatic amino acids by x-ray crystallography.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Molecular Conformation; Optical Rotation; Phenylalanine; Tyrosine; X-Ray Diffraction | 1973 |
Genetic screening.
Topics: Amino Acid Metabolism, Inborn Errors; Anemia, Sickle Cell; Arginine; Carbohydrate Metabolism, Inborn Errors; Cystinuria; Erythrocytes; Fanconi Syndrome; Galactosemias; Genetics, Population; Glucosephosphate Dehydrogenase; Glycine; Hartnup Disease; Heterozygote; Histidine; Homocystine; Humans; Lysine; Maple Syrup Urine Disease; Mass Screening; Methods; Ornithine; Phenylalanine; Phenylketonurias; Succinates; Tyrosine | 1973 |
Neonatal screening for inborn errors of amino acid metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Biological Assay; Chromatography, Paper; Evaluation Studies as Topic; Female; Hartnup Disease; Histidine; Homocystinuria; Humans; Infant, Newborn; Leucine; Maple Syrup Urine Disease; Mass Screening; Methionine; Methods; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1974 |
[Biosynthesis of alkaloids].
Topics: Alkaloids; Indoles; Isoquinolines; Phenylalanine; Plants; Terpenes; Tryptophan; Tyrosine | 1974 |
Genetics of amino acid transport in bacteria.
Topics: Alanine; Amino Acids; Amino Acids, Diamino; Arginine; Asparagine; Aspartic Acid; Biological Transport; Cell Membrane Permeability; Cystine; Energy Metabolism; Escherichia coli; Genes, Regulator; Genetics, Microbial; Glutamates; Glutamine; Glycine; Histidine; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Biosynthesis of glucosinolates.
Topics: Acetates; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Paper; Glucose; Methionine; Nitriles; Nitrogen Isotopes; Phenylalanine; Plants; Thioglycosides; Tritium; Tryptophan; Tyrosine | 1973 |
Biosynthesis of cyanogenic glycosides.
Topics: Amino Acids; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Cyanides; Disaccharides; Genetics; Glycosides; Hydrogen Cyanide; Lyases; Mandelic Acids; Nitriles; Nitrogen Isotopes; Oximes; Oxygen Isotopes; Phenylalanine; Plants; Plants, Edible; Species Specificity; Structure-Activity Relationship; Tyrosine; Valine | 1973 |
Microbial production of amino acids.
Topics: Amino Acids; Bacteria; Biotin; Chemical Industry; Glutamates; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[Structure of transfer RNA].
Topics: Alanine; Chemical Phenomena; Chemistry; Phenylalanine; RNA, Transfer; Serine; Tyrosine; Valine | 1967 |
Some aspects of amino acid biosynthesis in microorganisms.
Topics: Amino Acids; Aspartic Acid; Bacteria; Enterobacteriaceae; Escherichia coli; Glutamine; Isoleucine; Neurospora; Phenylalanine; Rhodopseudomonas; Tryptophan; Tyrosine; Valine | 1968 |
Toxic amino acids: their action as antimetabolites.
Topics: Alkaline Phosphatase; Amino Acids; Antimetabolites; Arginine; Biological Transport, Active; Drug Resistance, Microbial; Enzyme Repression; Escherichia coli; Ethionine; Histidine; Hot Temperature; Methionine; Nucleic Acids; Phenylalanine; Plants, Medicinal; Proline; Protein Biosynthesis; Pseudomonas; Saccharomyces; Selenium; Tryptophan; Tyrosine | 1967 |
Control of amino acid biosynthesis in microorganisms.
Topics: Amino Acids; Aspartic Acid; Chromosome Mapping; Enzyme Repression; Escherichia coli; Genetics, Microbial; Histidine; Phenylalanine; Salmonella typhimurium; Tryptophan; Tyrosine | 1968 |
[Molecular biologic aspects in dermatology demonstrated by some hereditary enzyme defects].
Topics: Albinism; Alkaptonuria; Anemia, Sickle Cell; Chromosomes; Hartnup Disease; Humans; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Models, Chemical; Molecular Biology; Phenylalanine; Phenylketonurias; Porphyrias; Skin Diseases; Tyrosine | 1968 |
Regulation of amino acid metabolism.
Topics: Amino Acids; Aspartic Acid; Bacteria; Enzyme Repression; Enzymes; Glutamates; Histidine; Models, Biological; Molecular Biology; Phenylalanine; Pyruvates; Serine; Tryptophan; Tyrosine | 1969 |
The measurement of phenylalanine and tyrosine in blood.
Topics: Adult; Biological Assay; Child, Preschool; Fluorometry; Humans; Indicators and Reagents; Infant; Infant, Newborn; Metabolism, Inborn Errors; Methods; Microchemistry; Middle Aged; Naphthalenes; Nitroso Compounds; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
[Problems around phenylketonuria].
Topics: Diet Therapy; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intellectual Disability; Intelligence Tests; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
[Multiplicity and specificity in code recognition of tRNA against specific amino acid].
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Cystine; Escherichia coli; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Leucine; Liver; Lysine; Phenylalanine; Rabbits; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Serine; Threonine; Tyrosine; Yeasts | 1969 |
The biosynthesis and metabolism of the catecholamines.
Topics: Alcohol Oxidoreductases; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Dopa Decarboxylase; Dopamine; Epinephrine; Humans; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Phenethylamines; Phenylalanine; Radioisotopes; Schizophrenia; Transferases; Tyrosine; Vanilmandelic Acid | 1969 |
Measurement of phenylalanine hydroxylase activity in mammalian cells.
Topics: Animals; Carbon Isotopes; Cell Biology; Culture Techniques; Genotype; Heterozygote; Homozygote; Humans; Intestines; Kidney; Kinetics; Liver; Lung; Mice; Mixed Function Oxygenases; Muscles; Myocardium; Pancreas; Phenylalanine; Phenylketonurias; Spleen; Tyrosine | 1969 |
[Tyrosinosis].
Topics: Deficiency Diseases; Humans; Infant; Infant, Newborn; Liver Cirrhosis; Metabolism, Inborn Errors; Phenylalanine; Pyruvate Oxidase; Tyrosine | 1969 |
Adrenergic mechanisms in the sinus node.
Topics: Animals; Chemoreceptor Cells; Dihydroxyphenylalanine; Dogs; Dopamine; Epinephrine; Humans; Isoproterenol; Norepinephrine; Phenylalanine; Pulse; Sinoatrial Node; Sympathetic Nervous System; Sympatholytics; Sympathomimetics; Tyrosine; Vasoconstrictor Agents | 1970 |
Photochemical reactions in amino acid residues and inactivation of enzymes during U.V.-irradiation. A review.
Topics: Amino Acids; Cystine; Enzymes; Light; Luminescence; Oxidation-Reduction; Phenylalanine; Proteins; Spectrophotometry; Sulfur; Tryptophan; Tyrosine; Ultraviolet Rays | 1970 |
Effects of ingestion of disproportionate amounts of amino acids.
Topics: Adaptation, Physiological; Age Factors; Amino Acids; Ammonia; Animals; Cystine; Deficiency Diseases; Feeding Behavior; Glycine; Growth Disorders; Histidine; Homeostasis; Humans; Leucine; Liver; Lysine; Methionine; Nicotinic Acids; Nutrition Disorders; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine | 1970 |
Phenylketonuria and its variants.
Topics: Adult; Child, Preschool; Congenital Abnormalities; Female; Gene Frequency; Growth Disorders; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Middle Aged; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1970 |
Amino acid intoxication.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Benzyl Compounds; Biological Transport, Active; Brain; Caseins; Chickens; Cytoplasm; Endoplasmic Reticulum; Fasting; Feeding Behavior; Glutathione; Growth; Humans; Injections, Intraperitoneal; Leucine; Liver; Methionine; Microsomes; Mitochondrial Swelling; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Protein Biosynthesis; Rats; Tyrosine | 1971 |
Metabolic modification of Parkinson's disease and of chronic manganese poisoning.
Topics: Animals; Brain; Choline; Chronic Disease; Dihydroxyphenylalanine; Drug Synergism; Humans; Manganese Poisoning; Melatonin; Methionine; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenylalanine; Poisoning; Pyridoxine; Tryptophan; Tyrosine | 1971 |
Growth and nutrition in treated phenylketonic patients.
Topics: Child; Child Nutritional Physiological Phenomena; Circadian Rhythm; Diet Therapy; Dietary Proteins; Growth; Humans; Phenylalanine; Phenylketonurias; Proteins; Tyrosine | 1970 |
Formation and biological degradation of lignins.
Topics: 1-Propanol; Carbon Dioxide; Carbon Isotopes; Cell Wall; Chemical Phenomena; Chemistry; Cinnamates; Ethers; Flavoring Agents; Fungi; Guaifenesin; Lignin; Lyases; Methionine; Methyltransferases; Phenylalanine; Plants; Polysaccharides; Shikimic Acid; Transaminases; Trees; Tyrosine; Wood | 1971 |
Some questions about the structure and activity of aminoacyl-tRNA synthetases.
Topics: Amino Acid Sequence; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Base Sequence; Binding Sites; Cations, Divalent; Inosine; Isoleucine; Isomerism; Kinetics; Methionine; Methylation; Molecular Weight; Nucleic Acid Conformation; Oligonucleotides; Phenylalanine; Protein Binding; Pseudouridine; Ribonucleotides; RNA, Transfer; Species Specificity; Sulfhydryl Compounds; Sulfur; Tyrosine; Uracil; Valine | 1971 |
Biochemical factors in mental retardation.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Diet Therapy; Female; Guinea Pigs; Haplorhini; Humans; Infant; Intellectual Disability; Intelligence Tests; Male; Metabolism, Inborn Errors; Monoamine Oxidase; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan; Tyrosine | 1967 |
The biosynthesis of aromatic amino acids and its regulation.
Topics: Amino Acids; Aminobenzoates; Enterobacter; Escherichia coli; Folic Acid; Neurospora; Nicotinic Acids; Phenylalanine; Salmonella typhimurium; Tryptophan; Tyrosine; Vitamin K; Yeasts | 1968 |
[Study on experimental phenylketonuria].
Topics: Amino Acids; Animals; Brain; Female; Haplorhini; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Tyrosine | 1968 |
[Tyrosine hydroxylase].
Topics: Animals; Brain; Catechol Oxidase; Catecholamines; Coenzymes; Heart; Humans; Hypertension; Mixed Function Oxygenases; Phenylalanine; Tyrosine | 1969 |
[Biochemical basis of parenteral feeding with amino acids].
Topics: Amino Acids; Homeostasis; Liver; Methionine; Muscles; Nutritional Physiological Phenomena; Parenteral Nutrition; Phenylalanine; Tryptophan; Tyrosine | 1971 |
Metabolite analogs as genetic and biochemical probes.
Topics: Amino Acids; Bacillus subtilis; Drug Resistance, Microbial; Escherichia coli; Genes; Genes, Regulator; Genetics, Microbial; Histidine; Isoleucine; Leucine; Models, Biological; Molecular Biology; Mutation; Operon; Phenylalanine; Salmonella typhimurium; Tryptophan; Tyrosine; Valine | 1971 |
The metabolism of aromatic compounds.
Topics: Animals; Insecta; Kynurenine; Melanins; Phenylalanine; Quinones; Tyrosine | 1965 |
Adverse effects of excessive consumption of amino acids.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Cattle; Diet; Disease Models, Animal; Ethionine; Fenclonine; Glycine; Growth Disorders; Histidine; Humans; Methionine; Nerve Tissue Proteins; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pneumonia, Atypical Interstitial, of Cattle; Serine; Stereoisomerism; Sulfhydryl Compounds; Tissue Distribution; Tryptophan; Tyrosine; Vitamin A | 1984 |
Structure-CNS activity studies with the enkephalins.
Topics: Analgesia; Animals; Brain; Endorphins; Enkephalins; Glycine; Methionine; Phenylalanine; Receptors, Opioid; Structure-Activity Relationship; Tyrosine | 1980 |
[Synthetic enkephalins and multiple opiate receptors].
Topics: Animals; Enkephalins; Guinea Pigs; Mice; Phenylalanine; Rats; Receptors, Opioid; Structure-Activity Relationship; Swine; Tyrosine | 1983 |
Amino acid degradation by anaerobic bacteria.
Topics: Amino Acids; Anaerobiosis; Aspartic Acid; Clostridium; Culture Media; Glutamates; Glycine; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Species Specificity; Threonine; Tryptophan; Tyrosine; Valine | 1981 |
In vivo chemical modification of proteins (post-translational modification).
Topics: Amino Acids; Animals; Arginine; Asparagine; Aspartic Acid; Glutamates; Glutamine; Histidine; Hydroxylysine; Lysine; Phenylalanine; Proline; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Serine; Threonine; Tryptophan; Tyrosine | 1981 |
A survey of inborn errors of amino acid metabolism and transport in man.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Amino Acids, Branched-Chain; Biological Transport; Cystinosis; Female; Glutathione; Glycine; Homocystinuria; Humans; Hydroxyproline; Infant; Infant, Newborn; Lysine; Maple Syrup Urine Disease; Phenylalanine; Proline; Serine; Tyrosine; Urea; Valine | 1981 |
Neonatal screening tests.
Topics: Adenosine Deaminase; Anemia, Sickle Cell; Biological Assay; Costs and Cost Analysis; Galactosemias; Histidine; Homocystinuria; Humans; Infant, Newborn; Maple Syrup Urine Disease; Mass Screening; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Tyrosine; United States | 1980 |
Dopamine precursors and brain function in phenylalanine hydroxylase deficiency.
Topics: Brain Chemistry; Clinical Trials as Topic; Cross-Over Studies; Dopamine; Double-Blind Method; Electroencephalography; Humans; Neuropsychological Tests; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1994 |
Cation-pi interactions in chemistry and biology: a new view of benzene, Phe, Tyr, and Trp.
Topics: Acetylcholine; Benzene; Binding Sites; Cations; Chemical Phenomena; Chemistry, Physical; Ion Channels; Phenylalanine; Proteins; Receptors, Cholinergic; Steroids; Tryptophan; Tyrosine; Water | 1996 |
Biocatalytic syntheses of aromatics from D-glucose: renewable microbial sources of aromatic compounds.
Topics: Amino Acids; Biotransformation; Chemistry, Organic; Glucose; Phenylalanine; Tryptophan; Tyrosine | 1995 |
A comparison of the transmembrane domains of Golgi and plasma membrane proteins.
Topics: Amino Acids; Cell Membrane; Golgi Apparatus; Membrane Proteins; Molecular Structure; Phenylalanine; Tryptophan; Tyrosine | 1995 |
Evidence for the importance of dopamine for prefrontal cortex functions early in life.
Topics: Animals; Child, Preschool; Cognition; Disease Models, Animal; Dopamine; Humans; Infant; Inhibition, Psychological; Macaca; Neural Pathways; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Spatial Behavior; Task Performance and Analysis; Tyrosine; Visual Pathways | 1996 |
The various strategies within the TyrR regulation of Escherichia coli to modulate gene expression.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Bacterial Proteins; Base Sequence; Carrier Proteins; DNA-Directed RNA Polymerases; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Phenylalanine; Promoter Regions, Genetic; Regulon; Repressor Proteins; Transcription Factors; Transcription, Genetic; Tryptophan; Tyrosine | 1996 |
Ochronotic arthropathy: the black hip. Case report and review of the literature.
Topics: Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Cartilage, Articular; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Ochronosis; Osteoarthritis; Phenylalanine; Tyrosine | 1997 |
[Alkaptonuria (homogentisic aciduria)].
Topics: Alkaptonuria; Arthritis; Diagnosis, Differential; Dioxygenases; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Humans; Ochronosis; Oxygenases; Phenylalanine; Tyrosine | 1998 |
[Inborn errors of tyrosine metabolism: abnormalities in catabolic pathway of phenylalanine and tyrosine].
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acetoacetates; Amino Acid Metabolism, Inborn Errors; Animals; Humans; Mice; Mutation; Phenylalanine; Tyrosine; Tyrosinemias | 1999 |
A review of recent advances on the regulation of pigmentation in the human epidermis.
Topics: Albinism, Oculocutaneous; alpha-MSH; Biopterins; Dihydroxyphenylalanine; Enzyme Activation; Epidermis; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Intramolecular Oxidoreductases; Keratinocytes; Melanocytes; Melanosomes; Membrane Glycoproteins; Membrane Proteins; Monophenol Monooxygenase; Oxidative Stress; Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Pro-Opiomelanocortin; Proteins; Racial Groups; Recombinant Fusion Proteins; Skin Pigmentation; Transfection; Tyrosine; Tyrosine 3-Monooxygenase; Vitiligo | 1999 |
Use of neurotransmitter precursors for treatment of depression.
Topics: 5-Hydroxytryptophan; Depression; Humans; Phenylalanine; Tryptophan; Tyrosine | 2000 |
Current total parenteral nutrition solutions for the neonate are inadequate.
Topics: Amino Acids; Cysteine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intestine, Small; Methionine; Nutritional Requirements; Parenteral Nutrition, Total; Phenylalanine; Solutions; Tyrosine | 2000 |
Phenylketonuria: tyrosine supplementation in phenylalanine-restricted diets.
Topics: Amino Acids; Circadian Rhythm; Diet; Dietary Supplements; Dose-Response Relationship, Drug; Female; Food, Fortified; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Taste; Tyrosine | 2001 |
Phenylketonuria: tyrosine beyond the phenylalanine-restricted diet.
Topics: Amino Acids, Neutral; Blood-Brain Barrier; Humans; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Tyrosine | 2001 |
The biosynthesis of shikimate metabolites.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Animals; Anthranilate Synthase; Bacteria; Betalains; Catalysis; Chorismate Mutase; Coumarins; Flavonoids; Hydro-Lyases; Indoleacetic Acids; Indoles; Intramolecular Transferases; Lignans; Molecular Structure; Penicillium; Phenylalanine; Phenylpropionates; Phosphorus-Oxygen Lyases; Prephenate Dehydratase; Prephenate Dehydrogenase; Pristinamycin; Pyrrolnitrin; Quaternary Ammonium Compounds; Quinones; Shikimic Acid; Staurosporine; Tannins; Thiazoles; Thyroxine; Tryptophan; Tyrosine; Ubiquinone | 2001 |
A fungal perspective on human inborn errors of metabolism: alkaptonuria and beyond.
Topics: Alkaptonuria; Animals; Aspergillus nidulans; Genes, Fungal; Humans; Metabolism, Inborn Errors; Models, Chemical; Mutation; Phenylalanine; Tyrosine | 2001 |
The metabolic conversion of phenylalanine into tyrosine in the human kidney: does it have nutritional implications in renal patients?
Topics: Dietary Proteins; Humans; Kidney; Kidney Failure, Chronic; Nutritional Requirements; Phenylalanine; Phenylalanine Hydroxylase; Renal Dialysis; Tyrosine | 2002 |
AMINO ACID METABOLISM.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carboxy-Lyases; Glutamates; Glycine; Hydroxyproline; Lysine; Peroxidases; Phenylalanine; Proline; Proteins; Pyridoxal Phosphate; Research; Serine; Threonine; Transaminases; Tryptophan; Tyrosine; Urea | 1963 |
INHERITED METABOLIC DISORDERS: ERRORS OF PHENYLALANINE AND TYROSINE METABOLISM.
Topics: Amino Acid Metabolism, Inborn Errors; Humans; Phenylalanine; Tyrosine | 1963 |
HISTIDINE, PHENYLALANINE, AND TYROSINE METABOLISM IN KWASHIORKOR.
Topics: Amino Acids; Histidine; Humans; Kwashiorkor; Phenylalanine; Tyrosine; Urine | 1965 |
Amino acid and protein metabolism in chronic renal failure.
Topics: Amino Acids; Animals; Humans; Kidney; Kidney Failure, Chronic; Kinetics; Mitochondria, Muscle; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Proteins; Tyrosine | 2005 |
Structural and sequence motifs of protein (histone) methylation enzymes.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Arginine; Binding Sites; Chromatin; Crystallography, X-Ray; Histone-Lysine N-Methyltransferase; Histones; Humans; Lysine; Mass Spectrometry; Methylation; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Proteins; Protons; Sequence Homology, Amino Acid; Tyrosine; Zinc | 2005 |
Decreased phenylalanine uptake and turnover in patients with vitiligo.
Topics: Adolescent; Adult; Calcium; Epidermis; Female; Humans; Male; Middle Aged; Phenylalanine; Tyrosine; Vitiligo | 2005 |
Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering.
Topics: Amino Acids, Aromatic; Corynebacterium glutamicum; Escherichia coli; Genetic Engineering; Phenylalanine; Tryptophan; Tyrosine | 2006 |
Protect from light: photodegradation and protein biologics.
Topics: Biological Products; Cystine; Drug Stability; Excipients; Phenylalanine; Photolysis; Proteins; Tryptophan; Tyrosine | 2007 |
Tyrosine, phenylalanine, and catecholamine synthesis and function in the brain.
Topics: Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Hydroxylation; Kinetics; Phenylalanine; Rats; Retina; Tyrosine | 2007 |
An overview of phenylalanine and tyrosine kinetics in humans.
Topics: Humans; Kinetics; Models, Biological; Oxidation-Reduction; Phenylalanine; Reproducibility of Results; Tyrosine | 2007 |
Aromatic amino acid metabolism during liver failure.
Topics: Amino Acids, Aromatic; Ammonia; Biological Transport; Humans; Liver Failure; Phenylalanine; Reference Values; Tryptophan; Tyrosine | 2007 |
Phenylalanine and tyrosine metabolism in chronic kidney failure.
Topics: Animals; Carbon Dioxide; Humans; Kidney Failure, Chronic; Kinetics; Models, Animal; Phenylalanine; Rats; Reference Values; Tyrosine | 2007 |
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
Topics: Animals; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydroxyl Radical; Mental Disorders; Neuroprotective Agents; Phenylalanine; Synaptic Transmission; Tyrosine | 2006 |
Recent progresses in protein-based chiral stationary phases for enantioseparations in liquid chromatography.
Topics: Animals; Chickens; Chromatography, Liquid; Glucan 1,4-alpha-Glucosidase; Humans; Immunoglobulin G; Models, Molecular; Orosomucoid; Penicillin Amidase; Phenoxyacetates; Phenylalanine; Serum Albumin; Stereoisomerism; Tyrosine | 2008 |
Effect of liver cirrhosis on phenylalanine and tyrosine metabolism.
Topics: Humans; Hydroxylation; Kidney; Liver; Liver Cirrhosis; Phenylalanine; Tyrosine | 2010 |
Recent advances in our understanding of protein and amino acid metabolism in the human fetus.
Topics: Albumins; Amino Acids; Biological Transport; Female; Fetus; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Prenatal Nutritional Physiological Phenomena; Proteins; Time Factors; Tyrosine | 2010 |
Tyrosine supplementation for phenylketonuria.
Topics: Dietary Supplements; Humans; Intelligence; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Randomized Controlled Trials as Topic; Tyrosine | 2010 |
Applications and modifications of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) in peptides and peptidomimetics design and discovery.
Topics: Drug Design; Peptides; Peptidomimetics; Phenylalanine; Proline; Tetrahydroisoquinolines; Tyrosine | 2010 |
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine | 2011 |
The shikimate pathway and aromatic amino Acid biosynthesis in plants.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Alkyl and Aryl Transferases; Amino Acids, Aromatic; Anthranilate Synthase; Biological Transport; Humans; Hydro-Lyases; Phenylalanine; Phosphorus-Oxygen Lyases; Phosphotransferases (Alcohol Group Acceptor); Plants; Shikimic Acid; Transcription, Genetic; Tryptophan; Tyrosine | 2012 |
The importance of the self-assembly process to control mechanical properties of low molecular weight hydrogels.
Topics: Dipeptides; Hydrogels; Hydrogen-Ion Concentration; Molecular Weight; Phenylalanine; Phosphates; Solvents; Tyrosine | 2013 |
Tyrosine supplementation for phenylketonuria.
Topics: Dietary Supplements; Humans; Intelligence; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Randomized Controlled Trials as Topic; Tyrosine | 2013 |
Advances in the nutritional and pharmacological management of phenylketonuria.
Topics: Amino Acids; Biopterins; Bone and Bones; Caseins; Dietary Supplements; Humans; Milk Proteins; Mutation; Peptide Fragments; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Randomized Controlled Trials as Topic; Tyrosine; Whey Proteins | 2014 |
Recommendations for the nutrition management of phenylalanine hydroxylase deficiency.
Topics: Evidence-Based Medicine; Female; Humans; Patient Compliance; Phenylalanine; Phenylketonurias; Practice Guidelines as Topic; Pregnancy; Tyrosine | 2014 |
Epidithiodioxopiperazines. occurrence, synthesis and biogenesis.
Topics: Alkaloids; Biological Products; Fungi; Molecular Structure; Phenylalanine; Piperazines; Stereoisomerism; Tyrosine | 2014 |
Tyrosine, phenylalanine, and tryptophan in gastroesophageal malignancy: a systematic review.
Topics: Esophageal Neoplasms; Humans; Phenylalanine; Stomach Neoplasms; Tryptophan; Tyrosine | 2015 |
Heterologous production of curcuminoids.
Topics: Biological Availability; Biosynthetic Pathways; Carboxylic Acids; Curcuma; Curcumin; Escherichia coli; Phenylalanine; Polyketides; Tyrosine | 2015 |
Old treatments for new insights and strategies: proposed management in adults and children with alkaptonuria.
Topics: Adult; Age Factors; Alkaptonuria; Antioxidants; Child; Cyclohexanones; Humans; Nitrobenzoates; Ochronosis; Phenylalanine; Tyrosine | 2015 |
Biotechnological production of aromatic compounds of the extended shikimate pathway from renewable biomass.
Topics: Amino Acids, Aromatic; Benzaldehydes; Biomass; Biotechnology; Corynebacterium glutamicum; Escherichia coli; Lignin; Metabolic Engineering; Metabolic Networks and Pathways; Organic Chemicals; Parabens; Phenylalanine; Pseudomonas putida; Saccharomyces cerevisiae; Shikimic Acid; Tryptophan; Tyrosine | 2017 |
Pathway engineering for the production of heterologous aromatic chemicals and their derivatives in Saccharomyces cerevisiae: bioconversion from glucose.
Topics: Biotransformation; Chorismic Acid; Fermentation; Glucose; Hydrocarbons, Aromatic; Industrial Microbiology; Metabolic Engineering; Metabolic Networks and Pathways; Phenylalanine; Saccharomyces cerevisiae; Shikimic Acid; Tyrosine | 2017 |
Neurological and Neuropsychological Problems in Tyrosinemia Type I Patients.
Topics: Cyclohexanones; Humans; Nervous System Diseases; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias | 2017 |
Dietary Considerations in Tyrosinemia Type I.
Topics: Cyclohexanones; Diet; Humans; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias | 2017 |
Optimising amino acid absorption: essential to improve nitrogen balance and metabolic control in phenylketonuria.
Topics: Amino Acids; Circadian Rhythm; Diet; Dietary Proteins; Dietary Supplements; Humans; Intestinal Absorption; Nitrogen; Phenylalanine; Phenylketonurias; Tyrosine | 2019 |
The Use of Glycomacropeptide in Patients with Phenylketonuria: A Systematic Review and Meta-Analysis.
Topics: Amino Acids; Caseins; Diet, Protein-Restricted; Dietary Supplements; Humans; Peptide Fragments; Phenylalanine; Phenylketonurias; Tyrosine | 2018 |
Metabolic engineering of microorganisms for production of aromatic compounds.
Topics: Amino Acids, Aromatic; Bacteria; Biomass; Industrial Microbiology; Metabolic Engineering; Organic Chemicals; Phenylalanine; Shikimic Acid; Tryptophan; Tyrosine | 2019 |
Aromatic Amino Acids: A Complex Network Ripe for Future Exploration.
Topics: Amino Acids, Aromatic; Metabolic Networks and Pathways; Phenylalanine; Plants; Tyrosine | 2020 |
PKU dietary handbook to accompany PKU guidelines.
Topics: Diet; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 2020 |
Accessing p-Hydroxycinnamic Acids: Chemical Synthesis, Biomass Recovery, or Engineered Microbial Production?
Topics: Benzaldehydes; Biomass; Coumaric Acids; Escherichia coli; Microwaves; Molecular Structure; Phenylalanine; Plant Extracts; Plants; Saccharomyces cerevisiae; Tyrosine | 2021 |
Tyrosine supplementation for phenylketonuria.
Topics: Dietary Supplements; Humans; Intelligence; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Placebos; Randomized Controlled Trials as Topic; Tyrosine | 2021 |
Efficacy of Phenylalanine- and Tyrosine-Restricted Diet in Alkaptonuria Patients on Nitisinone Treatment: Case Series and Review of Literature.
Topics: Adult; Alkaptonuria; Cyclohexanones; Diet; Dietary Proteins; Female; Humans; Male; Middle Aged; Nitrobenzoates; Phenylalanine; Tyrosine | 2022 |
A Review of Sensors and Biosensors Modified with Conducting Polymers and Molecularly Imprinted Polymers Used in Electrochemical Detection of Amino Acids: Phenylalanine, Tyrosine, and Tryptophan.
Topics: Amino Acids; Biosensing Techniques; Electrochemical Techniques; Molecular Imprinting; Molecularly Imprinted Polymers; Phenylalanine; Polymers; Tryptophan; Tyrosine | 2022 |
Phenylketonuria oxidative stress and energy dysregulation: Emerging pathophysiological elements provide interventional opportunity.
Topics: Adult; Glutathione Disulfide; Glutathione Reductase; Humans; Oxidative Stress; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pyruvates; Tyrosine | 2022 |
3-Deoxy-D-arabino-heptulosonate 7-phosphate synthase as the gatekeeper of plant aromatic natural product biosynthesis.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Biological Products; Phenylalanine; Phosphates; Tyrosine | 2022 |
Periodontal disease metabolomics signatures from different biofluids: a systematic review.
Topics: Alanine; Butyrates; Formates; gamma-Aminobutyric Acid; Humans; Lactates; Metabolomics; Mouthwashes; Periodontal Diseases; Periodontitis; Phenylalanine; Propionates; Tryptophan; Tyrosine; Valine | 2022 |
NMR Studies of Aromatic Ring Flips to Probe Conformational Fluctuations in Proteins.
Topics: Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Phenylalanine; Proteins; Tyrosine | 2023 |
A fast survey on recent developments in designing colorimetric and fluorescent sensors for the selective detection of essential amino acids.
Topics: Amino Acids; Amino Acids, Essential; Arginine; Colorimetry; Phenylalanine; Tyrosine | 2023 |
137 trial(s) available for phenylalanine and tyrosine
| Article | Year |
|---|---|
Dialysis procedures in acute liver coma.
Topics: Acute Disease; Adult; Amino Acids; Bilirubin; Clinical Trials as Topic; Electrolytes; Female; Glucose; Hepatic Encephalopathy; Humans; Male; Phenylalanine; Prothrombin Time; Renal Dialysis; Tyrosine | 1976 |
Use of aspartame by apparently healthy children and adolescents.
Topics: Acne Vulgaris; Adolescent; Adult; Aspartame; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Dipeptides; Female; Humans; Male; Methanol; Middle Aged; Phenylalanine; Phenylpyruvic Acids; Sucrose; Tyrosine; Visual Acuity | 1976 |
Phenylalanine metabolism in uremic and normal man.
Topics: Acetates; Adult; Carbon Dioxide; Clinical Trials as Topic; Humans; Hydroxybenzoates; Lactates; Male; Mandelic Acids; Middle Aged; Phenylalanine; Phenylpyruvic Acids; Renal Dialysis; Tyrosine; Uremia | 1978 |
Use of aspartame in phenylketonuric heteroxygous adults.
Topics: Adult; Aspartame; Clinical Trials as Topic; Dipeptides; Female; Heterozygote; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Placebos; Tyrosine | 1976 |
Milk protein quantity and quality in low-birth-weight infants. IV. Effects on tyrosine and phenylalanine in plasma and urine.
Topics: Animals; Cattle; Humans; Infant Nutritional Physiological Phenomena; Infant, Low Birth Weight; Infant, Newborn; Milk Proteins; Nutritional Requirements; Phenylalanine; Tyrosine | 1977 |
Administration of aspartame in non-insulin-dependent diabetics.
Topics: Adult; Aged; Aspartame; Blood Glucose; Diabetes Mellitus; Dipeptides; Female; Humans; Male; Middle Aged; Phenylalanine; Placebos; Tyrosine | 1976 |
Effect of branched-chain amino acid supplementation on the exercise-induced change in aromatic amino acid concentration in human muscle.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Diet; Exercise; Humans; Muscles; Phenylalanine; Running; Tyrosine | 1992 |
Effect of dietary aspartame on plasma concentrations of phenylalanine and tyrosine in normal and homozygous phenylketonuric patients.
Topics: Adolescent; Adult; Aspartame; Body Weight; Child; Female; Homozygote; Humans; Male; Phenylalanine; Phenylketonurias; Sweetening Agents; Tyrosine | 1992 |
Bioavailability of phenylalanine and aspartate from aspartame (20 mg/kg) in capsules and solution.
Topics: Adolescent; Adult; Amino Acids; Aspartame; Aspartic Acid; Biological Availability; Capsules; Female; Humans; Male; Osmolar Concentration; Phenylalanine; Random Allocation; Solutions; Tyrosine | 1990 |
Increased vigilance and dopamine synthesis by large doses of tyrosine or phenylalanine restriction in phenylketonuria.
Topics: Adolescent; Adult; Arousal; Clinical Trials as Topic; Dopamine; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylalanine; Phenylketonurias; Reaction Time; Tyrosine | 1987 |
Effect of aspartame on plasma amino acid profiles of diabetic patients with chronic renal failure.
Topics: Amino Acids; Aspartame; Diabetic Nephropathies; Dipeptides; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine | 1989 |
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1987 |
Short-term changes in energy intake and serum insulin, neutral amino acids, and urinary catecholamine excretion in women.
Topics: Adult; Amino Acids; Blood Glucose; Dopamine; Energy Intake; Fasting; Female; Humans; Insulin; Leucine; Norepinephrine; Phenylalanine; Tryptophan; Tyrosine; Valine | 1988 |
An open trial of L-tyrosine in the treatment of attention deficit disorder, residual type.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Female; Humans; Levodopa; Male; Middle Aged; Phenylalanine; Psychiatric Status Rating Scales; Tyrosine | 1987 |
Repeated ingestion of aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults.
Topics: Adult; Amino Acids; Aspartame; Beverages; Biological Transport; Brain; Dietary Proteins; Dipeptides; Female; Humans; Male; Phenylalanine; Tyrosine | 1988 |
Plasma amino acid concentrations in normal adults administered aspartame in capsules or solution: lack of bioequivalence.
Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Biological Availability; Capsules; Dipeptides; Female; Humans; Kinetics; Male; Phenylalanine; Solutions; Tyrosine | 1987 |
Biochemical and neuropsychological effects of elevated plasma phenylalanine in patients with treated phenylketonuria. A model for the study of phenylalanine and brain function in man.
Topics: Adolescent; Adult; Biological Transport; Brain; Child; Clinical Trials as Topic; Dopamine; Female; Humans; Kidney Tubules; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Serotonin; Tryptophan; Tyrosine | 1985 |
Amino acid precursors for the treatment of attention deficit disorder, residual type.
Topics: Adult; Attention Deficit Disorder with Hyperactivity; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Phenylalanine; Tyrosine | 1985 |
Phenylalanine and UVA light for the treatment of vitiligo.
Topics: Adolescent; Adult; Clinical Trials as Topic; Female; Humans; Kinetics; Male; Middle Aged; Phenylalanine; Sunlight; Tyrosine; Ultraviolet Therapy; Vitiligo | 1985 |
[Intravenous phenylalanine loading test in normal subjects and the parents of phenylketonuretics].
Topics: Adult; Clinical Trials as Topic; Female; Heterozygote; Humans; Infant; Infant, Newborn; Injections, Intravenous; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
The serotonin-catecholamine-dream bicycle: a clinical study.
Topics: 5-Hydroxytryptophan; Aged; Brain; Brain Chemistry; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Electroencephalography; Female; Fenclonine; Humans; Male; Mental Disorders; Middle Aged; Monoamine Oxidase Inhibitors; Phenylalanine; Serotonin; Sleep; Sleep, REM; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 1972 |
[Fundamental study on the treatment of retinitis pigmentosa].
Topics: Adolescent; Adult; Aged; Amino Acids; Animals; Antidotes; Anura; Clinical Trials as Topic; Dihydroxyphenylalanine; Electroretinography; Female; Hormones; Humans; In Vitro Techniques; Light; Lipids; Male; Melanocyte-Stimulating Hormones; Middle Aged; Peroxides; Phenylalanine; Rats; Regeneration; Reserpine; Retinal Degeneration; Retinal Pigments; Retinitis Pigmentosa; Tetrabenazine; Tyrosine; Vasodilator Agents; Vitamins | 1969 |
Management of transient hyperphenylalaninemia and tyrosinemia in low birth weight Negro infants fed high protein diets.
Topics: Ascorbic Acid; Birth Weight; Black People; Clinical Trials as Topic; Dietary Proteins; Humans; Infant, Newborn; Infant, Premature; Injections, Intramuscular; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1971 |
Protein intake and plasma amino-acids of infants of low birth weight.
Topics: Amino Acids; Animals; Birth Weight; Cystathionine; Dietary Proteins; Enzymes; Humans; Infant; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Methionine; Milk; Milk, Human; Phenylalanine; Stress, Physiological; Tyrosine | 1971 |
Daily rhythms in the concentrations of various amino acids in human plasma.
Topics: Adolescent; Adult; Alanine; Amino Acids; Circadian Rhythm; Cysteine; Dietary Proteins; Glutamates; Glycine; Humans; Isoleucine; Male; Methionine; Phenylalanine; Tryptophan; Tyrosine | 1968 |
Inhibition of serotonin synthesis by para-chlorophenylalanine in patients with the carcinoid syndrome.
Topics: Adult; Aged; Amino Acids; Female; Humans; Hydroxyindoleacetic Acid; Ileum; Indoles; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Placebos; Serotonin; Serotonin Antagonists; Tyrosine | 1967 |
L-phenylalanine and UVA irradiation in the treatment of vitiligo.
Topics: Administration, Oral; Adolescent; Adult; Combined Modality Therapy; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Middle Aged; Phenylalanine; Tyrosine; Ultraviolet Therapy; Vitiligo | 1994 |
Effect of high-dose tyrosine supplementation on brain function in adults with phenylketonuria.
Topics: Adolescent; Adult; Brain; Cognition Disorders; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials, Visual; Female; Humans; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Placebos; Psychological Tests; Reaction Time; Tyrosine | 1995 |
Acute changes in leucine and phenylalanine kinetics produced by parenteral nutrition in premature infants.
Topics: Amino Acids; Blood Glucose; Calorimetry; Enteral Nutrition; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Insulin; Kinetics; Leucine; Male; Phenylalanine; Time Factors; Tyrosine | 1997 |
Glutamine and other amino acid losses during continuous venovenous hemodiafiltration.
Topics: Acute Kidney Injury; Adult; Aged; Amino Acids; Female; Glutamine; Hemodiafiltration; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Multiple Organ Failure; Parenteral Nutrition, Total; Phenylalanine; Reference Standards; Tyrosine; Valine | 1997 |
Elevated serum prolactin concentrations in phenylketonuric patients on a 'loose diet'.
Topics: Adolescent; Diet; Dopamine; Epinephrine; Evaluation Studies as Topic; Female; Humans; Male; Norepinephrine; Phenylalanine; Phenylketonurias; Prolactin; Statistics, Nonparametric; Tyrosine | 1998 |
Randomised controlled trial of tyrosine supplementation on neuropsychological performance in phenylketonuria.
Topics: Administration, Oral; Adolescent; Adult; Alanine; Child; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Treatment Failure; Tyrosine | 1998 |
Phenylalanine and tyrosine metabolism in neonates receiving parenteral nutrition differing in pattern of amino acids.
Topics: Amino Acids; Carbon Isotopes; Deuterium; Female; Humans; Hydroxylation; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Kinetics; Male; Nutritional Requirements; Oxidation-Reduction; Parenteral Nutrition, Total; Phenylalanine; Tyrosine | 1998 |
Attenuation of some subjective effects of amphetamine following tyrosine depletion.
Topics: Adult; Appetite; Arousal; Dextroamphetamine; Dopamine; Double-Blind Method; Female; Humans; Hunger; Male; Middle Aged; Norepinephrine; Pain Measurement; Phenylalanine; Tyrosine | 1999 |
The pattern of intracellular free amino acids in granulocytes from hemodialysis patients change to an oral protein supplement (granulocyte amino acids after protein in HD patients).
Topics: Adult; Aged; Amino Acids; Anthropometry; Blood Proteins; Cross-Over Studies; Dietary Proteins; Dietary Supplements; Double-Blind Method; Electric Impedance; Female; Glycine; Granulocytes; Humans; Isoleucine; Male; Middle Aged; Nitrogen; Phenylalanine; Placebos; Renal Dialysis; Somatomedins; Threonine; Tyrosine; Valine | 1999 |
A comparison of the effects of acute tryptophan depletion and acute phenylalanine/tyrosine depletion in healthy women.
Topics: Adult; Affect; Anxiety; Catecholamines; Double-Blind Method; Female; Heart Rate; Humans; Phenylalanine; Stress, Psychological; Tryptophan; Tyrosine | 1999 |
Effect of tyrosine intake on the rate of phenylalanine hydroxylation in adult males.
Topics: Adult; Dose-Response Relationship, Drug; Humans; Hydroxylation; Male; Phenylalanine; Regression Analysis; Tyrosine | 2000 |
Acute tyrosine depletion and alcohol ingestion in healthy women.
Topics: Adult; Alcohol Drinking; Analysis of Variance; Double-Blind Method; Female; Humans; Phenylalanine; Self Administration; Synaptic Transmission; Tryptophan; Tyrosine | 2000 |
Nadolol inhibits reactive oxygen species generation by leukocytes and linoleic acid oxidation.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Chromatography, High Pressure Liquid; Female; Humans; Leukocytes, Mononuclear; Linoleic Acid; Male; Nadolol; Neutrophils; Oxidation-Reduction; Phenylalanine; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tyrosine | 2000 |
The effect of graded intake of glycyl-L-tyrosine on phenylalanine and tyrosine metabolism in parenterally fed neonates with an estimation of tyrosine requirement.
Topics: Amino Acids; Dipeptides; Humans; Infant, Newborn; Parenteral Nutrition; Phenylalanine; Tyrosine | 2001 |
Tyrosine requirement of healthy men receiving a fixed phenylalanine intake determined by using indicator amino acid oxidation.
Topics: Adult; Amino Acids; Breath Tests; Carbon Dioxide; Carbon Isotopes; Humans; Linear Models; Lysine; Male; Nitrogen; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Safety; Time Factors; Tyrosine | 2001 |
Response to pentagastrin after acute phenylalanine and tyrosine depletion in healthy men: a pilot study.
Topics: Adult; Anxiety; Arousal; Cross-Over Studies; Double-Blind Method; Humans; Male; Panic; Pentagastrin; Phenylalanine; Pilot Projects; Tyrosine | 2001 |
BCAA intake affects protein metabolism in muscle after but not during exercise in humans.
Topics: Administration, Oral; Adult; Arteries; Biopsy; Blood Flow Velocity; Exercise Test; Glutamine; Glycogen; Growth Hormone; Heart Rate; Humans; Insulin; Isoleucine; Lactic Acid; Leucine; Male; Muscle, Skeletal; Norepinephrine; Oxygen Consumption; Phenylalanine; Physical Exertion; Proteins; Pulmonary Gas Exchange; Tyrosine; Valine | 2001 |
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine | 2001 |
Results of a phase I trial evaluating a liver support device utilizing albumin dialysis.
Topics: Adolescent; Adult; Ammonia; Bilirubin; Blood Coagulation; Hemodiafiltration; Hepatic Encephalopathy; Humans; Isoleucine; Kidney; Leucine; Liver; Liver Failure, Acute; Middle Aged; Phenylalanine; Serum Albumin; Treatment Outcome; Tyrosine; Valine | 2001 |
Enhancement of noradrenergic neural transmission: an effective therapy of myasthenia gravis: a report on 52 consecutive patients.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Aged; Benzhydryl Compounds; Buspirone; Desipramine; Drug Therapy, Combination; Electromyography; Epinephrine; Female; Humans; Hydroxamic Acids; Male; Middle Aged; Modafinil; Myasthenia Gravis; Neuroprotective Agents; Neurotransmitter Agents; Norepinephrine; Phenylalanine; Platelet Aggregation; Propranolol; Serotonin; Serotonin Receptor Agonists; Sympathetic Nervous System; Tyrosine | 2000 |
Evaluation of 13C-phenylalanine and 13C-tyrosine breath tests for the measurement of hepatocyte functional capacity in patients with liver cirrhosis.
Topics: Adult; Aged; Breath Tests; Carbon Dioxide; Female; Hepatocytes; Humans; Liver Cirrhosis; Liver Function Tests; Male; Middle Aged; Phenylalanine; Tyrosine | 2001 |
A dose-finding study on the effects of branch chain amino acids on surrogate markers of brain dopamine function.
Topics: Adult; Amino Acids, Branched-Chain; Cross-Over Studies; Dopamine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Pattern Recognition, Visual; Phenylalanine; Prolactin; Recognition, Psychology; Space Perception; Time Factors; Tryptophan; Tyrosine | 2002 |
Behavioural effects of acute phenylalanine and tyrosine depletion in healthy male volunteers.
Topics: Adult; Affect; Attention; Behavior; Cross-Over Studies; Diet; Double-Blind Method; Humans; Male; Memory; Phenylalanine; Psychiatric Status Rating Scales; Psychomotor Performance; Tyrosine | 2002 |
The effect of long-term pharmacological antilipolysis on substrate metabolism in growth hormone (GH)-substituted GH-deficient adults.
Topics: Adult; Body Composition; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Growth Hormone; Hormones; Human Growth Hormone; Humans; Hypolipidemic Agents; Lipoprotein Lipase; Lipoproteins; Male; Metabolism, Inborn Errors; Middle Aged; Phenylalanine; Pyrazines; Tyrosine | 2002 |
Effects of serotonin and catecholamine depletion on interleukin-6 activation and mood in human volunteers.
Topics: Adult; Affect; Catecholamines; Cross-Over Studies; Female; Humans; Interleukin-6; Phenylalanine; Serotonin; Tryptophan; Tyrosine | 2002 |
Effects of lowering circulating free fatty acid levels on protein metabolism in adult growth hormone deficient patients.
Topics: Adult; Area Under Curve; Blood Glucose; Dwarfism, Pituitary; Fatty Acids, Nonesterified; Female; Forearm; Growth Hormone; Humans; Hypolipidemic Agents; Lipolysis; Male; Middle Aged; Phenylalanine; Proteins; Pyrazines; Tyrosine; Urea | 2002 |
Phenylalanine kinetics in healthy volunteers and liver cirrhotics: implications for the phenylalanine breath test.
Topics: Adult; Aged; Body Fluid Compartments; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Carbon Isotopes; Female; Gas Chromatography-Mass Spectrometry; Humans; Liver Cirrhosis, Alcoholic; Male; Mass Spectrometry; Middle Aged; Oxidation-Reduction; Phenylalanine; Predictive Value of Tests; Reference Values; Reproducibility of Results; Tyrosine | 2002 |
Brain monoamines and early visual information-processing speed.
Topics: Adult; Amino Acids; Biogenic Monoamines; Brain Chemistry; Cross-Over Studies; Discrimination, Psychological; Double-Blind Method; Female; Humans; Phenylalanine; Serotonin; Tryptophan; Tyrosine; Visual Perception | 2002 |
Effect of parenteral glutamine supplementation on plasma amino acid concentrations in extremely low-birth-weight infants.
Topics: Amino Acids; Ammonia; Female; Glutamic Acid; Glutamine; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Very Low Birth Weight; Male; Nutritional Requirements; Parenteral Nutrition; Phenylalanine; Safety; Tyrosine | 2003 |
The phenylalanine loading test in the differential diagnosis of dystonia.
Topics: Administration, Oral; Adult; Diagnosis, Differential; Dystonia; Female; Humans; Levodopa; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Time Factors; Tyrosine | 2003 |
Are tablets a practical source of protein substitute in phenylketonuria?
Topics: Adolescent; Adult; Amino Acids; Beverages; Child; Cross-Over Studies; Dietary Supplements; Female; Humans; Male; Patient Compliance; Phenylalanine; Phenylketonurias; Tablets; Tyrosine | 2003 |
Large neutral amino acid therapy and phenylketonuria: a promising approach to treatment.
Topics: Adult; Amino Acids; Brain; Diet; Dose-Response Relationship, Drug; Female; Humans; Magnetic Resonance Spectroscopy; Male; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 2003 |
Evaluation of nutritional status and pathophysiology of growth retardation in patients with phenylketonuria.
Topics: Aging; Anthropometry; Body Composition; Body Height; Body Weight; Child; Child, Preschool; Chromatography, Gas; Cross-Sectional Studies; Diet; Erythrocytes; Female; Growth Disorders; Hormones; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Nutritional Status; Phenylalanine; Phenylketonurias; Thyroid Hormones; Trace Elements; Tyrosine | 2003 |
The decisive role of free fatty acids for protein conservation during fasting in humans with and without growth hormone.
Topics: Adult; Amino Acids; Fasting; Fatty Acids, Nonesterified; Growth Hormone; Heparin; Hormone Antagonists; Human Growth Hormone; Humans; Hypolipidemic Agents; Lipolysis; Male; Microdialysis; Muscle, Skeletal; Phenylalanine; Proteins; Pyrazines; Somatostatin; Triglycerides; Tyrosine; Urea | 2003 |
Acute exposure to GH during exercise stimulates the turnover of free fatty acids in GH-deficient men.
Topics: Adolescent; Adult; Blood Glucose; Body Mass Index; C-Peptide; Calorimetry, Indirect; Energy Metabolism; Exercise; Fatty Acids, Nonesterified; Human Growth Hormone; Humans; Insulin; Male; Middle Aged; Muscle Proteins; Palmitates; Phenylalanine; Tyrosine | 2004 |
Selective effects of simultaneous monoamine depletion on mood and emotional responsiveness.
Topics: Adolescent; Adult; Affect; Amino Acids; Biogenic Monoamines; Cross-Over Studies; Double-Blind Method; Expressed Emotion; Female; Humans; Phenylalanine; Psychometrics; Reaction Time; Tryptophan; Tyrosine | 2004 |
Simultaneous depletion of tryptophan, tyrosine and phenylalanine as an experimental method to probe brain monoamine function in humans.
Topics: Adolescent; Adult; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Phenylalanine; Tryptophan; Tyrosine | 2004 |
A preliminary report on dopamine system reactivity in PKU: acute effects of haloperidol on neuropsychological, physiological, and neuroendocrine functions.
Topics: Adult; Blood Pressure; Cognition; Dopamine; Dopamine Antagonists; Double-Blind Method; Female; Haloperidol; Heart Rate; Humans; Male; Memory, Short-Term; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Prolactin; Task Performance and Analysis; Tyrosine | 2004 |
Simultaneous depletion of serotonin and catecholamines impairs sustained attention in healthy female subjects without affecting learning and memory.
Topics: Adolescent; Adult; Affect; Attention; Brain; Catecholamines; Cognition; Double-Blind Method; Female; Humans; Learning; Memory; Phenylalanine; Reaction Time; Serotonin; Tryptophan; Tyrosine | 2004 |
Selective effects of acute serotonin and catecholamine depletion on memory in healthy women.
Topics: Adult; Affect; Attention; Brain; Catecholamines; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Memory; Phenylalanine; Serotonin; Tryptophan; Tyrosine | 2004 |
Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations.
Topics: Adult; Aged; Amino Acids; Biopterins; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neopterin; Phenylalanine; Pilot Projects; Polyethylene Glycols; Pteridines; Randomized Controlled Trials as Topic; Recombinant Proteins; Time Factors; Tryptophan; Tyrosine | 2004 |
Tyrosine depletion does not cause depressive relapse in antidepressant-treated patients.
Topics: Adult; Amino Acids, Neutral; Antidepressive Agents, Tricyclic; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Female; Humans; Middle Aged; Phenylalanine; Prolactin; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Tryptophan; Tyrosine | 2004 |
Impairment of phenylalanine conversion to tyrosine in end-stage renal disease causing tyrosine deficiency.
Topics: Adult; Aged; Deuterium; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Kidney Failure, Chronic; Middle Aged; Nitrogen Isotopes; Phenylalanine; Tyrosine | 2004 |
Phenylalanine kinetics differ between formula-fed and human milk-fed preterm infants.
Topics: Female; Half-Life; Humans; Infant; Infant Food; Infant, Newborn; Male; Milk, Human; Phenylalanine; Tyrosine | 2004 |
Combined ingestion of protein and free leucine with carbohydrate increases postexercise muscle protein synthesis in vivo in male subjects.
Topics: Adult; Dietary Carbohydrates; Dietary Proteins; Double-Blind Method; Exercise; Humans; Insulin; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Tyrosine | 2005 |
The subjective and cognitive effects of acute phenylalanine and tyrosine depletion in patients recovered from depression.
Topics: Adult; Amino Acids, Neutral; Brain; Cognition Disorders; Cross-Over Studies; Decision Making; Depressive Disorder; Dopamine; Double-Blind Method; Female; Food, Formulated; Gambling; Humans; Judgment; Male; Middle Aged; Neuropsychological Tests; Phenylalanine; Recovery of Function; Reward; Tyrosine | 2005 |
Lack of effect of tyrosine depletion on mood in recovered depressed women.
Topics: Adult; Affect; Amino Acids, Neutral; Brain; Cognition; Cross-Over Studies; Depressive Disorder; Dopamine; Double-Blind Method; Female; Food, Formulated; Humans; Middle Aged; Neuropsychological Tests; Phenylalanine; Prolactin; Recovery of Function; Tyrosine; Up-Regulation | 2005 |
Combined D1/D2 receptor stimulation under conditions of dopamine depletion impairs spatial working memory performance in humans.
Topics: Adolescent; Adult; Amino Acids; Domperidone; Dopamine; Double-Blind Method; Flicker Fusion; Humans; Male; Memory, Short-Term; Orientation; Pattern Recognition, Visual; Pergolide; Phenylalanine; Prefrontal Cortex; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Tyrosine | 2005 |
Cognitive functions in classic phenylketonuria and mild hyperphenylalaninaemia: experience in a paediatric population.
Topics: Adolescent; Adult; Analysis of Variance; Attention; Case-Control Studies; Child; Child, Preschool; Chromatography, Ion Exchange; Cognition; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Intelligence; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Problem Solving; Psychomotor Performance; Spatial Behavior; Statistics, Nonparametric; Tyrosine; Verbal Behavior; Visual Perception | 2005 |
Response of patients with phenylketonuria in the US to tetrahydrobiopterin.
Topics: Administration, Oral; Adolescent; Adult; Biopterins; Child; Child, Preschool; Diet, Protein-Restricted; Dose-Response Relationship, Drug; Humans; Infant; Los Angeles; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Texas; Tyrosine | 2005 |
The effects of acute tyrosine and phenylalanine depletion on spatial working memory and planning in healthy volunteers are predicted by changes in striatal dopamine levels.
Topics: Adult; Carbon Isotopes; Corpus Striatum; Cross-Over Studies; Diet, Protein-Restricted; Dopamine; Dopamine Antagonists; Double-Blind Method; Female; Humans; Male; Memory, Short-Term; Neuropsychological Tests; Pain Measurement; Phenylalanine; Positron-Emission Tomography; Problem Solving; Raclopride; Reaction Time; Space Perception; Tyrosine | 2005 |
Aromatic amino acid requirements in healthy men measured by indicator amino acid oxidation.
Topics: Adult; Amino Acids, Aromatic; Breath Tests; Canada; Carbon Dioxide; Carbon Isotopes; Cross-Over Studies; Dose-Response Relationship, Drug; Humans; Linear Models; Lysine; Male; Nutrition Policy; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Tyrosine | 2006 |
Cocaine craving, euphoria, and self-administration: a preliminary study of the effect of catecholamine precursor depletion.
Topics: Adult; Catecholamines; Circadian Rhythm; Cocaine; Cocaine-Related Disorders; Diet, Protein-Restricted; Dopamine Agents; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Euphoria; Humans; Levodopa; Male; Phenylalanine; Self Administration; Time Factors; Tyrosine | 2005 |
Lack of effect of acute dopamine precursor depletion in nicotine-dependent smokers.
Topics: Adult; Diet, Protein-Restricted; Dopamine; Dopamine Agents; Humans; Levodopa; Male; Pain Measurement; Phenylalanine; Self Administration; Surveys and Questionnaires; Time Factors; Tobacco Use Disorder; Tyrosine | 2006 |
'Ready to drink' protein substitute is easier is for people with phenylketonuria.
Topics: Adolescent; Adult; Beverages; Child; Cross-Over Studies; Diet; Dietary Supplements; Female; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Proteins; Tyrosine | 2006 |
Brain dopamine and kinematics of graphomotor functions.
Topics: Adult; Aged; Antiparkinson Agents; Biomechanical Phenomena; Brain; Computer Graphics; Cross-Over Studies; Dopamine; Dopamine Agonists; Double-Blind Method; Echoencephalography; Female; Handwriting; Humans; Male; Middle Aged; Parkinson Disease; Phenylalanine; Reaction Time; Reference Values; Signal Processing, Computer-Assisted; Substantia Nigra; Synaptic Transmission; Tyrosine | 2006 |
Co-ingestion of protein and leucine stimulates muscle protein synthesis rates to the same extent in young and elderly lean men.
Topics: Activities of Daily Living; Adult; Aged; Aging; Carbon Isotopes; Cross-Over Studies; Dietary Carbohydrates; Dietary Proteins; Double-Blind Method; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Tyrosine | 2006 |
Evidence that phenylalanine may not provide the full needs for aromatic amino acids in children.
Topics: Amino Acids, Aromatic; Carbon Dioxide; Carbon Isotopes; Child; Child Nutritional Physiological Phenomena; Humans; Hydroxylation; Lysine; Nutritional Requirements; Phenylalanine; Tyrosine | 2007 |
Mood-elevating effects of d-amphetamine and incentive salience: the effect of acute dopamine precursor depletion.
Topics: Adult; Affect; Attention; Carbidopa; Central Nervous System Stimulants; Dextroamphetamine; Dopamine; Double-Blind Method; Drug Combinations; Humans; Levodopa; Male; Motivation; Neuropsychological Tests; Pain Measurement; Phenylalanine; Reaction Time; Tyrosine | 2007 |
The effects of large neutral amino acid supplements in PKU: an MRS and neuropsychological study.
Topics: Adult; Amino Acids, Neutral; Blood-Brain Barrier; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Female; Humans; Magnetic Resonance Spectroscopy; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Prospective Studies; Tyrosine | 2007 |
Protein metabolism in Turner syndrome and the impact of hormone replacement therapy.
Topics: Adult; Body Composition; Calorimetry, Indirect; Cross-Over Studies; Deuterium; Energy Metabolism; Estrogens; Female; Hormone Replacement Therapy; Humans; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; Progesterone; Proteins; Turner Syndrome; Tyrosine; Young Adult | 2007 |
Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole-body protein and glucose kinetics.
Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Calorimetry; Carbohydrates; Colonic Diseases; Female; Glucose; Humans; Infusions, Intravenous; Male; Middle Aged; Phenylalanine; Postoperative Period; Preoperative Care; Rectal Diseases; Tyrosine | 2007 |
In vivo regulation of phenylalanine hydroxylation to tyrosine, studied using enrichment in apoB-100.
Topics: Adult; Apolipoprotein B-100; Diet; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Kinetics; Lysine; Male; Oxidation-Reduction; Phenylalanine; Tyrosine | 2008 |
Effects of selective and combined serotonin and dopamine depletion on the loudness dependence of the auditory evoked potential (LDAEP) in humans.
Topics: Acoustic Stimulation; Adult; Cross-Over Studies; Dopamine; Double-Blind Method; Electroencephalography; Electromyography; Evoked Potentials, Auditory; Humans; Loudness Perception; Male; Phenylalanine; Serotonin; Tryptophan; Tyrosine | 2008 |
The role of dopamine in alcohol self-administration in humans: individual differences.
Topics: Adult; Alcohol Drinking; Amino Acids; Analysis of Variance; Dopamine; Dopamine Agents; Double-Blind Method; Ethanol; Heart Rate; Humans; Individuality; Levodopa; Male; Phenylalanine; Self Administration; Tyrosine | 2008 |
Protein coingestion stimulates muscle protein synthesis during resistance-type exercise.
Topics: Adult; Amino Acids, Branched-Chain; Biopsy; Dietary Carbohydrates; Dietary Proteins; Humans; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Physical Fitness; Protein Biosynthesis; Random Allocation; Tyrosine | 2008 |
Effects of sex steroids on the neurotransmitter-specific aromatic amino acids phenylalanine, tyrosine, and tryptophan in transsexual subjects.
Topics: Adolescent; Adult; Amino Acids, Aromatic; Cyproterone Acetate; Ethinyl Estradiol; Female; Gonadal Steroid Hormones; Humans; Male; Models, Biological; Neurotransmitter Agents; Phenylalanine; Substrate Specificity; Synaptic Transmission; Testosterone; Transsexualism; Tryptophan; Tyrosine | 2008 |
Neurometabolic effects of ACTH on free amino compounds in opsoclonus-myoclonus syndrome.
Topics: Adrenocorticotropic Hormone; Alanine; Amino Acids; Analysis of Variance; Child; Child, Preschool; Chromatography, Gas; Corticosterone; Dose-Response Relationship, Drug; Female; Glutamine; Humans; Immunotherapy; Lysine; Male; Mass Spectrometry; Opsoclonus-Myoclonus Syndrome; Ornithine; Phenylalanine; Severity of Illness Index; Taurine; Tyrosine | 2008 |
Striatal dopamine responses to intranasal cocaine self-administration in humans.
Topics: Administration, Intranasal; Basal Ganglia; Cocaine; Dopamine; Female; Humans; Hydrocortisone; Male; Phenylalanine; Positron-Emission Tomography; Putamen; Raclopride; Receptors, Dopamine D2; Self Administration; Tyrosine; Young Adult | 2009 |
Impact of growth hormone receptor blockade on substrate metabolism during fasting in healthy subjects.
Topics: Blood Glucose; Body Mass Index; Cross-Over Studies; Fasting; Fatty Acids, Nonesterified; Glucose Clamp Technique; Growth Hormone; Human Growth Hormone; Humans; Insulin-Like Growth Factor I; Middle Aged; Phenylalanine; Placebos; Receptors, Somatotropin; Reference Values; Single-Blind Method; Tyrosine; Urea; Young Adult | 2009 |
Effects of tyrosine/phenylalanine depletion on electrophysiological correlates of memory in healthy volunteers.
Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Evoked Potentials; Female; Humans; Male; Memory, Short-Term; Mental Recall; Phenylalanine; Placebos; Psychomotor Performance; Tyrosine; Verbal Learning | 2011 |
Acute dopamine and/or serotonin depletion does not modulate mismatch negativity (MMN) in healthy human participants.
Topics: Adult; Contingent Negative Variation; Cross-Over Studies; Dopamine; Double-Blind Method; Electroencephalography; Humans; Male; Neural Pathways; Phenylalanine; Reaction Time; Serotonin; Time Factors; Tryptophan; Tyrosine; Young Adult | 2010 |
Dopamine precursor depletion improves punishment prediction during reversal learning in healthy females but not males.
Topics: Adult; Cross-Over Studies; Dopamine; Double-Blind Method; Female; Humans; Male; Middle Aged; Phenylalanine; Punishment; Reversal Learning; Reward; Sex Factors; Tyrosine; Young Adult | 2010 |
Effects of dietary energy intake and cold exposure on kinetics of plasma phenylalanine, tyrosine and protein synthesis in sheep.
Topics: Animal Feed; Animal Husbandry; Animal Nutritional Physiological Phenomena; Animals; Cold Temperature; Cross-Over Studies; Diet; Female; Male; Phenylalanine; Sheep; Tyrosine | 2010 |
Estrogen treatment impairs cognitive performance after psychosocial stress and monoamine depletion in postmenopausal women.
Topics: Affect; Aged; Aged, 80 and over; Anxiety; Cognition Disorders; Double-Blind Method; Estradiol; Estrogens; Female; Follicle Stimulating Hormone; Humans; Hydrocortisone; Mental Recall; Middle Aged; Neuropsychological Tests; Phenylalanine; Postmenopause; Stress, Psychological; Tryptophan; Tyrosine | 2010 |
Neuropsychological outcome of NTBC-treated patients with tyrosinaemia type 1.
Topics: Adolescent; Belgium; Child; Child, Preschool; Cognition Disorders; Cyclohexanones; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Intelligence; Intelligence Tests; Male; Neuropsychological Tests; Nitrobenzoates; Phenylalanine; Treatment Outcome; Tyrosine; Tyrosinemias | 2011 |
Acute phenylalanine/tyrosine depletion reduces motivation to smoke cigarettes across stages of addiction.
Topics: Adolescent; Adult; Behavior, Addictive; Female; Humans; Male; Motivation; Phenylalanine; Smoking; Smoking Cessation; Time Factors; Tyrosine; Young Adult | 2011 |
Protein requirement of healthy school-age children determined by the indicator amino acid oxidation method.
Topics: Amino Acids; Carbon Dioxide; Carbon Isotopes; Child; Cross-Over Studies; Dietary Carbohydrates; Dietary Proteins; Egg Proteins; Energy Intake; Female; Humans; Isotope Labeling; Male; Nutrition Policy; Nutritional Requirements; Phenylalanine; Tyrosine | 2011 |
Reliance on habits at the expense of goal-directed control following dopamine precursor depletion.
Topics: Adaptation, Psychological; Adult; Amino Acids; Conditioning, Operant; Dopamine; Female; Habits; Humans; Male; Middle Aged; Phenylalanine; Tyrosine | 2012 |
Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men.
Topics: Aged; Aging; Algorithms; Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Digestion; Humans; Insulin; Intestinal Absorption; Kinetics; Male; Milk Proteins; Muscle Proteins; Oxidation-Reduction; Phenylalanine; Postprandial Period; Quadriceps Muscle; Tyrosine; Whey Proteins | 2012 |
Enhanced anabolic response to milk protein sip feeding in elderly subjects with COPD is associated with a reduced splanchnic extraction of multiple amino acids.
Topics: Administration, Intravenous; Administration, Oral; Aged; Amino Acids, Branched-Chain; Body Composition; Body Weight; Humans; Isoleucine; Leucine; Male; Meals; Middle Aged; Milk Proteins; Phenylalanine; Pulmonary Disease, Chronic Obstructive; Tyrosine; Valine; Whey Proteins; Young Adult | 2012 |
Effect of hyperalimentation and insulin-treated hyperglycemia on tyrosine levels in very preterm infants receiving parenteral nutrition.
Topics: Birth Weight; Blood Glucose; Humans; Hyperglycemia; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Insulin; Parenteral Nutrition Solutions; Parenteral Nutrition, Total; Phenylalanine; Tyrosine | 2014 |
Acute oral administration of a tyrosine and phenylalanine-free amino acid mixture reduces exercise capacity in the heat.
Topics: Administration, Oral; Adult; Cross-Over Studies; Double-Blind Method; Exercise Tolerance; Hot Temperature; Humans; Humidity; Male; Phenylalanine; Tyrosine | 2013 |
Minced beef is more rapidly digested and absorbed than beef steak, resulting in greater postprandial protein retention in older men.
Topics: Aged; Animals; Biological Availability; Blood Glucose; Carbon Isotopes; Cattle; Cross-Over Studies; Dietary Proteins; Digestion; Humans; Male; Meat; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Postprandial Period; Surveys and Questionnaires; Tyrosine | 2013 |
Dietary tyrosine/phenylalanine depletion effects on behavioral and brain signatures of human motivational processing.
Topics: Adult; Amino Acids; Analysis of Variance; Brain Mapping; Double-Blind Method; Female; Food, Formulated; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Motivation; Nucleus Accumbens; Oxygen; Phenylalanine; Reaction Time; Reward; Tyrosine; Young Adult | 2014 |
Failure of oral tyrosine supplementation to improve exercise performance in the heat.
Topics: Administration, Oral; Adult; Amino Acids; Beverages; Bicycling; Body Temperature; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Exercise Tolerance; Heart Rate; Hot Temperature; Humans; Male; Phenylalanine; Skin Temperature; Thermosensing; Tyrosine; Young Adult | 2014 |
Adaptive regulation of amino acid metabolism on early parenteral lipid and high-dose amino acid administration in VLBW infants - a randomized, controlled trial.
Topics: Amino Acids; Dietary Fats; Dose-Response Relationship, Drug; Emulsions; Energy Intake; Female; Fish Oils; Glucose; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Keto Acids; Leucine; Male; Olive Oil; Parenteral Nutrition; Phenylalanine; Plant Oils; Soybean Oil; Tyrosine | 2014 |
Effects of a caloric restriction weight loss diet on tryptophan metabolism and inflammatory biomarkers in overweight adults.
Topics: Austria; Biomarkers; Body Mass Index; Caloric Restriction; Diet, Reducing; Female; Humans; Inflammation Mediators; Kynurenine; Leptin; Male; Middle Aged; Mood Disorders; Neopterin; Overweight; Phenylalanine; Risk; Tryptophan; Tyrosine; Weight Loss | 2015 |
Citrulline stimulates muscle protein synthesis in the post-absorptive state in healthy people fed a low-protein diet - A pilot study.
Topics: Adult; Arginine; Blood Glucose; C-Peptide; Citrulline; Cross-Over Studies; Diet, Protein-Restricted; Dietary Proteins; Female; Humans; Insulin; Insulin-Like Growth Factor I; Male; Mitochondrial Proteins; Muscle Proteins; Ornithine; Phenylalanine; Pilot Projects; Protein Biosynthesis; Tyrosine; Young Adult | 2015 |
Fasting increases human skeletal muscle net phenylalanine release and this is associated with decreased mTOR signaling.
Topics: Amino Acids; Analysis of Variance; Blotting, Western; Cross-Over Studies; Energy Metabolism; Fasting; Fatty Acids, Nonesterified; Gas Chromatography-Mass Spectrometry; Glucagon; Humans; Male; Muscle, Skeletal; Phenylalanine; Radioimmunoassay; Signal Transduction; TOR Serine-Threonine Kinases; Tyrosine | 2014 |
Serotonin and dopamine differentially affect appetitive and aversive general Pavlovian-to-instrumental transfer.
Topics: Adult; Appetite; Conditioning, Classical; Cues; Decision Making; Diet; Dopamine; Double-Blind Method; Female; Humans; Male; Motivation; Neurotransmitter Agents; Phenylalanine; Serotonin; Tryptophan; Tyrosine; Young Adult | 2015 |
Dietary protein requirement of female adults >65 years determined by the indicator amino acid oxidation technique is higher than current recommendations.
Topics: Age Factors; Aged; Aged, 80 and over; Amino Acids; Carbon Isotopes; Dietary Proteins; Energy Intake; Energy Metabolism; Female; Fluorine; Humans; Isotope Labeling; Nutritional Physiological Phenomena; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Tyrosine | 2015 |
Age moderates the effect of acute dopamine depletion on passive avoidance learning.
Topics: Adult; Age Factors; Avoidance Learning; Cross-Over Studies; Dopamine; Double-Blind Method; Female; Humans; Male; Phenylalanine; Reaction Time; Tyrosine; Young Adult | 2015 |
Effects of branched-chain amino acids supplementation on both plasma amino acids concentration and muscle energetics changes resulting from muscle damage: A randomized placebo controlled trial.
Topics: Adult; Alanine; Amino Acids, Branched-Chain; Body Mass Index; Body Weight; Dietary Supplements; Double-Blind Method; Exercise; Glycine; Histidine; Humans; Hydrogen-Ion Concentration; Knee; Magnetic Resonance Spectroscopy; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Phosphates; Phosphocreatine; Tyrosine; Young Adult | 2016 |
Amino acid supplementation is anabolic during the acute phase of endotoxin-induced inflammation: A human randomized crossover trial.
Topics: Adaptor Proteins, Signal Transducing; Adult; Amino Acids; Body Mass Index; Cell Cycle Proteins; Cross-Over Studies; Dietary Supplements; Endotoxemia; Endotoxins; Glucose Clamp Technique; Hormones; Humans; Inflammation; Insulin; Interleukin-10; Interleukin-6; Linear Models; Male; Mechanistic Target of Rapamycin Complex 1; Models, Theoretical; Multiprotein Complexes; Muscle, Skeletal; Phenylalanine; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Signal Transduction; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Tyrosine; Urea | 2016 |
Phenylalanine requirements of enterally fed term and preterm neonates.
Topics: Cross-Over Studies; Enteral Nutrition; Female; Gestational Age; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Linear Models; Male; Milk, Human; Nutritional Requirements; Phenylalanine; Term Birth; Tyrosine | 2015 |
Ingestion of Casein in a Milk Matrix Modulates Dietary Protein Digestion and Absorption Kinetics but Does Not Modulate Postprandial Muscle Protein Synthesis in Older Men.
Topics: Aged; Blood Glucose; Caseins; Dairy Products; Dietary Proteins; Healthy Volunteers; Humans; Insulin; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Postprandial Period; Protein Biosynthesis; Tyrosine | 2015 |
Prolonged Adaptation to a Low or High Protein Diet Does Not Modulate Basal Muscle Protein Synthesis Rates - A Substudy.
Topics: Adult; Diet, Protein-Restricted; Dietary Proteins; Fasting; Female; Glucose; Humans; Insulin; Male; Muscle Proteins; Muscle, Skeletal; Nitrogen; Phenylalanine; Protein Biosynthesis; Tyrosine; Young Adult | 2015 |
The Effects of Acute Dopamine Precursor Depletion on the Cognitive Control Functions of Performance Monitoring and Conflict Processing: An Event-Related Potential (ERP) Study.
Topics: Cognition; Dopamine; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Humans; Male; Neuropsychological Tests; Phenylalanine; Psychomotor Performance; Reaction Time; Tyrosine | 2015 |
Probiotic Supplements Beneficially Affect Tryptophan-Kynurenine Metabolism and Reduce the Incidence of Upper Respiratory Tract Infections in Trained Athletes: A Randomized, Double-Blinded, Placebo-Controlled Trial.
Topics: Adult; Athletes; Austria; Biomarkers; Double-Blind Method; Female; Gastrointestinal Microbiome; Health Status; Humans; Kynurenine; Male; Neopterin; Phenylalanine; Physical Conditioning, Human; Physical Endurance; Physical Fitness; Probiotics; Respiratory Tract Infections; Risk Factors; Seasons; Time Factors; Tryptophan; Tyrosine; Young Adult | 2016 |
Dopamine and light: effects on facial emotion recognition.
Topics: Adult; Affect; Dopamine; Double-Blind Method; Emotions; Face; Female; Humans; Light; Male; Phenylalanine; Reaction Time; Seasonal Affective Disorder; Tyrosine; Young Adult | 2017 |
Dopamine and response selection: an Acute Phenylalanine/Tyrosine Depletion study.
Topics: Adult; Analysis of Variance; Decision Making; Dopamine; Electroencephalography; Evoked Potentials; Female; Humans; Inhibition, Psychological; Male; Motor Cortex; Phenylalanine; Reaction Time; Tyrosine; Young Adult | 2018 |
Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction.
Topics: Adult; Antioxidants; Humans; Liver; Liver Diseases; Male; Microbiota; MicroRNAs; Phenylalanine; Tyrosine; Ursodeoxycholic Acid; Vitamin E; Young Adult | 2018 |
Protein to Maximize Whole-Body Anabolism in Resistance-trained Females after Exercise.
Topics: Adult; Creatinine; Dietary Proteins; Energy Metabolism; Female; Humans; Muscle Proteins; Muscle, Skeletal; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Prospective Studies; Resistance Training; Tyrosine; Urea; Young Adult | 2019 |
Quantification of the flux of tyrosine pathway metabolites during nitisinone treatment of Alkaptonuria.
Topics: Adult; Alkaptonuria; Cyclohexanones; Female; Homogentisic Acid; Humans; Male; Middle Aged; Nitrobenzoates; Phenylalanine; Pigments, Biological; Tandem Mass Spectrometry; Tyrosine | 2019 |
Preliminary evidence for an association between intake of high-fat high-sugar diet, variations in peripheral dopamine precursor availability and dopamine-dependent cognition in humans.
Topics: Adult; Body Mass Index; Brain; Cognition; Cross-Over Studies; Diet; Diet, High-Fat; Dietary Fats; Dopamine; Double-Blind Method; Female; Humans; Intelligence; Learning; Memory, Short-Term; Phenylalanine; Psychomotor Performance; Sugars; Tyrosine; Young Adult | 2020 |
Essential amino acid-enriched whey enhances post-exercise whole-body protein balance during energy deficit more than iso-nitrogenous whey or a mixed-macronutrient meal: a randomized, crossover study.
Topics: Adult; Amino Acids, Essential; Body Mass Index; Cross-Over Studies; Dietary Proteins; Double-Blind Method; Energy Intake; Exercise; Female; Food, Fortified; Humans; Insulin; Male; Meals; Muscle Proteins; Nutrients; Phenylalanine; Postprandial Period; Proteins; Time Factors; Tyrosine; Whey; Young Adult | 2021 |
Neonatal Piglets Can Synthesize Adequate Creatine, but Only with Sufficient Dietary Arginine and Methionine, or with Guanidinoacetate and Excess Methionine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Animals, Newborn; Arginine; Creatine; Diet; Drug Tapering; Female; Glycine; Isotope Labeling; Male; Methionine; Phenylalanine; Swine; Tyrosine | 2021 |
Effect of BH4 on blood phenylalanine and tyrosine variations in patients with phenylketonuria.
Topics: Adult; Biopterins; Brain; Child; Child, Preschool; Dried Blood Spot Testing; Female; Humans; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 2021 |
Continuous oral stable isotope ingestion to measure whole-body protein turnover.
Topics: Adult; Cross-Over Studies; Eating; Female; Humans; Isotopes; Male; Phenylalanine; Proteins; Tyrosine | 2022 |
Short-Term Supplementation of Sodium Nitrate vs. Sodium Chloride Increases Homoarginine Synthesis in Young Men Independent of Exercise.
Topics: Arginine; Citrulline; Creatine; Creatinine; Dietary Supplements; Glutamates; Glutamine; Glycine; Homoarginine; Humans; Lysine; Male; Malondialdehyde; Methyltransferases; Nitrates; Nitrites; Ornithine; Phenylalanine; Sarcosine; Sodium Chloride; Tryptophan; Tyrosine | 2022 |
3906 other study(ies) available for phenylalanine and tyrosine
| Article | Year |
|---|---|
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste | 1987 |
Esters of N,N-disubstituted 2-hydroxyacetamides as a novel highly biolabile prodrug type for carboxylic acid agents.
Topics: Acetamides; Biotransformation; Carboxylic Acids; Half-Life; Humans; Indicators and Reagents; Kinetics; Structure-Activity Relationship | 1987 |
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis | 2001 |
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis | 2002 |
Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter.
Topics: Amino Acid Sequence; Animals; Base Sequence; Biological Transport, Active; Cloning, Molecular; DNA; Female; In Vitro Techniques; Kinetics; Male; Molecular Sequence Data; Monocarboxylic Acid Transporters; Oocytes; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Thyroid Hormones; Tissue Distribution; Xenopus laevis | 2003 |
Carbonic anhydrase activators: an activation study of the human mitochondrial isoforms VA and VB with amino acids and amines.
Topics: Amines; Amino Acids; Carbonic Anhydrases; Catalysis; Enzyme Activation; Humans; Kinetics; Mitochondrial Proteins; Protein Isoforms; Structure-Activity Relationship | 2007 |
Carbonic anhydrase activators: the first activation study of the human secretory isoform VI with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Carbonic Anhydrases; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation, Enzymologic; Humans; Molecular Sequence Data; Protein Isoforms; Protein Subunits | 2007 |
Carbonic anhydrase activators: activation of the human isoforms VII (cytosolic) and XIV (transmembrane) with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Carbonic Anhydrases; Enzyme Activation; Enzyme Activators; Humans; Isoenzymes; Molecular Sequence Data; Sequence Homology, Amino Acid | 2007 |
Carbonic anhydrase activators: activation of the human tumor-associated isozymes IX and XII with amino acids and amines.
Topics: Amines; Amino Acids; Antigens, Neoplasm; Carbonic Anhydrase IX; Carbonic Anhydrases; Conserved Sequence; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Sequence Data; Molecular Structure; Neoplasms; Sequence Alignment; Structure-Activity Relationship | 2008 |
Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines.
Topics: Amines; Amino Acids; Binding Sites; Carbonic Anhydrase III; Carbonic Anhydrase IV; Cell Membrane; Cytosol; Enzyme Activation; Histidine; Humans; Isoenzymes; Molecular Structure; Morpholines; Serotonin; Stereoisomerism | 2008 |
Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines.
Topics: Amines; Amino Acids; Archaea; Carbonic Anhydrases; Catalysis; Molecular Structure; Phenylalanine; Stereoisomerism; Tyrosine | 2008 |
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction | 2009 |
Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids.
Topics: Amino Acids; Candida albicans; Carbonic Anhydrases; Catalysis; Catalytic Domain; Cryptococcus neoformans; Drug Design; Enzyme Activation; Epinephrine; Humans; Kinetics; Models, Chemical; Protein Isoforms; Saccharomyces cerevisiae; Tryptophan | 2009 |
Carbonic anhydrase activators. Activation of the membrane-associated isoform XV with amino acids and amines.
Topics: Amines; Amino Acid Sequence; Amino Acids; Animals; Carbonic Anhydrases; Enzyme Activators; Humans; Kinetics; Mice; Molecular Sequence Data; Protein Isoforms; Recombinant Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship | 2009 |
Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids.
Topics: Amines; Amino Acids; Candida albicans; Carbonic Anhydrase I; Carbonic Anhydrases; Cryptococcus neoformans; Enzyme Activation; Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids.
Topics: Amines; Amino Acids; Candida glabrata; Carbonic Anhydrases; Catalytic Domain; Enzyme Activation; Humans; Kinetics; Models, Molecular; Recombinant Proteins; Structure-Activity Relationship | 2010 |
Carbonic anhydrase activators. The first activation study of a coral secretory isoform with amino acids and amines.
Topics: Amines; Amino Acids; Animals; Anthozoa; Carbonic Anhydrases; Enzyme Activation; Humans; Isoenzymes; Kinetics; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2010 |
The first activation study of a bacterial carbonic anhydrase (CA). The thermostable α-CA from Sulfurihydrogenibium yellowstonense YO3AOP1 is highly activated by amino acids and amines.
Topics: Amines; Amino Acids; Carbon Dioxide; Carbonic Anhydrases; Enzyme Activation; Gram-Negative Chemolithotrophic Bacteria; Kinetics | 2012 |
The extremo-α-carbonic anhydrase (CA) from Sulfurihydrogenibium azorense, the fastest CA known, is highly activated by amino acids and amines.
Topics: Amines; Amino Acids; Bacteria; Carbonic Anhydrases; Catalysis; Structure-Activity Relationship; Sulfur Compounds | 2013 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Carbonic anhydrase activators: Activation of the β-carbonic anhydrase from Malassezia globosa with amines and amino acids.
Topics: Amines; Amino Acids; Antifungal Agents; Carbonic Anhydrases; Dandruff; Dose-Response Relationship, Drug; Ligands; Malassezia; Molecular Structure; Structure-Activity Relationship | 2016 |
LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs.
Topics: Dose-Response Relationship, Drug; Humans; Large Neutral Amino Acid-Transporter 1; Models, Molecular; Molecular Structure; Phenylalanine; Structure-Activity Relationship; Tyrosine | 2016 |
LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates.
Topics: Blood-Brain Barrier; Carboxylic Acids; Chromatography, High Pressure Liquid; HEK293 Cells; Humans; Hydroxamic Acids; Large Neutral Amino Acid-Transporter 1; Magnetic Resonance Spectroscopy; Structure-Activity Relationship | 2016 |
Burkholderia pseudomallei γ-carbonic anhydrase is strongly activated by amino acids and amines.
Topics: Amines; Amino Acids; Burkholderia pseudomallei; Carbonic Anhydrases; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship | 2017 |
Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1).
Topics: Amino Acid Transport Systems; Antiporters; Escherichia coli Proteins; HEK293 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ligands; Molecular Docking Simulation; Phenylalanine; Stereoisomerism; Structural Homology, Protein; Structure-Activity Relationship; Substrate Specificity | 2018 |
3-Deoxy-D-arabino-heptulosonic acid 7-phosphate synthase mutants of Salmonella typhimurium.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Cell-Free System; Chromatography, DEAE-Cellulose; Chromosome Mapping; Genes; Glyoxal; Isoenzymes; Mutation; Phenylalanine; Salmonella typhimurium; Sugar Phosphates; Tetroses; Tryptophan; Tyrosine | 1975 |
Derepression of certain aromatic amino acid biosynthetic enzymes of Escherichia coli K-12 by growth in Fe3+-deficient medium.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Cell-Free System; Culture Media; Enzyme Repression; Escherichia coli; Glutamate Dehydrogenase; Glutamate Synthase; Hydro-Lyases; Hydroxybenzoates; Iron; Isoenzymes; Peptide Synthases; Phenylalanine; Prephenate Dehydratase; Shikimic Acid; Tryptophan; Tryptophan Synthase; Tyrosine | 1976 |
Role of D-tryptophan oxidase in D-tryptophan utilization by Escherichia coli.
Topics: Amino Acid Oxidoreductases; Cell-Free System; D-Amino-Acid Oxidase; Enzyme Repression; Genes; Histidine; Hydrogen-Ion Concentration; Mutation; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine; Tyrosine Transaminase | 1976 |
An enzyme common to histidine and aromatic amino acid biosynthesis in Bacillus subtilis.
Topics: Bacillus subtilis; Cell-Free System; Genes; Histidine; Mutation; p-Fluorophenylalanine; Phenylalanine; Transaminases; Tyrosine; Tyrosine Transaminase | 1976 |
Regulation of Chorismate mutase-prephenate dehydratase and prephenate dehydrogenase from alcaligenes eutrophus.
Topics: Alcaligenes; Cell-Free System; Chorismate Mutase; Enzyme Activation; Feedback; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; NAD; Oxidoreductases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Pyruvates; Temperature; Tryptophan; Tyrosine | 1976 |
Octopamine in mammalian brain: rapid post mortem increase and effects of drugs.
Topics: Animals; Brain; Chlordiazepoxide; Chlorpromazine; Fenclonine; Hydrazines; Imipramine; Iprindole; Kinetics; Male; Mice; Octopamine; Pargyline; Phenethylamines; Phenylalanine; Phenylethanolamine N-Methyltransferase; Postmortem Changes; Reserpine; Time Factors; Tyrosine | 1976 |
Altered prephenate dehydratase in phenylalanine-excreting mutants of Brevibacterium flavum.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Brevibacterium; Chorismate Mutase; Hydro-Lyases; Kinetics; Molecular Weight; Mutation; Phenylalanine; Prephenate Dehydratase; Tryptophan; Tyrosine | 1976 |
On the nature of an intermediate that is formed during the enzymatic conversion of phenylalanine to tyrosine.
Topics: Binding Sites; Dihydropteridine Reductase; Enzyme Activation; Gels; Hydrogen-Ion Concentration; Kinetics; NAD; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Protein Binding; Spectrophotometry, Ultraviolet; Tyrosine | 1976 |
Dynamics of the aromatic amino acid residues in the globular conformation of the basic pancreatic trypsin inhibitor (BPTI). I. 1H NMR studies.
Topics: Amino Acids; Aprotinin; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Tyrosine | 1976 |
Regulation of tyrosine and phenylalanine biosynthesis in Salmonella.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Chorismate Mutase; Drug Resistance, Microbial; Enzyme Repression; Genes, Regulator; Genetic Linkage; Mutation; p-Fluorophenylalanine; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Salmonella typhimurium; Tyrosine | 1976 |
Studies on phenylalanine and tyrosine hydroxylation by rat brain tyrosine hydroxylase.
Topics: Animals; Biopterins; Brain; Corpus Striatum; Kinetics; Male; Phenylalanine; Rats; Structure-Activity Relationship; Synaptosomes; Tyrosine; Tyrosine 3-Monooxygenase | 1976 |
Biosynthesis and metabolism of endogenous tyramine and its normal presence in sympathetic nerves.
Topics: Animals; Brain; Denervation; Dopamine beta-Hydroxylase; Hydroxydopamines; In Vitro Techniques; Male; Methyltyrosines; Pargyline; Phenylalanine; Rats; Salivary Glands; Sympathetic Nervous System; Time Factors; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase | 1976 |
Evidence for novel linkages in a glycoprotein involving beta-hydroxyphenylalanine and beta-hydroxytyrosine.
Topics: Amino Acid Oxidoreductases; Amino Acids; Binding Sites; Chromatography, Thin Layer; D-Amino-Acid Oxidase; Fusarium; Glycoproteins; Hydrolases; Hydroxy Acids; Phenylalanine; Protein Binding; Tyrosine | 1976 |
Conformational dependence on pH in tripeptides.
Topics: Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Oligopeptides; Phenylalanine; Protein Conformation; Tyrosine | 1976 |
Quantitative requirements for tyrosine, phenylalanine and tryptophan by the cotton aphid, Aphis gossypii (Glover).
Topics: Animals; Aphids; Diet; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Amino acid precursors of monoamine neurotransmitters and some factors influencing their supply to the brain.
Topics: Amino Acids, Essential; Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Carbon Radioisotopes; Histidine; Levodopa; Neurotransmitter Agents; Osmolar Concentration; Phenylalanine; Protein Precursors; Rats; Tryptophan; Tyrosine | 1976 |
Escherichia coli mutants deficient in the aspartate and aromatic amino acid aminotransferases.
Topics: Aspartate Aminotransferases; Aspartic Acid; Chromosome Mapping; Chromosomes, Bacterial; Coliphages; Escherichia coli; Genes; Leucine; Mutation; Phenylalanine; Transaminases; Transduction, Genetic; Tyrosine; Tyrosine Transaminase | 1977 |
Dopamine biosynthesis from L-tyrosine and L-phenylalanine in rat brain synaptosomes: preferential use of newly accumulated precursors.
Topics: Animals; Benserazide; Carbon Dioxide; Corpus Striatum; Dopamine; Hydrogen-Ion Concentration; Hypotonic Solutions; Male; Monoiodotyrosine; Olfactory Bulb; Phenylalanine; Rats; Synaptosomes; Time Factors; Tryptophan; Tyrosine | 1977 |
Photolysis of desmosine and isodesmosine by ultraviolet light.
Topics: Amino Acids; Animals; Cattle; Desmosine; Elastin; Hydrogen-Ion Concentration; Kinetics; Ligaments; Lysine; Phenylalanine; Photolysis; Spectrophotometry, Ultraviolet; Tyrosine; Ultraviolet Rays | 1977 |
Stabilisation of enzyme structures by inhibitors. A nuclear magnetic resonance study of the effect of phosphate on the acid unfolding of ribonuclease A.
Topics: Animals; Cattle; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen-Ion Concentration; Magnetics; Methionine; Pancreas; Phenylalanine; Phosphates; Ribonucleases; Spectrum Analysis; Tyrosine | 1977 |
Purification and properties of phenylalanine ammonia-lyase in cut-injured sweet potato.
Topics: Ammonia-Lyases; Cations, Divalent; Cinnamates; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Phenylalanine; Phenylalanine Ammonia-Lyase; Plants; Sulfhydryl Reagents; Temperature; Tyrosine | 1977 |
Ca2+ and Mg2+ dependent conformations of troponin C as determined by 1H and 19F nuclear magnetic resonance.
Topics: Alkylation; Binding Sites; Calcium; Fluorine; Histidine; Hydrogen-Ion Concentration; Kinetics; Magnesium; Magnetic Resonance Spectroscopy; Muscle Proteins; Phenylalanine; Protein Binding; Protein Conformation; Troponin; Tyrosine | 1977 |
Unfolding and refolding occur much faster for a proline-free proteins than for most proline-containing proteins.
Topics: Animals; Carps; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Kinetics; Muscle Proteins; Phenylalanine; Proline; Protein Denaturation; Tryptophan; Tyrosine | 1977 |
Stacking interactions between aromatic amino acids and adenine ring of ATP in zinc mediated ternary complexes.
Topics: Adenine; Adenosine Triphosphate; Amino Acids; Chemical Phenomena; Chemistry; Hydrogen-Ion Concentration; Indoles; Phenylalanine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Zinc | 1978 |
270-MHz 1H nuclear-magnetic-resonance study of Met-enkephalin in water. Conformational behaviour as a function of pH.
Topics: Amides; Endorphins; Enkephalins; Glycine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methionine; Molecular Conformation; Phenylalanine; Protons; Tyrosine; Water | 1979 |
The aromatic residues of bovine pancreatic ribonuclease studied by 1H nuclear magnetic resonance.
Topics: Animals; Binding Sites; Cattle; Cytidine Monophosphate; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Pancreas; Phenylalanine; Protein Conformation; Ribonucleases; Tyrosine; Uridine Monophosphate | 1979 |
Insulin, plasma aminoacid imbalance, and hepatic coma.
Topics: Amino Acids; Biological Availability; Brain; Hepatic Encephalopathy; Humans; Insulin; Insulin Secretion; Liver; Liver Circulation; Liver Cirrhosis; Methionine; Muscles; Phenylalanine; Portal System; Serotonin; Tryptophan; Tyrosine | 1975 |
New variant of phenylketonuria with progressive neurological illness unresponsive to phenylalanine restriction.
Topics: Biopterins; Child; Child, Preschool; Deglutition Disorders; Dihydropteridine Reductase; Female; Humans; Infant; Intellectual Disability; Male; Neuromuscular Diseases; Phenylalanine; Phenylketonurias; Seizures; Tyrosine | 1975 |
Penylalanine hydroxylation in phenylketonuria.
Topics: Child; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1976 |
Phenylalanine metabolism and intellectual functioning among carriers of phenylketonuria and hyperphenylalaninaemia.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Heterozygote; Humans; Intelligence; Male; Phenylalanine; Phenylketonurias; Tyrosine; Wechsler Scales | 1977 |
Serum-tyrosine in patients with hyperphenylalaninaemia.
Topics: Adolescent; Child; Child, Preschool; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1977 |
The eosin-sensitized photooxidation of substituted phenylalanines and tyrosines.
Topics: Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Phenylalanine; Photochemistry; Staining and Labeling; Tyrosine | 1977 |
Biosynthesis of noradrenaline in C1300 mouse neuroblastoma [proceedings].
Topics: Animals; Dihydroxyphenylalanine; Mice; Neoplasms, Experimental; Neuroblastoma; Norepinephrine; Phenylalanine; Tyrosine | 1978 |
Replacement of phenylalanine in gramicidin S by other amino acids.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Gramicidin; Phenylalanine; Tyrosine | 1979 |
Hyperammonaemia, plasma aminoacid imbalance, and blood-brain aminoacid transport: a unified theory of portal-systemic encephalopathy.
Topics: Amino Acids, Branched-Chain; Ammonia; Animals; Biological Transport; Blood-Brain Barrier; Brain; Dogs; Glucagon; Glutamine; Haplorhini; Hepatic Encephalopathy; Humans; Insulin; Liver Cirrhosis; Phenylalanine; Portacaval Shunt, Surgical; Rats; Tryptophan; Tyrosine | 1979 |
A novel nutritional approach to probe the molecular basis of behavior.
Topics: Amino Acids; Ammonia-Lyases; Animals; Behavior, Animal; Biogenic Amines; Brain; Haplorhini; Nutritional Physiological Phenomena; Phenylalanine; Phenylalanine Ammonia-Lyase; Tyrosine | 1978 |
Nutritional consequences of excess amino acid intake.
Topics: Amino Acids; Animals; Brain; Dietary Proteins; Liver; Nutritional Physiological Phenomena; Phenylalanine; Protein-Energy Malnutrition; Rats; Tryptophan; Tryptophan Oxygenase; Tyrosine | 1978 |
Aromatic substrate specificity of browning by cultures of the Legionnaires' disease bacterium.
Topics: Agar; Bacteria; Humans; Legionnaires' Disease; Melanins; Monophenol Monooxygenase; Phenylalanine; Phenylalanine Hydroxylase; Pigments, Biological; Tyrosine | 1979 |
[Therapy of hepatic encephalopathy. Modification of the plasma aminogram using amino acid infusions].
Topics: Aged; Amino Acids; Amino Acids, Branched-Chain; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Parenteral Nutrition; Phenylalanine; Time Factors; Tyrosine | 1978 |
Photoaffinity labelling of a tyrosine chemoreceptor in Pseudomonas aeruginosa.
Topics: Affinity Labels; Amino Acids; Carbohydrates; Chemotaxis; Kinetics; Phenylalanine; Photochemistry; Pseudomonas aeruginosa; Receptors, Drug; Tyrosine | 1979 |
Phenylketonuria in Indian children.
Topics: Brain Chemistry; Child, Preschool; Female; Humans; India; Infant; Male; Phenylalanine; Phenylketonurias; Sphingolipids; Tyrosine | 1978 |
Sulphr containing amino acids in chronic renal failure with particular reference to homocystine and cysteine-homocysteine mixed disulphide.
Topics: Amino Acids, Sulfur; Creatinine; Cysteine; Cystine; Dipeptides; Disulfides; Female; Homocysteine; Humans; Kidney Failure, Chronic; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Taurine; Tyrosine | 1979 |
[Investigation on the postoperative behavior of plasma amino acids in metabolically healthy patients. 1st communication (author's transl)].
Topics: Adult; Amino Acids; Blood Glucose; Cystine; Female; Glutamates; Humans; Hysterectomy; Methionine; Middle Aged; Parenteral Nutrition; Phenylalanine; Postoperative Period; Tyrosine | 1979 |
Biochemical effects of induced phenylketonuria in rats.
Topics: Amino Acids; Amniotic Fluid; Animals; Brain; Diet; Female; Fenclonine; Fetal Blood; Humans; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Rats; Serotonin; Tyrosine | 1975 |
Anacystis nidulans mutants resistant to aromatic amino acid analogues.
Topics: 4-Aminobutyrate Transaminase; Aldehyde-Lyases; Aminobutyrates; Ammonium Sulfate; Cell-Free System; Chemical Fractionation; Chromatography, Gel; Cyanobacteria; Drug Resistance, Microbial; Feedback; Heptoses; Hydroxyapatites; Kinetics; Mutation; p-Fluorophenylalanine; Phenylalanine; Phenylbutyrates; Phosphoenolpyruvate; Sugar Phosphates; Tetroses; Tyrosine | 1975 |
The effects of DL-p-chlorophenylalanine and DL-alpha-methyl-p-tyrosine on the brain catecholamine, serotonin and free amino acid contents in rat.
Topics: Amino Acids; Animals; Brain Chemistry; Catecholamines; Dopamine; Fenclonine; Histidine; Methionine; Methyltyrosines; Norepinephrine; Phenylalanine; Rats; Serotonin; Tyrosine | 1975 |
[Effects of beta-phenylethylamine derivatives on the central nervous system. (5) The effect of intracerebral administration of tyramine on head twitching in mice pre-treated with isocarboxazid].
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Brain; Drug Interactions; Fenclonine; Haloperidol; Head; Isocarboxazid; Male; Mice; Movement; Phenothiazines; Phenylalanine; Tyramine; Tyrosine | 1975 |
The regulation of phenylalanine hydroxylase in rat tissues in vivo. The maintenance of high plasma phenylalanine concentrations in suckling rats: a model for phenylketonuria.
Topics: Animals; Brain; Disease Models, Animal; Fenclonine; Humans; Kidney; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Tyrosine | 1976 |
The relevance of both plasma free tryptophan and insulin to rat brain tryptophan concentration.
Topics: Animals; Blood-Brain Barrier; Brain; Diabetes Mellitus; Insulin; Male; Phenylalanine; Rats; Streptozocin; Tryptophan; Tyrosine | 1976 |
Concentrations of phenylalanine and tyrosine in plasma and brain of rats treated with phenylalanine loads.
Topics: Animals; Brain; Brain Chemistry; Fenclonine; Kinetics; Phenylalanine; Rats; Tyrosine | 1976 |
Drugs altering insulin secretion: effects on plasma and brain concentrations of aromatic amino acids and on brain 5-hydroxytryptamine turnover.
Topics: Amino Acids; Animals; Brain Chemistry; Fatty Acids, Nonesterified; Hydroxyindoleacetic Acid; Insulin; Insulin Secretion; Male; Phentolamine; Phenylalanine; Propranolol; Rats; Serotonin; Streptozocin; Tolbutamide; Tryptophan; Tyrosine | 1977 |
Free amino acids in the tissues of rats with experimentally induced phenylketonuria.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Esculin; Fenclonine; Humans; Liver; Male; Phenylalanine; Phenylketonurias; Rats; Time Factors; Tyrosine | 1977 |
Isolation and preparation of pretyrosine, accumulated as a dead-end metabolite by Neurospora crassa.
Topics: Amino Acids, Dicarboxylic; Carbohydrate Metabolism; Cyclohexenes; Genes; Kinetics; Mutation; Neurospora; Neurospora crassa; Phenylalanine; Shikimic Acid; Temperature; Tyrosine | 1977 |
A new experimental model of hyperphenylalaninemia in rat. Effect of p-chlorophenylalanine and cotrimoxazole.
Topics: Animals; Disease Models, Animal; Drug Combinations; Fenclonine; Humans; Kidney; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Sulfamethoxazole; Trimethoprim; Tyrosine | 1977 |
Comparison of alpha-methylphenylalanine and p-chlorophenylalanine as inducers of chronic hyperphenylalaninaemia in developing rats.
Topics: Animals; Brain; Fenclonine; Liver; Metabolic Diseases; Methyltyrosines; Phenylalanine; Phenylalanine Hydroxylase; Rats; Tyrosine | 1978 |
Brain pyruvate kinase activity in PKU model systems.
Topics: Animals; Body Weight; Brain; Female; Fenclonine; Fetus; Humans; Organ Size; Phenylalanine; Phenylketonurias; Pregnancy; Pyruvate Kinase; Rats; Tyrosine | 1979 |
Tyrocidine synthetase system.
Topics: Aminoacylation; Asparagine; Bacillus; Cell Division; Chromatography, DEAE-Cellulose; Glutamine; Leucine; Ligases; Methods; Molecular Weight; Multienzyme Complexes; Ornithine; Phenylalanine; Proline; Time Factors; Tyrocidine; Tyrosine; Tyrothricin; Valine | 1975 |
Hemolysis and lysosomal activation by solid state tyrosine.
Topics: Animals; Bucladesine; Dialysis; Dose-Response Relationship, Drug; Erythrocytes; Glucose; Glucuronidase; Hemolysis; Humans; Liver; Lysosomes; Male; Phenylalanine; Propylene Glycols; Rats; Sucrose; Threonine; Tyramine; Tyrosine | 1975 |
Studies of individual carbon sites of proteins in solution by natural abundance carbon 13 nuclear magnetic resonance spectroscopy. Relaxation behavior.
Topics: Arginine; Carbon Isotopes; Cytochrome c Group; Fourier Analysis; Hemoglobins; Histidine; Magnetic Resonance Spectroscopy; Muramidase; Myoglobin; Phenylalanine; Protein Conformation; Proteins; Tryptophan; Tyrosine | 1975 |
Decrease of homovanillic, dihydroxyphenylacetic acid and cyclic-adenosine-3',5'-monophosphate content in the rat caudate nucleus induced by the acute administration of an aminoacid mixture lacking tyrosine and phenylalanine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Amino Acids; Animals; Basal Ganglia; Caudate Nucleus; Cerebellum; Cyclic AMP; Homovanillic Acid; Male; Phenylacetates; Phenylalanine; Rats; Tyrosine | 1976 |
The Richner-Hanhart syndrome: report of a case with associated tyrosinemia.
Topics: Adolescent; Conjunctiva; Cornea; Corneal Opacity; Endothelium; Epithelium; Humans; Inclusion Bodies; Intellectual Disability; Keratoderma, Palmoplantar; Male; Parakeratosis; Phenylalanine; Syndrome; Tyrosine | 1976 |
ESR and optical absorption studies on the copper (II) interaction with aromatic amino acids.
Topics: Amino Acids; Copper; Electron Spin Resonance Spectroscopy; Histidine; Ligands; Phenylalanine; Solutions; Spectrum Analysis; Temperature; Tryptophan; Tyrosine; Water | 1976 |
[Clinical and biochemical heterogenicity of phenylketonuria in adults].
Topics: Adolescent; Adult; Butyrylcholinesterase; Electron Transport Complex IV; Epilepsy; Female; Humans; Intelligence; Lipoproteins, LDL; Liver; Male; Middle Aged; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Psychopathology; Tyrosine | 1977 |
Specificity of DNA basic polypeptide interactions. II+ Influence of aromatic amino acid residues investigated with agarose bound lysine copolypeptides.
Topics: Base Sequence; Binding Sites; Chemical Phenomena; Chemistry; Clostridium perfringens; DNA, Bacterial; Lysine; Micrococcus; Peptides; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Tryptophan; Tyrosine | 1977 |
Effect of different amino acids on the phosphatase system of an ectoparasite: Poecilobdella granulosa.
Topics: Adenosine Triphosphatases; Alkaline Phosphatase; Amino Acids; Animals; Arginine; Central Nervous System; Digestive System; Glucose-6-Phosphatase; Histidine; Leeches; Nucleotidases; Phenylalanine; Phosphoric Monoester Hydrolases; Stereoisomerism; Tryptophan; Tyrosine | 1977 |
Genetics of the mammalian phenylalanine hydroxylase system: I. Isolation of phenylalanine hydroxylase-deficient tyrosine auxotrophs from rat hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Liver Neoplasms; Neoplasms, Experimental; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1977 |
[Electron paramagnetic resonance study of the products of the reaction between nitrogen oxides and several organic compounds].
Topics: Amino Acids; Butyrates; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Fatty Acids; Nitrogen Dioxide; Nitrous Oxide; Oleic Acids; Palmitic Acids; Phenylalanine; Stearic Acids; Tryptophan; Tyrosine | 1978 |
Homotransplantation of the liver in a patient with hepatoma and hereditary tyrosinemia.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Child; Female; Fructose-Bisphosphate Aldolase; Humans; Liver Neoplasms; Liver Transplantation; Phenylalanine; Porphobilinogen Synthase; Transplantation, Homologous; Tyrosine; Zinc | 1978 |
Tyrosyl-base-phenylalanyl intercalation in gene 5 protein-DNA complexes: proton nuclear magnetic resonance of selectively deuterated gene 5 protein.
Topics: Coliphages; DNA Helicases; DNA, Bacterial; DNA, Single-Stranded; Escherichia coli; Genes; Magnetic Resonance Spectroscopy; Models, Molecular; Nucleic Acid Conformation; Phenylalanine; Protein Binding; Protein Conformation; Tyrosine | 1978 |
Total assignments, including four aromatic residues, and sequence confirmation of the decapeptide tyrocidine A using difference double resonance. Qualitative nuclear overhauser effect criteria for beta turn and antiparallel beta-pleated sheet conformation
Topics: Amino Acid Sequence; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Tyrocidine; Tyrosine; Tyrothricin | 1979 |
Aromatic amino acid biosynthesis: regulation of shikimate kinase in Escherichia coli K-12.
Topics: Amino Acids; Enzyme Repression; Escherichia coli; Genes; Mutation; Phenylalanine; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Shikimic Acid; Tryptophan; Tyrosine | 1979 |
Interaction of aromatic residues of proteins with nucleic acids. Circular dichroism studies of the binding of oligopeptides to poly(adenylic acid).
Topics: Adenine Nucleotides; Binding Sites; Circular Dichroism; Hydrogen-Ion Concentration; Kinetics; Lysine; Molecular Conformation; Nucleic Acid Conformation; Oligopeptides; Phenylalanine; Polynucleotides; Protein Binding; Tyrosine | 1975 |
NMR investigations of the dynamics of the aromatic amino acid residues in the basic pancreatic trypsin inhibitor.
Topics: Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Binding; Protein Conformation; Temperature; Trypsin Inhibitors; Tyrosine | 1975 |
Assignment of aromatic amino acid PMR resonances of horse ferricytochrome c.
Topics: Animals; Circular Dichroism; Cytochrome c Group; Fishes; Histidine; Horses; Hydrogen-Ion Concentration; Iron; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Species Specificity; Tryptophan; Tyrosine | 1975 |
Proton magnetic resonance titration curves of the three histidine residues of staphylococcal protease.
Topics: Amino Acids; Histidine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Peptide Fragments; Peptide Hydrolases; Phenylalanine; Protein Conformation; Serine; Staphylococcus; Tyrosine | 1975 |
Actions of dopaminergic antagonists in the striatum.
Topics: Antidepressive Agents; Antipsychotic Agents; Butyrophenones; Carbon Radioisotopes; Corpus Striatum; Dibenzazepines; Dopamine; Dopamine Antagonists; Hallucinogens; Hypnotics and Sedatives; Norepinephrine; Phenothiazines; Phenylalanine; Receptors, Drug; Thioxanthenes; Tyrosine | 1975 |
Nuclear magnetic resonance studies of anaesthetic interactions with haemoglobin.
Topics: Chemical Phenomena; Chemistry; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Magnetic Resonance Spectroscopy; Methoxyflurane; Phenylalanine; Protein Binding; Protein Conformation; Protons; Tryptophan; Tyrosine | 1975 |
Aromatic amino acid transport in Yersinia pestis.
Topics: Azides; Bacterial Proteins; Biological Transport, Active; Chloramphenicol; Cyanides; Depression, Chemical; Dinitrophenols; Glucose; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Sulfhydryl Reagents; Temperature; Tritium; Tryptophan; Tyrosine; Yersinia pestis | 1975 |
Aromatic amino acid biosynthesis in Alcaligenes eutrophus H16. I. Properties and regulation of 3-deoxy-d-arabino heptulosonate 7-phosphate synthase.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Alcaligenes; Aldehyde-Lyases; Amino Acids; Cations, Divalent; Chromatography, DEAE-Cellulose; Corynebacterium; Dialysis; Drug Stability; Enzyme Repression; Feedback; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Phosphoenolpyruvate; Pseudomonas; Tetroses; Tryptophan; Tyrosine | 1975 |
[B-chain shortening of matrix-bound insulin by pepsin, I:Preparation and properties of bovine des-pentapeptide(B26-30) insulin (suthor's transl)].
Topics: Animals; Binding Sites; Cattle; Circular Dichroism; Crystallization; Hydrogen-Ion Concentration; Insulin; Oligopeptides; Pepsin A; Phenylalanine; Protein Binding; Protein Conformation; Tyrosine | 1975 |
Effect of phenylpyruvate and homogentisate on the formation of aromatic aminoacyl-tRNAs.
Topics: Animals; Brain; Cattle; Depression, Chemical; Homogentisic Acid; Phenylalanine; Phenylpyruvic Acids; RNA, Transfer; RNA, Transfer, Amino Acyl; Tryptophan; Tyrosine | 1977 |
Effect of dietetric factors on the growth of malignant melanomas.
Topics: Animals; Choroid Neoplasms; Cricetinae; Female; Humans; Melanoma; Phenylalanine; Tyrosine | 1977 |
A patient with malignant melanoma treated with a phenylalanine/tyrosine free diet.
Topics: Choroid Neoplasms; Humans; Male; Melanoma; Middle Aged; Phenylalanine; Tyrosine | 1977 |
Diet, genetics, and mental retardation interaction between phenylketonuric heterozygous mother and fetus to produce nonspecific diminution of IQ: evidence in support of the justification hypothesis.
Topics: Diet; Female; Heterozygote; Humans; Intelligence; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine; Wechsler Scales | 1978 |
Structural specificity of the carrier for L-tryptophan in rat cerebral cortex slices.
Topics: Animals; Biological Transport, Active; Cerebral Cortex; In Vitro Techniques; Isoleucine; Kynurenine; Leucine; Phenylalanine; Rats; Tryptophan; Tyrosine; Valine | 1979 |
Kinetics of tryptophan transport across the blood-brain barrier.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Kinetics; Mathematics; Phenylalanine; Rats; Tryptophan; Tyrosine | 1979 |
Electron beam excited emission spectra of organic molecular crystals: aromatic amino acids and proteins.
Topics: Amino Acids; Crystallization; Electron Probe Microanalysis; Histidine; Microscopy, Electron; Phenylalanine; Proteins; Spectrum Analysis; Tyrosine | 1978 |
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine | 1977 |
Dependence of 5-HT and catecholamine synthesis on concentrations of precursor amino-acids in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Haloperidol; Isoleucine; Kinetics; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine | 1978 |
[Metabolic disturbance of amino acids in peripheral lymphocytes from PKU (author's transl)].
Topics: Adult; Amino Acids; Cells, Cultured; Child; Child, Preschool; Female; Humans; Lymphocytes; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1979 |
A new variant form of phenylketonuria.
Topics: Adult; Child; Diseases in Twins; Drug Combinations; Drug Tolerance; Female; Humans; Intelligence; Male; Middle Aged; Pedigree; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Tyrosine | 1979 |
Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties.
Topics: Amino Acids; Bacterial Proteins; Chemical Phenomena; Chemistry; Deuterium; Enzyme Repression; Escherichia coli; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Specificity of elongation factor Tu from Escherichia coli with respect to attachment to the amino acid to the 2' or 3'-hydroxyl group of the terminal adenosine of tRNA.
Topics: Adenosine; Escherichia coli; Guanosine Triphosphate; Peptide Elongation Factors; Phenylalanine; Protein Binding; RNA, Transfer; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Structure-Activity Relationship; Tyrosine | 1977 |
Ternary complex formation between elongation factor Tu, GTP and aminoacyl-tRNA: an equilibrium study.
Topics: Calorimetry; Drug Stability; Escherichia coli; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Macromolecular Substances; Peptide Elongation Factors; Phenylalanine; RNA, Transfer, Amino Acyl; Serine; Temperature; Thermodynamics; Tyrosine | 1977 |
Regulation of aromatic amino acid transport systems in Escherichia coli K-12.
Topics: Amino Acids; Biological Transport, Active; Enzyme Repression; Escherichia coli; Genes, Regulator; Glucose; Mutation; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Mutations in the tryptophanyl-transfer ribonucleic acid ligase of E. coli causing temperature-sensitivity for growth.
Topics: Amino Acyl-tRNA Synthetases; Culture Media; Escherichia coli; Hot Temperature; Mutation; Phenotype; Phenylalanine; Tryptophan-tRNA Ligase; Tyrosine | 1978 |
Effect of mutation in the aromatic amino acid pathway on sporulation of Saccharomyces cerevisiae.
Topics: DNA; Genes; Mutation; Phenylalanine; Saccharomyces cerevisiae; Shikimic Acid; Spores, Fungal; Tryptophan; Tyrosine | 1978 |
Evidence for a direct role of tRNA in an amino acid transport system.
Topics: Biological Transport; Escherichia coli; Kinetics; Phenylalanine; RNA, Transfer; Spheroplasts; Structure-Activity Relationship; Tyrosine | 1979 |
The effect of dietary amino acids on immune reactivity.
Topics: Amino Acids; Amino Acids, Essential; Animals; Antibodies; Antibody Formation; Diet; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunity, Cellular; Male; Mice; Mice, Inbred Strains; Organ Size; Phenylalanine; Spleen; Tyrosine | 1978 |
Ribosomal RNA genes in the 56 minute region of the Escherichia coli chromosome.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Coliphages; DNA, Viral; Escherichia coli; Genes; Lysogeny; Nucleic Acid Hybridization; Operon; Phenylalanine; RNA, Bacterial; RNA, Ribosomal; Transduction, Genetic; Tyrosine | 1979 |
Unformylated initiator tRNA is not a signal for the stringent control of RNA synthesis.
Topics: Bacillus subtilis; Cell Division; Escherichia coli; Guanine Nucleotides; Kinetics; Leucine; Methionine; Phenylalanine; RNA, Transfer; Species Specificity; Transcription, Genetic; Trimethoprim; Tyrosine | 1977 |
Dual enzymatic routes to L-tyrosine and L-phenylalanine via pretyrosine in Pseudomonas aeruginosa.
Topics: Amino Acids, Dicarboxylic; Chloromercuribenzoates; Chorismate Mutase; Cyclohexenes; Drug Stability; Enzyme Activation; Hot Temperature; Hydro-Lyases; Kinetics; Molecular Weight; Phenylalanine; Prephenate Dehydratase; Pseudomonas aeruginosa; Transaminases; Tyrosine | 1977 |
The toxicity of melanin precursors.
Topics: Animals; Cattle; Dihydroxyphenylalanine; In Vitro Techniques; Melanins; Monophenol Monooxygenase; Nucleic Acid Synthesis Inhibitors; Phenylalanine; Quinones; Sulfhydryl Reagents; Tyrosine | 1978 |
Subclinical protein-energy malnutrition in under-privileged Ethiopian mothers and their newborn infants.
Topics: Adolescent; Adult; Developing Countries; Ethiopia; Female; Fetal Blood; Glycine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Isoleucine; Methionine; Phenylalanine; Pregnancy; Pregnancy Complications; Protein-Energy Malnutrition; Socioeconomic Factors; Tyrosine; Valine | 1978 |
Influences of exogenous intake and nitrogen balance on plasma and brain aromatic amino acid concentrations.
Topics: Amino Acids; Animals; Disease Models, Animal; Female; Liver Diseases; Nitrogen; Octopamine; Parenteral Nutrition; Phenylalanine; Portacaval Shunt, Surgical; Rats; Tryptophan; Tyrosine | 1978 |
Enzymological basis of reluctant auxotrophy for phenylalanine and tyrosine in Pseudomonas aeruginosa.
Topics: Enzyme Induction; Mutation; Phenylalanine; Pseudomonas aeruginosa; Transaminases; Tyrosine | 1978 |
Free and bound tryptophan in human plasma during the perinatal period.
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Infant, Premature; Labor, Induced; Male; Phenylalanine; Pregnancy; Protein Binding; Serum Albumin; Tryptophan; Tyrosine | 1979 |
Effects of serum on membrane transport. III. Serum and inhibition of lysine transport.
Topics: Amino Acids; Animals; Biological Transport, Active; Cell Membrane; Depression, Chemical; Glutamine; Kinetics; Lysine; Macrophages; Phenylalanine; Rabbits; Tyrosine | 1979 |
Crystals of a bovine neurophysin II-dipeptide amide complex.
Topics: Animals; Cattle; Crystallography; Dipeptides; Neurophysins; Phenylalanine; Protein Binding; Tyrosine | 1979 |
Inhibitory effect of tripeptides containing L-Phe-L-Tyr on neuronal excitability.
Topics: Animals; In Vitro Techniques; Membrane Potentials; Neurons; Oligopeptides; Phenylalanine; Snails; Tyrosine | 1979 |
Streptozotocin-induced diabetes in rats decreases brain tryptophan uptake after portacaval anastomosis.
Topics: Animals; Brain; Diabetes Mellitus, Experimental; Isoleucine; Leucine; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Tryptophan; Tyrosine; Valine | 1979 |
Selective substitution of 2H and 3H into aromatic amino acids catalyzed by Raney nickel.
Topics: Chemical Phenomena; Chemistry; Deuterium; Magnetic Resonance Spectroscopy; Nickel; Phenylalanine; Tritium; Tryptophan; Tyrosine | 1979 |
Effects of reduced renal mass and dietary protein intake on amino acid release and glucose uptake by rat muscle in vitro.
Topics: Alanine; Amino Acids; Animals; Dietary Proteins; Forelimb; Glucose; Glutamates; Glutamine; In Vitro Techniques; Lactates; Male; Muscles; Nephrectomy; Phenylalanine; Pyruvates; Rats; Tyrosine | 1979 |
Biochemical properties and immunogenicity of L-phenylalanine ammonia-lyase: effects on tumor-bearing mice.
Topics: Ammonia-Lyases; Animals; Antibody Formation; Cyclophosphamide; Female; Immunosuppression Therapy; Mice; Neoplasms, Experimental; Phenylalanine; Phenylalanine Ammonia-Lyase; Tyrosine | 1979 |
Protein synthesis in isolated human skeletal muscle tissue: evaluation of an experimental model.
Topics: Aurintricarboxylic Acid; Bone and Bones; Cold Temperature; Humans; Insulin; Leucine; Models, Biological; Muscles; Phenylalanine; Protein Biosynthesis; Puromycin; RNA; Tyrosine; Uridine | 1979 |
The effect of insulin on elder phenylketonuric patients.
Topics: Adolescent; Adult; Catecholamines; Female; Humans; Injections, Intramuscular; Insulin; Male; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1979 |
Intracellular phenylalanine and tyrosine concentrations in 19 heterozygotes for phenylketonuria (PKU) and 26 normals. Do the higher values in heterozygotes explain their lowered intellectual level?
Topics: Female; Heterozygote; Humans; Intelligence; Lymphocytes; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1979 |
Two components of chorismate mutase in Brevibacterium flavum.
Topics: Brevibacterium; Chorismate Mutase; Isomerases; Kinetics; Macromolecular Substances; Molecular Weight; Mutation; Phenylalanine; Species Specificity; Tyrosine | 1979 |
[Enzymes of the aromatic amino acid biosynthesis in Hansenula henricii: determination and characterization of the pretyrosine pathway enzymes].
Topics: Ascomycota; Cell-Free System; Oxidoreductases; Phenylalanine; Pichia; Transaminases; Tyrosine | 1979 |
Screening for PKU heterozygosity in bipolar affectively ill patients.
Topics: Bipolar Disorder; Female; Genetic Carrier Screening; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1979 |
[Laboratory tests for aromatic amino acid metabolism].
Topics: Humans; Methods; Phenylalanine; Tryptophan; Tyrosine | 1979 |
Relative inability of mother and child to convert phenylalanine of tyrosine--a possible cause of nonspecific mental retardation.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Heterozygote; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1979 |
Creatine kinase. Nuclear magnetic resonance and fluorescence evidence for interaction of adenosine 5'-diphosphate with aromatic residue(s).
Topics: Adenosine Diphosphate; Animals; Binding Sites; Creatine Kinase; Fourier Analysis; Kinetics; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Binding; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1979 |
The conversion of [3H] tryptophan to 5-[3H] hydroxytryptamine in mouse brain following depletion of phenylalanine and tyrosine.
Topics: Ammonia-Lyases; Animals; Biological Transport; Brain; Dopamine; Kinetics; Mice; Norepinephrine; Phenylalanine; Phenylalanine Ammonia-Lyase; Serotonin; Tritium; Tryptophan; Tyrosine | 1979 |
[The evaluation of the kinetic constants of enzyme-catalysed reaction with the use of integrated rate equation (author's transl)].
Topics: Ammonia-Lyases; Chymotrypsin; Dipeptides; Histidine; Histidine Ammonia-Lyase; Humans; Hydrolysis; Kinetics; Lysine; Models, Biological; Phenylalanine; Regression Analysis; Substrate Specificity; Trypsin; Tryptophan; Tyrosine | 1979 |
Direct evidence for the presence of beta-hydroxyphenylalanine and beta-hydroxytyrosine in cutinase from Fusarium solani pisi.
Topics: Chemical Phenomena; Chemistry; Fungal Proteins; Fusarium; Glycoproteins; Hydrolases; Hydroxy Acids; Membrane Lipids; Phenylalanine; Tyrosine | 1979 |
[Free amino acids in calf embryos].
Topics: Alanine; Amino Acids; Animals; Cattle; Embryo, Mammalian; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1979 |
Linkage analysis using heterozygote detection in phenylketonuria.
Topics: Chromosome Mapping; Ethnicity; Female; Genetic Carrier Screening; Genetic Linkage; Heterozygote; Humans; Male; Pedigree; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 1979 |
[The validity of a screening test of heterozygotes for phenylketonuria].
Topics: Genetic Carrier Screening; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1979 |
Dietary restriction in inborn errors of amino acid metabolism.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cystinosis; Food, Formulated; Histidine; Homocystinuria; Humans; Infant; Infant Food; Infant, Newborn; Intelligence; Maple Syrup Urine Disease; Phenylalanine; Phenylketonurias; Tyrosine | 1979 |
Mammalian melanocytes do not use phenylalanine for melanin synthesis.
Topics: Animals; Cell Line; Cricetinae; Cycloheximide; Leucine; Melanins; Melanocytes; Melanoma; Phenylalanine; Pronase; Thiouracil; Tyrosine | 1977 |
Decreased foetal amino acid uptake, brain pyruvate kinase and intrauterine damage in maternal PKU.
Topics: Amino Acids; Animals; Brain; Female; Fetus; Hexokinase; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pyruvate Kinase; Rats; Succinate Dehydrogenase; Tryptophan; Tyrosine | 1977 |
[The problem in the differential diagnosis of various forms of hyperphenylalaninemia and in its diet therapy].
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1977 |
Effects of dietary tyrosine, phenylalanine, and tryptophan on aggression in mice.
Topics: Aggression; Animals; Diet; Humans; Male; Mice; Motor Activity; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Induced PKU in rats: effects of age and melatonin treatment.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Female; Humans; Learning; Melatonin; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Time Factors; Tyrosine | 1977 |
[Comparative effects of different inhibitors of phenylalanine hydroxylase and dihydropteridine reductase. In vivo and in vitro study in rats].
Topics: Animals; Dihydropteridine Reductase; Disease Models, Animal; Humans; Liver; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Tyrosine | 1978 |
Diurnal variations in plasma concentrations of tryptophan, tryosine, and other neutral amino acids: effect of dietary protein intake.
Topics: Adult; Alanine; Amino Acids; Circadian Rhythm; Dietary Proteins; Glycine; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
Diurnal variations in plasma neutral amino acid concentrations among patients with cirrhosis: effect of dietary protein.
Topics: Adult; Aged; Amino Acids; Circadian Rhythm; Dietary Proteins; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis, Alcoholic; Male; Methionine; Middle Aged; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1979 |
[Metabolism of amino acids and brain proteins in phenylketonuria].
Topics: Animals; Brain; Catecholamines; Chemical Phenomena; Chemistry; Glycolysis; Humans; Nerve Tissue Proteins; Phenylalanine; Phenylketonurias; Pyridoxine; Serotonin; Tryptophan; Tyrosine | 1979 |
Experimental phenylketonuria: replacement of carboxyl terminal tyrosine by phenylalanine in infant rat brain tubulin.
Topics: Amino Acid Sequence; Animals; Brain; Cytoplasm; Disease Models, Animal; Humans; Microtubules; Phenylalanine; Phenylketonurias; Protein Binding; Rats; Tubulin; Tyrosine | 1979 |
[Blood tyrosine in the newborn. IV. Behavior of phenylalanine in relation to birth weight, to blood tyrosine and protein supply].
Topics: Animals; Birth Weight; Dietary Proteins; Gestational Age; Glycine max; Humans; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Milk; Milk, Human; Phenylalanine; Tyrosine | 1978 |
Effect of aromatic acids on the influx of aromatic amino acids in rat brain slices.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Homogentisic Acid; In Vitro Techniques; Kinetics; Phenylalanine; Phenylpyruvic Acids; Rats; Tryptophan; Tyrosine | 1977 |
Serum tyrosine within the first hour after an oral load of phenylalanine.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Female; Heterozygote; Humans; Infant; Male; Middle Aged; Phenylalanine; Phenylketonurias; Tyrosine | 1977 |
Hypertyrosinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Diagnosis, Differential; Female; Humans; Infant; Infant, Newborn; Male; Mass Screening; Phenylalanine; Tyrosine | 1977 |
In vivo metabolism of deutero-L-phenylalanine and deutero-L-tyrosine in normal and in various tumor-bearing rats.
Topics: Animals; Biopterins; Deuterium; Female; Hydroxylation; Kinetics; Liver Neoplasms, Experimental; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Sarcoma, Experimental; Tyrosine | 1977 |
On the levels of phenylalanine, tyrosine and tetrahydrobiopterin in the blood of tumor-bearing organisms.
Topics: Animals; Biopterins; Blood Proteins; Female; Humans; Hydroxylation; Male; Neoplasms; Neoplasms, Experimental; Phenylalanine; Protein Binding; Pteridines; Rats; Tyrosine | 1977 |
Increase in large neutral amino acid transport into brain by insulin.
Topics: Amino Acids; Animals; Brain; Fatty Acids, Nonesterified; Glucose; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Tryptophan; Tyrosine; Valine | 1978 |
The labelling of urinary acids after oral doses of deuterated L-phenylalanine and L-tyrosine in normal subjects. Quantitative studies with implications for the deuterated phenylalanine load test in phenylketonuria.
Topics: Acids; Adult; Amino Acids; Deuterium; Female; Humans; Male; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1978 |
Abnormalities of phenylalanine and tyrosine kinetics. Significance in septic and nonseptic burned patients.
Topics: Adult; Burns; Fasting; Humans; Kinetics; Klebsiella Infections; Liver; Middle Aged; Muscle Proteins; Muscles; Phenylalanine; Pseudomonas Infections; Sepsis; Tyrosine | 1978 |
In vivo studies of the phenylalanine-4-hydroxylase system in hyperphenylalaninemics and phenylketonurics.
Topics: Adult; Child; Child, Preschool; Female; Humans; Infant; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1978 |
Tryptophan excretion by a bradytroph of Hansenula polymorpha growing in methanol.
Topics: Ascomycota; Chorismate Mutase; Methanol; Mutation; Phenylalanine; Pichia; Tryptophan; Tyrosine | 1978 |
Biosynthesis of chloramphenicol in Streptomyces sp. 3022a. Properties of an aminotransferase accepting p-aminophenylalanine as a substrate.
Topics: Amino Acids, Diamino; Cell-Free System; Chloramphenicol; Phenylalanine; Stereoisomerism; Streptomyces; Substrate Specificity; Transaminases; Tyrosine | 1978 |
What to do with the Guthrie test report.
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Mass Screening; Phenylalanine; Phenylketonurias; Tyrosine | 1978 |
Capability of tubulin and microtubules to incorporate and to release tyrosine and phenylalanine and the effect of the incorporation of these amino acids on tubulin assembly.
Topics: Animals; Brain; Carboxypeptidases; Cytosol; Glycoproteins; Microtubules; Phenylalanine; Rats; Tubulin; Tyrosine | 1978 |
Phenylketonuria heterozygote detection in families with affected children.
Topics: Ethnicity; Female; Genetic Counseling; Heterozygote; Humans; Indiana; Male; Michigan; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Selection, Genetic; Sex Factors; Tryptophan; Tyrosine | 1978 |
[Cutaneous dyschromia in three cases of phenylketonuria. Quantitative ultrastructural study of the basal layer of the epidermis (author's transl)].
Topics: Child; Epidermis; Erythema; Female; Hair Color; Humans; Keratins; Male; Melanins; Phenylalanine; Phenylketonurias; Pigmentation Disorders; Tyrosine | 1978 |
Effects of essential amino acid deficiencies on syngeneic tumor immunity and carcinogenesis in mice.
Topics: Amino Acids, Essential; Animals; Female; Isoleucine; Leucine; Methylcholanthrene; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Transplantation Immunology; Transplantation, Isogeneic; Tyrosine | 1978 |
Some characteristics of p-fluorophenylalanine-resistant mutants of Penicillium cyclopium.
Topics: Alkaloids; Drug Resistance, Microbial; Fungal Proteins; Mutation; p-Fluorophenylalanine; Penicillium; Phenylalanine; Spores, Fungal; Tyrosine | 1978 |
Dietary treatment of tyrosinemia type I: importance of methionine restriction.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diet; Dietary Proteins; Female; Humans; Infant; Infant Food; Methionine; Oxygenases; Phenylalanine; Tyrosine | 1978 |
Second-derivative spectroscopy of proteins. A method for the quantitative determination of aromatic amino acids in proteins.
Topics: Phenylalanine; Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1978 |
Plasma amino acid profiles in patients with fulminant hepatic failure treated by repeated polyacrylonitrile membrane hemodialysis.
Topics: Acrylonitrile; Adult; Amino Acids; Amino Acids, Branched-Chain; Female; Hepatic Encephalopathy; Humans; Male; Phenylalanine; Proline; Renal Dialysis; Tyrosine | 1978 |
Changes in free amino acids and peptides in the haemolymph of Glossina austeni during the reproductive cycle.
Topics: Amino Acids; Animals; Aspartic Acid; Female; Hemolymph; Hydrolysis; Lysine; Peptides; Phenylalanine; Pregnancy; Tsetse Flies; Tyrosine | 1978 |
Plasma ratio of valine, leucine and isoleucine to phenylalanine and tyrosine in liver disease.
Topics: Adult; Amino Acids; Female; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis; Liver Diseases; Male; Middle Aged; Phenylalanine; Tyrosine; Valine | 1978 |
Post-natal changes in the transport of aromatic amino acids into the brain [proceedings].
Topics: Aging; Amino Acids; Animals; Biological Transport; Brain; Phenylalanine; Rats; Tryptophan; Tyrosine | 1978 |
Mitochondrial and cytosolic aspartate aminotransferase from chicken: activity toward aromatic amino acids.
Topics: Animals; Aspartate Aminotransferases; Chickens; Cytosol; Kinetics; Mitochondria, Heart; Myocardium; Phenylalanine; Substrate Specificity; Tryptophan; Tyrosine | 1978 |
[Abnormalities in amino acid metabolism (author's transl)].
Topics: Amino Acid Metabolism, Inborn Errors; Humans; Infant; Infant, Newborn; Phenylalanine; Tyrosine | 1978 |
Directed integration of bacteriophage lambda in an F lac transposition Hfr strain of Escherichia coli: isolation and characterization of specialized transducing phages for the phenylalanine and tyrosine operons.
Topics: Chromosome Mapping; Coliphages; Escherichia coli; Galactosidases; Gene Frequency; Genotype; Lactose; Lysogeny; Mutation; Operon; Phenylalanine; Species Specificity; Transduction, Genetic; Tyrosine | 1976 |
Comparison of isotope labeling patterns of purines in three specific transfer RNAs.
Topics: Base Sequence; Binding Sites; Escherichia coli; Isoleucine; Isotope Labeling; Magnesium; Nucleic Acid Conformation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Tritium; Tyrosine | 1976 |
A recombination-dependent replicating instability in Salmonella typhimurium.
Topics: DNA Replication; Mutation; Phenylalanine; Recombination, Genetic; Salmonella typhimurium; Tryptophan; Tyrosine | 1976 |
The regulation of diaminopimelate decarboxylase activity in Escherichia coli strain w.
Topics: Aspartate Kinase; Carboxy-Lyases; Diaminopimelic Acid; Enzyme Repression; Escherichia coli; Lysine; Mutation; Phenylalanine; Pyridoxine; Stereoisomerism; Threonine; Tryptophan; Tyrosine | 1976 |
Azide-dependent mutants in E. coli K12.
Topics: Azides; Chromosome Mapping; Escherichia coli; Genes; Mutation; Operon; Phenylalanine; Threonine; Tryptophan; Tyrosine | 1976 |
Synthesis and microbiological activities of some monohalogenated analogs of tyrosine.
Topics: Bromine; Chlorine; Enterococcus faecalis; Escherichia coli; Lactobacillus; Microbial Sensitivity Tests; Phenylalanine; Tyrosine | 1975 |
Prephenate dehydrogenase from Pseudomonas aeruginosa is a regulated component of the channel-shuttle mechanism controlling tyrosine-phenylalanine synthesis.
Topics: Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Kinetics; Oxidoreductases; Phenylalanine; Prephenate Dehydrogenase; Pseudomonas aeruginosa; Tyrosine | 1975 |
Kinetics of affinity labeling the L-tyrosine/L-phenylalanine transport system in Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Biological Transport, Active; Ketones; Kinetics; Phenylalanine; Time Factors; Tyrosine | 1975 |
Versatile properties of a nonsaturable, homogeneous transport system in Bacilus subtilis: genetic, kinetic, and affinity labeling studies.
Topics: Amino Acids; Bacillus subtilis; Biological Transport, Active; Kinetics; Phenylalanine; Tyrosine | 1975 |
The role of plasma amino acids in hepatic encephalopathy.
Topics: Albumins; Amino Acids; Ammonia; Animals; Arginine; Blood Urea Nitrogen; Dogs; Glucose; Glutamates; Hepatic Encephalopathy; Isoleucine; Leucine; Liver Function Tests; Methionine; Parenteral Nutrition; Phenylalanine; Portacaval Shunt, Surgical; Threonine; Tryptophan; Tyrosine; Valine | 1975 |
Alterations in plasma copper, zinc, amino acids, and seromucoid during Rocky Moutain spotted fever in guinea pigs.
Topics: Amino Acids; Animals; Copper; Fever; Guinea Pigs; Mucoproteins; Phenylalanine; Rickettsia rickettsii; Rocky Mountain Spotted Fever; Time Factors; Tyrosine; Zinc | 1976 |
Purification and characterization of tRNAMet-f, tRNAPhe and tRNATyr2 from Baccillus subtilis.
Topics: Bacillus subtilis; Hot Temperature; Magnesium; N-Formylmethionine; Nucleic Acid Denaturation; Phenylalanine; Ribonucleotides; RNA, Transfer; Tyrosine | 1976 |
Testing the protein error hypothesis of ageing in Drosophila.
Topics: Aging; Animals; Drosophila melanogaster; Ethionine; Half-Life; Male; Phenylalanine; Proteins; Tryptophan; Tyrosine | 1976 |
The significance and mechanism of an increased serum phenylalanine-tyrosine ratio during infection.
Topics: Animals; Bacterial Infections; Body Composition; Carbon Dioxide; Feces; Haplorhini; Humans; Infections; Liver; Macaca mulatta; Male; Muscles; Phenylalanine; Pneumococcal Infections; Rats; Respiration; Rickettsia Infections; Tularemia; Tyrosine; Virus Diseases | 1976 |
Effects of rapid depletion of phenylalanine and tyrosine on sleep and behavior.
Topics: Animals; Behavior, Animal; Brain; Brain Chemistry; Conditioning, Operant; Dopamine; Haplorhini; Male; Methods; Norepinephrine; Phenylalanine; Phenylalanine Ammonia-Lyase; Rats; Saimiri; Serotonin; Sleep; Time Factors; Tyrosine | 1976 |
[The traps of Guthrie's test].
Topics: Age Factors; Bacillus subtilis; Birth Weight; Blood Bactericidal Activity; False Positive Reactions; Gestational Age; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Mass Screening; Metabolism; Milk Proteins; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1976 |
Protein degradation and amino acid metabolism in autolyzing rabbit myocardium.
Topics: Alanine; Amino Acids; Ammonia; Animals; Autolysis; Ethanolamines; Glutamates; In Vitro Techniques; Lactates; Muscle Proteins; Myocardium; Phenylalanine; Rabbits; Taurine; Tyrosine; Urea | 1977 |
Transport of tyrosine, phenylalanine, tryptophan and glycine in neuroblastoma clones.
Topics: Amino Acids; Biological Transport; Clone Cells; Dinitrophenols; Glycine; Kinetics; Neuroblastoma; Phenylalanine; Sodium; Temperature; Tryptophan; Tyrosine | 1977 |
Phenylalanine-tyrosine deficiency syndrome as a complication of the management of hereditary tyrosinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Humans; Infant; Liver Cirrhosis; Male; Phenylalanine; Tyrosine | 1977 |
[Effect of urethane (DAB-6 product), hexobarbital-Na and pentobarbital-Na on the amino acid concentrations in blood serum of rats. I. Communication (author's transl)].
Topics: Amino Acids; Animals; Arginine; Chromatography, Ion Exchange; Hexobarbital; Isoleucine; Leucine; Lysine; Male; Methionine; Methods; Ornithine; Pentobarbital; Phenylalanine; Rats; Taurine; Tryptophan; Tyrosine; Urethane | 1977 |
Heterozygote detection in phenylketonuria.
Topics: Child, Preschool; Female; Heterozygote; Humans; Infant; Infant, Newborn; Male; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1977 |
Synthesis of specific deuterium labeled tyrosine and phenylalanine derivatives and their use in the total synthesis of [8-arginine]vasopressin derivatives: The separation of diastereomeric [8-arginine]vasopressin derivatives by partition chromatography1,2
Topics: Arginine Vasopressin; Chromatography; Deuterium; Isotope Labeling; Phenylalanine; Stereoisomerism; Tyrosine; Vasopressins | 1977 |
Co-oligopeptides of aromatic amino acids and glycine with variable distance between the aromatic residues. VII. Enzymatic synthesis of N-protected peptide amides.
Topics: Amides; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Glycine; Oligopeptides; Phenylalanine; Tryptophan; Tyrosine | 1977 |
The aggregation of basic polypeptide residues bound to heparin.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Heparin; Peptides; Phenylalanine; Polylysine; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tyrosine | 1977 |
Precursor incroporation experiments in Papaver alkaloid biosynthesis. I. Papaver bracteatum lindl.
Topics: Alkaloids; Carbon Radioisotopes; Glycine; Isotope Labeling; Papaver; Phenylalanine; Plants, Medicinal; Thebaine; Time Factors; Tyrosine; Urea | 1977 |
Dopa and dopamine formation from phenylalanine in human brain.
Topics: Aged; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Female; Humans; In Vitro Techniques; Male; Middle Aged; Phenylalanine; Polyethylene Glycols; Rats; Tyrosine | 1977 |
[Values of phenylalanine and tyrosine in premature infants].
Topics: Humans; Infant, Newborn; Infant, Premature; Phenylalanine; Tyrosine | 1977 |
Citrulline as a diagnostic parameter and a major amino acid constituent of cerebrospinal fluid in hepatic coma.
Topics: Argininosuccinate Synthase; Chromatography, Thin Layer; Citrulline; Glutamine; Hepatic Encephalopathy; Humans; Methionine; Phenylalanine; Tyrosine | 1977 |
On indications for treatment of the hyperphenylalaninemic neonate.
Topics: Denmark; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Mass Screening; Phenylalanine; Phenylketonurias; Tyrosine | 1977 |
Desmosine peptides: amino acid sequences and the role of these sequences in crosslink formation.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Aorta; Cattle; Desmosine; Elastin; Humans; Ligaments; Lysine; Peptides; Phenylalanine; Protein Conformation; Swine; Tropoelastin; Tyrosine | 1977 |
Different phenotypes for phenylalanine hydroxylase deficiency.
Topics: Adult; Child, Preschool; Diet; Heterozygote; Homozygote; Humans; Infant; Infant, Newborn; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1977 |
[Screening test for hyperphenylalaninemias and tyrosinemias : fluorometric micromethods for quantitative determination of phenylalanine and tyrosine by means of the same auto-analyzer system].
Topics: Amino Acid Metabolism, Inborn Errors; Autoanalysis; Fluorometry; Humans; Indicators and Reagents; Infant, Newborn; Phenylalanine; Tyrosine | 1977 |
Phenylketonuria: a new method for the simultaneous determination of plasma phenylalanine and tyrosine.
Topics: Humans; Phenylalanine; Phenylalanine Ammonia-Lyase; Phenylketonurias; Rhodotorula; Tyrosine | 1977 |
Dopamine turnover: studies with 18O2.
Topics: Animals; Brain; Dopamine; In Vitro Techniques; Kinetics; Oxygen Consumption; Oxygen Isotopes; Phenylalanine; Rats; Tyrosine | 1977 |
Kinetics of intravenous administered L-phenylalanine in patients with cirrohosis of the liver.
Topics: Adult; Aged; Amino Acids; Female; Galactose; Humans; Kinetics; Liver Cirrhosis; Male; Mathematics; Middle Aged; Phenylalanine; Tyrosine | 1977 |
Phenylalanine requirement of the weanling pig and its relationship to tyrosine.
Topics: Animal Feed; Animals; Body Weight; Glutamates; Nutritional Requirements; Phenylalanine; Swine; Tyrosine; Weaning; Zea mays | 1977 |
Affinity chromatography and inhibition of chorismate mutase-prephenate dehydrogenase by derivatives of phenylalanine and tyrosine.
Topics: Chromatography, Affinity; Hydro-Lyases; Phenylalanine; Prephenate Dehydratase; Sepharose; Tyrosine | 1977 |
Differential partitioning of tRNAs between micellar and aqueous phases: a convenient gel filtration method for separation of tRNAs.
Topics: Cetrimonium Compounds; Chromatography, Gel; Glutamates; Glycine; Mathematics; Micelles; N-Formylmethionine; Phenylalanine; Quaternary Ammonium Compounds; RNA, Transfer; Surface Properties; Tyrosine | 1977 |
The pathways of oxalate formation from phenylalanine, tyrosine, tryptophan and ascorbic acid in the rat.
Topics: Animals; Ascorbic Acid; Carbon Dioxide; Carbon Radioisotopes; Isotope Labeling; Kinetics; Male; Oxalates; Phenylalanine; Rats; Respiration; Tryptophan; Tyrosine | 1977 |
Detection of heterozygotes for phenylketonuria. Total body phenylalanine clearance and concentrations of phenylalanine and tyrosine in the plasms of fasting subjects compared.
Topics: Adult; Contraceptives, Oral; Fasting; Female; Heterozygote; Homozygote; Humans; Kinetics; Male; Mathematics; Middle Aged; Phenylalanine; Phenylketonurias; Sex Factors; Tyrosine | 1977 |
Second derivative spectrophotometry as an effective tool for examining phenylalanine residues in proteins.
Topics: Phenylalanine; Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1977 |
Muscle amino acid arylpeptidases and their serum changes with exercise.
Topics: Adolescent; Adult; Alanine; Aminopeptidases; Glycine; Humans; Leucine; Male; Muscles; Phenylalanine; Physical Exertion; Proline; Running; Skiing; Tyrosine | 1977 |
Quantitation of deuterated and non-deuterated phenylalanine and tyrosine in human plasma using the selective ion monitoring method with combined gas chromatography-mass spectrometry. Application to the in vivo measurement of phenylalanine-4-monooxygenase
Topics: Chromatography, Gas; Humans; Mass Spectrometry; Methods; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1977 |
Dopamine formation from phenylalanine: independent existence in caudate nucleus synaptosomes.
Topics: Animals; Caudate Nucleus; Dihydroxyphenylalanine; Dopamine; Female; In Vitro Techniques; Phenylalanine; Rats; Synaptosomes; Tyrosine | 1977 |
Enhancement of the biological value of whey protein by covalent addition into peptide linkage of limiting essential amino acids.
Topics: Amino Acids, Essential; Animals; Dietary Proteins; Evaluation Studies as Topic; Isoleucine; Methionine; Milk Proteins; Peptides; Phenylalanine; Rats; Tyrosine | 1977 |
Correlation of the plasma tyrosine to phenylalanine ratio with energy intake in self-selecting weanling rats.
Topics: Amino Acids; Animals; Dietary Proteins; Feeding Behavior; Glutens; Kinetics; Male; Phenylalanine; Rats; Tyrosine | 1977 |
Rapid quantitative determination of plasma phenylalanine and tyrosine by automated ion-exchange chromatography using an internal standard.
Topics: Autoanalysis; Chromatography, Ion Exchange; Humans; Phenylalanine; Tyrosine | 1976 |
Dopaminergic neurons: effects of electrical stimulation on dopamine biosynthesis.
Topics: Animals; Corpus Striatum; Dopamine; Electric Stimulation; Kinetics; Male; Neurons; Olfactory Pathways; Phenylalanine; Rats; Substantia Nigra; Tyrosine | 1976 |
American Academy of Pediatrics. Committee on Nutrition: special diets for infants with inborn errors of amino acid metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cysteine; Histidine; Homocystinuria; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Nutritional Requirements; Phenylalanine; Phenylketonurias; Risk; Tyrosine; Valine | 1976 |
Metabolism of L-(U-14C)valine, L-(U-14C)leucine, L-(U-14C)histidine and L-(U-14C) phenylalanine by the isolated perfused lactating guinea-pig mammary gland.
Topics: Amino Acids, Essential; Animals; Caseins; Female; Glutamates; Guinea Pigs; Histidine; In Vitro Techniques; Lactation; Leucine; Mammary Glands, Animal; Perfusion; Phenylalanine; Pregnancy; Tyrosine; Valine | 1976 |
[Specificity of thermolysin action on dog myoglobin].
Topics: Amino Acid Sequence; Animals; Binding Sites; Dipeptides; Dogs; Isoleucine; Myoglobin; Peptide Fragments; Phenylalanine; Protein Binding; Structure-Activity Relationship; Thermolysin; Tyrosine | 1976 |
Hyperphenylalaninemias and tyrosinemias.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Humans; Infant; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1976 |
Phenylalanine hydroxylation and tyrosine requirement of cultured cells. Evidence of phenylalanine hydroxylation in mastocytoma cells in culture.
Topics: Cell Division; Cell Line; Cells, Cultured; Culture Media; HeLa Cells; Hydroxylation; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1976 |
Regional brain indoleamine metabolism following chronic portacaval anastomosis in the rat.
Topics: Animals; Brain; Disease Models, Animal; Fatty Acids; Histidine; Hydroxyindoleacetic Acid; Hypothalamus; Isoleucine; Leucine; Liver Cirrhosis; Phenylalanine; Portacaval Shunt, Surgical; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1976 |
Hemoglobin M equon beta 41 (C7) phenylalanine leads to tyrosine.
Topics: Adult; Amino Acids; Anemia, Hemolytic; Electrophoresis, Cellulose Acetate; Female; Hemoglobins, Abnormal; Humans; Methemoglobin; Oxygen Consumption; Peptides; Phenylalanine; Tyrosine; Wisconsin | 1976 |
Transfer RNA species in tumors of different growth rates.
Topics: Adenocarcinoma; Animals; Cell Division; Female; Histidine; Liver; Lymphoma; Lysine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Phenylalanine; RNA, Neoplasm; RNA, Transfer; Time Factors; Tyrosine | 1976 |
Lowering brain phenylalanine levels by giving other large neutral amino acids. A new experimental therapeutic approach to phenylketonuria.
Topics: Amino Acids; Animals; Brain Chemistry; Dose-Response Relationship, Drug; Drug Combinations; Humans; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1976 |
Preparation of selectively deuterated aromatic amino acids for use in 1H NMR studies of proteins.
Topics: Deuterium; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1976 |
Circular dichroism and difference spectra of members of the troponin-tropomyosin system in cetyltrimethylammonium bromide.
Topics: Cetrimonium Compounds; Circular Dichroism; Molecular Conformation; Muscle Proteins; Phenylalanine; Protein Binding; Protein Conformation; Quaternary Ammonium Compounds; Spectrophotometry, Ultraviolet; Tropomyosin; Troponin; Tryptophan; Tyrosine | 1976 |
Amino acid metabolism in Friedreich's ataxia.
Topics: Alanine; Amino Acids; Aminobutyrates; Asparagine; Aspartic Acid; Friedreich Ataxia; Glycine; Histidine; Humans; Isoleucine; Ornithine; Phenylalanine; Phosphatidylethanolamines; Sarcosine; Serine; Taurine; Tyrosine; Valine | 1976 |
Determination of deuterium-labeled phenylalanine and tyrosine in human plasma with high pressure liquid chromatography and mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Deuterium; Humans; Isotope Labeling; Mass Spectrometry; Phenylalanine; Phenylthiohydantoin; Tyrosine | 1976 |
Monoamine metabolism in the isolated perfused rat brain.
Topics: Acetoacetates; Animals; Brain; Dopamine; Glucose; Male; Norepinephrine; Perfusion; Phenylalanine; Rats; Serotonin; Tranylcypromine; Tryptophan; Tyrosine | 1976 |
Biopterin derivatives in normal and phenylketonuric patients after oral loads of L-phenylalanine, L-tyrosine, and L-tryptophan.
Topics: Administration, Oral; Adolescent; Adult; Biopterins; Child, Preschool; Chromatography, Thin Layer; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Pteridines; Tryptophan; Tyrosine | 1976 |
Results of loading doses of aspartame by two phenylketonuric (PKU) children compared with two normal children.
Topics: Adolescent; Aspartame; Child; Dipeptides; Female; Glutamine; Humans; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1976 |
Liver phenylalanine hydroxylase assay.
Topics: Animals; Colorimetry; Guinea Pigs; Humans; Liver; Methods; Mice; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Tyrosine | 1976 |
The isolation, properties, and assay of phenylalanine hydroxylase from human and rat liver.
Topics: Adult; Animals; Humans; Infant, Newborn; Liver; Molecular Weight; Phenylalanine; Phenylalanine Hydroxylase; Rats; Surface-Active Agents; Tyrosine | 1976 |
Amino acid composition, distribution and origin of "tuft" protein in human and bovine dental enamel.
Topics: Alanine; Amelogenesis; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Dental Enamel; Dental Enamel Proteins; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Sidechain torsional potentials and motion of amino acids in porteins: bovine pancreatic trypsin inhibitor.
Topics: Animals; Cattle; Magnetic Resonance Spectroscopy; Mathematics; Pancreas; Phenylalanine; Protein Conformation; Trypsin Inhibitors; Tyrosine; X-Ray Diffraction | 1975 |
Acute reduction of brain serotonin and 5-HIAA following food consumption: correlation with the ratio of serum tryptophan to the sum of competing amino acids.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Diet; Hydroxyindoleacetic Acid; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1975 |
Evidence that monoamines influence human evoked potentials.
Topics: 5-Hydroxytryptophan; Adolescent; Biogenic Amines; Dihydroxyphenylalanine; Evoked Potentials; Female; Humans; Male; Phenylalanine; Phenylketonurias; Reaction Time; Tyrosine; Visual Cortex; Visual Perception | 1975 |
Dynamics of the aromatic amino acid residues in the globular conformation of the basic pancreatic trypsin inhibitor (BPTI). II. Semi-empirical energy calculations.
Topics: Amino Acids; Aprotinin; Magnetic Resonance Spectroscopy; Models, Chemical; Phenylalanine; Protein Conformation; Tyrosine | 1976 |
Radiation-induced binding of some protein and nucleic acid constituents with macromolecular components in cell systems.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Cell Line; Cobalt Radioisotopes; Cysteine; Cystine; Cytosine; Dose-Response Relationship, Radiation; Escherichia coli; Gamma Rays; Histidine; Leukemia, Lymphoid; Macromolecular Substances; Methionine; Mice; Phenylalanine; Protein Binding; Purines; Pyrimidines; Radiation Effects; Sulfur Radioisotopes; Thymine; Tritium; Tryptophan; Tyrosine; Uracil | 1975 |
Equivalent and non-equivalent binding sites for tRNA on aminoacyl-tRNA synthetases.
Topics: Amino Acyl-tRNA Synthetases; Escherichia coli; Kinetics; Macromolecular Substances; Magnesium; Mathematics; Molecular Weight; Phenylalanine; Phenylalanine-tRNA Ligase; Protein Binding; RNA, Transfer; Saccharomyces cerevisiae; Serine; Serine-tRNA Ligase; Spectrophotometry, Ultraviolet; Tyrosine; Tyrosine-tRNA Ligase | 1975 |
B-chain shortening of matrix-bound insulin with pepsin, II. Preparation and properties of camel des-pentapeptide (B26-30)- and des-PheB1-des-pentapeptide (B26-30)- insulin.
Topics: Amino Acids; Animals; Binding Sites; Camelus; Crystallization; Insulin; Oligopeptides; Pepsin A; Phenylalanine; Protein Binding; Tyrosine | 1975 |
Mutations affecting aromatic amino acid transport in Escherichia coli and Salmonella typhimurium.
Topics: Alanine; Amino Acids; Biological Transport, Active; Chromosome Mapping; Escherichia coli; Ethidium; Genes; Glycine; Mutation; Phenylalanine; Plasmids; Salmonella typhimurium; Tryptophan; Tyrosine | 1975 |
Radiation-induced binding of OH-substituted aromatic amino acids, tyrosine and dopa, mutually and with albumin in aqueous solution.
Topics: Carbon Radioisotopes; Chromatography, Paper; Cobalt Radioisotopes; Dihydroxyphenylalanine; Dose-Response Relationship, Radiation; Gamma Rays; Phenylalanine; Protein Binding; Radiation Effects; Serum Albumin, Bovine; Solutions; Tyrosine; Water | 1975 |
Detection of heterozygotes for phenylketonuria and hyperphenylaianinemia by gas-chromatographic analysis of aromatic acid excretion in urine.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, Gas; Female; Heterozygote; Humans; Male; Methods; Phenylalanine; Phenylketonurias; Tyrosine | 1975 |
The use of 13C nuclear magnetic resonance of aromatic amino acid residues to determine the midpoint oxidation-reduction potential of each iron-sulfur cluster of Clostridium acidi-urici and Clostridium pasteurianum ferredoxins.
Topics: Carbon Isotopes; Clostridium; Ferredoxins; Iron; Magnetic Resonance Spectroscopy; Mathematics; Oxidation-Reduction; Phenylalanine; Potentiometry; Protein Conformation; Sulfur; Tyrosine | 1975 |
Biosynthesis of phenylalanine, tyrosine, 3-(3-carbocyphenyl) alanine and 3-(3-carbocy-4-hydroxyphenyl) alanine in higher plants. Examples of the transformation possibilities for chorismic acid.
Topics: Amino Acids; Benzoates; Carbon Radioisotopes; Cyclohexanecarboxylic Acids; Hydroxy Acids; Models, Chemical; Phenylalanine; Plants; Shikimic Acid; Species Specificity; Tritium; Tyrosine; Vinyl Compounds | 1975 |
Biosynthesis of p-aminophenylalanine: part of a general scheme for the biosynthesis of chorisimic acid derivatives.
Topics: Amines; Carbon Radioisotopes; Cyclohexanecarboxylic Acids; Models, Chemical; Phenylalanine; Phenylpyruvic Acids; Plants; Pyruvates; Shikimic Acid; Tyrosine; Vinyl Compounds | 1975 |
Chorismate mutase of Chlamydomonas reinhardi. Partial purification and some properties.
Topics: Chlamydomonas; Chorismate Mutase; Chromatography, DEAE-Cellulose; Chromatography, Gel; Dihydroxyphenylalanine; Isomerases; Kinetics; Molecular Weight; Phenylalanine; Species Specificity; Tryptophan; Tyrosine | 1975 |
Gas-liquid chromatography of phenylalanine and its metabolites in serum and urine of various hyperphenylalaninemic subjects, their relatives, and controls.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Heterozygote; Humans; Infant; Lactates; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1975 |
Biosynthesis of gliotoxin and mycelianamide.
Topics: Alanine; Biological Transport; Dipeptides; Penicillium; Phenylalanine; Piperazines; Tyrosine | 1975 |
Classic phenylketonuria: diagnosis through heterozygote detection.
Topics: Adolescent; Adult; Chromatography, Ion Exchange; Consanguinity; Female; Genetic Counseling; Genotype; Heterozygote; Homozygote; Humans; Intellectual Disability; Male; Phenotype; Phenylalanine; Phenylketonurias; Statistics as Topic; Tyrosine | 1975 |
An improved technique for the analysis of amino acids and related compounds on thin layers of cellulose. X. The characterization of some methionyl, phenylalanyl, tyrosyl and other peptides by thin-layer and ion-exchange chromatography.
Topics: Amino Acids; Aspartic Acid; Chromatography; Chromatography, Ion Exchange; Chromatography, Thin Layer; Densitometry; Dipeptides; Glutamates; Methionine; Methods; Peptides; Phenylalanine; Serine; Solvents; Tyrosine | 1975 |
Intermittent alcaptonuria.
Topics: Alkaptonuria; Child; Homogentisic Acid; Humans; Male; Oxygenases; Phenylalanine; Tyrosine | 1975 |
Ligand-exchange chromatography of amino acids on copper-, cobalt- and zinc-chelex 100.
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Cobalt; Copper; Cysteine; Glutamates; Histidine; Ion Exchange Resins; Ligands; Lysine; Phenylalanine; Quaternary Ammonium Compounds; Serine; Threonine; Tyrosine; Zinc | 1975 |
Synthesis by conventional methods of human growth hormone peptide fragments. I.
Topics: Alanine; Asparagine; Aspartic Acid; Glutamine; Growth Hormone; Histidine; Humans; Leucine; Lysine; Optical Rotation; Peptides; Phenylalanine; Serine; Threonine; Tyrosine | 1975 |
Kinetic analysis of phenylalanine-induced inhibition in the saturable influx of tyrosine, tryptophan, leucine and histidine into brain cortex slices from adult and 7-day-old rats.
Topics: Animals; Animals, Newborn; Biological Transport, Active; Cerebral Cortex; Histidine; In Vitro Techniques; Kinetics; Leucine; Male; Phenylalanine; Rats; Tryptophan; Tyrosine | 1975 |
Human liver alanine aminopeptidase. Inhibition by amino acids.
Topics: Alanine; Alanine Transaminase; Amino Acids; Aminopeptidases; Chromatography, DEAE-Cellulose; Chromatography, Gel; Humans; Kinetics; Leucine; Liver; Methionine; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1975 |
Application of nuclear magnetic resonance spectroscopy to proteins.
Topics: Animals; Binding Sites; Calcium; Cattle; Gadolinium; Histidine; Kinetics; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Neurophysins; Oxytocin; Pancreas; Phenylalanine; Protein Binding; Ribonucleases; Structure-Activity Relationship; Temperature; Thymine Nucleotides; Tyrosine; Vasopressins; X-Ray Diffraction | 1975 |
The phenylalanine and tyrosine contnet of maternal and fetal body fluids from rabbits fed aspartame.
Topics: Amino Acids; Amniotic Fluid; Animals; Aspartame; Body Fluids; Body Weight; Dipeptides; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Rabbits; Tyrosine | 1975 |
Aromatic amino acid biosynthesis in Alcaligenes eutrophus H16. II. The isolation and characterization of mutants auxotrophic for phenylalanine and tyrosine.
Topics: Alcaligenes; Amino Acids; Chorismic Acid; Chromatography, DEAE-Cellulose; Culture Media; Cyclohexanecarboxylic Acids; Mutagens; Mutation; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Pyruvates; Tyrosine | 1975 |
Phenylalanine hydroxylase from Pseudomonas sp. (ATCC 11299a). Purification, molecular weight, and influence of tyrosine metabolites on activation and hydroxylation.
Topics: Enzyme Activation; Homogentisic Acid; Iron; Kinetics; Molecular Weight; Phenylacetates; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pseudomonas; Tyrosine | 1975 |
Prospects for a pharmacological treatment of phenylketonuria.
Topics: Anabolic Agents; Child; Child, Preschool; Female; Humans; Male; Phenylalanine; Phenylketonurias; Stanozolol; Tyrosine | 1975 |
On the preparation of 1-[2, 3-H2] phenylalaine and 1-[2,3-H2]Tyrosine.
Topics: Isotope Labeling; Phenylalanine; Tritium; Tyrosine | 1975 |
[The metabolism of C14-labeled phenylalanine and tyrosine in malaria-infected Culex females (author's transl)].
Topics: Animals; Autoradiography; Carbon Radioisotopes; Cell-Free System; Chromatography; Culex; Female; Malaria; Phenylalanine; Rats; Time Factors; Tyrosine | 1975 |
Amino acid reabsorption in the rat nephron. Free flow micropuncture study.
Topics: Absorption; Alanine; Amino Acids; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Glutamates; Glycine; Isoleucine; Kidney; Kidney Tubules, Proximal; Leucine; Lysine; Male; Nephrons; Phenylalanine; Proline; Rats; Taurine; Tyrosine | 1975 |
Permanent chemical phenylketonuria and a normal phenylalanine tolerance in two sisters with a normal mental development.
Topics: Adolescent; Adult; Benzoates; Child; Creatinine; Female; Humans; Lactates; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1975 |
Effect of aromatic acids on protein synthesis in subcellular preparations from the rat brain.
Topics: Animals; Benzoates; Brain; Cell-Free System; Depression, Chemical; Homogentisic Acid; In Vitro Techniques; Nerve Tissue Proteins; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rats; Salicylates; Transfer RNA Aminoacylation; Tryptophan; Tyrosine | 1975 |
Studies on the inhibition of synthesis of the tyrosine-rich proteins of wool.
Topics: Amino Acids; Animals; Depression, Chemical; Dexamethasone; Diet; Male; Methionine; Mimosine; Phenylalanine; Protein Biosynthesis; Pyridones; Sheep; Sulfur; Tyrosine; Wool | 1975 |
The reciprocal exclusion by L-dopa (L-3,4-dihydroxyphenylalanine) and L-tyrosine of their incorporation as single units into a soluble rat brain protein.
Topics: Adenosine Triphosphate; Animals; Brain; Dihydroxyphenylalanine; Kinetics; Magnesium; Nerve Tissue Proteins; Osmolar Concentration; Phenylalanine; Potassium Chloride; Rats; Tyrosine | 1975 |
Fluorotyrosine alkaline phosphatase: internal mobility of individual tyrosines and the role of chemical shift anisotropy as a 19F nuclear spin relaxation mechanism in proteins.
Topics: Alkaline Phosphatase; Binding Sites; Magnetic Resonance Spectroscopy; Mathematics; Molecular Weight; Phenylalanine; Protein Binding; Protein Conformation; Tyrosine | 1975 |
Some biochemical effects of chloral hydrate in an infant with a tyrosinemia-like syndrome.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Ascorbic Acid; Chloral Hydrate; Female; Humans; Hydrocephalus; Infant; Lactates; Methionine; Oxygenases; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Syndrome; Tyrosine | 1975 |
Determination of phenylalanine hydroxylase activity in patients with phenylketonuria and hyperphenylalaninemia.
Topics: Adolescent; Adult; Aged; Biopterins; Child; Child, Preschool; Female; Humans; Infant; Liver; Lysophosphatidylcholines; Male; Middle Aged; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1975 |
Free amino acids in plasma and erythrocytes during and after cardiopulmonary by-pass in open-heart surgery.
Topics: Amino Acids; Amino Acids, Essential; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Erythrocytes; Extracorporeal Circulation; Humans; Phenylalanine; Tyrosine | 1975 |
Urinary phenolic acid and alcohol excretion in the newborn.
Topics: Alcohols; Amino Acid Metabolism, Inborn Errors; Bilirubin; Birth Weight; Catecholamines; Creatinine; Dopamine; Epinephrine; Female; Gestational Age; Homovanillic Acid; Humans; Infant, Newborn; Infant, Premature; Jaundice, Neonatal; Male; Norepinephrine; Phenols; Phenylalanine; Tyrosine; Vanilmandelic Acid | 1975 |
Incorporation of L-tyrosine, L-phenylalanine and L-3,4-dihydroxyphenylalanine as single units into rat brain tubulin.
Topics: Animals; Brain; Colchicine; Dihydroxyphenylalanine; Glycoproteins; Phenylalanine; Rats; Receptors, Drug; Tubulin; Tyrosine | 1975 |
Studies on the experimental phenylketonuria in rats.
Topics: Amino Acids; Animals; Brain Chemistry; Female; Homogentisic Acid; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Rats; Transaminases; Tyrosine | 1975 |
[The relationship between hyperphenylalaninemia and mental retardation].
Topics: Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Male; Mental Disorders; Phenylacetates; Phenylalanine; Phenylketonurias; Tyrosine | 1975 |
Amino acid biosynthesis in mixed rumen cultures.
Topics: Alanine; Amino Acids; Animals; Bacteria; Cattle; Citric Acid Cycle; Female; Fumarates; Isoleucine; Ketoglutaric Acids; Leucine; Lysine; Oxaloacetates; Oxidation-Reduction; Phenylalanine; Propionates; Pyruvates; Rumen; Serine; Tyrosine; Valine | 1975 |
[Free amino acids in the amniotic fluid and in maternal blood in advanced pregnancy].
Topics: Alanine; Amino Acids; Amniotic Fluid; Cysteine; Female; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proline; Serine; Threonine; Tyrosine; Valine | 1975 |
Heterozygote detection in phenylketonuria. Measurement of discriminatory ability and interpretation of the phenylalanine loading test by determination of the heterozygote likelihood ratio.
Topics: Heterozygote; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1975 |
Effects of intravenous infusion of mimosine on wool growth of Merino sheep.
Topics: Animals; Cystine; Depression, Chemical; Infusions, Parenteral; Male; Mimosine; Phenylalanine; Pyridones; Sheep; Tyrosine; Wool | 1975 |
Magnetic enzyme membranes as active elements of electrochemical sensors: specific amino acid enzyme elctrodes.
Topics: Amino Acids; Carbon Dioxide; Carboxy-Lyases; Electrochemistry; Electrodes; Enzymes; Lysine; Magnetics; Membranes, Artificial; Models, Chemical; Phenylalanine; Tyrosine | 1975 |
[Multiple screening tests for hereditary metabolic diseases. Clinical problems and questions of interpretation].
Topics: Genotype; Histidine; Humans; Metabolism, Inborn Errors; Methods; Phenylalanine; Tyrosine | 1975 |
[Growth and sexual reproduction of the dermatophyte Arthroderma vanbreuseghemii Takashio (Trichophyton mentagrophytes (Robin blanchard) on a synthetic medium].
Topics: Amino Acids; Ascomycota; Aspartic Acid; Conjugation, Genetic; Culture Media; Glucose; Glutamates; Phenylalanine; Serine; Shikimic Acid; Tryptophan; Tyrosine | 1975 |
[Effects of beta-phenylethylamine derivatives on the central nervous system. (5) Changes in the volume of spontaneous movement in mice with intracerebral administration of tyramine].
Topics: Animals; Brain; Brain Chemistry; Dopamine; Isocarboxazid; Male; Mice; Motor Activity; Norepinephrine; Phenylalanine; Serotonin; Tyramine; Tyrosine | 1975 |
On the preparation of 80Br- or 82Br-biomolecules via excitation labelling methods.
Topics: Bromine; Deoxycytidine; Deoxyuridine; Guanosine; Isotope Labeling; Phenylalanine; Radioisotopes; Tyrosine | 1976 |
Behavioral and biochemical correlates of diet change in phenylketonuria.
Topics: Adolescent; Child; Child Behavior; Child, Institutionalized; Diet; Discrimination, Psychological; Female; Humans; Male; Phenothiazines; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1976 |
Some biological properties and an in vivo evaluation of tyrosine phenol-lyase on growth of B-16 melanoma.
Topics: Animals; Female; Lactate dehydrogenase-elevating virus; Lyases; Male; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine; Tyrosine Phenol-Lyase | 1976 |
Synthesis of peptides by fragment condensation on a solid support. II. A scheme for preparation of 4,8-disubstituted vasopressins evaluated on 8-arginine-vasopressin.
Topics: Arginine Vasopressin; Asparagine; Cysteine; Peptide Fragments; Peptides; Phenylalanine; Proline; Tyrosine; Vasopressins | 1976 |
Efficiency of phenylpyruvic and phenyllactic acids as substitutes for phenylalanine in the diet of the growing rat.
Topics: Animals; Benzene Derivatives; Body Weight; Cinnamates; Diet; Dose-Response Relationship, Drug; Growth; Lactates; Male; Nutritional Requirements; Phenylalanine; Phenylpyruvic Acids; Pyridoxine; Rats; Stereoisomerism; Tyrosine | 1976 |
Hereditary tyrosinaemia. Clinical, enzymatic, and pathological study of an infant with the acute form of the disease.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Humans; Kidney; Liver; Male; Methionine; Pancreas; Phenylalanine; Tyrosine | 1976 |
Influence of basic polypeptides on the phase transition of phospholipid liposomes.
Topics: Binding Sites; Calorimetry; Kinetics; Liposomes; Lysine; Models, Biological; Peptides; Phenylalanine; Phosphatidylcholines; Phosphatidylserines; Phospholipids; Thermodynamics; Tyrosine | 1976 |
In vivo effects of phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Animals; Half-Life; Leukemia, Experimental; Mice; Neoplasms, Experimental; Phenylalanine; Phenylalanine Ammonia-Lyase; Tyrosine | 1976 |
Effect of cotrimoxazole on the response to phenylalanine loading in man.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Drug Combinations; Female; Glomerular Filtration Rate; Heterozygote; Humans; Kidney; Male; Middle Aged; Phenylalanine; Phenylketonurias; Sulfamethoxazole; Time Factors; Trimethoprim; Tyrosine; Urine | 1976 |
Regulation of L-phenylalanine ammonia-lyase from Rhizoctonia solani.
Topics: Ammonia-Lyases; Cell-Free System; Cycloheximide; Dactinomycin; Enzyme Induction; Enzyme Repression; Glucose; Light; Mitosporic Fungi; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Growth Regulators; Rhizoctonia; Stereoisomerism; Temperature; Tryptophan; Tyrosine | 1976 |
Purification and properties of chorismate mutase-prephenate dehydratase and prephenate dehydrogenase from Alcaligenes eutrophus.
Topics: Alcaligenes; Ammonium Sulfate; Cell-Free System; Chemical Fractionation; Chorismate Mutase; Chromatography; Hydro-Lyases; Isomerases; Metals; Molecular Weight; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Prephenate Dehydratase; Prephenate Dehydrogenase; Sulfhydryl Reagents; Tyrosine | 1976 |
The aromatic residue content of the enzyme rhodanese.
Topics: Animals; Binding Sites; Cattle; Guanidines; Liver; Molecular Weight; Phenylalanine; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Sulfurtransferases; Thiosulfate Sulfurtransferase; Tryptophan; Tyrosine | 1976 |
Decarboxylation of newly formed DOPA by caudate nucleus synaptosomal particles.
Topics: Animals; Caudate Nucleus; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Female; Phenylalanine; Rats; Synaptosomes; Tyrosine | 1976 |
Surface topography of the Bacillus stearothermophilus ribosome.
Topics: Electrophoresis, Polyacrylamide Gel; Geobacillus stearothermophilus; Molecular Conformation; Phenylalanine; Poly U; Ribosomal Proteins; Ribosomes; Tyrosine | 1976 |
The end products of the metabolism of aromatic amino acids by Clostridia.
Topics: Amino Acids; Clostridium; Indoleacetic Acids; Indoles; Phenols; Phenylacetates; Phenylalanine; Tryptophan; Tyrosine | 1976 |
Mutational analysis of Agrobacterium tumefaciens virD2: tyrosine 29 is essential for endonuclease activity.
Topics: Agrobacterium tumefaciens; Base Sequence; Binding Sites; DNA Damage; DNA Mutational Analysis; Endonucleases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Tyrosine | 1992 |
Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line; Cloning, Molecular; Cysteine; DNA; Drug Resistance; Kinetics; Molecular Sequence Data; Mutation; Ouabain; Phenylalanine; Polymerase Chain Reaction; Sequence Alignment; Sodium-Potassium-Exchanging ATPase; Tyrosine; Xenopus laevis | 1992 |
The hydroxylation of phenylalanine and tyrosine: a comparison with salicylate and tryptophan.
Topics: Chelating Agents; Dihydroxyphenylalanine; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Iron; Kinetics; Macromolecular Substances; Oxidation-Reduction; Phenylalanine; Pulse Radiolysis; Salicylates; Salicylic Acid; Tryptophan; Tyrosine | 1992 |
Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function.
Topics: Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cloning, Molecular; Cricetinae; Exons; Genetic Vectors; Homeostasis; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Mapping; Phenylalanine; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Transfection; Tyrosine | 1992 |
A highly conserved tyrosine residue at codon 845 within the kinase domain is not required for the transforming activity of human epidermal growth factor receptor.
Topics: 3T3 Cells; Animals; Base Sequence; Codon; DNA Replication; Drug Resistance; Epidermal Growth Factor; ErbB Receptors; Gentamicins; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Protein-Tyrosine Kinases; Transfection; Tyrosine | 1992 |
Analogs of the delta opioid receptor selective cyclic peptide [2-D-penicillamine,5-D-penicillamine]-enkephalin: 2',6'-dimethyltyrosine and Gly3-Phe4 amide bond isostere substitutions.
Topics: Amides; Amino Acid Sequence; Analgesics; Animals; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Glycine; Male; Mice; Molecular Sequence Data; Muscle Contraction; Neuroblastoma; Peptides, Cyclic; Phenylalanine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Structure-Activity Relationship; Substrate Specificity; Tumor Cells, Cultured; Tyrosine; Vas Deferens | 1992 |
Incorporation of a novel conformationally restricted tyrosine analog into a cyclic, delta opioid receptor selective tetrapeptide (JOM-13) enhances delta receptor binding affinity and selectivity.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Brain; Guinea Pigs; Molecular Sequence Data; Oligopeptides; Phenylalanine; Receptors, Opioid; Structure-Activity Relationship; Tyrosine | 1992 |
[A rare cause of neonatal hyperphenylalaninemia: tyrosinemia type I].
Topics: Amino Acid Metabolism, Inborn Errors; Female; Humans; Infant, Newborn; Phenylalanine; Tyrosine | 1992 |
[The metabolic basis of the hyperphenylalaninemias and tyrosinemia].
Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; DNA; Humans; Hydrolases; Phenylalanine; Phenylalanine Hydroxylase; Polymorphism, Restriction Fragment Length; Tyrosine; Tyrosine Transaminase | 1992 |
Molecular basis for nonphenylketonuria hyperphenylalaninemia.
Topics: Base Sequence; Exons; Female; Haplotypes; Humans; Infant, Newborn; Male; Metabolism, Inborn Errors; Molecular Sequence Data; Oligonucleotide Probes; Pedigree; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Tyrosine | 1992 |
The A14 position of insulin tolerates considerable structural alterations with modest effects on the biological behavior of the hormone.
Topics: Adipose Tissue; Alanine; Amino Acids; Animals; Cattle; Cycloleucine; Glucose; Glutamates; Glutamic Acid; Histidine; Insulin; Lipids; Liver; Lysine; Phenylalanine; Rats; Receptor, Insulin; Sheep; Structure-Activity Relationship; Swine; Tyrosine | 1992 |
Genetic breeding of L-tyrosine producer from Brevibacterium lactofermentum.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Amino Acids; Brevibacterium; Drug Resistance, Microbial; Kinetics; Mutation; Phenotype; Phenylalanine; Tyrosine | 1990 |
Detection of proteins and phenol in DNA samples with second-derivative absorption spectroscopy.
Topics: Animals; DNA; Humans; Phenol; Phenols; Phenylalanine; Proteins; RNA; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1992 |
Replacement of Tyr-SO3H by a p-carboxymethyl-phenylalanine in a CCK8-derivative preserves its high affinity for CCK-B receptor.
Topics: Amino Acid Sequence; Amylases; Animals; Binding Sites; Biological Assay; Brain; Guinea Pigs; Molecular Sequence Data; Pancreas; Phenylalanine; Receptors, Cholecystokinin; Sincalide; Tyrosine | 1992 |
Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Acetoacetates; alpha-Fetoproteins; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child; Child, Preschool; Cyclohexanones; Erythrocytes; Heptanoates; Humans; Hydroxybenzoates; Infant; Kidney Tubules; Liver; Nitrobenzoates; Phenylalanine; Phosphates; Porphobilinogen Synthase; Proteinuria; Tyrosine | 1992 |
Effects of aging and dietary restriction on tissue protein synthesis: relationship to plasma insulin-like growth factor-1.
Topics: Aging; Animals; Diaphragm; Diet; Insulin-Like Growth Factor I; Liver; Male; Mice; Mice, Inbred C57BL; Myocardium; Phenylalanine; Protein Biosynthesis; Specific Pathogen-Free Organisms; Time Factors; Tissue Distribution; Tyrosine | 1992 |
Allosteric properties of haemoglobin beta 41 (C7) Phe-->Tyr: a stable, low-oxygen-affinity variant synthesized in Escherichia coli.
Topics: Allosteric Site; Blood Substitutes; Carbon Monoxide; Cloning, Molecular; Escherichia coli; Hemoglobins; Humans; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Substrate Specificity; Tyrosine | 1992 |
Site-specific cleavage of glycated human serum albumin in the presence of iron.
Topics: Humans; In Vitro Techniques; Iron; Phenylalanine; Serum Albumin; Tyrosine | 1992 |
Determination and assessment of the stability of phenylalanine and tyrosine in blood spots by HPLC.
Topics: Chromatography, High Pressure Liquid; Drug Stability; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Tyrosine | 1992 |
[Imbalance of amino acid metabolism in fulminant hepatitis and its management].
Topics: Amino Acids, Branched-Chain; Glucagon; Hepatic Encephalopathy; Hepatitis; Humans; Insulin; Methionine; Phenylalanine; Tyrosine | 1992 |
Parallel control of hepatic proteolysis by phenylalanine and phenylpyruvate through independent inhibitory sites at the plasma membrane.
Topics: Animals; Cell Membrane; Liver; Phenylalanine; Phenylpyruvic Acids; Proteins; Rats; Rats, Inbred Lew; Tyrosine | 1992 |
Development and validation of a robust specific enzyme mediated assay for phenylalanine in serum.
Topics: Amino Acid Oxidoreductases; Chromatography, High Pressure Liquid; Clinical Enzyme Tests; Colorimetry; Humans; Hydrogen-Ion Concentration; Kinetics; NAD; Phenylalanine; Reproducibility of Results; Tetrazolium Salts; Tyrosine | 1992 |
Late diagnosis of phenylketonuria in a Bedouin mother.
Topics: Abortion, Habitual; Adult; Child, Preschool; Female; Fetal Diseases; Heart Defects, Congenital; Humans; Infant; Intellectual Disability; Male; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1992 |
Phenylalanine and tyrosine kinetics in relation to altered protein and phenylalanine and tyrosine intakes in healthy young men.
Topics: Adult; Amino Acids, Essential; Carbon Dioxide; Fasting; Humans; Hydroxylation; Kinetics; Leucine; Male; Nitrogen; Oxidation-Reduction; Phenylalanine; Pilot Projects; Tyrosine | 1992 |
A conditional secretory mutant in an Ig L chain is caused by replacement of tyrosine/phenylalanine 87 with histidine.
Topics: Base Sequence; Histidine; Immunoglobulin kappa-Chains; In Vitro Techniques; Macromolecular Substances; Molecular Sequence Data; Mutation; Oligodeoxyribonucleotides; Phenylalanine; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tumor Cells, Cultured; Tyrosine | 1992 |
The multiple-minima problem in small peptides revisited. The Threshold Accepting approach.
Topics: Algorithms; Computer Simulation; Glycine; Leucine; Methionine; Oligopeptides; Phenylalanine; Protein Conformation; Tyrosine | 1992 |
Reciprocal effects between opioid peptides and human polymorphonuclear leukocytes--I. Chemical modifications of Leu-enkephalin by phorbol myristate acetate-stimulated polymorphonuclear leukocytes.
Topics: Chromatography, High Pressure Liquid; Endorphins; Enkephalin, Leucine; Humans; Hydroxylation; Luminescent Measurements; Mass Spectrometry; Neutrophils; Peptides; Phenylalanine; Tetradecanoylphorbol Acetate; Tyrosine | 1992 |
The aromatic binding site for tetraethylammonium ion on potassium channels.
Topics: Animals; Binding Sites; DNA Mutational Analysis; Drosophila melanogaster; Electric Conductivity; In Vitro Techniques; Ion Channel Gating; Membrane Potentials; Phenylalanine; Potassium Channels; Recombinant Proteins; Tetraethylammonium Compounds; Thermodynamics; Tyrosine | 1992 |
Plasma concentrations and pharmacokinetics of phenylalanine in rats and mice administered aspartame.
Topics: Administration, Oral; Amino Acids; Animals; Aspartame; Humans; Male; Mice; Mice, Inbred ICR; Phenylalanine; Random Allocation; Rats; Rats, Inbred Strains; Tyrosine | 1992 |
Newborn screening for phenylketonuria: thirty years of progress.
Topics: Adolescent; Adult; Child; Diagnosis, Differential; Female; Follow-Up Studies; Humans; Infant, Newborn; Intelligence Tests; Neonatal Screening; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pterins; Tyrosine | 1992 |
Changes in brain monoamine metabolism in rats with acute ischemic hepatic failure under artificial cardiopulmonary management.
Topics: Animals; Brain; Dopamine; Hepatic Encephalopathy; Ischemia; Liver; Liver Diseases; Male; Norepinephrine; Phenylalanine; Rats; Rats, Inbred Strains; Respiration, Artificial; Serotonin; Tyrosine | 1992 |
Engineering of the iron site in ribonucleotide reductase to a self-hydroxylating monooxygenase.
Topics: Base Sequence; Electrophoresis, Polyacrylamide Gel; Hydroxylation; Iron; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygenases; Phenylalanine; Protein Engineering; Ribonucleotide Reductases; Spectrum Analysis, Raman; Tyrosine | 1992 |
Prolactin responses to phenylalanine and tyrosine in phenylketonuria.
Topics: Adolescent; Adult; Female; Humans; Male; Phenylalanine; Phenylketonurias; Prolactin; Reference Values; Tyrosine | 1992 |
Defective biliary excretion of epinephrine metabolites in mutant (TR-) rats: relation to the pathogenesis of black liver in the Dubin-Johnson syndrome and Corriedale sheep with an analogous excretory defect.
Topics: Animals; Anions; Bile; Epinephrine; Female; Food, Formulated; Humans; Jaundice, Chronic Idiopathic; Liver; Lysosomes; Male; Metanephrine; Mutation; Phenylalanine; Pigmentation; Pigments, Biological; Rats; Rats, Mutant Strains; Sheep; Tryptophan; Tyrosine | 1992 |
Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
Topics: Animals; Antigen-Antibody Complex; Base Sequence; CHO Cells; Cricetinae; Deoxyglucose; DNA; Endocytosis; Enzyme Activation; Growth Substances; Immunoblotting; Insulin; Lectins; Molecular Sequence Data; Mutation; Phenylalanine; Phosphorylation; Precipitin Tests; Protein Kinases; Receptor, Insulin; Solubility; Thymidine; Transfection; Tyrosine | 1992 |
[Restoration of the potential-dependent L-phenylalanine-inhibited calcium current by L-tyrosine in cultured hippocampal neurons].
Topics: Animals; Biological Transport; Calcium Channels; Cells, Cultured; Hippocampus; Membrane Potentials; Neurons; Phenylalanine; Rats; Tyrosine | 1991 |
Effects of intracellular administration of L-tyrosine and L-phenylalanine on voltage-operated calcium conductance in PC12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; alpha-Methyltyrosine; Animals; Calcium Channels; Cell Line; Kinetics; Methyltyrosines; Phenylalanine; Pheochromocytoma; Potassium Channels; Rats; Tyrosine | 1991 |
Multiple forms of statherin in human salivary secretions.
Topics: Adsorption; Amino Acid Sequence; Amino Acids; Chromatography, Gel; Chromatography, High Pressure Liquid; Durapatite; Humans; Hydroxyapatites; Molecular Sequence Data; Phenylalanine; Phosphoserine; Salivary Proteins and Peptides; Spectrometry, Mass, Fast Atom Bombardment; Tyrosine | 1991 |
[Effect of intracellular administration of L-tyrosine and L-phenylalanine on voltage dependent calcium current in PC 12 pheochromocytoma cells].
Topics: Adenosine Diphosphate; Adrenal Gland Neoplasms; alpha-Methyltyrosine; Animals; Calcium Channels; Methyltyrosines; Phenylalanine; Pheochromocytoma; Rats; Tumor Cells, Cultured; Tyrosine; Tyrosine 3-Monooxygenase | 1991 |
Studies of the rate-limiting step in the tyrosine hydroxylase reaction: alternate substrates, solvent isotope effects, and transition-state analogues.
Topics: Adrenal Glands; Animals; Cattle; Kinetics; Phenylalanine; Protein Binding; Solvents; Substrate Specificity; Tyrosine; Tyrosine 3-Monooxygenase | 1991 |
No change in spontaneous behavior of rats after acute oral doses of aspartame, phenylalanine, and tyrosine.
Topics: Animals; Aspartame; Behavior, Animal; Central Nervous System; Data Interpretation, Statistical; Dextroamphetamine; Male; Motor Activity; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1991 |
Enhanced release of cholecystokinin in chickens fed diets high in phenylalanine or tyrosine.
Topics: Animals; Animals, Newborn; Chickens; Cholecystokinin; Crop, Avian; Dietary Proteins; Male; Phenylalanine; Tyrosine | 1991 |
[Regulation of the synthesis of 3-deoxy-D-arabinoheptuloso-7-phosphate-synthase in Pseudomonas bacteria].
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Phenylalanine; Pseudomonas; Species Specificity; Tyrosine | 1991 |
The hydroxylation of phenylalanine and tyrosine by tyrosine hydroxylase from cultured pheochromocytoma cells.
Topics: Animals; Biopterins; Catalysis; Dihydroxyphenylalanine; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Hydroxylation; Kinetics; Phenylalanine; Pheochromocytoma; Rats; Tumor Cells, Cultured; Tyrosine; Tyrosine 3-Monooxygenase | 1991 |
Use of high performance liquid chromatography in defining the abnormalities in the free amino acid patterns in the cerebrospinal fluid of patients with aseptic meningitis.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Chromatography, High Pressure Liquid; Female; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Glycine; Humans; Male; Meningitis, Aseptic; Middle Aged; Phenylalanine; Tyrosine | 1991 |
[The effect of copper on o- and m-tyrosine content in the serum of guinea pigs].
Topics: Animals; Ascorbic Acid; Brain; Copper; Guinea Pigs; Isomerism; Kidney; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1991 |
Analysis of mutant forms of the c-src gene product containing a phenylalanine substitution for tyrosine 416.
Topics: Animals; Annexins; Calcium-Binding Proteins; Cell Transformation, Neoplastic; Chick Embryo; Fibroblasts; Gene Expression; Genetic Variation; Immunoblotting; Mutation; Phenylalanine; Phosphopeptides; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Proto-Oncogenes; Tyrosine | 1990 |
Antibodies against a peptide of cholera toxin differing in cross-reactivity with the toxin differ in their specific interactions with the peptide as observed by 1H NMR spectroscopy.
Topics: Amino Acid Sequence; Antibodies; Antigens; Cholera Toxin; Cross Reactions; Epitopes; Lysine; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Protons; Tryptophan; Tyrosine | 1990 |
[Effect of ultraviolet light on the UV/VIS absorption spectrum of components of Eagle (MEM) cell culture medium].
Topics: Culture Media; In Vitro Techniques; Phenylalanine; Spectrophotometry, Ultraviolet; Spectrum Analysis; Staining and Labeling; Tryptophan; Tyrosine; Ultraviolet Rays | 1990 |
Effect of phenylalanine on pancreatic amylase secretion in chicks (Gallus domesticus).
Topics: Amylases; Animals; Chickens; Cholecystokinin; Fenclonine; Male; Pancreas; Phenylalanine; Tyrosine | 1990 |
Effects of glucose on the formation of PhIP in a model system.
Topics: Creatine; Ethylene Glycols; Glucose; Imidazoles; Models, Genetic; Mutagenicity Tests; Mutagens; Phenylalanine; Temperature; Tyrosine | 1991 |
Tryptophan and neutral amino acids in premenstrual syndrome.
Topics: Adult; Female; Follicular Phase; Humans; Isoleucine; Leucine; Luteal Phase; Phenylalanine; Premenstrual Syndrome; Tryptophan; Tyrosine; Valine | 1991 |
Pregnancy in phenylketonuria: dietary treatment aimed at normalising maternal plasma phenylalanine concentration.
Topics: Adult; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Preconception Care; Pregnancy; Tyrosine | 1991 |
Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats.
Topics: Animals; Aspartame; Brain; Drug Interactions; Male; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Tyrosine | 1991 |
Maternal PKU collaborative study: the effect of nutrient intake on pregnancy outcome.
Topics: Adult; Body Weight; Dietary Proteins; Energy Intake; Female; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Regression Analysis; Tyrosine | 1991 |
Rapid automated quantitation of isoleucine, leucine, tyrosine and phenylalanine from dried blood filter paper specimens.
Topics: Amino Acid Metabolism, Inborn Errors; Autoanalysis; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Neonatal Screening; Paper; Phenylalanine; Phenylketonurias; Tyrosine | 1991 |
Content of phenylalanine, tyrosine and their metabolites in CSF in phenylketonuria.
Topics: Child, Preschool; Chromatography, Ion Exchange; Gas Chromatography-Mass Spectrometry; Humans; Infant; Phenylalanine; Phenylketonurias; Tyrosine | 1991 |
Purification of prephenate dehydratase from Corynebacterium glutamicum by affinity chromatography.
Topics: Chromatography, Affinity; Corynebacterium; Phenylalanine; Prephenate Dehydrogenase; Tryptophan; Tyrosine | 1991 |
Rapid and sensitive high-performance liquid chromatographic method for the analysis of tryptophan, tyrosine and phenylalanine in biological samples.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Infant, Newborn; Phenylalanine; Reference Values; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1991 |
Effect of aromatic amino acids, pentylenetetrazole and yohimbine on isatin and tribulin activity in rat brain.
Topics: Animals; Brain; Diazepam; Isatin; Male; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Yohimbine | 1991 |
[Anticancer therapy with amino acid imbalance].
Topics: Amino Acids; Animals; Antineoplastic Agents; Arginine; Cysteine; Humans; Methionine; Neoplasms; Parenteral Nutrition, Total; Phenylalanine; Tyrosine; Valine | 1991 |
A comparative Raman spectroscopic study of cholinesterases.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Electrophorus; Humans; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Torpedo; Tryptophan; Tyrosine | 1991 |
Cyclic retro-inverso dipeptides with two aromatic side chains. I. Synthesis.
Topics: Amino Acid Sequence; Dipeptides; Indicators and Reagents; Peptides, Cyclic; Phenylalanine; Tyrosine | 1991 |
Cyclic retro-inverso dipeptides with two aromatic side chains. II. Conformational analysis.
Topics: Amino Acid Sequence; Dipeptides; Magnetic Resonance Spectroscopy; Models, Molecular; Peptides, Cyclic; Phenylalanine; Protein Conformation; Thermodynamics; Tyrosine | 1991 |
Thermolysin catalyzed semisynthesis of peptide hormones by introduction of Phe-NH2 or Tyr-NH2 at the carboxyl termini.
Topics: Amino Acid Sequence; Catalysis; Hormones; Molecular Sequence Data; Oligopeptides; Peptides; Phenylalanine; Thermolysin; Tyrosine | 1991 |
In vivo tyrosine hydroxylation in rat retina: effect of aspartame ingestion in rats pretreated with p-chlorophenylalanine.
Topics: Animals; Aspartame; Dihydroxyphenylalanine; Fenclonine; Hydroxylation; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Retina; Tyrosine | 1991 |
L-phenylalanine production by double auxotrophic mutants of Arthrobacter globiformis.
Topics: Arthrobacter; Biotin; Culture Media; Methylnitronitrosoguanidine; Mutagenesis; Phenylalanine; Tryptophan; Tyrosine | 1991 |
Heterozygous carriers of classical phenylketonuria in a sample of the Turkish population: detection by a spectrofluorimetric method.
Topics: Adolescent; Adult; Discriminant Analysis; Female; Gene Frequency; Genetic Carrier Screening; Humans; Male; Phenylalanine; Phenylketonurias; Spectrometry, Fluorescence; Turkey; Tyrosine | 1991 |
Metal-induced changes in the fluorescence properties of tyrosine and tryptophan site-specific mutants of oncomodulin.
Topics: Calcium; Calcium-Binding Proteins; Fluorescence; Magnesium; Metals; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Proteins; Phenylalanine; Protein Conformation; Spectrum Analysis; Tryptophan; Tyrosine | 1991 |
Mutational analysis of repression and activation of the tyrP gene in Escherichia coli.
Topics: Carrier Proteins; Deoxyribonuclease I; DNA Mutational Analysis; Escherichia coli; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Oligonucleotides; Operator Regions, Genetic; Phenylalanine; Promoter Regions, Genetic; Tyrosine | 1991 |
Importance of the position of TYR R boxes for repression and activation of the tyrP and aroF genes in Escherichia coli.
Topics: Base Sequence; Carrier Proteins; Deoxyribonuclease I; Escherichia coli; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mutagenesis; Operator Regions, Genetic; Phenylalanine; Promoter Regions, Genetic; Tyrosine | 1991 |
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut.
Topics: Animals; Aspartame; Aspartic Acid; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver Circulation; Methanol; Perfusion; Phenylalanine; Swine; Tyrosine | 1991 |
Simultaneous determination of urinary creatinine and aromatic amino acids by cation-exchange chromatography with ultraviolet detection.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Cations; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatinine; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 1991 |
Conformational stability of Cu,Zn-superoxide dismutase, the apoprotein, and its zinc-substituted derivatives: second-derivative spectroscopy of phenylalanine and tyrosine residues.
Topics: Animals; Apoproteins; Cattle; Kinetics; Phenylalanine; Protein Conformation; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tyrosine; Zinc | 1991 |
Transmembrane signalling by insulin via an insulin receptor mutated at tyrosines 1158, 1162, and 1163.
Topics: Aminoisobutyric Acids; Animals; Gene Expression; Insulin; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Signal Transduction; Thymidine; Transfection; Tumor Cells, Cultured; Tyrosine | 1991 |
Delayed plasma clearance of phenylalanine and tyrosine in elderly men.
Topics: Adult; Aged; Aging; Amino Acids; Dementia; Enteral Nutrition; Humans; Middle Aged; Phenylalanine; Tyrosine | 1991 |
Effect of precursor loading on the synthesis rate and release of dopamine and serotonin in the striatum: a microdialysis study in conscious rats.
Topics: Animals; Corpus Striatum; Dialysis; Dihydroxyphenylalanine; Dopamine; Eating; Haloperidol; Kinetics; Male; Phenylalanine; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine | 1991 |
A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity.
Topics: Base Sequence; Computer Simulation; DNA; DNA Polymerase I; DNA Replication; Escherichia coli; Kinetics; Molecular Sequence Data; Mutation; Phenylalanine; Serine; Tyrosine | 1991 |
Mutagenesis of the human transferrin receptor: two cytoplasmic phenylalanines are required for efficient internalization and a second-site mutation is capable of reverting an internalization-defective phenotype.
Topics: Amino Acid Sequence; Animals; Cell Line; Coated Pits, Cell-Membrane; Cricetinae; Cytoplasm; Endocytosis; Humans; Iron; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenotype; Phenylalanine; Receptors, Transferrin; Serine; Tyrosine | 1991 |
The tryptophan-specific permease gene, mtr, is differentially regulated by the tryptophan and tyrosine repressors in Escherichia coli K-12.
Topics: Amino Acid Transport Systems; Bacterial Proteins; beta-Galactosidase; Blotting, Northern; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Membrane Transport Proteins; Phenylalanine; Repressor Proteins; Transcription, Genetic; Transformation, Genetic; Tryptophan; Tyrosine | 1991 |
Motion of aromatic side chains, picosecond fluorescence, and internal energy transfer in Escherichia coli thioredoxin studied by site-directed mutagenesis, time-resolved fluorescence spectroscopy, and molecular dynamics simulations.
Topics: Amino Acids; Disulfides; Energy Transfer; Escherichia coli; Fluorescence Polarization; Hydrogen Bonding; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Thioredoxins; Tryptophan; Tyrosine; X-Ray Diffraction | 1991 |
Role of interactions involving C-terminal nonpolar residues of hirudin in the formation of the thrombin-hirudin complex.
Topics: Amino Acid Sequence; Binding Sites; Hirudins; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Conformation; Thermodynamics; Thrombin; Tyrosine | 1991 |
L-tyrosine-binding proteins on melanoma cells.
Topics: Animals; Antibodies; Blotting, Western; Carbon Radioisotopes; Chromatography, Affinity; Cricetinae; Levodopa; Melanoma; Molecular Weight; Monophenol Monooxygenase; Phenylalanine; Protein Binding; Tumor Cells, Cultured; Tyrosine | 1991 |
Effect of glucose and branched chain amino acid (BCAA) infusion on onset of liver regeneration and plasma amino acid pattern in partially hepatectomized rats.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Cell Division; DNA; Glucose; Hepatectomy; Infusions, Intravenous; Liver; Liver Regeneration; Phenylalanine; Rats; Rats, Inbred Strains; Thymidine; Tyrosine | 1991 |
Heterotropic interactions in aspartate transcarbamoylase: turning allosteric ATP activation into inhibition as a consequence of a single tyrosine to phenylalanine mutation.
Topics: Adenosine Triphosphate; Allosteric Regulation; Amino Acid Sequence; Aspartate Carbamoyltransferase; Enzyme Activation; Escherichia coli; Kinetics; Macromolecular Substances; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Recombinant Proteins; Tyrosine | 1991 |
Outcome in tyrosinaemia type II.
Topics: Amino Acid Metabolism, Inborn Errors; Child Development; Child, Preschool; Conjunctivitis; Humans; Infant; Infant, Newborn; Intelligence; Male; Phenylalanine; Tyrosine | 1991 |
Severity of illness correlates with alterations in energy metabolism in the pediatric intensive care unit.
Topics: Amino Acids, Branched-Chain; Biomarkers; Critical Care; Critical Illness; Energy Metabolism; Hospitals, University; Humans; Infant; Intensive Care Units, Pediatric; Length of Stay; Minnesota; Nitrogen; Nursing Care; Outcome Assessment, Health Care; Oxygen Consumption; Phenylalanine; Predictive Value of Tests; Prospective Studies; Risk Factors; Severity of Illness Index; Stress, Physiological; Tyrosine | 1991 |
Effect of branched-chain amino acid supplementation on mental performance.
Topics: Adult; Amino Acids, Branched-Chain; Exercise; Female; Humans; Mental Processes; Phenylalanine; Psychological Tests; Tryptophan; Tyrosine | 1991 |
Phenylalanine as substrate for tyrosine hydroxylase in bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Catecholamines; Cattle; Dihydroxyphenylalanine; Hydroxylation; Phenylalanine; Substrate Specificity; Tyrosine; Tyrosine 3-Monooxygenase | 1990 |
Gaucher disease associated with a unique KpnI restriction site: identification of the amino-acid substitution.
Topics: Base Sequence; Child; Deoxyribonucleases, Type II Site-Specific; DNA; Female; Gaucher Disease; Glucosidases; Glucosylceramidase; Humans; Molecular Sequence Data; Mutation; Phenylalanine; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Pseudogenes; Restriction Mapping; Tyrosine | 1990 |
Genetic analysis of treated and untreated phenylketonuria in one family.
Topics: Adolescent; Aged; DNA Mutational Analysis; Female; Haplotypes; Humans; Infant; Male; Mutation; Pedigree; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Polymorphism, Restriction Fragment Length; Tyrosine | 1990 |
Free amino acid analysis of guinea pig perilymph: a possible clinical assay for the PLF enigma?
Topics: Amino Acids; Animals; Arginine; Asparagine; Biomarkers; Chromatography; Chromatography, High Pressure Liquid; Fistula; Glutamates; Glutamic Acid; Glutamine; Guinea Pigs; Histidine; Isoleucine; Labyrinth Diseases; Leucine; Lysine; Perilymph; Phenylalanine; Spectrometry, Fluorescence; Threonine; Tyrosine; Valine | 1990 |
The tyrosine-225 to phenylalanine mutation of Escherichia coli aspartate aminotransferase results in an alkaline transition in the spectrophotometric and kinetic pKa values and reduced values of both kcat and Km.
Topics: Aspartate Aminotransferases; Base Sequence; Circular Dichroism; Cloning, Molecular; Escherichia coli; Hydrogen Bonding; Kinetics; Mathematics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligonucleotide Probes; Phenylalanine; Protein Conformation; Pyridoxal Phosphate; Pyridoxamine; Spectrophotometry; Tyrosine | 1991 |
Structure-function studies of human aromatase by site-directed mutagenesis: kinetic properties of mutants Pro-308----Phe, Tyr-361----Phe, Tyr-361----Leu, and Phe-406----Arg.
Topics: Amino Acid Sequence; Aminoglutethimide; Androstenedione; Animals; Arginine; Aromatase; Base Sequence; Cell Line; Humans; Kinetics; Leucine; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oligonucleotide Probes; Phenylalanine; Proline; Substrate Specificity; Testosterone; Transfection; Tyrosine | 1991 |
Phenylethylaminergic mechanisms in attention-deficit disorder.
Topics: Attention Deficit Disorder with Hyperactivity; Child; Humans; Phenethylamines; Phenylacetates; Phenylalanine; Reference Values; Tyrosine | 1991 |
Interspecies and interstrain studies on the increased susceptibility to metrazol-induced convulsions in animals given aspartame.
Topics: Animals; Aspartame; Brain; Drug Synergism; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Species Specificity; Tyrosine | 1991 |
Aromatic-aromatic interactions and protein stability. Investigation by double-mutant cycles.
Topics: Amino Acid Sequence; Bacillus; Bacterial Proteins; Base Sequence; DNA; Enzyme Stability; Hydrocarbons; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mathematics; Molecular Sequence Data; Mutation; Phenols; Phenylalanine; Protein Denaturation; Ribonucleases; Thermodynamics; Tyrosine; Urea | 1991 |
High directional Monte Carlo procedure coupled with the temperature heating and annealing as a method to obtain the global energy minimum structure of polypeptides and proteins.
Topics: Enkephalin, Methionine; Glycine; Mathematics; Methionine; Monte Carlo Method; Phenylalanine; Protein Conformation; Surface Properties; Temperature; Torsion Abnormality; Tyrosine | 1991 |
Regulation of chorismate mutase activity of various yeast species by aromatic amino acids.
Topics: Amino Acids; Chorismate Mutase; Enzyme Activation; Isoenzymes; Phenylalanine; Tryptophan; Tyrosine; Yeasts | 1991 |
The use of tryptophan mutants in identifying the 296 nm transient absorbing species during the photocycle of bacteriorhodopsin.
Topics: Bacteriorhodopsins; Cysteine; Kinetics; Phenylalanine; Spectrum Analysis; Tryptophan; Tyrosine | 1991 |
7-Tetrahydrobiopterin is an uncoupled cofactor for rat hepatic phenylalanine hydroxylase.
Topics: Animals; Biopterins; Hydrogen Peroxide; Hydroxylation; Kinetics; Liver; NAD; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Tyrosine | 1991 |
Transport of L-tyrosine by B16/F10 melanoma cells: the effect of the intracellular content of other amino acids.
Topics: Amino Acids; Animals; Biological Transport; Melanoma, Experimental; Phenylalanine; Tumor Cells, Cultured; Tyrosine | 1990 |
Effects of dietary tyrosine on L-dopa- and amphetamine-induced changes in locomotor activity and neurochemistry in mice.
Topics: Animals; Biogenic Monoamines; Body Weight; Brain Chemistry; Dextroamphetamine; Diet; Drug Interactions; Levodopa; Male; Mice; Motor Activity; Phenylalanine; Tyrosine | 1990 |
Remnants of an ancient pathway to L-phenylalanine and L-tyrosine in enteric bacteria: evolutionary implications and biotechnological impact.
Topics: Amino Acids, Dicarboxylic; Biological Evolution; Chromatography, High Pressure Liquid; Cyclohexanecarboxylic Acids; Cyclohexenes; Escherichia coli; Klebsiella pneumoniae; Phenylalanine; Salmonella typhimurium; Transaminases; Tyrosine | 1990 |
Synthesis, characterization, and DNA binding studies of some mixed-ligand platinum(II) complexes of 1,10-phenanthroline and amino acids.
Topics: Alanine; Amino Acids; Animals; Antineoplastic Agents; Cattle; Cisplatin; DNA; Ethidium; Glycine; Intercalating Agents; Leucine; Magnetic Resonance Spectroscopy; Phenanthrolines; Phenylalanine; Platinum; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1990 |
Structural studies of metalloporphyrins. Part XIa: Complexes of water-soluble zinc(II) porphyrins with amino acids: influence of ligand-ligand interactions on the stability of the complexes.
Topics: Amino Acids; Anions; Cations; Chemical Phenomena; Chemistry, Physical; Drug Stability; Electrochemistry; Magnetic Resonance Spectroscopy; Metalloporphyrins; Molecular Structure; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine; Zinc | 1990 |
Sensitivity of efflux-driven carrier turnover to external pH in mutants of the Escherichia coli lactose carrier that have tyrosine or phenylalanine substituted for histidine-322. A comparison of lactose and melibiose.
Topics: Disaccharides; Edetic Acid; Escherichia coli; Escherichia coli Proteins; Histidine; Hydrogen-Ion Concentration; Kinetics; Lactose; Melibiose; Membrane Transport Proteins; Models, Theoretical; Monosaccharide Transport Proteins; Mutation; Phenylalanine; Symporters; Tyrosine | 1990 |
Metabolism of intravenous phenylalanine by babies born before 33 weeks of gestation.
Topics: Chemical Phenomena; Chemistry; Humans; Hydroxybenzoates; Infant, Newborn; Infant, Premature; Parenteral Nutrition; Phenylalanine; Tyrosine | 1990 |
Activities of native and tyrosine-69 mutant phospholipases A2 on phospholipid analogues. A reevaluation of the minimal substrate requirements.
Topics: Animals; Base Sequence; Esters; Lysine; Molecular Sequence Data; Mutation; Pancreas; Phenylalanine; Phosphates; Phosphatidylcholines; Phospholipases; Phospholipases A; Phospholipases A2; Phospholipids; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Swine; Tyrosine | 1990 |
Identification and quantitation of phenylalanine, tyrosine and dihydroxyphenylalanine in the thoracic nervous system of the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry.
Topics: Animals; Deuterium; Dihydroxyphenylalanine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Grasshoppers; Male; Nervous System; Phenylalanine; Propanols; Thorax; Tyrosine | 1990 |
Phenylethylamine metabolism in Tourette's syndrome.
Topics: Child; Female; Humans; Male; Phenethylamines; Phenylacetates; Phenylalanine; Reference Values; Tourette Syndrome; Tyrosine | 1990 |
Tyrosine- and phenylalanine-restricted formula diet augments immunocompetence in healthy humans.
Topics: Body Composition; Diet; Dietary Proteins; Female; Humans; Immunocompetence; Killer Cells, Natural; Male; Phenylalanine; Platelet Aggregation; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Tyrosine | 1990 |
Eliminating phenylalanine and tyrosine from diet slows cancer spread.
Topics: Animals; Melanoma, Experimental; Mice; Phenylalanine; Tyrosine | 1990 |
Methods for the enzymatic synthesis of tyrosine and phenylalanine labeled with nitrogen-13.
Topics: Enzymes, Immobilized; Isotope Labeling; Nitrogen Radioisotopes; Phenylalanine; Tyrosine | 1990 |
The insulin receptor with phenylalanine replacing tyrosine-1146 provides evidence for separate signals regulating cellular metabolism and growth.
Topics: Animals; Base Sequence; Cell Division; Cell Line; DNA Replication; Glycogen Synthase; Insulin; Kinetics; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Phenylalanine; Phosphorylation; Plasmids; Protein-Tyrosine Kinases; Receptor, Insulin; Signal Transduction; Transfection; Tyrosine | 1990 |
Initial characterization of site-directed mutants of tyrosine M210 in the reaction centre of Rhodobacter sphaeroides.
Topics: Bacterial Proteins; Base Sequence; Cytochrome c Group; Leucine; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oxidation-Reduction; Phenylalanine; Photosynthesis; Photosynthetic Reaction Center Complex Proteins; Restriction Mapping; Rhodobacter sphaeroides; Spectrophotometry; Tyrosine | 1990 |
Formation of ortho-tyrosine by radiation and organic solvents in chicken tissue.
Topics: Animals; Cattle; Chickens; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Free Radicals; Hydroxides; Hydroxyl Radical; Mass Spectrometry; Muscles; Phenylalanine; Solvents; Tyrosine | 1990 |
Cation-dependent mannose 6-phosphate receptor contains two internalization signals in its cytoplasmic domain.
Topics: Amino Acid Sequence; Animals; Cations; Cell Membrane; Chromosome Deletion; Cytoplasm; Endocytosis; Kinetics; L Cells; Mannosephosphates; Mice; Molecular Sequence Data; Phenylalanine; Plasmids; Receptor, IGF Type 2; Receptors, Cell Surface; Transfection; Tyrosine | 1990 |
Regulation of chorismate mutase in Saccharomyces cerevisiae.
Topics: Chorismate Mutase; Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Fungal; Genes, Regulator; Isomerases; Mutation; Phenylalanine; Plasmids; Saccharomyces cerevisiae; Transcription, Genetic; Transformation, Genetic; Tryptophan; Tyrosine | 1990 |
Effects of elevated temperature on protein breakdown in muscles from septic rats.
Topics: Animals; Carbon Radioisotopes; Fever; Male; Methylhistidines; Muscles; Phenylalanine; Protein Biosynthesis; Proteins; Radioisotope Dilution Technique; Rats; Rats, Inbred Strains; Reference Values; Sepsis; Tyrosine | 1990 |
Assignment of tyrosine resonances in the 1H-NMR spectrum of tryptophan synthase alpha-subunit. Monitoring conformational changes due to substitutions at position 49.
Topics: Binding Sites; Escherichia coli; Glutamine; Glycine; Magnetic Resonance Spectroscopy; Mutation; Phenylalanine; Protein Conformation; Tryptophan Synthase; Tyrosine | 1990 |
In vivo enzyme activity in inborn errors of metabolism.
Topics: Adult; Bicarbonates; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Hydroxylation; Isotope Labeling; Leucine; Male; Malonates; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methylmalonic Acid; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Propionates; Radioisotope Dilution Technique; Reference Values; Tyrosine | 1990 |
Substitution of Tyr254 with Phe at the active site of flavocytochrome b2: consequences on catalysis of lactate dehydrogenation.
Topics: Binding Sites; Catalysis; Deuterium; Fungal Proteins; Hydroxybutyrates; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactates; Lactic Acid; Models, Molecular; Phenylalanine; Protein Conformation; Pyruvates; Saccharomyces cerevisiae; Tyrosine | 1990 |
Ultraviolet-visible transient spectroscopy of bacteriorhodopsin mutants. Evidence for two forms of tyrosine-185----phenylalanine.
Topics: Amino Acid Sequence; Bacteriorhodopsins; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutation; Phenylalanine; Protein Conformation; Spectrophotometry; Tyrosine | 1990 |
Evidence for a close link between the thyroid hormone transport system and the aromatic amino acid transport system T in erythrocytes.
Topics: Animals; Biological Transport; Erythrocytes; Ethylmaleimide; Humans; In Vitro Techniques; Kinetics; Male; Phenylalanine; Rats; Rats, Inbred Strains; Sheep; Thyroxine; Triiodothyronine; Tryptophan; Tyrosine | 1990 |
Effect of the tyrosine 96 hydrogen bond on the inactivation of cytochrome P-450cam induced by hydrostatic pressure.
Topics: Camphor; Cytochrome P-450 Enzyme System; Cytochromes; Hydrogen Bonding; Hydrostatic Pressure; Mutagenesis, Site-Directed; Phenylalanine; Pseudomonas; Spectrum Analysis; Tyrosine | 1990 |
L-tyrosine potentiates the anorexia induced by mixed-acting sympathomimetic drugs in hyperphagic rats.
Topics: alpha-Methyltyrosine; Amino Acids; Animals; Anorexia; Dose-Response Relationship, Drug; Drug Synergism; Eating; Hyperphagia; Male; Methyltyrosines; Phenylalanine; Rats; Rats, Inbred Strains; Sympathomimetics; Tyrosine; Valine | 1990 |
Plasma amino acids in attention deficit disorder.
Topics: Amino Acids; Attention Deficit Disorder with Hyperactivity; Child; Female; Histidine; Humans; Isoleucine; Male; Phenylalanine; Tryptophan; Tyrosine | 1990 |
Phenylalanine flux, oxidation, and conversion to tyrosine in humans studied with L-[1-13C]phenylalanine.
Topics: Adult; Carbon Isotopes; Diet; Energy Metabolism; Humans; Isotope Labeling; Male; Mathematics; Models, Biological; Oxidation-Reduction; Phenylalanine; Tyrosine | 1990 |
A multivariate analysis of red blood cell membrane transports and plasma levels of L-tyrosine and L-tryptophan in depressed patients before treatment and after clinical improvement.
Topics: Adult; Bipolar Disorder; Depressive Disorder; Erythrocyte Membrane; Female; Follow-Up Studies; Hospitalization; Humans; Male; Multivariate Analysis; Phenylalanine; Psychiatric Status Rating Scales; Tryptophan; Tyrosine | 1990 |
Evolution of aromatic amino acid biosynthesis and application to the fine-tuned phylogenetic positioning of enteric bacteria.
Topics: Anthranilate Phosphoribosyltransferase; Anthranilate Synthase; Biological Evolution; Chorismate Mutase; Enterobacteriaceae; Genes, Bacterial; Multigene Family; Phenylalanine; Phylogeny; Prephenate Dehydratase; Protein Sorting Signals; RNA, Ribosomal, 16S; RNA, Ribosomal, 5S; Tryptophan; Tyrosine | 1990 |
Septic encephalopathy. Evidence for altered phenylalanine metabolism and comparison with hepatic encephalopathy.
Topics: Ammonia; Bacterial Infections; Brain Diseases, Metabolic; Glutamine; Hepatic Encephalopathy; Humans; Phenylacetates; Phenylalanine; Tryptophan; Tyrosine | 1990 |
Evidence for an intracerebral action of phenylalanine in stimulation of prolactin secretion: interaction of large neutral amino acids.
Topics: Adult; Biological Transport; Blood-Brain Barrier; Cerebral Cortex; Humans; Hypothalamus; Infusions, Intravenous; Male; Phenylalanine; Pituitary Gland; Prolactin; Tyrosine; Valine | 1990 |
Determination of tryptophan, tyrosine, and phenylalanine by second derivative spectrophotometry.
Topics: Humans; Indicators and Reagents; Phenylalanine; Serum Albumin; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1990 |
Reaction of alpha-tubulin with iodotyrosines catalyzed by tubulin:tyrosine ligase: carboxy-terminal labeling of tubulin with [125I]monoiodotyrosine.
Topics: Iodine Radioisotopes; Isotope Labeling; Monoiodotyrosine; Peptide Synthases; Phenylalanine; Protein Engineering; Structure-Activity Relationship; Substrate Specificity; Thyronines; Tubulin; Tyrosine | 1990 |
Relationship between L-tryptophan uptake and L-tryptophan 2,3-dioxygenase activity in rat hepatocytes.
Topics: Animals; Biological Transport; Hydrocortisone; Kinetics; Leucine; Liver; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase; Tyrosine | 1990 |
Brain phenylalanine and tyrosine levels and hepatic encephalopathy induced by CCl4 in rats.
Topics: 2,4-Dinitrophenol; Amino Acids; Ammonium Chloride; Animals; Brain; Brain Chemistry; Carbon Tetrachloride; Dinitrophenols; Hepatic Encephalopathy; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1990 |
Side chain mobility in bovine calbindin D9k. Rotational motion of Tyr13.
Topics: Animals; Calbindins; Cattle; Mathematics; Mutation; Phenylalanine; Protein Conformation; S100 Calcium Binding Protein G; Spectrometry, Fluorescence; Tyrosine | 1990 |
Chemistry in a microenvironment of low pH, generated with the aid of an immobilized proteinase.
Topics: Alanine; Buffers; Chemical Phenomena; Chemistry; Chymotrypsin; Collodion; Diffusion; Enzymes, Immobilized; Hydrazines; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Phenylalanine; Prodrugs; Solutions; Tyrosine | 1990 |
Characterization of lysosomal monoiodotyrosine transport in rat thyroid cells. Evidence for transport by system h.
Topics: Animals; Binding, Competitive; Biological Transport; Carrier Proteins; Cell Line; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysosomes; Monoiodotyrosine; Phenylalanine; Rats; Structure-Activity Relationship; Thyroid Gland; Thyrotropin; Tyrosine | 1990 |
Significant phenylalanine hydroxylation in vivo in patients with classical phenylketonuria.
Topics: Adult; Female; Humans; Hydroxylation; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1990 |
Dietary treatment eliminates succinylacetone from the urine of a patient with tyrosinaemia type 1.
Topics: Amino Acid Metabolism, Inborn Errors; Female; Heme; Heptanoates; Heptanoic Acids; Humans; Infant; Methionine; Phenylalanine; Tyrosine | 1990 |
Plasma and brain kinetics of large neutral amino acids and of striatum monoamines in rats given aspartame.
Topics: Animals; Aspartame; Biogenic Monoamines; Corpus Striatum; Dipeptides; Phenylalanine; Rats; Rats, Inbred Strains; Time Factors; Tyrosine | 1990 |
3-azido-L-tyrosine as a photoinhibitor of tubulin:tyrosine ligase. Role of thiol groups.
Topics: Affinity Labels; Animals; Azides; Brain; Chloromercuribenzoates; In Vitro Techniques; p-Chloromercuribenzoic Acid; Peptide Synthases; Phenylalanine; Photochemistry; Structure-Activity Relationship; Sulfhydryl Compounds; Swine; Tubulin; Tyrosine | 1990 |
Asymmetrical transport of amino acids across the blood-brain barrier in humans.
Topics: Adult; Amino Acids; Arginine; Biological Transport, Active; Blood-Brain Barrier; Cell Membrane Permeability; Female; Humans; Leucine; Male; Middle Aged; Models, Neurological; Phenylalanine; Tryptophan; Tyrosine | 1990 |
Effects of aging and xerosis on the amino acid composition of human skin.
Topics: Aging; Amino Acids; Female; Filaggrin Proteins; Glycine; Humans; Ichthyosis; Leucine; Phenylalanine; Skin; Tyrosine | 1990 |
Tyrosine formation from phenylalanine by ultraviolet irradiation.
Topics: Hydroxylation; Phenylalanine; Tyrosine; Ultraviolet Rays | 1990 |
Estimation of the isoleucine and aromatic amino acid requirements of pregnant swine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Female; Isoleucine; Phenylalanine; Pregnancy; Pregnancy, Animal; Random Allocation; Swine; Tyrosine | 1990 |
Effect of insulin on protein synthesis and degradation in skeletal muscle after exercise.
Topics: Animals; Carbon Radioisotopes; Insulin; Male; Muscles; Perfusion; Phenylalanine; Physical Exertion; Protein Biosynthesis; Rats; Rats, Inbred Strains; Reference Values; Tyrosine | 1990 |
Proton NMR studies of transforming and nontransforming H-ras p21 mutants.
Topics: Base Sequence; Cell Transformation, Neoplastic; DNA; Guanosine Diphosphate; Guanosine Triphosphate; Magnesium; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Mutation; Oncogene Protein p21(ras); Phenylalanine; Protein Conformation; Tyrosine | 1990 |
Metallothionein protein variants generated in rat liver as a result of DNA and RNA ethylations by the carcinogen diethylnitrosamine.
Topics: Alkylation; Animals; Cysteine; Diethylnitrosamine; DNA; Genetic Variation; Liver; Male; Metallothionein; Phenylalanine; Rats; Rats, Inbred Strains; RNA; Tyrosine | 1986 |
Synthesis and high affinity uptake of serotonin and dopamine by human Y79 retinoblastoma cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biological Transport; Cell Line; Dihydroxyphenylalanine; Dopamine; Eye Neoplasms; Humans; Hydroxyindoleacetic Acid; Kinetics; Norepinephrine; Phenylalanine; Retinoblastoma; Serotonin; Tryptophan; Tyrosine | 1987 |
Acute effect of protein or carbohydrate breakfasts on human cerebrospinal fluid monoamine precursor and metabolite levels.
Topics: Dietary Carbohydrates; Dietary Proteins; Histidine; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
Increased neurotransmitter biosynthesis in phenylketonuria induced by phenylalanine restriction or by supplementation of unrestricted diet with large amounts of tyrosine.
Topics: Adolescent; Adult; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Reaction Time; Tyrosine; Visual Perception | 1988 |
Aspartame and the rat brain monoaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartame; Biogenic Monoamines; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Hippocampus; Hydroxyindoleacetic Acid; Nucleus Accumbens; Phenylalanine; Plasma; Rats; Serotonin; Tyrosine | 1988 |
Effect of sustained exercise on plasma amino acid concentrations and on 5-hydroxytryptamine metabolism in six different brain regions in the rat.
Topics: Amino Acids, Branched-Chain; Animals; Brain; Dopamine; Fatty Acids, Nonesterified; Female; Hydroxyindoleacetic Acid; Norepinephrine; Phenylalanine; Physical Endurance; Physical Exertion; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine | 1989 |
Theoretical study of the contribution of aromatic side chains to the circular dichroism of basic bovine pancreatic trypsin inhibitor.
Topics: Animals; Aprotinin; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; Phenylalanine; Protein Conformation; Tyrosine | 1989 |
Regulation of pteridine biosynthesis and aromatic amino acid hydroxylation in Drosophila melanogaster.
Topics: Amino Acids; Animals; Drosophila melanogaster; Hydroxylation; Mutation; Phenylalanine; Pteridines; Tryptophan; Tyrosine | 1989 |
1H NMR studies of aliphatic ligand binding to human plasminogen kringle 4.
Topics: Histidine; Humans; Hydrogen; Kinetics; Ligands; Lysine; Magnetic Resonance Spectroscopy; Phenylalanine; Plasminogen; Protein Binding; Protein Conformation; Tryptophan; Tyrosine | 1989 |
Nonphosphorylatable substrate analogs selectively block autophosphorylation and activation of the insulin receptor, epidermal growth factor receptor, and pp60v-src kinases.
Topics: Adenosine Triphosphate; Binding, Competitive; Enzyme Activation; ErbB Receptors; Kinetics; Methyltyrosines; Oncogene Protein pp60(v-src); Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Retroviridae Proteins; Structure-Activity Relationship; Tumor Cells, Cultured; Tyrosine | 1989 |
Plasma amino acid concentrations in parenterally fed preterm infants.
Topics: Amino Acids; Humans; Infant Nutritional Physiological Phenomena; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Parenteral Nutrition; Phenylalanine; Reference Values; Tyrosine | 1989 |
Binding kinetics of mutated insulin receptors in transfected cells grown in suspension culture: application to the Tyr----Phe 960 insulin receptor mutant.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; Glycogen Synthase; Kinetics; Mutation; Phenylalanine; Protein-Tyrosine Kinases; Receptor, Insulin; Transfection; Tyrosine | 1989 |
Phenylalanine-to-tyrosine singlet energy transfer in the archaebacterial histone-like protein HTa.
Topics: Archaea; Bacterial Proteins; Carboxypeptidases; DNA-Binding Proteins; Energy Transfer; Phenylalanine; Spectrometry, Fluorescence; Tyrosine | 1989 |
[Studies of the effect of a protein-free diet and branched-chain amino acids (preparation Aminosteril-Hepa) on selected biochemical indicators in chronic experimental hepatic encephalopathy].
Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Chronic Disease; Dietary Proteins; Hepatic Encephalopathy; Male; Parenteral Nutrition; Phenols; Phenylalanine; Rats; Rats, Inbred Strains; Thioacetamide; Tryptophan; Tyrosine | 1989 |
In vivo metabolism of atrial natriuretic peptide: identification of plasma metabolites and enzymes responsible for their generation.
Topics: Animals; Atrial Natriuretic Factor; Carboxypeptidases; Endopeptidases; Kidney; Phenylalanine; Rats; Thiorphan; Tyrosine | 1989 |
Ligand-binding effects on the kringle 4 domain from human plasminogen: a study by laser photo-CIDNP 1H-NMR spectroscopy.
Topics: Aminocaproic Acid; Antifibrinolytic Agents; Benzylamines; Histidine; Humans; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Phenylalanine; Photochemistry; Plasminogen; Protons; Tryptophan; Tyrosine | 1989 |
Galactoside-dependent proton transport by mutants of the Escherichia coli lactose carrier. Replacement of histidine 322 by tyrosine or phenylalanine.
Topics: Biological Transport; Escherichia coli; Escherichia coli Proteins; Galactosides; Glycosides; Histidine; Melibiose; Membrane Potentials; Membrane Transport Proteins; Monosaccharide Transport Proteins; Mutation; Phenylalanine; Protons; Structure-Activity Relationship; Symporters; Tyrosine | 1989 |
Structural significance of an internal water molecule studied by site-directed mutagenesis of tyrosine-67 in rat cytochrome c.
Topics: Animals; Cytochrome c Group; DNA Mutational Analysis; Heme; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Phenylalanine; Protein Conformation; Rats; Recombinant Proteins; Structure-Activity Relationship; Thermodynamics; Tyrosine; Urea; Water | 1989 |
Aromatic aminotransferase activity and indoleacetic acid production in Rhizobium meliloti.
Topics: Cloning, Molecular; DNA Mutational Analysis; DNA Transposable Elements; Genomic Library; Indoleacetic Acids; Molecular Weight; Mutation; Phenylalanine; Restriction Mapping; Rhizobium; Transaminases; Tryptophan Transaminase; Tyrosine | 1989 |
Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I.
Topics: Base Sequence; Binding Sites; Cloning, Molecular; Codon; DNA Topoisomerases, Type I; Escherichia coli; Gene Expression; Genes, Viral; Molecular Sequence Data; Mutation; Phenylalanine; Recombinant Proteins; Saccharomyces; Tyrosine; Vaccinia virus; Viral Structural Proteins | 1989 |
Comparison of cooperative and isolated site binding of T4 gene 32 protein to ssDNA by 1H NMR.
Topics: Binding Sites; DNA-Binding Proteins; DNA, Single-Stranded; Kinetics; Magnetic Resonance Spectroscopy; Phenylalanine; Protons; Tyrosine; Viral Proteins | 1989 |
The utilization of nitrogen for growth in mice fed blends of purified proteins.
Topics: Amino Acids; Animals; Blood Urea Nitrogen; Caseins; Dietary Proteins; Gelatin; Gliadin; Glutamates; Glutamic Acid; Glycine; Lactalbumin; Male; Mice; Nitrogen; Phenylalanine; Tyrosine; Weaning; Weight Gain; Zein | 1989 |
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults.
Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine | 1989 |
The biochemical basis for growth inhibition by L-phenylalanine in Neisseria gonorrhoeae.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Allosteric Regulation; Growth Inhibitors; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Phenotype; Phenylalanine; Phenylpyruvic Acids; Transaminases; Tyrosine | 1989 |
Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A.
Topics: Binding Sites; Carboxypeptidases; Carboxypeptidases A; Glutamates; Glutamic Acid; Hydrogen Bonding; Phenylalanine; Protein Conformation; Tyrosine; Water; X-Ray Diffraction; Zinc | 1989 |
In vivo tyrosine hydroxylation rate in retina: effects of phenylalanine and tyrosine administration in rats pretreated with p-chlorophenylalanine.
Topics: Animals; Dose-Response Relationship, Drug; Fenclonine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Retina; Tyrosine; Tyrosine 3-Monooxygenase | 1989 |
Clinical chemical responses to experimental airborne legionellosis in the guinea-pig.
Topics: Acute-Phase Proteins; Animals; Blood Proteins; Body Temperature; Copper; Female; Guinea Pigs; Iron; Legionnaires' Disease; Lung; Muramidase; Phenylalanine; Sepsis; Tyrosine; Zinc | 1985 |
Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model.
Topics: Animals; Arginine; Asparagine; Aspartic Acid; Cattle; Chemical Phenomena; Chemistry, Physical; Glutamates; Glutamine; Histidine; Mathematics; Models, Molecular; Phenylalanine; Ribonuclease, Pancreatic; Sulfates; Tyrosine; X-Ray Diffraction | 1989 |
Diurnal rhythm in absolute and relative concentrations of large neutral amino acids in human plasma.
Topics: Adult; Amino Acids; Circadian Rhythm; Humans; Isoleucine; Leucine; Male; Middle Aged; Phenylalanine; Reference Values; Tryptophan; Tyrosine; Valine | 1989 |
1H NMR studies on protein binding of histidine, tyrosine and phenylalanine in blood plasma.
Topics: Animals; Blood Proteins; Cattle; Histidine; Humans; In Vitro Techniques; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Binding; Tyrosine | 1989 |
High resolution 1H-NMR studies of Des-(B26-B30)-insulin; assignment of resonances and properties of aromatic residues.
Topics: Amino Acid Sequence; Animals; Hydrogen-Ion Concentration; Insulin; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Swine; Tyrosine | 1989 |
Neutral amino acid plasma levels in healthy subjects: effect of complex carbohydrate consumed along with protein.
Topics: Adult; Amino Acids; Blood Glucose; Dietary Carbohydrates; Dietary Proteins; Female; Humans; Insulin; Isoleucine; Kinetics; Leucine; Phenylalanine; Reference Values; Tryptophan; Tyrosine; Valine | 1989 |
Structural consequences of a one atom mutation on aspartate transcarbamylase from E. coli.
Topics: Allosteric Regulation; Aspartate Carbamoyltransferase; Computer Simulation; Escherichia coli; Molecular Structure; Phenylalanine; Scattering, Radiation; Solutions; Structure-Activity Relationship; Tyrosine; X-Rays | 1989 |
Staphylococcal nuclease active-site amino acids: pH dependence of tyrosines and arginines by 13C NMR and correlation with kinetic studies.
Topics: Arginine; Binding Sites; Catalysis; Cloning, Molecular; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Micrococcal Nuclease; Models, Molecular; Mutation; Phenylalanine; Temperature; Thermodynamics; Transformation, Bacterial; Tyrosine | 1989 |
NMR study of human mutant hemoglobins synthesized in Escherichia coli. Consequences of tyrosine alpha 42 substitutions.
Topics: Escherichia coli; Genetic Vectors; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mutation; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1989 |
Site-specific mutation of Tyr240----Phe in the catalytic chain of Escherichia coli aspartate transcarbamylase. Consequences for kinetic mechanism.
Topics: Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Catalysis; Computer Simulation; Escherichia coli; Kinetics; Mutation; Phenylalanine; Phosphates; Protein Conformation; Structure-Activity Relationship; Thermodynamics; Tyrosine | 1989 |
Regulatory behavior of Escherichia coli aspartate transcarbamylase altered by site-specific mutation of Tyr240----Phe in the catalytic chain.
Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Aspartic Acid; Carbamyl Phosphate; Catalysis; Computer Simulation; Cytidine Triphosphate; Enzyme Activation; Escherichia coli; Kinetics; Mutation; Phenylalanine; Phosphates; Structure-Activity Relationship; Thermodynamics; Tyrosine | 1989 |
Effects of running the Boston marathon on plasma concentrations of large neutral amino acids.
Topics: Amino Acids; Humans; Isoleucine; Leucine; Methionine; Phenylalanine; Physical Exertion; Reference Values; Running; Tryptophan; Tyrosine; Valine | 1989 |
Rapid measurement of whole body and forearm protein turnover using a [2H5]phenylalanine model.
Topics: Adult; Female; Forearm; Humans; Leucine; Male; Models, Biological; Muscles; Phenylalanine; Proteins; Tyrosine | 1989 |
Proton nuclear magnetic resonance characterization of the aromatic residues in the variant-3 neurotoxin from Centruroides sculpturatus Ewing.
Topics: Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Neurotoxins; Phenylalanine; Protein Conformation; Scorpion Venoms; Tryptophan; Tyrosine | 1989 |
Structure of a single amino acid mutant of aspartate carbamoyltransferase at 2.5-A resolution: implications for the cooperative mechanism.
Topics: Aspartate Carbamoyltransferase; Binding Sites; Macromolecular Substances; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Tyrosine; X-Ray Diffraction | 1989 |
Proton nuclear magnetic resonance study on the aromatic amino acid-guanine nucleotide system: effect of base methylation on the stacking interaction with tyrosine and phenylalanine.
Topics: Amino Acids; Guanine Nucleotides; Magnetic Resonance Spectroscopy; Methylation; Phenylalanine; Tyrosine | 1989 |
Evidence for the formation of the 4a-carbinolamine during the tyrosine-dependent oxidation of tetrahydrobiopterin by rat liver phenylalanine hydroxylase.
Topics: Animals; Biopterins; Hydrogen-Ion Concentration; Kinetics; Liver; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Rats; Spectrophotometry, Ultraviolet; Tyrosine | 1989 |
Prolactin stimulation by protein is mediated by amino acids in humans.
Topics: Adult; Dietary Proteins; Dose-Response Relationship, Drug; Female; Humans; Male; Naloxone; Phenylalanine; Prolactin; Sex Factors; Time Factors; Tyrosine; Vagotomy | 1989 |
Hypopigmentation: a common feature of Prader-Labhart-Willi syndrome.
Topics: Adolescent; Adult; Catecholamines; Child; Child, Preschool; Chromosome Deletion; Chromosomes, Human, Pair 15; Eye Color; Female; Hair Color; Humans; Infant; Male; Melanocyte-Stimulating Hormones; Phenylalanine; Pigmentation Disorders; Prader-Willi Syndrome; Skin; Tyrosine | 1989 |
High-performance liquid chromatographic determination of m-tyrosine and o-tyrosine in rat urine.
Topics: Animals; Chromatography, High Pressure Liquid; Male; Phenylalanine; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Tyrosine | 1989 |
Minimum-structure enkephalin analogues incorporating L-tyrosine, D(or L)-phenylalanine, and a diamine spacer.
Topics: Animals; Chemical Phenomena; Chemistry; Diamines; Enkephalins; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Male; Molecular Conformation; Muscle Contraction; Muscle, Smooth; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1989 |
Excretion of amino acids by 1,2,4-triazole-3-alanine-resistant mutants of Methanococcus voltae.
Topics: Alanine; Amino Acids; Drug Resistance, Microbial; Euryarchaeota; Histidine; Methionine; Mutation; Phenylalanine; Proline; Tyrosine | 1989 |
Mechanisms of phenylalanine-induced pressor effects in conscious rats.
Topics: Animals; Biological Availability; Blood Pressure; Carbidopa; Desipramine; Dose-Response Relationship, Drug; Heart Rate; Male; Phenethylamines; Phenylalanine; Prazosin; Rats; Rats, Inbred Strains; Tyrosine; Valine | 1989 |
Terminal phenylalanine and tyrosine biosynthesis of Microtetraspora glauca.
Topics: Chorismate Mutase; Hydro-Lyases; Hydroxymercuribenzoates; Kinetics; Oxidoreductases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Streptomycetaceae; Tyrosine | 1989 |
Daily profiles of plasma phenylalanine and tyrosine in patients with osteogenic sarcoma during treatment with high-dose methotrexate-citrovorum rescue.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Female; Humans; Leg; Leucovorin; Male; Methotrexate; Osteosarcoma; Phenylalanine; Time Factors; Tyrosine | 1989 |
Determination of the contributions of individual aromatic residues to the CD spectrum of IL-1 beta using site directed mutagenesis.
Topics: Circular Dichroism; Humans; Interleukin-1; Mutation; Phenylalanine; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1989 |
Complete assignment of the aromatic proton magnetic resonance spectrum of the kringle 1 domain from human plasminogen: structure of the ligand-binding site.
Topics: Amino Acid Sequence; Binding Sites; Histidine; Humans; Ligands; Magnetic Resonance Spectroscopy; Metalloendopeptidases; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Plasminogen; Protein Binding; Protein Conformation; Protons; Tryptophan; Tyrosine | 1987 |
Human protein S cDNA encodes Phe-16 and Tyr 222 in consensus sequences for the post-translational processing.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA; DNA Restriction Enzymes; Gene Amplification; Genes; Glycoproteins; Humans; Liver; Molecular Sequence Data; Phenylalanine; Protein Processing, Post-Translational; Protein S; Tyrosine | 1987 |
Beta-adrenergic control of brain uptake of large neutral amino acids.
Topics: Amino Acids; Animals; Biological Transport; Brain; Isoleucine; Isoproterenol; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Tryptophan; Tyrosine; Valine | 1988 |
On the mechanism of imipramine's influence in lowering p-hydroxyphenylglycol concentrations in the brain. The role of tyrosine.
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Ethylene Glycols; Imipramine; Male; Methoxyhydroxyphenylglycol; Phenols; Phenylalanine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Time Factors; Tyramine; Tyrosine | 1988 |
Thyrotropin stimulation of lysosomal tyrosine transport in rat FRTL-5 thyroid cells.
Topics: Animals; Biological Transport; Bucladesine; Cell Line; Cholera Toxin; Cyclic AMP; Cycloheximide; Cystine; Dactinomycin; Kinetics; Leucine; Lysosomes; Phenylalanine; Rats; Thyroid Gland; Thyrotropin; Tyrosine | 1988 |
Analysis of the aromatic 1H NMR spectrum of chicken plasminogen kringle 4.
Topics: Amino Acid Sequence; Animals; Cattle; Chickens; Histidine; Humans; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Plasminogen; Sequence Homology, Nucleic Acid; Structure-Activity Relationship; Swine; Tryptophan; Tyrosine | 1988 |
Analysis of the aromatic 1H-NMR spectrum of the kringle 5 domain from human plasminogen. Evidence for a conserved kringle fold.
Topics: Histidine; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Pepsin A; Peptide Fragments; Phenylalanine; Plasminogen; Protein Conformation; Tryptophan; Tyrosine | 1988 |
L-tyrosine is the precursor of PQQ biosynthesis in Hyphomicrobium X.
Topics: Amino Acids; Bacteria; Bacterial Proteins; Coenzymes; Magnetic Resonance Spectroscopy; Phenylalanine; PQQ Cofactor; Quinolones; Tyrosine | 1988 |
Two-dimensional NMR studies of the porcine muscle adenylate kinase.
Topics: Adenylate Kinase; Animals; Magnetic Resonance Spectroscopy; Muscles; Phenylalanine; Phosphotransferases; Protein Conformation; Swine; Tyrosine | 1988 |
Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals: application to activated human neutrophils and to the heme protein leghemoglobin.
Topics: Chromatography, High Pressure Liquid; Free Radicals; Hemeproteins; Humans; Hydroxides; Hydroxyl Radical; Hydroxylation; Leghemoglobin; Neutrophils; Phenylalanine; Tyrosine | 1988 |
Operator mutations of the Escherichia coli aroF gene.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Base Sequence; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Endonucleases; Escherichia coli; Mutation; Phenylalanine; Single-Strand Specific DNA and RNA Endonucleases; Transcription, Genetic; Tyrosine | 1985 |
Regulatory properties of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase isozymes from Candida maltosa.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Candida; Isoenzymes; Kinetics; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1985 |
Evolution of the regulatory isozymes of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase present in the Escherichia coli genealogy.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Biological Evolution; Escherichia coli; Isoenzymes; Phenylalanine; Spirillum; Tryptophan; Tyrosine | 1986 |
Formation of m-tyrosine and o-tyrosine from L-phenylalanine in various tissues of rats.
Topics: Animals; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine; Tyrosine 3-Monooxygenase | 1985 |
Quantification of the importance of individual steps in the control of aromatic amino acid metabolism.
Topics: Amino Acids; Animals; Biological Transport; Elasticity; Kinetics; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase | 1986 |
Dietary problems of phenylketonuria: effect on CNS transmitters and their possible role in behaviour and neuropsychological function.
Topics: Central Nervous System; Dopamine; Humans; Neurotransmitter Agents; Norepinephrine; Phenylalanine; Phenylketonurias; Psychological Tests; Serotonin; Tyrosine | 1986 |
Engineering of the active site of human lysozyme: conversion of aspartic acid 53 to glutamic acid and tyrosine 63 to tryptophan or phenylalanine.
Topics: Amino Acid Sequence; Aspartic Acid; Chitin; Genetic Engineering; Glutamates; Glutamic Acid; Humans; Micrococcus; Muramidase; Mutation; Phenylalanine; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Tyrosine | 1987 |
Assay for tyrosine hydroxylase by high-performance liquid chromatography with fluorescence detection.
Topics: Adrenal Medulla; Animals; Brain; Brain Chemistry; Catalase; Chromatography, High Pressure Liquid; Iron; Levodopa; Male; Phenylalanine; Rats; Spectrometry, Fluorescence; Tyrosine; Tyrosine 3-Monooxygenase | 1987 |
Purification and characterization of a tyrosine aminotransferase from Crithidia fasciculata.
Topics: Animals; Chromatography; Crithidia; Cross Reactions; Electrophoresis, Polyacrylamide Gel; Hydrogen-Ion Concentration; Kinetics; Liver; Mice; Phenylalanine; Substrate Specificity; Temperature; Trypanosoma brucei gambiense; Tryptophan; Tyrosine; Tyrosine Transaminase | 1987 |
Two mutations of dihydropteridine reductase deficiency.
Topics: Dihydropteridine Reductase; Female; Folic Acid; Humans; Infant; Male; Mutation; NADH, NADPH Oxidoreductases; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Pterins; Tyrosine | 1988 |
Enzymic arrangement and allosteric regulation of the aromatic amino acid pathway in Neisseria gonorrhoeae.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Humans; Hydro-Lyases; Neisseria gonorrhoeae; Oxidoreductases; Phenylalanine; Prephenate Dehydrogenase; Transaminases; Tyrosine; Tyrosine Transaminase | 1987 |
Enzymological features of aromatic amino acid biosynthesis reflect the phylogeny of mycoplasmas.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Acholeplasma laidlawii; Allosteric Regulation; Amino Acids; Methionine; Mycoplasma; Phenylalanine; Phylogeny; Tyrosine | 1987 |
[Regulatory effects of terminal products and intermediates of aromatic pathways on rifamycin biosynthesis in Nocardia mediterranei].
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; 4-Aminobenzoic Acid; Aldehyde-Lyases; Nocardia; Parabens; Phenylalanine; Rifamycins; Tryptophan; Tyrosine | 1988 |
Regulation of metabolic branch points of aromatic amino acid biosynthesis in Pichia guilliermondii.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Allosteric Regulation; Amino Acids; Chromatography, DEAE-Cellulose; Phenylalanine; Pichia; Saccharomycetales; Tyrosine | 1988 |
The postprephenate biochemical pathways to phenylalanine and tyrosine: an overview.
Topics: Amino Acids, Dicarboxylic; Bacteria; Cyclohexanecarboxylic Acids; Cyclohexenes; Escherichia coli; Neurospora crassa; Phenylalanine; Tyrosine | 1987 |
Response of natural killer cells from dietary tyrosine- and phenylalanine-restricted mice to biological response modifiers.
Topics: Animals; Antigen-Antibody Complex; Female; Food, Formulated; Immunologic Deficiency Syndromes; Interleukin-2; Killer Cells, Natural; Lymphopenia; Male; Melanoma; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Phenylalanine; Poly I-C; Specific Pathogen-Free Organisms; Tyrosine | 1988 |
A point mutation in the extracellular domain of the human CSF-1 receptor (c-fms proto-oncogene product) activates its transforming potential.
Topics: Animals; Binding, Competitive; Cell Line; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Colony-Stimulating Factors; Humans; Mice; Mutation; Phenylalanine; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogenes; Receptor, Macrophage Colony-Stimulating Factor; Tyrosine | 1988 |
Effect of aspartame on seizures in various models of experimental epilepsy.
Topics: Animals; Aspartame; Brain Chemistry; Dipeptides; Electroshock; Epilepsy; Male; Pentylenetetrazole; Phenylalanine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Spectroscopic characterization of plastocyanin from hornwort.
Topics: Amino Acids; Circular Dichroism; Electron Spin Resonance Spectroscopy; Eukaryota; Phenylalanine; Plant Proteins; Plants; Plastocyanin; Spectrophotometry; Spectrophotometry, Ultraviolet; Tyrosine | 1986 |
Dihydrofolate reductase. 1H resonance assignments and coenzyme-induced conformational changes.
Topics: Amino Acid Sequence; Histidine; Lacticaseibacillus casei; Magnetic Resonance Spectroscopy; Models, Molecular; NADP; Phenylalanine; Protein Conformation; Protons; Tetrahydrofolate Dehydrogenase; Tryptophan; Tyrosine | 1986 |
1H NMR (500 MHz) identification of aromatic residues of gene 32 protein involved in DNA binding by use of protein containing perdeuterated aromatic residues and by site-directed mutagenesis.
Topics: Amino Acid Sequence; Bacterial Proteins; DNA-Binding Proteins; Escherichia coli; Genes; Genes, Bacterial; Histidine; Hydrogen; Magnetic Resonance Spectroscopy; Mutation; Phenylalanine; Tryptophan; Tyrosine | 1986 |
The aromatic 1H-NMR spectrum of plasminogen kringle 4. A comparative study of human, porcine and bovine homologs.
Topics: Animals; Cattle; Histidine; Humans; Magnetic Resonance Spectroscopy; Peptide Fragments; Phenylalanine; Plasminogen; Protons; Species Specificity; Swine; Tryptophan; Tyrosine | 1986 |
Yeast cytochrome c with phenylalanine or tyrosine at position 87 transfers electrons to (zinc cytochrome c peroxidase)+ at a rate ten thousand times that of the serine-87 or glycine-87 variants.
Topics: Cytochrome c Group; Cytochrome-c Peroxidase; Electron Transport; Genetic Variation; Glycine; History, Ancient; Mutation; Peroxidases; Phenylalanine; Saccharomyces cerevisiae; Serine; Structure-Activity Relationship; Tyrosine | 1987 |
Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation.
Topics: Amino Acid Sequence; Bacteriorhodopsins; Base Sequence; Cloning, Molecular; Gene Expression Regulation; Mutation; Phenylalanine; Protein Conformation; Protons; Tyrosine | 1987 |
Tyrosyl-tRNA synthetase from baker's yeast. Order of substrate addition, discrimination of 20 amino acids in aminoacylation of tRNATyr-C-C-A and tRNATyr-C-C-A(3'NH2).
Topics: Acylation; Adenosine Triphosphate; Amino Acids; Amino Acyl-tRNA Synthetases; Binding, Competitive; Escherichia coli; Geobacillus stearothermophilus; Hydrogen Bonding; Isoleucine-tRNA Ligase; Kinetics; Phenylalanine; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Tyr; Saccharomyces cerevisiae; Substrate Specificity; Thermodynamics; Tyrosine; Tyrosine-tRNA Ligase | 1988 |
Sequential metabolic characteristics following portacaval shunt in rats.
Topics: Amino Acids; Animals; Body Weight; Glucagon; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1986 |
Proton nuclear magnetic resonance studies on the kinetics of tryptic fragments of calmodulin upon calcium binding.
Topics: Animals; Calcium; Calmodulin; Kinetics; Lysine; Magnetic Resonance Spectroscopy; Mollusca; Peptide Fragments; Phenylalanine; Protein Conformation; Trypsin; Tyrosine | 1986 |
Metabolic conversion of L-[U-14C]phenylalanine to respiratory 14CO2 in healthy subjects, phenylketonuria heterozygotes and classic phenylketonurics.
Topics: Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Deuterium; Heterozygote; Humans; Hydroxylation; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Structure-function relationships in the free insulin monomer.
Topics: Amino Acid Sequence; Glycine; Histidine; Hydrogen-Ion Concentration; Insulin; Lysine; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Tyrosine | 1986 |
Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Genes; Genetic Vectors; Mice; Mutation; Oncogene Protein pp60(v-src); Peptide Mapping; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Retroviridae; Retroviridae Proteins; Tyrosine | 1987 |
Regulation of the aroH operon of Escherichia coli by the tryptophan repressor.
Topics: Amino Acids; beta-Galactosidase; Cloning, Molecular; Escherichia coli; Gene Expression Regulation; Operon; Phenylalanine; Recombinant Fusion Proteins; Repressor Proteins; Transcription Factors; Tryptophan; Tyrosine | 1987 |
Maternal PKU syndrome in an exceptional family with unexpected PKU.
Topics: Adult; Child, Preschool; Female; Humans; In Vitro Techniques; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1987 |
Primary hypothyroidism in an adult patient with protein-calorie malnutrition: a study of its mechanism and the effect of amino acid deficiency.
Topics: Aged; Amino Acids; Humans; Hypothyroidism; Male; Parenteral Nutrition, Total; Phenylalanine; Protein-Energy Malnutrition; Thyroid Function Tests; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse; Tyrosine | 1988 |
Kinetic and regulatory properties of arogenate dehydratase in seedlings of Sorghum bicolor (L.) Moench.
Topics: Amino Acids, Dicarboxylic; Binding, Competitive; Chromatography, DEAE-Cellulose; Cyclohexenes; Dithiothreitol; Edetic Acid; Enzyme Activation; Glutathione; Hydro-Lyases; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Plants; Tyrosine | 1988 |
Studies on the formation of 3,4-dihydroxyphenylalanine, m-tyrosine and o-tyrosine from L-phenylalanine by rat liver and adrenal.
Topics: Adrenal Glands; Animals; Dihydroxyphenylalanine; Hydroxylation; Liver; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1988 |
Aminoacidopathies: a review of 3 years experience of investigations in a Kuwait hospital.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Child, Preschool; Citrulline; Cystinuria; Female; Glycine; Homocystinuria; Humans; Infant; Infant, Newborn; Kuwait; Male; Maple Syrup Urine Disease; Phenylalanine; Phenylketonurias; Proline; Tyrosine | 1988 |
Abnormal serum phenylalanine-tyrosine ratio and hyperferritinemia in malignant histiocytosis.
Topics: Adolescent; Child; Child, Preschool; Female; Ferritins; Histiocytic Sarcoma; Humans; Infant; L-Lactate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Measles; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pteridines; Tyrosine | 1988 |
Functional domains involved in aromatic amino acid biosynthesis.
Topics: Alcohol Oxidoreductases; Chymotrypsin; Escherichia coli; Hydro-Lyases; Kinetics; Lyases; Molecular Weight; Multienzyme Complexes; Neurospora; Neurospora crassa; Phenylalanine; Phosphotransferases (Alcohol Group Acceptor); Transferases; Trypsin; Tryptophan; Tyrosine | 1985 |
[Reference levels for phenylalanine and tyrosine in discs impregnated with blood during analysis by HPLC].
Topics: Adolescent; Adult; Child; Child Nutrition Disorders; Child, Preschool; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Humans; Infant; Infant Nutrition Disorders; Infant, Newborn; Phenylalanine; Reference Values; Tyrosine | 1988 |
Tyrosine hydrogen-bonding and environmental effects in proteins probed by ultraviolet resonance Raman spectroscopy.
Topics: Animals; Antimicrobial Cationic Peptides; Chemical Phenomena; Chemistry, Physical; Cresols; Egg Proteins; Elapid Venoms; Erabutoxins; Hydrogen Bonding; Ovomucin; Phenylalanine; Plant Proteins; Protein Conformation; Spectrum Analysis, Raman; Thermodynamics; Tyrosine; Ultraviolet Rays | 1988 |
[Plasma amino acid in patients with alcoholic liver diseases--with special reference to the reduce of tyrosine].
Topics: Adult; Alcohol Drinking; Amino Acids; Eating; Female; Humans; Liver Diseases, Alcoholic; Male; Middle Aged; Phenylalanine; Tyrosine | 1988 |
Maternal phenylketonuria: successful outcome in four pregnancies treated prior to conception.
Topics: Child; Child, Preschool; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1988 |
A free-energy perturbation study of the binding of methotrexate to mutants of dihydrofolate reductase.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Computer Simulation; Methotrexate; Mutation; Phenylalanine; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1988 |
Quantitation of interaction between cytochrome P-450scc and adrenodoxin--analysis in the median UV-region by second derivative spectroscopy.
Topics: Adrenodoxin; Animals; Cattle; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Drug Interactions; Ferredoxin-NADP Reductase; Kinetics; Phenylalanine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1988 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
Fidelity of aminoacylation by rat-liver tyrosyl-tRNA synthetase. Effect of age.
Topics: Acylation; Age Factors; Aging; Amino Acids; Amino Acyl-tRNA Synthetases; Animals; Binding Sites; Binding, Competitive; Biological Transport; Electrophoresis, Polyacrylamide Gel; Liver; Male; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred F344; RNA, Transfer; Tyrosine; Tyrosine-tRNA Ligase | 1988 |
UV spectroscopic characterization of type I collagen.
Topics: Animals; Cattle; Collagen; Hot Temperature; Macromolecular Substances; Phenylalanine; Protein Denaturation; Skin; Spectrophotometry, Ultraviolet; Tyrosine | 1988 |
Two new fluorophore pairs, tyrosine-4'-aminophenylalanine and tyrosine-4'-dimethylaminophenylalanine, in the determination of molecular dimensions in peptides.
Topics: Energy Transfer; Fluorescent Dyes; Peptides; Phenylalanine; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tyrosine | 1988 |
Increased concentrations of tyrosine and phenylalanine in the cerebrospinal fluid as a possible reflection of related changes of the brain tissue in newborns with intra-uterine growth retardation.
Topics: Biomarkers; Brain; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Infant, Small for Gestational Age; Phenylalanine; Pregnancy; Reference Values; Tyrosine | 1988 |
Probing the functional role of phenylalanine-31 of Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Amino Acids; Binding Sites; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; Phenylalanine; Plasmids; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1987 |
Genetic separability of the chorismate mutase and prephenate dehydrogenase components of the Escherichia coli tyrA gene product.
Topics: Chorismate Mutase; Culture Media; Escherichia coli; Gene Expression Regulation; Genes, Bacterial; Hydrogen-Ion Concentration; Isomerases; Oxidoreductases; Phenotype; Phenylalanine; Plasmids; Prephenate Dehydrogenase; Tyrosine | 1987 |
Whole body leucine, phenylalanine, and tyrosine kinetics in end-stage liver disease before and after hepatic transplantation.
Topics: Carbon Isotopes; Female; Humans; Kinetics; Leucine; Liver Diseases; Liver Transplantation; Male; Middle Aged; Phenylalanine; Tyrosine | 1987 |
Biochemical and autoradiographic study of cerebral protein synthesis with [18F]-and [14C]fluorophenylalanine.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Fluorine Radioisotopes; Gerbillinae; Nerve Tissue Proteins; p-Fluorophenylalanine; Phenylalanine; Tyrosine | 1988 |
Hyperphenylalaninemia in the hph-1 mouse mutant.
Topics: Aminohydrolases; Animals; Biopterins; Disease Models, Animal; GTP Cyclohydrolase; Half-Life; Male; Metabolic Clearance Rate; Mice; Mice, Mutant Strains; Phenylalanine; Tyrosine | 1988 |
Purification and characterization of an inducible aromatic amino acid-sensitive form of chorismate mutase from Solanum tuberosum L. tubers.
Topics: Amino Acids; Binding, Competitive; Chorismate Mutase; Chromatography; Enzyme Activation; Hydrogen-Ion Concentration; Isoelectric Focusing; Isomerases; Kinetics; Phenylalanine; Plants; Tryptophan; Tyrosine | 1988 |
Raman spectroscopic evaluation of aging and long-wave UV exposure in the guinea pig lens: a possible model for human aging.
Topics: Aging; Animals; Disulfides; Guinea Pigs; Lens, Crystalline; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Sulfhydryl Compounds; Tryptophan; Tyrosine; Ultraviolet Rays | 1988 |
Administration of aspartame potentiates pentylenetetrazole- and fluorothyl-induced seizures in mice.
Topics: Animals; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Drug Synergism; Flurothyl; Male; Mice; Pentylenetetrazole; Phenylalanine; Seizures; Tyrosine | 1988 |
Effect of aging on intestinal absorption of aromatic amino acids in vitro in the rat.
Topics: Aging; Animals; In Vitro Techniques; Intestinal Absorption; Jejunum; Kinetics; Male; Phenylalanine; Rats; Rats, Inbred F344; Tryptophan; Tyrosine | 1988 |
A simplified test to detect PKU heterozygotes by discriminant analysis in mentally retarded children and their mothers.
Topics: Adult; Child; Female; Genetic Carrier Screening; Humans; Male; Models, Genetic; Phenylalanine; Phenylketonurias; Probability; Statistics as Topic; Tyrosine | 1988 |
Binding of recA protein to single- and double-stranded polynucleotides occurs without involvement of its aromatic residues in stacking interactions with nucleotide bases.
Topics: Chemical Phenomena; Chemistry, Physical; DNA; DNA, Single-Stranded; Luminescent Measurements; Magnetic Resonance Spectroscopy; Phenylalanine; Rec A Recombinases; Spectrum Analysis; Structure-Activity Relationship; Tyrosine | 1988 |
Enzymatic determination of L-phenylalanine and phenylpyruvate with L-phenylalanine dehydrogenase.
Topics: Amino Acid Oxidoreductases; Amino Acids; Deamination; Phenylalanine; Phenylpyruvic Acids; Spectrophotometry; Substrate Specificity; Tyrosine | 1988 |
Transport of tyrosine and phenylalanine across the rat nasal mucosa.
Topics: 2,4-Dinitrophenol; Absorption; Animals; Binding, Competitive; Biological Transport; Dinitrophenols; Energy Metabolism; Kinetics; Male; Nasal Mucosa; Ouabain; Perfusion; Phenylalanine; Rats; Rats, Inbred Strains; Sodium; Stereoisomerism; Tyrosine | 1988 |
Inhibition of brain and liver 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase in experimental hyperphenylalaninemia.
Topics: Acyl Coenzyme A; Animals; Animals, Newborn; Body Weight; Brain; Carboxy-Lyases; Chickens; Diet; Liver; Male; Organ Size; Phenylalanine; Tyrosine | 1988 |
Contributions to selective binding of aromatic amino acid residues to tRNA(Phe).
Topics: Amides; Chemical Phenomena; Chemistry; Kinetics; Mathematics; Models, Theoretical; Phenylalanine; RNA, Transfer, Amino Acid-Specific; RNA, Transfer, Phe; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1988 |
About changes of the phenylalanine-tyrosine metabolism in psoriasis vulgaris.
Topics: Adult; Female; Genetic Carrier Screening; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Psoriasis; Tyrosine | 1986 |
Exploratory behavior and the dual activity of some psychoactive drugs: Part II.
Topics: Animals; Exploratory Behavior; Male; Mice; Nicotine; Phenylalanine; Piracetam; Psychotropic Drugs; Pyrrolidines; Tryptophan; Tyrosine; Yohimbine | 1987 |
[Trial of indirect screening of tetrahydrobiopterin deficiency].
Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Humans; Infant; Phenylalanine; Phenylketonurias; Tyrosine | 1987 |
Chloroplasts of higher plants synthesize L-phenylalanine via L-arogenate.
Topics: Allosteric Regulation; Amino Acids, Dicarboxylic; Cell Compartmentation; Chloroplasts; Cyclohexenes; Hydro-Lyases; Kinetics; Phenylalanine; Plants; Temperature; Tyrosine | 1986 |
Dietary restriction of tyrosine and phenylalanine: inhibition of metastasis of three rodent tumors.
Topics: Animals; Diet; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1987 |
Urinary excretion of N-acetyl amino acids in patients with some inborn errors of amino acid metabolism.
Topics: Acetylation; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Gas Chromatography-Mass Spectrometry; Humans; Maple Syrup Urine Disease; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
High-performance liquid chromatography of fluorescent components in serum.
Topics: Chromatography, High Pressure Liquid; Fluorescence; Phenylalanine; Tryptophan; Tyrosine; Uremia | 1987 |
Prenatal diagnosis of "dihydrobiopterin synthetase" deficiency, a variant form of phenylketonuria.
Topics: Alcohol Oxidoreductases; Amniocentesis; Amniotic Fluid; Biopterins; Child, Preschool; Female; Humans; Infant; Male; Neopterin; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pregnancy; Prenatal Diagnosis; Tyrosine | 1986 |
Control of phenylalanine and tyrosine metabolism by phosphorylation mechanisms.
Topics: Animals; Glucagon; In Vitro Techniques; Insulin; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Rats; Rats, Inbred Strains; Spermine; Sympathomimetics; Tyrosine; Vasopressins | 1986 |
Difference in learning and retention by Albino-Swiss mice. Part IV. Effect of some nutrients.
Topics: Amino Acids; Animals; Choline; Diet; Learning; Male; Memory; Mice; Mice, Inbred Strains; Phenylalanine; Phosphatidylserines; Retention, Psychology; Tryptophan; Tyrosine | 1987 |
Phenylalanine and tyrosine in serum and eluates from dried blood spots as determined by reversed-phase liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Isothiocyanates; Paper; Phenylalanine; Quality Control; Thiocyanates; Tyrosine | 1987 |
Phenylalanine requirement of kittens and the sparing effect of tyrosine.
Topics: Animals; Body Weight; Cats; Dietary Proteins; Eating; Female; Male; Nitrogen; Nutritional Requirements; Phenylalanine; Tyrosine | 1987 |
Excessive protein intake: a common cause of false-positive neonatal screening for tyrosinemia.
Topics: Amino Acids; False Positive Reactions; Humans; Infant; Infant Food; Infant, Newborn; Male; Phenylalanine; Tyrosine | 1987 |
Twenty-four-hour variations in rat blood and brain levels of the aromatic and branched-chain amino acids: chronic effects of dietary protein content.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Brain; Circadian Rhythm; Dietary Proteins; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Valine | 1987 |
Studies on the possible role of thyroid hormone in altered muscle protein turnover during sepsis.
Topics: Animals; Carbon Radioisotopes; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains; Sepsis; Thyroidectomy; Triiodothyronine; Tyrosine | 1987 |
Two-dimensional 1H NMR of gene 5 protein indicates that only two aromatic rings interact significantly with oligodeoxynucleotide bases.
Topics: Amino Acid Sequence; DNA-Binding Proteins; Histidine; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Tyrosine | 1987 |
Assignment of the aromatic 1H-NMR resonances of myotoxin a isolated from the venom of Crotalus viridis viridis.
Topics: Animals; Crotalid Venoms; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Snakes; Tyrosine | 1987 |
Raman and infrared spectra of toxin gamma from the venom of the scorpion Tityus serrulatus.
Topics: Animals; Disulfides; Drug Stability; Hydrogen-Ion Concentration; Methionine; Mice; Phenylalanine; Protein Conformation; Scorpion Venoms; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1987 |
Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents. Short note.
Topics: Administration, Oral; Animals; Aspartame; Dipeptides; Humans; Mice; Phenylalanine; Rodentia; Tyrosine | 1987 |
Increased yield of the phenylthiocarbamyl-amino acids tyrosine, cysteine and phenylalanine using diethylether-based liquid-liquid extraction.
Topics: Cysteine; Hydrolysis; Indicators and Reagents; Isothiocyanates; Phenylalanine; Protein Hydrolysates; Thiocyanates; Tyrosine | 1987 |
Interaction between specific dietary factors and experimental chemotherapy of metastatic melanoma.
Topics: Animals; Ascorbic Acid; Diet; Female; Levodopa; Lung Neoplasms; Melanoma; Mice; Mice, Inbred Strains; Phenylalanine; Tyrosine | 1986 |
HPLC assay of phenylalanine and tyrosine in blood spots on filter paper.
Topics: Adult; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Infant, Newborn; Mass Screening; Paper; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Phenylalanine transport at the human blood-brain barrier. Studies with isolated human brain capillaries.
Topics: Adult; Aged; Animals; Biological Transport, Active; Blood-Brain Barrier; Capillaries; Cerebrovascular Circulation; Female; Humans; Kinetics; Male; Mathematics; Middle Aged; Phenylalanine; Rabbits; Tyrosine | 1986 |
In vivo studies on the formation of m-tyrosine and o-tyrosine from L-phenylalanine in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1986 |
Spectroscopic studies of lipoproteins.
Topics: Apolipoproteins; Humans; Lipoproteins; Phenylalanine; Spectrometry, Fluorescence; Spectrophotometry; Tryptophan; Tyrosine | 1986 |
Determination of m-tyrosine and o-tyrosine in human serum by high-performance liquid chromatography with fluorimetric detection.
Topics: Chromatography, High Pressure Liquid; Humans; Phenylalanine; Spectrometry, Fluorescence; Tyrosine | 1986 |
Relative reliability of three different discriminant analysis methods for detecting PKU gene carriers.
Topics: Biometry; Fasting; Genetic Carrier Screening; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Effects of phenylalanine on the release of endogenous dopamine from rat striatal slices.
Topics: Animals; Corpus Striatum; Dopamine; Electric Stimulation; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tetrodotoxin; Tyrosine | 1986 |
A simple method for detection of heterozygous carriers of the gene for classic phenylketonuria.
Topics: Chromatography, High Pressure Liquid; Female; Genetic Carrier Screening; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Impaired phenylalanine-tyrosine conversion in patients with iron-deficiency anemia studied by a L-(2H5)phenylalanine-loading test.
Topics: Adult; Anemia, Hypochromic; Fasting; Female; Genetic Carrier Screening; Humans; Iron; Male; Middle Aged; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1986 |
The NIH-shift in the in vivo hydroxylation of ring-deuterated L-phenylalanine in man.
Topics: Adult; Biotransformation; Deuterium; Genetic Carrier Screening; Humans; Hydroxylation; Isotope Labeling; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
In vitro interactions of opioid peptides with phospholipids. II. Additional spectral evidence.
Topics: Binding Sites; Circular Dichroism; Enkephalin, Leucine; Fluorescence Polarization; Liposomes; Phenylalanine; Phosphatidylserines; Spectrophotometry, Ultraviolet; Tyrosine | 1986 |
[The plasma molar ratio of valine, leucine and isoleucine to phenylalanine and tyrosine as a marker of portal-systemic shunt in liver cirrhosis].
Topics: Adult; Collateral Circulation; Female; Hepatic Encephalopathy; Humans; Isoleucine; Leucine; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Portal System; Portography; Tyrosine; Valine | 1986 |
Discrimination of heterozygotes for phenylketonuria, persistent hyperphenylalaninemia and controls by phenylalanine loading.
Topics: Female; Genetic Carrier Screening; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Regulation of hepatic aromatic amino acid metabolism.
Topics: Biological Transport; Carrier Proteins; Cell Membrane; Liver; Phenylalanine; Tryptophan; Tyrosine | 1986 |
New England Maternal PKU Project: prospective study of untreated and treated pregnancies and their outcomes.
Topics: Adolescent; Adult; Female; Fetal Blood; Fetal Diseases; Humans; Infant, Newborn; Microcephaly; Patient Compliance; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Prognosis; Tyrosine | 1987 |
Hyperphenylalaninemia in Polish children's population.
Topics: Diagnosis, Differential; Humans; Infant, Newborn; Mass Screening; Phenylalanine; Phenylketonurias; Poland; Tyrosine | 1985 |
Modulation of peroxidation in murine melanoma by dietary tyrosine-phenylalanine restriction, levodopa methylester chemotherapy, and sodium ascorbate supplementation.
Topics: Animals; Ascorbic Acid; Diet; Female; Levodopa; Lipid Peroxides; Liver; Malondialdehyde; Melanoma; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenylalanine; Tyrosine | 1985 |
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1985 |
Muscle protein turnover: effects of exercise training and renal insufficiency.
Topics: Alanine; Animals; Body Weight; Carbon Radioisotopes; Female; Insulin; Kidney Failure, Chronic; Muscle Proteins; Muscles; Phenylalanine; Phosphates; Physical Conditioning, Animal; Physical Exertion; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
[Observations on the use of amino-acid mixtures in severe burn patients].
Topics: Adult; Amino Acids; Blood Proteins; Burns; Female; Humans; Male; Middle Aged; Nitrogen; Parenteral Nutrition; Parenteral Nutrition, Total; Phenylalanine; Tyrosine | 1985 |
Identification of peptides containing tryptophan, tyrosine, and phenylalanine using photodiode-array spectrophotometry.
Topics: Apolipoprotein A-I; Apolipoproteins A; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Mathematics; Peptide Fragments; Phenylalanine; Spectrophotometry, Ultraviolet; Trypsin; Tryptophan; Tyrosine | 1985 |
Enzymatic and nonenzymatic dehydration reactions of L-arogenate.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; Hydro-Lyases; Phenylalanine; Pseudomonas; Pseudomonas aeruginosa; Pyrrolidonecarboxylic Acid; Species Specificity; Tyrosine | 1985 |
[Thin-layer chromatographic and fluorometric determination of the ratio of serum free branched chain amino acids to aromatic amino acids].
Topics: Amino Acids, Branched-Chain; Chromatography, Thin Layer; Fluorometry; Hepatitis; Humans; Liver Cirrhosis; Phenylalanine; Tyrosine | 1985 |
Abnormal phenylalanine hydroxylation and tyrosine oxidation in a patient with acute fulminant liver disease with correction by liver transplantation.
Topics: Female; Hepatic Encephalopathy; Hepatitis C; Hepatitis, Viral, Human; Humans; Hydroxylation; Kinetics; Liver Transplantation; Middle Aged; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Postoperative Period; Tyrosine | 1985 |
Biopterin, neopterin and tyrosine responses to combined oral phenylalanine and tetrahydrobiopterin loading tests in two normal children and in a girl with partial biopterin deficiency.
Topics: Administration, Oral; Biopterins; Child; Female; Humans; Neopterin; Phenylalanine; Pteridines; Tyrosine | 1985 |
Outcome of pregnancy in the rat with mild hyperphenylalaninaemia and hypertyrosinaemia: implications for the management of "human maternal PKU".
Topics: Animals; Brain Diseases; Discrimination, Psychological; Disease Models, Animal; Female; Motor Activity; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Space Perception; Tyrosine | 1985 |
Immobilization decreases amino acid concentrations in plasma but maintains or increases them in brain.
Topics: Amino Acids; Animals; Brain Chemistry; Humans; Immobilization; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Valine | 1986 |
Transport of the aromatic amino acids into isolated rat liver cells. Properties of uptake by two distinct systems.
Topics: Amino Acids; Amino Acids, Cyclic; Animals; Biological Transport; Cell Membrane; In Vitro Techniques; Kinetics; Leucine; Liver; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1986 |
NOE data at 500 MHz reveal the proximity of phenyl and tyrosine rings in enkephalin.
Topics: Enkephalins; Glycine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Phenylalanine; Protein Conformation; Tyrosine | 1986 |
The effect of enzymatic reaction on dissolution rate: theoretical analysis and experimental test.
Topics: Diffusion; Enzymes; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Phenylalanine; Solubility; Tyrosine; Viscosity | 1986 |
The effect of a phenylalanine and tyrosine restricted diet on elemental balance studies and plasma aminograms of patients with disseminated malignant melanoma.
Topics: Adult; Amino Acids; Elements; Female; Food, Formulated; Humans; Male; Melanoma; Middle Aged; Patient Compliance; Phenylalanine; Tyrosine | 1985 |
Cocaine and phencyclidine. Heterogenous dopaminergic interactions with tetrabenazine.
Topics: Amphetamine; Animals; Cocaine; Dopamine; Drug Interactions; In Vitro Techniques; Mitochondria; Nalidixic Acid; Naphthyridines; Phencyclidine; Phenylalanine; Rats; Receptors, Dopamine; Reserpine; Synaptosomes; Tetrabenazine; Tyrosine | 1985 |
Amino acid and protein requirements in a preterm infant with classic phenylketonuria.
Topics: Amino Acids; Body Weight; Dietary Proteins; Female; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Nutritional Requirements; Phenylalanine; Phenylketonurias; Tyrosine | 1985 |
L-Phenylalanine and L-tyrosine catabolism by selected Streptomyces species.
Topics: Phenylalanine; Streptomyces; Tyrosine | 1985 |
Oral versus intravenous L-phenylalanine loading compared by simultaneous application of L-[2H5] and L-[15N]phenylalanine.
Topics: Administration, Oral; Adult; Deuterium; Female; Humans; Infusions, Parenteral; Kinetics; Male; Nitrogen Isotopes; Phenylalanine; Tyrosine | 1985 |
The metabolism of L-phenylalanine and L-tyrosine by liver cells isolated from adrenalectomized rats and from streptozotocin-diabetic rats.
Topics: Acute Disease; Adrenalectomy; Animals; Chronic Disease; Dexamethasone; Diabetes Mellitus, Experimental; In Vitro Techniques; Liver; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1985 |
Relationship between phenylalanine tolerance and psychological characteristics of phenylketonuric families.
Topics: Adolescent; Adult; Analysis of Variance; Child; Female; Heterozygote; Homozygote; Humans; Intelligence Tests; Male; Personality Tests; Phenylalanine; Phenylketonurias; Tyrosine | 1985 |
Synthesis and biological activities of analogues of angiotensins II and III containing O-methyltyrosine and D-tryptophan.
Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Female; In Vitro Techniques; Phenylalanine; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Structure-Activity Relationship; Tryptophan; Tyrosine; Uterus | 1985 |
Maternal PKU.
Topics: Birth Weight; Female; Fetal Blood; Humans; Infant, Newborn; Intelligence; Mass Screening; Maternal-Fetal Exchange; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1985 |
The effect of pyridoxine deficiency on the metabolism of the aromatic amino acids by isolated rat liver cells.
Topics: Amino Acids; Aminooxyacetic Acid; Animals; Dietary Proteins; Hydrolases; Liver; Male; Mathematics; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase; Tyrosine; Vitamin B 6 Deficiency | 1985 |
Physical studies by NMR and circular dichroism determining three structurally different domains in Physarum polycephalum histone H1.
Topics: Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; DNA; Fungal Proteins; Histidine; Histones; Magnetic Resonance Spectroscopy; Peptide Fragments; Phenylalanine; Physarum; Protein Binding; Species Specificity; Thermodynamics; Trypsin; Tyrosine | 1985 |
Partial purification and some properties of tryptophan decarboxylase from a Bacillus strain.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Bacillus; Chromatography, Ion Exchange; Enzyme Induction; Hydrogen-Ion Concentration; Phenylalanine; Sonication; Temperature; Tryptamines; Tryptophan; Tyrosine | 1985 |
Effect of cocaine dependence on plasma phenylalanine and tyrosine levels and on urinary MHPG excretion.
Topics: Adult; Cocaine; Female; Glycols; Humans; Male; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Phenylalanine; Substance-Related Disorders; Tyrosine | 1985 |
Preliminary report on inverse diurnal variation of phenylalanine: implications in maternal phenylketonuria.
Topics: Adult; Amino Acids; Circadian Rhythm; Female; Fetal Diseases; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1985 |
Effects of phenylalanine and analogues of methionine and phenylalanine on the composition of wool and mouse hair.
Topics: Amino Acids; Animals; Female; Hair; Male; Methoxamine; Mice; Molecular Weight; Orchiectomy; Phenylalanine; Proteins; Sheep; Species Specificity; Sulfur; Tyrosine; Wool | 1985 |
Discrimination of phenylketonurics from persistent hyperphenylalaninemia patients using a simple phenylalanine loading test.
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Female; Humans; Male; Phenylalanine; Phenylketonurias; Statistics as Topic; Tyrosine | 1985 |
Computer-implemented nutrition support of phenylketonuria.
Topics: Dietetics; Energy Intake; Humans; Infant; Infant Food; Microcomputers; Phenylalanine; Phenylketonurias; Tyrosine | 1985 |
Evolutionary implications of features of aromatic amino acid biosynthesis in the genus Acinetobacter.
Topics: Acinetobacter; Biological Evolution; Kinetics; Phenylalanine; Phylogeny; Species Specificity; Tyrosine | 1985 |
Antinociceptive effect of some carboxypeptidase A inhibitors in comparison with D-phenylalanine.
Topics: Analgesics; Animals; Carboxypeptidases; Carboxypeptidases A; Female; Hypnotics and Sedatives; Indoleacetic Acids; Mice; Phenylalanine; Phenylpropionates; Time Factors; Tyrosine | 1985 |
Copper(II) and nickel(II) ternary complexes of L-dopa and related compounds.
Topics: Chemical Phenomena; Chemistry; Copper; Dopamine; Hydrogen-Ion Concentration; Kinetics; Levodopa; Ligands; Nickel; Osmolar Concentration; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1985 |
Interconvertible molecular-weight forms of the bifunctional chorismate mutase-prephenate dehydratase from Acinetobacter calcoaceticus.
Topics: Acinetobacter; Allosteric Regulation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Activation; Hydro-Lyases; Kinetics; Molecular Weight; Phenylalanine; Prephenate Dehydratase; Tyrosine | 1985 |
Acidic metabolites of phenylalanine in plasma of phenylketonurics.
Topics: Adolescent; Adult; Amino Acids; Child; Child, Preschool; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; Infant; Phenylalanine; Phenylketonurias; Tyrosine | 1985 |
Aromatic amino acid requirement of the lactating sow.
Topics: Animal Nutritional Physiological Phenomena; Animals; Female; Lactation; Phenylalanine; Pregnancy; Swine; Tyrosine | 1985 |
Spectrophotometric determination of some peptidases.
Topics: Amino Acid Oxidoreductases; Isoleucine; Leucine; Methionine; Methods; Microchemistry; NAD; Peptide Hydrolases; Peroxidases; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
Histochemical significance of green metachromasia to toluidine blue.
Topics: Calcium Chloride; Glycosaminoglycans; Histocytochemistry; Iron; Phenols; Phenylalanine; Staining and Labeling; Toluene; Tryptophan; Tyrosine | 1970 |
Corticosteroid induced changes in plasma amino acids and thyroid activity in dairy cows treated early or late during lactation.
Topics: Adrenal Cortex Hormones; Amino Acids; Animals; Body Weight; Cattle; Dexamethasone; Female; Flumethasone; Glutamine; Glycerol; Iodine; Isoleucine; Lactation; Methionine; Phenylalanine; Pregnancy; Serine; Thyroid Function Tests; Thyroid Gland; Tyrosine; Urea; Valine | 1971 |
[Physical chemical properties of component II of duck lysosomes].
Topics: Amino Acid Sequence; Animals; Binding Sites; Chemical Phenomena; Chemistry, Physical; Chickens; Diffusion; Ducks; Glucosamine; Hot Temperature; Hydrogen-Ion Concentration; Lysosomes; Muramidase; Optical Rotatory Dispersion; Phenylalanine; Protein Denaturation; Species Specificity; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
Fluorometry of a DOPA peptide and its thioether.
Topics: Carbon Isotopes; Catechol Oxidase; Catechols; Chromatography, Paper; Cysteine; Dihydroxyphenylalanine; Dipeptides; Ethers; Fluorescence; Fluorometry; Melanoma; Peptides; Phenylalanine; Pigments, Biological; Spectrophotometry; Sulfhydryl Reagents; Sulfur; Tyrosine | 1971 |
Quantitative investigation of the hippuric acid formation in the rat after administration of some possible aromatic and hydroaromatic precursors.
Topics: Aldehydes; Animals; Benzoates; Benzyl Compounds; Chromatography, Thin Layer; Cinnamates; Cyclohexanecarboxylic Acids; Cyclohexanes; Female; Glycine; Hippurates; Phenylacetates; Phenylalanine; Propionates; Quinic Acid; Rats; Salicylates; Shikimic Acid; Tyrosine | 1971 |
Genetic control of the immune response. Relationship between the immune response-1 gene(s) and individual H-2 antigenic specificities.
Topics: Alleles; Animals; Epitopes; Female; Genes; Genetic Linkage; Glutamates; Histidine; Histocompatibility; Immunogenetics; Male; Mice; Phenylalanine; Tyrosine | 1972 |
Contribution of different cell types to the genetic control of immune responses as a function of the chemical nature of the polymeric side chains (poly-L-prolyl and poly-DL-alanyl) of synthetic immunogens.
Topics: Alanine; Animals; Antibody-Producing Cells; Antigens; Bone Marrow; Bone Marrow Cells; Epitopes; Erythrocytes; Female; Glutamine; Hemagglutination Tests; Immunogenetics; Lysine; Male; Methods; Mice; Mice, Inbred Strains; Peptides; Phenylalanine; Polymers; Proline; Sheep; Spleen; Thymus Gland; Tyrosine | 1972 |
Nature of the molecular defect in phenylketonuria and hyperphenylalaninaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Carbon Isotopes; Epitopes; Genes; Genes, Regulator; Humans; Immunodiffusion; Kinetics; Liver; Lysophosphatidylcholines; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Sheep; Tyrosine | 1972 |
Effect of co-trimoxazole on phenylalanine metabolism in man.
Topics: Animals; Anti-Infective Agents; Chromatography, Ion Exchange; Colorimetry; Drug Synergism; Fasting; Folic Acid Antagonists; Humans; Mammals; Phenylalanine; Phenylalanine Hydroxylase; Pyrimidines; Sulfamethoxazole; Time Factors; Trimethoprim; Tyrosine | 1972 |
Uptake of amino acids and nucleic acid precursors by regenerating rat liver.
Topics: Adenine; Adrenalectomy; Amino Acids; Animals; Dactinomycin; Hepatectomy; Liver; Liver Regeneration; Lysine; Male; Ornithine; Orotic Acid; Phenylalanine; Rats; RNA; Thymidine; Tritium; Tyrosine; Uridine; Valine | 1972 |
Cooperation of antigenic determinants in intact mice and interference by antigenic competition.
Topics: Alanine; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Carrier Proteins; Epitopes; Glutamates; Hemagglutination Tests; Lysine; Mice; Mice, Inbred C3H; Peptides; Phenylalanine; Proline; Tyrosine | 1972 |
Aminoacid composition of amniotic fluid in central-nervous-system malformations.
Topics: Amino Acids; Amniocentesis; Amniotic Fluid; Anencephaly; Female; Fetal Death; Humans; Infant, Newborn; Isoleucine; Leucine; Methionine; Phenylalanine; Pregnancy; Respiratory Distress Syndrome, Newborn; Spinal Dysraphism; Tyrosine | 1973 |
[Method of detection of heterozygotic carrier state in phenylketonuria].
Topics: Adult; Child; Genetic Counseling; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
Charcoal haemoperfusion in the treatment of fulminant hepatic failure.
Topics: Adolescent; Adult; Amino Acids; Autopsy; Biopsy, Needle; Blood; Blood Cell Count; Blood Coagulation; Blood Platelets; Blood Specimen Collection; Charcoal; Female; Halothane; Hepatic Encephalopathy; Humans; Liver; Liver Diseases; Liver Function Tests; Male; Methionine; Methods; Middle Aged; Perfusion; Phenylalanine; Tyrosine | 1974 |
Effect of adrenergic reactive drugs on Tetrahymena pyriformis in a chemically defined medium.
Topics: Adrenergic beta-Antagonists; Carbon Isotopes; Culture Media; Dihydroxyphenylalanine; Dopamine; Glucose; Glycogen; Isoproterenol; Norepinephrine; Phenylalanine; Propranolol; Reserpine; Tetrahymena pyriformis; Tyrosine | 1972 |
Transamination of ring-substituted L-phenylalanines by an extract from rat liver mitochondria.
Topics: Animals; Autoanalysis; Carbon Isotopes; Cytosol; Female; Fenclonine; Fluorine; Glutamates; Glutarates; Isomerism; Liver; Mitochondria, Liver; Phenylalanine; Rats; Time Factors; Tyrosine; Tyrosine Transaminase | 1973 |
[Regulation of aromatic amino acid biosynthesis in streptomycetes].
Topics: Aldehyde-Lyases; Chloramphenicol; Enzyme Induction; Enzyme Repression; Heptoses; Phenylalanine; Phosphates; Streptomyces; Tryptophan; Tyrosine | 1972 |
[The effect of L-2,5-dihydrophenylalanine].
Topics: Aldehyde-Lyases; Anti-Bacterial Agents; Bacterial Proteins; Binding, Competitive; Cyclohexanecarboxylic Acids; Escherichia coli; Feedback; Fluorine; Heptoses; Isoenzymes; Microbial Sensitivity Tests; Oxidoreductases; Phenylalanine; Phosphoenolpyruvate; Protein Biosynthesis; Pyruvates; Tetroses; Tryptophan; Tyrosine | 1972 |
Tetrahydropterin oxidation without hydroxylation catalyzed by rat liver phenylalanine hydroxylase.
Topics: Animals; Azides; Carbon Isotopes; Catalase; Catalysis; Chymotrypsin; Free Radicals; Hydroxylation; Kinetics; Liver; Lysophosphatidylcholines; NADP; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxidases; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Pyruvates; Rats; Sodium; Stereoisomerism; Tyrosine; Uncoupling Agents | 1973 |
Formation of catecholamines from phenylalanine in brain--effects of chlorpromazine and catron.
Topics: Animals; Brain; Brain Stem; Carbon Isotopes; Catecholamines; Caudate Nucleus; Cerebral Ventricles; Chlorpromazine; Chromatography, Ion Exchange; Female; Fluorometry; Hydrazines; Hydroxylation; Hypothalamus; In Vitro Techniques; Injections; Phenylalanine; Rats; Tritium; Tyrosine; Tyrosine 3-Monooxygenase | 1973 |
tyrR, a regulatory gene of tyrosine biosynthesis in Salmonella typhimurium.
Topics: Aldehyde-Lyases; Cell-Free System; Chromosome Mapping; Conjugation, Genetic; Cyclohexanecarboxylic Acids; Enzyme Repression; Fluorine; Genes; Genes, Regulator; Genetic Linkage; Oxidoreductases; Phenylalanine; Phosphotransferases; Pyruvates; Recombination, Genetic; Salmonella typhimurium; Stereoisomerism; Transduction, Genetic; Tyrosine; Tyrosine Transaminase | 1973 |
Aromatic amino acid metabolism in brindled (Mobr) and viable-brindled (Movbr), two alleles at the mottled locus in the mouse.
Topics: Alleles; Animals; Brain; Dopamine; Enzyme Induction; Female; Genetic Linkage; Hydrocortisone; Liver; Male; Mice; Mutation; Myocardium; Norepinephrine; Phenylalanine; Phenylalanine Hydroxylase; Serotonin; Sex Chromosomes; Spleen; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase | 1972 |
Radiochemical determination of the optical purity of L-amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Carbon Radioisotopes; Catalase; D-Amino-Acid Oxidase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Leucine; Methionine; Phenylalanine; Selenium; Serine; Stereoisomerism; Tritium; Tyrosine; Valine | 1974 |
Futher studies on the nature of phenylalanine hydroxylation in brain.
Topics: Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Chromatography, Thin Layer; Female; Hydroxylation; Liver; Methods; Monoiodotyrosine; Phenylalanine; Phenylalanine Hydroxylase; Propylene Glycols; Pteridines; Rats; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
The stimulation of partially purified bovine caudate tyrosine hydroxylase by phosphatidyl-L-serine.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Cattle; Caudate Nucleus; Chromatography, Thin Layer; Drug Stability; Enzyme Activation; Hydrogen-Ion Concentration; Isotope Labeling; Kinetics; Phenylalanine; Phosphatidylethanolamines; Phosphatidylserines; Protein Binding; Pterins; Solubility; Tritium; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
Studies on the transport of L-tyrosine into an adrenergic clone of mouse neuroblastoma.
Topics: Amino Acids; Animals; Azides; Benzenesulfonates; Biological Transport; Carbon Radioisotopes; Cell Count; Cell Line; Chloromercuribenzoates; Chromatography, Thin Layer; Clone Cells; Dinitrophenols; Electrophoresis, Paper; Glioma; Isomerism; Kinetics; Mice; Neoplasms, Experimental; Neuroblastoma; Osmolar Concentration; Ouabain; Phenylalanine; Time Factors; Tyrosine; Tyrosine 3-Monooxygenase | 1974 |
A new biosynthetic pathway to catecholamines via m-tyrosine.
Topics: Adrenal Glands; Animals; Benzyl Compounds; Brain; Carbon Radioisotopes; Catalysis; Catecholamines; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Iron; Liver; Methyldopa; Methyltyrosines; Mice; Monoiodotyrosine; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phosphates; Pterins; Rats; Structure-Activity Relationship; Tyrosine | 1974 |
A third allele at the phenylalanine-hydroxylase locus in mild phenylketonuria (hyperphenylalaninaemia).
Topics: Adult; Alleles; Antipyrine; Child; Female; Genetic Code; Heterozygote; Humans; Kinetics; Male; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
[Studies on the question of the immune globulin synthesis by human lymphocytes stimulated in vitro by phytohemagglutinin. II. Radiochemical studies].
Topics: Aspergillus; Blood Proteins; Carbon Isotopes; Carboxypeptidases; Chromatography, Thin Layer; Chymotrypsin; Culture Techniques; Freezing; gamma-Globulins; Humans; Hydrolases; Lectins; Leucine; Lymphocytes; Phenylalanine; Radiochemistry; Tissue Extracts; Trichloroacetic Acid; Tritium; Tyrosine; Urea | 1968 |
The chemical composition of wool. 7. Separation and analysis of orthocortex and paracortex.
Topics: Amino Acids; Animals; Cell Membrane; Centrifugation, Density Gradient; Cysteine; Cystine; Glycine; Gold; Leucine; Methods; Microscopy, Electron; Phenylalanine; Sheep; Staining and Labeling; Tyrosine; Ultrasonics; Wool | 1968 |
Protein nutrition of "Tenebrio molitor" L. X. Improvement of the nutritional value of lactalbumin by supplementation with amino acids.
Topics: Albumins; Amino Acids; Animals; Arginine; Body Weight; Caseins; Coleoptera; Dietary Proteins; Nutritional Physiological Phenomena; Phenylalanine; Proline; Tyrosine | 1969 |
Children of mothers with phenylketonuria.
Topics: Adolescent; Adult; Child; Child, Preschool; Diet Therapy; Family Planning Services; Female; Growth Disorders; Heart Defects, Congenital; Heterozygote; Homozygote; Humans; Intellectual Disability; Male; Microcephaly; Middle Aged; Phenylalanine; Phenylketonurias; Seizures; Strabismus; Tyrosine | 1970 |
Platelet reactions and immune processes. 3. The inhibition of platelet aggregation by chymotrypsin substrates and inhibitors.
Topics: Amino Acids; Benzoates; Blood Platelets; Chymotrypsin; Cinnamates; Collagen; Cyclohexanes; Epinephrine; Esterases; Histamine Release; Humans; Isoquinolines; Latex; Lysine; Microspheres; Phenols; Phenylacetates; Phenylalanine; Platelet Adhesiveness; Quinolines; Tryptophan; Tyrosine | 1970 |
Chorismate mutase from Streptomyces aureofaciens: a heat-stable enzyme.
Topics: Cell-Free System; Centrifugation, Density Gradient; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; Cyclohexanes; Feedback; Hot Temperature; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; Molecular Weight; Multienzyme Complexes; ortho-Aminobenzoates; Oxidoreductases; Phenylalanine; Protein Denaturation; Pyruvates; Stereoisomerism; Streptomyces; Streptomyces aureofaciens; Transaminases; Tryptophan; Tyrosine; Vinyl Compounds | 1973 |
The conversion of phenylalanine to tyrosine in Tetrahymena pyriformis.
Topics: Acetates; Animals; Carbon Isotopes; Cell-Free System; Chromatography, Paper; Culture Media; Glucose; Guanine Nucleotides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Spectrophotometry; Stereoisomerism; Tetrahymena pyriformis; Tritium; Tyrosine | 1973 |
[Diagnostic methods for the detection of amino acid metabolism disorders].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Bacillus subtilis; Blood Protein Electrophoresis; Chemistry, Clinical; Chromatography; Clinical Enzyme Tests; Colorimetry; Fluorometry; Histidine; Humans; Leucine; Mass Screening; Metabolic Diseases; Methionine; Methods; Microbial Sensitivity Tests; Organization and Administration; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
The effect of feeding -2-thienylalanine on phenylalanine metabolism in the rhesus monkey.
Topics: Alanine; Animals; Animals, Newborn; Body Height; Body Weight; Brain; Cephalometry; Depression, Chemical; Feeding Behavior; Haplorhini; Humans; Macaca; Phenylalanine; Phenylketonurias; Thiophenes; Tyrosine | 1973 |
A bifunctional enzyme in Pseudomonas aeruginosa: a new pattern in the organization of enzymes concerned with phenylalanine and tyrosine biosynthesis.
Topics: Cell-Free System; Centrifugation, Density Gradient; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclohexanecarboxylic Acids; Cyclohexanes; Hydro-Lyases; Hydroxyapatites; Isoenzymes; Mutation; Oxidoreductases; Phenylalanine; Phosphotransferases; Pseudomonas aeruginosa; Pyruvates; Tyrosine | 1973 |
Specificity of the tyrosine-phenylalanine transport system in Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Binding Sites; Biological Transport, Active; Carbon Isotopes; Ketones; Phenylalanine; Stereoisomerism; Temperature; Tyrosine | 1973 |
Amino acid adequacy of parenteral casein hydrolysate and oral cottage cheese in patients with gastrointestinal disease as measured by nitrogen balance and blood aminogram.
Topics: Amino Acids; Caseins; Dietary Proteins; Gastrointestinal Diseases; Humans; Liver Cirrhosis; Lysine; Methods; Milk Proteins; Nitrogen; Parenteral Nutrition; Phenylalanine; Protein Hydrolysates; Time Factors; Tyrosine; Valine | 1973 |
Growth inhibition by L-phenylalanine in Agmenellum quadruplicatum. A clue to some amino acid interrelationships.
Topics: Alanine; Aldehyde-Lyases; Amino Acids; Culture Media; Cyanobacteria; Heptoses; Isoleucine; Leucine; Methionine; Mutation; Phenylalanine; Phenylpyruvic Acids; Stereoisomerism; Tetroses; Time Factors; Tryptophan; Tyrosine | 1973 |
Gene-enzyme relationships of aromatic acid biosynthesis in Bacillus subtilis.
Topics: Alcohol Oxidoreductases; Aldehyde-Lyases; Bacillus subtilis; Cell-Free System; Chromosome Mapping; Genes; Hydro-Lyases; Lyases; Mutagens; Mutation; Nitrosoguanidines; Phenylalanine; Phosphotransferases; Transaminases; Transduction, Genetic; Transferases; Transformation, Genetic; Tryptophan; Tyrosine; Ultraviolet Rays | 1973 |
Effect of aspartame on phenylalanine metabolism in the monkey.
Topics: Animals; Aspartic Acid; Blood Chemical Analysis; Blood Proteins; Carbon Dioxide; Carbon Radioisotopes; Dipeptides; Female; Haplorhini; Macaca; Phenylalanine; Respiration; Sweetening Agents; Time Factors; Tyrosine | 1973 |
Regulation of phenylalanine biosynthesis in Pseudomonas aeruginosa.
Topics: Chromatography, DEAE-Cellulose; Chromatography, Paper; Cyclohexanecarboxylic Acids; Cyclohexanes; Hydro-Lyases; Isomerases; Kinetics; Multienzyme Complexes; Phenylalanine; Pseudomonas aeruginosa; Pyruvates; Species Specificity; Spectrophotometry, Ultraviolet; Transaminases; Tyrosine; Vinyl Compounds | 1973 |
Accumulation of histidine, 3-methylhistidine, and homocarnosine in the brains of protein-calorie deficient monkeys.
Topics: Amino Acids; Aminobutyrates; Animals; Blood Proteins; Brain; Dietary Proteins; Dipeptides; Female; Glutamates; Haplorhini; Histidine; Lysine; Macaca; Male; Methylhistidines; Phenylalanine; Phosphatidylcholines; Protein-Energy Malnutrition; Serum Albumin; Tyrosine | 1973 |
Learning in monkeys fed elevated amino acid diets.
Topics: Alanine; Amino Acids; Animals; Diet; Discrimination Learning; Female; Food; Glycine; Haplorhini; Histidine; Humans; Learning; Macaca; Monkey Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Problem Solving; Reward; Tryptophan; Tyrosine | 1973 |
Blue-green bacteria synthesise L-tyrosine by the pretyrosine pathway.
Topics: Cyanobacteria; Cyclohexanes; Enzyme Precursors; Hydro-Lyases; Oxidoreductases; Phenylalanine; Protein Precursors; Pyruvates; Transaminases; Tyrosine | 1974 |
Absorption of amino acids in malnourished rats.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Biological Transport; Carbon Radioisotopes; Glycine; Hypoproteinemia; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Lysine; Male; Perfusion; Phenylalanine; Protein Deficiency; Protein-Energy Malnutrition; Rats; Tritium; Tyrosine | 1974 |
Genes and isoenzymes controlling the first step in the aromatic amino acid biosynthesis in Schizosaccharomyces pombe.
Topics: Aldehyde-Lyases; Ascomycota; Chromatography, Gel; Cobalt; Crosses, Genetic; Edetic Acid; Enzyme Induction; Genes; Genetic Linkage; Heptoses; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Manganese; Mutation; Phenylalanine; Phosphoenolpyruvate; Spores, Fungal; Tetroses; Tryptophan; Tyrosine | 1974 |
Comparative biochemistry of p-hydroxymethyl-L-phenylalanine: in vivo studies.
Topics: Animals; Carbon Radioisotopes; Cell Division; Escherichia coli; Hydroxylation; Isomerism; Lacticaseibacillus casei; Lactobacillus; Liver; Male; Methylation; Organ Specificity; Pancreas; Phenylalanine; Rats; Species Specificity; Spectrophotometry; Time Factors; Tritium; Tyrosine | 1974 |
L-leucyl-and L-phenylalanyl-beta-naphthylamidase activities in the tissues of the sea mussel (Mytilus edulis L.).
Topics: Alanine; Amidohydrolases; Animals; Bivalvia; Chloromercuribenzoates; Citrates; Digestive System; Edetic Acid; Electrophoresis; Gills; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Leucine; Mercaptoethanol; Methionine; Muscles; Naphthols; Organ Specificity; Phenylalanine; Sodium; Structure-Activity Relationship; Tyrosine; Urea | 1974 |
Production of L-phenylalanine by DL-phenylalanine hydroxamate-resistant Tyr- mutants of Bacillus subtilis.
Topics: Bacillus subtilis; Cell Division; Chromatography, Paper; Drug Resistance, Microbial; Hydroxamic Acids; Mutation; Phenylalanine; Species Specificity; Time Factors; Tryptophan; Tyrosine | 1974 |
Mis-regulation of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase does not account for growth inhibition by phenylalanine in Agmenellum quadruplicatum.
Topics: Amino Acid Isomerases; Cell-Free System; Cyanobacteria; Enzyme Repression; Feedback; Hydro-Lyases; Ligases; Mutation; Phenylalanine; Phenylpyruvic Acids; Stereoisomerism; Transaminases; Tryptophan; Tyrosine | 1974 |
The potential of coenzyme Q 10 (NSC-140865) in cancer treatment.
Topics: Animals; Antibody Formation; Antineoplastic Agents; Chick Embryo; Cricetinae; Haplorhini; Humans; Lipid Metabolism; Metabolism, Inborn Errors; Mice; Neoplasms; Peroxides; Phenylalanine; Rabbits; Rats; Sarcoma 180; Succinate Dehydrogenase; Turkeys; Tyrosine; Ubiquinone | 1974 |
[Histochemical evidence of aminotransferases. I. Method of histochemical demonstration of a few aminotransferases in rat organs (author's transl)].
Topics: Alanine; Animals; Asparagine; Dihydrolipoamide Dehydrogenase; Electron Transport; Glutamate Dehydrogenase; Glutamates; Glycine; Histocytochemistry; Isoleucine; Ketoglutaric Acids; Kidney; Leucine; Liver; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1974 |
[Experimental findings and new aspects in extrapyramidal diseases].
Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Monoamine Oxidase Inhibitors; Movement Disorders; Norepinephrine; Parkinson Disease; Perphenazine; Phenylalanine; Reserpine; Serotonin; Tyrosine | 1966 |
[Female patient with a hebephrenic course of schizophrenia and later diagnosed phenylketonuria].
Topics: Adult; Amino Acids; Diagnosis, Differential; Female; Humans; Pedigree; Phenylalanine; Phenylketonurias; Schizophrenia; Time Factors; Tyrosine | 1969 |
Purification and properties of 5-hydroxytryptophan decarboxylase from monkey small intestine.
Topics: 5-Hydroxytryptophan; Amines; Animals; Aspartic Acid; Benzoates; Carboxy-Lyases; Edetic Acid; Glutamates; Glutathione; Haplorhini; Histidine; Intestine, Small; Keto Acids; Kinetics; Male; Mercaptoethanol; Metals; Phenylalanine; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1970 |
[Active storage of tryptophan in the isolated rat cerebral cortex].
Topics: Animals; Biological Transport, Active; Cerebral Cortex; Female; In Vitro Techniques; Kinetics; Male; Phenylalanine; Rats; Sodium; Tryptophan; Tyrosine | 1970 |
Interaction of heavy meromyosin with substrate. IV. Studies on the tyrosine and tryptophan residues by solvent perturbation method.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Deuterium; Esters; Glycerol; Glycols; Methods; Muscle Proteins; Optical Rotatory Dispersion; Phenylalanine; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Effect of nitroarginine on phenylalanine under acid hydrolytic conditions.
Topics: Amino Acids; Arginine; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Gas; Fenclonine; Hydrochloric Acid; Hydrogen-Ion Concentration; Hydrolysis; Mass Spectrometry; Methionine; Nitrates; Nitro Compounds; Peptides; Phenylalanine; Tryptophan; Tyrosine | 1971 |
Serum levels of phenylalanine and tyrosine in Huntington's chorea.
Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Body Weight; Dopamine; Female; Humans; Huntington Disease; Male; Middle Aged; Norepinephrine; Parasympatholytics; Phenylalanine; Psychotic Disorders; Reserpine; Schizophrenia; Tryptophan; Tyrosine | 1971 |
Resolution of ring-substituted phenylalanines by the action of alpha-chymotrypsin on their ethyl esters.
Topics: Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Dihydroxyphenylalanine; Esters; Ethanol; Fenclonine; Fluorine; Hydrolysis; Ion Exchange Resins; Kinetics; Phenylalanine; Stereoisomerism; Tyrosine | 1971 |
Effects of oral administration of p-chlorophenylalanine to experimental animals.
Topics: Animals; Body Weight; Brain Chemistry; Diet; Fenclonine; Liver; Male; Organ Size; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine | 1970 |
The influence of catecholamines and related substances on human myocardial (Na +, K + )-ATPase.
Topics: Adenosine Triphosphatases; Catecholamines; Dihydroxyphenylalanine; Dopamine; Epinephrine; Heart; Humans; Kinetics; Mandelic Acids; Microsomes; Myocardium; Norepinephrine; Normetanephrine; Osmolar Concentration; Phenylalanine; Potassium; Sodium; Tyramine; Tyrosine; Vanilmandelic Acid | 1970 |
Hydroxylation of phenylalanine by various areas of brain in vitro.
Topics: Animals; Brain; Brain Stem; Carbon Isotopes; Catecholamines; Caudate Nucleus; Fenclonine; Hydroxylation; Hypothalamus; Lung; Methyltyrosines; Phenylalanine; Phenylalanine Hydroxylase; Pineal Gland; Pteridines; Rats; Spleen; Thalamus; Tyrosine | 1972 |
Behavioral and biochemical effects of p-chlorophenylalanine, 3-chlorotyrosine and 3-chlorotyramine. A proposed mechanism for inhibition of self-stimulation.
Topics: Analysis of Variance; Animals; Behavior, Animal; Brain Chemistry; Chlorine; Depression, Chemical; Dogs; Electric Stimulation; Electrodes, Implanted; Fenclonine; Half-Life; Hydroxylation; Male; Norepinephrine; Organ Size; Phenylalanine; Rats; Rats, Inbred Strains; Self Stimulation; Serotonin; Tyramine; Tyrosine | 1972 |
The separation of three allosterically inhibitable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases from extracts of Neurospora crassa and the purification of the tyrosine inhibitable isoenzyme.
Topics: Aldehyde-Lyases; Allosteric Regulation; Ammonium Sulfate; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Drug Stability; Electrophoresis, Disc; Heptoses; Isoenzymes; Molecular Weight; Neurospora; Neurospora crassa; Phenylalanine; Phosphoenolpyruvate; Protamines; Sulfuric Acids; Tetroses; Time Factors; Tyrosine | 1972 |
On the mechanism of fever caused by the mucopeptide of group A streptococcus.
Topics: Animals; Bacterial Proteins; Brain; Disease Models, Animal; Fenclonine; Fever; Injections, Intravenous; Injections, Spinal; Mucoproteins; Norepinephrine; Phenylalanine; Premedication; Rabbits; Reserpine; Serotonin; Streptococcus; Streptococcus pyogenes; Tyrosine | 1972 |
Molecular basis of inhibition of monooxygenases by p-halophenylalanines.
Topics: Animals; Brain; Carbon Isotopes; Cycloheximide; Fenclonine; Liver; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Rats; Tryptophan; Tyrosine | 1972 |
Hyperaminoacidemia effects on intestinal transport of related amino acids.
Topics: Animals; Biological Transport; Diet; Female; Fenclonine; Glucose; Intestinal Absorption; Intestinal Mucosa; Kidney; Liver; Metabolic Clearance Rate; Mixed Function Oxygenases; Phenylalanine; Rats; Sodium; Stimulation, Chemical; Tryptophan; Tyrosine | 1972 |
Purification and stability of the multienzyme complex encoded in the arom gene cluster of Neurospora crassa.
Topics: Alcohol Oxidoreductases; Amino Acids; Aminobenzoates; Cyclohexanecarboxylic Acids; Drug Stability; Genes; Genetic Code; Hydro-Lyases; Hydrogen-Ion Concentration; Ligases; Macromolecular Substances; Methods; Molecular Weight; Multienzyme Complexes; Neurospora; Neurospora crassa; Peptides; Phenylalanine; Phosphoenolpyruvate; Phosphotransferases; Shikimic Acid; Tryptophan; Tyrosine | 1972 |
The effect of L-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Benzyl Compounds; Brain; Carboxy-Lyases; Dimethylamines; Dose-Response Relationship, Drug; Feedback; Female; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Mice; Nialamide; Phenylalanine; Reserpine; Sensory Receptor Cells; Serine; Serotonin; Tryptamines; Tryptophan; Tryptophan Hydroxylase; Tyrosine | 1972 |
Liver phenylalanine hydroxylase activity in relation to blood concentrations of tyrosine and phenylalanine in the rat.
Topics: Animals; Animals, Newborn; Fenclonine; Hydrocortisone; Liver; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Thyroxine; Tyrosine | 1972 |
Further characteristics of the association of thyroxine with adenohypophysial proteins in vitro.
Topics: Animals; Blood Proteins; Chemical Precipitation; Estrogens; Male; Phenylalanine; Pituitary Gland; Protein Binding; Rats; Thyroxine-Binding Proteins; Tyrosine | 1972 |
Chorismate mutase isozyme patterns in three fungi.
Topics: Chromatography, Thin Layer; Cinnamates; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Isoenzymes; Isomerases; Methyl Ethers; Multienzyme Complexes; Neurospora; Neurospora crassa; Penicillium; Penicillium chrysogenum; Phenylalanine; Species Specificity; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Vinyl Compounds | 1973 |
Experimental maternal hyperphenylalaninemia: disaggregation of fetal brain ribosomes.
Topics: Animals; Brain; Brain Chemistry; Centrifugation, Density Gradient; Female; Fenclonine; Fetus; Humans; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Polyribosomes; Pregnancy; Rats; Tryptophan; Tyrosine | 1973 |
A new class of p-fluorophenylalanine-resistant mutants in Neurospora crassa.
Topics: Aldehyde-Lyases; Amino Acids; Carbon Isotopes; Cyclohexanes; Cycloheximide; Drug Resistance, Microbial; Feedback; Fluorine; Genetic Linkage; Heptoses; Hydro-Lyases; Mutation; Neurospora; Neurospora crassa; Phenylalanine; Pyruvates; Tyrosine | 1972 |
Cellular compartmentation of aromatic amino acids in Neurospora crassa. I. Occupation of a protein synthesis pool by phenylalanine in Tyr-1 mutants.
Topics: Carbon Radioisotopes; Culture Media; Dialysis; Drug Resistance, Microbial; Fluorine; Fungal Proteins; Genetics, Microbial; Hydrogen-Ion Concentration; Kinetics; Mutation; Neurospora; Neurospora crassa; Phenylalanine; Solubility; Tyrosine; Water | 1973 |
Cellular compartmentation of aromatic amino acids in Neurospora crassa. II. Synthesis and misplaced accumulation of phenylalanine in phen-2 auxotrophs.
Topics: Aminoacylation; Biological Transport; Carbon Radioisotopes; Chromatography, Paper; Cyclohexanes; Cycloheximide; Dialysis; Feedback; Fungal Proteins; Genetics, Microbial; Hydro-Lyases; Mutation; Neurospora; Neurospora crassa; Phenylalanine; Pyruvates; Shikimic Acid; Time Factors; Tyrosine | 1973 |
Letter: Experimental production of steady-state elevation of a metabolizable amino acid in plasma.
Topics: Animals; Brain; Cats; Female; Fenclonine; Fluorometry; Injections, Intravenous; Kinetics; Male; Mathematics; Methods; Phenylalanine; Tyrosine | 1973 |
Brain catechol synthesis: control by train tyrosine concentration.
Topics: Alanine; Animals; Benserazide; Brain Chemistry; Dihydroxyphenylalanine; Fenclonine; Histidine; Leucine; Lysine; Male; Phenylalanine; Rats; Tryptophan; Tyrosine | 1974 |
Reduced activity in rats with induced phenylketonuria.
Topics: Animals; Body Weight; Diet; Eating; Exploratory Behavior; Fenclonine; Humans; Male; Motor Activity; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1972 |
Behavior and brain growth in rats treated with p-chlorophenylalanine in the first weeks of life.
Topics: Acoustic Stimulation; Animals; Animals, Newborn; Arousal; Auditory Perception; Avoidance Learning; Behavior, Animal; Body Weight; Brain; Brain Chemistry; Exploratory Behavior; Fenclonine; Habituation, Psychophysiologic; Motor Activity; Organ Size; Phenylalanine; Rats; Serotonin; Time Factors; Tyrosine | 1972 |
Glycolysis in the brain and liver of rats with experimentally induced phenylketonuria.
Topics: Animals; Autoanalysis; Brain; Chromatography, Ion Exchange; Esculin; Female; Fenclonine; Glycolysis; Humans; Kinetics; Liver; Phenylalanine; Phenylketonurias; Pyruvate Kinase; Rats; Structure-Activity Relationship; Time Factors; Tyrosine | 1974 |
[Role of some metabolic changes in the development of complications of pregnancy and labor in women with rheumatic heart disease].
Topics: Amino Acids; Calcium; Computers; Cysteine; Cystine; Female; Glutamine; Humans; Isoleucine; Leucine; Magnesium; Methionine; Niacinamide; Obstetric Labor Complications; Phenylalanine; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Rheumatic Heart Disease; Sodium; Tryptophan; Tyrosine; Valine; Vitamin E | 1974 |
Inhibition of phenylalanine hydroxylase by p-chlorophenylalanine; dependence on cofactor structure.
Topics: Binding Sites; Catalase; Fenclonine; Hydrogen-Ion Concentration; Kinetics; Liver; Phenylalanine; Phenylalanine Hydroxylase; Propylene Glycols; Protein Binding; Pteridines; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Temperature; Tyrosine | 1974 |
[Effect of catecholamines and their analogs on the electric activity of a giant neuron identified in the subesophageal ganglia of the giant african snail (Achatina fulica Ferussac)].
Topics: Action Potentials; Animals; Catecholamines; Dopamine; Epinephrine; Homovanillic Acid; Levodopa; Mandelic Acids; Methoxyhydroxyphenylglycol; Neural Conduction; Neurons; Norepinephrine; Normetanephrine; Octopamine; Phenylalanine; Snails; Structure-Activity Relationship; Synephrine; Tyramine; Tyrosine | 1974 |
[Application of electron spin resonance in radiation biology].
Topics: Alanine; Blood Proteins; Caseins; Electron Spin Resonance Spectroscopy; Globins; Glycine; Phenylalanine; Radiation Effects; Tobacco Mosaic Virus; Tryptophan; Tyrosine; Valine | 1965 |
[Further experimental studies on the catecholamine metabolism in extrapyramidal diseases (Parkinson and chorea syndromes)].
Topics: Aged; Carboxy-Lyases; Catecholamines; Chorea; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Middle Aged; NAD; Oxidoreductases; Parkinson Disease; Phenylalanine; Tyrosine | 1967 |
[Biochemical anomalies in rheumatoid polyarthritis].
Topics: Arthritis, Rheumatoid; Humans; Hydroxyproline; Phenylalanine; Tryptophan; Tyrosine | 1967 |
Location and characteristics of the phenylalanine transport mechanism in normal and polyoma-transformed hamster cells.
Topics: Amino Acids; Animals; Biological Transport; Cell Membrane; Chloromercuribenzoates; Cricetinae; Culture Techniques; Cytopathogenic Effect, Viral; Histidine; Leucine; Methionine; Neoplasms, Experimental; Phenylalanine; Polyomavirus; Sulfhydryl Compounds; Tryptophan; Tyrosine; Valine | 1967 |
Virus-directed protein synthesis in different animal and human cells.
Topics: Amnion; Animals; Carbon Isotopes; Culture Techniques; Cytopathogenic Effect, Viral; Electrophoresis, Disc; Encephalomyocarditis virus; Fibroblasts; HeLa Cells; Humans; Mice; Phenylalanine; Picornaviridae; Poliovirus; RNA Viruses; RNA, Viral; Tritium; Tyrosine; Valine; Viral Proteins | 1968 |
Primary structure of insoluble tendon collagen. II. N- and C-terminal positional analysis of collagenolytic breakdown products of trypsin-pretreated collagen.
Topics: Achilles Tendon; Alanine; Amino Acids; Animals; Arginine; Cattle; Collagen; Glycine; Hydroxyproline; Isoleucine; Leucine; Methionine; Methods; Microbial Collagenase; Phenylalanine; Proline; Threonine; Trypsin; Tyrosine | 1968 |
Feedback inhibition of glutamine synthetase of Neurospora crassa by nicotinamide-adenine dinucleotide.
Topics: Adenosine Triphosphate; Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Feedback; Glutamates; Glutamine; Guanine Nucleotides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Ligases; NAD; Neurospora; ortho-Aminobenzoates; Phenylalanine; Quaternary Ammonium Compounds; Tryptophan; Tyrosine | 1968 |
The divergence in reactivity of aminoacyl transfer ribonucleic acid synthetases of Escherichia coli with hydroxylamine.
Topics: Alanine; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Cysteine; Escherichia coli; Glutamates; Glycine; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lysine; Methionine; Periodic Acid; Phenylalanine; RNA, Bacterial; RNA, Transfer; Threonine; Tryptophan; Tyrosine | 1968 |
Failure to induce scurvy by ascorbic acid depletion in a patient with Hurler's syndrome.
Topics: Adrenocorticotropic Hormone; Amino Acids; Ascorbic Acid; Biopsy; Bone Development; Dentition; Diet Therapy; Female; Glycosaminoglycans; Hernia, Umbilical; Humans; Hydroxyproline; Infant; Mucopolysaccharidosis I; Phenylalanine; Scurvy; Skin; Tyrosine; Wound Healing | 1968 |
Tumor response to phenylalanine-tyrosine-limited diets.
Topics: Adenocarcinoma; Amino Acids; Animals; Carcinoma, Hepatocellular; Cystadenoma; Deficiency Diseases; Diet Therapy; Female; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Middle Aged; Neoplasms, Experimental; Ovarian Neoplasms; Phenylalanine; Sarcoma, Experimental; Tyrosine | 1969 |
Nature and mechanisms of oxygenases.
Topics: Amino Acids; Bacteria; Biotransformation; Catalysis; Catechol Oxidase; Chemical Phenomena; Chemistry; Cholesterol; Collagen; Dihydroxyphenylalanine; Flavin-Adenine Dinucleotide; Hydroxyproline; Lysine; NAD; Oxygen; Oxygenases; Phenylalanine; Plants; Prostaglandins; Squalene; Tryptophan Oxygenase; Tyrosine | 1969 |
Metabolic interlock. Regulatory interactions exerted between biochemical pathways.
Topics: Alanine; Bacillus subtilis; Cyclohexanecarboxylic Acids; Cyclohexanes; Diphosphates; Feedback; Histidine; Hydro-Lyases; Kinetics; Leucine; Metabolism; Methionine; Phenylalanine; Pyruvates; Thiophenes; Tryptophan; Tyrosine | 1969 |
A clinical syndrome and EEG-sleep changes associated with amino acid deprivation.
Topics: Aged; Deficiency Diseases; Diet; Electroencephalography; Female; Humans; Male; Memory; Memory Disorders; Memory, Short-Term; Middle Aged; Norepinephrine; Phenylalanine; Sleep, REM; Tyrosine | 1969 |
Inhibition of sterol synthesis in vitro by metabolites of phenylalanine.
Topics: Animals; Brain; Carbon Isotopes; Chemical Precipitation; Chromatography, Paper; Digitalis Glycosides; Diphosphates; Lactates; Liver; Mevalonic Acid; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rats; Sterols; Tyrosine | 1969 |
Electron paramagnetic resonance study of x-ray and gamma-ray irradiated peptides in the solid state.
Topics: Alanine; Amino Acid Sequence; Cobalt Isotopes; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Peptides; Phenylalanine; Radiation Effects; Temperature; Tryptophan; Tyrosine | 1969 |
[Phenylketonuria. 3. Evaluation of early treatment].
Topics: Blood Proteins; Child, Preschool; Diet Therapy; Female; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Phosphoric Monoester Hydrolases; Tryptophan; Tyrosine | 1969 |
On the phosphorescence of collagen.
Topics: Animals; Cattle; Cold Temperature; Collagen; Electron Spin Resonance Spectroscopy; Luminescent Measurements; Phenylalanine; Time Factors; Tyrosine; Ultraviolet Rays | 1969 |
Electron paramagnetic resonance study of free radical products of the reaction of ninhydrin with amino acids, peptides and proteins.
Topics: Alanine; Amino Acids; Aspartic Acid; Chemical Phenomena; Chemistry, Physical; Dipeptides; Electron Spin Resonance Spectroscopy; Ethanol; Free Radicals; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Lysine; Peptides; Phenylalanine; Proline; Proteins; Serine; Solutions; Tryptophan; Tyrosine; Valine | 1970 |
Activity of the phenylalanine hydroxylating system in liver of newborn, suckling and adult rats.
Topics: Aging; Aldehydes; Animals; Animals, Newborn; Body Weight; Carbon Isotopes; Female; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; Organ Size; Phenylalanine; Proteins; Rats; Tyrosine | 1969 |
Content, synthesis and collectability of amino acids in various structures of the brains of rhesus monkeys.
Topics: Alanine; Amino Acids; Aminobutyrates; Amygdala; Animals; Aspartic Acid; Behavior, Animal; Brain; Brain Chemistry; Carbon Isotopes; Caudate Nucleus; Central Nervous System; Cerebral Cortex; Glutamates; Glycine; Haplorhini; Hypothalamus; Isoleucine; Methods; Perfusion; Phenylalanine; Proline; Synaptic Transmission; Technology, Radiologic; Tyrosine; Valine | 1970 |
4-Thiouridine-specific spin-labeling of E. coli transfer RNA.
Topics: Chromatography, Ion Exchange; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Methionine; Nucleosides; Phenylalanine; Pyrrolidines; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Tyrosine; Ultraviolet Rays; Uracil Nucleotides; Valine | 1970 |
Stimulation by N6,O2'-dibutyryl adenosine 3',5'-cyclic-phosphate of amino acid transport, protein synthesis, and chondroitin sulfate synthesis in embryonic bone in vitro contrasted with the effects of thyroid hormones.
Topics: Adenine Nucleotides; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Bone and Bones; Butyrates; Chick Embryo; Chondroitin; Cyclic AMP; Leucine; Phenylalanine; Potassium; Protein Biosynthesis; Stimulation, Chemical; Sulfates; Sulfur Isotopes; Sulfuric Acids; Theophylline; Thyroid Hormones; Tritium; Tyrosine | 1970 |
Synthesis and cleavage of enterovirus polypeptides in mammalian cells.
Topics: Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Electrophoresis; Encephalomyocarditis virus; Enterovirus; HeLa Cells; Molecular Weight; Peptide Biosynthesis; Peptide Hydrolases; Phenylalanine; Poliovirus; Protein Biosynthesis; Tritium; Tyrosine; Valine; Viral Proteins | 1970 |
[Dietetics in hereditary enzyme deficiencies].
Topics: Amino Acid Metabolism, Inborn Errors; Carbohydrate Metabolism, Inborn Errors; Diarrhea, Infantile; Diet Therapy; Galactosemias; Homocystinuria; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1970 |
Triplet-state electron spin resonance of the aromatic amino acids and proteins.
Topics: Amino Acids; Electron Spin Resonance Spectroscopy; Phenylalanine; Proteins; Tryptophan; Tyrosine | 1970 |
[Study of free-radical products in the reaction of ninhydrin with amino acids].
Topics: Amino Acids; Electron Spin Resonance Spectroscopy; Free Radicals; Indicators and Reagents; Kinetics; Phenylalanine; Tryptophan; Tyrosine | 1967 |
Isolation of amino acid acceptor RNA from purified avian myeloblastosis virus.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Avian Leukosis Virus; Centrifugation, Density Gradient; Chick Embryo; Glycine; In Vitro Techniques; Isoleucine; Ligases; Methionine; Phenylalanine; Proline; Ribonucleases; RNA, Transfer; RNA, Viral; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
The enzymology of prephenate dehydrogenase in Bacillus subtilis.
Topics: Bacillus subtilis; Chemical Phenomena; Chemistry; Cyclohexanes; Enzyme Repression; Fluorometry; Hot Temperature; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Mutation; NAD; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Protein Binding; Pyruvates; Stereoisomerism; Tryptophan; Tyrosine | 1970 |
[Metabolic products of microorganisms. 87. L-2,5-Dihydrophenylalanine].
Topics: Absorption; Acetates; Anti-Bacterial Agents; Carbon; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Culture Media; Drug Antagonism; Esters; Filtration; Gels; Indicators and Reagents; Infrared Rays; Phenylalanine; Silicon Dioxide; Spectrum Analysis; Stereoisomerism; Streptomyces; Tyrosine | 1971 |
Maintenance and exchange of the aromatic amino acid pool in Escherichia coli.
Topics: Bacterial Proteins; Biological Transport; Biological Transport, Active; Culture Media; Escherichia coli; Gels; Models, Biological; Mutation; Phenylalanine; Silicon Dioxide; Solvents; Transduction, Genetic; Trichloroacetic Acid; Tritium; Tryptophan; Tyrosine | 1971 |
Formation of free radicals in aliphatic and aromatic amino acids by trapped electrons: an E.S.R. study.
Topics: Alanine; Amino Acids; Electron Spin Resonance Spectroscopy; Free Radicals; Glycine; Phenylalanine; Photochemistry; Radiochemistry; Spectrum Analysis; Tryptophan; Tyrosine | 1971 |
Myeloperoxidase of the leukocyte of normal blood. II. The oxidation-reduction reaction mechanism of the myeloperoxidase system.
Topics: Adrenochrome; Animals; Blood Platelets; Cytochromes; Dihydroxyphenylalanine; Dopamine; Epinephrine; Erythrocytes; Free Radicals; Hydrogen Peroxide; Iron; Leukocytes; Models, Chemical; NAD; Norepinephrine; Oxidation-Reduction; Oxidoreductases; Oxygen; Peroxidases; Phenols; Phenylalanine; Spectrophotometry; Swine; Time Factors; Tyrosine; Ultraviolet Rays | 1970 |
Alterations in specific transfer ribonucleic acids in a spectrum of hepatomas.
Topics: Animals; Asparagine; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Chromatography, Gel; Chromatography, Ion Exchange; Diploidy; Escherichia coli; Genetic Code; Hindlimb; Histidine; Ligases; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Phenylalanine; Polynucleotides; Polyploidy; Rats; Ribosomes; RNA, Transfer; Tritium; Tyrosine; Ultracentrifugation | 1971 |
Replacement of Mg 2+ by monovalent cations in aminoacyl transfer RNA formation.
Topics: Acetates; Adenosine Triphosphate; Ammonium Chloride; Aspartic Acid; Chlorides; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Paper; Dialysis; Diphosphates; Edetic Acid; Enzyme Activation; Escherichia coli; Histidine; Hydroxamic Acids; Hydroxyapatites; Hydroxylamines; Isoleucine; Kinetics; Leucine; Ligases; Lithium; Lysine; Magnesium; Methionine; Phenylalanine; Phosphorus Isotopes; Potassium Chloride; RNA, Transfer; Sodium Chloride; Tryptophan; Tyrosine; Valine | 1971 |
Structural determinants of catecholamine action on in vitro insulin release.
Topics: Animals; Butyrates; Catecholamines; Cricetinae; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Methyldopa; Norepinephrine; Pancreas; Phenethylamines; Phentolamine; Phenylacetates; Phenylalanine; Phenylephrine; Structure-Activity Relationship; Tyramine; Tyrosine | 1971 |
Alterations in the transfer RNA population of hepatoma 9618A as compared with normal rat liver.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; Histidine; Leucine; Liver; Liver Neoplasms; Lysine; Male; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer; Serine; Tritium; Tyrosine | 1971 |
Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Analysis of the phenylalanine binding site.
Topics: Adenosine Triphosphate; Amides; Amino Acyl-tRNA Synthetases; Amino Alcohols; Amphetamine; Anilides; Aniline Compounds; Binding Sites; Chemical Phenomena; Chemistry; Chlorine; Diphosphates; Escherichia coli; Fluorine; Models, Chemical; Nitro Compounds; Phenols; Phenylalanine; Phosphorus Isotopes; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Tyrosine | 1971 |
The inactivation of phenylalanine hydroxylase by 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine and the aerobic oxidation of the latter. The effects of catalase, dithiothreitol and reduced nicotinamide-adenine dinucleotide.
Topics: Air; Animals; Catalase; Coenzymes; Dithiothreitol; Hydrogen Peroxide; Liver; Liver Extracts; Mice; Mixed Function Oxygenases; NAD; Oxidation-Reduction; Peroxides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Rats; Tyrosine | 1971 |
Chemical studies of structural features in staphylococcal nuclease-T'.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; Chemical Phenomena; Chemistry; Crystallography; Deoxyribonucleases; Drug Stability; Methane; Models, Structural; Nitro Compounds; Peptides; Phenylalanine; Phosphoric Monoester Hydrolases; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Staphylococcus; Time Factors; Trypsin; Tyrosine; Ultraviolet Rays | 1972 |
Inactivation of T u factor-guanosine triphosphate recognition and ribosome-binding ability by terminal oxidation-reduction of yeast phenylalanine transfer ribonucleic acid.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Binding Sites; Borohydrides; Carbon Isotopes; Escherichia coli; Guanosine Triphosphate; Hydrogen-Ion Concentration; Kinetics; Magnesium; Osmolar Concentration; Oxidation-Reduction; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Periodic Acid; Phenylalanine; Ribonucleases; Ribosomes; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Transfer RNA Aminoacylation; Tritium; Tyrosine | 1972 |
ESR studies of the low temperature irradiation of keratin and its component amino acids.
Topics: Amino Acids; Animals; Chemical Phenomena; Chemistry; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Freezing; Indoles; Keratins; Muramidase; Phenylalanine; Radiation Effects; Tryptophan; Tyrosine; Tyrothricin; Ultraviolet Rays; Wool | 1972 |
Mechanisms by which human blood platelets accumulate glycine, gaba and amino acid precursors of putative neurotransmitters.
Topics: Amino Acids; Aminobutyrates; Blood Platelets; Carbon Isotopes; Central Nervous System; Dihydroxyphenylalanine; Female; Glycine; Humans; In Vitro Techniques; Male; Phenylalanine; Protein Binding; Receptors, Drug; Synaptic Transmission; Tryptophan; Tyrosine | 1972 |
Reaction of the main proteolytic fraction of Schistosoma mansoni cercarial enzymes with synthetic substrates and inhibitors of proteolytic enzymes.
Topics: Acetates; Animals; Bradykinin; Chymotrypsin; Esters; Guinea Pigs; Hydrolysis; Ileum; Isoflurophate; Microbial Collagenase; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Schistosoma mansoni; Trypsin; Tyrosine | 1972 |
Partial degradation of transfer RNAs and transfer RNA fragments by spleen phosphodiesterase as studied by disc electrophoretic methods.
Topics: Animals; Base Sequence; Chemical Phenomena; Chemistry; Densitometry; Electrophoresis, Disc; Escherichia coli; Kinetics; Methods; Oligonucleotides; Phenylalanine; Phosphoric Acids; Phosphoric Diester Hydrolases; RNA, Bacterial; RNA, Transfer; Serine; Spleen; Swine; Tyrosine | 1972 |
Partial degradation of transfer RNAs by sheep kidney nuclease.
Topics: Adenine Nucleotides; Alkaline Phosphatase; Animals; Coliphages; Cytosine Nucleotides; Electrophoresis, Disc; Escherichia coli; Kidney; Kinetics; Magnesium; Oligonucleotides; Phenylalanine; Phosphoric Diester Hydrolases; Polynucleotides; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Serine; Sheep; Snakes; Tyrosine; Uracil Nucleotides; Valine; Venoms | 1972 |
Angiotensin-receptor interaction: influence of pH on angiotensin inhibition by Phe 4 -Tyr 8 -angiotensin II in rat uterine smooth muscle.
Topics: Angiotensin II; Animals; Binding Sites; Buffers; Female; Hydrogen-Ion Concentration; Muscle Contraction; Muscle, Smooth; Phenylalanine; Rats; Receptors, Drug; Tyrosine; Uterus | 1972 |
Chromatographic studies of tyrosyl and phenylalanyl transfer RNA's of liver and tumor cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cells, Cultured; Chromatography; Cricetinae; Escherichia coli; In Vitro Techniques; Liver; Liver Neoplasms; Mice; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; RNA, Transfer; Simian virus 40; Tumor Virus Infections; Tyrosine | 1973 |
The use of isocyanides for the immobilization of biological molecules.
Topics: Acrylamides; Adenosine Monophosphate; Biotin; Chromatography, Gel; Chymotrypsin; Cyanides; Esters; Humans; Hydrogen-Ion Concentration; Leucine; Methods; Molecular Weight; NAD; Penicillanic Acid; Penicillin G; Phenylalanine; Protein Binding; RNA; Serum Albumin; Temperature; Tyrosine | 1973 |
The degradation of L-histidine in the rat. The formation of imidazolylpyruvate, imidazolyl-lactate and imidazolylpropionate.
Topics: Alcohol Oxidoreductases; Animals; Chromatography, DEAE-Cellulose; Histidine; Imidazoles; Intestines; Ketoglutaric Acids; L-Lactate Dehydrogenase; Lactates; Mitochondria, Liver; Molecular Weight; NAD; Phenylalanine; Propionates; Pyruvates; Rats; Transaminases; Tyrosine | 1973 |
Streptomycin resistance and ribosomal proteins: amino acid substitutions in the str protein of one streptomycin-resistant mutant of Escherichia coli K12 after mutagenesis with ethyl methanesulfonate.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Paper; Chromatography, Thin Layer; Drug Resistance, Microbial; Electrophoresis, Paper; Escherichia coli; Mesylates; Molecular Weight; Mutation; Peptide Fragments; Phenylalanine; Ribosomes; Spectrophotometry; Streptomycin; Trypsin; Tyrosine; Valine | 1974 |
Radical yield in X-irradiated biological molecules. II. Naturally-occurring amino-acids.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cysteine; Cystine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamates; Histamine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Carbon Radioisotopes; Cerebral Cortex; Glutamates; Glycine; Histidine; In Vitro Techniques; Lysine; Male; Membrane Potentials; Phenylalanine; Potassium; Proline; Rats; Sodium; Spinal Cord; Synaptic Transmission; Synaptosomes; Tritium; Tyrosine | 1974 |
Effect on growth and structure of transplantable malignant melanomas of the Syrian golden hamster (Mesocricetus auratus) by depletion of phenylalanine and tyrosine in the diet and by inhibition of tyrosinase. Brief report.
Topics: Animals; Catechol Oxidase; Copper; Cricetinae; Cytoplasmic Granules; Diet; Genitalia; Hair; Melanocytes; Melanoma; Microscopy, Electron; Neoplasm Transplantation; Penicillamine; Phenylalanine; Pigmentation; Tyrosine | 1974 |
Fructose-1,6-diphosphatase deficiency: another enzyme defect which can present itself with the clinical features of "tyrosinosis".
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Carbohydrate Metabolism, Inborn Errors; Chromatography, Gas; Cystathionine; Dietary Carbohydrates; Female; Fructose-1,6-Diphosphatase Deficiency; Fructose-Bisphosphatase; Humans; Infant; Lactates; Methionine; Phenylalanine; Sucrose; Tyrosine | 1974 |
Alkaline isomerization of ferricytochrome C from Euglena gracilis.
Topics: Animals; Binding Sites; Chromatography, DEAE-Cellulose; Cytochrome c Group; Euglena gracilis; Horses; Hydrogen-Ion Concentration; Isomerism; Ligands; Mathematics; Myocardium; Phenylalanine; Protein Binding; Protein Conformation; Species Specificity; Spectrophotometry; Tyrosine | 1974 |
Inhibitory effect of complex formation with oligodeoxyribonucleotide ethyl phosphotriesters on transfer ribonucleic acid aminoacylation.
Topics: Amino Acyl-tRNA Synthetases; Anticodon; Base Sequence; Binding Sites; Deoxyribonucleotides; Diphosphates; Escherichia coli; Kinetics; Leucine; Lysine; Oligonucleotides; Phenylalanine; Phosphorus Radioisotopes; Proline; Protein Binding; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Time Factors; Tritium; Tyrosine | 1974 |
Amino acid esters of 2'-O-methyladenosing -peptide acceptors in the ribosome. The role of 2'-hydroxyl.
Topics: Adenosine; Carbon Radioisotopes; Cell-Free System; Chromatography; Chromatography, Paper; Dicyclohexylcarbodiimide; Escherichia coli; Kinetics; Phenylalanine; Puromycin; Ribosomes; RNA, Bacterial; RNA, Transfer; Silicon Dioxide; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Time Factors; Tyrosine | 1974 |
Effect of phenylalanine and p-chlorophenylalanine administration on the development of rat brain 2',3'-cyclic nucleotide 3'-phosphohydrolase.
Topics: Age Factors; Animals; Body Weight; Brain; Cerebellum; Electron Transport Complex IV; Female; Fenclonine; Hexokinase; Nucleotides, Cyclic; Organ Size; Phenylalanine; Phosphoric Monoester Hydrolases; Pregnancy; Rats; Tyrosine | 1974 |
Effects of altered thyroid function in rats upon the formation and distribution of tyrosine.
Topics: Animals; Blood; Chromatography, Paper; Hyperthyroidism; Liver; Mixed Function Oxygenases; Phenylalanine; Rats; Thyroxine; Tyrosine; Tyrosine Transaminase | 1965 |
Some biochemical changes in hamsters fed excess phenylalanine diets.
Topics: Animals; Cricetinae; Diet; Liver; Mixed Function Oxygenases; Phenylalanine; Transaminases; Tyrosine; Tyrosine Transaminase | 1966 |
The interaction of pyridoxal phosphate with tyrosine analogs.
Topics: Animals; Dihydroxyphenylalanine; Dopamine; Enzymes; Epinephrine; In Vitro Techniques; Liver; Male; Methyldopa; Methyltyrosines; Normetanephrine; Octopamine; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase; Ultraviolet Rays | 1966 |
Isotopic method for tyrosine transaminase activity.
Topics: Amino Acids; Animals; Buffers; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Indicators and Reagents; Keto Acids; Ketoglutaric Acids; Liver; Phenylalanine; Pyruvates; Rats; Tryptophan; Tyrosine; Tyrosine Transaminase | 1967 |
Aromatic amino acid biosynthesis: gene-enzyme relationships in Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Chromosome Mapping; DNA, Bacterial; Genes; Genes, Regulator; Genetic Code; Genetics, Microbial; Genotype; Ligases; Molecular Biology; Mutation; Oxidoreductases; Phenotype; Phenylalanine; Phosphotransferases; Shikimic Acid; Transaminases; Transformation, Genetic; Tryptophan; Tyrosine; Tyrosine Transaminase | 1967 |
Starvation metabolism and plasma corticosterone with reference to the actions of metopirone and propylthiouracil.
Topics: Adipose Tissue; Alanine Transaminase; Animals; Corticosterone; Liver; Liver Glycogen; Male; Metyrapone; Organ Size; Phenylalanine; Propylthiouracil; Proteins; Rats; Starvation; Tyrosine; Tyrosine Transaminase; Water | 1968 |
[On the accumulation of chorismic acid in mutants and wild strains of Escherichia coli and Saccharomyces cerevisiae].
Topics: Chromatography, Paper; Cyclohexanecarboxylic Acids; Escherichia coli; Genetics, Microbial; Molecular Biology; Mutation; Phenylalanine; Saccharomyces; Tyrosine | 1967 |
Tyrosine synthesis in a Pseudomonas species.
Topics: Enzyme Induction; Glutamates; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Tyrosine; Tyrosine Transaminase | 1968 |
[On the biogenesis of 5-hydroxy-1,4-napthoquinone (juglone) in Juglans regia L].
Topics: Aldehydes; Benzoates; Carbon Isotopes; Cyclohexanecarboxylic Acids; Enterobacter; Escherichia coli; Malonates; Naphthoquinones; Phenylalanine; Phthalic Acids; Plant Proteins; Plants; Shikimic Acid; Tyrosine | 1968 |
[On the radiation inactivation of ribonuclease. 3. Changes in amino acids following irradiation in vacuo].
Topics: Amino Acids; Chromatography, Gel; Cystine; Histidine; Lysine; Methionine; Oxygen; Phenylalanine; Radiation Effects; Radiochemistry; Ribonucleases; Tyrosine; Ultracentrifugation | 1968 |
On the synthesis of tyrosine transaminase in vitro.
Topics: Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Hydrocortisone; Liver; Male; Microsomes; Phenylalanine; Puromycin; Pyridoxal Phosphate; Rats; Ribonucleases; Tritium; Tyrosine; Tyrosine Transaminase | 1969 |
Aromatic amino acid metabolism in the wabbler-lethal mouse.
Topics: Aging; Animals; Liver; Mice; Mixed Function Oxygenases; Nervous System Diseases; Phenylalanine; Rodent Diseases; Transaminases; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase | 1969 |
Subcellular distribution of tyrosine aminotransferase in rat brain.
Topics: Animals; Brain; Cell Nucleus; Centrifugation, Density Gradient; Dihydroxyphenylalanine; Ketoglutaric Acids; Kinetics; Male; Microscopy, Electron; Microsomes; Mitochondria; Monoamine Oxidase; Monoiodotyrosine; Nerve Endings; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Tryptophan; Tyrosine; Tyrosine Transaminase | 1969 |
Biochemical observations on so-called hereditary tyrosinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Biopsy; Diet Therapy; Female; Hepatomegaly; Humans; Hydro-Lyases; Infant; Infant, Newborn; Liver; Male; Methionine; Mixed Function Oxygenases; Phenotype; Phenylalanine; Phosphates; Splenomegaly; Transferases; Tyrosine; Tyrosine Transaminase | 1970 |
The role of pteridine cofactors in mixed function oxidases.
Topics: Adrenal Glands; Animals; Cattle; Liver; Mixed Function Oxygenases; NADP; Phenylalanine; Pteridines; Rats; Tyrosine | 1968 |
Fluorometric assay of amino acids.
Topics: Amino Acid Oxidoreductases; Amino Acids; Arginine; Benzoates; D-Amino-Acid Oxidase; Fluorometry; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Leucine; Methionine; Methods; Phenylacetates; Phenylalanine; Proline; Stereoisomerism; Tryptophan; Tyrosine | 1968 |
Relationship of phenylalanine to seizure threshold during maturation.
Topics: Age Factors; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Injections, Intraperitoneal; Male; Phenylalanine; Rats; Seizures; Tyrosine | 1970 |
Studies of highly purified tyrosine aminotransferase in rat brain.
Topics: Animals; Brain; Electrophoresis, Disc; Fumarates; Glutarates; Kinetics; Maleates; Mitochondria; Monoiodotyrosine; Norepinephrine; Phenylacetates; Phenylalanine; Radiometry; Rats; Spectrophotometry; Tyrosine; Tyrosine Transaminase | 1971 |
The formation of 3,4-dihydroxy-L-phenylalanine from L-meta-tyrosine by rat liver and beef adrenal medulla.
Topics: Adrenal Glands; Amino Acids; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Cattle; Chemical Precipitation; Chromatography, Ion Exchange; Cresols; Depression, Chemical; Dihydroxyphenylalanine; Ethanol; Female; Fluorescence; Hydroxylamines; Isomerism; Liver; Mixed Function Oxygenases; NADP; Phenylalanine; Pteridines; Quaternary Ammonium Compounds; Rats; Stimulation, Chemical; Sulfates; Tyrosine | 1971 |
Regulation of tyrosine biosynthesis in Escherichia coli K-12: isolation and characterization of operator mutants.
Topics: Aldehyde-Lyases; Alleles; Cell-Free System; Chromosome Mapping; Coliphages; Conjugation, Genetic; Culture Media; Diploidy; Drug Resistance, Microbial; Enzyme Repression; Escherichia coli; Genes; Genetics, Microbial; Mutation; Oxidoreductases; Phenylalanine; Phosphotransferases; Transduction, Genetic; Tryptophan; Tyrosine; Tyrosine Transaminase | 1971 |
The influence of tyrosine, phenylpyruvate and vitamin B 6 upon seizure thresholds.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Central Nervous System Stimulants; Ethers; Fluorine; Male; Myoclonus; Phenylalanine; Phenylpyruvic Acids; Pyridoxal Phosphate; Pyridoxine; Rats; Seizures; Time Factors; Tyrosine | 1971 |
Formation of meta-tyrosine form L-phenylalanine by beef adrenal medulla. A new biosynthetic route to catecholamines.
Topics: Adrenal Medulla; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbon Isotopes; Catecholamines; Cattle; Chromatography, Ion Exchange; Cresols; Dihydroxyphenylalanine; Female; Hydroxylamines; Iron; Kinetics; Methyltyrosines; Monoiodotyrosine; NAD; Phenols; Phenylalanine; Pteridines; Rats; Stereoisomerism; Tyrosine; Tyrosine 3-Monooxygenase | 1971 |
Studies of the activity of chymotrypsin.
Topics: Amides; Chemical Phenomena; Chemistry; Chymotrypsin; Circular Dichroism; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leucine; Phenylalanine; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tryptophan; Tyrosine | 1970 |
Repression of aromatic amino acid biosynthesis in Escherichia coli K-12.
Topics: Aldehyde-Lyases; Alleles; Cell-Free System; Chromosome Mapping; Culture Media; Cyclohexanecarboxylic Acids; Enzyme Repression; Escherichia coli; Genes, Regulator; Genetics, Microbial; Heptoses; Hydro-Lyases; Isoenzymes; Mutation; Oxidoreductases; Phenylalanine; Quinic Acid; Tetroses; Transaminases; Transduction, Genetic; Tryptophan; Tyrosine; Tyrosine Transaminase | 1971 |
Phenylalanine and tyrosine biosynthesis in Escherichia coli K-12: mutants derepressed for 3-deoxy-D-arabinoheptulosonic acid 7-phosphate synthetase (phe), 3-deoxy-D-arabinoheptulosonic acid 7-phosphate synthetase (tyr), chorismate mutase T-prephenate dehy
Topics: Aldehyde-Lyases; Alleles; Cell-Free System; Chromosome Mapping; Culture Media; Cyclohexanecarboxylic Acids; Drug Resistance, Microbial; Enzyme Repression; Escherichia coli; Genes; Genetics, Microbial; Heptoses; Hydro-Lyases; Isoenzymes; Mutation; Phenylalanine; Recombination, Genetic; Tetroses; Transduction, Genetic; Tyrosine; Tyrosine Transaminase | 1971 |
Mutant strains of Escherichia coli K12 that use D-amino acids.
Topics: Amino Acids; Arginine; Chromosome Mapping; Coliphages; D-Amino-Acid Oxidase; Escherichia coli; Genetic Linkage; Genotype; Histidine; Isoleucine; Isomerism; Leucine; Lysine; Mutation; Phenylalanine; Proline; Serine; Threonine; Transduction, Genetic; Tryptophan; Tyrosine; Valine | 1971 |
[Hydroxylation of phenylalanine by Hydrogenomonas eutropha H 16].
Topics: Cell-Free System; Chromatography, Gel; Enzyme Induction; Mixed Function Oxygenases; NAD; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pseudomonas; Tryptophan; Tyrosine | 1972 |
The biosynthesis of octopamine.
Topics: Animals; Brain; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Half-Life; In Vitro Techniques; Male; Methyltyrosines; Monoamine Oxidase Inhibitors; Monoiodotyrosine; Myocardium; Octopamine; Phenylalanine; Rats; Tyramine; Tyrosine; Tyrosine 3-Monooxygenase | 1972 |
The influence of the aromatic amino acid side-chains on the sign of the Soret Cotton effect in chironomus hemoglobin (CTT 3).
Topics: Circular Dichroism; Diptera; Hemoglobins; Optical Rotatory Dispersion; Phenylalanine; Tryptophan; Tyrosine | 1972 |
Nonidentity of the aspartate and the aromatic aminotransferase components of transaminase A in Escherichia coli.
Topics: Aspartate Aminotransferases; Aspartic Acid; Cell-Free System; Chromatography, Gel; Culture Media; Electrophoresis, Disc; Enzyme Repression; Escherichia coli; Genetics, Microbial; Hot Temperature; Molecular Weight; Mutation; Phenylalanine; Transaminases; Tryptophan; Tyrosine; Tyrosine Transaminase | 1972 |
Regulation of the tyrosine biosynthetic enzymes in Salmonella typhimurium: analysis of the involvement of tyrosyl-transfer ribonucleic acid and tyrosyl-transfer ribonucleic acid synthetase.
Topics: Aldehyde-Lyases; Amino Acids; Amino Acyl-tRNA Synthetases; Cell-Free System; Cyclohexanes; Enzyme Repression; Genes, Regulator; Hydro-Lyases; Leucine; Mutation; Nitro Compounds; Oxidoreductases; Phenylalanine; Pyruvates; RNA, Transfer; Salmonella typhimurium; Transduction, Genetic; Tritium; Tyrosine; Tyrosine Transaminase | 1972 |
Detection of hepatic phenylalanine 4-hydroxylase in classical phenylketonuria.
Topics: Carbon Isotopes; Enzyme Induction; Humans; Kinetics; Liver; Lysophosphatidylcholines; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pterins; Tyrosine; Tyrosine 3-Monooxygenase | 1973 |
The formation in vivo of 3,4-dihydroxyphenylalanine (DOPA) from 3-hydroxy-DL-phenylalanine (m-tyrosine).
Topics: Animals; Benzyl Compounds; Brain; Brain Chemistry; Carboxy-Lyases; Depression, Chemical; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Hydrazines; Kinetics; Liver; Male; Phenylalanine; Propionates; Stimulation, Chemical; Time Factors; Tyrosine | 1974 |
In vitro studies on the uptake and incorporation of natural amino acids in rabbit choroid plexus.
Topics: Absorption; Amino Acids; Animals; Biological Transport; Carbon Radioisotopes; Chloramphenicol; Choroid Plexus; Cycloheximide; Glutamates; Glycine; Histidine; Inulin; Isoleucine; Kinetics; Leucine; Osmotic Pressure; Phenylalanine; Proline; Puromycin; Rabbits; Tritium; Tyrosine | 1974 |
Relaxation spectra of proteinases. Isomerizations of carboxypeptidase A (Cox) and (Anson).
Topics: Animals; Benzene Derivatives; Binding Sites; Binding, Competitive; Carboxypeptidases; Catalysis; Cattle; Dipeptides; Endopeptidases; Feedback; Glycine; Hydrogen-Ion Concentration; Indicators and Reagents; Isomerism; Kinetics; Lactates; Mandelic Acids; Pancreas; Phenylalanine; Protease Inhibitors; Protons; Spectrophotometry; Temperature; Tyrosine | 1974 |
[Amino acid imbalance as a pathogenetic factor in mental retardation (author's transl)].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain Chemistry; Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intellectual Disability; Leucine; Methionine; Phenylalanine; Phenylketonurias; Rats; Tyrosine; Valine | 1974 |
[Clinical importance of analysis of phenylalanine and tyrosine and their metabolites in infectious hepatitis].
Topics: Hepatitis A; Humans; Phenylalanine; Phenylpyruvic Acids; Tyrosine | 1974 |
Intestinal transport of aromatic amino acids, glucose and electrolytes in a patient with phenylketonuria.
Topics: Adult; Biological Transport; Female; Glucose; Humans; Intestinal Mucosa; Male; Molecular Weight; Phenylalanine; Phenylketonurias; Polyethylene Glycols; Potassium; Sodium; Time Factors; Tryptophan; Tyrosine | 1974 |
Quantitative studies on the urinary excretion of unconjugated aromatic acids in phenylketonuria.
Topics: Adolescent; Adult; Carboxylic Acids; Child; Child, Preschool; Diet; Fasting; Female; Follow-Up Studies; Granulocytes; Humans; Infant; Infant, Newborn; Lactates; Male; Mandelic Acids; Phenols; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Probability; Time Factors; Tyrosine | 1974 |
Regulation of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthetase in Brevibacterium flavum.
Topics: Aldehyde-Lyases; Amino Acids; Aminobenzoates; Brevibacterium; Cobalt; Dithiothreitol; Heptoses; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Phenylalanine; Phosphoenolpyruvate; Sugar Phosphates; Tetroses; Tryptophan; Tyrosine | 1974 |
Thin-layer chromatographic screening of amino acids in plasma and urine of newborns.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Arginine; Blood Proteins; Chromatography, Thin Layer; Female; Glycine; Homocysteine; Humans; Indicators and Reagents; Infant, Newborn; Infant, Premature; Lysine; Methionine; Phenylalanine; Pregnancy; Proteinuria; Tyrosine; Ultrafiltration | 1974 |
Feto-maternal amino acid metabolism.
Topics: Amino Acids; Amniocentesis; Amniotic Fluid; Arginine; Autoanalysis; Carnosine; Ethanolamines; Female; Fetus; Gestational Age; Glycine; Humans; Hydroxyproline; Infant, Newborn; Lysine; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Serine; Tyrosine; Umbilical Cord | 1974 |
Reduced intake of phenylalanine and tyrosine as treatment of choroidal malignant melanoma.
Topics: Choroid Neoplasms; Dietary Proteins; Female; Humans; Melanins; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasms, Multiple Primary; Phenylalanine; Remission, Spontaneous; Tyrosine; Ultrasonics; Vision, Ocular; Visual Fields | 1974 |
The influence of phenylalanine- and tyrosine-low diet on the growth and structure of transplantable malignant melanomas of the Syrian golden hamster (Mesocricetus auratus).
Topics: Amino Acids; Animals; Cricetinae; Cytoplasm; Dietary Proteins; Genitalia; Hair; Macrophages; Melanins; Melanocytes; Melanoma; Microscopy, Electron; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Skin; Skin Neoplasms; Transplantation, Homologous; Tyrosine | 1974 |
Melanocytic neoplasms.
Topics: Dihydroxyphenylalanine; Epinephrine; Humans; Melanins; Melanocytes; Melanoma; Mustard Compounds; Neoplasm Metastasis; Neurons; Phenylalanine; Pigments, Biological; Skin Neoplasms; Tyrosine | 1974 |
Tryptophan metabolism in Ochromonas malhamensis.
Topics: Adenine; Culture Media; Eukaryota; Folic Acid; Indoles; Phenylalanine; Pyridoxal; Tryptophan; Tryptophan Synthase; Tyrosine; Vitamin B 12 | 1974 |
Electron radiation damage of thin films of glycine, diglycine, and aromatic amino acids.
Topics: Amino Acids; Dipeptides; Dose-Response Relationship, Radiation; Electrons; Glycine; Histidine; Microscopy, Electron, Scanning; Phenylalanine; Radiation Effects; Tryptophan; Tyrosine | 1974 |
[Amino acid levels in the blood serum of patients with chronic colitis].
Topics: Adult; Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Betaine; Chronic Disease; Citrulline; Colitis; Glutamates; Glutamine; Glycine; Histidine; Humans; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tryptophan; Tyrosine; Urea | 1974 |
Regulation of aromatic amino acid biosynthesis in higher plants. Properties of an aromatic amino acid-sensitive chorismate mutase (CM-1) from mung bean.
Topics: Antimetabolites; Cations, Divalent; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyclohexanecarboxylic Acids; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxyapatites; Isoenzymes; Isomerases; Isomerism; Kinetics; Molecular Weight; Phenylalanine; Plants; Structure-Activity Relationship; Sulfhydryl Reagents; Tryptophan; Tyrosine; Vinyl Compounds | 1974 |
Purification and some properties of bovine pineal tryptophan 5-monooxygenase.
Topics: Animals; Carbon Radioisotopes; Cattle; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Dithiothreitol; Iron; Kinetics; Liver; Mixed Function Oxygenases; Molecular Weight; Phenylalanine; Phenylalanine Hydroxylase; Pineal Gland; Pterins; Rats; Tryptophan; Tryptophan Hydroxylase; Tyrosine | 1974 |
Gas-liquid chromatography of phenylalanine metabolites in urine and sera of hyperphenylalaninemic and phenylketonuric patients.
Topics: Amino Acid Metabolism, Inborn Errors; Autoanalysis; Chromatography, Gas; Humans; Hydrogen-Ion Concentration; Lactates; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Time Factors; Tyrosine | 1974 |
Thermal difference spectra of aromatic amino acids in water.
Topics: Acetates; Ethanol; Mathematics; Molecular Conformation; Phenylalanine; Spectrophotometry, Ultraviolet; Temperature; Tryptophan; Tyrosine; Water | 1974 |
Phenylalanine metabolism in chronic renal failure.
Topics: Adult; Aged; Blood Urea Nitrogen; Creatinine; Fasting; Female; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine; Uremia | 1974 |
Free amino acid levels in the boll weevil (Coleoptera: Curculionidae): the effect of five different diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography, Gas; Coleoptera; Diet; Dietary Proteins; Glutamates; Glycine; Gossypium; Histidine; Isoleucine; Leucine; Male; Mass Spectrometry; Methionine; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine; Valine | 1974 |
[Free amino acids in the 24 h urine of healthy children (author's transl)].
Topics: Adolescent; Age Factors; Alanine; Amino Acids; Aminobutyrates; Carnosine; Child; Chromatography, Ion Exchange; Citrulline; Female; Glycine; Histidine; Humans; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Serine; Sex Factors; Threonine; Tyrosine; Valine | 1974 |
[Amino acid determinations in the serum of patients with multiple sclerosis (author's transl)].
Topics: Amino Acids; Chromatography; Hot Temperature; Humans; Multiple Sclerosis; Phenylalanine; Tyrosine | 1974 |
Control of brain serotonin by the diet.
Topics: Animals; Blood Glucose; Brain; Circadian Rhythm; Dietary Carbohydrates; Dietary Proteins; Fatty Acids, Nonesterified; Indoles; Insulin; Isoleucine; Leucine; Phenylalanine; Protein Binding; Rats; Serotonin; Time Factors; Tryptophan; Tyrosine; Valine | 1974 |
Renal handling of aromatic amino acids, sugar, and standard glomerular markers in winter flounder.
Topics: Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Creatinine; Fishes; Inulin; Kidney; Phenylalanine; Polyethylene Glycols; Probenecid; Protein Binding; Tritium; Tyrosine | 1974 |
Phenylalaninaemia. Differential diagnosis.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Diagnosis, Differential; Diet Therapy; Dietary Proteins; Electroencephalography; Humans; Infant, Newborn; Mass Screening; Methods; Phenylacetates; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1974 |
Constitutive aromatic L-amino acid decarboxylase from Micrococcus percitreus.
Topics: Carboxy-Lyases; Chromatography, Gel; Chromatography, Ion Exchange; Crystallization; Drug Stability; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Micrococcus; Molecular Weight; Phenylalanine; Protamines; Protein Binding; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tyrosine; Ultracentrifugation | 1974 |
Bone morphogenesis in implants of residues of radioisotope labelled bone matrix.
Topics: Animals; Autoradiography; Bone Matrix; Buffers; Collagen; Hydrogen-Ion Concentration; Osteogenesis; Peptide Hydrolases; Phenylalanine; Radioisotopes; Rats; Sodium Isotopes; Solutions; Sulfates; Transplantation, Homologous; Tritium; Trypsin; Tryptophan; Tyrosine | 1974 |
Genetic mapping and complementation of aromatic mutants in Streptomyces coelicolor A3(2).
Topics: Chromosome Mapping; Crosses, Genetic; Genes; Genetic Complementation Test; Genetic Linkage; Mutation; Phenylalanine; Quinic Acid; Recombination, Genetic; Shikimic Acid; Streptomyces; Tryptophan; Tyrosine; Vitamins | 1974 |
Free amino acids in the haemocytes and plasma of the larva of Calliphora vicina.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Blood Cells; Blood Coagulation; Diptera; Glutamates; Glutamine; Glycine; Hemolymph; Histidine; Isoleucine; Larva; Leucine; Lysine; Methionine; Phenylalanine; Plasma; Proline; Serine; Taurine; Threonine; Tyrosine; Valine | 1974 |
Inhibitory effect of some amino acid derivatives on cobalt-activated acylase.
Topics: Adult; Alanine; Amidohydrolases; Amino Acids; Cobalt; Colorimetry; Deamination; Dipeptides; Enzyme Activation; Female; Humans; Leucine; Liver; Nitrous Acid; Peptide Chain Elongation, Translational; Phenylalanine; Tyrosine | 1974 |
3-Deoxy-D-arabino-heptulosonate-7-phosphate synthetase of Mycobacterium phlei: partial purification anD feedback inhibition.
Topics: Aldehyde-Lyases; Cobalt; Feedback; Hydrogen-Ion Concentration; Kinetics; Mycobacterium; Phenylalanine; Phosphoenolpyruvate; Sugar Phosphates; Tetroses; Tryptophan; Tyrosine; Zinc | 1974 |
Separability of enzymes of the common aromatic biosynthetic pathway in Mycobacterium phlei.
Topics: Alcohol Oxidoreductases; Aldehyde-Lyases; Chromatography, DEAE-Cellulose; Cyclohexanecarboxylic Acids; Heptoses; Hydro-Lyases; Isoenzymes; Isomerases; Ligases; Mycobacterium; Phenylalanine; Phosphoenolpyruvate; Shikimic Acid; Spectrophotometry; Tetroses; Tryptophan; Tyrosine | 1974 |
[Tyrosinosis].
Topics: Amino Acid Metabolism, Inborn Errors; Child; Chromatography, Paper; Humans; Phenylalanine; Time Factors; Tyrosine | 1974 |
Syntheses of [Phe(4NO-2)5, Tyr(Me)8]- and [Tyr(Me)5, Phe(4NO-2)8]- bradykinin.
Topics: Bradykinin; Nitrates; Phenylalanine; Tyrosine | 1974 |
Regulation of prephenate dehydratase in Brevibacterium flavum.
Topics: Brevibacterium; Enzyme Activation; Hydro-Lyases; Hydrogen-Ion Concentration; Molecular Weight; Phenylalanine; Tryptophan; Tyrosine | 1974 |
Alpha-aminocyclic and bicyclic alkane carboxylic acids: differential effects on selected amino acids of rat brain cortex.
Topics: Amines; Amino Acids; Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carboxylic Acids; Cerebral Cortex; Cyclohexanecarboxylic Acids; Cycloparaffins; Cysteine; Isoleucine; Male; Methionine; Phenylalanine; Rats; Structure-Activity Relationship; Time Factors; Tyrosine; Valine | 1974 |
Synthetic study of the effect of tyrosine at position 120 of ribonuclease.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Artiodactyla; Cattle; Chromatography, Thin Layer; Electrophoresis; Pancreas; Peptide Fragments; Phenylalanine; Ribonucleases; Temperature; Tyrosine | 1974 |
Variations in L-dopa absorption. Report of a parkinsonian patient with high plasma dopa concentration after therapeutical L-dopa dose.
Topics: Administration, Oral; Aged; Carbon Radioisotopes; Decarboxylation; Dihydroxyphenylalanine; Dopamine; Female; Humans; Injections, Intravenous; Levodopa; Male; Middle Aged; Parkinson Disease; Phenylalanine; Stimulation, Chemical; Sulfates; Tyrosine | 1974 |
Distribution and metabolism of phenylalanine and tyrosine during tualraemia in the rat.
Topics: Animals; Liver; Male; Muscles; Phenylalanine; Phenylalanine Hydroxylase; Rats; Tularemia; Tyrosine | 1974 |
[Value of the assay of urine ortho-hydroxyphenylacetic acid in hyperphenylalaninemia].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child, Preschool; Chromatography, Thin Layer; Creatinine; Diagnosis, Differential; Female; Humans; Infant; Infant, Newborn; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Tyrosine | 1974 |
Effects of cation binding on the conformation of calsequestrin and the high affinity calcium-binding protein of sarcoplasmic reticulum.
Topics: Animals; Calcium; Circular Dichroism; Hydrogen-Ion Concentration; Muscle Proteins; Muscles; Osmolar Concentration; Phenylalanine; Protein Binding; Protein Conformation; Rabbits; Sarcoplasmic Reticulum; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1974 |
[Destiny of the matrix of preserved middle-ear cartilage homografts. Experimental autoradiographic study].
Topics: Animals; Autoradiography; Cartilage; Connective Tissue; Phenylalanine; Rabbits; Ribs; Time Factors; Tissue Preservation; Transplantation, Homologous; Tritium; Tympanoplasty; Tyrosine | 1974 |
The effects of phenylalanine ammonia-lyase on leukemic lymphocytes in vitro.
Topics: Animals; Cells, Cultured; Cinnamates; Deamination; Depression, Chemical; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia, Lymphoid; Lyases; Lymphocytes; Mice; Phenylalanine; Thymidine; Tritium; Tyrosine | 1972 |
Translation of messenger RNA for histones from HeLa cells by a cell-free extract from mouse ascites tumor.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell Fractionation; Cell-Free System; Electrophoresis, Disc; Electrophoresis, Paper; HeLa Cells; Histones; Humans; Lysine; Methods; Mice; Neoplasms, Experimental; Phenylalanine; RNA, Messenger; RNA, Neoplasm; Tritium; Trypsin; Tryptophan; Tyrosine | 1972 |
X-ray diffraction and nuclear magnetic resonance dispersion studies on derivatives of carboxypeptidase A.
Topics: Binding Sites; Carboxypeptidases; Catalysis; Glutamates; Glycine; Histidine; Hydrogen-Ion Concentration; Lactates; Magnetic Resonance Spectroscopy; Models, Structural; Phenylalanine; Protein Binding; Stereoisomerism; Tyrosine; Water; X-Ray Diffraction; Zinc | 1972 |
-Chymotrypsin: what can we learn about catalysis from x-ray diffraction?
Topics: Acetates; Acridines; Acylation; Benzyl Compounds; Binding Sites; Catalysis; Chymotrypsin; Formates; Histidine; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Methylation; Models, Structural; Nitrophenols; Phenylalanine; Protein Conformation; Spectrophotometry; Structure-Activity Relationship; Tryptophan; Tyrosine; X-Ray Diffraction | 1972 |
Cell-free synthesis of histones directed by messenger RNA from sea urchin embryos.
Topics: Amino Acids; Animals; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Electrophoresis, Polyacrylamide Gel; Embryo, Nonmammalian; Histones; Peptides; Phenylalanine; Protein Biosynthesis; RNA, Messenger; Sea Urchins; Tritium; Trypsin; Tryptophan; Tyrosine | 1973 |
Transport of neurotransmitter precursors into cultured cells.
Topics: Acetylcholine; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Catecholamines; Cell Line; Cells, Cultured; Choline; Clone Cells; Glycine; Kinetics; Leucine; Mice; Neuroblastoma; Neurons; Phenylalanine; Taurine; Tritium; Tryptophan; Tyrosine | 1973 |
An in vitro evaluation of the chemotherapeutic potency of phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Animals; Diet; Evaluation Studies as Topic; Leukemia, Experimental; Leukemia, Lymphoid; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Phenylalanine; Tyrosine; Yeasts | 1973 |
High-resolution proton magnetic resonance studies of two trypsin inhibitors: soybean trypsin inhibitor (Kunitz) and ovomucoid (hen egg white).
Topics: Binding Sites; Computers; Deuterium; Egg Proteins; Egg White; Glycine; Glycine max; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Phenylalanine; Protein Binding; Protein Conformation; Trypsin Inhibitors; Tyrosine | 1973 |
Horse hemoglobin polymorphism.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Animals; Biological Evolution; Electrophoresis, Starch Gel; Female; Genetic Linkage; Genotype; Geography; Hemoglobins; Horses; Male; Pedigree; Perissodactyla; Phenotype; Phenylalanine; Polymorphism, Genetic; Species Specificity; Tyrosine | 1974 |
Biochemical studies in a patient with "tyrosinosis".
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Humans; Male; Phenols; Phenylalanine; Tyrosine | 1974 |
Narcolepsy and cataplexy. Clinical features, treatment and cerebrospinal fluid findings.
Topics: Adult; Amphetamine; Aspartic Acid; Body Weight; Cataplexy; Cerebrospinal Fluid Proteins; Dextroamphetamine; Electroencephalography; Feeding and Eating Disorders; Female; Homovanillic Acid; Humans; Libido; Male; Mental Disorders; Methionine; Middle Aged; Narcolepsy; Phenylalanine; Syndrome; Tyrosine | 1974 |
Platelet transaminase.
Topics: 5-Hydroxytryptophan; Acetates; Amination; Amino Acids; Aminobutyrates; Aspartic Acid; Blood Platelets; Carbon Isotopes; Glutamates; Glycolates; Humans; Hydroxylamines; Kinetics; Leucine; Phenylalanine; Transaminases; Tyrosine | 1972 |
Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition.
Topics: Alanine; Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; B-Lymphocytes; Glutamates; Hemagglutination Tests; Immunization; Immunogenetics; Lysine; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Peptide Chain Termination, Translational; Peptides; Phenylalanine; Poly A-U; Proline; T-Lymphocytes; Tyrosine | 1973 |
Comparative Arrhenius plots of enzyme activity from Penicillium.
Topics: Cell-Free System; Cyclohexanecarboxylic Acids; Drug Stability; Enzyme Activation; Glutathione Reductase; Leucovorin; Ligases; Penicillium; Phenylalanine; Phosphotransferases; Species Specificity; Spectrophotometry; Statistics as Topic; Temperature; Tryptophan; Tyrosine | 1973 |
Phenylalanine hydroxylase activity in a mutant of Geotrichum candidum.
Topics: Carbon Radioisotopes; Cell-Free System; Culture Media; Dialysis; Mitosporic Fungi; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1974 |
Amino-enzyme intermediates in pepsin-catalyzed reactions.
Topics: Catalysis; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Dipeptides; Electrophoresis, Paper; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Mathematics; Oxygen Isotopes; Pepsin A; Peptides; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1972 |
Studies on the catalytic mechanism of pepsin using a new synthetic substrate.
Topics: Acetophenones; Animals; Azo Compounds; Bromine; Catalysis; Deuterium; Endopeptidases; Fluoroacetates; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Pepsin A; Phenylalanine; Protein Binding; Structure-Activity Relationship; Swine; Tryptophan; Tyrosine | 1972 |
Conformational changes of transfer ribonucleic acid. Equilibrium phase diagrams.
Topics: Buffers; Chemical Phenomena; Chemistry, Physical; Dialysis; Drug Stability; Escherichia coli; Formates; Genetic Code; Magnesium; Methionine; Models, Chemical; Models, Structural; Nucleic Acid Conformation; Nucleic Acid Denaturation; Nucleic Acid Renaturation; Osmolar Concentration; Phenylalanine; RNA, Bacterial; RNA, Transfer; Sodium; Spectrophotometry, Ultraviolet; Temperature; Thiouridine; Time Factors; Tyrosine; Valine | 1972 |
Fluorescence studies on substrate binding to seryl-tRNA synthetase from yeast.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Binding Sites; Cytosine Nucleotides; Kinetics; Methods; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Serine; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan; Tyrosine | 1972 |
Large scale purification of tRNA ser , tRNA tyr and tRNA phe from Baker's yeast.
Topics: Acylation; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Chelating Agents; Chromatography, Ion Exchange; Cytosine Nucleotides; Electrophoresis, Polyacrylamide Gel; Nucleotidyltransferases; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Serine; Tyrosine; Urea | 1972 |
The change in optical activity of amino acid-specific Escherichia coli transfer RNA containing 4-thiouridylate by chemical modifications.
Topics: Arginine; Benzyl Compounds; Chemical Phenomena; Chemistry; Circular Dichroism; Cyanogen Bromide; Escherichia coli; Iodine; Methionine; Optical Rotation; Oxidation-Reduction; Phenylalanine; RNA, Transfer; Thioridazine; Thiourea; Tyrosine; Ultraviolet Rays; Valine | 1972 |
Characterization of a mouse ascites cell-free system.
Topics: Animals; Carcinoma, Krebs 2; Cell-Free System; Escherichia coli; Globins; HeLa Cells; Histones; Kinetics; Lysine; Magnesium; Mice; Osmolar Concentration; Peptide Biosynthesis; Phenylalanine; Protein Biosynthesis; RNA, Bacterial; RNA, Messenger; RNA, Neoplasm; RNA, Ribosomal; Sea Urchins; Tritium; Tryptophan; Tyrosine | 1972 |
Effect of increasing chain length of AA-oligonucleotide acceptors on their reactivity at the peptidyl transferase center in ribosomes and polysomes.
Topics: Acetyltransferases; Amino Acids; Binding Sites; Carbon Isotopes; Cytoplasm; Escherichia coli; Genetic Code; Kinetics; Nucleotides; Oligonucleotides; Peptide Chain Elongation, Translational; Peptides; Phenylalanine; Polyribosomes; Protein Conformation; Ribonucleases; Ribosomes; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Tritium; Tyrosine | 1972 |
Crystallization of pure species of bacterial tRNA for x-ray diffraction studies.
Topics: Chemical Precipitation; Crystallization; Dialysis; Diffusion; Escherichia coli; Methionine; Methods; Phenylalanine; Photography; RNA, Bacterial; RNA, Transfer; Spermine; Tyrosine; X-Ray Diffraction | 1972 |
[Fate of cialite preserved homologous transplants in the middle ear. Autoradiographic studies of fascia and bone].
Topics: Animals; Autoradiography; Benzoxazoles; Bone Regeneration; Bone Transplantation; Ethylmercury Compounds; Fascia; Methods; Phenylalanine; Rabbits; Tissue Preservation; Transplantation, Homologous; Tritium; Tyrosine | 1972 |
Reversal by aromatic amino acids of 2-thiazole-DL-alanine inhibition of Salmonella typhimurium.
Topics: Amino Acids; Cell-Free System; Enzyme Repression; Feedback; Histidine; Hydro-Lyases; Membrane Transport Proteins; Phenylalanine; Salmonella typhimurium; Spectrophotometry; Stereoisomerism; Thiazoles; Tryptophan; Tyrosine | 1973 |
5S rRNA and t RNA: evidence for a common evolutionary origin.
Topics: Animals; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Genetic Code; Glutamine; Models, Biological; Nucleotides; Phenylalanine; Rats; RNA, Ribosomal; RNA, Transfer; Saccharomyces cerevisiae; Serine; Triticum; Tyrosine | 1973 |
Mutant tyrosine transfer RNA that can be charged with glutamine.
Topics: Amino Acid Sequence; Amino Acyl-tRNA Synthetases; Base Sequence; Carbon Isotopes; Coliphages; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Genetic Code; Glutamine; Lysogeny; Models, Structural; Mutation; Nucleotides; Phenylalanine; Phosphorus Isotopes; RNA, Transfer; Suppression, Genetic; Transduction, Genetic; Tyrosine; Viral Proteins | 1973 |
Regulatory gene of phenylalanine biosynthesis (pheR) in Salmonella typhimurium.
Topics: Aldehyde-Lyases; Cell-Free System; Chromatography, DEAE-Cellulose; Chromosome Mapping; Conjugation, Genetic; Cyclohexanecarboxylic Acids; Cyclohexanes; Drug Resistance, Microbial; Fluorine; Genes, Regulator; Heptoses; Hydro-Lyases; Mutation; Oxidoreductases; Phenylalanine; Phosphotransferases; Pyruvates; Salmonella typhimurium; Tetroses; Transduction, Genetic; Tyrosine | 1973 |
Analysis of the binding of phenylalanine to phenylalanyl-tRNA synthetase.
Topics: Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Benzyl Compounds; Chromatography, Thin Layer; Escherichia coli; Glycine; Kinetics; Magnesium; Phenylalanine; Phosphorus Isotopes; Protein Binding; Protein Conformation; Thermodynamics; Transfer RNA Aminoacylation; Tritium; Tyrosine | 1973 |
Tryptophol formation by Zygosaccharomyces priorianus.
Topics: 5-Hydroxytryptophan; Acetaldehyde; Amino Alcohols; Chromatography, Thin Layer; Fermentation; Fluorometry; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Phenylalanine; Pyruvates; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Stereoisomerism; Tryptamines; Tryptophan; Tyrosine | 1973 |
Regulation of tyrosine and phenylalanine biosynthesis in Escherichia coli K-12: properties of the tyrR gene product.
Topics: Aldehyde-Lyases; Bacterial Proteins; Cell-Free System; Coliphages; Drug Resistance, Microbial; Enzyme Repression; Escherichia coli; Fluorine; Genes, Regulator; Heptoses; Isoenzymes; Lysogeny; Mutagens; Mutation; Nitrosoguanidines; Phenylalanine; Temperature; Tetroses; Transduction, Genetic; Tyrosine | 1973 |
Tyrosine and phenylalanine biosynthesis in Escherichia coli K-12: complementation between different tyrR alleles.
Topics: Aldehyde-Lyases; Alleles; Cell-Free System; Diploidy; Enzyme Repression; Escherichia coli; Genes, Regulator; Genetic Complementation Test; Heptoses; Isoenzymes; Mutation; Phenylalanine; Tetroses; Transduction, Genetic; Tyrosine | 1973 |
Amino acid acceptor stem of E. coli suppressor tRNA tyr is a site of synthetase recognition.
Topics: Alleles; Amino Acids; Amino Acyl-tRNA Synthetases; Base Sequence; Binding Sites; Carbon Isotopes; Coliphages; Electrophoresis; Escherichia coli; Genetic Code; Glutamine; Lysogeny; Mutation; Oligonucleotides; Phenylalanine; RNA, Transfer; Suppression, Genetic; Transduction, Genetic; Tyrosine | 1973 |
Modification of carboxyl groups in pepsin.
Topics: Alanine; Amines; Animals; Aspartic Acid; Carbodiimides; Chemical Phenomena; Chemistry; Glutamates; Hemoglobins; Hydrogen-Ion Concentration; Morpholines; Nitrobenzenes; Pepsin A; Phenylalanine; Protein Binding; Structure-Activity Relationship; Swine; Tosyl Compounds; Tyrosine | 1973 |
Studies on the metabolism of phenylalanine and tyrosine in patients with renal disease.
Topics: Adult; Amino Acids; Analysis of Variance; Chromatography, Paper; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Transplantation; Liver Function Tests; Male; Middle Aged; Phenylalanine; Renal Dialysis; Time Factors; Tyrosine | 1973 |
Chemical and enzymatic modification of proteins in the 30 S ribosome of Escherichia coli.
Topics: Bacterial Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Iodine; Iodine Isotopes; Kinetics; Peroxidases; Phenylalanine; Protein Binding; Ribosomes; Tyrosine | 1973 |
Cobalt substituted zinc metalloenzymes.
Topics: Alcohol Oxidoreductases; Alkaline Phosphatase; Animals; Apoproteins; Cadmium; Carboxypeptidases; Circular Dichroism; Cobalt; Enzyme Activation; Enzymes; Escherichia coli; Horses; Hydrogen-Ion Concentration; Liver; Metalloproteins; Phenylalanine; Spectrophotometry; Structure-Activity Relationship; Tyrosine; Zinc | 1973 |
Structure-function relations in tRNA.
Topics: Base Sequence; Crystallography; Escherichia coli; Methionine; Models, Structural; Nucleic Acid Conformation; Phenylalanine; Plants; Ribonucleotides; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Species Specificity; Structure-Activity Relationship; Tyrosine; X-Ray Diffraction | 1973 |
[Phenylalanine concentration in the intestinal fluid of hyperphenylalaninemic patient].
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Humans; Infant; Intestinal Absorption; Intestinal Secretions; Phenylalanine; Tyrosine | 1973 |
High-resolution NMR investigation of base pairing structure of transfer RNA.
Topics: Arginine; Base Sequence; Binding Sites; Chromatography, Gel; Escherichia coli; Glutamates; Hot Temperature; Magnetic Resonance Spectroscopy; Methionine; Nucleic Acid Conformation; Oligonucleotides; Phenylalanine; Ribonucleases; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine | 1973 |
Unfolding of yeast transfer ribonucleic acid species caused by addition of organic solvents and studied by circular dichroism.
Topics: Arsenicals; Buffers; Circular Dichroism; Crystallization; Dioxins; Ethanol; Glycols; Hexanols; Isoleucine; Magnesium; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Serine; Sodium Chloride; Spectrophotometry, Ultraviolet; Spermidine; Spermine; Temperature; Tyrosine; Urea; Valine | 1974 |
A deae-cellulose filter disk assay for aminoacyl-tRNA.
Topics: Acetates; Alanine; Amino Acyl-tRNA Synthetases; Aspartic Acid; Cellulose; Citrates; Electrophoresis, Disc; Escherichia coli; Evaluation Studies as Topic; Filtration; Glutamates; Glycine; Isoleucine; Lysine; Methionine; Methods; Microchemistry; Phenylalanine; Phosphates; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Tritium; Tyrosine; Valine | 1974 |
Effect of inhibitors of protein synthesis on the formation of phenols derived from acetate and shikimic acid in Aspergillus fumigatus.
Topics: Acetates; Aspergillus fumigatus; Azaguanine; Benzoates; Benzyl Compounds; Culture Media; Cycloheximide; Fluorine; Fungal Proteins; Nitriles; Phenols; Phenylalanine; Phenylpyruvic Acids; Shikimic Acid; Toluene; Tryptophan; Tyrosine | 1974 |
Feedback-insensitive mutants of the gene for the tyrosine-inhibited DAHP synthetase in yeast.
Topics: Aldehyde-Lyases; Chromosome Mapping; Crosses, Genetic; Feedback; Genes; Heptoses; Meiosis; Mutation; Phenotype; Phenylalanine; Phosphoenolpyruvate; Recombination, Genetic; Saccharomyces cerevisiae; Tetroses; Tyrosine | 1974 |
Changes in levels of amino acid acceptors in tRNA from Escherichia coli grown under various conditions.
Topics: Amino Acyl-tRNA Synthetases; Aminobutyrates; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Densitometry; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorine; Mutation; Organophosphonates; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Temperature; Threonine; Time Factors; Transfer RNA Aminoacylation; Tyrosine; Valine | 1974 |
Isolation, purification, and methylation of undermethylated tRNA Phe from an RC rel mutant of Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Escherichia coli; Evaluation Studies as Topic; Leucine; Methods; Methylation; Mutation; Phenylalanine; RNA, Bacterial; RNA, Transfer; S-Adenosylmethionine; Spectrophotometry, Ultraviolet; Sulfur Radioisotopes; tRNA Methyltransferases; Tyrosine | 1974 |
Nucleotide sequences of transfer ribonucleic acids.
Topics: Alanine; Arginine; Aspartic Acid; Base Sequence; Biological Evolution; Escherichia coli; Evaluation Studies as Topic; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Serine; Species Specificity; Tryptophan; Tyrosine; Valine | 1974 |
Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-L-methionine. II. Aromatic amino acids.
Topics: Adenosine; Amino Acids; Animals; Electron Transport; Escherichia coli; Homocysteine; Homoserine; Hydrolysis; Liver; Malonates; Methionine; Molecular Conformation; Nitro Compounds; Phenylalanine; Rats; S-Adenosylmethionine; Structure-Activity Relationship; Transferases; Tyrosine; Valerates; Yeasts | 1974 |
Structure-activity relationships of puromycin analogues on Escherichia coli polysomes.
Topics: Benzyl Compounds; Escherichia coli; Glycine; Kinetics; Leucine; Peptides; Phenylalanine; Polyribosomes; Puromycin; Receptors, Drug; Structure-Activity Relationship; Tritium; Tyrosine | 1974 |
The fate of bone transplants in the middle ear. An autoradiographic study in rabbits.
Topics: Animals; Autoradiography; Bone and Bones; Bone Development; Bone Transplantation; Cell Nucleus; Collagen; Ear, Middle; Femur; Humerus; Osteoblasts; Osteocytes; Phenylalanine; Protein Biosynthesis; Rabbits; Tibia; Transplantation, Homologous; Tritium; Tyrosine | 1974 |
Kinetics of pepsin-catalysed transpeptidation: evidence for the 'amino-enzyme' intermediate.
Topics: Acyltransferases; Animals; Binding Sites; Chromatography, DEAE-Cellulose; Hydrolysis; Kinetics; Mathematics; Nitro Compounds; Optical Rotation; Pepsin A; Phenylalanine; Protein Binding; Spectrophotometry, Ultraviolet; Swine; Time Factors; Tyrosine | 1974 |
False neurotransmitters and hepatic coma.
Topics: Amines; Animals; Brain; Dihydroxyphenylalanine; Female; Hepatic Encephalopathy; Humans; Intestinal Mucosa; Kanamycin; Ligation; Liver; Motor Activity; Myocardium; Norepinephrine; Octopamine; Phenylalanine; Rats; Serotonin; Tyramine; Tyrosine | 1974 |
An alternative mechanism for beneficial effects of intestinal sterilization in hepatic encephalopathy.
Topics: Animals; Brain Chemistry; Female; Hepatic Encephalopathy; Kanamycin; Norepinephrine; Octopamine; Phenylalanine; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tyrosine | 1974 |
Comparative specificity of microbial acid proteinases for synthetic peptides. Primary specificity with Z-tetrapeptides.
Topics: Alanine; Aspergillus; Chromatography, Paper; Crystallization; Densitometry; Leucine; Lysine; Mitosporic Fungi; Mucor; Oligopeptides; Pepsin A; Peptide Hydrolases; Phenylalanine; Rhizopus; Species Specificity; Structure-Activity Relationship; Tyrosine | 1974 |
Isolation of DAHP synthetase by tyrosine-affinity chromatography.
Topics: Aldehyde-Lyases; Chromatography, Affinity; Heptoses; Methods; Phenylalanine; Phosphoenolpyruvate; Saccharomyces cerevisiae; Sepharose; Tetroses; Tyrosine | 1974 |
Significance of altered carbon flow in aromatic amino acid synthesis: an approach to the isolation of regulatory mutants in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acids; Biological Assay; Carbon; Cell-Free System; Culture Media; Cyclohexanecarboxylic Acids; Drug Resistance, Microbial; Fluorine; Fluorometry; Fructose; Genetics, Microbial; Hydro-Lyases; Leuconostoc; Methods; Mutation; ortho-Aminobenzoates; Pentosyltransferases; Phenylalanine; Pseudomonas aeruginosa; Transaminases; Tryptophan; Tyrosine | 1972 |
Feedback regulation of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetase from a marine bacterium, Vibrio MB22.
Topics: Aldehyde-Lyases; Carbon Isotopes; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Cobalt; Culture Media; Cyclohexanecarboxylic Acids; Edetic Acid; Feedback; Heptoses; Isoenzymes; Marine Biology; Phenylalanine; Seawater; Tetroses; Tryptophan; Tyrosine; Vibrio; Water Microbiology | 1972 |
Formation of catechol compounds from phenylalanine and tyrosine with isolated nerve endings.
Topics: Animals; Brain; Catecholamines; Cats; Guinea Pigs; Haplorhini; Hydroxylation; Kinetics; Membranes; Mice; Nerve Endings; Phenylalanine; Phenylalanine Hydroxylase; Rats; Synaptosomes; Tritium; Tyrosine | 1972 |
Evidence of phenylalanine transaminase activity in the isoenzymes of aspartate transaminase.
Topics: Animals; Aspartate Aminotransferases; Binding Sites; Brain; Carbon Isotopes; Chemical Phenomena; Chemistry; Electrophoresis, Starch Gel; Immunodiffusion; Isoenzymes; Ketoglutaric Acids; Mitochondria, Muscle; Myocardium; Phenylalanine; Phenylpyruvic Acids; Protein Binding; Pyridoxal; Pyridoxamine; Rabbits; Spectrophotometry; Subcellular Fractions; Swine; Transaminases; Tryptophan; Tyrosine; Ultraviolet Rays | 1972 |
Some regulatory properties of phospho-2-keto-3-deoxyheptonate aldolase from the blue-green alga Anacystis nidulans.
Topics: Aldehyde-Lyases; Allosteric Regulation; Ammonium Sulfate; Chromatography, Gel; Culture Media; Cyanobacteria; Feedback; Heptoses; Kinetics; Phenylalanine; Phosphoenolpyruvate; Protamines; Protein Binding; Structure-Activity Relationship; Sulfuric Acids; Tetroses; Tryptophan; Tyrosine | 1972 |
Studies on candicidin biogenesis.
Topics: Acetates; Amino Acids; Aminobenzoates; Antifungal Agents; Culture Media; Depression, Chemical; Fermentation; Glucose; Methionine; Phenylalanine; Shikimic Acid; Streptomyces; Streptomyces griseus; Tryptophan; Tyrosine | 1972 |
Properties of tyrosyl transfer ribonucleic acid synthetase from two tyrS mutants of Escherichia coli K-12.
Topics: Amino Acyl-tRNA Synthetases; Chromatography; Drug Stability; Escherichia coli; Genes; Hot Temperature; Immune Sera; Immunoassay; Immunodiffusion; Kinetics; Mutation; Phenotype; Phenylalanine; Phosphorus Isotopes; Solubility; Transduction, Genetic; Trichloroacetic Acid; Tyrosine | 1972 |
Genetic analysis of phenylalanine-responding mutants of Pseudomonas aeruginosa.
Topics: Cell-Free System; Culture Media; Cyclohexanecarboxylic Acids; Cyclohexanes; Genes; Hydro-Lyases; Mutagens; Mutation; Nitrosoguanidines; Phenylalanine; Pseudomonas aeruginosa; Pyruvates; Recombination, Genetic; Shikimic Acid; Spectrophotometry; Transaminases; Transduction, Genetic; Tryptophan; Tyrosine | 1972 |
Channel-shuttle mechanism for the regulation of phenylalanine and tyrosine synthesis at a metabolic branch point in Pseudomonas aeruginosa.
Topics: Aldehyde-Lyases; Allosteric Regulation; Cell-Free System; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclohexanecarboxylic Acids; Cyclohexanes; Hydro-Lyases; Models, Chemical; Molecular Weight; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Phosphotransferases; Pseudomonas aeruginosa; Pyruvates; Tyrosine | 1973 |
Human carbonic anhydrases. X. Preparation of large peptide fragments of carbonic anhydrase B used for sequence studies.
Topics: Amino Acid Sequence; Amino Acids; Arginine; Carbonic Anhydrases; Chromatography, Gel; Cyanogen Bromide; Cysteine; Erythrocytes; Freeze Drying; Guanidines; Humans; Hydrogen-Ion Concentration; Lysine; Methionine; Peptides; Phenylalanine; Solubility; Spectrophotometry, Ultraviolet; Trypsin; Tryptophan; Tyrosine | 1973 |
Peptide aldehydes inhibiting chymotrypsin.
Topics: Acetates; Aldehydes; Benzyl Compounds; Butanones; Chemical Phenomena; Chemistry; Chymotrypsin; Formates; Imidazoles; Kinetics; Leucine; Oxidation-Reduction; Peptides; Phenethylamines; Phenylalanine; Structure-Activity Relationship; Succinimides; Tryptophan; Tyrosine | 1972 |
[Tyrosinosis. Primary and secondary biochemical changes].
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diet Therapy; Glucagon; Glucose; Humans; Hypoglycemia; Infant; Infant, Newborn; Liver Function Tests; Methionine; Phenylalanine; Phosphates; Protein Biosynthesis; Rickets; Statistics as Topic; Thrombocytopenia; Time Factors; Tyrosine; Vomiting | 1972 |
The effects of high phenylalanine concentrations on serotonin and catecholamine metabolism in the human brain.
Topics: Adolescent; Adult; Amino Acids; Brain; Catecholamines; Chromatography; Dopamine; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Phenylacetates; Phenylalanine; Phenylketonurias; Probenecid; Serotonin; Tryptophan; Tyrosine | 1972 |
Amino acid uptake by Xenopus laevis embryos: effect of triiodo-L-thyronine.
Topics: Amino Acids; Animals; Carbon Isotopes; Female; Glycine; Lysine; Male; Metamorphosis, Biological; Methionine; Phenylalanine; Scintillation Counting; Time Factors; Triiodothyronine; Tritium; Tryptophan; Tyrosine; Xenopus | 1972 |
The phenylalanine and tyrosine requirements and their interrelationship for the young chick.
Topics: Animals; Body Weight; Chickens; Diet; Growth; Male; Nutritional Requirements; Phenylalanine; Tyrosine | 1972 |
[Amino acids in the intestinal fluid in a subject with high blood phenylalanine. Comparative study with a control group].
Topics: Amino Acids; Child, Preschool; Chromatography, Ion Exchange; Duodenum; Humans; Infant; Infant, Newborn; Intestinal Secretions; Intubation, Gastrointestinal; Phenylalanine; Phenylketonurias; Tyrosine | 1972 |
Assimilation and toxicity of exogenous amino acids in the methane-oxidizing bacterium Methylococcus capsulatus.
Topics: Amino Acids; Aspartic Acid; Bacteria; Carbon Isotopes; Histidine; Homoserine; Lysine; Methionine; Phenylalanine; Threonine; Tyrosine | 1972 |
[Blood-brain barrier and placental barrier for various amino acids in the mouse (whole body autoradiography studies)].
Topics: Alanine; Amino Acids; Animals; Autoradiography; Blood-Brain Barrier; Cell Membrane Permeability; Female; Glycine; Lysine; Male; Maternal-Fetal Exchange; Mice; Mice, Inbred Strains; Phenylalanine; Pregnancy; Serine; Tritium; Tyrosine | 1972 |
Amino acid compositions of all the tryptic peptides from the and polypeptide chains of adult hemoglobin of the slow loris (Nycticebus coucang). Biochemical studies on hemoglobins and myoglobins. X.
Topics: Alanine; Amino Acids; Animals; Arginine; Chromatography; Chromatography, Paper; Glutamine; Hemoglobins; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myoglobin; Peptides; Phenylalanine; Primates; Serine; Threonine; Trypsin; Tyrosine; Valine | 1972 |
Plasma amino acid abnormalities in chronic renal failure.
Topics: Adult; Amino Acids; Cysteine; Cystine; Disulfides; Female; Homocysteine; Humans; Kidney Failure, Chronic; Male; Methionine; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine | 1972 |
Pathogenesis of phenylketonuria: inhibition of DOPA and catecholamine synthesis in patients with phenylketonuria.
Topics: Amino Acid Metabolism, Inborn Errors; Catecholamines; Catechols; Child; Child, Preschool; Deuterium; Dihydroxyphenylalanine; Dopamine; Glycols; Homovanillic Acid; Humans; Mass Spectrometry; Phenylalanine; Phenylketonurias; Tyrosine; Vanilmandelic Acid | 1972 |
Enzyme-mediated binding of tyrosine to brome-mosaic-virus ribonucleic acid.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Centrifugation, Density Gradient; Cystine; Enzyme Induction; Glycine; Hydrogen-Ion Concentration; Methods; Mosaic Viruses; Phenylalanine; Plant Viruses; RNA, Viral; Tritium; Tyrosine | 1972 |
[Methionine toxicity. 5. Amino acid content of blood serum and urine after high doses of methionine and gaseous elimination of 35S from 35S methionine].
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Glutathione; Glycine; Histidine; Lysine; Methionine; Phenylalanine; Rats; Sulfur Isotopes; Taurine; Threonine; Time Factors; Tyrosine | 1972 |
The chemical composition of wool. XI. Separation and analysis of exocuticle and endocuticle.
Topics: Amino Acids; Animals; Aspartic Acid; Coloring Agents; Cysteine; Cystine; Formates; Histidine; Leucine; Lysine; Methionine; Microscopy, Electron; Phenylalanine; Proline; Pronase; Sheep; Structure-Activity Relationship; Threonine; Tyrosine; Wool | 1972 |
[Effect of a protein-deficient diet on certain biochemical parameters of rat liver cell fractions. 1. Content in free amino acids].
Topics: Amino Acids; Animals; Autoanalysis; Blood Chemical Analysis; Cell Fractionation; Dietary Proteins; Isoleucine; Leucine; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Phenylalanine; Rats; Rats, Inbred Strains; Subcellular Fractions; Tyrosine; Valine | 1972 |
[Diagnostic and therapeutic problems of phenylketonuria. Parallel study of 2 familial cases as a function of treatment].
Topics: Child, Preschool; Chromatography, DEAE-Cellulose; Diet Therapy; Humans; Infant; Male; Pedigree; Phenylalanine; Phenylketonurias; Tyrosine | 1972 |
[The interrelations between the metabolism of gamma-amino butyric acid and tyrosine in the brain and liver of rats].
Topics: Aminobutyrates; Animals; Brain; Brain Chemistry; Liver; Phenylalanine; Rats; Tyrosine | 1972 |
Diet and aminoacids in uraemia.
Topics: Amino Acids; Amino Acids, Essential; Carbon Radioisotopes; Diet; Dietary Proteins; Glycine; Humans; Nitrogen; Nitrogen Isotopes; Phenylalanine; Potassium; Radioisotopes; Renal Dialysis; Tyrosine; Urea; Uremia; Valine | 1972 |
The free amino acid pattern of the intestinal contents of chicks fed raw and heated soybean meal.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Chickens; Coronary Vessels; Cystine; Diet; Dietary Proteins; Electrophoresis, Disc; Glycine max; Hot Temperature; Intestine, Small; Isoleucine; Leucine; Methionine; Nitrogen; Phenylalanine; Plant Proteins; Portal Vein; Solubility; Tyrosine; Ultrafiltration; Valine | 1972 |
[2 new cases of microcephalic children with intrauterine growth retardation born of phenylketonuric mothers].
Topics: Birth Weight; Chromatography, Ion Exchange; Female; Growth Disorders; Humans; Infant; Male; Mental Disorders; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1972 |
Toxic effects of aromatic amino acids on the livability of bull spermatozoa.
Topics: Animals; Catalase; Cattle; Cell Survival; Dialysis; Egg Yolk; Female; Hydrogen Peroxide; In Vitro Techniques; Male; Phenylalanine; Quaternary Ammonium Compounds; Spermatozoa; Stereoisomerism; Tryptophan; Tyrosine | 1972 |
Studies on the low molecular weight protein of myosin.
Topics: Amino Acids; Animals; Chickens; Electrophoresis, Disc; Gels; Molecular Weight; Myosins; Phenylalanine; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Urea | 1972 |
Amino acid metabolism in plants. 3. Purification and some properties of a multispecific aminotransferase isolated from bushbean seedlings (Phaseolus vulgaris L.).
Topics: Ammonium Sulfate; Aspartic Acid; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Darkness; Electrophoresis; Glutamates; Hydrogen-Ion Concentration; Ketoglutaric Acids; Light; Molecular Weight; Oxaloacetates; Phenylalanine; Plant Cells; Plant Development; Plants; Radiation Effects; Structure-Activity Relationship; Subcellular Fractions; Transaminases; Tyrosine | 1972 |
Clinical significance of tyrosinemia of prematurity.
Topics: Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Child Development; Chromatography, Paper; Diet Therapy; Fatigue; Feeding Behavior; Female; Growth Disorders; Humans; Infant, Newborn; Infant, Premature, Diseases; Intelligence; Intelligence Tests; Phenylalanine; Pregnancy; Pregnancy Complications; Tyrosine | 1973 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
A complex of histones IIb2 and IV.
Topics: Arsenicals; Buffers; Chemical Phenomena; Chemistry; Chromatin; Circular Dichroism; Computers; Histones; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Osmolar Concentration; Phenylalanine; Phosphates; Protein Conformation; Sodium; Sodium Chloride; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tyrosine; Water | 1973 |
Fluorimetric measurement of the phenylalanine content of human granulocytes.
Topics: Amino Acids; Buffers; Copper; Erythrocytes; Female; Filtration; Fluorometry; Humans; Hydrogen-Ion Concentration; Indicators and Reagents; Leukocytes; Male; Peptides; Phenylalanine; Spectrometry, Fluorescence; Time Factors; Trichloroacetic Acid; Tryptophan; Tyrosine | 1973 |
Surface binding of amino acids by L1210 cells at 4 degrees C.
Topics: Alanine; Amino Acids; Animals; Binding Sites; Biological Transport, Active; Cell Line; Cell Membrane; Histidine; Hydrogen-Ion Concentration; Hydroxylation; Isoleucine; Leucine; Leukemia L1210; Lipids; Mice; Phenylalanine; Solubility; Structure-Activity Relationship; Threonine; Tyrosine; Water | 1973 |
Some physicochemical and chemical properties of light chains isolated from rabbit cardiac myosin.
Topics: Amino Acids; Ammonium Sulfate; Animals; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Heart Ventricles; Molecular Weight; Myocardium; Myosins; Peptides; Phenylalanine; Rabbits; Sodium Dodecyl Sulfate; Spectrophotometry, Ultraviolet; Tyrosine; Ultracentrifugation | 1973 |
Amino acid metabolism in plants. IV. Kinetic studies with a multispecific aminotransferase purified from bushbean seedlings (Phaseolus vulgaris L.).
Topics: Amino Acids; Aspartic Acid; Binding, Competitive; Dopamine; Enzyme Activation; Glutamates; Ketoglutaric Acids; Kinetics; Phenylalanine; Plants; Time Factors; Transaminases; Tryptophan; Tyrosine | 1973 |
Effects of amino acids on the isolated chicken retina, and on its response to glutamate stimulation.
Topics: Amino Acids; Aminobutyrates; Animals; Arginine; Carbon Isotopes; Chickens; Chromatography, Paper; Citrulline; Cortical Spreading Depression; Glutamates; Glutarates; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Perfusion; Phenylalanine; Retina; Sclera; Taurine; Tryptophan; Tyrosine | 1973 |
Stereospecificity of blood-brain barrier permeability to amino acids.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Rats; Threonine; Tritium; Tryptophan; Tyrosine; Valine | 1973 |
Normal development in an infant of a mother with phenylketonuria.
Topics: Black People; Child Development; Female; Humans; Infant; Intelligence; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Pregnancy Complications; Tyrosine | 1973 |
Effects of oral contraceptives and obesity on carrier tests for phenylketonuria.
Topics: Adult; Contraceptives, Oral; Fasting; Female; Heterozygote; Humans; Menstruation; Middle Aged; Obesity; Ovulation; Phenylalanine; Phenylketonurias; Pregnancy; Temperature; Time Factors; Tyrosine | 1973 |
Effect of diet on survival and nephropathy of NZB-NZW hybrid mice.
Topics: Animals; Body Weight; Diet; Female; Kidney; Male; Mice; Mice, Inbred NZB; Mice, Inbred Strains; Nephrotic Syndrome; Phenylalanine; Sex Factors; Tyrosine | 1973 |
Phenylalanine loading and aromatic acid excretion in normal subjects and heterozygotes for phenylketonuria.
Topics: Adult; Child; Chromatography, Gas; Drug Tolerance; Female; Heterozygote; Humans; Male; Mass Spectrometry; Pedigree; Phenylacetates; Phenylalanine; Phenylketonurias; Prednisolone; Time Factors; Tyrosine | 1973 |
Evidence for three isozymes of chorismate mutase in alfalfa.
Topics: Catechols; Chlorogenic Acid; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cinnamates; Coumarins; Cyclohexanecarboxylic Acids; Electrophoresis, Polyacrylamide Gel; Isoenzymes; Isomerases; Models, Biological; Molecular Weight; Multienzyme Complexes; Phenylalanine; Plant Cells; Plants; Spectrophotometry, Ultraviolet; Subcellular Fractions; Temperature; Tryptophan; Tyrosine; Vinyl Compounds | 1973 |
The reversal of triparanol-induced cataracts in the rat. 3. Amino acid content and uptake of 14 C -AIB in cataractous and clearing lenses.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cataract; Cystine; Diet; Glutamates; Glycine; Histidine; Isoleucine; Lens, Crystalline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Serine; Threonine; Triparanol; Tyrosine; Valine | 1973 |
Low plasma tryptophan levels in recently hospitalized schizophrenics.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Chronic Disease; Depression; Diet; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Schizophrenia; Sex Factors; Tryptophan; Tyrosine | 1973 |
Association of plasma tryptophan levels with clinical change in female schizophrenic patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Remission, Spontaneous; Schizophrenia; Sex Factors; Tryptophan; Tyrosine | 1973 |
Modifications of serum-free amino acid patterns of Babinga adult pygmies after short-term feeding of a balanced diet.
Topics: Adolescent; Adult; Alanine; Amino Acids; Anti-Infective Agents; Black People; Central African Republic; Diet; Dietary Fats; Dietary Proteins; Feeding Behavior; Glutamates; Glycine; Humans; Intestinal Diseases; Male; Nutritional Physiological Phenomena; Phenylalanine; Protein Deficiency; Serine; Time Factors; Tyrosine; Vitamins | 1973 |
Isolation and amino-acid sequence of the C-peptide of duck proinsulin.
Topics: Amino Acid Sequence; Animals; Autoanalysis; Biological Evolution; Carboxypeptidases; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Chymotrypsin; Ducks; Histidine; Leucyl Aminopeptidase; Pancreas; Peptides; Phenylalanine; Proinsulin; Tyrosine | 1973 |
Impairment of phenylalanine hydroxylation in chronic renal insufficiency.
Topics: Adult; Amino Acids; Animals; Chronic Disease; Female; Humans; Hydroxylation; Kidney; Kidney Failure, Chronic; Liver; Male; Middle Aged; Phenylalanine; Phenylalanine Hydroxylase; Protein Deficiency; Rats; Tyrosine; Uremia | 1973 |
Report on a cooperative study of various fluorometric procedures and the Guthrie Bacterial Inhibition Assay in the determination of hyperphenylalaninemia.
Topics: Autoanalysis; Fluorometry; Glutamates; Humans; Infant, Newborn; Infant, Premature; Microbial Sensitivity Tests; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
Analysis of the "report on a cooperative study of various fluorometric procedures and the Guthrie Bacterial Inhibition Assay in the determination of hyperphenylalaninemia" and the significance of this study in the detection, diagnosis, and management of p
Topics: Age Factors; Autoanalysis; Diet Therapy; Fluorometry; Glutamates; Glutamine; Humans; Infant Nutrition Disorders; Infant, Newborn; Infant, Premature; Metabolism, Inborn Errors; Methods; Phenylalanine; Phenylketonurias; Quality Control; Tyrosine | 1973 |
Monitoring phenylalanine-tyrosine metabolism by high-resolution liquid chromatography of urine.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autistic Disorder; Carbidopa; Catechols; Child; Chromatography, Gas; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Hippurates; Homovanillic Acid; Humans; Hyperkinesis; Intellectual Disability; Lactates; Mandelic Acids; Mass Spectrometry; Methods; Nervous System Diseases; Parkinson Disease; Phenylacetates; Phenylalanine; Spectrophotometry, Ultraviolet; Tyrosine | 1973 |
Amino acid levels in plasma, liver, and skeletal muscle during protein deprivation.
Topics: Alanine; Amino Acids; Animals; Asparagine; Aspartic Acid; Body Weight; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Male; Methionine; Muscles; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serine; Threonine; Time Factors; Tyrosine; Valine | 1973 |
Nutrient media for plant parasitic nematodes. V. Amino acid nutrition of Aphelenchoides rutgersi.
Topics: Alanine; Amino Acids; Aminobutyrates; Culture Media; Cysteine; Cystine; Glutamine; Histidine; Isoleucine; Leucine; Methionine; Mitosporic Fungi; Nematoda; Phenylalanine; Reproduction; Tyrosine | 1973 |
Relationship of protein metabolism to senescence of corn (Zea mays L.) stalk parenchyma, cob parenchyma and first developed leaf tissues.
Topics: Aging; Alanine; Amino Acids; Aspartic Acid; Carbon Isotopes; Cell Count; Chromatography; Dactinomycin; Glutamine; Leucine; Models, Biological; Ornithine; Phenylalanine; Plant Proteins; Plants; Ribonucleases; Ribosomes; RNA; RNA, Messenger; Threonine; Time Factors; Tyrosine | 1973 |
Urinary phenylalanine excretion in hyperphenylalaninemic children.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Humans; Infant; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
An allosteric alpha-glucan phosphorylase from banana fruits.
Topics: Adenosine Triphosphate; Allosteric Regulation; Ammonium Sulfate; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Freezing; Kinetics; Phenylalanine; Phosphorylases; Plants; Tryptophan; Tyrosine | 1973 |
Saturation of blood brain barrier transport of amino acids in phenylketonuria.
Topics: Amino Acids; Animals; Arginine; Blood-Brain Barrier; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Female; Histidine; Humans; Intellectual Disability; Isoleucine; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Phenylketonurias; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
The isolation and properties of a tyrosine-rich protein from wool: component 0.62.
Topics: Animals; Autoanalysis; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Electrophoresis, Starch Gel; Glycine; Hydrogen-Ion Concentration; Isoelectric Focusing; Keratins; Molecular Weight; Phenylalanine; Serine; Sheep; Solubility; Tryptophan; Tyrosine; Ultracentrifugation; Wool | 1973 |
The primary structure of a protein, component 0.62, rich in glycine and aromatic residues, obtained from wool keratin.
Topics: Amino Acid Sequence; Animals; Autoanalysis; Chromatography, Paper; Chymotrypsin; Electrophoresis, Paper; Glycine; Keratins; Peptides; Phenylalanine; Sheep; Thermolysin; Trypsin; Tryptophan; Tyrosine; Wool | 1973 |
Leaving group specificity in the chymotrypsin-catalyzed hydrolysis of peptides. A stereochemical interpretation.
Topics: Acetates; Acylation; Amides; Amino Acids; Aniline Compounds; Animals; Binding Sites; Carboxylic Acids; Catalysis; Cattle; Chymotrypsin; Furans; Hydrazines; Hydrolysis; Kinetics; Models, Chemical; Pancreas; Peptides; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Thermodynamics; Trypsin Inhibitors; Tryptophan; Tyrosine | 1973 |
Hydroxylation of phenylalanine by Pseudomonas sp.: measurement of an isotope effect following the NIH shift.
Topics: Carbon Isotopes; Energy Transfer; Hydroxylation; Kinetics; Phenylalanine; Pseudomonas; Structure-Activity Relationship; Tritium; Tyrosine | 1973 |
Stereoselective -labelling of aromatic amino-acids with deuterium and tritium.
Topics: Amines; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Cinnamates; Deuterium; Hydroxylation; Isotope Labeling; Methods; Phenylalanine; Tritium; Tyrosine | 1973 |
Anomalous phenylalanine loading responses in relation to cleft lip and cleft palate.
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Chromosomes, Human, 13-15; Cleft Lip; Cleft Palate; Female; Humans; Infant, Newborn; Karyotyping; Male; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Time Factors; Trisomy; Tyrosine | 1973 |
Neuronal lesions in the cerebellum following the administration of excess phenylalanine to neonatal rats.
Topics: Animals; Animals, Newborn; Axons; Cerebellum; Cytoplasm; Cytoplasmic Granules; Disease Models, Animal; Female; Humans; Liver; Myelin Sheath; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Purkinje Cells; Rats; Tyrosine | 1973 |
Amino acid requirement of the growing rabbits: an estimate of quantitative needs.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Cystine; Female; Glycine; Glycine max; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Plant Proteins; Rabbits; Species Specificity; Threonine; Tryptophan; Tyrosine; Valine | 1973 |
Rupture of rat liver lysosomes mediated by L-amino acid esters.
Topics: Acid Phosphatase; Alanine; Amino Acids; Animals; Cell Fractionation; Electrophoresis, Paper; Esters; Glycine; Hydrogen-Ion Concentration; Leucine; Liver; Lysosomes; Male; Methionine; Osmolar Concentration; Phenylalanine; Rats; Spectrophotometry; Stereoisomerism; Time Factors; Tyrosine | 1973 |
Changes in the tertiary structure of alpha-chymotrypsin with change in pH: p4 4.2-6.7.
Topics: Alanine; Amino Acid Sequence; Aspartic Acid; Binding Sites; Chymotrypsin; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Methionine; Models, Structural; Phenylalanine; Protein Binding; Protein Conformation; Serine; Tyrosine; Uranium; X-Ray Diffraction | 1973 |
Chromatography of plant aminoacyl-tRNA synthetases on omega-aminoalkyl sepharose columns.
Topics: Amines; Amino Acyl-tRNA Synthetases; Butylamines; Carbon Radioisotopes; Chromatography, Affinity; Ethylamines; Hydrogen-Ion Concentration; Molecular Weight; Phenylalanine; Plants; Polysaccharides; Seeds; Serine; Spectrophotometry, Ultraviolet; Tritium; Tryptophan; Tyrosine; Valine | 1973 |
Synthesis of essential amino acids from their alpha-keto analogues by perfused rat liver and muscle.
Topics: Acetoacetates; Amino Acids, Essential; Animals; Butyrates; Caproates; Female; Glucose; Glutamates; Glutamine; Hydroxybutyrates; Keto Acids; Leucine; Liver; Methionine; Muscles; Perfusion; Phenylalanine; Phenylpyruvic Acids; Rats; Tyrosine; Urea; Valine | 1973 |
Folic acid administration to children with hyperphenylalaninaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Female; Folic Acid; Humans; Male; Phenylalanine; Spectrometry, Fluorescence; Tyrosine | 1973 |
Uncorporation of phenylalanine as a single unit into rat brain protein: reciprocal inhibition by phenylalanine and tyrosine of their respective incorporations.
Topics: Adenosine Triphosphate; Aging; Animals; Asparagine; Brain; Carbon Radioisotopes; Glutamates; Glutamine; Histidine; In Vitro Techniques; Kidney; Kinetics; Liver; Magnesium; Methionine; Nerve Tissue Proteins; Phenylalanine; Potassium; Rats; Thyroid Gland; Tritium; Tryptophan; Tyrosine | 1973 |
Effect of light on enzymes of phenylpropanoid metabolism and hispidin biosynthesis in Polyporus hispidus.
Topics: Ammonia-Lyases; Basidiomycota; Carbon Radioisotopes; Cinnamates; Coumarins; Light; Phenylalanine; Pyrans; Pyrones; Spectrophotometry, Ultraviolet; Styrenes; Tyrosine | 1973 |
The uptake and efflux of L-phenylalanine and L-tyrosine from rat brain cerebral cortex slices.
Topics: Animals; Biological Transport, Active; Cerebral Cortex; In Vitro Techniques; Kinetics; Phenylalanine; Potassium; Rats; Sodium; Tryptophan; Tyrosine; Water | 1973 |
Classic phenylketonuria: heterozygote detection during pregnancy.
Topics: Adolescent; Adult; Analysis of Variance; Female; Genetic Counseling; Genotype; Heterozygote; Homozygote; Humans; Infant, Newborn; Male; Mathematics; Microchemistry; Pedigree; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1973 |
Anomalous pH dependence of kcat-KM in enzyme reactions. Rate constants for the association of chymotrypsin with substrates.
Topics: Acetates; Binding Sites; Chymotrypsin; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitrophenols; Oscillometry; Phenylalanine; Protein Binding; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1973 |
The biosynthetic origin of chlorflavonin, a flavonoid antibiotic from Aspergillus candidus.
Topics: Acetates; Anti-Bacterial Agents; Aspergillus; Carbon Radioisotopes; Chlorine; Chlorobenzenes; Cinnamates; Coumarins; Flavonoids; Glucose; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methionine; Phenylalanine; Sodium; Tyrosine | 1973 |
Immune-response genes linked to the major histocompatibility system in the rat.
Topics: Alanine; Animals; Antibody Formation; Antigens; Glutamates; Histidine; Histocompatibility Antigens; Immunogenetics; Iodine Radioisotopes; Lysine; Peptides; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1973 |
Heterozygous carriers in the relatives of a case of phenylketonuria.
Topics: Computers; Female; Heterozygote; Humans; Male; Mathematics; Pedigree; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
Screening for hyperaminoacidemias in newborns by thin-layer chromatography on DEAE-cellulose.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Belgium; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leucine; Mass Screening; Methods; Phenylalanine; Tyrosine; Valine | 1973 |
The effect of a phenylalanine-tyrosine low diet on the growth and morphology of transplantable malignant melanomas of the Syrian golden hamster (Mesocricetus auratus).
Topics: Animals; Cell Transformation, Neoplastic; Copper; Cricetinae; Diet; Hair; Melanins; Melanocytes; Melanoma; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Pigmentation Disorders; Protein Deficiency; Skin; Skin Neoplasms; Transplantation, Homologous; Tyrosine | 1973 |
The factor analytic, logarithmic and optimum solutions in separating heterozygous carriers and normal control subjects in phenylketonuria.
Topics: Factor Analysis, Statistical; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
Ion-exchange thin-layer chromatographic screening test for phenylketonuria and other aminoacidaemias.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, Ion Exchange; Chromatography, Thin Layer; Histidine; Humans; Infant; Lysine; Male; Mass Screening; Methods; Phenylalanine; Phenylketonurias; Tyrosine | 1973 |
[Diagnosis and therapy of the secondary disease: dermatology].
Topics: Candidiasis; Diabetes Complications; Female; Herpes Zoster; Humans; Liver Diseases; Malabsorption Syndromes; Male; Parathyroid Diseases; Phenylalanine; Pigmentation Disorders; Skin Diseases; Skin Manifestations; Tryptophan; Tyrosine; Vitamin B 12 Deficiency | 1973 |
Proteolytic enzymes in experimental rat pancreatitis.
Topics: Acute Disease; Amylases; Animals; Caseins; Hydrolysis; Male; Nitro Compounds; Pancreas; Pancreatitis; Peptide Hydrolases; Phenylalanine; Rats; Time Factors; Trypsin; Trypsin Inhibitors; Tyrosine | 1973 |
Supplemental effect of lysine on growth depression of rats fed wheat gluten diets containing excessive amount of some individual amino acids.
Topics: Amino Acids; Animals; Arginase; Arginine; Depression, Chemical; Diet; Glutens; Growth; Liver; Lysine; Male; Methionine; Phenylalanine; Rats; Triticum; Tryptophan; Tyrosine | 1973 |
The role of phenylalanine in differentiating amphibian melanocytes.
Topics: Ambystoma; Animals; Autoradiography; Cell Differentiation; Dihydroxyphenylalanine; Ganglia; Lactates; Leucine; Melanins; Melanocytes; Nervous System; Phenylalanine; Protein Biosynthesis; Puromycin; Tritium; Tyrosine | 1973 |
Tyrosinosis.
Topics: Acute Disease; Amino Acid Metabolism, Inborn Errors; Chromatography, Paper; Chronic Disease; Humans; Infant; Phenylalanine; Time Factors; Tyrosine | 1973 |
[Characteristics of the electronic structure of catecholamines and their precursors].
Topics: Catecholamines; Computers; Dihydroxyphenylalanine; Dopamine; Electrons; Epinephrine; Norepinephrine; Phenylalanine; Tyrosine | 1973 |
Stereochemistry of ammonia elimination from L-tyrosine with L-phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Binding Sites; Chymotrypsin; Deuterium; Magnetic Resonance Spectroscopy; Mitosporic Fungi; Optical Rotation; Phenylalanine; Stereoisomerism; Tritium; Tyrosine | 1973 |
Specific interaction of peptides with nucleic acids. Evidence for a "selective bookmark" recognition hypothesis.
Topics: Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Chromatin; Circular Dichroism; Dialysis; Dipeptides; DNA; DNA, Bacterial; Lysine; Magnetic Resonance Spectroscopy; Male; Models, Chemical; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligopeptides; Peptides; Phenylalanine; Salmon; Spermatozoa; Temperature; Tryptophan; Tyrosine; Viscosity | 1973 |
Insulin self-association. Spectrum changes and thermodynamics.
Topics: Animals; Cattle; Circular Dichroism; Hydrogen-Ion Concentration; Insulin; Macromolecular Substances; Mathematics; Osmolar Concentration; Phenylalanine; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Tyrosine; Zinc | 1973 |
Complex formation between bovine neurophysin-I and oxytocin, vasopressin, and tripeptide analogs of their NH2-terminal region. Absorbance and circular dichroism difference spectroscopic studies.
Topics: Amines; Amino Acid Sequence; Animals; Binding Sites; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; Cystine; Evaluation Studies as Topic; Isoleucine; Lysine; Methods; Models, Chemical; Neurophysins; Oligopeptides; Oxytocin; Phenylalanine; Protein Binding; Protein Conformation; Proteins; Spectrophotometry, Ultraviolet; Tyrosine; Vasopressins | 1973 |
[Effect of the set of amino acids contained in casein, extracted soy bean meal, horse beans and wheat gluten on the content of leucine, isoleucine, valine, phenylalanine, tyrosine, glutamic acid, aspartic acid, alanine, glycine and proline in the deprotei
Topics: Alanine; Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aspartic Acid; Caseins; Chickens; Female; Glutamates; Glutens; Glycine; Glycine max; Isoleucine; Leucine; Phenylalanine; Plant Proteins; Proline; Triticum; Tyrosine; Valine | 1973 |
Further studies on the circular dichroism of carboxypeptidase A (ANSON). Reduced-monoalkylated carboxypeptidase A, and carboxypeptidase Aalpha, Abeta, and Agamma.
Topics: Acetamides; Alkylation; Animals; Benzoates; Carboxypeptidases; Cattle; Chromatography, DEAE-Cellulose; Circular Dichroism; Disulfides; Hydrogen-Ion Concentration; Iodoacetates; Kinetics; Mercuribenzoates; Oxidation-Reduction; Pancreas; Phenylalanine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1973 |
UDP-galactose: glycoprotein galactosyl transferase and UDP-N-acetylgalactosamine: protein N-acetylgalactosaminyl transferase activities of human cerebrospinal fluid.
Topics: Animals; Carbon Radioisotopes; Chromatography, Paper; Colostrum; Galactosamine; Galactose; Glycoproteins; Hexosyltransferases; Humans; Hydrolysis; Kinetics; Lactates; Milk; Mucins; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Structure-Activity Relationship; Tyrosine | 1973 |
[Disorders of the liver phenylalanine hydroxylase system in viral hepatitis].
Topics: Adolescent; Adult; Aged; Epinephrine; Hepatitis A; Humans; Liver; Middle Aged; Norepinephrine; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Tyrosine | 1973 |
Primary cultures of dissociated sympathetic neurons. II. Initial studies on catecholamine metabolism.
Topics: Animals; Ascorbic Acid; Catecholamines; Cells, Cultured; Dopamine; Ganglia, Autonomic; Kinetics; Neurons; Norepinephrine; Phenylalanine; Pteridines; Rats; Time Factors; Tyrosine | 1973 |
Evidence of an essential histidine residue in thermolysin.
Topics: Anhydrides; Benzyl Compounds; Binding Sites; Binding, Competitive; Drug Stability; Enzyme Activation; Ethyl Ethers; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; Phenylalanine; Spectrophotometry, Ultraviolet; Thermolysin; Tyrosine | 1974 |
The development of children with transient neonatal tyrosinemia.
Topics: Central Nervous System; Child; Child Development; Child, Preschool; Growth; Humans; Infant; Infant, Newborn; Intelligence; Intelligence Tests; Neurologic Examination; Phenylalanine; Prospective Studies; Psychological Tests; Tyrosine | 1974 |
The use of biochemical data in screening for mutant alleles and in genetic counselling.
Topics: Alleles; Genetic Counseling; Heterozygote; Hexosaminidases; Hot Temperature; Humans; Lipidoses; Molecular Biology; Mutation; Phenylalanine; Phenylketonurias; Probability; Tyrosine | 1974 |
Inhibition of Azotobacter vinelandii ribonucleic acid polymerase by glutamyl, tyrosyl copolymers.
Topics: Adenine Nucleotides; Aspartic Acid; Azotobacter; DNA-Directed RNA Polymerases; Glutamates; Leucine; Magnesium Sulfate; Osmolar Concentration; Peptides; Phenylalanine; Phosphorus Radioisotopes; Potassium Chloride; Protein Binding; Structure-Activity Relationship; Templates, Genetic; Thymine Nucleotides; Tritium; Tryptophan; Tyrosine; Ultracentrifugation | 1974 |
Dopamine and serotonin metabolism in hepatic encephalopathy.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Brain; Dopamine; Fatty Acids, Nonesterified; Female; Halothane; Hepatic Encephalopathy; Hepatitis A; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methionine; Middle Aged; Phenylalanine; Serotonin; Tryptophan; Tyrosine | 1974 |
Proteins lacking certain amino acids.
Topics: Arginine; Aspartic Acid; Cysteine; Glutamates; Histidine; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Proteins; Tryptophan; Tyrosine; Valine | 1974 |
Fluorometric measurement of tyrosine in serum and plasma.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Autoanalysis; Blood Proteins; Child; Child, Preschool; Drug Stability; Evaluation Studies as Topic; Humans; Infant; Infant, Newborn; Infant, Premature; Methods; Phenylalanine; Phenylketonurias; Spectrometry, Fluorescence; Temperature; Time Factors; Tyrosine | 1974 |
[Prolonged phenylalanine load].
Topics: Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Tyrosine | 1974 |
[Does phenylalanine load disclose genetic variants?].
Topics: Female; Genotype; Humans; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1974 |
[Centralized PKU treatment in Denmark].
Topics: Child; Child, Preschool; Denmark; Diet Therapy; Hospitals, Special; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Psychological Tests; Tyrosine | 1974 |
Biosynthesis of chloramphenicol in Streptomyces species 3022a. Isotope incorporation experiments with (G-14C) chorismic, (G-14C) prephenic, and (G-14C, 6-3H) shikimic acids.
Topics: Aspartic Acid; Carbon Radioisotopes; Cell Membrane; Chemical Phenomena; Chemistry; Chloramphenicol; Chromatography, Paper; Chromatography, Thin Layer; Cyclohexanecarboxylic Acids; Glutamates; Phenylalanine; Phenylpyruvic Acids; Pyruvates; Shikimic Acid; Spectrophotometry; Streptomyces; Tritium; Tyrosine | 1974 |
Isolation and properties of a new glutamine transaminase from rat kidney.
Topics: Amidohydrolases; Animals; Brain; Glutamine; Glutarates; Glyoxylates; Isoenzymes; Keto Acids; Kidney; Kinetics; Liver; Male; Methionine; Mitochondria; Myocardium; Organ Specificity; Phenylalanine; Phenylpyruvic Acids; Rats; Solubility; Structure-Activity Relationship; Transaminases; Tyrosine | 1974 |
Intracellular free amino acid concentration in human muscle tissue.
Topics: Adult; Alanine; Amino Acids; Arginine; Asparagine; Biopsy, Needle; Body Water; Chlorides; Citrulline; Extracellular Space; Female; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Lipid Metabolism; Male; Muscles; Ornithine; Phenylalanine; Proline; Serine; Taurine; Tyrosine; Valine | 1974 |
Histochemical studies of nonenzymatic reduction of nitro-BT by catecholamines and their precursors in extracellular model systems.
Topics: Animals; Basal Ganglia; Catecholamines; Cats; Cerebral Cortex; Cystine; Dihydroxyphenylalanine; Epinephrine; Histocytochemistry; Homocystine; Norepinephrine; Oxidation-Reduction; Phenylalanine; Rats; Tetrazolium Salts; Tyrosine | 1974 |
Growth of human diploid fibroblasts in media with different amino acid composition.
Topics: Amino Acids; Cell Adhesion; Cell Division; Culture Media; Cystine; Fibroblasts; Glutamine; Histidine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; Methionine; Phenylalanine; Pyruvates; Stimulation, Chemical; Threonine; Tyrosine; Valine | 1974 |
On the importance of decarboxylation in the metabolism of phenylalanine, tyrosine, and tryptophan.
Topics: Administration, Oral; Amino Acids; Animals; Benserazide; Carbon Radioisotopes; Carboxy-Lyases; Dopa Decarboxylase; Kidney; Leucine; Liver; Male; Phenylalanine; Rats; Time Factors; Tryptophan; Tyramine; Tyrosine; Valine | 1974 |
Changes in the concentration of free amino acids in the haemolymph of Rhodnius prolixus during the fifth instar.
Topics: Amino Acids; Animals; Hemolymph; Histidine; Insecta; Leucine; Metamorphosis, Biological; Phenylalanine; Proline; Time Factors; Tyrosine | 1974 |
Increased conversion of a phenylalanine load to tyrosine in tetraiodoglucagon-treated rats.
Topics: Animals; Glucagon; Liver; Male; Phenylalanine; Rats; Spectrometry, Fluorescence; Time Factors; Tyrosine | 1974 |
Neonatal screening for phenylketonuria. IV. Factors influencing the occurrence of false positives.
Topics: Age Factors; Birth Weight; False Positive Reactions; Humans; Infant, Newborn; Ontario; Phenylalanine; Phenylketonurias; Public Health Administration; Quebec; Racial Groups; Tyrosine; United States; White People | 1974 |
Ruminal biosynthesis of aromatic amino acids from arylacetic acids, glucose, shikimic acid and phenol.
Topics: Amino Acids; Animals; Bacteria; Bacterial Proteins; Carbon Radioisotopes; Female; Glucose; Indoleacetic Acids; Male; Phenols; Phenylacetates; Phenylalanine; Rumen; Shikimic Acid; Tryptophan; Tyrosine | 1974 |
Quantitative analysis of phenylalanine metabolites in urine to detect heterozygotes of phenylketonuria.
Topics: Chromatography, Gas; Heterozygote; Humans; Mandelic Acids; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Time Factors; Tyrosine | 1974 |
Characterization and mating reactions of clinical isolates of Trychophyton mentagrophytes and T. rubrum which produce a diffusible brownish pigment.
Topics: Agar; Ascomycota; Asparagine; Conjugation, Genetic; Culture Media; Hair; Humans; Keratins; Phenylalanine; Pigments, Biological; Quinic Acid; Shikimic Acid; Stereoisomerism; Tinea; Trichophyton; Tyrosine; Urease | 1974 |
Letter: Frequency of some metabolic disorders in Poland.
Topics: Biological Assay; Galactosemias; Histidine; Humans; Infant, Newborn; Mass Screening; Phenylalanine; Phenylketonurias; Poland; Tyrosine | 1974 |
Lipid metabolism in liver and brain in acute hyperphenylalaninemia in rats of different ages. Correlation with tissue phenylalanine and tyrosine levels.
Topics: Acetates; Aging; Animals; Animals, Newborn; Brain; Carbon Radioisotopes; Cholesterol; Chromatography, Thin Layer; Female; Glycolipids; Lipid Metabolism; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phospholipids; Rats; Time Factors; Tyrosine | 1974 |
Aromatic amino acid-lysine copolymers. Conformation and specificity of nucleotide interaction.
Topics: Amino Acids; Binding Sites; Circular Dichroism; Dialysis; Lysine; Methanol; Molecular Conformation; Molecular Weight; Nucleotides; Phenylalanine; Polymers; Solutions; Spectrophotometry; Tryptophan; Tyrosine; Water | 1974 |
Studies concerning the biochemical genetics of activity and feedback inhibition mutants of Schizosaccharomyces pombe 3-deoxy-D-arabino-neptulosomate-7-phosphate synthase.
Topics: Aldehyde-Lyases; Allosteric Regulation; Ascomycota; Chromatography, Gel; Crosses, Genetic; Diploidy; Genetic Complementation Test; Genetic Linkage; Hydrogen-Ion Concentration; Mutation; Nitrosoguanidines; Phenylalanine; Spectrophotometry; Spores, Fungal; Sugar Phosphates; Tryptophan; Tyrosine | 1974 |
[Attempted physiopathologic interpretation of phenylketonuria (PKU)].
Topics: Brain; Citric Acid Cycle; Humans; Hydroxylation; Mitochondria; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1974 |
Studies on orchidaceae alkaloids. XXXIX. Isolation of (minus)-cryptostyline I, II, 3 and two quaternary salts from cryptostylis erythroglossa hayata. Biosynthetic studies of (minus)-cryptostyline I.
Topics: Alkaloids; Benzaldehydes; Benzoates; Bromides; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chlorides; Chromatography, Thin Layer; Dopamine; Isoquinolines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methods; Phenethylamines; Phenylalanine; Picrates; Plants, Medicinal; Spectrophotometry, Ultraviolet; Styrenes; Tritium; Tyramine; Tyrosine | 1974 |
The mean geometry of the peptide unit from crystal structure data.
Topics: Acetamides; Alanine; Crystallography; Glutathione; Glycine; Leucine; Models, Structural; Molecular Conformation; Oligopeptides; Phenylalanine; Proline; Protein Conformation; Tyrosine; X-Ray Diffraction | 1974 |
Tyrosine and phenylalanine concentrations in haemolymph and tissues of the American cockroach, Periplaneta americana, during metamorphosis.
Topics: Animals; Cockroaches; Hemolymph; Male; Metamorphosis, Biological; Phenylalanine; Tyrosine | 1974 |
Porcine intestinal calcium-binding protein. Molecular properties and the effect of binding calcium ions.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Calcium; Carboxypeptidases; Circular Dichroism; Dansyl Compounds; Intestinal Mucosa; Isoelectric Focusing; Molecular Weight; Phenylalanine; Protein Binding; Proteins; Receptors, Drug; Spectrophotometry, Ultraviolet; Swine; Tyrosine; Ultracentrifugation | 1974 |
The enzyme-enzyme complex of transaminase and glutamate dehydrogenase.
Topics: Amino Acids; Animals; Aspartate Aminotransferases; Aspartic Acid; Cattle; Chromatography, Gel; Cytoplasm; Glutamate Dehydrogenase; Glutamates; Ketoglutaric Acids; Kinetics; Macromolecular Substances; Mitochondria, Liver; Multienzyme Complexes; Myocardium; Organophosphorus Compounds; Phenylalanine; Phenylhydrazines; Phenylpyruvic Acids; Pyridoxal Phosphate; Pyridoxamine; Swine; Tyrosine | 1974 |
Arterial mesenchyme and arteriosclerosis. Enzymic vs non-enzymic factors in the deterioration of connective tissue.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Blood Platelets; Cattle; Child; Collagen; Connective Tissue; Culture Techniques; Elastic Tissue; Elastin; Female; Fluorescence; Humans; Leukocytes; Male; Middle Aged; Pancreatic Elastase; Phenylalanine; Pregnancy; Proteins; Solubility; Tyrosine; Ultraviolet Rays; X-Ray Diffraction | 1974 |
Intrinsic enzymatic activity of bovine procarboxypeptidase A S5.
Topics: Acetates; Amino Acid Sequence; Animals; Benzene Derivatives; Carbon Radioisotopes; Carboxypeptidases; Catalysis; Cattle; Chromatography, DEAE-Cellulose; Enzyme Activation; Enzyme Precursors; Glutamates; Hydrogen-Ion Concentration; Kinetics; Methane; Nitro Compounds; Oxazoles; Phenanthrolines; Phenylalanine; Protein Conformation; Sulfonic Acids; Thermolysin; Tyrosine | 1974 |
The pH dependence of the pepsin-catalyzed hydrolysis of N-acetyl-L-phenylalanyl-L-3,5-dibromotyrosine.
Topics: Hydrogen-Ion Concentration; Kinetics; Pepsin A; Phenylalanine; Tyrosine | 1967 |
The effect of 5-fluorouracil and 6-thioguanine incorporation on the amino acid acceptor activity of Escherichia coli tRNA.
Topics: Alanine; Amino Acids; Carbon Isotopes; Centrifugation, Density Gradient; Escherichia coli; Fluorouracil; Glutamates; Leucine; Lysine; Methionine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Thioguanine; Tyrosine; Valine | 1967 |
Purification of methionine-, valine-, phenylalanine- and tyrosine-specific tRNA from Escherichia coli.
Topics: Chromatography; Escherichia coli; Ligases; Magnesium; Methionine; Nucleotides; Phenylalanine; Protein Denaturation; RNA, Bacterial; RNA, Transfer; Temperature; Tyrosine; Valine | 1967 |
The effect of p-fluorophenylalanine on nucleic acid biosynthesis and cell division in Escherichia coli.
Topics: Carbon Isotopes; Cell Division; DNA Replication; DNA, Bacterial; Escherichia coli; Fluorine; Isocitrate Dehydrogenase; Phenylalanine; Puromycin; RNA Nucleotidyltransferases; RNA, Bacterial; Spectrophotometry; Thymine; Tyrosine | 1967 |
Chromatography of 3-deoxy-D-arabinoheptulosonic acid-7-phosphate synthetase (trp) on diethylaminoethyl cellulose: a correction.
Topics: Chromatography; Escherichia coli; Ligases; Mutation; Phenylalanine; Tryptophan; Tyrosine | 1967 |
Epistasis between deletion mutations in the tryptophan region and mutations affecting the general aromatic pathway in Escherichia coli K-12.
Topics: Amino Acids; Aminobenzoates; Benzoates; Chromosome Mapping; Coliphages; Escherichia coli; Genes; Genetic Code; Indoles; Mutation; Phenylalanine; Shikimic Acid; Transduction, Genetic; Tryptophan; Tyrosine | 1967 |
Hydroxymethylation of the benzene ring. 3. Synthesis of the D- and L-isomers of p-hydroxymethylphenylalanine and the biochemical properties of the L-isomer.
Topics: Acetates; Amides; Amines; Benzene Derivatives; Escherichia coli; Glutamates; Infrared Rays; Magnetic Resonance Spectroscopy; Malonates; Methanol; Methods; Methylation; Optical Rotatory Dispersion; Phenylalanine; Serine; Spectrum Analysis; Tyrosine; Ultraviolet Rays | 1967 |
Comparative regulation of isoenzymic 3-deoxy-D-arabino-heptulosonate 7-phosphate synthetases in microorganisms.
Topics: Bacteria; Enzyme Repression; Escherichia; Escherichia coli; Isoenzymes; Ligases; Neurospora; Phenylalanine; Pseudomonas; Salmonella typhimurium; Tryptophan; Tyrosine | 1968 |
Specific hybridization of amino acid-specific transfer RNA to DNA in Escherichia coli.
Topics: DNA, Bacterial; Escherichia coli; Hybridization, Genetic; Kinetics; Methionine; Nucleic Acid Denaturation; Phenylalanine; Phosphorus Isotopes; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Templates, Genetic; Tyrosine; Valine | 1968 |
Nutrition of Myxococcus xanthus FBa and some of its auxotrophic mutants.
Topics: Amino Acids; Bacteria; Carbon Isotopes; Deoxyribonucleases; Glucose; Mutation; Myxomycetes; Phenylalanine; Purines; Pyrimidines; Ribonucleases; Ribose; Salmonella typhimurium; Tyrosine | 1968 |
Comparative studies on specific and nonspecific binding of transfer ribonucleic acid to ribosomes.
Topics: Carbon Isotopes; Escherichia coli; Leucine; Lysine; Magnesium; Methionine; Phenylalanine; Ribosomes; RNA, Messenger; RNA, Transfer; Serine; Tetracycline; Tritium; Trypsin; Tyrosine; Uracil Nucleotides | 1968 |
The nature of the binding of inhibitors to pepsin and the kinetics of inhibited peptic hydrolysis of N-acetyl-L-phenylalanyl-L-tyrosine.
Topics: Binding Sites; Chemical Phenomena; Chemistry, Physical; Kinetics; Models, Biological; Pepsin A; Peptides; Phenylalanine; Tyrosine | 1968 |
Hydroxymethylation of the benzene ring. IV. p-Hydroxymethyl-L-phenylalanine, a naturally occuring amino acid in Escherichia coli: identification and biochemical properties.
Topics: Autoanalysis; Chromatography, Ion Exchange; Escherichia coli; Phenylalanine; Tritium; Tyrosine | 1968 |
Inhibition of the pepsin catalyzed hydrolysis of diphenyl sulfite by N-acetyl-L-phenyl-alanine, 3,5-dibromo-L-tryosine and N-acetyl-L-phenylalanyl-3,5-dibromo-L-tyrosine.
Topics: Kinetics; Pepsin A; Peptides; Phenols; Phenylalanine; Sulfites; Tyrosine | 1968 |
Amino acid transport systems in Escherichia coli K-12.
Topics: Alanine; Amino Acids; Azides; Biological Transport; Calcium; Carbon Isotopes; Escherichia coli; Glycine; Hydrogen-Ion Concentration; Kinetics; Leucine; Methionine; Phenylalanine; Serine; Sodium; Temperature; Tryptophan; Tyrosine; Valine | 1968 |
Chromatographic alterations in transfer RNA's accompanying speciation, differentiation and tumor formation.
Topics: Adenoviridae; Animals; Biological Evolution; Brain; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cattle; Chickens; Chromatography; Cricetinae; Culture Techniques; Embryo, Mammalian; Embryo, Nonmammalian; Escherichia coli; Fibroblasts; Glycine; HeLa Cells; Humans; Kidney; Leucine; Liver; Mice; Muscles; Organ Specificity; Phenylalanine; Rabbits; RNA, Neoplasm; RNA, Transfer; Saccharomyces; Serine; Species Specificity; Tritium; Tyrosine | 1968 |
Regulation of aromatic amino acid biosynthesis Escherichia coli K12.
Topics: Enzyme Repression; Escherichia coli; Genes, Regulator; Heptoses; Hydro-Lyases; Isomerases; Ligases; Phenylalanine; Tryptophan; Tyrosine | 1968 |
Effect of amino acids and purine bases on thiamine synthesis by Escherichia coli.
Topics: Adenine; Amino Acids; Aspartic Acid; Culture Media; Cystine; Cytosine; Escherichia coli; Glutamates; Glycine; Guanine; Histidine; Hypoxanthines; Inositol; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Purines; Serine; Thiamine; Thiazoles; Threonine; Thymine; Tyrosine; Uracil; Valine | 1968 |
Pathways of biosynthesis of aromatic amino acids and vitamins and their control in microorganisms.
Topics: Aminobenzoates; Bacteria; Benzoates; Chromosome Mapping; Enterobacter; Enzyme Repression; Escherichia coli; Feedback; Isoenzymes; Ligases; Phenylalanine; Tryptophan; Tyrosine; Ubiquinone; Vitamin K | 1968 |
Suppressor selectrion for amino acid replacements expected on the basis of the genetic code.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bacterial Proteins; Escherichia coli; Genes; Genetic Code; Genetics, Microbial; Glutamates; Glycine; Histidine; Hydro-Lyases; Isoleucine; Leucine; Lysine; Methionine; Mutation; Nucleotides; Phenylalanine; RNA, Messenger; Serine; Suppression, Genetic; Threonine; Tyrosine; Valine | 1967 |
Aromatic amino acid biosynthesis in Trichophyton rubrum. II. Failure to detect endogenous shikimic acid and related substances.
Topics: Benzoates; Biological Assay; Catechols; Escherichia coli; Phenylalanine; Quinic Acid; Shikimic Acid; Trichophyton; Tyrosine | 1969 |
Fidelity of genetic code translation in a rat liver ribosomal system.
Topics: Animals; Carbon Isotopes; Escherichia coli; Genetic Code; Isoleucine; Liver; Male; Neomycin; Phenylalanine; Rats; Ribosomes; Serine; Streptomycin; Tyrosine | 1969 |
Formation of aminoacyl-sRNA synthetases during growth phases of Escherichia coli.
Topics: Adenosine Triphosphate; Escherichia coli; Isoleucine; Leucine; Ligases; Methionine; Phenylalanine; Tryptophan; Tyrosine; Ultrasonics; Valine | 1969 |
The pH-dependence of the binding of competitive inhibitors to pepsin.
Topics: Amides; Binding Sites; Dipeptides; Glycine; Hydrogen-Ion Concentration; Lactates; Pepsin A; Phenylalanine; Tyrosine | 1969 |
The rate-determining step in pepsin-catalysed reactions, and evidence against an acyl-enzyme intermediate.
Topics: Carbon Isotopes; Dipeptides; Esters; Glycine; Kinetics; Methanol; Pepsin A; Peptides; Phenylalanine; Tyrosine | 1969 |
[Mass screening of phenylketonuria. Report on a screening center (October 1967-December 1968)].
Topics: Adolescent; Adult; Amino Acids; Bacteriological Techniques; Child; Child, Preschool; Chromatography, Paper; Fluorometry; France; Homocystinuria; Humans; Infant; Infant, Newborn; Mass Screening; Methionine; Phenylalanine; Phenylketonurias; Sampling Studies; Tyrosine | 1969 |
Altered chromatographic properties of tRNA from chloramphenicol-treated Escherichia coli.
Topics: Carbon Isotopes; Chloramphenicol; Chromatography; Escherichia coli; Leucine; Ligases; Methylation; Phenylalanine; RNA, Bacterial; RNA, Transfer; Tritium; Tyrosine | 1969 |
The side-chain specificity of pepsin.
Topics: Alanine; Chromatography, Thin Layer; Indicators and Reagents; Kinetics; Leucine; Methionine; Pepsin A; Peptides; Phenylalanine; Tyrosine; Valine | 1969 |
The pH dependence of the dephosphorylated pepsin-catalyzed hydrolysis of N-acetyl-L-phenylalanyl-L-tyrosine methyl ester.
Topics: Acid Phosphatase; Animals; Catalysis; Chemical Phenomena; Chemistry; Dipeptides; Esters; Hydrogen-Ion Concentration; Kinetics; Pepsin A; Phenylalanine; Phosphates; Swine; Tyrosine | 1970 |
Regulation of the Escherichia coli tryptophan operon by early reactions in the aromatic pathway.
Topics: Aldehyde-Lyases; Amino Acids; Chromatography, DEAE-Cellulose; Culture Media; Enzyme Repression; Escherichia coli; Genetics, Microbial; Heptoses; Molecular Biology; Mutation; Operon; ortho-Aminobenzoates; Phenylalanine; Transaminases; Tryptophan; Tyrosine | 1970 |
A simple procedure for fractionation of transfer RNA.
Topics: Albumins; Cellulose; Chromatography; Escherichia coli; Filtration; Histidine; Leucine; Lysine; Membranes, Artificial; Methionine; Methods; Phenylalanine; Proline; RNA, Bacterial; RNA, Transfer; Time Factors; Tritium; Tyrosine | 1970 |
The transfer RNA binding site of the 30 S ribosome and the site of tetracycline inhibition.
Topics: Alkanes; Bacterial Proteins; Binding Sites; Carbon Isotopes; Chromosomes, Bacterial; Depression, Chemical; Drug Resistance, Microbial; Escherichia coli; Kinetics; Models, Biological; Models, Structural; Mutation; Phenylalanine; Polynucleotides; Ribosomes; RNA, Bacterial; RNA, Messenger; RNA, Transfer; Tetracycline; Time Factors; Transduction, Genetic; Tyrosine | 1969 |
Effects of infection on selected clinical and biochemical parameters in dogs.
Topics: Amino Acids; Animals; Blood Cell Count; Blood Proteins; Body Temperature; Body Weight; Diet; Dogs; Kidney; Liver; Male; Organ Size; Phenylalanine; Salmonella Infections; Salmonella typhimurium; Spleen; Tyrosine | 1970 |
Identification of sulfur-containing bases in transfer ribonucleic acids by phosphorescence spectroscopy.
Topics: Escherichia coli; Luminescent Measurements; Magnesium; Nucleosides; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Thiouracil; Tyrosine; Valine | 1970 |
Formation of aromatic amino acid pools in Escherichia coli K-12.
Topics: Amino Acids; Biological Transport; Carbon Isotopes; Chromosome Mapping; Dinitrophenols; Escherichia coli; Glucose; Molecular Biology; Mutation; Phenylalanine; Transduction, Genetic; Tryptophan; Tyrosine | 1970 |
Inhibition by phenylalanine of thiazole biosynthesis in Escherichia coli.
Topics: Depression, Chemical; Escherichia coli; Genetics, Microbial; Mutation; Phenylalanine; Shikimic Acid; Thiamine; Thiazoles; Tryptophan; Tyrosine | 1970 |
Aromatic amino acid biosynthesis in Trichophyton rubrum. 3. Exogenous studies: absence of the shikimic acid pathway.
Topics: Biological Assay; Carbon Isotopes; Cell Wall; Culture Media; Cytoplasm; Escherichia coli; Glucose; Oxygen Consumption; Permeability; Phenylalanine; Pigments, Biological; Quinic Acid; Shikimic Acid; Trichophyton; Tyrosine | 1970 |
Chemical modifications of transfer RNA species. Desulfurization with Raney nickel.
Topics: Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Escherichia coli; Nickel; Nucleosides; Phenylalanine; Plant Growth Regulators; RNA, Bacterial; RNA, Transfer; Serine; Spectrum Analysis; Sulfur; Tyrosine | 1971 |
[Metabolic products of microorganisms. 88. Effect of L-2,5-dihydrophenylalanine--a phenylalanine antagonist].
Topics: Amino Acids; Dihydroxyphenylalanine; Escherichia coli; Mutation; Phenylalanine; Tyrosine | 1971 |
The primary structure of transfer ribonucleic acid.
Topics: Alanine; Aspartic Acid; Cryptococcus; Escherichia coli; Genetic Code; Isoleucine; Leucine; Methionine; Methylation; Nucleotides; Phenylalanine; RNA, Transfer; Saccharomyces; Serine; Tryptophan; Tyrosine; Valine | 1971 |
2'-O-Methyl polynucleotides as templates for cell-free amino acid incorporation.
Topics: Adenine Nucleotides; Amino Acids; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Cytosine Nucleotides; Escherichia coli; Ethers; Genetic Code; Isoleucine; Kinetics; Leucine; Methanol; Methylation; Molecular Biology; Neomycin; Phenylalanine; Polynucleotides; Proline; Protein Biosynthesis; Ribonucleotides; RNA, Bacterial; Serine; Templates, Genetic; Tyrosine; Uracil Nucleotides | 1971 |
Uptake of nonmetabolites by brain slices.
Topics: Amines; Brain; Creatine; Cyanides; Dinitrophenols; Extracellular Space; Histological Techniques; In Vitro Techniques; Lysine; Mannitol; Phenylalanine; Sulfates; Tyrosine; Urea | 1970 |
Fractionation of the nonpolar transfer ribonucleic acids from rat liver, yeast, and Escherichia coli by partition chromatography.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Chromatography; Chromatography, Gel; Cysteine; Escherichia coli; Genetic Code; Glutamates; Leucine; Liver; Lysine; Methionine; Nucleosides; Phenylalanine; Rats; RNA, Transfer; Saccharomyces; Serine; Species Specificity; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Evidence for inhibition by brain serotonin of mouse killing behaviour in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Brain; Humans; Injections, Intraperitoneal; Limbic System; Male; Methylation; Mice; Pargyline; Phenylalanine; Rats; Serotonin; Serotonin Antagonists; Tyrosine | 1971 |
Chorismate mutase-prephenate dehydratase. Phenylalanine-induced dimerization and its relationship to feedback inhibition.
Topics: Alanine; Allosteric Regulation; Bromine; Centrifugation, Density Gradient; Chromatography; Chromatography, Gel; Cyclohexanecarboxylic Acids; Cyclohexanes; Feedback; Genetics, Microbial; Hydro-Lyases; Hydrogen-Ion Concentration; Isomerases; Kinetics; Macromolecular Substances; Mercuribenzoates; Models, Biological; Molecular Weight; Mutation; Phenylalanine; Protein Binding; Pyruvates; Salmonella typhimurium; Thiophenes; Tyrosine; Ultracentrifugation | 1971 |
Selective inactivation of amino acid acceptor and ribosome-binding activities of Escherichia coli tRNA by modification with cyanogen bromide.
Topics: Acylation; Amino Acyl-tRNA Synthetases; Arginine; Binding Sites; Carbon Isotopes; Chemical Phenomena; Chemistry; Cyanogen Bromide; Escherichia coli; Glutamates; Glutamine; Glycine; Guanine Nucleotides; Histidine; Isoleucine; Kinetics; Lysine; Methylamines; Nucleic Acid Conformation; Phenylalanine; Polynucleotides; Ribosomes; RNA, Transfer; Structure-Activity Relationship; Thiouracil; Tyrosine; Uracil Nucleotides; Uridine; Valine | 1971 |
Enzyme alterations in tyrosine and phenylalanine auxotrophs of Salmonella typhimurium.
Topics: Cell-Free System; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Culture Media; Cyclohexanecarboxylic Acids; Cyclohexanes; Enzyme Repression; Genetic Complementation Test; Genetics, Microbial; Hydro-Lyases; Mutation; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Phosphotransferases; Pyruvates; Salmonella typhimurium; Tyrosine | 1971 |
[Inactivation of E. coli transfer RNA (phenylalanine and lysine) by gamma-radiation].
Topics: Adenine; Binding Sites; Carbon Isotopes; Chromatography, DEAE-Cellulose; Cobalt Isotopes; Escherichia coli; Isoleucine; Lysine; Oxygen; Peptide Biosynthesis; Peptide Chain Elongation, Translational; Phenylalanine; Polynucleotides; Radiation Dosage; Radiation Effects; RNA, Transfer; Time Factors; Transfer RNA Aminoacylation; Tyrosine; Uracil | 1971 |
Simple and rapid procedure for chromatographic identification of multiple transfer RNA species from Escherichia coli.
Topics: Benzoates; Carbon Isotopes; Chromatography, DEAE-Cellulose; Cysteine; Escherichia coli; Ethanol; Isotope Labeling; Methods; Phenylalanine; RNA, Transfer; Sulfur Isotopes; Tryptophan; Tyrosine | 1971 |
Temperature control of initiation of protein synthesis in Escherichia coli.
Topics: Amino Acids; Bacterial Proteins; Carbon Isotopes; Centrifugation; Coliphages; Electrophoresis, Disc; Escherichia coli; Magnesium; Methionine; Molecular Weight; Phenylalanine; Proline; Ribosomes; RNA, Transfer; Sulfur Isotopes; Temperature; Tritium; Tyrosine; Viral Proteins | 1971 |
Control of aromatic acid biosynthesis in Bacillus subtilis: sequenial feedback inhibition.
Topics: Bacillus subtilis; Feedback; Hydro-Lyases; In Vitro Techniques; Ligases; Oxidoreductases; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1966 |
Multiple proteolytic enzymes of Bacillus licheniformis.
Topics: Amidohydrolases; Aminopeptidases; Bacillus; Carboxypeptidases; Chromatography, Gel; Edetic Acid; Esterases; Fluorides; Hot Temperature; Hydrogen-Ion Concentration; Isoflurophate; Metals; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Substrate specificity of elastolytic and nonelastolytic proteinases from Pseudomonas aeruginosa.
Topics: Arginine; Asparagine; Chromatography; Glutamates; Glycine; Insulin; Lysine; Pancreatic Elastase; Peptide Hydrolases; Peptides; Phenylalanine; Pseudomonas aeruginosa; Sulfonic Acids; Tyrosine | 1966 |
Tryptophan- and indole-excreting prototrophic mutant of Escherichia coli.
Topics: Carbonic Anhydrases; Enzyme Repression; Escherichia coli; Indoles; Ligases; Mutagens; Mutation; Phenylalanine; Tryptophan; Tyrosine | 1964 |
Amino-acid protection of ultra-violet-irradiated Bacillus subtilis.
Topics: Acid-Base Equilibrium; Alanine; Bacillus subtilis; Culture Media; Glycine; Histidine; Phenylalanine; Proline; Radiation Effects; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
Phenyl-hydroxylation with tetrahydropterin as activator.--A model for the enzymic synthesis of tyrosine.
Topics: Chemical Phenomena; Chemistry; Models, Theoretical; Phenylalanine; Pterins; Tyrosine | 1967 |
[Demonstration and genetic separation of two PODH-aldolases subjected to retroinhibition in S. cerevisiae].
Topics: Enzyme Repression; Fructose-Bisphosphate Aldolase; Phenylalanine; Saccharomyces; Tyrosine | 1967 |
[Biosynthesis of the aglycons of mycosides A and B].
Topics: Carbon Isotopes; Chromatography, Thin Layer; Glycols; Glycosides; Models, Biological; Mycobacterium; Mycobacterium tuberculosis; Phenols; Phenylalanine; Propionates; Spectrophotometry; Spectrum Analysis; Tyrosine | 1967 |
Comparative control of a branch-point enzyme in microorganisms.
Topics: Actinomycetales; Aeromonas; Aminobenzoates; Bacillus; Bacteria; Benzoates; Culture Media; Cyclohexanecarboxylic Acids; Enterobacter; Erwinia; Escherichia; Feedback; Fungi; Isoenzymes; Ligases; Micrococcus; Phenylalanine; Proteus; Pseudomonas; Salmonella; Serratia; Streptococcus; Tryptophan; Tyrosine; Xanthomonas | 1967 |
In vitro growth inhibition of S-91 mouse melanomas by tyrosinase substrate analogs with and without L-cysteine.
Topics: Animals; Catechol Oxidase; Chemical Phenomena; Chemistry; Cysteine; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1967 |
[Regulation of biosynthesis of aromatic amino acids by Calviceps paspali].
Topics: Aldehyde-Lyases; Amino Acids; Ascomycota; Cellulose; Centrifugation, Zonal; Chromatography, Ion Exchange; Enzyme Inhibitors; Isoenzymes; Ligases; Models, Biological; Oxidoreductases; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1967 |
Itoic acid synthesis in Bacillus subtilis.
Topics: Bacillus subtilis; Benzoates; Carbon Isotopes; Glycine; Iron; ortho-Aminobenzoates; Phenylalanine; Tryptophan; Tyrosine | 1968 |
Studies on amino-acyl-sRNA synthetases from Pseudomonas and methionyl-sRNA. I. Partial purification of leucyl-, phenylalanyl-, tyrosyl-, and synthetases.
Topics: Chromatography; Isoleucine; Leucine; Ligases; Methionine; Phenylalanine; Phosphorus Isotopes; Pseudomonas aeruginosa; RNA, Bacterial; RNA, Transfer; Tyrosine | 1967 |
The nature of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in extracts of wild-type Neurospora crassa: a reaction controlled by two activating substrates and three allosteric negative modifiers.
Topics: Aldehyde-Lyases; Cobalt; Edetic Acid; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Neurospora; Phenylalanine; Phosphates; Pyruvates; Spectrophotometry; Tryptophan; Tyrosine | 1968 |
"Fetal PKU:" the effect of maternal hyperphenylalaninemia during pregnancy in the rhesus monkey (Macaca mulatta).
Topics: Amino Acids; Animals; Animals, Newborn; Birth Weight; Diet; Female; Fetal Diseases; Haplorhini; Humans; Intellectual Disability; Learning; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Serine; Tyrosine | 1968 |
Comparative aspects of tyrosine hydroxylase and tryptophan hydroxylase inhibition: arterenones and dihydroxyphenylacetamide (H 22-54).
Topics: Acetophenones; Adrenal Medulla; Amides; Animals; Brain; Cattle; Iron; Mast-Cell Sarcoma; Methyltyrosines; Mice; Mixed Function Oxygenases; Norepinephrine; Phenylacetates; Phenylalanine; Sarcoma, Experimental; Tritium; Tryptophan; Tyrosine | 1968 |
Oxidation of phenolic compounds by Mycobacterium leprae and inhibition of phenolase by substrate analogues and copper chelators.
Topics: Animals; Basidiomycota; Catechol Oxidase; Chelating Agents; Copper; Humans; Melanoma; Mice; Mycobacterium; Mycobacterium leprae; Phenols; Phenylalanine; Tyrosine | 1968 |
Studies on the intracellular localization of tetracycline in bacteria.
Topics: Bacillus cereus; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry; Chromatography, Paper; Culture Media; Densitometry; Drug Resistance, Microbial; Escherichia coli; Fluorometry; Hydrogen-Ion Concentration; Isoleucine; Leucine; Nucleotides; Peptide Biosynthesis; Phenylalanine; Ribosomes; Spectrophotometry; Tetracycline; Tritium; Tyrosine; Uracil Nucleotides; Valine | 1968 |
Cross pathway regulation: effect of histidine on the synthesis and activity of enzymes of aromatic acid biosynthesis in Bacillus subtilis.
Topics: Bacillus subtilis; Cyclohexanecarboxylic Acids; Enzyme Repression; Heptoses; Histidine; Ligases; Mutation; Oxidoreductases; Phenylalanine; Phosphotransferases; Pyruvates; Shikimic Acid; Tyrosine | 1968 |
Comparison of the specificities of various serine proteinases from microorganisms.
Topics: Amino Acids; Aspergillus; Bacillus subtilis; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Chymotrypsin; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Peptide Hydrolases; Peptides; Phenylalanine; Protease Inhibitors; Serine; Streptomyces; Tyrosine | 1969 |
Isolation of amino acid transport-negative mutants of Pseudomonas aeruginosa and cells with repressed transport activity.
Topics: Amino Acids; Arginine; Biological Transport; Carbon Isotopes; Enzyme Repression; Membrane Transport Proteins; Mutation; Phenylalanine; Proline; Pseudomonas aeruginosa; Tryptophan; Tyrosine | 1969 |
Regulated enzymes of aromatic amino acid synthesis: control, isozymic nature, and aggregation in Bacillus subtilis and Bacillus licheniformis.
Topics: Bacillus; Bacillus subtilis; Enzyme Repression; Genetics, Microbial; Ligases; Molecular Biology; Phenylalanine; Phosphotransferases; Shikimic Acid; Transferases; Tryptophan; Tyrosine | 1969 |
Detection of phenylketonuria carriers.
Topics: Female; Genetics, Medical; Humans; Male; Mass Screening; Methods; New York; Phenylalanine; Phenylketonurias; Sampling Studies; Tyrosine | 1969 |
Effect of calcium ion on S-100, a protein of the nervous system.
Topics: Acrylates; Animals; Antigens; Brain Chemistry; Calcium; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cysteine; Electrophoresis; Fluorometry; Immune Sera; Immunodiffusion; Magnesium; Methods; Nerve Tissue Proteins; Optical Rotatory Dispersion; Phenylalanine; Potassium; Protein Binding; Protein Denaturation; Quaternary Ammonium Compounds; Rabbits; Sodium; Solubility; Spectrophotometry; Strontium; Sulfhydryl Compounds; Time Factors; Tryptophan; Tyrosine; Urea; Viscosity | 1969 |
Incorporation of 5-methyl- and 5-hydroxy-tryptophan into the protein of Bacillus subtilis.
Topics: Amino Acids; Bacillus subtilis; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Thin Layer; Culture Media; Lysine; Phenylalanine; Protein Hydrolysates; Ribosomes; Serotonin; Starvation; Tryptophan; Tyrosine; Uracil | 1970 |
Regulation of chemoautotrophic metabolism. II. Competition between amino acids for incorporation into Thiobacillus.
Topics: Amino Acids; Carbon Isotopes; Depression, Chemical; Phenylalanine; Pseudomonas aeruginosa; Thiobacillus; Tryptophan; Tyrosine | 1969 |
Synthesis of a cyclic decapeptide corresponding to tyrocidine E.
Topics: Amino Acid Sequence; Bacillus; Bacillus subtilis; Chromatography, Ion Exchange; Culture Media; Dimethyl Sulfoxide; Peptides; Phenylalanine; Staphylococcus; Tyrosine | 1970 |
Derepression of tyrosinase synthesis in Neurospora by amino acid analogs.
Topics: Amino Acids; Catechol Oxidase; Enzyme Induction; Enzyme Repression; Ethionine; Mutation; Neurospora; Phenylalanine; Tyrosine | 1970 |
[Experimental hyperphenylalanaemic animals and cystathionine contents in brain tissues].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Brain Chemistry; Diet; Dipeptides; Disease Models, Animal; Haplorhini; Hydro-Lyases; L-Serine Dehydratase; Male; Metabolic Diseases; Mixed Function Oxygenases; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rats; Swine; Tyrosine | 1970 |
Regulation of the chorismic acid branch-point in aromatic acid synthesis in blue-green and green algae.
Topics: Acids; Cell-Free System; Chlorophyta; Cyanobacteria; Cyclohexanecarboxylic Acids; Depression, Chemical; Ligases; Phenylalanine; Phosphotransferases; Species Specificity; Spectrum Analysis; Stimulation, Chemical; Tryptophan; Tyrosine | 1969 |
[Autoradiographic study of the disorder of protein synthesis in the mouse liver following CCL4 intoxication. Dose-effect graphs for reversible and irreversible damages].
Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; Female; Liver; Mice; Microscopy, Fluorescence; Phenylalanine; Protein Biosynthesis; Tritium; Tyrosine | 1970 |
An effect of temperature on the Bacillus subtillis transfer RNA's which respond to codons beginning with U and A correlation with cytokinin activity.
Topics: Adenine; Bacillus subtilis; Binding Sites; Chromatography, DEAE-Cellulose; Cystine; Ethanol; Genetic Code; Hot Temperature; Kinins; Leucine; Phenylalanine; RNA, Bacterial; RNA, Transfer; Serine; Sodium Chloride; Tryptophan; Tyrosine; Uridine | 1970 |
Renal amino acid reabsorption in hyperphenylalaninemic monkeys infused with beta-2-thienylalanine.
Topics: Amino Acids; Animals; Blood Specimen Collection; Haplorhini; Humans; Kidney Tubules; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1970 |
Transfer RNA patterns in livers of rats fed diets containing 3'-methyl-4-dimethylaminoazobenzene.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Chromatography; Female; Histidine; Leucine; Liver Diseases; Lysine; Methionine; Methylation; p-Dimethylaminoazobenzene; Phenylalanine; Precancerous Conditions; Rats; RNA, Transfer; Serine; Threonine; Tritium; Tyrosine; Valine | 1970 |
[Demands on screening tests in inborn anomalies of metabolism].
Topics: Bacillus subtilis; Chromatography; Chromatography, Paper; Culture Media; Galactose; Histidine; Humans; Infant, Newborn; Leucine; Mass Screening; Metabolism, Inborn Errors; Methionine; Phenylalanine; Tyrosine | 1970 |
Plasma amino acid levels in diabetic ketoacidosis.
Topics: Adolescent; Adult; Aged; Alanine; Amino Acids; Arginine; Butyrates; Child; Citrulline; Cystine; Diabetic Ketoacidosis; Female; Glycine; Histidine; Humans; Insulin; Isoleucine; Leucine; Lysine; Male; Methionine; Middle Aged; Ornithine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1970 |
A new microbial product, oudenone, inhibiting tyrosine hydroxylase.
Topics: Animals; Antihypertensive Agents; Bacteria; Basidiomycota; Blood Pressure; Catechol Oxidase; Chemical Phenomena; Chemistry; Infrared Rays; Phenylalanine; Rats; Solubility; Spectrum Analysis; Tyrosine; Ultraviolet Rays | 1970 |
The inhibition of intestinal absorption of phenylalanine in the rhesus monkey.
Topics: Alanine; Animals; Diet; Haplorhini; Intestinal Absorption; Leucine; Male; Phenylalanine; Tryptophan; Tyrosine | 1970 |
Possible inhibitory effect of teichoic acid on Bacillus subtilis transfer ribonucleic acid.
Topics: Bacillus subtilis; Chromatography, DEAE-Cellulose; Chromatography, Gel; Histidine; Ligases; Pentosephosphates; Phenylalanine; Polysaccharides, Bacterial; RNA, Transfer; Tyrosine | 1970 |
Metabolic interlock. The multi-metabolite control of prephenate dehydratase activity in Bacillus subtilis.
Topics: Bacillus subtilis; Cyclohexanes; Feedback; Hydro-Lyases; Leucine; Methionine; Mutation; Phenylalanine; Pyruvates; Tryptophan; Tyrosine | 1970 |
Transport of aromatic amino acids by Pseudomonas aeruginosa.
Topics: Amino Acids; Autoradiography; Biological Transport; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Genetics, Microbial; Glucose; Mutation; Phenylalanine; Pseudomonas aeruginosa; Tryptophan; Tyrosine | 1971 |
Phenylalanine tolerance tests in simian primates.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Chromatography, Ion Exchange; Haplorhini; Monkey Diseases; Phenylalanine; Stereoisomerism; Tyrosine | 1971 |
Metabolic interlock. The role of the subordinate type of enzyme in the regulation of a complex pathway.
Topics: Bacillus subtilis; Binding Sites; Cell-Free System; Cyclohexanecarboxylic Acids; Enzyme Repression; Feedback; Genetics, Microbial; Hybridization, Genetic; Isomerases; Mutation; Phenylalanine; Pyruvates; Shikimic Acid; Tryptophan; Tyrosine | 1971 |
The effect of tyrosyl modification on the activity of -lactalbumin in the lactose synthetase reaction.
Topics: Albumins; Amino Acids; Animals; Catechol Oxidase; Cattle; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electrophoresis, Disc; Galactose; Glucose; Histidine; Iodine; Kinetics; Macromolecular Substances; Milk; Nitro Compounds; Nucleoside Diphosphate Sugars; Phenylalanine; Transferases; Tryptophan; Tyrosine; Uracil Nucleotides | 1971 |
Some biochemical and pharmacological actions of -methylphenylalanine.
Topics: Adrenal Glands; Amphetamine; Animals; Avoidance Learning; Blood Pressure; Brain; Brain Chemistry; Brain Stem; Carbon Isotopes; Chromatography, Ion Exchange; Chromatography, Paper; Chromatography, Thin Layer; Dogs; Dopamine; Electric Stimulation; Epinephrine; Haplorhini; Heart; Heart Atria; Heart Rate; Heart Ventricles; Metaraminol; Methyltyrosines; Mice; Mixed Function Oxygenases; Myocardium; Norepinephrine; Phenethylamines; Phenylalanine; Rats; Reserpine; Serotonin; Time Factors; Tyrosine | 1970 |
Partial purification and enzymatic properties of an aminopeptidase from barley.
Topics: Amides; Aminopeptidases; Ammonium Sulfate; Aniline Compounds; Chemical Precipitation; Chloromercuribenzoates; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Dipeptides; Dithiothreitol; Drug Stability; Edetic Acid; Edible Grain; Electrophoresis, Disc; Enzyme Activation; Hydrogen-Ion Concentration; Hydroxyapatites; Isoflurophate; Leucine; Mercaptoethanol; Methionine; Molecular Weight; Naphthalenes; Nitro Compounds; Peptides; Phenylalanine; Plants; Spectrophotometry; Tyrosine | 1971 |
Separation and properties of isozymes of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthetase from Saccharomyces cerevisiae.
Topics: Aldehyde-Lyases; Chromatography, Affinity; Chromatography, Thin Layer; Cobalt; Dipeptides; Drug Stability; Edetic Acid; Glycine; Heptoses; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Manganese; Molecular Weight; Phenylalanine; Phosphoenolpyruvate; Saccharomyces; Saccharomyces cerevisiae; Temperature; Tryptophan; Tyrosine; Zinc | 1971 |
3-D-eoxy-D-arabino-heptulosonate-7-phosphate synthase of Streptomyces aureofaciens Tü 24. II. Repression and inhibition by tryptophan and tryptophan analogues.
Topics: 5-Hydroxytryptophan; Aldehyde-Lyases; Allosteric Regulation; Enzyme Repression; Hydrogen-Ion Concentration; Phenylalanine; Phosphoenolpyruvate; Stereoisomerism; Streptomyces; Streptomyces aureofaciens; Tetroses; Tryptophan; Tyrosine | 1971 |
The non-enzymic hydroxylation of phenylalanine to tyrosine by 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine.
Topics: Air; Carbon Isotopes; Catalase; Chemical Phenomena; Chemistry; Chromatography, Paper; Coenzymes; Cyanides; Dihydroxyphenylalanine; Edetic Acid; Hydrogen Peroxide; Hydroxylation; Iron; Peroxides; Phenylalanine; Phenylalanine Hydroxylase; Pteridines; Sulfhydryl Compounds; Tyrosine | 1971 |
Mydriatic response to phenylalanine, tyrosine, dopa, and dopamine in Bufo viridis.
Topics: Animals; Anura; Bufonidae; Chelating Agents; Dihydroxyphenylalanine; Disulfiram; Dopamine; Drug Interactions; Edetic Acid; Eye; Female; Fentanyl; In Vitro Techniques; Iris; Male; Mydriatics; Phenylalanine; Time Factors; Tyrosine | 1970 |
Tyrosinemia induced by a pyridoxine antagonist, desoxypyridoxine.
Topics: Depression, Chemical; Female; In Vitro Techniques; Lactation; Liver; Liver Cirrhosis; Male; Metabolic Diseases; Metabolism; Methanol; Phenylalanine; Pregnancy; Pyridines; Pyridoxine; Tyrosine; Urine; Vitamin B 6 Deficiency | 1972 |
Effects of -radiation on concentrated solutions of -chymotrypsin.
Topics: Air; Albumins; Anilides; Carbamates; Caseins; Chymotrypsin; Cobalt Isotopes; Electrophoresis; Esters; Hemoglobins; Hydrochloric Acid; Imidazoles; Leucine; Nitro Compounds; Nitrogen; Nitrophenols; Peptides; Phenylalanine; Radiation Effects; Radiochemistry; Riboflavin; Solutions; Structure-Activity Relationship; Tryptophan; Tyrosine | 1972 |
Effects of hydrogen bonding and temperature upon the near ultraviolet circular dichroism and absorption spectra of tyrosine and O-methyl tyrosine derivatives.
Topics: Acetamides; Acetates; Alcohols; Chemical Phenomena; Chemistry; Circular Dichroism; Dioxins; Esters; Ethanol; Ethers; Macromolecular Substances; Methanol; Methylation; Methyltyrosines; Phenylalanine; Solvents; Spectrophotometry; Stearic Acids; Temperature; Tyrosine; Ultraviolet Rays | 1972 |
Specificity of Aeromonas aminopeptidase toward amino acid amides and dipeptides.
Topics: Aeromonas; Alanine; Amides; Amino Acids; Aminocaproates; Aminopeptidases; Dipeptides; Glycine; Isoleucine; Kinetics; Leucine; Methionine; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine; Valerates; Valine | 1972 |
[Biochemistry of phenylketonuria].
Topics: Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1972 |
[Therapy of phenylketonuria].
Topics: Diet Therapy; Humans; Methionine; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 1972 |
[Hyperphenylalaninemia and other hyperaminoacidurias with mental retardation, detected by multiple screening].
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Humans; Infant, Newborn; Intellectual Disability; Mass Screening; Phenylalanine; Tyrosine | 1972 |
Structural specificity in the intestinal transport of hexoses, tyrosine derivatives and electrolytes in freshwater catfish.
Topics: Animals; Bicarbonates; Biological Transport, Active; Carbon Isotopes; Chlorides; Dihydroxyphenylalanine; Fishes; Fucose; Galactose; Glucose; Hexoses; In Vitro Techniques; Intestinal Mucosa; Intestine, Small; Membrane Potentials; Ouabain; Phenylalanine; Phlorhizin; Sodium; Solutions; Structure-Activity Relationship; Tyrosine | 1972 |
Free amino acids in ram seminal plasma.
Topics: Amino Acids; Animals; Cell Count; Isoleucine; Leucine; Male; Phenylalanine; Semen; Sheep; Spermatozoa; Tyrosine | 1972 |
What is the best age to discontinue the low phenylalanine diet in phenylketonuria? A presentation of some contributory data.
Topics: Adolescent; Age Factors; Behavior; Child; Child, Preschool; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Intelligence; Intelligence Tests; Male; Methods; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine; Visual Perception | 1972 |
Energy metabolism in the brains of L-phenylalanine-treated chicks.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Brain; Chickens; Fructosephosphates; Glucose; Glucosephosphates; Glycerophosphates; Glycogen; Glycolysis; Hypoxia, Brain; Lactates; Male; Phenylacetates; Phenylalanine; Stereoisomerism; Tyrosine; Unconsciousness | 1972 |
Regional and subcellular distribution of aminotransferases in rat brain.
Topics: Alanine; Alanine Transaminase; Aminobutyrates; Animals; Asparagine; Aspartate Aminotransferases; Brain; Cerebral Cortex; Corpus Callosum; Glutamates; Glutamine; Glyoxylates; Ketoglutaric Acids; Male; Mesencephalon; Methionine; Ornithine; Oxaloacetates; Phenylalanine; Rats; Sciatic Nerve; Spinal Cord; Subcellular Fractions; Transaminases; Tyrosine | 1972 |
Persistent hyperphenylalaninemia.
Topics: Age Factors; Body Weight; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1972 |
The use of deuterated phenylalanine for the elucidation of the phenylalanine-tyrosine metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, Gas; Deuterium; Humans; Hydroxylation; Infant; Lactates; Mass Spectrometry; Methods; Phenols; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1972 |
Amniotic fluid amino acids in maternal phenylketonuria.
Topics: Adult; Amino Acids; Amniotic Fluid; Diet Therapy; Female; Gestational Age; Humans; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1972 |
Problems in the biochemical detection of heterozygotes for phenylketonuria.
Topics: Autoanalysis; Chromatography, Ion Exchange; Female; Heterozygote; Humans; Methods; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1972 |
Genetic control of immune response in mice to a glutamic acid, lysine, phenylalanine copolymer. 3. Use of recombinant inbred strains of mice to establish association of immune response genes with H-2 genotype.
Topics: Alleles; Animals; Antibodies; Antibody Formation; Antigen-Antibody Reactions; Antigens; Cross Reactions; Genes, Dominant; Genotype; Glutamates; Histocompatibility; Immunogenetics; Iodine Isotopes; Isoantigens; Lysine; Mice; Mice, Inbred Strains; Phenylalanine; Polymers; Recombination, Genetic; Tyrosine | 1972 |
A rapid chromatographic determination of phenylalanine and tyrosine for phenylketonuria screening.
Topics: Autoanalysis; Buffers; Chromatography, Ion Exchange; Computers; Female; Humans; Indicators and Reagents; Infant, Newborn; Ion Exchange Resins; Male; Mass Screening; Methods; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Tyrosine | 1972 |
Hereditary tyrosinemia: metabolic studies in a patient with partial p-hydroxyphenylpyruvate hydroxylase activity.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Catecholamines; Diet Therapy; Humans; Infant; Kidney Tubules; Levulinic Acids; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Tyrosine | 1972 |
Quantitative changes in plasma amino acids in patients with renal disease.
Topics: Adult; Amino Acids; Chromatography, Paper; Fasting; Female; Humans; Kidney Diseases; Male; Mathematics; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine; Urea | 1972 |
Kinetics of influx of phenylalanine, tyrosine, tryptophan, histidine and leucine into slices of brain cortex from adult and 7-day-old rats.
Topics: Amino Acids; Animals; Biological Transport, Active; Cerebral Cortex; Histidine; Leucine; Phenylalanine; Rats; Tritium; Tryptophan; Tyrosine | 1972 |
Metabolism of aromatic acids in plant organelles.
Topics: Cinnamates; Hydroxylation; Magnoliopsida; Organoids; Phenylalanine; Plant Cells; Plants; Plants, Toxic; Ricinus; Tryptophan; Tyrosine | 1972 |
Specificity in enzyme inhibition. 2. -Aminohydroxamic acids as inhibitors of histidine decarboxylase and 3,4-dihydroxyphenylalanine decarboxylase.
Topics: Alanine; Amino Acids; Aromatic Amino Acid Decarboxylase Inhibitors; Binding Sites; Carboxy-Lyases; Drug Antagonism; Histidine; Hydroxamic Acids; Imidazoles; Models, Chemical; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1972 |
Phenylalanine hydroxylase activity in riboflavin deficient rats.
Topics: Animals; Injections, Intraperitoneal; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Proteins; Rats; Riboflavin; Riboflavin Deficiency; Tyrosine | 1972 |
Local and systemic effects of phenylalanine on intestinal transport of tyrosine and tryptophan.
Topics: Amino Acids; Animals; Diet; Electrophoresis; Female; Glucose; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Methods; Perfusion; Phenylalanine; Rats; Rats, Inbred Strains; Spectrophotometry; Tryptophan; Tyrosine | 1972 |
Screening for inherited metabolic disease by plasma chromatography (Scriver) in a large city.
Topics: Amino Acid Metabolism, Inborn Errors; Blood Specimen Collection; Chromatography, Paper; Costs and Cost Analysis; Fasting; Food; Histidine; Humans; Hyperlipidemias; Infant, Newborn; Mass Screening; Methionine; Midwifery; Phenylalanine; Phenylketonurias; Postal Service; Proline; Time Factors; Tyrosine; United Kingdom | 1972 |
Circular dichroism of intramolecularly hydrogen-bonded acetylamino acid amides.
Topics: Acetates; Alanine; Amides; Amino Acids; Bradykinin; Chemical Phenomena; Chemistry; Circular Dichroism; Glycine; Methylamines; Optical Rotatory Dispersion; Peptides; Phenylalanine; Proline; Protein Conformation; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1972 |
Net metabolism of plasma amino acids by liver and portal-drained viscera of fed sheep.
Topics: Alanine; Amino Acids; Ammonia; Animal Feed; Animals; Arginine; Aspartic Acid; Blood Flow Velocity; Dietary Proteins; Digestive System; Glutamates; Glutamine; Glycine; Isoleucine; Leucine; Liver; Liver Circulation; Nitrogen; Ornithine; Phenylalanine; Serine; Sheep; Tyrosine; Valine | 1972 |
[Concentration changes of free amino acids in blood plasma of patients under radiotherapy. (With reference to statistical results)].
Topics: Alanine; Amino Acids; Bronchial Neoplasms; Carcinoma; Cobalt Isotopes; Dysgerminoma; Esophageal Neoplasms; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Leucine; Male; Neoplasms; Phenylalanine; Proline; Radiation Injuries; Sex Factors; Statistics as Topic; Tyrosine; Urinary Bladder Neoplasms; Valine | 1972 |
[Detection of heterozygotes of typical phenylketonuria].
Topics: Adult; Chromatography; Female; Heterozygote; Humans; Male; Mass Screening; Phenylalanine; Phenylketonurias; Tyrosine | 1972 |
Amino acids in amniotic fluid: changes in concentrations during the first half of pregnancy.
Topics: Abortion, Therapeutic; Adult; Alanine; Amino Acids; Amniotic Fluid; Arginine; Chromatography, Ion Exchange; Female; Gestational Age; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Serine; Tyrosine; Valine | 1972 |
Amino acid patterns in the blood plasma of the young bovine.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Cystine; Female; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1972 |
[Rapid separation of aromatic and ramified amino acids by chromatography on ion exchange columns. Application to the surveillance of leucinosis and hyperphenylalaninemia].
Topics: Amino Acids; Chromatography, Ion Exchange; Humans; Isoleucine; Leucine; Maple Syrup Urine Disease; Methionine; Methods; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1972 |
Plasma amino acid response in young men given diets devoid of single essential amino acids.
Topics: Adolescent; Adult; Amino Acids; Deficiency Diseases; Dietary Proteins; Fasting; Female; Humans; Isoleucine; Leucine; Lysine; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1972 |
[Alkaptonuria and ochronosis].
Topics: Alkaptonuria; Chemical Phenomena; Chemistry; Diagnosis, Differential; Female; Germany, West; Homogentisic Acid; Humans; Male; Middle Aged; Ochronosis; Phenols; Phenylalanine; Radiography; Sex Factors; Spinal Diseases; Tyrosine | 1972 |
Band-shape analysis and display of fine structure in protein spectra: a new approach to perturbation spectroscopy.
Topics: Acetates; Animals; Apoproteins; Aspartate Aminotransferases; Cattle; Chymotrypsinogen; Computers; Cysteine; Egg White; Ethanol; Glucagon; Mathematics; Methods; Muramidase; Myocardium; Pancreas; Phenylalanine; Protein Conformation; Protein Denaturation; Ribonucleases; Spectrophotometry; Swine; Tryptophan; Tyrosine; Ultraviolet Rays; Urea | 1972 |
Effects of n-alkyl ligands on the difference spectra of bovine and human serum albumin.
Topics: Acetates; Animals; Binding Sites; Cattle; Fatty Acids, Nonesterified; Fatty Alcohols; Glycols; Humans; Oleic Acids; Phenylalanine; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrophotometry; Sulfonic Acids; Sulfuric Acids; Surface-Active Agents; Tyrosine; Ultraviolet Rays | 1972 |
The labelling of proteins by irradiation in tritiated water.
Topics: Alkylation; Amino Acids; Animals; Cetacea; Chromatography, Ion Exchange; Cysteine; Egg White; Endopeptidases; Histidine; Isotope Labeling; Leucyl Aminopeptidase; Muramidase; Myoglobin; Phenylalanine; Photolysis; Pronase; Radiation Effects; Tritium; Tryptophan; Tyrosine; Ultraviolet Rays; Water; Wool | 1972 |
[Biochemical studies on the age-related variations of the human intervertebral disc].
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Chromatography; Collagen; Galactosamine; Glucosamine; Hexosamines; Humans; Infant; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Phenylalanine; Potassium; Sodium; Thoracic Vertebrae; Tryptophan; Tyrosine | 1972 |
New protein reagents. II. 4-chloro-3,5-dinitrophenacyl bromide.
Topics: Acetophenones; Animals; Bromine; Carboxylic Acids; Cattle; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Thin Layer; Diazomethane; Histidine; Hydrolysis; Indicators and Reagents; Nitrates; Nitro Compounds; Pancreas; Phenylalanine; Ribonucleases; Spectrophotometry; Sulfhydryl Compounds; Tryptophan; Tyrosine; Ultraviolet Rays | 1972 |
Biological evaluation of a whey protein fraction, with special reference to its use as a phenylalanine-low protein source in the dietary treatment of PKU.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Biological Assay; Body Weight; Cattle; Chemical Phenomena; Chemistry; Chickens; Diet Therapy; Dietary Proteins; Eggs; Elements; Humans; Male; Milk; Nitrogen; Phenylalanine; Phenylketonurias; Rats; Tyrosine; Vitamins | 1972 |
[Pathophysiology of blood-brain barrier--with special referance to transport of glucose and amino acid to the brain].
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Biological Transport; Blood-Brain Barrier; Brain; Cats; Glucose; Glutamates; Perfusion; Phenylalanine; Radioisotopes; Tyrosine | 1972 |
Comparison of the surface structures of choline-less Torulopsis pintolopesii grown on defined media with choline or methionine.
Topics: Amino Acids; Candida; Cell Fractionation; Cell Wall; Choline; Culture Media; Ethylenediamines; Glucose; Lipids; Mannose; Methionine; Mitosporic Fungi; Phenylalanine; Phosphorus; Proteins; Time Factors; Tritium; Tyrosine; Vitamin D | 1972 |
Stimulation of rat liver phenylalanine hydroxylase activity by derivatives of vitamin E.
Topics: Animals; Carbon Isotopes; Centrifugation; Humans; Kinetics; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phosphoric Acids; Pteridines; Rats; Sodium Dodecyl Sulfate; Structure-Activity Relationship; Succinates; Tyrosine; Ultracentrifugation; Vitamin E | 1972 |
Contribution of tyrosine to circular dichroism changes accompanying neurophysin-hormone interaction.
Topics: Animals; Cattle; Circular Dichroism; Disulfides; Electrophoresis, Disc; Hydrogen-Ion Concentration; Nerve Tissue Proteins; Nitro Compounds; Oxytocin; Peptides; Phenylalanine; Protein Binding; Tyrosine; Ultraviolet Rays; Vasopressins | 1972 |
Maternal hyperphenylalaninaemia in the normal and phenylketonuric mother and its influence on maternal plasma and fetal fluid amino acid concentrations.
Topics: Adult; Amino Acids; Amniotic Fluid; Female; Fetus; Humans; Hysterectomy; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1972 |
Incorporation of phenylalanine, tyrosine and tryptophan into protein of homogenates from developing rat brain: kinetics of incorporation and reciprocal inhibition.
Topics: Age Factors; Animals; Brain; Nerve Tissue Proteins; Phenylalanine; Rats; Tritium; Tryptophan; Tyrosine | 1972 |
Brain serotonin content: physiological regulation by plasma neutral amino acids.
Topics: Amino Acids; Animals; Brain Chemistry; Dietary Carbohydrates; Dietary Proteins; Hydroxyindoleacetic Acid; Isoleucine; Leucine; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1972 |
Conformational energy calculations of enzyme-substrate interactions. I. Computation of preferred conformations of some substrates of -chymotrypsin.
Topics: Chymotrypsin; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1972 |
Subtilisin; a stereochemical mechanism involving transition-state stabilization.
Topics: Alanine; Arginine; Benzyl Compounds; Binding Sites; Catalysis; Chemical Phenomena; Chemistry; Drug Stability; Endopeptidases; Glycine; Leucine; Macromolecular Substances; Models, Chemical; Models, Structural; Peptides; Phenylalanine; Structure-Activity Relationship; Tyrosine; X-Ray Diffraction | 1972 |
Studies on the mechanism of antigenic competition: analysis of competition between synthetic polypeptide antigens.
Topics: Alanine; Animals; Antibody Formation; Antigens; Coliphages; Glutamine; Hemagglutination Tests; Immune Sera; Immunization; Immunization, Secondary; Immunologic Memory; Lysine; Mice; Mice, Inbred C3H; Peptides; Phenylalanine; Tyrosine | 1972 |
Purification and properties of phenylalanine ammonia-lyase from plant tissue cultures.
Topics: Ammonia-Lyases; Cinnamates; Coumarins; Culture Techniques; Phenylalanine; Plants; Tyrosine | 1972 |
The effect of pyridoxine deficiency on intestinal absorption of amino acids and peptides in the rat.
Topics: Alanine; Amino Acids; Animals; Dipeptides; Glycine; Intestinal Absorption; Jejunum; Leucine; Male; Methanol; Penicillamine; Peptides; Phenylalanine; Pyridines; Rats; Tyrosine; Vitamin B 6 Deficiency | 1972 |
Purification and properties of a peptidase from thyroid glands.
Topics: Acetone; Animals; Cattle; Chloromercuribenzoates; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Paper; Citrates; Diiodotyrosine; Electrophoresis; Ethylmaleimide; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Insulin; Iodides; Iodoacetates; Isoflurophate; Ketones; Kidney; Kinetics; Oxidation-Reduction; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Rats; Sheep; Species Specificity; Sulfonic Acids; Swine; Thyroid Gland; Toluene; Tyrosine; Ultracentrifugation | 1971 |
Ligand exchange amino acid analysis: resolution of some amino sugars and cysteine derivatives.
Topics: Acetates; Amino Acids; Arginine; Autoanalysis; Buffers; Cysteine; Galactose; Glucosamine; Hexosamines; Histidine; Hydrogen-Ion Concentration; Ion Exchange Resins; Mannose; Methods; Ovalbumin; Phenylalanine; Sodium; Tyrosine; Zinc | 1971 |
Transamination of amino acids in homogenates of rat brzain.
Topics: Age Factors; Alanine; Amino Acids; Animals; Animals, Newborn; Asparagine; Aspartic Acid; Brain; Chromatography; Culture Media; Electrophoresis, Paper; Glutamates; Glutamine; Isoleucine; Ketoglutaric Acids; Male; Methionine; Organ Culture Techniques; Ornithine; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine; Valine | 1971 |
[Transitional tyrosinemia of premature infants].
Topics: Humans; Infant, Newborn; Infant, Premature, Diseases; Oxidoreductases; Phenylalanine; Phenylpyruvic Acids; Tyrosine | 1971 |
[Hyperphenylalaninemia with cerebral damage].
Topics: Brain Damage, Chronic; Child; Female; Glomerular Filtration Rate; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1971 |
Physical and chemical properties of the bovine neurophysins.
Topics: Alanine; Amides; Amino Acids; Animals; Binding Sites; Calcium; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Cystine; Dipeptides; Electrophoresis, Disc; Glycine; Histidine; Hydrogen-Ion Concentration; Macromolecular Substances; Methionine; Models, Biological; Molecular Weight; Oxytocin; Peptides; Phenylalanine; Pituitary Gland, Posterior; Potentiometry; Protein Binding; Protein Conformation; Proteins; Spectrophotometry; Tyrosine; Ultracentrifugation; Ultraviolet Rays; Vasopressins | 1971 |
Substrate specificity of the intracellular proteinase from a slow acid producing mutant of Streptococcus lactis.
Topics: Alanine; Amino Acids; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Histidine; Hydrolysis; Insulin; Leucine; Lysine; Mutation; Oxidation-Reduction; Peptide Hydrolases; Phenylalanine; Protein Binding; Streptococcus; Tyrosine; Valine | 1971 |
Effect of excess levels of individual amino acids on growth of rats fed casein diets.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Cystine; Depression, Chemical; Dietary Proteins; DNA; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Organ Size; Phenylalanine; Proline; Proteins; Rats; RNA; Serine; Stereoisomerism; Stimulation, Chemical; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Amino acid supplementation of opaque-2 corn diets for growing rats.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cystine; Dietary Proteins; Growth; Isoleucine; Lysine; Male; Methionine; Nitrogen; Nutritional Requirements; Phenylalanine; Rats; Stimulation, Chemical; Threonine; Tyrosine; Valine; Zea mays | 1971 |
Developmental changes in amino acid concentrations in human amniotic fluid: abnormal findings in maternal phenylketonuria.
Topics: Adult; Amino Acids; Amniotic Fluid; Chromatography; Congenital Abnormalities; Female; Fetal Diseases; Gestational Age; Humans; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1971 |
-chymotrypsin: selective hydrolysis of tyrosyl-tRNA Tyr and phenylalanyl-tRNA Phe .
Topics: Chymotrypsin; Hydrolysis; Phenylalanine; RNA, Transfer; Tyrosine | 1971 |
Quantitative amino acids in amniotic fluid and maternal plasma in early and late pregnancy. Preliminary report.
Topics: Alanine; Amino Acids; Aminobutyrates; Amniotic Fluid; Arginine; Aspartic Acid; Citrulline; Cystine; Female; Gestational Age; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Determination of metabolites of tyrosine and of tryptophan and related compounds by gas-liquid chromatography.
Topics: Animals; Chromatography, Gas; Indoles; Kynurenine; Phenylalanine; Rats; Serotonin; Silicon; Tryptamines; Tryptophan; Tyrosine | 1971 |
The biosynthesis of chelidonic acid.
Topics: Acetates; Aspartic Acid; Carbon Dioxide; Carbon Isotopes; Citric Acid Cycle; Culture Media; Dicarboxylic Acids; Glucose; Models, Biological; Oxidation-Reduction; Phenylalanine; Photosynthesis; Plants; Plants, Medicinal; Pyrans; Pyruvates; Ribose; Species Specificity; Tyrosine | 1971 |
Detection of phenylketonuric heterozygotes.
Topics: Chromatography, Ion Exchange; Female; Heterozygote; Humans; Indicators and Reagents; Methods; Phenylalanine; Phenylketonurias; Population Surveillance; Pregnancy; Tyrosine | 1971 |
Near-ultraviolet absorption bands of tryptophan. Studies using horseradish peroxidase isoenzymes, bovine and horse heart cytochrome c, and N-stearyl-L-tryptophan n-hexyl ester.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Cold Temperature; Cyclohexanes; Cytochromes; Energy Transfer; Esters; Glycerol; Heme; Horses; Hydrogen-Ion Concentration; Indoles; Isoenzymes; Myocardium; Peroxidases; Phenylalanine; Plants; Spectrophotometry; Stearic Acids; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Degeneration of the eyes and central nervous system of chick embros subjected to phenylalanine or tyrosine deficiency.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Nucleus; Central Nervous System; Chick Embryo; Culture Media; Eye; Leucine; Microscopy, Electron; Nerve Degeneration; Nutritional Requirements; Phenylalanine; Pigments, Biological; Retinal Degeneration; Tritium; Tyrosine | 1971 |
Biosynthesis of dithiadiketopiperazine antibiotics: comparison of possible aromatic amino acid precusors.
Topics: Alkaloids; Anti-Bacterial Agents; Ascomycota; Aspergillus; Carbon Isotopes; Dihydroxyphenylalanine; Indoles; Ketones; Mass Spectrometry; Mitosporic Fungi; Oxepins; Penicillium; Phenylalanine; Piperazines; Sulfides; Time Factors; Tritium; Tyrosine | 1971 |
Quantitative protein sequencing using mass spectrometry: mass spectral analysis of 2-anilino-5-thiazolinone derivatives of amino acids without prior conversion to the phenyl thiohydantoins.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Aniline Compounds; Animals; Arginine; Autoanalysis; Cattle; Chemical Phenomena; Chemistry; Drug Stability; Glutamates; Hydantoins; Lysine; Mass Spectrometry; Methods; Phenylalanine; Ribonucleases; Serine; Sulfides; Thiazoles; Thiocyanates; Threonine; Tyrosine | 1971 |
Ontogenesis of phenylalanine and tryptophan hydroxylation in rat brain and liver.
Topics: Animals; Animals, Newborn; Brain; Carbon Isotopes; Chromatography; Female; Fetus; Injections, Intraperitoneal; Injections, Spinal; Liver; Mixed Function Oxygenases; Phenylalanine; Pregnancy; Rats; Tryptophan; Tyrosine | 1971 |
Daily variations in the concentrations of individual amino acids in rat plasma.
Topics: Alanine; Amino Acids; Animals; Circadian Rhythm; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Phenylalanine; Rats; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Active transport of glutamate in Streptomyces hydrogenans. I. Studies on uptake and pool size, and their interrelationship.
Topics: Aminoisobutyric Acids; Arginine; Asparagine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Cold Temperature; Culture Media; Dinitrophenols; Glutamate Dehydrogenase; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Mathematics; Methionine; Osmosis; Phenylalanine; Protein Biosynthesis; Stereoisomerism; Streptomyces; Temperature; Tyrosine | 1971 |
Peptides with terminal tyrosyl and phenylalanyl groups.
Topics: Animals; Blood Pressure; Dogs; Female; Injections, Intravenous; Peptides; Phenylalanine; Rats; Tyrosine; Uterus; Vasoconstrictor Agents | 1971 |
Optical rotatory dispersion and circular dichroism of mono- and oligonucleotide-amino acids (amidates).
Topics: Adenine Nucleotides; Alanine; Amines; Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Circular Dichroism; Cytosine Nucleotides; Deoxyribonucleotides; Electrophoresis, Paper; Guanine Nucleotides; Inosine Nucleotides; Methylamines; Models, Structural; Nucleotides; Optical Rotatory Dispersion; Phenylalanine; Polynucleotides; Thymine Nucleotides; Tryptophan; Tyrosine; Ultraviolet Rays; Uracil Nucleotides | 1971 |
Studies on the conformation of amino acids. V. Conformation of amino acids with delta-atoms.
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Histidine; Leucine; Models, Structural; Phenylalanine; Thermodynamics; Tryptophan; Tyrosine | 1971 |
The chymotrypsinogens and procarboxypeptidases of chick pancreas.
Topics: Acetates; Amylases; Animals; Benzoates; Carboxypeptidases; Chickens; Chromatography, DEAE-Cellulose; Chymotrypsin; Chymotrypsinogen; Endopeptidases; Enzyme Activation; Enzyme Precursors; Hippurates; Lactates; Leucine; Lipase; Methanol; Pancreas; Phenylalanine; Trypsin; Trypsinogen; Tryptophan; Tyrosine | 1971 |
Effects of totally synthetic, low phenylalanine diet on adolescent phenylketonuric patients.
Topics: Adolescent; Amino Acids; Body Weight; Child; Child Behavior Disorders; Diet Therapy; Electroencephalography; Female; Growth; Humans; Male; Neurologic Manifestations; Phenylalanine; Phenylketonurias; Tyrosine; Vitamins | 1971 |
The effect of dietary fluoride on plasma free amino acid concentrations in the rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Diet; Feeding Behavior; Female; Fluorides; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rats; Rats, Inbred Strains; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
The effects of DL-p-fluorophenylalanine and L-3-nitrotyrosine on the growth and biochemistry of the Taper liver tumor.
Topics: Animals; Carbon Isotopes; Depression, Chemical; Fluorine; In Vitro Techniques; Liver Neoplasms; Mice; Neoplasm Proteins; Nitro Compounds; Phenylalanine; RNA, Transfer; Tyrosine | 1971 |
p-Azido-L-phenylalanine: a photo-affinity 'probe' related to tyrosine.
Topics: Chromatography, Thin Layer; Magnetic Resonance Spectroscopy; Optical Rotation; Phenylalanine; Spectrum Analysis; Tyrosine; Ultraviolet Rays | 1971 |
Analysis in human plasma of 3-methoxytyrosine: a metabolite of DOPA.
Topics: Chromatography, Ion Exchange; Dihydroxyphenylalanine; Ethers; Fasting; Humans; Mass Spectrometry; Parkinson Disease; Phenylalanine; Tyrosine | 1971 |
Marine bacterial proteases. II. Peptide specificity of an endopeptidase produced by Vibrio B-30.
Topics: Benzyl Compounds; Caseins; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Dipeptides; Electrophoresis; Endopeptidases; Formates; Hemoglobins; Hydrolysis; Insulin; Nitrobenzenes; Paper; Peptides; Phenylalanine; Ribonucleases; Tyrosine; Vibrio | 1971 |
On the specificity of tryptic catalysis.
Topics: 1-Propanol; Acetates; Acylation; Arginine; Benzoates; Catalysis; Chemical Phenomena; Chemistry; Citrulline; Esters; Glycine; Kinetics; Lysine; Methanol; Models, Biological; Ornithine; Phenylalanine; Protein Binding; Sulfonic Acids; Thermodynamics; Toluene; Trypsin; Tyrosine | 1971 |
Phenylalanine absorption and metabolism in Parkinsonian patients.
Topics: Administration, Oral; Aged; Female; Half-Life; Humans; Injections, Intravenous; Intestinal Absorption; Male; Middle Aged; Parkinson Disease; Phenylalanine; Tyrosine | 1971 |
The effect of vitamin C depletion on the free amino acid content in blood plasma of the guinea pig.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Ascorbic Acid Deficiency; Aspartic Acid; Citrulline; Cysteine; Glutamates; Glycine; Guinea Pigs; Histidine; Isoleucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Proline; Serine; Threonine; Time Factors; Tyrosine; Valine | 1971 |
The determination of urinary phenylacetylglutamine as phenylacetic acid. Studies on its origin in normal subjects and children with cystic fibrosis.
Topics: Administration, Oral; Capsules; Child; Child, Preschool; Chromatography, Gas; Chromatography, Ion Exchange; Circadian Rhythm; Cystic Fibrosis; Diet; Female; Glutamine; Humans; Hydrolysis; Infant; Infant, Newborn; Lactates; Male; Phenethylamines; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Time Factors; Tyramine; Tyrosine | 1971 |
Experience with a screening service, using the Guthrie test, in the north-west and north-east metropolitan regions.
Topics: Amino Acid Metabolism, Inborn Errors; Biological Assay; Homocystinuria; Humans; Infant; Mass Screening; Methionine; Phenylalanine; Phenylketonurias; Tyrosine | 1971 |
Problems of phenylketonuria.
Topics: Child, Preschool; Chromatography, Thin Layer; Humans; Infant; Infant, Newborn; Mandelic Acids; Mass Screening; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1971 |
The effect of diethyl pyrocarbonate on the transfer RNA of bovine muscle.
Topics: Alanine; Amino Acyl-tRNA Synthetases; Animals; Aspartic Acid; Carbon Isotopes; Carbonates; Cattle; Chemical Phenomena; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Diaphragm; Histidine; Lens, Crystalline; Leucine; Liver; Lysine; Methionine; Muscles; Phenylalanine; Rats; RNA, Transfer; Serine; Tyrosine; Valine | 1971 |
[Clinical problems of the genetic heterogeneity in hyperphenylalaninemias].
Topics: Administration, Oral; Amino Acid Metabolism, Inborn Errors; Brain Diseases; Child; Child, Preschool; Diagnosis, Differential; Diet Therapy; Dietary Proteins; Electroencephalography; Female; Humans; Phenylalanine; Phenylketonurias; Protein Deficiency; Tyrosine | 1971 |
Dietary treatment of adult patients with phenylketonuria.
Topics: Adult; Diet Therapy; Electroencephalography; Evaluation Studies as Topic; Female; Humans; Male; Phenylalanine; Phenylketonurias; Pilot Projects; Psychological Tests; Psychomotor Disorders; Time Factors; Tyrosine | 1971 |
Organ-specific inhibition of human alkaline phosphatase isoenzymes of liver, bone, intestine and placenta; L-phenylalanine, L-tryptophan and L homoarginine.
Topics: Alkaline Phosphatase; Amino Acids; Bile Acids and Salts; Bone and Bones; Cysteine; Dihydroxyphenylalanine; Guanidines; Histidine; Humans; Intestines; Isoenzymes; Liver; Organ Specificity; Phenylalanine; Phosphoric Acids; Placenta; Stereoisomerism; Structure-Activity Relationship; Tryptophan; Tyrosine | 1971 |
Comparative study of various serine proteinases from microorganisms: specificity with oligopeptides.
Topics: Alanine; Aspergillus; Bacillus; Binding Sites; Chromatography, Gel; Chromatography, Ion Exchange; Electrophoresis, Disc; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Leucine; Peptides; Phenylalanine; Protease Inhibitors; Serine; Species Specificity; Streptomyces; Tyrosine | 1971 |
[Determination of phenylalanine hydroxylase activity in liver homogenates of healthy test persons].
Topics: Adult; Age Factors; Aged; Biopsy; Female; Humans; Liver; Male; Middle Aged; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Sex Factors; Spectrometry, Fluorescence; Tyrosine | 1971 |
Hyperphenylalanaemia and the exchange of tyrosine in adult rat brain.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Blood-Brain Barrier; Brain; Metabolic Clearance Rate; Nerve Tissue Proteins; Phenylalanine; Protein Binding; Rats; Tritium; Tyrosine | 1971 |
[Routine thin-layer-chromatography in 25000 newborn infants. Comparison with the Guthrie-tests].
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography, Thin Layer; Histidine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Leucine; Mass Screening; Methionine; Methods; Phenylalanine; Tyrosine | 1971 |
The isolation and properties of the protein calliphorin.
Topics: Amino Acids; Animals; Carbohydrates; Cystine; Diptera; Electrophoresis; Guanidines; Hydrogen-Ion Concentration; Immune Sera; Immunoelectrophoresis; Larva; Methionine; Microscopy, Electron; Molecular Weight; Phenylalanine; Proteins; Pupa; Tyrosine; Ultracentrifugation | 1971 |
Tyrosinosis: biochemical studies of an unusual case.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Autoanalysis; Chromatography, Gas; Chromatography, Paper; Diet; Female; Humans; Intellectual Disability; Phenylalanine; Tyrosine | 1971 |
Spectral properties of cobalt carboxypeptidase. The effects of substrates and inhibitors.
Topics: Acetates; Animals; Benzoates; Binding Sites; Butyrates; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; Cobalt; Enzyme Activation; Glycine; Hydrogen-Ion Concentration; Lactates; Light; Pancreas; Peptides; Phenylalanine; Propionates; Spectrum Analysis; Tyrosine | 1971 |
The extraction of a protein fraction rich in glycine, serine, tyrosine, and phenylalanine from Merino wool.
Topics: Animals; Chromatography; Dialysis; Electrophoresis, Disc; Ethanol; Glycine; Molecular Weight; Phenylalanine; Proteins; Serine; Sheep; Tyrosine; Wool | 1971 |
Catalytic properties of oligomeric -chymotrypsin.
Topics: Acetates; Anilides; Animals; Catalysis; Cattle; Chymotrypsin; Glutarates; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mathematics; Nitro Compounds; Osmolar Concentration; Phenylalanine; Succinates; Temperature; Tyrosine; Ultracentrifugation | 1971 |
Interactions of tyrosine and tyramine with nucleic acids and their components. Fluorescence, nuclear magnetic resonance and circular dichroism studies.
Topics: Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Cattle; Circular Dichroism; Cold Temperature; Cytidine; Cytosine Nucleotides; DNA; Ethers; Fluorometry; Guanine Nucleotides; Magnetic Resonance Spectroscopy; Mathematics; Nucleic Acid Conformation; Phenylalanine; Polynucleotides; Serotonin; Sodium Chloride; Temperature; Thymidine; Thymus Gland; Tyramine; Tyrosine; Ultraviolet Rays | 1971 |
Uptake of alanine, phenylalanine and tyrosine by L1210 cells at 4 degrees C: possible effect of lipid solubility.
Topics: Alanine; Animals; Cold Temperature; Culture Media; Culture Techniques; Hydroxylation; Leukemia L1210; Mice; Phenylalanine; Phospholipids; Tyrosine | 1971 |
Affinity labeling of bovine carboxypeptidase A Leu by N-bromoacetyl-N-methyl-L-phenylalanine. I. Kinetics of inactivation.
Topics: Acetates; Animals; Binding Sites; Bromine; Carbon Isotopes; Carboxypeptidases; Cattle; Chemical Phenomena; Chemistry; Chromatography; Dipeptides; Glycine; Hydrogen-Ion Concentration; Indoleacetic Acids; Kinetics; Mathematics; Phenylacetates; Phenylalanine; Phenylbutyrates; Propionates; Protein Binding; Spectrophotometry; Stereoisomerism; Tyrosine | 1971 |
[Amino acid analysis of UV-irradiated ribonuclease A].
Topics: Amino Acid Sequence; Animals; Arginine; Cattle; Cystine; Glycine; Methionine; Pancreas; Phenylalanine; Radiation Effects; Ribonucleases; Tyrosine; Ultraviolet Rays | 1971 |
The characterization of hereditary abnormalities of keratin: Clouston's ectodermal dysplasia.
Topics: Ectodermal Dysplasia; Genes, Dominant; Hair; Humans; Keratosis; Nails, Malformed; Phenylalanine; Proline; Serine; Sulfur; Tyrosine; Urea; Water | 1971 |
Determination of urinary aromatic acids by gas chromatography. Results from healthy infants and from patients with phenylketonuria.
Topics: Child; Child, Preschool; Chromatography, Gas; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Phenylketonurias; Tyrosine | 1971 |
The influence of short-range interactions on protein conformation. I. Side chain-backbone interactions within a single peptide unit.
Topics: Alanine; Amino Acid Sequence; Arginine; Asparagine; Aspartic Acid; Binding Sites; Cystine; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Muramidase; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
The Guthrie screening test for phenylketonuria: a report on two years participation in the national programme.
Topics: Humans; Infant, Newborn; Infant, Newborn, Diseases; Mass Screening; Methods; New Zealand; Phenylalanine; Phenylketonurias; State Medicine; Tyrosine | 1969 |
The growth-stimulating activity of peptides on human hematopoietic cell cultures.
Topics: Alanine; Amino Acids; Cell Division; Cell Line; Culture Media; Culture Techniques; Dipeptides; Growth Substances; Hematopoiesis; Humans; Kinetics; Leukemia, Myeloid, Acute; Lymphocyte Activation; Lymphocytes; Peptides; Phenylalanine; Tryptophan; Tyrosine; Valine | 1969 |
Phenylketonuria: a family study.
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
Effect of vitamin B 6 on blood 5-hydroxytryptamine concentration.
Topics: Animals; Animals, Newborn; Birth Weight; Body Weight; Brain; Carboxy-Lyases; Desoxycorticosterone; Diet; Female; Fetus; Humans; In Vitro Techniques; Indoleacetic Acids; Infant; Infant, Newborn; Kidney; Liver; Phenylalanine; Phenylketonurias; Postpartum Period; Pregnancy; Pyridoxine; Rats; Serotonin; Tryptophan; Tyrosine; Umbilical Cord; Vitamin B 6 Deficiency | 1969 |
The assessment of serum amino acids.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Chromatography, Paper; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Renal Aminoacidurias; Tyrosine | 1970 |
Abnormal phenylalanine loading tests in mothers of children with cleft defects.
Topics: Adult; Cleft Lip; Cleft Palate; Female; Humans; Phenylalanine; Tyrosine | 1970 |
Isoaccepting transfer RNA's of L-M cells in culture and after tumor induction in C3H mice.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cell Line; Chromatography; Connective Tissue; Culture Media; Culture Techniques; Female; Fibrosarcoma; Glycine; Histidine; Isoleucine; Leucine; Ligases; Lysine; Male; Methionine; Mice; Phenylalanine; Proline; RNA, Transfer; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Distribution of free amino acids in plasma in patients with a chronic lymphatic and acute leukemia].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Citrulline; Cystine; Glutamates; Glutamine; Glycine; Histidine; Humans; Isoleucine; Leucine; Leukemia, Lymphoid; Lysine; Methionine; Ornithine; Phenylalanine; Prednisolone; Proline; Serine; Threonine; Triethylenemelamine; Tyrosine; Valine; Vincristine | 1971 |
Serotonin deficiency in infancy as a cause of a mental defect in experimental phenylketonuria.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Chlorpromazine; Electroshock; Female; Humans; In Vitro Techniques; Intellectual Disability; Learning; Male; Melatonin; Mice; Neurosecretion; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Reserpine; Serotonin; Tryptamines; Tyrosine; Urine | 1965 |
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine | 1966 |
Urinary exeretion of phenolic and indolic compounds, metacatecholamines, and VMA by full-term and premature infants.
Topics: 5-Hydroxytryptophan; Benzoates; Catecholamines; Cinnamates; Creatinine; Humans; Indoleacetic Acids; Infant, Newborn; Infant, Premature; Kynurenine; Lactates; Mandelic Acids; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Phthalic Acids; Propionates; Tryptophan; Tyrosine | 1968 |
[The amino acid composition of human lens proteins in the course of lens alterations and cataract transformation. I. The amino acid composition of unclouded human lenses of various age groups].
Topics: Adult; Age Factors; Aged; Aging; Alanine; Amino Acids; Arginine; Asparagine; Cataract; Crystallins; Glutamates; Glycine; Humans; Isoleucine; Lens, Crystalline; Leucine; Lysine; Middle Aged; Nitrogen; Peptide Hydrolases; Phenylalanine; Tyrosine | 1966 |
Studies of brain aminotransferase and psychotropic agents. I. Interaction of B-B'-iminodipropionitrile and rat brain aromatic aminotransferases.
Topics: 5-Hydroxytryptophan; Aminopropionitrile; Animals; Brain; Brain Chemistry; Chromatography; Chromatography, Gel; Female; Kinetics; Nitriles; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyrosine | 1969 |
Activity of aromatic aminotransferases in rat brain.
Topics: 5-Hydroxytryptophan; Age Factors; Amino Acids; Animals; Brain; Dihydroxyphenylalanine; Fetus; Histidine; Humans; Infant, Newborn; Methods; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine | 1968 |
X- and gamma-radiolysis of some tryptophan dipeptides.
Topics: Alanine; Chromatography, Thin Layer; Glycine; Leucine; Models, Chemical; Peptides; Phenylalanine; Radiation Effects; Tryptophan; Tyrosine | 1970 |
DL-[2-14C]p-chlorophenylalanine as an inhibitor of tryptophan 5-hydroxylase.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Paper; Dialysis; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Pyruvates; Rats; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
Alpha-keto analogues of amino acids as inhibitors of alpha-chymotrypsin, carboxypeptidase A, and pepsin.
Topics: Caproates; Carboxypeptidases; Chymotrypsin; Enzymes; Indoleacetic Acids; Indoles; Keto Acids; Ketoglutaric Acids; Kinetics; Lactates; Pepsin A; Phenylalanine; Phenylpyruvic Acids; Propionates; Pyruvates; Tryptophan; Tyrosine | 1965 |
Control of aromatic biosynthesis: the multiplicity of 7-phospho-2-oxo-3-deoxy-D-arabino-heptonate D-erythrose-4-phosphate-lyase (pyruvate-phosphorylating) in Escherichia coli W.
Topics: Aldehyde-Lyases; Amino Acids; Chemistry Techniques, Analytical; Enzyme Repression; Enzymes; Escherichia coli; In Vitro Techniques; Isoenzymes; Phenylalanine; Shikimic Acid; Tryptophan; Tyrosine | 1965 |
Control of three isoenzymic 7-phospho-2-oxo-3-deoxy-Darabino-heptonate-D-erythrose-4-phosphate lyases of Escherichia coli W and derived mutants by repressive and "inductive" effects of the aromatic amino acids.
Topics: Aldehyde-Lyases; Enzyme Induction; Enzyme Repression; Escherichia coli; Isoenzymes; Molecular Biology; Mutation; Phenylalanine; Shikimic Acid; Tryptophan; Tyrosine | 1966 |
Genetic and biochemical analysis of the isoenzymes concerned in the first reaction of aromatic biosynthesis in Escherichia coli.
Topics: Amino Acids; Chromatography; Chromosome Mapping; Enzyme Repression; Escherichia coli; Isoenzymes; Ligases; Mutation; Phenylalanine; Tryptophan; Tyrosine | 1967 |
Induction of capsular polysaccharide synthesis by rho-fluorophenylalanine in Escherichia coli wild type and strains with altered phenylalanyl soluble ribonucleic acid synthetase.
Topics: Antimetabolites; Carbon Isotopes; Enzyme Induction; Enzymes; Escherichia coli; Ligases; Mutation; Phenylalanine; Polysaccharides, Bacterial; RNA, Bacterial; Tritium; Tyrosine | 1967 |
Inhibition of protein synthesis by aminoacyl 3'-(2')-adenosine.
Topics: Bacterial Proteins; Chromatography; Escherichia coli; Leucine; Nucleosides; Phenylalanine; RNA, Messenger; Tyrosine; Valine | 1966 |
Stimulation of amino acid incorporation into protein by polyuridylic-8-azaguanylic acid.
Topics: Azaguanine; Bacterial Proteins; Escherichia coli; Genetic Code; Leucine; Phenylalanine; Polynucleotides; Tyrosine; Uracil Nucleotides; Valine | 1966 |
Imidazolylacetolphosphate:L-glutamate aminotransferase. Composition and substructure.
Topics: Alanine; Ammonia; Arginine; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry, Physical; Electrophoresis; Genes; Glycine; Histidine; Leucine; Methionine; Molecular Biology; Molecular Weight; Peptides; Phenylalanine; Proline; Salmonella typhimurium; Serine; Threonine; Transaminases; Tyrosine; Valine | 1967 |
[On the origin of the oxygen of the carboxyl group of the product formed in the course of pepsin-catalysed transpeptidation reactions].
Topics: Animals; In Vitro Techniques; Oxygen Consumption; Pepsin A; Peptide Hydrolases; Peptides; Phenylalanine; Tyrosine | 1965 |
2-aminotyrosine, an analog of tyrosine.
Topics: Chemistry, Organic; Escherichia coli; Eubacterium; Organic Chemistry Phenomena; Phenylalanine; Photometry; Tyrosine | 1966 |
Beta-pyrrolo-L-alanine, a new antimetabolite of phenylalanine and tyrosine in Escherichia coli.
Topics: Alanine; Antimetabolites; Chemistry, Organic; Escherichia coli; Organic Chemistry Phenomena; Phenylalanine; Pyrroles; Tryptophan; Tyrosine | 1966 |
Studies on the specificity of pepsin.
Topics: Amino Acid Sequence; Animals; Chemical Phenomena; Chemistry; Chemistry, Organic; Enzymes; Ethers; Histidine; Kinetics; Leucine; Organic Chemistry Phenomena; Pepsin A; Peptides; Phenylalanine; Spectrophotometry; Swine; Tryptophan; Tyrosine | 1967 |
Genetic analysis of aromatic mutants of Salmonella typhimurium.
Topics: Amino Acids; Chromosome Mapping; Culture Media; Genes; Genetics; Mutation; Phenylalanine; Salmonella Phages; Salmonella typhimurium; Tryptophan; Tyrosine | 1967 |
Photoinduced perithecial formation by Nectria haematococca on media containing either L-tyrosine; L-phenylalanine; or D-glucose+NaNO3 as sole carbon and nitrogen sources.
Topics: Ascomycota; Culture Media; Glucose; Hydrogen-Ion Concentration; Light; Nitrates; Phenylalanine; Tyrosine | 1969 |
Electronic properties of N-heteroaromatics. XXXVI. Interaction of the carcinogenic 4-nitroquinoline 1-oxide with proteins and aromatic amino acids.
Topics: Albumins; Amino Acids; Carcinogens; Dialysis; Histidine; Phenylalanine; Protein Denaturation; Proteins; Quinolines; Ribonucleases; Spectrum Analysis; Tryptophan; Tyrosine | 1969 |
Quantitative chromatography of aromatic amino acids on Sephadex G-10.
Topics: Amino Acids; Caseins; Chromatography, Gel; Methods; Peptides; Phenylalanine; Protein Hydrolysates; Proteins; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1969 |
Resonance transfer of excitation energy between aromatic amino acids and carcinogenic aromatic compounds as a possible mechanism in carcinogenesis.
Topics: Amino Acids; Carcinogens; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1969 |
Electrochemical studies on the adsorption of amino acids in relation to the compatibility of prosthetic materials and the human body.
Topics: Adsorption; Alanine; Amino Acids; Arginine; Computers; Electrochemistry; Histidine; Hydroxyproline; Lysine; Phenylalanine; Proline; Prostheses and Implants; Surface Tension; Tryptophan; Tyrosine | 1969 |
Chloramphenicol-specific antibody. II. Reactivity to analogues of chloramphenicol.
Topics: Animals; Antibodies; Binding Sites; Cattle; Chloramphenicol; Chlorine; Complement Fixation Tests; Haptens; Immunochemistry; Nitrophenols; Phenylalanine; Propylene Glycols; Rabbits; Stereoisomerism; Tyrosine | 1969 |
[Determination of heterozygote carrier state of phenylketonuria gene].
Topics: Adult; Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
Structural comparison of the hemoglobins of the genus Equus with those of ruminants.
Topics: Alleles; Amino Acid Sequence; Amino Acids; Animals; Biological Evolution; Blood Protein Electrophoresis; Chemical Phenomena; Chemistry; Female; Glycine; Hemoglobins; Horses; Male; Methods; Models, Biological; Molecular Biology; Peptides; Perissodactyla; Phenylalanine; Polymorphism, Genetic; Serine; Sheep; Species Specificity; Tyrosine | 1969 |
[Blood amino acids in phenylketonuria. 11 cases].
Topics: Adolescent; Adult; Amino Acids; Child; Child, Preschool; Chromatography, Ion Exchange; Diet Therapy; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Statistics as Topic; Tyrosine | 1969 |
Maternal phenylalanine deprivation in the rat. Enzymatic and cellular liver changes in the offspring.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Body Weight; Deficiency Diseases; Deoxyribonucleases; Diet; Female; Histocytochemistry; Lactation; Liver; Microscopy, Electron; Oxygenases; Phenylalanine; Pregnancy; Pregnancy Complications; Rats; Tyrosine | 1969 |
Diurnal variations of serum phenylalanine in phenylketonuric children on low phenylalanine diet.
Topics: Child, Preschool; Circadian Rhythm; Diet Therapy; Fasting; Feeding Behavior; Humans; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1969 |
Serum free amino acid pattern in a Babinga pygmy adult population.
Topics: Adolescent; Adult; Age Factors; Amino Acids; Autoanalysis; Black People; Central African Republic; Ethnicity; Female; Hepatomegaly; Humans; Italy; Male; Phenylalanine; Sex Factors; Splenomegaly; Tyrosine; Urea | 1969 |
[Adjustment of the substrate as rate-determining step in the enzymatic cleavage of esters and amides by chymotrypsin A].
Topics: Acridines; Amides; Chemical Phenomena; Chemistry; Chymotrypsin; Esters; Fluoroacetates; Kinetics; Magnetic Resonance Spectroscopy; Phenylalanine; Temperature; Tyrosine | 1969 |
[Effect of hydrocortisone on protein synthesis in rat liver microsomes].
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Hydrocortisone; Injections, Intraperitoneal; Liver; Male; Microsomes, Liver; Phenylalanine; Protein Biosynthesis; Rats; Stimulation, Chemical; Tyrosine | 1969 |
Biosynthesis of chloramphenicol.
Topics: Aldehyde-Lyases; Carbon Isotopes; Chemical Phenomena; Chemistry; Chloramphenicol; Nitrogen; Phenylalanine; Radioisotopes; Serine; Shikimic Acid; Streptomyces; Tyrosine | 1969 |
Isosmotic regulation in isolated surviving nerves of Eriocheir sinensis Milne Edwards.
Topics: Adaptation, Physiological; Amino Acids; Ammonia; Animals; Cell Membrane Permeability; Crustacea; Hypotonic Solutions; Isoleucine; Leucine; Neurons; Osmotic Pressure; Phenylalanine; Proline; Seawater; Tyrosine; Valine; Water-Electrolyte Balance | 1969 |
Another population of phenylketonuria? Studies on atypical phenylketonurics.
Topics: Aged; Child; Child, Preschool; Electroencephalography; Female; Humans; Intelligence; Intelligence Tests; Male; Neurologic Examination; Pedigree; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Population Surveillance; Tyrosine | 1969 |
Effect of reserpine, alpha-methyl-p-tyrosine, p-chlorophenylalanine and pargyline on levorphanol-induced running activity in mice.
Topics: Animals; Brain; Levorphanol; Male; Mice; Motor Activity; Norepinephrine; Pargyline; Phenylalanine; Reserpine; Sympathetic Nervous System; Tyrosine | 1969 |
[Some indices of phenylalanine and tyrosine metabolism in children with phenylketonuria].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
Regulation of chemoautotrophic metabolism. I. Toxicity of phenylalanine to thiobacilli.
Topics: Amino Acids; Bacterial Proteins; Biological Assay; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Depression, Chemical; ortho-Aminobenzoates; Phenylalanine; Phenylpyruvic Acids; Shikimic Acid; Stimulation, Chemical; Thiobacillus; Tryptophan; Tyrosine | 1969 |
Regulation of chemoautotrophic metabolism. 3. DAHP synthetase in Thiobacillus neapolitanus.
Topics: Aldehyde-Lyases; Amino Acids; Bacterial Proteins; Depression, Chemical; Dialysis; Fluorides; Histidine; Hydrogen-Ion Concentration; Phenylalanine; Spectrophotometry; Thiobacillus; Tryptophan; Tyrosine | 1969 |
[Structural differences in specific tRNA].
Topics: Alanine; Glutamates; Histidine; Phenylalanine; RNA Nucleotidyltransferases; RNA, Transfer; Tyrosine | 1969 |
Mental retardation in a family with phenylketonuria and mild hyperphenylalaninemia.
Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Consanguinity; Female; Humans; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
[Amino acid excretion in urine and enzyme activities in blood of persons from 3 families with mental deficiency].
Topics: Acid Phosphatase; Adolescent; Adult; Alanine; Alkaline Phosphatase; Amino Acids; Aspartate Aminotransferases; Aspartic Acid; Chromatography, Thin Layer; Enzymes; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glutamates; Glycine; Humans; Intellectual Disability; L-Lactate Dehydrogenase; Leukocytes; Male; Middle Aged; Pedigree; Phenylalanine; Spectrophotometry; Tyrosine | 1969 |
Transaminase activity in sheep rumen content.
Topics: Alanine; Alanine Transaminase; Animals; Arginine; Aspartic Acid; Cysteine; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Methionine; Phenylalanine; Rumen; Serine; Sheep; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
[Chemical and physico-chemical properties of placental protein with antineoplastic effect].
Topics: Alanine; Amino Acids; Ammonia; Antineoplastic Agents; Arginine; Aspartic Acid; Chromatography, Ion Exchange; Electrophoresis; Female; Glutamates; Glycine; Histidine; Humans; Leucine; Lysine; Phenylalanine; Placenta; Proline; Proteins; Serine; Threonine; Tyrosine; Valine | 1969 |
Effects of UV- and x-rays on histones in vivo and in vitro.
Topics: Amino Acids; Animals; Cricetinae; Culture Techniques; Female; Histidine; Histones; Ovary; Phenylalanine; Radiation Effects; Radiochemistry; Tyrosine; Ultraviolet Rays | 1969 |
[A case of "classical" phenylketonuria with average intelligence].
Topics: Aged; Female; Humans; Intelligence; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
Genetic control of the uptake of amino acids in Aspergillus nidulans.
Topics: Alleles; Amino Acids; Aspergillus; Ethionine; Genes; Genes, Dominant; Genetic Linkage; Microbial Sensitivity Tests; ortho-Aminobenzoates; Phenylalanine; Recombination, Genetic; Transduction, Genetic; Tritium; Tyrosine | 1969 |
Genetic control of phenylalanine and tyrosine biosynthesis in Neurospora crassa.
Topics: Centrifugation, Density Gradient; Chromatography, Gel; Chromosome Mapping; Crosses, Genetic; Cyclohexanes; Enzyme Precursors; Hydro-Lyases; Molecular Biology; Mutation; Neurospora; Oxidoreductases; Phenylalanine; Phosphotransferases; Pyruvates; Tyrosine | 1969 |
Maternal phenylketonuria. Course of two pregnancies.
Topics: Adult; Amniotic Fluid; Birth Weight; Chromatography; Female; Growth; Heart Defects, Congenital; Hemorrhage; Humans; Infant, Newborn; Intellectual Disability; Lung; Lymphangiectasis; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine; Umbilical Cord; Vagina | 1969 |
Studies of the location of the tyrosyl residues in insulin. II.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Glycerol; Glycols; Hydrogen-Ion Concentration; Insulin; Methanol; Optical Rotatory Dispersion; Oxides; Peptides; Phenylalanine; Spectrophotometry; Spectrum Analysis; Sucrose; Trypsin; Trypsin Inhibitors; Tyrosine; Ultraviolet Rays; Zinc | 1969 |
[Tyrosinosis].
Topics: Abdomen, Acute; Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Diet Therapy; Fanconi Syndrome; Genes, Recessive; Humans; Infant; Infant, Newborn; Liver Cirrhosis; Phenylalanine; Rickets; Sepsis; Tyrosine | 1969 |
[Ochronotic arthropathy].
Topics: Amino Acid Metabolism, Inborn Errors; Humans; Joint Diseases; Male; Middle Aged; Ochronosis; Phenylalanine; Pigmentation Disorders; Radiography; Tyrosine | 1969 |
[Effect of tyrosine and phenylalanine deficiency on the monoamine oxidase activity of rat brain].
Topics: Animals; Brain; Brain Stem; Cerebellum; Deficiency Diseases; Monoamine Oxidase; Myocardium; Norepinephrine; Phenylalanine; Protein Deficiency; Rats; Serotonin; Tyrosine | 1969 |
Study on the amino acid composition in the cornea of hypophysectomized rat.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cornea; Cystine; Electrophoresis; Glutamates; Glycine; Growth Hormone; Histidine; Hypophysectomy; Leucine; Lysine; Methionine; Phenylalanine; Pituitary Gland; Rats; Serine; Threonine; Tyrosine | 1969 |
[Contribution to the study of elastin in human and experimental atheroma].
Topics: Adult; Age Factors; Aged; Alanine; Amino Acids; Animals; Aorta; Arteries; Arteriosclerosis; Elastin; Humans; Infant; Infant, Newborn; Lysine; Methods; Middle Aged; Phenylalanine; Rabbits; Tyrosine | 1969 |
Separation of amino acid naphthylamidases in human plasma on sephadex G-200 and DEAE-cellulose.
Topics: Alanine; Amides; Aminopeptidases; Arginine; Aspartic Acid; Calcium; Chromatography, DEAE-Cellulose; Chromatography, Gel; Enzyme Activation; Glutamates; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Lysine; Magnesium; Molecular Weight; Naphthalenes; Phenylalanine; Strontium; Time Factors; Tyrosine; Valine | 1969 |
Hyperphenylalaninemia: the effect of cerebral amino acid levels during development.
Topics: Age Factors; Amino Acids; Animals; Brain; Brain Chemistry; Brain Diseases; Injections, Subcutaneous; Myelin Sheath; Phenylalanine; Rats; Time Factors; Tyrosine | 1969 |
Clinical and biochemical observations of patients with atypical phenylketonuria.
Topics: Child, Preschool; Female; Humans; Infant; Male; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Tyrosine | 1970 |
The biosynthesis of isotope hybrid proteins for high resolution nuclear magnetic resonance studies by incorporation of [1H]amino acids into fully deuterated algae.
Topics: Alanine; Amino Acids; Deuterium; Eukaryota; Hydrogen; Leucine; Magnetic Resonance Spectroscopy; Methionine; Phenylalanine; Protein Biosynthesis; Tyrosine | 1970 |
Synthesis of proteins in cells infected with herpesvirus. 3. Relative amino acid content of various proteins formed after infection.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Culture Techniques; Electrophoresis; Herpesviridae; Isoleucine; Kidney; Lysine; Methionine; Phenylalanine; Protein Biosynthesis; Pseudorabies; Rabbits; Tritium; Tyrosine; Viral Proteins | 1970 |
Alterations of individual free amino acids in brain during acute hepatic coma.
Topics: Amino Acids; Animals; Brain Chemistry; Cerebral Cortex; Disease Models, Animal; Dogs; Hepatic Encephalopathy; Histidine; Liver; Models, Biological; Nitrogen; Phenylalanine; Tryptophan; Tyrosine; Water | 1970 |
Effects of drugs on tremor and increase in brain acetylcholine produced by oxotremorine in the rat.
Topics: Acetylcholine; Animals; Brain; Brain Chemistry; Male; Phenoxybenzamine; Phenylalanine; Propranolol; Rats; Reserpine; Thiocarbamates; Tremor; Tremorine; Tyrosine | 1970 |
Comparison of rat liver and calf thymus histone fractions by molecular exclusion chromatography and ultracentrifugation.
Topics: Acrylates; Amino Acids; Animals; Cattle; Cell Nucleus; Chemical Phenomena; Chemistry; Chromatography, Gel; Computers; Deoxyribonucleases; Dextrans; Electrophoresis, Disc; Gels; Histones; Hydrogen-Ion Concentration; Liver; Methods; Molecular Weight; Phenylalanine; Rats; Ribonucleases; Spectrophotometry; Thymus Gland; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 1970 |
Flavinyl peptides. 3. Studies of intramolecular interactions in flavinyl aromatic amino acids by proton magnetic resonance.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Esters; Flavins; Magnetic Resonance Spectroscopy; Models, Structural; Peptides; Phenylalanine; Temperature; Tryptophan; Tyrosine | 1970 |
Isoenzymes and allosteric inhibition of Neurospora crassa 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Topics: Aldehyde-Lyases; Binding Sites; Buffers; Carbohydrates; Chromatography, Gel; Isoenzymes; Maleates; Mutation; Neurospora; Phenylalanine; Phosphates; Pyruvates; Species Specificity; Tromethamine; Tryptophan; Tyrosine | 1970 |
Effect of excess phenylalanine and of other amino acids on brain development in the infant rat.
Topics: Amino Acids; Animals; Animals, Newborn; Arginine; Brain; Brain Chemistry; Cerebrosides; Cholesterol; DNA; Leucine; Lipids; Methionine; Nerve Tissue Proteins; Organ Size; Phenylalanine; Rats; Sulfates; Sulfur Isotopes; Tyrosine; Valine | 1970 |
The rotational isomerism of the aromatic amino acids by nuclear magnetic resonance.
Topics: Chemical Phenomena; Chemistry; Histidine; Magnetic Resonance Spectroscopy; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine | 1970 |
Characterization of amino acids and low-molecular-- weight peptides bound to cytoplasmic granules from the posterior pituitary.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cytoplasmic Granules; Dialysis; Dinitrophenols; Glutamates; Liver; Lysine; Molecular Weight; Oxytocin; Peptides; Phenylalanine; Pituitary Gland, Posterior; Rats; Spectrum Analysis; Tyrosine; Vasopressins | 1970 |
Screening the "normal" population in Massachusetts for phenylketonuria.
Topics: Adolescent; Adult; Aged; Amino Acids; Diet Therapy; Female; Humans; Intellectual Disability; Male; Mass Screening; Massachusetts; Phenylalanine; Phenylketonurias; Tyrosine | 1970 |
Peptidyl transfer RNA. X. The chemical synthesis of peptidyl transfer RNA containing hydroxy amino acids.
Topics: Carbon Isotopes; Hydrogen-Ion Concentration; Imides; Methods; Peptides; Phenylalanine; RNA, Transfer; Serine; Thiosulfates; Tyrosine | 1970 |
L-tryptophan antagonism of epinephrine-induced hyperglycemia in rats.
Topics: Animals; Blood Glucose; Epinephrine; Female; Histidine; Hyperglycemia; Phenylalanine; Rats; Time Factors; Tryptophan; Tyrosine | 1970 |
Regulation of aromatic amino acid biosynthesis in phenazine-producing strains of Pseudomonas.
Topics: Amino Acids; Isomerases; Phenazines; Phenylalanine; Pseudomonas; Species Specificity; Stereoisomerism; Tryptophan; Tyrosine | 1970 |
Kinetics and mechanism of oxidation-reduction reactions between pyridine nucleotides and flavins.
Topics: Alanine; Amino Acids; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Hot Temperature; Hydrocarbons; Kinetics; Nucleotides; Oxidation-Reduction; Peptides; Phenylalanine; Pyridines; Tryptophan; Tyrosine | 1970 |
Effect of selective inhibitors of tyrosine and tryptophan hydroxylases on self-stimulation in the rat.
Topics: Animals; Electric Stimulation; Hypothalamus; Male; Methyltyrosines; Mixed Function Oxygenases; Phenylalanine; Rats; Reserpine; Self Stimulation; Tryptophan; Tyrosine | 1970 |
Cerebral proteinases in the growing rat.
Topics: Animals; Arginine; Brain; Centrifugation; Chymotrypsin; Hydrogen-Ion Concentration; Nerve Tissue Proteins; Phenylalanine; Protein Denaturation; Rats; Spectrophotometry; Trypsin; Tyrosine | 1970 |
Compartmentation of glutamate metabolism in the developing brain: experiments with labelled glucose, acetate, phenylalanine, tyrosine and proline.
Topics: Acetates; Animals; Animals, Newborn; Aspartic Acid; Brain; Carbon Isotopes; Chromatography, Paper; Female; Glucose; Glutamates; Glutamine; Male; Mice; Phenylalanine; Proline; Tyrosine | 1970 |
Intelligent, small for dates baby born to oligophrenic phenylketonuric mother after low phenylalanine diet during pregnancy.
Topics: Adult; Birth Weight; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Intelligence; Intelligence Tests; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine; Umbilical Arteries | 1970 |
Amino acid interactions in chick nutrition. 1. The interrelationship between lysine and arginine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Aspartic Acid; Body Weight; Chickens; Cobalt; Copper; Electrolytes; Female; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Manganese; Molybdenum; Nutritional Requirements; Phenylalanine; Selenium; Threonine; Tyrosine; Vitamins; Zinc | 1970 |
Amino acid interactions in chick nutrition. 2. Interrelationships between leucine, isoleucine and valine.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Arginine; Body Weight; Chickens; Female; Glycine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Tyrosine; Valine | 1970 |
Plasma amino acid imbalance in patients with chronic renal failure on intermittent dialysis.
Topics: Amino Acids; Creatinine; Diet; Humans; Kidney Failure, Chronic; Nitrogen; Phenylalanine; Renal Dialysis; Transferrin; Tyrosine; Uremia | 1970 |
[Pterin chemistry. 28. Hydroxylation of phenylalanine to tyrosine using tetrahydropterin under physiologic conditions].
Topics: Chelating Agents; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Iron; Phenylalanine; Pterins; Tyrosine | 1970 |
[Pterin chemistry. 29. Hydroxylation of phenyl residues of phenylalanylpeptides using tetrahydropterin under physiologic conditions].
Topics: Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Peptides; Phenylalanine; Pterins; Tyrosine | 1970 |
Dietary treatment of tyrosinosis.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Diet Therapy; Dietary Proteins; Female; Food Analysis; Formularies as Topic; Humans; Phenylalanine; Tyrosine | 1970 |
Effects of denaturing agents on the phenylalanyl circular dichroism bands of horseradish peroxidase isoenzymes and apoisoenzymes.
Topics: Amides; Detergents; Guanidines; Hydrogen-Ion Concentration; Isoenzymes; Peroxidases; Phenylalanine; Plants; Protein Denaturation; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine; Ultraviolet Rays | 1970 |
Phenyketonuria. Evaluation of early treatment.
Topics: Age Factors; Body Height; Body Weight; Diet Therapy; Electroencephalography; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1970 |
Effect of alpha-methyltyrosine on stress-induced changes in seizure susceptibility.
Topics: Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Disulfiram; Male; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Phenylalanine; Reserpine; Seizures; Stress, Physiological; Tetrabenazine; Time Factors; Tyrosine | 1970 |
Phenylalanine uptake and phenylalanine-binding material in Comamonas sp. (ATCC 11299a).
Topics: Asparagine; Bacteria; Biological Transport; Carbon Isotopes; Depression, Chemical; Dialysis; Dinitrophenols; Enzyme Induction; Ethylmaleimide; Filtration; Kinetics; Malonates; Osmolar Concentration; Phenylalanine; Protein Biosynthesis; Tryptophan; Tyrosine | 1970 |
[Phenylalanine tolerance tests].
Topics: Age Factors; Amino Acid Metabolism, Inborn Errors; Child; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1970 |
Alternative allosteric effects exerted by end products upon a two-substrate enzyme in Rhodomicrobium vannielii.
Topics: Aldehyde-Lyases; Bacteria; Chemical Phenomena; Chemistry; Enzyme Activation; Heptoses; Kinetics; Phenylalanine; Phosphoric Acids; Pyruvates; Tetroses; Tryptophan; Tyrosine | 1970 |
The C-terminal antigenic site of sperm-whale myoglobin: the immunological activities of synthetic peptides related to the C-terminus of myoglobin.
Topics: Animals; Antigen-Antibody Reactions; Antigens; Binding Sites; Cetacea; Chromatography, Paper; Electrophoresis; Immune Sera; Myoglobin; Peptides; Phenylalanine; Tyrosine | 1970 |
Amino acid metabolism in hereditary fructosemia.
Topics: Amino Acids; Blood Glucose; Carbohydrate Metabolism, Inborn Errors; Chromatography, Paper; Female; Fructose; Fructose-Bisphosphate Aldolase; Humans; Infant; Infant, Newborn; Liver; Male; Phenylalanine; Tyrosine | 1970 |
Circadian ythm of human urinary amino acid excretion in fed and fasted states.
Topics: 17-Hydroxycorticosteroids; Adult; Alanine; Amino Acids; Asparagine; Circadian Rhythm; Cystinuria; Fasting; Feeding Behavior; Glutamates; Glutamine; Glycine; Humans; Male; Middle Aged; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1970 |
Two siblings of hyperphenylalaninemia: suggestion to a genetic variant of phenylketonuria.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Humans; Infant; Intellectual Disability; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1970 |
The effect of enzyme concentration, ionic strength, and temperature on the stoichiometry of the phenylalanine hydroxylase reaction.
Topics: Kinetics; Mixed Function Oxygenases; Osmolar Concentration; Phenylalanine; Pteridines; Temperature; Tyrosine | 1970 |
[Chorismate mutase from Claviceps. I. Properties of chorismate mutase from different strains of Claviceps].
Topics: Ascomycota; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclohexanecarboxylic Acids; Electrophoresis; Enzyme Activation; Hydrogen-Ion Concentration; Isomerases; Kinetics; Molecular Weight; Phenylalanine; Phosphotransferases; Stereoisomerism; Tryptophan; Tyrosine | 1970 |
From the Clinical Conference St. Louis Children's Hospital. Phenylketonuria. Diagnostic and therapeutic dilemma.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diet Therapy; Female; Humans; Infant; Intellectual Disability; Phenylalanine; Phenylketonurias; Transaminases; Tryptophan; Tyrosine | 1970 |
Taenia crassiceps: uptake of basic and aromatic amino acids and imino acids by larvae.
Topics: Amino Acids; Animals; Arginine; Biological Transport, Active; Carbon Isotopes; Histidine; Imines; Kinetics; Larva; Lysine; Ornithine; Phenylalanine; Proline; Taenia; Tritium; Tyrosine | 1970 |
[Evolution of endopeptidases. XI. A protease with chymotryptic specificity from the gastric juice of Sepia officinalis (cuttlefish)].
Topics: Animals; Arginine; Bromides; Chromatography, Ion Exchange; Chymotrypsin; Electrophoresis; Esters; Gastric Juice; Insulin; Molecular Weight; Mollusca; Naphthaleneacetic Acids; Peptide Hydrolases; Peptides; Phenylalanine; Phosphates; Sodium Chloride; Tyrosine | 1970 |
[Tyrosine metabolism in insects. XVIII. Activity of phenylalanine-4-hydroxylase and the N-acetyldopamine glucoside-forming system in vivo during the development of Calliphora erythrocephala Meigen].
Topics: Animals; Carbon Isotopes; Chromatography, Paper; Dopamine; Glycosides; Insecta; Larva; Metamorphosis, Biological; Mixed Function Oxygenases; Phenylalanine; Tyrosine | 1970 |
[Chorismate mutase from Claviceps. II. Activation and inhibition by analogues of the effectors tryptophan, phenylalanine and tyrosine].
Topics: Ascomycota; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cyclohexanecarboxylic Acids; Cysteine; Enzyme Activation; Histidine; Kinetics; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1970 |
Benzimidazole-5(6)-alanine and related compounds. 1. Synthesis of amino acids as inhibitors of norepinephrine biosynthesis.
Topics: Alanine; Amino Acids; Benzimidazoles; Methods; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Tyrosine | 1970 |
Changes in the concentration of specific amino acids in the serum of experimentally malnourished pigs.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Dietary Proteins; Female; Gluconeogenesis; Glycine; Histidine; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Proline; Protein Deficiency; Serine; Swine; Threonine; Tyrosine; Valine | 1970 |
Evidence from proton magnetic resonance data for the stacking of aromatic amino acids in lysine-vasopressin: comparison with oxytocin derivatives and related dipeptides.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Lysine; Magnetic Resonance Spectroscopy; Oxytocin; Phenylalanine; Tyrosine; Vasopressins | 1970 |
Chromosomal control of foot pad development in Sarcophaga bullata. II. Cuticle formation and tanning.
Topics: Animals; Carbon Isotopes; Chitin; Chromosomes; Culture Techniques; Densitometry; Diptera; DNA; Glucose; Leucine; Male; Metamorphosis, Biological; Phenylalanine; Pigmentation; Polysaccharides; Protein Biosynthesis; Skin; Spectrophotometry; Thymidine; Tritium; Tyrosine | 1970 |
Effect of carbobenzoxy derivatives of amino acids on glutamine synthesis and gamma-glutamyl transfer.
Topics: Acyltransferases; Alanine; Amino Acids; Animals; Asparagine; Brain; Chemical Phenomena; Chemistry; Formates; Glutamine; Glycine; Kinetics; Ligases; Liver; Lysine; Phenylalanine; Rats; Sheep; Tyrosine | 1970 |
In vitro methylation of yeast serine transfer ribonucleic acid.
Topics: Adenine; Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography; Chromatography, DEAE-Cellulose; Chromatography, Gel; Kinetics; Methylation; Phenylalanine; Rats; Ribonucleases; RNA, Transfer; Saccharomyces; Serine; Transferases; Tritium; Tyrosine; Valine | 1970 |
Effects of excess dietary phenylalanine on composition of cerebral lipids.
Topics: Animals; Body Weight; Brain; Brain Chemistry; Cholesterol; Diet; Glycolipids; Humans; Lipids; Male; Myelin Sheath; Organ Size; Phenylalanine; Phenylketonurias; Phospholipids; Plasmalogens; Rats; Stereoisomerism; Tyrosine | 1970 |
Amino acid interactions in chick nutrition. 3. Interdependence in amino acid requirements.
Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Arginine; Chickens; Glycine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Requirements; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1970 |
Determination of pico-mole quantities of gamma-amino-butyric acid (GABA) and serotonin.
Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Arginine; Aspartic Acid; Autoradiography; Brain Chemistry; Carbon Isotopes; Cerebellum; Chromatography; Cysteine; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methods; Microchemistry; Phenylalanine; Proline; Radionuclide Imaging; Rats; Serine; Serotonin; Threonine; Tyrosine; Valine | 1970 |
Effects of amino acid analogs on growth and toxin of Staphylococcus aureus.
Topics: Amino Acids; Cysteine; Ethionine; Fluorine; Methionine; Nitriles; Phenylalanine; Staphylococcus; Tyrosine | 1970 |
Chorismate mutase from Euglena gracilis. Purification and regulatory properties.
Topics: Acids; Benzene Derivatives; Chromatography; Cyclohexanecarboxylic Acids; Electrophoresis; Enzyme Activation; Euglena; Hydrogen-Ion Concentration; Isomerases; Molecular Weight; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1970 |
Effect of epinephrine and its precursors on activity of proteolytic enzymes.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Enzyme Activation; Epinephrine; Liver; Muscles; Peptide Hydrolases; Phenylalanine; Threonine; Tryptophan; Tyrosine | 1970 |
The middle ultraviolet spectra of proteins. I. Studies on model compounds.
Topics: Amino Acids; Benzene; Cresols; Cysteine; Histidine; Hydrogen-Ion Concentration; Imidazoles; Indoles; Methionine; Phenols; Phenylalanine; Proteins; Spectrophotometry; Spectrum Analysis; Toluene; Tryptophan; Tyrosine; Ultraviolet Rays | 1970 |
Response of adult rats to low dietary levels of essential amino acids.
Topics: Amino Acids; Animals; Body Weight; Cystine; Deficiency Diseases; Diet; Dietary Proteins; Female; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1970 |
Distribution of ammonia-lyases in organelles of castor bean endosperm.
Topics: Glucosephosphate Dehydrogenase; Histidine; Lyases; Mitochondria; Organoids; Phenylalanine; Plants, Toxic; Ricinus; Stereoisomerism; Succinate Dehydrogenase; Tyrosine | 1970 |
Aromatic amino acid hydroxylase inhibitors. 1. Halogenated phenylalanines.
Topics: Chemical Phenomena; Chemistry; Halogens; Iodine; Methylation; Mixed Function Oxygenases; Phenylalanine; Tyrosine | 1970 |
[Properties of a chymotrypsin-like N-acylamino acid esterase of rat's serum].
Topics: Amino Acids; Animals; Arginine; Chemical Precipitation; Chromatography, Gel; Chymotrypsin; Electrophoresis; Esterases; Esters; Phenylalanine; Rats; Tyrosine | 1970 |
Atypical phenylketonuria in a family with a phenylketonuric mother.
Topics: Adult; Alleles; Child; Female; Genes, Regulator; Heterozygote; Humans; Infant, Newborn; Male; Microcephaly; Milk, Human; Mixed Function Oxygenases; Phenotype; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1970 |
Influence of time of fast on concentrations of free amino acids in plasma and total amino acids in liver protein of young swine.
Topics: Age Factors; Amino Acids; Animal Feed; Animals; Arginine; Chromatography, Ion Exchange; Cystine; Dietary Proteins; Fasting; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Swine; Threonine; Time Factors; Tyrosine; Valine | 1970 |
Fluorescent substances in protein hydrolyzates. I. Acid "hydrolyzates" of individual amino acids.
Topics: Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Paper; Fluorescence; Fluorometry; Histidine; Hydrochloric Acid; Hydrogen-Ion Concentration; Phenylalanine; Protein Hydrolysates; Tryptophan; Tyrosine | 1970 |
Biogenesis of rosmarinic acid in Mentha.
Topics: Carbon Isotopes; Cinnamates; Coumarins; Dihydroxyphenylalanine; Lactates; Phenylalanine; Plants; Tyrosine | 1970 |
A comparison of the analgesia produced by morphine and the sympathomimetic drugs.
Topics: Amphetamine; Analgesia; Animals; Iproniazid; Mice; Morphine; Phenylalanine; Reaction Time; Reserpine; Serotonin; Sympathomimetics; Tyrosine | 1970 |
[The action of peptidase beta from brewer's yeast on the B chain of oxidized insulin].
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chromatography, Paper; Chymotrypsin; Electrophoresis; Insulin; Leucine; Peptide Hydrolases; Phenylalanine; Saccharomyces; Tyrosine | 1970 |
Lack of hydroxylation-induced migration with 4-iodophenylalanine.
Topics: Amino Acids; Animals; Autoradiography; Carbon Isotopes; Chromatography, Paper; Iodine; Iodine Isotopes; Liver; Mixed Function Oxygenases; Monoiodotyrosine; Phenylalanine; Rats; Tyrosine | 1970 |
Hydroxylations of aromatic amino acids mediated by a tetrahydropterin.
Topics: Amino Acids; Autoanalysis; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Fluorometry; Iron; Phenylalanine; Pterins; Tritium; Tyrosine | 1970 |
[Properties of phospho-2-oxo-3-deoxyheptonate aldolase from Claviceps SD 58].
Topics: Aldehyde-Lyases; Ascomycota; Chloromercuribenzoates; Chromatography, Gel; Hot Temperature; Hydrogen-Ion Concentration; Keto Acids; Kinetics; Molecular Weight; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
The affinity of flavin semiquinones for certain aromatic compounds and disulfides.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Flavin Mononucleotide; Glutathione; Methods; Nicotinic Acids; Oxidation-Reduction; Phenylalanine; Picolinic Acids; Pyridines; Quinones; Riboflavin; Serotonin; Sulfides; Tryptophan; Tyrosine | 1970 |
In vivo formation of tyrosine from phenylalanine in brain.
Topics: Animals; Brain; Carbon Isotopes; Cerebral Ventricles; Chromatography; Injections; Male; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Rats; Tyrosine | 1970 |
Acid catalysis of the formaldehyde condensation reaction for sensitive histochemical demonstration of trptamines and 3-methoxylated phenylethylamines. 1. Modelexperiments.
Topics: Amphetamine; Catalysis; Catecholamines; Chemical Phenomena; Chemistry; Epinephrine; Fluorescence; Fluorometry; Formaldehyde; Gases; Histamine; Hydrochloric Acid; Indoles; Isoquinolines; Melatonin; Models, Chemical; Norepinephrine; Normetanephrine; Phenethylamines; Phenylalanine; Pyridines; Tryptamines; Tyramine; Tyrosine | 1970 |
Lysine uptake in cultured Trypanosoma cruzi: interactions of competitive inhibitors.
Topics: Alanine; Animals; Biological Transport; Cysteine; Glycine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Trypanosoma; Tyrosine; Valine | 1970 |
Atypical phenylketonuria. An approach to diagnosis and management.
Topics: Biological Assay; Child; Chromatography; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1970 |
Unrecognized maternal biochemical disease: an uncommon cause of mental retardation in children.
Topics: Child; Cystinuria; Female; Glycine; Humans; Infant, Newborn; Intellectual Disability; Lysine; Metabolic Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Proline; Tyrosine | 1970 |
Molecular conformation of L-dopa.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Dipeptides; Dopamine; Glycine; Hydrogen; Isomerism; Norepinephrine; Peptides; Phenylalanine; Rotation; Threonine; Tyrosine; X-Ray Diffraction | 1970 |
[Experiences with a new amino acid analyzer for a rapid analysis].
Topics: Amino Acids; Autoanalysis; Homocystine; Homocystinuria; Humans; Infant, Newborn; Infant, Premature, Diseases; Isoleucine; Leucine; Maple Syrup Urine Disease; Metabolic Diseases; Methionine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1970 |
1-amino-2-phenylethane 1-phosphonic acid: a specific competitive inhibitor of phenylalanyl-tRNA synthetase.
Topics: Amino Acyl-tRNA Synthetases; Kinetics; Leucine; Organophosphonates; Phenylalanine; Plants; Threonine; Tyrosine; Valine | 1970 |
The susceptibility of N-acetyl-S-alkyl- and N-acetyl-S-aryl-cysteine ethyl esters to chymotryptic hydrolysis.
Topics: Acetates; Alkanes; Amines; Animals; Benzene Derivatives; Butylamines; Caproates; Cattle; Chymotrypsin; Cysteine; Esters; Kinetics; Methionine; Pancreas; Phenylalanine; Tryptophan; Tyrosine; Valerates | 1970 |
Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.
Topics: Amides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Lasers; Muramidase; Peptides; Phenylalanine; Protein Denaturation; Ribonucleases; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine | 1970 |
A learning impairment associated with induced phenylketonuria.
Topics: Age Factors; Amino Acids; Animals; Behavior, Animal; Body Weight; Chromatography, Thin Layer; Diet; Female; Humans; Learning Disabilities; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pregnancy; Pregnancy, Animal; Rats; Tyrosine | 1970 |
Cerebral lipid metabolism in experimental hyperphenylalaninaemia: incorporation of 14C-labelled glucose into total lipids.
Topics: Animals; Animals, Newborn; Brain; Carbon Isotopes; Disease Models, Animal; Glucose; Humans; In Vitro Techniques; Lipids; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Rats; Tyrosine | 1970 |
The properties of bovine growth hormone. IV. Circular dichroism of native and iodinated molecules.
Topics: Animals; Carbonates; Cattle; Chemical Phenomena; Chemistry; Circular Dichroism; Growth Hormone; Hydrogen-Ion Concentration; Iodine; Models, Chemical; Phenylalanine; Piperazines; Tryptophan; Tyrosine; Ultraviolet Rays; Urea | 1970 |
Influence of mode and duration of phenylalanine administration on biochemical parameters in rats of various ages.
Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Brain Chemistry; Corticosterone; Diet; Humans; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Serotonin; Tryptophan Hydroxylase; Tyrosine | 1970 |
L-(U-14C) tyrosine metabolism of the perfused cat brain with high plasma phenylalanine or without plasma tyrosine.
Topics: Amino Acids; Animals; Autoanalysis; Brain; Carbon Isotopes; Cats; Chromatography, Ion Exchange; Perfusion; Phenylalanine; Tyrosine; Uracil | 1970 |
Neonatal hyperphenylalaninemia: a differential diagnosis.
Topics: Amino Acid Metabolism, Inborn Errors; Diagnosis, Differential; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Infant, Premature; Male; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Prognosis; Transaminases; Tyrosine | 1970 |
L-phenylalanine and L-tyrosine requirements of the growing rat.
Topics: Animals; Diet; Nutritional Requirements; Phenylalanine; Rats; Tyrosine | 1971 |
Effect of essential amino acid restriction on the growth of female C57BL mice and their implanted BW10232 adenocarcinomas.
Topics: Adenocarcinoma; Amino Acids; Animals; Body Weight; Deficiency Diseases; Female; Isoleucine; Leucine; Lysine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Rats; Threonine; Transplantation, Homologous; Tryptophan; Tyrosine; Valine | 1971 |
Urinary amino acid excretion in patients with scleroderma.
Topics: Arginine; Aspartic Acid; Chelating Agents; Female; Glutamates; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Phenylalanine; Renal Aminoacidurias; Scleroderma, Systemic; Threonine; Tyrosine; Valine | 1971 |
[Evaluation of the activity of a phenylketonuria detection center. Analysis of the results of 500,000 tests].
Topics: Adolescent; Adult; Child; Child, Preschool; Chromatography, Paper; Female; Humans; Infant; Infant, Newborn; Intellectual Disability; Mass Screening; Phenylalanine; Phenylketonurias; Preventive Health Services; Tyrosine | 1971 |
Gas chromatographic analysis of N-acetyldopamine and its potential metabolic precursors.
Topics: Animals; Chromatography, Gas; Cyprinidae; Dihydroxyphenylalanine; Dopamine; Mass Spectrometry; Methods; Phenylalanine; Quinones; Silicon; Tyramine; Tyrosine | 1971 |
Fluorescence quenching due to mercuric ion interaction with aromatic amino acids and proteins.
Topics: Benzoates; Chemical Phenomena; Chemistry; Chymotrypsin; Energy Transfer; Enzyme Precursors; Fluorescence; Indoles; Lactoglobulins; Mercury; Nitrates; Ovalbumin; Phenylalanine; Serum Albumin; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Some properties of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase isoenzymes from mutant strains of Neurospora crassa.
Topics: Aldehyde-Lyases; Alleles; Chromatography, Gel; Genetics, Microbial; Heptoses; Isoenzymes; Molecular Weight; Mutation; Neurospora; Phenylalanine; Polymers; Tryptophan; Tyrosine | 1971 |
[The dependence of the photosensitivity of animo acids on their micro-environment].
Topics: Amino Acids; Cystine; Phenylalanine; Photosensitivity Disorders; Polymers; Radiation Effects; Spectrophotometry; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Some aspects of uptake of non-metabolites in slices of mouse brain.
Topics: Amines; Animals; Arginine; Biological Transport, Active; Body Fluids; Brain; Carbon Isotopes; Creatine; Cyanides; Depression, Chemical; Dinitrophenols; Extracellular Space; In Vitro Techniques; Inulin; Lysine; Mannitol; Mice; Phenylalanine; Phosphocreatine; Polyamines; Spermine; Stimulation, Chemical; Sulfates; Sulfur Isotopes; Tyrosine; Urea | 1971 |
The fluorescence quenching of aromatic amino acid and flavin portions of flavinyl peptides.
Topics: Flavins; Fluorescence; Peptides; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1971 |
Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. V. Determination of pre-steady state kinetic parameters for specific substrate esters by stopped flow techniques.
Topics: Acridines; Amides; Arginine; Chemical Phenomena; Chemistry; Chymotrypsin; Esters; Ethanol; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Leucine; Methanol; Phenylalanine; Protein Binding; Spectrophotometry; Tryptophan; Tyrosine | 1971 |
Proton magnetic resonance studies of oligopeptides containing aromatic residues.
Topics: Deuterium; Dimethyl Sulfoxide; Dipeptides; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptides; Phenylalanine; Protein Denaturation; Proteins; Protons; Tryptophan; Tyrosine | 1971 |
Calcium binding by the troponin complex, and the purification and properties of troponin A.
Topics: Amino Acids; Animals; Binding Sites; Calcium; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Hydrogen-Ion Concentration; Molecular Weight; Muscle Proteins; Muscles; Myofibrils; Osmolar Concentration; Phenylalanine; Protein Binding; Rabbits; Tyrosine | 1971 |
Nutrient media for plant-parasitic nematodes. II. Amino acid requirements of Aphelenchoides sp.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Carbon Isotopes; Chromatography, Thin Layer; Culture Media; Fungi; Germ-Free Life; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Nematoda; Nutritional Requirements; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1971 |
Phenylalanine transport in utero.
Topics: Amniotic Fluid; Autoradiography; Biological Transport, Active; Erythrocytes; Female; Fetus; Heart Rate; Humans; Kidney Tubules; Liver; Macrophages; Maternal-Fetal Exchange; Perfusion; Phenylalanine; Pregnancy; Trophoblasts; Tyrosine; Uterus | 1971 |
Placental transfer of amino acids in the rat. II. Aromatic amino acids.
Topics: Animals; Biological Transport, Active; Female; Fetus; Maternal-Fetal Exchange; Phenylalanine; Placenta; Pregnancy; Rats; Time Factors; Tryptophan; Tyrosine | 1971 |
Amino acid metabolism in the isolated perfused rat liver.
Topics: Alanine; Amino Acids; Ammonia; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; In Vitro Techniques; Liver; Lysine; Male; Methionine; Nitrogen Isotopes; Perfusion; Phenylalanine; Proline; Rats; Serine; Threonine; Tryptophan; Tyrosine; Urea | 1971 |
The entry of amino acids into the myocardium of the growing rat in vivo.
Topics: Amino Acids; Animals; Aspartic Acid; Diffusion; Glycine; Heart; Histidine; Isoleucine; Leucine; Lysine; Methionine; Myocardium; Phenylalanine; Protein Binding; Protein Biosynthesis; Rats; Serine; Taurine; Tryptophan; Tyrosine; Valine | 1971 |
The subunit structure of formyltetrahydrofolate synthetase.
Topics: Adenosine Triphosphate; Ammonium Chloride; Carbohydrates; Chemical Phenomena; Chemistry; Chlorides; Chromatography, Gel; Clostridium; Drug Stability; Enzyme Activation; Folic Acid; Formates; Guanidines; Hydrogen-Ion Concentration; Ligases; Macromolecular Substances; Magnesium; Mercaptoethanol; Metals; Molecular Weight; Optical Rotatory Dispersion; Phenylalanine; Potassium; Rubidium; Spectrophotometry; Tromethamine; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 1971 |
Effects of excess phenylalanine on in vitro and in vivo RNA and protein synthesis and polyribosome levels in brains of mice.
Topics: Age Factors; Animals; Brain; Glutamates; Injections, Intraperitoneal; Leucine; Liver; Mice; Nerve Tissue Proteins; Phenylalanine; Ribosomes; RNA; Tryptophan; Tyrosine | 1971 |
[A new method of detection of heterozygotes in phenylpyruvic oligophrenia].
Topics: Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Statistics as Topic; Tyrosine | 1971 |
Response of oxidative phosphorylation in rat liver to prolonged protein depletion.
Topics: Animals; Arginine; Caseins; Cystine; Dietary Proteins; Glutamates; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Oxidative Phosphorylation; Oxygen Consumption; Phenylalanine; Phosphates; Protein Deficiency; Rats; Succinate Dehydrogenase; Succinates; Threonine; Time Factors; Tyrosine; Valine | 1971 |
Iodine modification of E. coli tRNA Phe : reversible modification of 2-methylthio-N 6 -isopentenyladenosine and lack of disulfide formation.
Topics: Chemical Phenomena; Chemical Precipitation; Chemistry; Crystallography; Filtration; Iodides; Iodine Isotopes; Kinetics; Molecular Biology; Nucleosides; Oxidation-Reduction; Peptides; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry; Sulfides; Thiosulfates; Tyrosine; Ultraviolet Rays; Uridine; Valine | 1971 |
Cutaneous manifestations of disorders of metabolism of phenylalanine-tyrosine.
Topics: Albinism; Amino Acid Metabolism, Inborn Errors; Humans; Phenylalanine; Pigmentation Disorders; Skin Manifestations; Tyrosine | 1971 |
Essential amino acids in the culture of Leishmania tarentolae.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Culture Media; Glucose; Glutamates; Glycine; Histidine; Leishmania; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1971 |
Structural genes for DAHP synthase isoenzymes in Neurospora crassa.
Topics: Aldehyde-Lyases; Binding Sites; Feedback; Genes; Genetic Complementation Test; Heptoses; Isoenzymes; Mutation; Neurospora; Phenylalanine; Tetroses; Tryptophan; Tyrosine | 1971 |
Molecular transport. I. In vivo studies of transport mutants of Neurospora crassa with altered amino acid competition patterns.
Topics: Alanine; Arginine; Aspartic Acid; Biological Transport, Active; Carbon Isotopes; Chromatography, Paper; Crosses, Genetic; Genetics, Microbial; Histidine; Isoleucine; Kinetics; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Serine; Stereoisomerism; Threonine; Tyrosine; Valine | 1971 |
Circular dichroism studies on human chorionic somatomammotropin.
Topics: Acetates; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Circular Dichroism; Female; Glycine; Guanidines; Humans; Hydrochloric Acid; Hydrogen-Ion Concentration; Molecular Weight; Osmotic Pressure; Phenylalanine; Placental Hormones; Placental Lactogen; Pregnancy; Protein Denaturation; Sodium Hydroxide; Tromethamine; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Interrelationships between level of amino acids in plasma and tissues during starvation.
Topics: Amino Acids; Animals; Chromatography, Ion Exchange; Intestine, Small; Isoleucine; Kidney; Leucine; Liver; Male; Methionine; Muscles; Myocardium; Phenylalanine; Rats; Starvation; Tyrosine; Valine | 1971 |
The relationship of adrenal glucocorticoids to transaminase activity and gluconeogenesis in the intact rat.
Topics: Adrenalectomy; Alanine; Animals; Aspartate Aminotransferases; Aspartic Acid; Biological Transport; Blood Glucose; Carbon Isotopes; Cell Membrane Permeability; Chromatography, Ion Exchange; Extracellular Space; Fasting; Glucocorticoids; Gluconeogenesis; Glucose; Glutamates; Glycine; Isoleucine; Kinetics; Liver; Methionine; Phenylalanine; Proline; Rats; Transaminases; Tritium; Tyrosine; Valine; Water | 1971 |
L-dopa: disaggregation of brain polysomes and elevation of brain tryptophan.
Topics: Animals; Brain; Brain Chemistry; Dihydroxyphenylalanine; Phenylalanine; Rats; Ribosomes; Time Factors; Tryptophan; Tyrosine | 1971 |
A rapid procedure for the determination of phenylalanine and tyrosine from blood filter paper specimens.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Autoanalysis; Chromatography, Ion Exchange; Horses; Hot Temperature; Humans; Paper; Phenylalanine; Phenylketonurias; Tyrosine | 1971 |
Simplified thin layer chromatography screening test for detection of important hyperaminoacidemias.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Chromatography, Thin Layer; Humans; Isoleucine; Leucine; Mass Screening; Methionine; Methods; Phenylalanine; Tyrosine; Valine | 1971 |
Column chromatographic analysis of tryptophan with the basic amino acids.
Topics: Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Fasting; Female; Humans; Male; Methods; Phenylalanine; Tryptophan; Tyrosine | 1971 |
Dietary regulation of plasma insulin and growth hormone concentrations in sheep.
Topics: Acetates; Animal Feed; Animals; Blood Glucose; Butyrates; Diet; Dietary Proteins; Fasting; Glucose; Growth Hormone; Insulin; Intestinal Mucosa; Isoleucine; Male; Nitrogen; Phenylalanine; Propionates; Sheep; Tyrosine; Valine | 1971 |
Mechanism of suppression in Drosophila: a change in tyrosine transfer RNA.
Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography; Drosophila; Genes, Recessive; Genetic Code; Leucine; Mutation; Phenylalanine; RNA, Transfer; Serine; Sex Chromosomes; Suppression, Genetic; Tritium; Tyrosine | 1971 |
Discriminant analysis for detection of phenylketonuric heterozygotes.
Topics: Adult; Female; Heterozygote; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Statistics as Topic; Tyrosine | 1971 |
Polyribosome disaggregation and cell-free protein synthesis in preparations from cerebral cortex of hyperphenylalaninemic rats.
Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Cell Aggregation; Cell-Free System; Cerebral Cortex; In Vitro Techniques; Injections, Intraperitoneal; Liver; Microsomes; Nerve Tissue Proteins; Phenylalanine; Protein Biosynthesis; Rats; Ribosomes; Serotonin; Tryptophan; Tyrosine | 1971 |
[Regulation of the 1st stage of the pathway for the biosynthesis of aromatic components in Saccharomyces cerevisae].
Topics: Cell-Free System; Cobalt; Diploidy; Fructose-Bisphosphate Aldolase; Genetics, Microbial; Models, Biological; Mutation; Phenotype; Phenylalanine; Protein Denaturation; Saccharomyces; Stimulation, Chemical; Tyrosine | 1967 |
Radiolysis in aqueous solution of aromatic amino acids.
Topics: Phenylalanine; Radiation Effects; Radiochemistry; Tyrosine | 1967 |
[Demonstration of enzymes for the biosynthesis of aromatic amino acids in Claviceps paspali].
Topics: Ascomycota; Ligases; Oxidoreductases; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1967 |
Gamma-glutamyl-phenylalanine and gamma-l-glutamyl-l-tyrosine from seeds of Aubrietia deltoidea DC.
Topics: Amino Acids; Chromatography, Paper; Glutamates; Phenylalanine; Seeds; Tyrosine | 1967 |
Aromatic amino acid biosynthesis and para-fluorophenylalanine resistance in Aspergillus nidulans.
Topics: Aspergillus; Drug Resistance, Microbial; Phenylalanine; Tyrosine | 1967 |
[DOPA-DOPP-transaminases of rat brain in vitro].
Topics: Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Glutamates; In Vitro Techniques; Kinetics; Phenylalanine; Phenylpyruvic Acids; Rats; Transaminases; Tyrosine | 1967 |
Influence of amino acids and organic antimetabolites on growth and biosynthesis of the chemoautotroph Thiobacillus neapolitanus strain C.
Topics: Amino Acids; Antimetabolites; Bacterial Proteins; Carbon Dioxide; Carbon Isotopes; Chloramphenicol; Chromatography; Glutamates; Glycine; Methionine; Phenylalanine; Proline; Thiobacillus; Thiosulfates; Tyrosine | 1967 |
Phenylketonuria, a family study. Borderline intelligence in two siblings with mentally retarded children.
Topics: Adolescent; Adult; Female; Genotype; Humans; Intellectual Disability; Male; Pedigree; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
[On the biosynthesis of aromatic amino acids in Lactobacillus arabinosus].
Topics: Cyclohexanecarboxylic Acids; Lactobacillus; Ligases; ortho-Aminobenzoates; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1967 |
[Hyperaminoaciduria in children suffering from progressive muscular dystrophy].
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Arginine; Aspartic Acid; Child; Child, Preschool; Creatine; Creatinine; Female; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Muscular Dystrophies; Nitrogen; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[On some problems of paper chromatographic amino acid analysis of natural materials].
Topics: Amino Acids; Chromatography, Paper; Cystine; Edible Grain; Formates; Histidine; Medicago sativa; Methionine; Methods; Oxidation-Reduction; Phenylalanine; Proteins; Triticum; Tryptophan; Tyrosine | 1967 |
[Quantitative paper chromatography amino acid determination. Stanardization of the procedure and method of testing of new paper types].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography, Paper; Cysteine; Glutamates; Glycine; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Methods; Paper; Phenylalanine; Serine; Spectrum Analysis; Sulfones; Threonine; Tyrosine; Ultraviolet Rays; Valine | 1967 |
[Paper chromatographic amino acids analysis of natural compounds].
Topics: Amino Acids; Arginine; Chemistry Techniques, Analytical; Chromatography, Paper; Cystine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Oxidation-Reduction; Phenylalanine; Proteins; Solvents; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Essential amino acids for milk protein synthesis in the in vitro secretory cell and stimulation by elevated levels.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Caseins; Cattle; Culture Techniques; Cystine; Female; Glutamine; Histidine; Isoleucine; Lactation; Lactoglobulins; Leucine; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Pregnancy; Rats; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Ammonia production by rumen microbes in vitro.
Topics: Alanine; Amino Acids; Ammonia; Animals; Arginine; Asparagine; Aspartic Acid; Cysteine; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Rumen; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
[Phenylalanine and tyrosine in albino rat brain in the normal state and in experimental phenylketonuria].
Topics: Animals; Brain; Humans; Oxidoreductases; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pyruvates; Rats; Tyrosine | 1967 |
Studies on progressive muscular dystrophy. IV. Effects of original amino acids mixture on progressive muscular dystrophy.
Topics: Adenosine Triphosphate; Adolescent; Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Blood Proteins; Child; Deficiency Diseases; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Methionine; Muscles; Muscular Dystrophies; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Phenylketonuria: evaluation of therapy and verification of diagnosis.
Topics: Blood Protein Electrophoresis; Blood Proteins; Body Height; Body Weight; Child, Preschool; Deficiency Diseases; Diet Therapy; Female; Head; Humans; Infant; Intelligence; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
Electroencephalographic effects of L-phenylalanine in the cat.
Topics: Animals; Cats; Cerebral Cortex; Electroencephalography; Light; Phenylalanine; Tyrosine | 1968 |
Phenylalanine and tyrosine in vegetables and fruits.
Topics: Dietetics; Food Analysis; Fruit; Humans; Phenylalanine; Proteins; Tyrosine; Vegetables | 1968 |
Reaction of beta-propiolactone with amino acids and its specificity for methionine.
Topics: Amino Acids; Autoanalysis; Chemical Phenomena; Chemistry; Cold Temperature; Cystine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Lactones; Leucine; Lysine; Methionine; Phenylalanine; Proline; Tyrosine | 1968 |
Studies on polynucleotides. LXXXII. Yeast phenylalanine transfer ribonucleic acid: partial digestion with ribonuclease T-1 and derivation of the total primary structure.
Topics: Cellulose; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Genetic Code; Nucleotides; Phenylalanine; Ribonucleases; RNA, Transfer; Tyrosine | 1968 |
The influence of high phenylalanine and tyrosine on the concentrations of essential amino acids in brain.
Topics: Amino Acids; Animals; Animals, Newborn; Brain Chemistry; Centrifugation; Chromatography; Diet; Fluorometry; Injections, Intraperitoneal; Male; Phenylalanine; Rats; Spectrophotometry; Tyrosine | 1968 |
Aromatic biosynthesis in yeast. II. Feedback inhibition and repression of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthase.
Topics: Aldehyde-Lyases; Binding Sites; Chemical Precipitation; Enzyme Repression; Feedback; Isoenzymes; Phenylalanine; Saccharomyces; Tryptophan; Tyrosine | 1968 |
Pulse radiolysis of phenylalanine and tyrosine.
Topics: Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Radiation Effects; Radiochemistry; Spectrum Analysis; Tyrosine | 1968 |
Biochemical and behavioral effects of a commercial "low phenylalanine" diet in growing rats.
Topics: Animals; Animals, Newborn; Avoidance Learning; Brain; Conditioning, Operant; Diet; Female; Glutamine; Growth; Ligases; Liver; Mixed Function Oxygenases; Phenylalanine; Pregnancy; Rats; Tyrosine | 1968 |
Transient tyrosinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Humans; Phenylalanine; Phenylketonurias; Terminology as Topic; Tyrosine | 1968 |
Phenylketonuria. Mass screening of newborns in Ireland.
Topics: Chromatography; Humans; Infant, Newborn; Infant, Newborn, Diseases; Ireland; Mass Screening; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
The biosynthesis of phenylalanine and tyrosine in the pea (Pisum sativum): chorismate mutase.
Topics: Cellulose; Chromatography, Ion Exchange; Feedback; Phenylalanine; Phosphotransferases; Plants; Tryptophan; Tyrosine | 1968 |
Long-term dietary treatment of tyrosinosis.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Body Weight; Chromatography, Ion Exchange; Chromatography, Paper; Diet Therapy; Glucose; Humans; Infant; Kidney Tubules; Liver; Male; Oxidoreductases; Phenylalanine; Phosphates; Pyruvates; Tyrosine | 1968 |
Transient hyperphenylalaninemia.
Topics: Child, Preschool; Diagnosis, Differential; Diet Therapy; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
Histochemical differentiation between tyrosine and chlorogenic acid in plant tissues. I. Nitrous acid reactions and metal chelation of nitrosotyrosine.
Topics: Amino Acids; Caffeine; Chelating Agents; Chlorogenic Acid; Copper; Histocytochemistry; Methods; Microscopy; Nitrites; Nitroso Compounds; Phenylalanine; Plants; Spectrophotometry; Tyrosine | 1968 |
Influence of cold exposure on catecholamine depleting actions of hydroxylase inhibitors.
Topics: Adaptation, Physiological; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Cold Temperature; Epinephrine; Liver; Male; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Myocardium; Norepinephrine; Phenylalanine; Rats; Spleen; Time Factors; Tyrosine | 1968 |
Heterogeneity in genetic control of phenylalanine metabolism in man.
Topics: Child, Preschool; Heterozygote; Humans; Infant; Molecular Biology; Phenylalanine; Phenylketonurias; Tyrosine; Veins | 1968 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
Excretion of delta-aminolevulinic acid in the absence of demonstrable erythropoiesis.
Topics: Adolescent; Amino Acids; Aminobutyrates; Ammonia; Anemia, Aplastic; Autoanalysis; Chemistry, Clinical; Child; Child, Preschool; Chromatography, Ion Exchange; Erythropoiesis; Heme; Histidine; Humans; Lead Poisoning; Levulinic Acids; Lysine; Middle Aged; Ornithine; Phenylalanine; Tyrosine | 1968 |
Detection of aromatic amino acid derivatives on thin-layer chromatograms by various electron acceptors.
Topics: Amino Acids; Benzene Derivatives; Chromatography, Thin Layer; Electron Transport; Histidine; Indicators and Reagents; Methods; Peptides; Phenylalanine; Tryptophan; Tyrosine | 1968 |
An analysis of the near ultraviolet circular dichroism of insulin.
Topics: Hydrogen-Ion Concentration; Insulin; Phenylalanine; Spectrophotometry; Spectrum Analysis; Time Factors; Tyrosine; Ultraviolet Rays | 1968 |
Peroxidase isoenzymes from horseradish roots. 3. Circular dichroism of isoenzymes and apoisoenzymes.
Topics: Binding Sites; Heme; Isoenzymes; Peroxidases; Phenylalanine; Plants; Spectrophotometry; Spectrum Analysis; Tryptophan; Tyrosine; Ultraviolet Rays | 1968 |
[Thin-layer chromatographic diagnosis of phenylketonuria].
Topics: Chromatography, Thin Layer; Fluorometry; Humans; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1968 |
Conversion of phenylalanine to tyrosine by microorganisms.
Topics: Ascomycota; Aspartic Acid; Bacteria; Basidiomycota; Carbon Isotopes; Fungi; Glutamates; Marine Biology; Phenylalanine; Pseudomonas; Streptomyces; Tyrosine; Yeasts | 1968 |
Isotope studies on the mechanism of action of adrenal tyrosine hydroxylase.
Topics: Adrenal Glands; Animals; Cattle; Chromatography, Paper; Dihydroxyphenylalanine; Guinea Pigs; Mixed Function Oxygenases; Oxygen; Oxygen Isotopes; Phenylalanine; Rats; Spectrum Analysis; Tritium; Tyrosine | 1968 |
Inhibition of rat brain tryptophan hydroxylase by 6-halotryptophans.
Topics: Animals; Brain; Brain Chemistry; Carbon Isotopes; Catecholamines; Dihydroxyphenylalanine; Halogens; In Vitro Techniques; Methyltyrosines; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine | 1968 |
Formation and occurrence of N-malonylphenylalanine and related compounds in plants.
Topics: Amino Acids; Carbon Isotopes; Chromatography, Paper; Chromatography, Thin Layer; Edible Grain; Esters; Infrared Rays; Isoleucine; Leucine; Malonates; Phenylalanine; Seeds; Spectrophotometry; Stereoisomerism; Tryptophan; Tyrosine; Valine | 1968 |
Elevated plasma phenylalanine concentration and lysine incorporation into ribosomal protein of developing brain.
Topics: Animals; Brain; Carbon Isotopes; Centrifugation; Chromatography, Ion Exchange; Lysine; Nerve Tissue Proteins; Phenylalanine; Rabbits; Radiometry; Ribosomes; RNA; Tyrosine | 1968 |
A study of 2,4,6-trinitrobenzenesulfonic acid for automated amino acid chromatography.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Autoanalysis; Chromatography; Cystine; Glycine; Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Isoleucine; Leucine; Lysine; Methionine; Methods; Nitrobenzenes; Phenylalanine; Proline; Serine; Spectrophotometry; Sulfonic Acids; Temperature; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1968 |
Disorders of tyrosine metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Birth Weight; Child, Preschool; Diet Therapy; Humans; Infant; Infant, Newborn; Methionine; Phenylalanine; Tyrosine | 1968 |
Primary structure of insoluble tendon collagen. 3. Analysis of products of tryptic digestion of native collagen.
Topics: Achilles Tendon; Alanine; Aldehydes; Amino Acids; Animals; Arginine; Cattle; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Electrophoresis; Glutamine; Glycine; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Proline; Serine; Sulfur; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Binding-induced alterations in ultraviolet absorption of native serum albumin.
Topics: Animals; Binding Sites; Cattle; Cystine; Detergents; Histidine; Phenylalanine; Protein Binding; Serum Albumin, Bovine; Spectrum Analysis; Sulfates; Sulfonic Acids; Tryptophan; Tyrosine; Ultraviolet Rays; Viscosity | 1968 |
Trace metal requirements for malformin biosynthesis.
Topics: Alanine; Amino Acids; Anti-Bacterial Agents; Arginine; Aspartic Acid; Aspergillus; Chromium; Cobalt; Copper; Cysteine; Glutamine; Glycine; Histidine; Iron; Isoleucine; Leucine; Lysine; Manganese; Metals; Molybdenum; Peptide Biosynthesis; Phenylalanine; Plant Growth Regulators; Proline; Serine; Trace Elements; Tryptophan; Tyrosine; Valine; Zinc | 1968 |
Effect of adrenergic drugs on the lantern of the larval Photuris firefly.
Topics: Acetylcholine; Amphetamine; Animals; Atropine; Butyrates; Dopamine; Epinephrine; Insecta; Isoproterenol; Norepinephrine; Oxygen; Phenylalanine; Physostigmine; Reserpine; Serotonin; Sympathomimetics; Tyramine; Tyrosine | 1968 |
[An improved differentiation of amino acids with ninhydrin].
Topics: Amino Acids; Aminoisobutyric Acids; Biochemical Phenomena; Biochemistry; Chromatography; Fluorescence; Glutamates; Indicators and Reagents; Methods; Phenylalanine; Tryptophan; Tyrosine; Ultraviolet Rays | 1968 |
The action of dipeptidyl transferase as a polymerase.
Topics: Alanine; Amides; Animals; Carbon Isotopes; Cattle; Chemical Phenomena; Chemistry; Electrophoresis; Glycine; Peptides; Phenylalanine; Spleen; Transferases; Tyrosine | 1968 |
Biosynthesis of phytoquinones. Biosynthetic origins of the nuclei and satellite methyl groups of plastoquinone, tocopherols and tocopherolquinones in maize shoots, bean shoots and ivy leaves.
Topics: Amino Acids; Carbon Isotopes; Euglena; Methionine; Phenylacetates; Phenylalanine; Plants; Quinones; Tyrosine; Vitamin E; Zea mays | 1968 |
[Relations between phenylalanine and cancerous cells].
Topics: Amino Acids; Animals; Diet Therapy; Humans; Neoplasms; Phenylalanine; Proteins; Tyrosine | 1968 |
Case-finding in phenylketonuria: 3. One-way paper chromatography of amino acids in blood.
Topics: Amino Acids; Chromatography, Paper; Humans; Infant, Newborn; Infant, Newborn, Diseases; Methods; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
Function of isolated bovine thyroid polyribosomes.
Topics: Amino Acids; Animals; Antigen-Antibody Reactions; Carbon Isotopes; Cattle; Chemical Precipitation; Glutamates; In Vitro Techniques; Liver; Mercaptoethanol; Phenylalanine; Ribosomes; RNA, Transfer; Thyroglobulin; Thyroid Gland; Tritium; Tyrosine | 1968 |
[L-tryptophan metabolism in phenylketonuria].
Topics: Adolescent; Adult; Child; Diet Therapy; Female; Humans; Indoles; Kynurenine; Male; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 1968 |
Degradation of phenylalanine and tyrosine by Sporobolomyces roseus.
Topics: Benzoates; Carbon Dioxide; Carbon Isotopes; Catechols; Cell-Free System; Chromatography, Paper; Cinnamates; Coumarins; Infrared Rays; Lactones; Mitosporic Fungi; Phenylalanine; Spectrophotometry; Time Factors; Tyrosine; Ultraviolet Rays | 1968 |
Seizure threshold and excess dietary amino acids.
Topics: Age Factors; Animals; Body Weight; Diet; Ethyl Ethers; Methionine; Myoclonus; Phenylalanine; Rats; Seizures; Tyrosine | 1968 |
[Separation and study of the antigenic properties of peptides obtained by degradation of gliadin by various alkaline phosphatase preparations].
Topics: Alkaline Phosphatase; Animals; Antigens; Chromatography, Gel; Horses; Immune Sera; Immunoelectrophoresis; Isoflurophate; Phenylalanine; Plant Proteins; Rabbits; Radioimmunoassay; Triticum; Tyrosine | 1968 |
Atypical phenylketonuria in a seven-year-old profoundly retarded girl: development of phenylalanine tolerance, in spite of apparently continued failure to convert phenylalanine to tyrosine.
Topics: Adolescent; Drug Tolerance; Female; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
Conversion of phenylalanine to tyrosine in the bovine mammary secretory cell.
Topics: Animals; Carbon Isotopes; Caseins; Cattle; Female; Kidney; Lactation; Lactoglobulins; Liver; Mammary Glands, Animal; Mixed Function Oxygenases; Muscles; Myocardium; Phenylalanine; Pregnancy; Rats; Tyrosine | 1968 |
A sensitive hydroosmotic toad bladder assay. Affinity and intrinsic activity of neurohypophyseal peptides.
Topics: Alanine; Animals; Anura; Arginine; Biological Assay; Hydrogen-Ion Concentration; Isoleucine; Ornithine; Oxytocin; Peptides; Phenylalanine; Pituitary Hormones, Posterior; Theophylline; Time Factors; Tyrosine; Urinary Bladder; Valine; Vasopressins; Vasotocin; Water-Electrolyte Balance | 1968 |
[Fundamental study on the treatment of retinitis pigmentosa. 7].
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Phenylalanine; Retinitis Pigmentosa; Tryptophan; Tyrosine | 1968 |
Hereditary tyrosinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Consanguinity; Diet Therapy; Humans; Methionine; Phenylalanine; Phenylhydrazines; Pyruvate Oxidase; Tyrosine | 1968 |
Photochemical yields in ribonuclease and oxidized glutathione irradiated at different wavelengths in the ultraviolet.
Topics: Cystine; Energy Transfer; Glutathione; Histidine; Phenylalanine; Radiation Effects; Radiochemistry; Ribonucleases; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1968 |
Studies on chemotaxis. X. Inhibition of chemotaxis of rabbit neutrophil polymorphonuclear leucocytes.
Topics: Aminocaproates; Animals; Antibodies; Antigens; Ascites; Cell Movement; Chemotaxis; Glutamates; Glycine; Glycogen; In Vitro Techniques; Iodine Isotopes; Neutrophils; Phagocytosis; Phenylalanine; Rabbits; Tyrosine | 1968 |
Diagnosis and treatment of tyrosinosis.
Topics: Amino Acid Metabolism, Inborn Errors; Diet Therapy; Female; Humans; Infant; Liver Function Tests; Phenylalanine; Tyrosine; Vitamin D | 1968 |
Structural analysis of the glycine-rich, arginine-rich histone. I. Sequence of the carbosyl-terminal portion.
Topics: Amino Acid Sequence; Animals; Arginine; Aspartic Acid; Bromine; Carboxypeptidases; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Electrophoresis; Glycine; Histones; Peptides; Phenylalanine; Serine; Thymus Gland; Trypsin; Tyrosine | 1968 |
Calf and pea histone IV. I. Amino acid compositions and the identical COOH-terminal 19-residue sequence.
Topics: Alanine; Amino Acid Sequence; Amino Acids; Animals; Arginine; Aspartic Acid; Biological Evolution; Bromine; Cattle; Chromatography, Gel; Chymotrypsin; Cyanides; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Plants; Proline; Serine; Threonine; Trypsin; Tyrosine; Valine | 1968 |
Daily rhythm in plasma tyrosine and phenylalanine.
Topics: Animals; Circadian Rhythm; Corticosterone; Diet; Humans; Hydrocortisone; Male; Methods; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1968 |
Simultaneous determination of alpha S1-, beta-, and kappa-caseins in whole casein by using carboxypeptidase A.
Topics: Amino Acid Sequence; Amino Acids; Autoanalysis; Carboxypeptidases; Caseins; Chromatography, Ion Exchange; Methods; Phenylalanine; Protein Hydrolysates; Tyrosine | 1968 |
Tryptophan transaminase from Clostridium sporogenes.
Topics: Buffers; Cell-Free System; Centrifugation, Density Gradient; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography, Ion Exchange; Clostridium; Electrophoresis; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; Models, Biological; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Transaminases; Tryptophan; Tyrosine | 1968 |
Reactions of aromatic and sulfur amino acids in ribonuclease with hydrogen atoms in water solution.
Topics: Alanine; Amino Acids; Aminobutyrates; Chemical Phenomena; Chemistry; Chromatography, Gel; Cystine; Hydrogen; Kinetics; Methionine; Phenylalanine; Ribonucleases; Solutions; Sulfur; Tyrosine | 1968 |
Two procedures for accelerated separation of amino acids by column chromatography.
Topics: Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Buffers; Chromatography, Ion Exchange; Cystine; Glutamates; Glycine; Isoleucine; Leucine; Methionine; Methods; Phenylalanine; Proline; Serine; Temperature; Threonine; Tryptophan; Tyrosine; Valine | 1968 |
Gas chromatographic behavior of trimethylsilylated phenylthiohydantoin amino acids.
Topics: Alanine; Amino Acids; Arginine; Chromatography, Gas; Glutamates; Glutamine; Hydantoins; Leucine; Methionine; Methods; Methylation; Phenylalanine; Proline; Serine; Silicon; Spectrum Analysis; Tyrosine | 1968 |
[A suitable arginine derivative for mass spectrometry and gas chromatography].
Topics: Arginine; Chromatography, Gas; Esters; Hydroxyproline; Methionine; Ornithine; Phenylalanine; Pyrimidines; Spectrum Analysis; Tyrosine | 1968 |
Methionine and glycine levels in the liver of riboflavin deficient rats.
Topics: Alanine; Animals; Autoanalysis; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Methionine; Phenylalanine; Rats; Riboflavin Deficiency; Tyrosine; Valine | 1968 |
[Deficit of essential amino acids in endogenous depression].
Topics: Adolescent; Adult; Aged; Antidepressive Agents; Depression; Female; Humans; Injections, Intravenous; Male; Middle Aged; Phenylalanine; Tryptophan; Tyrosine | 1968 |
Influence of protein digestion on plasma amino acid levels in sheep.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Caseins; Digestion; Glutamates; Glycine; Histidine; Intestinal Mucosa; Isoleucine; Leucine; Lysine; Male; Phenylalanine; Proline; Sheep; Tyrosine; Valine | 1968 |
Brain aromatic aminotransferase. I. Purification and some properties of pig brain L-phenylalanine-2-oxoglutarate aminotransferase.
Topics: Animals; Arsenic; Aspartic Acid; Borates; Brain; Buffers; Chemical Precipitation; Chloromercuribenzoates; Chromatography; Hydrogen-Ion Concentration; Ion Exchange; Keto Acids; Ketoglutaric Acids; Kinetics; Mercaptoethanol; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Succinates; Swine; Transaminases; Tyrosine; Vibration | 1968 |
[Tyrosinosis].
Topics: Diet Therapy; Humans; Hypertension, Portal; Liver Cirrhosis; Metabolism, Inborn Errors; Phenylalanine; Renal Tubular Transport, Inborn Errors; Rickets; Tyrosine; Vitamin D | 1968 |
Autodigestion of the main proteolytically active component of the stem bromelain.
Topics: Alanine; Arginine; Bromelains; Chromatography; Glutamates; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1968 |
[Tyrosinosis].
Topics: Diet Therapy; Humans; Hypertension, Portal; Liver Cirrhosis; Metabolism, Inborn Errors; Phenylalanine; Renal Tubular Transport, Inborn Errors; Rickets; Tyrosine; Vitamin D | 1968 |
Studies on DOPA- and dopamine-hyperglycemia.
Topics: Amines; Amino Acids; Animals; Blood Glucose; Dihydroxyphenylalanine; Dopamine; Epinephrine; Hyperglycemia; Phenylalanine; Rabbits; Tyrosine | 1968 |
The exogenous environment as a factor in the control of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of Neurospora crassa.
Topics: Aldehyde-Lyases; Alleles; Enzyme Repression; Heptoses; Methods; Neurospora; Phenylalanine; Phosphates; Tyrosine | 1968 |
[Free blood amino acids in rheumatic hildren].
Topics: Adolescent; Amino Acids; Child; Chromatography, Paper; Humans; Phenylalanine; Rheumatic Fever; Tyrosine | 1968 |
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine | 1968 |
Dietary treatment of infantile tyrosinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Diet Therapy; Humans; Infant; Liver; Liver Function Tests; Male; Milk; Phenylalanine; Tyrosine | 1968 |
[Heterozygote identification in phenylketonuria].
Topics: Heterozygote; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1968 |
Effect of different patterns of excess amino acids on performance of chicks fed amino acid-deficient diets.
Topics: Amino Acids; Animals; Arginine; Body Weight; Chickens; Cystine; Deficiency Diseases; Diet Therapy; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Threonine; Tryptophan; Tyrosine | 1969 |
Exertion of delta-aminolevulinic acid in hereditary tyrosinemia.
Topics: Abdomen; Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Creatinine; Feces; Female; Humans; Leg; Levulinic Acids; Male; Pain; Paresis; Phenylalanine; Porphyrins; Pyrroles; Tritium; Tyrosine | 1969 |
Photochemical addition of amino acids to 14C-uracil.
Topics: Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; DNA; Phenylalanine; Proteins; Radiation Effects; Tyrosine; Ultraviolet Rays; Uracil | 1969 |
Umbilical vein-artery and uterine arterio-venous plasma amino acid differences (in the human subject).
Topics: Amino Acids; Analysis of Variance; Cesarean Section; Delivery, Obstetric; Female; Fetus; Gestational Age; Histidine; Humans; Infant, Newborn; Infant, Premature; Leucine; Lysine; Maternal-Fetal Exchange; Nitrogen; Phenylalanine; Placenta; Pregnancy; Serine; Tyrosine; Umbilical Arteries; Umbilical Veins; Uterus | 1969 |
Oral phenylalanine and tyrosine tolerance tests in Parkinsonian patients.
Topics: Adult; Aged; Female; Humans; Intestinal Absorption; Male; Middle Aged; Parkinson Disease; Phenylalanine; Statistics as Topic; Tyrosine; Xylose | 1969 |
[On the evolution of endopeptidases. VII. A protease of molecular weight 12500 with chymotryptic properties from larvae of Vespa orientalis].
Topics: Animals; Chromatography, Gel; Chymotrypsin; Electrophoresis; Esters; Insecta; Intestines; Methyl Chloride; Molecular Weight; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Sulfonic Acids; Tyrosine | 1969 |
Phenylalanine tolerance tests. In families with phenylketonuria and hyperphenylalaninemia.
Topics: Age Factors; Child, Preschool; Diagnosis, Differential; Humans; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Methods; Phenylalanine; Phenylketonurias; Tyrosine | 1969 |
Comparison of halogenated phenylalanine analogues as inhibitors as particle-bound and soluble tyrosine hydroxylase.
Topics: Adrenal Medulla; Amino Acids; Animals; Bromine; Cattle; Chlorine; Fluorine; Halogens; Iodine; Kinetics; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Tritium; Tyrosine | 1969 |
Effect of glucagon on concentration of several free amino acids in plasma.
Topics: Alanine; Amino Acids; Arginine; Citrulline; Cystine; Depression, Chemical; Fasting; Female; Glucagon; Glycine; Histidine; Humans; Leucine; Liver; Lysine; Male; Methionine; Nitrogen; Phenylalanine; Progesterone; Proline; Serine; Threonine; Tyrosine; Valine | 1969 |
Recovery after dietary treatment of an infant with features of tyrosinosis.
Topics: Amino Acid Metabolism, Inborn Errors; Cholestasis; Diet Therapy; Female; Growth Disorders; Humans; Hypophosphatemia, Familial; Infant; Methionine; Phenylalanine; Phosphates; Renal Aminoacidurias; Rickets; Tyrosine | 1969 |
Fractionation of rat liver transfer ribonucleic acid. Isolation of tyrosine, valine, serine, and phenylalanine transfer ribonucleic acids and their coding properties.
Topics: Amino Acids; Animals; Carbon Isotopes; Chromatography, Gel; Chromatography, Ion Exchange; Genetic Code; Ligases; Liver; Male; Phenylalanine; Rats; Ribosomes; RNA, Transfer; Serine; Templates, Genetic; Tyrosine; Valine | 1969 |
Separation and identification of 14C-labeled glucogenic compounds by paper chromatography.
Topics: Alanine; Autoradiography; Carbon Isotopes; Chromatography, Paper; Fructose; Fumarates; Gluconeogenesis; Glucose; Glutamates; Glycerophosphates; Hexosephosphates; Ketoglutaric Acids; Lactates; Malates; Methods; Phenylalanine; Phosphates; Pyruvates; Succinates; Tyrosine | 1969 |
Results of mass screening for hyperaminoacidemias in the newborn infant.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Blood Chemical Analysis; Chromatography; Female; Humans; Infant; Infant, Newborn; Male; Mass Screening; Methionine; Methods; Phenylalanine; Tyrosine | 1969 |
Causes for high phenylalanine with normal tyrosine in newborn screening programs.
Topics: Amino Acids; Child; Child, Preschool; Chromosomes; Diet Therapy; Genes, Recessive; Humans; Infant; Infant, Newborn; Intellectual Disability; Intelligence Tests; Mass Screening; Methods; Phenylalanine; Phenylketonurias; Tyrosine; United States | 1969 |
Hair amino acids in cystinosis, homocystinuria, Fölling's disease and tyrosinosis.
Topics: Amino Acids; Autoanalysis; Citrulline; Cystine; Cystinosis; Female; Hair; Homocysteine; Homocystinuria; Humans; In Vitro Techniques; Male; Metabolic Diseases; Methionine; Methods; Phenylalanine; Phenylketonurias; Proline; Tyrosine | 1969 |
Filter paper blood collection and punching as a means of quantification.
Topics: Blood Glucose; Blood Specimen Collection; Blood Urea Nitrogen; Filtration; Hematocrit; Humans; Methods; Paper; Phenylalanine; Tyrosine | 1969 |
Connection between chemical structure and antithiamine activity of various phenol derivatives.
Topics: Aldehydes; Benzene; Benzoates; Biological Assay; Catechols; Chlorides; Chlorogenic Acid; Cinnamates; Copper; Dopamine; Esters; Hydroquinones; Iron; Methods; Phenols; Phenylacetates; Phenylalanine; Phloroglucinol; Potassium; Pyrogallol; Resorcinols; Thiamine; Tyrosine | 1969 |
Flavinyl peptides. II. Intramolecular interactions in flavinyl aromatic amino acid peptides.
Topics: Chemical Phenomena; Chemistry; Dimethylformamide; Flavins; Fluorescence; Fluorometry; Peptides; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1969 |
[Alkaloids in the metabolism of plants].
Topics: Alkaloids; Dopamine; Indoles; Isoquinolines; Mevalonic Acid; ortho-Aminobenzoates; Papaver; Penicillium; Phenylalanine; Pipecolic Acids; Plants, Medicinal; Pregnenolone; Quinazolines; Sparteine; Terpenes; Tryptophan; Tyrosine | 1969 |
The assessment of nutritional status in protein-malnourished children.
Topics: Amino Acids; Blood Proteins; Child; Child Nutritional Physiological Phenomena; Histidine; Humans; Hydroxyproline; Kwashiorkor; Phenylalanine; Protein Deficiency; Tyrosine; Uganda | 1969 |
Mode of action of p-chlorophenylalanine on Pseudomonas species (11299a).
Topics: Amino Acids; Asparagine; Bacterial Proteins; Biological Transport; Carbon Isotopes; Cell-Free System; Culture Media; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Tyrosine | 1969 |
Pyrrolidonecarboxylyl peptidase: studies on the specificity of the enzyme.
Topics: Alanine; Chemical Phenomena; Chemistry; Dipeptides; Isoleucine; Leucine; Peptide Hydrolases; Phenylalanine; Proline; Pseudomonas; Pyrrolidinones; Stereoisomerism; Tyrosine; Valine | 1969 |
[On the biosynthesis of capsaicin].
Topics: Acetates; Alkaloids; Capsicum; Carbon Isotopes; Mevalonic Acid; Phenylalanine; Plants, Medicinal; Tyrosine | 1969 |
Hereditary tyrosinemia. 3. On the differential diagnosis and the lack of effect of early dietary treatment.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Chromatography, Gas; Diagnosis, Differential; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Liver Cirrhosis; Male; Phenylalanine; Time Factors; Tyrosine | 1969 |
Phenylalanine hydroxylase activity in mammalian cells.
Topics: Animals; Boranes; Brain; Carbon Isotopes; Chromatography, Paper; Fluorometry; Kidney; Kinetics; Liver; Mice; Mixed Function Oxygenases; Muscles; Pancreas; Phenylalanine; Tissue Extracts; Tyrosine | 1969 |
Urinary amino acid and peptide excretion patterns in patients with muscular dystrophy (Duchenne). A preliminary study with the autoanalyzer.
Topics: Adolescent; Alanine; Amino Acid Metabolism, Inborn Errors; Aspartic Acid; Autoanalysis; Child; Child, Preschool; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Lysine; Male; Muscular Dystrophies; Peptides; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1969 |
The net absorption of the amino acid constituents of a protein meal in normal and cystinuric subjects.
Topics: Adult; Amino Acids; Arginine; Cystine; Cystinuria; Dietary Proteins; Female; Glycols; Humans; Indicators and Reagents; Intestinal Absorption; Lysine; Male; Phenylalanine; Tyrosine | 1969 |
The effect of phenylalanine and its metabolites on glucose utilization in developing brain.
Topics: Animals; Brain; Carbon Isotopes; Glucose; Oxygen Consumption; Phenylalanine; Phenylpyruvic Acids; Rabbits; Tyrosine | 1969 |
Synthetic inhibitors and ester substrates of pancreatic kallikrein.
Topics: Amidines; Amino Acids; Animals; Arginine; Chemical Phenomena; Chemistry; Esters; Indoleacetic Acids; Kallikreins; Keto Acids; Leucine; Methionine; Pancreas; Phenylalanine; Phenylpyruvic Acids; Pyruvates; Swine; Trypsin Inhibitors; Tryptamines; Tryptophan; Tyrosine | 1969 |
Separation of phenylalanine, tyrosine and trypotphan by chromatography on poly-N-vinyl pyrrolidone.
Topics: Chromatography; Phenylalanine; Povidone; Tryptophan; Tyrosine | 1969 |
Aminoacyl-RNA synthetase and transfer RNA binding activity during early mammalian brain development.
Topics: Adenosine Triphosphate; Age Factors; Amino Acids; Animals; Arginine; Brain; Carbon Isotopes; Chromatography, Gel; Colorimetry; Drug Synergism; In Vitro Techniques; Ligases; Mice; Phenylalanine; RNA, Transfer; Tritium; Tyrosine | 1969 |
Investigations of the chymotrypsin-catalyzed hydrolysis of specific substrates. IV. Pre-steady state kinetic approaches to the investigation of the catalytic hydrolysis of esters.
Topics: Acridines; Amides; Amino Acids; Chymotrypsin; Computers, Analog; Esters; Hydrogen-Ion Concentration; Kinetics; Methods; Nitrophenols; Oscillometry; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1969 |
Studies on the metabolism of the phenolic acids in hereditary tyrosinemia by a gas-liquid chromatographic method.
Topics: Acids; Adolescent; Amino Acid Metabolism, Inborn Errors; Child; Chromatography, Gas; Female; Humans; Infant; Male; Methods; Phenols; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Tyrosine | 1969 |
Location of hydrogen transfer steps in the mechanism of reduction of L-amino acid oxidase.
Topics: Amino Acid Oxidoreductases; Chemical Phenomena; Chemistry; Deuterium; Flavin-Adenine Dinucleotide; Glycine; Hydrogen; Kinetics; Phenylalanine; Spectrophotometry; Tritium; Tyrosine | 1969 |
[On phenylketonuria with normal intelligence].
Topics: Aged; Carcinoma, Squamous Cell; Diet Therapy; Humans; Intelligence; Male; Mental Disorders; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Skin Neoplasms; Tyrosine | 1969 |
Direct synthesis of p-methoxybenzyl carbazate and p-methoxybenzyloxycarbonylamino acids using p-methoxybenzyl chloroformate as reagent.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Chloroform; Glutamates; Glutamine; Glycine; Hydrazines; Indicators and Reagents; Isoleucine; Leucine; Phenylalanine; Proline; Sodium Hydroxide; Stereoisomerism; Threonine; Tyrosine; Valine | 1969 |
Local solvent structure as a factor in secondary isotope fractionation phenomena of labeled amino acids on ion-exchange columns.
Topics: Alcohols; Amino Acids; Carbon Isotopes; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Glutamates; Glycine; Phenylalanine; Proline; Serine; Solvents; Tritium; Tyrosine | 1969 |
Detection of heterozygotes for phenylketonuria by column chromatography and discriminatory analysis.
Topics: Adolescent; Adult; Aged; Chromatography; Female; Heterozygote; Humans; Male; Middle Aged; Paternity; Phenylalanine; Phenylketonurias; Statistics as Topic; Tyrosine | 1969 |
[Studies on the amino acid composition of some African legumes].
Topics: Amino Acids; Arginine; Aspartic Acid; Canavanine; Chromatography; Cystine; Food Analysis; Glutamine; Glycine; Histidine; Hot Temperature; Isoleucine; Leucine; Lysine; Methionine; Methods; Phenylalanine; Plants, Edible; Proline; Proteins; Serine; Threonine; Tryptophan; Tyrosine; Valine; Vegetables | 1969 |
Studies concerning the biochemical genetics and physiology of activity and allosteric inhibition mutants of Neurospora crassa 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Topics: Aldehyde-Lyases; Binding Sites; Carbohydrates; Chromatography, Gel; Chromosome Mapping; Depression, Chemical; Feedback; Genes; Genetic Code; Genetics, Microbial; Isoenzymes; Mutation; Neurospora; Peptides; Phenylalanine; Polysaccharides; Tryptophan; Tyrosine | 1969 |
Plasma amino acid levels and insulin secretion in obesity.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine | 1969 |
Prephenate dehydrogenase from Neurospora: feedback activation by phenylalanine.
Topics: Amino Acids; Benzoates; Chemical Phenomena; Chemistry; Cyclohexanes; Feedback; Fluorometry; Genes; Hydro-Lyases; Isomerases; Mutation; Neurospora; Phenylalanine; Phenylpyruvic Acids; Phosphotransferases; Pyruvates; Tyrosine | 1969 |
The formation of oxalic acid from the side chain of aromatic amino acids in the rat.
Topics: Alanine; Amino Acid Oxidoreductases; Animals; Carbon Dioxide; Carbon Isotopes; Chemical Phenomena; Chemistry; Hippurates; Male; Oxalates; Phenylalanine; Rats; Snakes; Tryptophan; Tyrosine; Venoms | 1969 |
Histones in early embryogenesis.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Echinodermata; Electrophoresis; Embryo, Nonmammalian; Fishes; Gels; Genetic Code; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1969 |
Hyperphenylalaninemia: effect on the developing rat brain.
Topics: Aging; Animals; Animals, Newborn; Body Weight; Brain; Humans; Injections, Subcutaneous; Lipid Metabolism; Liver; Mixed Function Oxygenases; Myelin Sheath; Organ Size; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1969 |
Effects of experimentally induced phenylketonuria on seizure susceptibility in mice.
Topics: Animals; Brain Chemistry; Diet; Humans; Mice; Norepinephrine; Phenylalanine; Phenylketonurias; Seizures; Serotonin; Tyrosine | 1969 |
[Fundamental study on the treatment of retinitis pigmentosa. (8)].
Topics: Amino Acids; Animals; Blood; Diet; Electroretinography; Injections; Male; Organ Size; Phenylalanine; Rats; Retinitis Pigmentosa; Time Factors; Tyrosine | 1969 |
[Structure of peptides isolated from chymotrypsin hydrolysates of horse myoglobin].
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine; Carboxypeptidases; Chromatography, Gel; Chymotrypsin; Dinitrophenols; Histidine; Horses; Leucyl Aminopeptidase; Methionine; Myoglobin; Peptides; Phenylalanine; Tryptophan; Tyrosine | 1969 |
The effects of individual amino acids on the incorporation of labelled amino acids into proteins by brain homogenates.
Topics: Amino Acids; Animals; Brain; Carbon Isotopes; Centrifugation; Female; Histidine; Isoleucine; Leucine; Liver; Lysine; Male; Nerve Tissue Proteins; Phenylalanine; Rats; Spectrum Analysis; Threonine; Tyrosine; Valine | 1969 |
Persistent mild hyperphenylalaninemia in various ethnic groups in Israel.
Topics: Child, Preschool; Female; Humans; Infant; Infant, Newborn; Israel; Male; Mass Screening; Phenylalanine; Phenylketonurias; Tyrosine; White People | 1969 |
Radiolysis of phenylalanine and tyrosine and aqueous solution.
Topics: Carbon Isotopes; Dihydroxyphenylalanine; Oxygen; Phenylalanine; Radiation Effects; Radiochemistry; Solutions; Spectrum Analysis; Tyrosine | 1969 |
Hemoglobin Philly (beta 35 tyrosine phenylalanine): studies in the molecular pathology of hemoglobin.
Topics: Amino Acids; Anemia, Hemolytic, Congenital; Child; Chromatography; Culture Techniques; Electrophoresis; Erythrocytes; Female; Hemoglobinopathies; Hemoglobins, Abnormal; Humans; Male; Mutation; Phenylalanine; Spectrophotometry; Sulfhydryl Compounds; Tyrosine; Ultracentrifugation | 1969 |
On the biosynthesis of cyclopenin and cyclopenol, benzodiazepine alkaloids from Penicillium cyclopium Westling.
Topics: Alkaloids; Azepines; Carbon Isotopes; Chromatography, Thin Layer; Methionine; Nitrogen; ortho-Aminobenzoates; Penicillium; Phenylalanine; Radioisotopes; Tritium; Tyrosine | 1969 |
Phenylalanine and tyrosine synthesis under primitive earth conditions.
Topics: Biological Evolution; Electricity; Hydrocarbons; Methods; Models, Chemical; Phenylalanine; Temperature; Tyrosine; Ultraviolet Rays | 1969 |
Affinity chromatography of a regulatory enzyme based on specific interaction with the effector.
Topics: Aldehyde-Lyases; Binding Sites; Chromatography, Ion Exchange; Heptoses; Isoenzymes; Methods; Phenylalanine; Saccharomyces; Tyrosine | 1969 |
The effects of alterations in hypothalamic monoamine content on fever in the rabbit.
Topics: Amines; Animals; Body Temperature Regulation; Catecholamines; Fever; Hypothalamus; Injections, Intraperitoneal; Leukocytes; Phenylalanine; Pyrogens; Rabbits; Serotonin; Tyrosine | 1969 |
The formation and metabolism of phenyl-substituted fatty acids in the ruminant.
Topics: Animals; Benzoates; Carbon Isotopes; Chromatography, Gas; Fatty Acids; In Vitro Techniques; Intestinal Mucosa; Kidney; Liver; Phenylacetates; Phenylalanine; Propionates; Rumen; Sheep; Tryptophan; Tyrosine; Urine | 1964 |
On the mechanism of oxidative cleavage of aryl-alkyl ethers by liver microsomes.
Topics: Acetanilides; Animals; Chromatography, Paper; In Vitro Techniques; Liver; Microsomes; Mixed Function Oxygenases; Phenylalanine; Rabbits; Tyrosine | 1965 |
Studies on metabolism of vitamin A. 7. Lowered biosynthesis of ascorbic acid in vitamin A-deficient rats.
Topics: Animals; Ascorbic Acid; Blood; Chlorobutanol; Kidney; Liver; Microsomes; Oxidoreductases; Phenylalanine; Rats; Threonine; Tyrosine; Urine; Vitamin A Deficiency | 1964 |
Transamination in plants. The specificity of an aminotransferase from mung bean.
Topics: Amino Acids; Arginine; Dihydroxyphenylalanine; Glutamine; In Vitro Techniques; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Plants, Edible; Transaminases; Tryptophan; Tyrosine | 1965 |
Phenylalanine ammonia-lyase in sliced sweet potato roots.
Topics: Chromatography; Cinnamates; In Vitro Techniques; Lyases; Phenols; Phenylalanine; Spectrophotometry; Tyrosine; Vegetables | 1965 |
Uptake of L-tyrosine and 3-0-methylglucose by isolated intestinal epithelial cells.
Topics: Animals; Biological Transport; Carbon Dioxide; Dinitrophenols; Epithelium; Hexoses; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Oxygen Consumption; Phenylalanine; Rabbits; Tyrosine | 1965 |
Inhibitors of purified beef adrenal tyrosine hydroxylase.
Topics: Adrenal Glands; Amino Acids; Animals; Catechols; Cattle; Diiodotyrosine; Enzymes; In Vitro Techniques; Kinetics; Methyltyrosines; Mixed Function Oxygenases; Phenylalanine; Tryptophan; Tyrosine | 1965 |
Phenylalanine ammonia-lyase in sweet potato roots: inhibition by phenylpropanoids.
Topics: Ammonia; Chemical Phenomena; Chemistry; Chlorogenic Acid; Chromatography, Paper; Cinnamates; Enzymes; In Vitro Techniques; Lyases; Phenylalanine; Plants; Spectrophotometry; Tyrosine | 1965 |
Effect of temperature on x-ray--induced light emission from powders of amino acids and trypsin.
Topics: Fluorescence; Luminescent Measurements; Phenylalanine; Powders; Radiation Effects; Radiochemistry; Temperature; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays | 1965 |
Biosynthesis of phenolic acids by certain wood-destroying basidiomycetes.
Topics: Acetates; Basidiomycota; Cinnamates; Glucose; In Vitro Techniques; Infrared Rays; Lyases; Phenylalanine; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1965 |
Incorporation of amino acid carbon into proteins by sheep thyroid gland mitochondria.
Topics: Amino Acids; Animals; Carbon Isotopes; Glutamates; In Vitro Techniques; Leucine; Mitochondria; Nitrobenzenes; Phenylalanine; Protein Biosynthesis; RNA; Serine; Sheep; Thyroid Gland; Tyrosine; Valine | 1964 |
[Biochemical and analytical bases of the exploration of phenylalanine metabolism].
Topics: Humans; Intellectual Disability; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 1964 |
Amber suppressors: efficiency of chain propagation and suppressor specific amino acids.
Topics: Amino Acids; Autoradiography; Coliphages; Genes; Glutamine; In Vitro Techniques; Molecular Biology; Mutation; Peptide Biosynthesis; Phenylalanine; Serine; Tyrosine | 1965 |
[Determination of phenylalanine and tyrosine by column chromatography].
Topics: Chemical Phenomena; Chemistry; Chromatography; Phenylalanine; Tyrosine | 1965 |
Biosynthesis of alkaloids. On the oxidative deamination of biogenetically important amino acids in Papaver somniferum plants.
Topics: Alkaloids; Amino Acids; Oxidation-Reduction; Papaver; Phenylalanine; Plants, Medicinal; Tyrosine | 1965 |
Labelling of beta-lipoprotein with tritium.
Topics: Acetates; Cholesterol; Immunoelectrophoresis; In Vitro Techniques; Indicators and Reagents; Lipoproteins; Methionine; Phenylalanine; Serine; Tritium; Tryptophan; Tyrosine | 1965 |
Ultra-violet absorption spectra of haemoglobins from various vertebrates.
Topics: Animals; Artiodactyla; Birds; Dogs; Guinea Pigs; Hemoglobins; In Vitro Techniques; Phenylalanine; Rabbits; Rats; Sheep; Spectrophotometry; Swine; Tryptophan; Tyrosine; Ultraviolet Rays | 1965 |
Characteristics of the hepatic phenylalanine-hydroxylating system in newborn rats.
Topics: Animals; Animals, Newborn; Coenzymes; Humans; In Vitro Techniques; Liver; Mixed Function Oxygenases; Oxidoreductases; Phenylalanine; Phenylketonurias; Rats; Subcellular Fractions; Tyrosine | 1965 |
Effect of puromycin and insulin on amino acid accumulation by isolated intact rat diaphragm.
Topics: Alanine; Amino Acids; Animals; Biological Transport; Diaphragm; Histidine; In Vitro Techniques; Insulin; Leucine; Muscles; Phenylalanine; Protein Biosynthesis; Puromycin; Rats; Tyrosine | 1964 |
Isolation and characteristics of a fungal endopeptidase.
Topics: Amidohydrolases; Aminopeptidases; Arginine; Carboxypeptidases; Chemistry Techniques, Analytical; Enzymes; Esterases; Fluorides; In Vitro Techniques; Isoflurophate; Mitosporic Fungi; Peptide Hydrolases; Phenylalanine; Tyrosine; Ultracentrifugation | 1965 |
[Metabolic disorders of phenylalanine and tyrosine].
Topics: Animals; Humans; Metabolic Diseases; Metabolism, Inborn Errors; Phenylalanine; Tyrosine | 1965 |
Regulation of amino acid accumulation in isolated rat diagphragm: effect of puromycin and insulin.
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Cystine; Diaphragm; Histidine; In Vitro Techniques; Insulin; Isoleucine; Leucine; Male; Muscles; Phenylalanine; Proteins; Puromycin; Rats; Serine; Tryptophan; Tyrosine | 1965 |
[Study of the metabolism of an enzymatic system in phenylketonuria].
Topics: Adolescent; Child; Child, Preschool; Enzymes; Humans; Infant; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Tyrosine | 1966 |
Coenzymes and hydroxylases: ascorbate and dopamine-beta-hydroxylase; tetrahydropteridines and phenylalanine and tyrosine hydroxylases.
Topics: Ascorbic Acid; Coenzymes; Dopamine; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Pteridines; Tyrosine | 1966 |
[Non-enzymatic hydroxylation of phenylalanine to tyrosine using tetrahydrogenated pterines].
Topics: Chemical Phenomena; Chemistry; Phenylalanine; Pterins; Tyrosine | 1966 |
Amino acids in seven species of cestodes.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Cestoda; Cystine; Glutamates; Glycine; Histidine; In Vitro Techniques; Isoleucine; Leucine; Lysine; Nitrogen; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Diagnostic and therapeutic implications of persistent hyperphenylalaninemia in an infant heterozygous for the gene of phenylketonuria.
Topics: Blood; Child, Preschool; Diet Therapy; Follow-Up Studies; Humans; Liver; Phenylalanine; Phenylketonurias; Tyrosine | 1966 |
Ultraviolet light irradiated collagen macromolecules.
Topics: Chemical Phenomena; Chemistry, Physical; Collagen; Microscopy, Electron; Phenylalanine; Radiation Effects; Spectrophotometry; Tyrosine; Ultraviolet Rays | 1966 |
The spatial location of chromophoric residues in L-glutamate dehydrogenase.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Glucose; Glutamate Dehydrogenase; Glycerol; Glycols; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1966 |
In vivo formation of tyrosine from p-fluorophenylalanine.
Topics: Animals; Blood Proteins; In Vitro Techniques; Pancreas; Phenylalanine; Protein Biosynthesis; Protein Hydrolysates; Rats; Tyrosine | 1966 |
The biosynthesis of catecholamines in two genera of protozoa.
Topics: Catecholamines; Chromatography, Paper; Dihydroxyphenylalanine; Epinephrine; Eukaryota; Fluorometry; Norepinephrine; Phenylalanine; Tetrahymena; Tyrosine | 1966 |
Effects of low phenylalanine-tyrosine diets on S91 mouse melanomas.
Topics: Animals; Diet; Melanins; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Sarcoma, Experimental; Tyrosine | 1966 |
Biosynthesis of intrinsically labeled antibodies in vitro.
Topics: Animals; Antibody Formation; Culture Techniques; Immunoassay; Iodine Isotopes; Kinetics; Lymph Nodes; Phenylalanine; Rabbits; Ribonucleases; Tyrosine | 1966 |
Studies on urinary phenolic compounds in man. IV. O-Tyrosine and its metabolites.
Topics: Alkaptonuria; Humans; In Vitro Techniques; Lactates; Male; Phenylacetates; Phenylalanine; Tyramine; Tyrosine | 1966 |
Analysis of the vegetalizing action of tyrosine on the sea urchin embryo.
Topics: Amino Acids; Animals; Carbon Isotopes; Dinitrophenols; Echinodermata; Eukaryota; Glycine; Leucine; Lithium; Oxygen Consumption; Phenylalanine; Protein Biosynthesis; Tyrosine | 1966 |
Aromatic metabolism in plants. II. Enzymes of the shikimate pathway in suspension cultures of plant cells.
Topics: Alcohol Oxidoreductases; Culture Media; Hydro-Lyases; Isocitrate Dehydrogenase; Lyases; Malate Dehydrogenase; Phenylalanine; Plants; Transaminases; Tyrosine | 1966 |
Studies on coenzyme Q. The biosynthesis of coenzyme Q9 in rat tissue slices.
Topics: Acetates; Animals; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; In Vitro Techniques; Infrared Rays; Intestinal Mucosa; Kidney; Liver; Mevalonic Acid; Myocardium; Phenylalanine; Rats; Spectrophotometry; Tyrosine; Ubiquinone | 1966 |
Tolerance of phenylalanine after ntravenous administration in phenylketonurics, heterozygous carriers, and normal adults.
Topics: Adult; Drug Tolerance; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1966 |
Purification and properties of a mast cell protease.
Topics: Animals; Centrifugation; Chymotrypsin; Enzymes; Fibrinogen; Hemoglobins; In Vitro Techniques; Isoflurophate; Mast Cells; Peptide Hydrolases; Phenylalanine; Rats; Thyroglobulin; Thyroid Gland; Tyrosine | 1966 |
The optical rotatory dispersion of aromatic amino acids and the side chain-dependent Cotton effects in proteins.
Topics: Chemical Phenomena; Chemistry, Physical; Phenylalanine; Proteins; Tryptophan; Tyrosine | 1966 |
Electron localization of amines in central nervous tissue.
Topics: Animals; Cricetinae; Dihydroxyphenylalanine; Dopamine; Hypothalamus; Microscopy, Electron; Norepinephrine; Phenylalanine; Serotonin; Tyrosine | 1966 |
Effects of reducing the phenylalanine-tyrosine intake of patients with advanced malignant melanoma.
Topics: Adult; Blood; Diet Therapy; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Phenylalanine; Skin Neoplasms; Tyrosine | 1966 |
L-tryptophan metabolism in phenylketonuria.
Topics: Adolescent; Adult; Blood Chemical Analysis; Child; Child, Preschool; Chromatography; Diet; Feces; Female; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine; Urine | 1966 |
Prenatal and postnatal developmental consequences of maternal phenylketonuria.
Topics: Adult; Birth Weight; Congenital Abnormalities; Female; Fetal Diseases; Humans; Infant, Newborn; Intellectual Disability; Male; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1966 |
Phenylalanine toxicity in rats.
Topics: Alanine; Animals; Blood; Glycine; Isoleucine; Leucine; Phenylalanine; Rats; Tyrosine; Urine | 1966 |
Postnatal changes in free amino acid pool of rat brain.
Topics: Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Brain; Chromatography; Glutamates; Glutamine; Isoleucine; Leucine; Phenylalanine; Proline; Rats; Tyrosine; Valine | 1966 |
m-Carboxy-substituted aromatic amino acids in plant metabolism. II. The incorporation of shikimic acid into L-3-(3-carboxy-4-hydroxyphenyl)alanine in Reseda lutea L.
Topics: Amino Acids; Glucose; In Vitro Techniques; Phenylalanine; Plants; Shikimic Acid; Tyrosine | 1966 |
Fractionation of amino acid-specific s-RNA from silkgland by methylated albumin column chromatography.
Topics: Alanine; Albumins; Animals; Bombyx; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Glycine; In Vitro Techniques; Leucine; Lysine; Methionine; Phenylalanine; RNA, Transfer; Serine; Tyrosine | 1966 |
Phenylalanine conversion to tyrosine by the human fetal liver.
Topics: Chromatography, Ion Exchange; Fetus; Humans; In Vitro Techniques; Liver; Phenylalanine; Tyrosine | 1966 |
Aminoacidemia of prematurity. Its response to ascorbic acid.
Topics: Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Birth Weight; Blood; Female; Humans; Hydroxyindoleacetic Acid; Infant, Newborn; Infant, Premature, Diseases; Male; Phenylalanine; Tyrosine; Urine | 1966 |
Phenylalanine deficiency syndrome.
Topics: Deficiency Diseases; Diet Therapy; Female; Hematocrit; Hemoglobins; Humans; Infant; Phenylalanine; Phenylketonurias; Tyrosine | 1966 |
Some characteristics of amino acid transport in frog ovarian oocytes.
Topics: Animals; Anura; Biological Transport; Carbon Isotopes; Cell Membrane Permeability; Female; In Vitro Techniques; Kinetics; Leucine; Ovum; Phenylalanine; Tryptophan; Tyrosine | 1966 |
[Research on the tyrosine metabolism of premature infants. I. Changes in blood tyrosine and phenylalanine levels in premature infants during the 1st weeks of life].
Topics: Blood; Female; Humans; In Vitro Techniques; Infant, Newborn; Infant, Premature; Male; Phenylalanine; Tyrosine | 1966 |
Detection of phenylketonuria in newborn infants.
Topics: Humans; Infant Nutritional Physiological Phenomena; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1966 |
The metabolism of myosin and the meromyosins from rabbit skeletal muscle.
Topics: Animals; Arginine; Chromatography, Ion Exchange; In Vitro Techniques; Lysine; Muscle Proteins; Phenylalanine; Rabbits; Tyrosine | 1966 |
Quantitative microspectrophotometric analysis of nucleic acids in concentrated solutions, in solid droplets and in lymphocytes.
Topics: Animals; Cattle; DNA; Lymphocytes; Mice; Phenylalanine; RNA; Solutions; Spectrophotometry; Tryptophan; Tyrosine | 1966 |
Polyamide layer chromatography of DNP-amino acids.
Topics: Alanine; Amides; Arginine; Aspartic Acid; Chromatography; Dinitrophenols; Glutamates; Glycine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Role of the carboxyl group in intestinal amino acid transport.
Topics: Acids; Adipates; Amino Acids; Animals; Biological Transport, Active; Cricetinae; Glutamates; Glycine; In Vitro Techniques; Intestine, Small; Phenylalanine; Pimelic Acids; Sulfinic Acids; Sulfonic Acids; Tryptophan; Tyrosine | 1966 |
Influence of anabolic hormones on phenylalanine metabolism. I. Studies on chronic phenylketonuric patients.
Topics: Alanine Transaminase; Anabolic Agents; Aspartate Aminotransferases; Body Weight; Chlorpromazine; Chorionic Gonadotropin; Growth Hormone; Humans; Nandrolone; Nitrogen; Phenylalanine; Phenylketonurias; Tyrosine | 1966 |
Influence of anabolic hormones on phenylalanine metabolism. II. Studies in animals.
Topics: Anabolic Agents; Animals; Body Weight; Brain Chemistry; Growth Hormone; Liver; Phenylalanine; Rabbits; Tyrosine | 1966 |
Production of coumarins by Phytophthora infestans.
Topics: Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Coumarins; Fluorescence; Fungi; Phenylalanine; Spectrophotometry; Tyrosine | 1966 |
Aromatic Cotton effects induced by cu(II) coordination.
Topics: Chemical Phenomena; Chemistry, Physical; Copper; Dipeptides; Peptides; Phenylalanine; Spectrum Analysis; Tyrosine; Vasopressins | 1966 |
A chymotrypsin-like protease from the rat submandibular gland.
Topics: Amino Acids; Anilides; Animals; Calcium Chloride; Chemical Phenomena; Chemistry; Chromatography; Chromatography, Gel; Chymotrypsin; Electrophoresis; Hydrazines; Hydrogen-Ion Concentration; Male; Molecular Weight; Naphthalenes; Peptide Hydrolases; Phenylalanine; Rats; Submandibular Gland; Tyrosine | 1966 |
Tryptophan: a feedback activator for chorismate mutase from Neurospora.
Topics: Enzymes; Feedback; Kinetics; Ligases; Neurospora; Phenylalanine; Phosphotransferases; Tryptophan; Tyrosine | 1966 |
Genetic control of the uptake of amino acids in Neurospora.
Topics: Amino Acids; Arginine; Cysteine; Enzyme Repression; Enzymes; Genes; Histidine; Leucine; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Tryptophan; Tyrosine; Valine | 1966 |
Sepiapterin reductase.
Topics: Animals; In Vitro Techniques; Liver; Mixed Function Oxygenases; Oxidoreductases; Phenylalanine; Pterins; Rats; Tetrahydrofolate Dehydrogenase; Tyrosine | 1966 |
An analysis of melanogenesis in differentiating pigment cells of ascidian embryos.
Topics: Amino Acids; Animals; Autoradiography; Brain; Carbon Isotopes; Cell Differentiation; Chloramphenicol; Insecta; Leucine; Melanins; Phenylalanine; Phenylthiourea; Puromycin; Tyrosine; Valine | 1966 |
Nuclear histones and early embryogenesis of the chick.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Autoanalysis; Cell Differentiation; Cell Division; Cell Nucleus; Chick Embryo; Electrophoresis; Glutamates; Glycine; Histidine; Histones; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1966 |
Retention of deuterium in p-tyrosine formed enzymatically from p-deuterophenylalanine.
Topics: Benzoates; Deuterium; Magnetic Resonance Spectroscopy; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Spectrum Analysis; Tyrosine | 1966 |
Analysis of N-methylamino acids by automatic amino acid analyzer and gas-liquid chromatography.
Topics: Alanine; Anti-Bacterial Agents; Arginine; Aspartic Acid; Autoanalysis; Chromatography, Gas; Cysteine; Cystine; Glutamates; Glycine; Indicators and Reagents; Isoleucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1966 |
The production of meta-tritiotyrosine from p-tritiophenylalanine by phenylalanine hydroxylase.
Topics: Animals; Chromatography, Paper; Dihydroxyphenylalanine; In Vitro Techniques; Liver; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Pyrrolidinones; Rats; Tritium; Tyrosine | 1966 |
[Isolation and characterization of a chloramphenicol-destroying bacterium].
Topics: Carbon; Chloramphenicol; Flavobacterium; Nitrogen; Peptones; Phenylalanine; Soil Microbiology; Tryptophan; Tyrosine; Yeasts | 1966 |
The preparation of pure [I-14-C]- and [I-3-H]-labeled L-amino acids.
Topics: Alanine; Amino Acids; Aminobutyrates; Carbon Isotopes; Chemistry, Organic; Chromatography; Glycine; Isoleucine; Leucine; Optics and Photonics; Organic Chemistry Phenomena; Phenylalanine; Tritium; Tyrosine; Valine | 1966 |
[Composition of the amino acid pool of Neurospora in deficiency of growth substance].
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Biotin; Choline; Chromatography, Ion Exchange; Culture Media; Glutamates; Glycine; Growth Inhibitors; Lysine; Methionine; Mutation; Neurospora; Phenylalanine; Pyridoxine; Riboflavin; Serine; Threonine; Tyrosine; Valine | 1966 |
Action of water-insoluble trypsin derivatives on fibrinogen clottability.
Topics: Anhydrides; Animals; Blood Coagulation; Blood Coagulation Tests; Cattle; Electrophoresis; Ethylenes; Fibrinogen; Leucine; Maleates; Phenylalanine; Polymers; Thrombin; Trypsin; Tyrosine; Ultracentrifugation | 1966 |
[The effect of preliminary short wave ultraviolet irradiation on the luminescence of certain biological objects stimulated by long wave ultraviolet irradiation].
Topics: Amino Acids; Animals; Blood; Cartilage; Cattle; Fluorescence; Glycerol; Humans; Male; Microscopy, Fluorescence; Phenylalanine; Radiation Effects; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
[A study of the initial photochemical processes in proteins. IV. Luminescence spectra of initial and final photoproducts of aromatic amino acids and proteins].
Topics: Amino Acids; Fluorescence; Hot Temperature; Hydrogen-Ion Concentration; Indoles; Phenylalanine; Propionates; Proteins; Ribonucleases; Spectrum Analysis; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays | 1966 |
[Chromatographic investigation of free amino acids of the heart, kidneys and brain in experimental myocarditis].
Topics: Alanine; Amino Acids; Animals; Arginine; Asparagine; Brain; Chromatography, Paper; Cystine; Glutamine; Glycine; Histidine; Kidney; Lysine; Methionine; Myocarditis; Myocardium; Phenylalanine; Rabbits; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1966 |
Metabolism of radioactive phenylalanine in rats with different dietary intakes of phenylalanine.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Diet; Humans; Male; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1966 |
The hydrolysis of phenylalanine methyl ester by bovine thrombin.
Topics: Animals; Calcium; Cattle; Cellulose; Chromatography; Chymotrypsin; Citrates; Factor V; Phenylalanine; Phospholipids; Prothrombin; Thrombin; Trypsin Inhibitors; Tyrosine | 1966 |
Free amino acids of human foetal and adult liver.
Topics: Adult; Alanine; Amino Acids; Aspartic Acid; Autoanalysis; Cystine; Female; Fetus; Glutamates; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Pregnancy; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1966 |
[Specific substance in the urine of patients with collagen disease with special reference to collagen disease and phenylalanine and tyrosine metabolism].
Topics: Chromatography, Paper; Collagen Diseases; Humans; Phenylacetates; Phenylalanine; Tyrosine | 1966 |
[An attempt at the use of autoradiography for the study of the chemical composition of cellular structures (experiments using the oocytes of the frog)].
Topics: Adenine; Amino Acids; Animals; Anura; Asparagine; Autoradiography; Carbon Isotopes; Female; Glutamates; Glycine; Histocytochemistry; Leucine; Methionine; Methods; Nucleosides; Ovum; Phenylalanine; Tritium; Tyrosine | 1966 |
Tryptophan deficiency in rabbit reticulocytes: polyribosomes during interrupted growth of hemoglobin chains.
Topics: Animals; Deficiency Diseases; Hemoglobins; Histidine; Leucine; Lysine; Phenylalanine; Rabbits; Reticulocytes; Ribosomes; Serine; Tryptophan; Tyrosine; Valine | 1967 |
Hyperphenylalanemia without phenylketonuria.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Body Height; Body Weight; Diagnosis, Differential; Diet Therapy; Female; Growth; Humans; Infant; Infant, Newborn; Intellectual Disability; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
Treatment of phenylketonuria.
Topics: Bone Development; Child, Preschool; Diet Therapy; Electroencephalography; Female; Growth; Humans; Infant; Intelligence Tests; Male; Neurologic Examination; Phenylacetates; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
Dietary treatment in tyrosinemia (tyrosinosis). With a note on the possible recognition of the carrier state.
Topics: Amino Acid Metabolism, Inborn Errors; Carrier State; Child; Child, Preschool; Diet Therapy; Female; Growth; Humans; Kidney Diseases; Kidney Tubules; Male; Mixed Function Oxygenases; Phenylacetates; Phenylalanine; Seizures; Tyrosine | 1967 |
Dietary treatment of tyrosinosis.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Diet Therapy; Female; Growth; Humans; Infant; Kidney Diseases; Kidney Tubules; Liver Cirrhosis; Methionine; Mixed Function Oxygenases; Phenylalanine; Phosphorus; Rickets; Tyrosine | 1967 |
Clinical observations on phenylketonuria.
Topics: Adolescent; Adult; Child; Child, Preschool; Diet Therapy; Female; Humans; Infant; Infant, Newborn; Intelligence Tests; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
The early treatment of phenylketonuria.
Topics: Body Height; Body Weight; Child, Preschool; Diet Therapy; Female; Growth; Humans; Hunger; Infant; Infant, Newborn; Intelligence Tests; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
Changes in the amino acid composition of proteolipids of white matter during maturation of the human nervous system.
Topics: Adult; Aged; Amino Acids; Aspartic Acid; Central Nervous System; Child; Frontal Lobe; Humans; Infant; Infant, Newborn; Leucine; Lipoproteins; Maple Syrup Urine Disease; Phenylalanine; Proline; Tyrosine | 1967 |
Composition and mass of peptides released during tryptic and chymotryptic hydrolysis of myosin.
Topics: Arginine; Chromatography, Gel; Chymotrypsin; Kinetics; Lysine; Muscle Proteins; Peptides; Phenylalanine; Proline; Trypsin; Tyrosine | 1967 |
Phenylketonuria. 3. Measurement of multiple parameters of liver function.
Topics: Bilirubin; Cholesterol; Clinical Enzyme Tests; Humans; Isocitrate Dehydrogenase; Liver Function Tests; Methionine; Phenylalanine; Phenylketonurias; Thymol; Transaminases; Tyrosine; Vitamin B 12 | 1967 |
Rate constants of hydrated electron reactions with peptides and proteins.
Topics: Alanine; Albumins; Asparagine; Electrons; Gelatin; Glycine; Histidine; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Weight; Muramidase; Peptides; Phenylalanine; Proline; Proteins; Ribonucleases; Tryptophan; Tyrosine; Valine | 1967 |
Further studies of amino acid transport by embryonic chick bone.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport, Active; Bone and Bones; Chick Embryo; Dactinomycin; Ethylmaleimide; Glycine; In Vitro Techniques; Isoleucine; Leucine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Amino acid esters as inhibitors of growth and of aminoacyl transfer ribonucleic acid synthetases in Euglena and Astasia.
Topics: Alanine; Amino Acids; Antimetabolites; Aspartic Acid; Cysteine; Esters; Euglena; Eukaryota; Glutamates; Hydrogen-Ion Concentration; Leucine; Ligases; Methionine; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 1967 |
Amino acid imbalance and liver glycogen changes in rats fed glycine.
Topics: Amino Acids; Animals; Biological Transport; Body Weight; Carbohydrate Metabolism; Diet; Glycine; Liver Glycogen; Male; Phenylalanine; Protein Biosynthesis; Rats; Stress, Physiological; Tyrosine | 1967 |
Rabbit thyroid metabolism in tissue and organ culture.
Topics: Animals; Culture Techniques; Female; Iodides; Iodine Isotopes; Phenylalanine; Rabbits; Thyroid Gland; Tyrosine | 1967 |
The effect of excess L-phenylalamine on mothers and on their breast-fed infants.
Topics: Breast Feeding; Female; Humans; Infant; Infant Nutritional Physiological Phenomena; Male; Milk, Human; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
Phenylketonuria in rats: a model for biochemical studies.
Topics: Amino Acids; Animals; Carbon Isotopes; Humans; Male; Models, Theoretical; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1967 |
Amino-acid replacements in horse haemoglobin.
Topics: Amino Acid Sequence; Animals; Chromatography, Paper; Electrophoresis; Glutamine; Hemoglobins; Horses; Lysine; Phenylalanine; Tyrosine | 1967 |
Pathology of amino acid excess. VII. Phenylalanine and tyrosine.
Topics: Animals; Blood Cell Count; Blood Urea Nitrogen; Body Weight; Diet; Epididymis; Epiphyses; Hematocrit; Hemoglobinometry; Liver; Male; Organ Size; Pancreas; Phenylalanine; Rats; Skin; Thymus Gland; Tyrosine | 1967 |
A new developing solvent for paper chromatography of various phenolic compounds, sugars and amino acids.
Topics: Amino Acids; Anthocyanins; Arginine; Asparagine; Carbohydrates; Chromatography, Paper; Gallic Acid; Glutamates; Histidine; Indicators and Reagents; Leucine; Lysine; Methionine; Phenols; Phenylalanine; Phloroglucinol; Proline; Resorcinols; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Phenylalanine as substrate and inhibitor of tyrosine hydroxylase.
Topics: Adrenal Medulla; Animals; Cattle; Caudate Nucleus; Dihydroxyphenylalanine; Dogs; Enzymes; Guinea Pigs; In Vitro Techniques; Kinetics; Mixed Function Oxygenases; Myocardium; Phenylalanine; Tyrosine | 1967 |
Reactions in frozen systems. VI. Ice as a possible model for biological structured-water systems.
Topics: Acetylcholine; Asparagine; Catalysis; Chemical Phenomena; Chemistry; Copper; Cytosine; Dioxins; Glutamates; Glutamine; Glycine; Hydroxylamines; Ice; Imidazoles; Kinetics; Models, Theoretical; Nitrates; Phenylalanine; Piperazines; Potassium Chloride; Pyrazoles; Serine; Tyrosine | 1967 |
Optical rotatory dispersion of some aromatic amino acids and peptides.
Topics: Chemical Phenomena; Chemistry, Physical; Glycine; Peptides; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1967 |
The possible role of thyroid aromatic amino acid decarboxylase in thyroxine biosynthesis.
Topics: Animals; Carbon Isotopes; Carboxy-Lyases; Cattle; Diiodotyrosine; Histidine; In Vitro Techniques; Phenylalanine; Pyridoxal Phosphate; Thyroid Gland; Thyroxine; Tryptophan; Tyrosine | 1967 |
The recovery of amino acids from acid hydrolysates of whole urine from patients with thermal burns.
Topics: Alanine; Amino Acids; Ammonia; Arginine; Aspartic Acid; Burns; Creatine; Glutamates; Glycine; Histidine; Humans; Hydroxyproline; Isoleucine; Leucine; Lysine; Ornithine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine; Urea; Valine | 1967 |
[The metabolism of L-, D- and DL-phenylalanine by the rat].
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Electrophoresis; Injections, Intravenous; Male; Phenylalanine; Phenylpyruvic Acids; Protein Biosynthesis; Rats; Tyrosine | 1967 |
The effect of phenylalanine analogues on the metabolism of tyrosine in rats.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Injections, Intravenous; Male; Phenylalanine; Protein Biosynthesis; Rats; Respiration; Tyrosine | 1967 |
The influence of norepinephrine on the distribution of radioactivity from some of its 14C-labeled analogues and precursors.
Topics: Animals; Biological Transport; Brain; Carbon Isotopes; Chlorpromazine; Chromatography, Paper; Kidney; Leucine; Liver; Lysine; Male; Myocardium; Norepinephrine; Phenylalanine; Propylamines; Rats; Serotonin; Tyramine; Tyrosine | 1967 |
The metabolism of aromatic compounds with different side chains by a pseudomonas.
Topics: Benzoates; Butyrates; Gentisates; Hydrogen-Ion Concentration; Keto Acids; Phenylacetates; Phenylalanine; Propionates; Pseudomonas; Tyrosine; Valerates | 1967 |
Phenylalanine hydroxylase from Pseudomonas species (ATCC 11299a). Purification of the enzyme and activation by various metal ions.
Topics: Cadmium; Chemical Phenomena; Chemistry; Chromatography; Copper; Hot Temperature; Iron; Mercury; Mixed Function Oxygenases; Molecular Weight; Oxygen; Phenylalanine; Pseudomonas; Pteridines; Tyrosine | 1967 |
Plasma amino acid pattern of chicks in relation to length of feeding period.
Topics: Amino Acids; Animals; Appetite Regulation; Arginine; Birds; Cystine; Dietary Proteins; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Threonine; Tyrosine; Valine | 1967 |
Effect of fasting and of feeding a nonprotein diet on plasma amino acid levels in the chick.
Topics: Amino Acids; Animals; Arginine; Birds; Cystine; Diet; Dietary Proteins; Fasting; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Threonine; Tyrosine; Valine | 1967 |
Electron microscopic and biochemical characterization of collagen in blattarian insects.
Topics: Alanine; Ammonia; Animals; Arginine; Aspartic Acid; Collagen; Connective Tissue Cells; Cysteine; Cystine; Female; Glutamates; Glycine; Histidine; Histocytochemistry; Hydroxyproline; Insecta; Isoleucine; Leucine; Lysine; Male; Methionine; Microscopy, Electron; Phenylalanine; Proline; Serine; Threonine; Tyrosine; Valine | 1967 |
Biosynthesis of mesembrine. The incorporation of one-carbon units and the origin of the C6 unit.
Topics: Alkaloids; Carbon Isotopes; Methionine; Phenylalanine; Plants, Medicinal; Tyrosine | 1967 |
Rapid short-column chromatography of amino acids. A method for blood and urine specimens in the diagnosis and treatment of metabolic disease.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Amino Acids; Aminobutyrates; Autoanalysis; Buffers; Chromatography, Ion Exchange; Citrates; Cysteine; Cystine; Glutamates; Glutamine; Glycine; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Isoleucine; Phenylalanine; Proline; Sarcosine; Serine; Threonine; Tyrosine; Valine | 1967 |
Gluconeogenesis from amino acids in neonatal rat liver.
Topics: Alanine; Alanine Transaminase; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartate Aminotransferases; Aspartic Acid; Gluconeogenesis; Glutamates; Glycine; Histidine; In Vitro Techniques; Leucine; Liver; Liver Glycogen; Phenylalanine; Proline; Rats; Serine; Spectrophotometry; Threonine; Tyrosine; Valine | 1967 |
Intra- and intermolecular factors affecting the excited states of aromatic amino acids.
Topics: Acetates; Amides; Cinnamates; Energy Transfer; Fluorescence; Hydrochloric Acid; Hydrogen-Ion Concentration; Luminescent Measurements; Phenols; Phenylalanine; Sodium Chloride; Sodium Hydroxide; Spectrophotometry; Tryptophan; Tyramine; Tyrosine | 1967 |
The enzymatic deficiency in tyrosinemia.
Topics: Amino Acid Metabolism, Inborn Errors; Humans; Infant; Oxidoreductases; Phenylalanine; Tyrosine | 1967 |
Observations on treatment in patients with tyrosyluria.
Topics: Amino Acid Metabolism, Inborn Errors; Diet Therapy; Humans; Infant; Phenylalanine; Tyrosine | 1967 |
Natriferic and hydro-osmotic effects on the toad bladder of vasopressin analogues with selective antidiuretic activity.
Topics: Animals; Anura; Arginine; Biological Transport; In Vitro Techniques; Osmosis; Phenylalanine; Pituitary Hormones, Posterior; Sodium; Tyrosine; Urinary Bladder; Vasopressins; Water; Water-Electrolyte Balance | 1967 |
Meta-carboxy-substituted aromatic amino acids in plant metabolism. 3.
Topics: Acetates; Amino Acids; Benzoates; Carbon Dioxide; Carbon Isotopes; Chromatography, Paper; Cinnamates; Glucose; Glycine; Magnoliopsida; Methionine; Phenylalanine; Shikimic Acid; Tyrosine | 1967 |
Aromatic amino acid biosynthesis in Trichophyton rubrum. I. Phenylalanine and tyrosine biosynthesis.
Topics: Carbon Isotopes; Culture Media; Glucose; Phenylalanine; Trichophyton; Tyrosine | 1967 |
Metabolism of some meta-carboxy aromatic amino acids.
Topics: Benzoates; Carbon Isotopes; Chromatography, Paper; Phenylalanine; Plants; Tyrosine | 1967 |
Phenylalanine hydroxylase in tumor-bearing animals.
Topics: Adrenal Glands; Adrenalectomy; Animals; Carcinoma 256, Walker; Liver; Liver Regeneration; Male; Oxidoreductases; Phenylalanine; Rats; Sarcoma, Experimental; Tryptophan; Tyrosine | 1967 |
Phenylalanine hydroxylase activity in isolated, perfused liver of rats bearing rhodamine sarcoma, hepatoma, and nodular hyperplasia.
Topics: Animals; Carcinoma 256, Walker; Hyperplasia; In Vitro Techniques; Liver; Liver Diseases; Liver Regeneration; Male; Oxidoreductases; Perfusion; Phenylalanine; Rats; Sarcoma, Experimental; Tryptophan; Tyrosine | 1967 |
Effect of limiting concentrations of T1 ribonuclease on the release of aminoacyl-oligonucleotides from unfractionated yeast acceptor RNA.
Topics: Alanine; Amino Acids; Cellulose; Chromatography, Ion Exchange; Glycine; Guanine Nucleotides; Phenylalanine; Ribonucleases; RNA, Transfer; Tyrosine; Yeasts | 1967 |
The interrelation of hypothermia and depletion of noradrenaline, dopamine and 5-hydroxytryptamine from brain by reserpine, para-chlorophenylalanine and alpha-methylmetatyrosine.
Topics: Animals; Body Temperature; Brain Chemistry; Bretylium Compounds; Dopamine; Guanethidine; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Norepinephrine; Phenoxybenzamine; Phenylalanine; Rats; Reserpine; Serotonin; Tyrosine | 1967 |
Tyrosine hydroxylase inhibitors. Synthesis and activity of substituted aromatic amino acids.
Topics: Adrenal Glands; Animals; Carbon Isotopes; Cattle; In Vitro Techniques; Oxidoreductases; Phenylalanine; Pteridines; Tyrosine | 1967 |
Metabolic traits in mentally retarded children as compared with normal populations: Phenylalanine and tyrosine in serum and urine.
Topics: Adolescent; Child; Child, Preschool; Chromatography; Female; Humans; Intellectual Disability; Male; Phenylalanine; Tyrosine | 1967 |
A study of the mode of action of chloramphenicol on the chick morphogenesis.
Topics: Abnormalities, Drug-Induced; Aminobenzoates; Animals; Chick Embryo; Chloramphenicol; Heart Defects, Congenital; Lactates; Microcephaly; Nervous System Malformations; Phenylalanine; Tyrosine | 1967 |
The effect of high phenylalanine concentration on the formation of DOPA from phenylalanine and tyrosine by tyrosine hydroxylase.
Topics: Dihydroxyphenylalanine; Mixed Function Oxygenases; Phenylalanine; Tyrosine | 1967 |
Excitation, dissipative, and emissive mechanisms in biochemicals.
Topics: Absorption; Electrons; Fluorescence; Phenylalanine; Quantum Theory; Radiation Effects; Spectrum Analysis; Temperature; Trypsin; Tryptophan; Tyrosine | 1967 |
Differences between the chemical structures of duck and hen egg-white lysozymes.
Topics: Amino Acid Sequence; Animals; Arginine; Chickens; Chromatography, Ion Exchange; Ducks; Egg White; Histidine; Leucine; Lysosomes; Phenylalanine; Tyrosine | 1967 |
[Regulation of the biosynthesis of aromatic amino acids in Saccharomyces cerevisiae. 2. Repression, induction and activation].
Topics: Enzyme Induction; Enzyme Repression; Hydro-Lyases; Isomerases; Ligases; Phenylalanine; Saccharomyces; Tryptophan; Tyrosine | 1967 |
Chromatographic analysis of free amino acids of gastric juice in patients with cancer and other stomach diseases.
Topics: Adult; Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Cystine; Duodenal Ulcer; Female; Gastric Juice; Glutamates; Histidine; Humans; Leucine; Lysine; Male; Methionine; Ornithine; Phenylalanine; Polyps; Stomach Diseases; Stomach Neoplasms; Stomach Ulcer; Threonine; Tryptophan; Tyrosine; Valine | 1967 |
Determination of heterozygosity for phenylketonuria on the amino acid analyzer.
Topics: Autoanalysis; Buffers; Child; Heterozygote; Humans; Methods; Middle Aged; Phenylalanine; Phenylketonurias; Tyrosine | 1967 |
The effect of progesterone on the concentration of plasma amino acids in man.
Topics: Acromegaly; Alanine; Amino Acids; Arginine; Citrulline; Cystine; Fasting; Glycine; Histidine; Humans; Isoleucine; Leucine; Liver; Lysine; Methionine; Ornithine; Phenylalanine; Progesterone; Proline; Proteins; Threonine; Tyrosine; Valine | 1967 |
Yield of luminescence from x-irradiated biochemicals.
Topics: Amino Acids; Enzymes; Luminescent Measurements; Muramidase; Phenylalanine; Radiation Effects; Radiochemistry; Radiometry; Ribonucleases; Spectrum Analysis; Trypsin; Tryptophan; Tyrosine; Ultraviolet Rays | 1967 |
p-Chlorophenylalanine-induced chemical manifestations of phenylketonuria in rats.
Topics: Animals; Brain Chemistry; Humans; Liver; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 1967 |
The effect of phenylalanine administration on the activities of phenylalanine hydroxylase, some aminotransferases and decarboxylases in adult rats.
Topics: Animals; Brain; Carboxy-Lyases; Chromatography, Paper; Dopa Decarboxylase; Female; Humans; Injections, Intraperitoneal; Kidney; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Rats; Transaminases; Tryptophan; Tyrosine | 1967 |
Dietary induction of hyperphenylalaninemia in the rat.
Topics: Animals; Body Weight; Diet; Female; Growth; Humans; Liver; Mortality; Oxidoreductases; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy, Animal; Rats; Tryptophan; Tyrosine | 1967 |
A simple radioisotope assay for phenylalanine hydroxylase.
Topics: Animals; Brain; Buffers; Clinical Enzyme Tests; Fluorometry; Guinea Pigs; Iodine; Liver; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Pyrrolidinones; Rats; Tissue Extracts; Tritium; Tyrosine | 1967 |
Presence of N-acetyl group in hyaluronidase.
Topics: Alanine; Amino Acids; Animals; Cattle; Chromatography, Ion Exchange; Chromatography, Thin Layer; Glutamates; Hyaluronoglucosaminidase; Hydrazines; Leucine; Male; Peptides; Phenylalanine; Testis; Tyrosine | 1967 |
Some biochemical consequences of feeding excesses of phenylalanine to rats.
Topics: Animals; Brain Chemistry; Humans; Learning; Liver; Mixed Function Oxygenases; Organ Size; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Proteins; Rats; Tyrosine | 1967 |
Effects of amino acid loads on a health infant with the biochemical features of Hartnup disease.
Topics: Amino Acids; Hartnup Disease; Histidine; Humans; Infant, Newborn; Intestinal Absorption; Kidney Function Tests; Lysine; Male; Nicotinic Acids; Phenylalanine; Tyrosine | 1967 |
Tyrosine metabolism in patients with liver disease.
Topics: Adult; Alkaline Phosphatase; Ammonia; Biliary Tract Diseases; Bilirubin; Glutamate Dehydrogenase; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Liver Function Tests; Phenylalanine; Portacaval Shunt, Surgical; Serum Albumin; Sulfobromophthalein; Tyrosine | 1967 |
[Transamination between amino acids and alpha-ketoglutaric acid in the carp].
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cyprinidae; Glutamates; In Vitro Techniques; Intestinal Mucosa; Isoleucine; Ketoglutaric Acids; Leucine; Liver; Lysine; Ornithine; Perfusion; Phenylalanine; Transaminases; Tyrosine; Valine | 1967 |
Selective alteration by triiodothyronine of amino acid transport in embryonic bone.
Topics: Amino Acids; Animals; Biological Transport; Bone and Bones; Chick Embryo; Glycine; Histidine; Leucine; Methionine; Phenylalanine; Triiodothyronine; Tryptophan; Tyrosine; Valine | 1967 |
Degradion of phenylalanine and tyrosine by Basidiomycetes.
Topics: Basidiomycota; Carbon Isotopes; Phenylalanine; Tyrosine | 1967 |
Infusion of branched chain amino acids after partial hepatectomy in man.
Topics: Amino Acids; Amino Acids, Branched-Chain; Ammonia; Carcinoma, Hepatocellular; Female; Hepatectomy; Humans; Infusions, Parenteral; Kinetics; Liver Diseases; Liver Neoplasms; Male; Methionine; Middle Aged; Phenylalanine; Tyrosine | 1984 |
The need of essential amino acids in children. An evaluation based on the intake of phenylalanine, tyrosine, leucine, isoleucine, and valine in children with phenylketonuria, tyrosine amino transferase defect, and maple syrup urine disease.
Topics: Amino Acids, Essential; Child; Child, Preschool; Dietary Proteins; Female; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Nutritional Requirements; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Tyrosine; Tyrosine Transaminase; Valine | 1980 |
Enzymological basis for growth inhibition by L-phenylalanine in the cyanobacterium Synechocystis sp. 29108.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Allosteric Regulation; Cyanobacteria; Hydro-Lyases; Mutation; Phenylalanine; Prephenate Dehydratase; Tyrosine | 1980 |
Regulatory control of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthetase in Streptomyces antibioticus.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Chorismic Acid; Enzyme Repression; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Streptomyces; Streptomyces antibioticus; Tryptophan; Tyrosine | 1980 |
Effect of enzyme concentration on regulation of dissociable chorismate mutase in Brevibacterium flavum.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Brevibacterium; Chorismate Mutase; Feedback; Isomerases; Kinetics; Molecular Weight; Phenylalanine; Polyethylene Glycols; Potassium Chloride; Tryptophan; Tyrosine | 1981 |
Regulatory isozymes of 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase in the cyanobacterium Anabaena sp. strain ATCC 29151.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Cyanobacteria; Isoenzymes; Molecular Weight; Phenylalanine; Tyrosine | 1981 |
Serotonin and dopamine synthesis in phenylketonuria.
Topics: Dopamine; Humans; Kinetics; Phenylalanine; Phenylketonurias; Serotonin; Tryptamines; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 1981 |
Biochemical study of malnutrition. Part V. Metabolism of phenylalanine and tyrosine.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adult; Democratic Republic of the Congo; Female; Humans; Phenylalanine; Phenylalanine Hydroxylase; Protein-Energy Malnutrition; Tyrosine; Tyrosine Transaminase | 1981 |
False neurotransmitters and hepatic failure.
Topics: Hemodynamics; Humans; Liver Diseases; Octopamine; Phenylalanine; Tyrosine | 1982 |
Conversion of chloramphenicol degradation products by tyrosine aminotransferase from Flavobacteria.
Topics: Chloramphenicol; Flavobacterium; Kinetics; Phenylalanine; Substrate Specificity; Tyrosine; Tyrosine Transaminase | 1982 |
[Problems of protein supply in patients with liver cirrhosis].
Topics: Ammonia; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Methionine; Neurotransmitter Agents; Parenteral Nutrition; Phenylalanine; Proteins; Tryptophan; Tyrosine; Urea | 1982 |
[Inhibition of L-tyrosine transport in isolated synaptosomes from rat brain in the presence of L-tryptophan and L-phenylalanine].
Topics: Animals; Binding, Competitive; Biological Transport, Active; Brain; Carrier Proteins; Female; Male; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Inbred Strains; Synaptosomes; Tryptophan; Tyrosine | 1982 |
Regulation of the aromatic pathway in the cyanobacterium Synechococcus sp. strain Pcc6301 (Anacystis nidulans).
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Cyanobacteria; Enzyme Activation; Genes, Regulator; Hydro-Lyases; Mutation; Phenylalanine; Prephenate Dehydratase; Tyrosine | 1983 |
Hidden overflow pathway to L-phenylalanine in Pseudomonas aeruginosa.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Genes, Bacterial; Genes, Regulator; p-Fluorophenylalanine; Phenylalanine; Prephenate Dehydratase; Pseudomonas aeruginosa; Tyrosine | 1983 |
Effect of aspartame loading on plasma and erythrocyte free amino acid concentrations in one-year-old infants.
Topics: Adult; Age Factors; Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Erythrocytes; Glutamates; Glutamic Acid; Humans; Infant; Phenylalanine; Tyrosine | 1983 |
Abnormal amino acid concentrations in plasma and urine of experimentally diabetic dogs.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Arginine; Diabetes Mellitus, Experimental; Dogs; Female; Glutamates; Glutamic Acid; Histidine; Male; Phenylalanine; Renal Aminoacidurias; Tryptophan; Tyrosine | 1983 |
Tyrosine supplementation in chronic experimental uremia.
Topics: Animals; gamma-Glutamyltransferase; Growth; Kidney; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Tyrosine; Uremia | 1983 |
Impact of isozymes upon partitioning of carbon flow and regulation of aromatic biosynthesis in prokaryotes.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Bacteria; Chorismate Mutase; Cyanobacteria; Genes; Genes, Bacterial; Genes, Regulator; Isoenzymes; Mutation; Phenylalanine; Pseudomonas; Pseudomonas aeruginosa; Transaminases; Tryptophan; Tyrosine | 1983 |
The nucleotide sequence of the aroF gene of Escherichia coli and the amino acid sequence of the encoded protein, the tyrosine-sensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Amino Acid Sequence; Base Sequence; DNA Restriction Enzymes; Escherichia coli; Genes; Operon; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Tyrosine | 1984 |
Correction of altered plasma amino acid pattern in cirrhosis of the liver by somatostatin.
Topics: Amino Acids; Amino Acids, Branched-Chain; C-Peptide; Glucagon; Humans; Insulin; Liver Cirrhosis, Alcoholic; Male; Phenylalanine; Somatostatin; Tyrosine | 1984 |
The aromatic amino acid pathway branches at L-arogenate in Euglena gracilis.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Amino Acids; Amino Acids, Dicarboxylic; Animals; Biological Evolution; Cyclohexenes; Euglena gracilis; Hydro-Lyases; Lyases; Oxidoreductases; Phenylalanine; Phosphorus-Oxygen Lyases; Prephenate Dehydrogenase; Shikimic Acid; Transaminases; Tyrosine | 1981 |
Dipolar NMR relaxation of nonprotonated aromatic carbons in proteins. Structural and dynamical effects.
Topics: Animals; Aprotinin; Carbon; Cattle; Crystallography; Magnetic Resonance Spectroscopy; Mathematics; Phenylalanine; Protein Conformation; Tyrosine | 1982 |
Sensitivity of tryptophan, tyrosine and phenylalanine mutants of Saccharomyces cerevisiae to phenethyl alcohol.
Topics: Ethanol; Mutation; Phenylalanine; Phenylethyl Alcohol; Saccharomyces cerevisiae; Species Specificity; Tryptophan; Tyrosine | 1983 |
Successful dietary control of tyrosinemia II.
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Corneal Opacity; Female; Humans; Keratins; Keratoderma, Palmoplantar; Phenylacetates; Phenylalanine; Phenylpropionates; Phenylpyruvic Acids; Syndrome; Tyrosine; Tyrosine Transaminase | 1983 |
Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.
Topics: Amino Acid Sequence; Animals; Gramicidin; Ion Channels; Mathematics; Models, Biological; Models, Molecular; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1984 |
Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles.
Topics: Amino Acids; Animals; Aspartame; Brain; Dipeptides; Drug Interactions; Glucose; Hydroxyindoleacetic Acid; Male; Phenylalanine; Rats; Rats, Inbred Strains; Serotonin; Tyrosine | 1984 |
A mutation at the major phosphotyrosine in pp60v-src alters oncogenic potential.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oncogene Protein pp60(v-src); Phenylalanine; Phosphotyrosine; Protein Kinases; Tyrosine; Viral Proteins | 1984 |
Effect of amino acid metabolites on lysosomal protein degradation. A regulatory role for kynurenine?
Topics: alpha-Fetoproteins; Amino Acids; Animals; Asialoglycoproteins; Fetuins; Histidine; In Vitro Techniques; Kynurenine; Liver; Male; Microscopy, Electron; Phenylalanine; Proteins; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1984 |
A study of placental transfer mechanisms in nonhuman primates using [14C]phenylalanine.
Topics: Animals; Carbon Radioisotopes; Female; Fenclonine; Fetal Blood; Macaca fascicularis; Macaca mulatta; Maternal-Fetal Exchange; Phenylalanine; Pregnancy; Tyrosine | 1982 |
An in vivo function of glucagon-induced phenylalanine: pyruvate transaminase in p-chlorophenylalanine-treated rats.
Topics: Enzyme Induction; Fenclonine; Glucagon; Lactates; Liver; Phenylacetates; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Transaminases; Tyrosine | 1982 |
Isolation and structure determination of a novel spiro-gamma-lactam, spiro-arogenate.
Topics: Amino Acids, Dicarboxylic; Chemical Phenomena; Chemistry; Circular Dichroism; Cyclohexenes; Hot Temperature; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neurospora; Neurospora crassa; Phenylalanine; Pyrrolidinones; Pyrrolidonecarboxylic Acid; Tyrosine | 1983 |
Dietary management of oculocutaneous tyrosinemia in an 11-year-old child.
Topics: Adolescent; Adult; Ambulatory Care; Child; Child, Preschool; Female; Humans; Infant; Intellectual Disability; Keratitis; Keratoderma, Palmoplantar; Male; Phenylalanine; Seasons; Syndrome; Tyrosine | 1983 |
Nuclear-magnetic-resonance studies of eukaryotic cytochrome c. Assignment of resonances of aromatic amino acids.
Topics: Amino Acids; Animals; Cytochrome c Group; Fishes; Histidine; Horses; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Rabbits; Species Specificity; Tryptophan; Tyrosine | 1980 |
Conformational changes of hemoproteins as evidenced by second derivative spectroscopy of aromatic amino acids.
Topics: Adult; Amino Acids; Animals; Cytochrome c Group; Cytochrome P-450 Enzyme System; Hemoglobins; Humans; Male; Microsomes, Liver; Phenylalanine; Protein Conformation; Rabbits; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1980 |
In vitro energy costs of Na+, K+ATPase activity and protein synthesis in muscle from calves differing in age and breed.
Topics: Aging; Animals; Cattle; Culture Techniques; Male; Muscle Proteins; Muscles; Oxygen Consumption; Phenylalanine; Sodium-Potassium-Exchanging ATPase; Species Specificity; Tyrosine | 1982 |
Structure and heme environment of ferrocytochrome c553 from 1H NMR studies.
Topics: Cyanobacteria; Cytochrome c Group; Heme; Histidine; Magnetic Resonance Spectroscopy; Methionine; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1982 |
Structural role of the tyrosine residues of cytochrome c.
Topics: Amino Acid Sequence; Animals; Cytochrome c Group; Homoserine; Horses; Leucine; Magnetic Resonance Spectroscopy; Neurospora crassa; Phenylalanine; Protein Conformation; Temperature; Tuna; Tyrosine | 1982 |
Transformation by polyoma virus is drastically reduced by substitution of phenylalanine for tyrosine at residue 315 of middle-sized tumor antigen.
Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Base Sequence; Cell Transformation, Viral; Cells, Cultured; Codon; Kidney; Mice; Mutation; Phenylalanine; Polyomavirus; Protein Kinases; RNA, Messenger; Tyrosine; Viral Proteins | 1984 |
Effect of experimental diabetes on the levels of aromatic and branched-chain amino acids in rat blood and brain.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood-Brain Barrier; Brain; Diabetes Mellitus, Experimental; Dietary Proteins; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine; Valine | 1983 |
Fast kinetic study of yeast phenylalanyl-tRNA synthetase: an efficient discrimination between tyrosine and phenylalanine at the level of the aminoacyladenylate-enzyme complex.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Kinetics; Phenylalanine; Phenylalanine-tRNA Ligase; Saccharomyces cerevisiae; Substrate Specificity; Tyrosine | 1983 |
Effects of vitamin D metabolites on protein catabolism of muscle from uremic rats.
Topics: Alanine; Animals; Calcifediol; Calcitriol; Insulin; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine; Uremia | 1983 |
Genetic instability associated with the aroC321 allele in Salmonella typhimurium involves genetic duplication.
Topics: Chromosome Mapping; Chromosomes, Bacterial; Genes, Bacterial; Lyases; Phenylalanine; Phosphorus-Oxygen Lyases; Salmonella typhimurium; Tryptophan; Tyrosine | 1983 |
Effects of insulin on cardiac lysosomes and protein degradation.
Topics: Acetylglucosaminidase; Amino Acids; Animals; Cathepsin D; Cathepsins; In Vitro Techniques; Insulin; Lysosomes; Microscopy, Electron; Myocardium; Perfusion; Phenylalanine; Proteins; Rats; Tyrosine; Vacuoles | 1984 |
Fast kinetic study of yeast phenylalanyl-tRNA synthetase: role of tRNAPhe in the discrimination between tyrosine and phenylalanine.
Topics: Amino Acyl-tRNA Synthetases; Kinetics; Mathematics; Oxidation-Reduction; Phenylalanine; Phenylalanine-tRNA Ligase; RNA, Transfer, Amino Acyl; Saccharomyces cerevisiae; Structure-Activity Relationship; Tyrosine | 1984 |
Plasma amino acid imbalance in alcoholic liver cirrhosis.
Topics: Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Glucagon; Humans; Insulin; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Phenylalanine; Tyrosine | 1984 |
Nucleotide sequence and transcription of the phenylalanine and tyrosine operons of Escherichia coli K12.
Topics: Amino Acid Sequence; Base Sequence; Codon; DNA, Bacterial; Escherichia coli; Genes; Operon; Phenylalanine; Plasmids; Protein Biosynthesis; Terminator Regions, Genetic; Transcription, Genetic; Tyrosine | 1984 |
Small intestinal absorption of amino acids and a dipeptide in pancreatic insufficiency.
Topics: Amino Acids; Child; Child, Preschool; Dipeptides; Humans; Infant; Intestinal Absorption; Intestine, Small; Lysine; Pancreatic Diseases; Phenylalanine; Tyrosine | 1983 |
Investigation of some amino acid analogues and metabolites as inhibitors of wool and hair growth.
Topics: Animals; Cycloleucine; Cystine; Ethionine; Glutathione; Hair; Lysine; Methionine; Mice; Phenylalanine; Sheep; Tyrosine; Wool | 1983 |
Potent inhibitory effects of tyrosine metabolites on dihydropteridine reductase from human and sheep liver.
Topics: Animals; Dihydropteridine Reductase; Dihydroxyphenylalanine; Humans; NADH, NADPH Oxidoreductases; Phenylacetates; Phenylalanine; Phenylpropionates; Phenylpyruvic Acids; Rats; Sheep; Tyramine; Tyrosine | 1984 |
Encephalopathy, oxygen consumption, visceral amino acid clearance, and mortality in cirrhotic surgical patients.
Topics: Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Ammonia; Female; Hemodynamics; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Octopamine; Oxygen Consumption; Phenylalanine; Tyrosine | 1984 |
Dihydropteridine reductase deficiency: non-response to oral tetrahydrobiopterin load test.
Topics: Biopterins; Female; Fibroblasts; Humans; Infant; Lymphocytes; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1984 |
Effects of branched chain amino acids on spontaneous growth hormone secretion in the baboon.
Topics: Amino Acids, Branched-Chain; Animals; Eating; Growth Hormone; Isoleucine; Leucine; Lysine; Male; Papio; Phenylalanine; Time Factors; Tyrosine; Valine | 1984 |
A mild case of dihydropteridine reductase deficiency with residual activity in erythrocytes.
Topics: Biopterins; Dihydropteridine Reductase; Erythrocytes; Female; Follow-Up Studies; Humans; Infant, Newborn; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylketonurias; Tyrosine | 1984 |
Induction of an experimental phenylketonuria-like condition in infant rats during the first 2 weeks after birth.
Topics: Animals; Animals, Newborn; Diet; Disease Models, Animal; Female; Fenclonine; Humans; Male; Methotrexate; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Tyrosine | 1981 |
The influence of starvation and tryptophan administration on the metabolism of phenylalanine, tyrosine and tryptophan in isolated rat liver cells.
Topics: Amino Acids; Animals; In Vitro Techniques; Liver; Male; Phenylalanine; Rats; Rats, Inbred Strains; Starvation; Tryptophan; Tyrosine | 1984 |
Absolute dependence of phenylalanine and tyrosine biosynthetic enzyme on tryptophan in Candida maltosa.
Topics: Candida; Chorismate Mutase; Chromatography, DEAE-Cellulose; Fungal Proteins; Hydro-Lyases; Kinetics; Phenylalanine; Prephenate Dehydrogenase; Tryptophan; Tyrosine | 1984 |
Nuclear magnetic resonance analyses of side chain conformations of histidine and aromatic amino acid derivatives. Solvent and pH dependence.
Topics: Histidine; Hydrogen-Ion Concentration; Indicators and Reagents; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Solvents; Structure-Activity Relationship; Tryptophan; Tyrosine | 1984 |
Determination of aromatic amino acids by ion-pair reversed-phase liquid chromatography in human sera from healthy and phenylketonuric individuals.
Topics: Amino Acids; Chromatography, Liquid; Histidine; Humans; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine | 1984 |
Relationship between changes in plasma amino acids and depression in alcoholic patients.
Topics: Adult; Alcoholism; Amino Acids; Brain; Depressive Disorder; Humans; Male; Middle Aged; Phenylalanine; Serotonin; Tryptophan; Tyrosine | 1984 |
The formation of m-tyrosine and o-tyrosine in rats.
Topics: Animals; Chromatography, High Pressure Liquid; Male; Phenylalanine; Rats; Rats, Inbred Strains; Time Factors; Tyrosine | 1984 |
The nutritive value and safety of D-phenylalanine and D-tyrosine in mice.
Topics: Animal Feed; Animals; Body Weight; Food, Fortified; Mice; Mice, Inbred Strains; Nutritive Value; Phenylalanine; Stereoisomerism; Tyrosine | 1984 |
Self-selection of phenylalanine in the rat.
Topics: Animals; Body Weight; Brain Chemistry; Diet; Food Preferences; Male; Nutritional Requirements; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1984 |
Phenylalanine and tyrosine requirements of immature beagle dogs.
Topics: Administration, Oral; Amino Acids, Essential; Animals; Body Weight; Diet; Dogs; Drug Interactions; Feces; Food, Formulated; Male; Nitrogen; Nutritional Requirements; Phenylalanine; Tyrosine; Urea | 1984 |
[Malignant forms of phenylketonuria].
Topics: Child; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Prognosis; Tyrosine | 1984 |
Aminoacids--precursors of melanin synthesis in hamster melanoma.
Topics: Amino Acids; Animals; Cricetinae; Ferrous Compounds; Iron; Levodopa; Male; Melanins; Melanoma; Mesocricetus; Neoplasm Transplantation; Phenylalanine; Tryptophan; Tyrosine | 1984 |
Carrier screening for phenylketonuria: comparison of two discriminant analysis procedures.
Topics: Female; Genetic Carrier Screening; Heterozygote; Homozygote; Humans; Male; Pedigree; Phenylalanine; Phenylketonurias; Tyrosine | 1984 |
[In vitro synthesis of tyrosine from phenylalanine in human platelets].
Topics: Adult; Blood Platelets; Depressive Disorder; Female; Humans; In Vitro Techniques; Male; Phenylalanine; Phenylketonurias; Schizophrenia; Tyrosine | 1984 |
The determination of flux through phenylalanine hydroxylase and homogentisate oxidase in isolated hepatocytes.
Topics: Animals; Cells, Cultured; Dioxygenases; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Kinetics; Liver; Male; Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Tyrosine | 1984 |
Analysis of 1- and 3-methylhistidines, aromatic and basic amino acids in rat and human urine.
Topics: Amino Acids; Animals; Chromatography, Ion Exchange; Histidine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Immobilization; Male; Methylhistidines; Phenylalanine; Rats; Rats, Inbred Strains; Species Specificity; Temperature; Tryptophan; Tyrosine; Ultrafiltration | 1984 |
Studies on the biosynthesis of coenzyme F420 in methanogenic bacteria.
Topics: Carbon Radioisotopes; Euryarchaeota; Flavins; Guanine; Methionine; Phenylalanine; Riboflavin; Tyrosine | 1984 |
Chymotrypsin modified with polyethylene glycol catalyzes peptide synthesis reaction in benzene.
Topics: Animals; Benzene; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Enzyme Activation; Peptide Biosynthesis; Phenylalanine; Polyethylene Glycols; Solubility; Trypsin; Tyrosine | 1984 |
Inhibition of protein and aminoacyl-tRNA synthesis, and binding and transport sites for aromatic amino acids in the brain in vitro with aromatic acids.
Topics: Amino Acids; Animals; Brain; Brain Chemistry; Cattle; Homogentisic Acid; In Vitro Techniques; Nerve Tissue Proteins; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Inbred Strains; RNA, Transfer, Amino Acyl; Synaptic Membranes; Synaptosomes; Tritium; Tryptophan; Tyrosine | 1984 |
Hyperphenylalaninemia with defective transamination.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Female; Humans; Infant; Male; Phenylalanine; Tyrosine | 1983 |
The effect of various amino acids and drugs on the para- and meta-hydroxyphenylacetic acid concentrations in the mouse caudate nucleus.
Topics: Amino Acids; Animals; Apomorphine; Caudate Nucleus; Kinetics; Male; Mice; Phenylacetates; Phenylalanine; Tyrosine | 1983 |
Effect of a branched chain amino acid-enriched nutritional product on the pathophysiology of the liver and nutritional state of patients with liver cirrhosis.
Topics: Adult; Aged; Amino Acids, Branched-Chain; Ammonia; Dietary Proteins; Evaluation Studies as Topic; Female; Food, Formulated; Humans; Liver; Liver Cirrhosis; Male; Methionine; Middle Aged; Nitrogen; Phenylalanine; Prealbumin; Tyrosine | 1983 |
Plasma amino acid ratio as an index of hepatocellular maturity in the neonate.
Topics: Amino Acids; Cholestasis; Female; Humans; Infant Food; Infant, Low Birth Weight; Infant, Newborn; Isoleucine; Leucine; Liver; Male; Phenylalanine; Tyrosine; Valine | 1983 |
The biosynthesis of p-tyramine, m-tyramine, and beta-phenylethylamine by rat striatal slices.
Topics: Animals; Corpus Striatum; Decarboxylation; In Vitro Techniques; Isomerism; Phenethylamines; Phenylalanine; Rats; Tyramine; Tyrosine | 1983 |
Effects of untreated maternal phenylketonuria and hyperphenylalaninemia on the fetus.
Topics: Abortion, Spontaneous; Birth Weight; Body Weight; Child; Child, Preschool; Congenital Abnormalities; Female; Fetal Blood; Fetus; Humans; Infant; Infant, Newborn; Intellectual Disability; Intelligence; Male; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1983 |
Iron deficiency in the rat: biochemical studies of fetal metabolism.
Topics: Animals; Diet; Female; Fetal Blood; Fetus; Iron Deficiencies; Liver; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Rats; Rats, Inbred Strains; Tyrosine | 1983 |
Comparative study of physiochemical properties of two pike parvalbumins by means of their intrinsic tyrosyl and phenylalanyl fluorescence.
Topics: Animals; Cations; Chemical Phenomena; Chemistry; Fishes; Hydrogen-Ion Concentration; Muscle Proteins; Muscles; Parvalbumins; Phenylalanine; Protein Denaturation; Spectrometry, Fluorescence; Temperature; Tyrosine; Urea | 1983 |
[Biosynthesis of phenylalanine and tyrosine in Flavobacteria].
Topics: Chemical Phenomena; Chemistry; Chorismate Mutase; Culture Media; Flavobacterium; Oxidoreductases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Tyrosine | 1983 |
Changes of serum amino acids in severely burned patients.
Topics: Adolescent; Adult; Amino Acids; Amino Acids, Branched-Chain; Burns; Cysteine; Female; Humans; Male; Methionine; Phenylalanine; Tyrosine; Urea | 1983 |
In vivo safety of hollow fiber enzyme-reactors with immobilized phenylalanine ammonia-lyase in a large animal model for phenylketonuria.
Topics: Ammonia-Lyases; Animals; Blood Cells; Blood Urea Nitrogen; Disease Models, Animal; Dogs; Enzymes, Immobilized; Female; Humans; Macaca; Male; Phenylalanine; Phenylalanine Ammonia-Lyase; Phenylketonurias; Time Factors; Tyrosine | 1983 |
Alcohol and related dietary effects on mouse natural killer-cell activity.
Topics: Alcoholism; Animals; Body Weight; Cytotoxicity, Immunologic; Diet; Female; Humans; Killer Cells, Natural; Methionine; Mice; Mice, Inbred C57BL; Phenylalanine; Tyrosine | 1983 |
[Maternal phenylketonuria].
Topics: Child; Chromatography, Thin Layer; Female; Heterozygote; Humans; Infant, Newborn; Intellectual Disability; Male; Maternal-Fetal Exchange; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1984 |
Effect of different amino acid diets on delta 5, delta 6 and delta 9 desaturases.
Topics: Amino Acids; Animals; Diet; Fatty Acid Desaturases; Female; Microsomes, Liver; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1984 |
[Dietary management of hereditary tyrosinemia. Apropos of 7 cases].
Topics: Amino Acid Metabolism, Inborn Errors; Child, Preschool; Female; Humans; Infant; Male; Methionine; Phenylalanine; Tyrosine | 1984 |
Detection of heterozygous carriers for phenylketonuria by a L-[2H5]phenylalanine stable isotope loading test.
Topics: Deuterium; Female; Genetic Carrier Screening; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1984 |
Some aspects of studies of thermal transitions in proteins by means of their intrinsic fluorescence.
Topics: Animals; Calcium; Calorimetry, Differential Scanning; Fishes; Magnesium; Muscle Proteins; Muscles; Parvalbumins; Phenylalanine; Protein Conformation; Species Specificity; Spectrometry, Fluorescence; Thermodynamics; Tryptophan; Tyrosine | 1984 |
On the brain barrier system function and changes of cerebrospinal fluid concentrations of phenylalanine and tyrosine in human phenylketonuria.
Topics: Blood-Brain Barrier; Humans; Phenylalanine; Phenylketonurias; Reference Values; Tyrosine | 1984 |
Biosynthetic studies of arphamenines A and B.
Topics: Acetates; Acetic Acid; Aminopeptidases; Animals; Arginine; Chromobacterium; Guanidines; Phenylalanine; Rats; Tyrosine | 1984 |
[Transport of phenylalanine and tyrosine in Brevibacterium linens: specificity and incorporation into proteins].
Topics: Amino Acids; Bacterial Proteins; Biological Transport; Brevibacterium; Chloramphenicol; Kinetics; Phenylalanine; Protein Biosynthesis; Tetracycline; Tyrosine | 1984 |
Impairment of blood pressure control in patients with liver cirrhosis during tilting: study on adrenergic and renin-angiotensin systems.
Topics: Adult; Blood Pressure; Female; Heart Rate; Hematocrit; Humans; Liver Cirrhosis; Male; Middle Aged; Norepinephrine; Phenylalanine; Posture; Renin; Renin-Angiotensin System; Sympathetic Nervous System; Tyrosine | 1982 |
Phenylalanine lowers melanin synthesis in mammalian melanocytes by reducing tyrosine uptake: implications for pigment reduction in phenylketonuria.
Topics: Animals; Cricetinae; Humans; Melanins; Melanocytes; Melanoma; Monophenol Monooxygenase; Neoplasms, Experimental; Phenylalanine; Phenylketonurias; Skin Neoplasms; Skin Pigmentation; Tyrosine | 1980 |
Muscle and plasma amino acids after injury: hypocaloric glucose vs. amino acid infusion.
Topics: Amino Acids; Female; Glucose; Hip Joint; Hip Prosthesis; Humans; Isoleucine; Leucine; Male; Middle Aged; Muscles; Parenteral Nutrition; Phenylalanine; Surgical Procedures, Operative; Tyrosine; Valine; Wounds and Injuries | 1980 |
Genetic control of a shared idiotype among antibodies directed to distinct specificities.
Topics: Alanine; Animals; Antibody Diversity; Antibody Specificity; Binding Sites, Antibody; Genes; Glutamates; Immune Sera; Immunoglobulin Idiotypes; Lysine; Mice; Mice, Inbred Strains; Mutation; Peptides; Phenylalanine; Proline; Tyrosine | 1980 |
Plasma amino acids in 3/sec spike-wave epilepsy.
Topics: Adolescent; Adult; Alanine; Amino Acids; Aspartic Acid; Child; Child, Preschool; Epilepsy; Female; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Male; Methionine; Middle Aged; Phenylalanine; Serine; Taurine; Threonine; Tyrosine; Valine | 1980 |
Regulation by aromatic amino acids of the biosynthesis of candicidin by Streptomyces griseus.
Topics: Antifungal Agents; Candicidin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Phenylalanine; Streptomyces griseus; Time Factors; Tryptophan; Tyrosine | 1980 |
Regulation of aromatic amino acid biosynthesis in Escherichia coli K-12: control of the aroF-tyrA operon in the absence of repression control.
Topics: Amino Acids; Enzyme Repression; Escherichia coli; GTP Pyrophosphokinase; Ketoses; Operon; Phenylalanine; Sugar Phosphates; Tryptophan; Tyrosine | 1980 |
Plasma and cerebrospinal fluid amino acid concentrations in phenylketonuria during the newborn period.
Topics: Amino Acids; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Phenylketonurias; Threonine; Tyrosine | 1981 |
Intracellular concentrations of phenylalanine, tyrosine and alpha-aminobutyric acid in 13 homozygotes and 19 heterozygotes for phenylketonuria compared with 26 normals.
Topics: Aminobutyrates; Child; Child, Preschool; Female; Heterozygote; Homozygote; Humans; Infant; Lymphocytes; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1981 |
Pathogenesis of hepatic encephalopathy and hyperdynamic syndrome in cirrhosis. Role of false neurotransmitters.
Topics: Adolescent; Adult; Aged; Amino Acids; Cardiac Output; Female; Hemodynamics; Hepatic Encephalopathy; Humans; Liver Cirrhosis, Alcoholic; Male; Middle Aged; Octopamine; Phenylalanine; Syndrome; Tryptophan; Tyrosine; Vascular Resistance | 1981 |
Thiol compounds. III Synthesis and antihypertensive activity of mercaptoacylamino acids.
Topics: Amino Acids; Animals; Antihypertensive Agents; Dihydroxyphenylalanine; Methyldopa; Phenylalanine; Sulfhydryl Compounds; Tyrosine | 1981 |
Results of screening for phenylalanine and other amino acid disturbances among pregnant women.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids; Female; Humans; Male; Pedigree; Phenylalanine; Pregnancy; Pregnancy Complications; Tyrosine | 1980 |
Alteration in plasma amino acid concentrations following subtotal hepatectomy in dogs.
Topics: Amino Acids; Animals; Dogs; Female; Hepatectomy; Hepatic Encephalopathy; Isoleucine; Leucine; Male; Methionine; Phenylalanine; Threonine; Tyrosine; Valine | 1981 |
Genetic basis of pigmentation and its disorders.
Topics: Albinism; Animals; Cell Differentiation; Color; Humans; Lentigo; Melanins; Melanocytes; Melanoma; Mice; Monophenol Monooxygenase; Nevus; Phenylalanine; Pigmentation; Pigmentation Disorders; Skin; Syndrome; Tyrosine | 1981 |
Behavioural and biochemical effects of tryptophan, tyrosine and phenylalanine in mice.
Topics: Amino Acids; Animals; Biogenic Amines; Brain Chemistry; Male; Mice; Mice, Inbred Strains; Motor Activity; Phenylalanine; Swimming; Tryptophan; Tyrosine | 1982 |
Regulation of pancreatic protein synthesis by cholecystokinin and calcium.
Topics: Animals; Calcium; Cholecystokinin; Diabetes Mellitus, Experimental; Egtazic Acid; Kinetics; Male; Pancreas; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tyrosine | 1982 |
The use of deuterated phenylalanine for the in vivo assay of phenylalanine hydroxylase activity in children.
Topics: Child; Child, Preschool; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Infant; Phenylalanine; Phenylalanine Hydroxylase; Time Factors; Tyrosine | 1982 |
Effect of zinc deficiency on appetite and free amino acid concentrations in rat brain.
Topics: Amino Acids; Animals; Appetite; Brain; Eating; Male; Phenylalanine; Rats; Tryptophan; Tyrosine; Zinc | 1983 |
Sodium ascorbate enhancement of carbidopa-levodopa methyl ester antitumor activity against pigmented B16 melanoma.
Topics: Animals; Antineoplastic Agents; Ascorbic Acid; Carbidopa; Cell Line; Diet; Drug Synergism; Drug Therapy, Combination; Female; Injections, Intraperitoneal; Levodopa; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1983 |
Acute effects of aspartame on large neutral amino acids and monoamines in rat brain.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Aspartame; Brain; Catecholamines; Dipeptides; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1983 |
A simplified PKU gene carrier detection test using fasting blood.
Topics: Fasting; Genetic Carrier Screening; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1983 |
Newborn phenylalanine/tyrosine metabolism. Implications for screening for phenylketonuria.
Topics: Aging; Fetal Blood; Humans; Infant, Newborn; Infant, Newborn, Diseases; Mass Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1983 |
Phenylalanine and tyrosine levels in newborn screening blood samples.
Topics: Birth Weight; Bottle Feeding; Breast Feeding; Female; Humans; Infant Food; Infant, Newborn; Male; Mass Screening; Phenylalanine; Residence Characteristics; Tyrosine | 1983 |
Evaluation of the PaT Stat Kinetic UV Test set for the determination of phenylalanine and tyrosine in serum or plasma.
Topics: Adult; Evaluation Studies as Topic; Humans; Kinetics; Phenylalanine; Reagent Kits, Diagnostic; Spectrophotometry, Ultraviolet; Tyrosine | 1983 |
Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic mixture of L- and D-phenylalanine.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Humans; Hydroxylation; Kinetics; Mass Spectrometry; Nitrogen Isotopes; Phenylalanine; Stereoisomerism; Tyrosine | 1983 |
[Biosynthesis of phenylalanine and tyrosine: arogenic acid, a new intermediate product].
Topics: Amino Acids, Dicarboxylic; Bacteria; Cyclohexenes; Hydro-Lyases; Oxidoreductases; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Species Specificity; Tyrosine | 1983 |
Plasma phenylalanine, tyrosine, and tryptophan in schizophrenia.
Topics: Administration, Oral; Adult; Heterozygote; Humans; Infusions, Parenteral; Phenylalanine; Phenylketonurias; Schizophrenia; Tryptophan; Tyrosine | 1983 |
Circular dichroism spectroscopy of the intermediates that precede the rate-limiting step of the refolding pathway of bovine pancreatic trypsin inhibitor. Relationship of conformation and the refolding pathway.
Topics: Animals; Cattle; Circular Dichroism; Disulfides; Kinetics; Phenylalanine; Protein Conformation; Trypsin Inhibitor, Kazal Pancreatic; Trypsin Inhibitors; Tyrosine | 1983 |
[Biosynthesis of phenylalanine and tyrosine in Streptomycetes].
Topics: Feedback; Kinetics; Phenylalanine; Species Specificity; Streptomyces; Tyrosine | 1983 |
Alkaptonuria.
Topics: Alkaptonuria; Dietary Proteins; Humans; Male; Middle Aged; Phenylalanine; Tyrosine | 1983 |
Partial alleviation of phenylalanine toxicity in the chick by supplemental dietary tryptophan.
Topics: Animals; Body Weight; Brain; Chickens; Depression, Chemical; Diet; Male; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine | 1983 |
The contribution of phenylalanine to tyrosine metabolism in vivo. Studies in the post-absorptive and phenylalanine-loaded rat.
Topics: Amino Acids; Animals; Kinetics; Leucine; Male; Oxidation-Reduction; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine | 1983 |
[Problems posed by maternal phenylketonuria].
Topics: Brain; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tryptophan; Tyrosine | 1983 |
Selective killing of transformed cells by methotrexate with histidine deprivation or with alpha-amino alcohols.
Topics: Animals; Cell Division; Cell Survival; Histidine; Histidinol; Imidazoles; Methotrexate; Mice; Mice, Inbred BALB C; Phenylalanine; Tyrosine | 1983 |
Transport of aromatic amino acids by Brevibacterium linens.
Topics: 2,4-Dinitrophenol; Biological Transport, Active; Brevibacterium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dinitrophenols; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Phenylalanine; Temperature; Tryptophan; Tyrosine | 1983 |
Deficiency in homogentisic acid oxidase activity associated with the brown phenotype of Dictyostelium discoideum.
Topics: Dictyostelium; Dioxygenases; Genotype; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Mutation; Oxygenases; Phenotype; Phenylalanine; Pigmentation; Ploidies; Suppression, Genetic; Tyrosine | 1983 |
Tyrosine supplementation during pregnancy in a woman with classical phenylketonuria. A case report.
Topics: Female; Humans; Infant, Newborn; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1983 |
Inhibition by L-phenylalanine of tyrosine transport by synaptosomal plasma membrane vesicles: implications in the pathogenesis of phenylketonuria.
Topics: Animals; Biological Transport; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Rats; Rats, Inbred Strains; Synaptic Vesicles; Synaptosomes; Tyrosine | 1982 |
Studies on the mechanism of NK cell lysis.
Topics: Animals; Arginine; Calcium; Carbamates; Cytotoxicity, Immunologic; Dose-Response Relationship, Immunologic; Female; Immunity, Cellular; Indoles; Male; Mice; Mice, Inbred CBA; Nitrobenzoates; Phenylalanine; Phenylcarbamates; Protease Inhibitors; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Tubercidin; Tyrosine | 1982 |
Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?
Topics: Animals; Cycloheximide; Diaphragm; Kinetics; Leucine; Male; Muscle, Smooth; Myocardium; Phenylalanine; Protein Biosynthesis; Proteins; Rats; RNA, Transfer, Amino Acyl; Tyrosine | 1982 |
Convergence and minimal mutation criteria for evaluating early events in tRNA evolution.
Topics: Animals; Base Sequence; Biological Evolution; Eukaryotic Cells; Glycine; Mutation; Phenylalanine; Phylogeny; Prokaryotic Cells; RNA, Transfer; Species Specificity; Tyrosine; Valine | 1980 |
Cord-blood tyrosine levels in the full-term phenylketonuric fetus and the "justification hypothesis".
Topics: Female; Fetal Blood; Humans; Infant, Newborn; Intellectual Disability; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1980 |
Evaluation of the relative potency of individual competing amino acids to tryptophan transport in endogenously depressed patients.
Topics: Adult; Aged; Amino Acids; Binding, Competitive; Biological Transport; Depressive Disorder; Female; Humans; Isoleucine; Leucine; Middle Aged; Phenylalanine; Tryptophan; Tyrosine; Valine | 1980 |
Protein dynamics by solid-state NMR: aromatic rings of the coat protein in fd bacteriophage.
Topics: Coliphages; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine; Viral Proteins | 1982 |
HPLC analysis of aromatic amino acids, nucleosides, and bases in plasma of acute lymphocytic leukemia on chemotherapy.
Topics: Adenosine; Amino Acids; Chromatography, High Pressure Liquid; Guanosine; Humans; Hypoxanthines; Inosine; Leukemia, Lymphoid; Nucleosides; Phenylalanine; Tyrosine; Xanthines | 1982 |
Plasma phenylalanine: tyrosine ratios during high-dose methotrexate-citrovorum "rescue".
Topics: Adolescent; Bone Neoplasms; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Phenylalanine; Time Factors; Tyrosine | 1982 |
Lack of effect of a behaviorally active dose of cholecystokinin octapeptide upon aromatic amino acid levels in plasma and brain.
Topics: Amino Acids; Animals; Behavior, Animal; Brain; Cholecystokinin; Insulin; Male; Peptide Fragments; Phenylalanine; Rats; Tryptophan; Tyrosine | 1980 |
Effect of spontaneous portal-systemic shunting on plasma insulin and amino acid concentrations.
Topics: Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; C-Peptide; Female; Glucose Tolerance Test; Humans; Hypertension, Portal; Insulin; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Portal System; Tyrosine | 1980 |
Purification and thermal stability of several amino acid-specific tRNAs from an extreme thermophile, Thermus thermophilus HB8.
Topics: Codon; Drug Stability; Escherichia coli; Isoleucine; Kinetics; Nucleic Acid Denaturation; Phenylalanine; Ribonucleosides; Ribosomes; RNA, Transfer; RNA, Transfer, Amino Acyl; Species Specificity; Thermus; Tyrosine | 1980 |
Isolation and characterization of an Escherichia coli K-12 mutant defective in tyrosine- and phenylalanine-specific transport systems.
Topics: Biological Transport, Active; Chromosome Mapping; Chromosomes, Bacterial; Escherichia coli; Genes; Mutation; Phenylalanine; Tyrosine | 1980 |
Binding of regulatory nucleotides to aspartate transcarbamylase: nuclear magnetic resonance studies of selectively enriched carbon-13 regulatory subunit.
Topics: Adenosine Triphosphate; Aspartate Carbamoyltransferase; Binding Sites; Cytidine Triphosphate; Cytosine Nucleotides; Enzyme Activation; Escherichia coli; Histidine; Macromolecular Substances; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Binding; Tyrosine | 1980 |
Regulation of aromatic amino acid transport by tRNA: role of 2-methylthio-N6-(delta2-isopentenyl)-adenosine.
Topics: Adenosine; Anticodon; Biological Transport; Escherichia coli; Isopentenyladenosine; Kinetics; Mutation; Phenylalanine; RNA, Transfer; Sulfides; Tryptophan; Tyrosine | 1981 |
Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines.
Topics: Animals; Bacterial Vaccines; Drug Resistance, Microbial; Mice; Mice, Inbred C57BL; Mutation; Phenylalanine; Salmonella typhimurium; Species Specificity; Tetracycline; Transduction, Genetic; Tryptophan; Tyrosine | 1981 |
Age-related alterations in cardiac protein turnover.
Topics: Aging; Animals; Heart; In Vitro Techniques; Insulin; Kinetics; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Tyrosine | 1981 |
Metabolic effects of septicaemia in newborn and young infants with particular reference to the plasma free amino acids.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Bacterial Infections; Escherichia coli Infections; Glycine; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Phenylalanine; Proline; Pseudomonas Infections; Sepsis; Tyrosine | 1980 |
[Catecholamine and renin-angiotensin system in blood pressure control in patients with liver cirrhosis].
Topics: Adult; Blood Pressure; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Norepinephrine; Phenylalanine; Posture; Renin; Renin-Angiotensin System; Tyrosine | 1981 |
19F nuclear magnetic resonance studies of the coat protein of bacteriophage M13 in synthetic phospholipid vesicles and deoxycholate micelles.
Topics: Coliphages; Fluorine; In Vitro Techniques; Magnetic Resonance Spectroscopy; Membranes, Artificial; Micelles; Phenylalanine; Phospholipids; Tyrosine; Viral Proteins | 1982 |
Amino acid supply to individual cerebral structures in awake and anesthetized rats.
Topics: Amino Acids; Anesthesia, General; Animals; Autoradiography; Blood-Brain Barrier; Brain; Computers; Kinetics; Male; Mathematics; Phenylalanine; Rats; Tissue Distribution; Tyrosine; Wakefulness | 1982 |
Diagnosis of phenylalanine hydroxylase deficiency (phenylketonuria).
Topics: Biopsy, Needle; Child; Child, Preschool; Female; Humans; Infant; Intelligence; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1982 |
Liquid-chromatographic direct determination of phenylalanine and tyrosine in serum or plasma, with application to patients with phenylketonuria.
Topics: Chromatography, High Pressure Liquid; Humans; Phenylalanine; Phenylketonurias; Reference Values; Spectrophotometry, Ultraviolet; Tyrosine | 1982 |
Nutrition in pregnancy of women with hyperphenylalaninemia.
Topics: Abortion, Spontaneous; Congenital Abnormalities; Female; Fetal Death; Fetal Growth Retardation; Humans; Intellectual Disability; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1982 |
[First report on behaviour of phenylalanine and tyrosine in serum of patients with gynaecological carcinomas (author's transl)].
Topics: Adult; Aged; Amino Acids; Chromatography; Female; Genital Neoplasms, Female; Humans; Middle Aged; Phenylalanine; Tyrosine | 1982 |
Treatment of phenylketonuria during pregnancy.
Topics: Adult; Diet; Female; Follow-Up Studies; Heart Defects, Congenital; Humans; Infant; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1982 |
Availability of phenylalanine and tyrosine for brain norepinephrine synthesis in developmentally protein-malnourished rats.
Topics: Animals; Blood Proteins; Body Weight; Brain; Brain Chemistry; Female; Norepinephrine; Organ Size; Phenylalanine; Protein Deficiency; Rats; Serum Albumin; Tyrosine | 1982 |
Quantitation of aromatic residues in proteins: model compounds for second-derivative spectroscopy.
Topics: Chemical Phenomena; Chemistry; Guanidines; Humans; Melitten; Phenylalanine; Serum Albumin; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1982 |
Dietary influence of tyrosine and phenylalanine on the response of B16 melanoma to carbidopa-levodopa methyl ester chemotherapy.
Topics: Animals; Carbidopa; Diet; Drug Evaluation, Preclinical; Female; Levodopa; Melanoma; Mice; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1982 |
Off-line combination of liquid chromatography and field desorption mass spectrometry: principles and environmental, medical and pharmaceutical applications.
Topics: Barbiturates; Carbamates; Chromatography, High Pressure Liquid; Cyclophosphamide; Humans; Mass Spectrometry; Phenylalanine; Phenylurea Compounds; Reference Values; Thiocarbamates; Tyrosine | 1982 |
The effect of some precursor amino acids and enzyme inhibitors on the mouse striatal concentration of tyramines and homovanillic acid.
Topics: Animals; Brocresine; Corpus Striatum; Homovanillic Acid; Male; Mice; Pargyline; Phenylacetates; Phenylalanine; Tyramine; Tyrosine | 1982 |
Intracellular phenylalanine and tyrosine concentration in homozygotes and heterozygotes for phenylketonuria (PKU) and hyperphenylalaninemia compared with normals.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Female; Heterozygote; Homozygote; Humans; Infant, Newborn; Lymphocytes; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1982 |
Plasma amino acid pattern in phenylketonuric heterozygotes during pregnancy.
Topics: Adult; Amino Acids; Female; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Pregnancy Trimester, First; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Tyrosine | 1982 |
Characteristics change in serum amino acid levels in different types of hepatic encephalopathy.
Topics: Adolescent; Adult; Amino Acids; Amino Acids, Branched-Chain; Female; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Tyrosine | 1982 |
Multifunctional control of amino acids of deprivation-induced proteolysis in liver. Role of leucine.
Topics: Amino Acids; Animals; Hydrolysis; Keto Acids; Leucine; Liver; Male; Perfusion; Phenylalanine; Proteins; Rats; Tyrosine | 1982 |
Arogenate (pretyrosine) pathway of tyrosine and phenylalanine biosynthesis in Pseudomonas aureofaciens ATCC 15926.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; NAD; NADP; Oxidoreductases; Phenylalanine; Prephenate Dehydrogenase; Pseudomonas; Tyrosine | 1982 |
Liquid-chromatographic measurement of phenylalanine and tyrosine in serum.
Topics: Centrifugation; Chromatography, High Pressure Liquid; Deamination; Humans; Microcomputers; Phenylalanine; Phenylalanine Ammonia-Lyase; Spectrophotometry; Tyrosine | 1982 |
The conversion of phenylalanine to tyrosine in man. Direct measurement by continuous intravenous tracer infusions of L-[ring-2H5]phenylalanine and L-[1-13C] tyrosine in the postabsorptive state.
Topics: Absorption; Adult; Carbon Isotopes; Deuterium; Humans; Infusions, Parenteral; Isotope Labeling; Male; Phenylalanine; Tyrosine | 1982 |
Reduction of cerebrospinal fluid phenylalanine after oral administration of valine, isoleucine, and leucine.
Topics: Administration, Oral; Adult; Amino Acids, Branched-Chain; Child; Female; Humans; Infant; Infant, Newborn; Isoleucine; Leucine; Phenylalanine; Phenylketonurias; Tyrosine; Valine | 1982 |
The state of tyrosine and phenylalanine residues in proteins analyzed by fourth-derivative spectrophotometry. Histone H1 and ribonuclease A.
Topics: Animals; Cattle; Chemical Phenomena; Chemistry; Endoribonucleases; Histones; Pancreas; Phenylalanine; Ribonuclease, Pancreatic; Solvents; Spectrophotometry, Ultraviolet; Thymus Gland; Tyrosine | 1982 |
Stability decrease of RNA double helices by phenylalanine-, tyrosine- and tryptophane-amides. Analysis in terms of site binding and relation to melting proteins.
Topics: Chemical Phenomena; Chemistry; Kinetics; Phenylalanine; Poly A-U; Poly I-C; Protein Denaturation; Structure-Activity Relationship; Temperature; Tryptophan; Tyrosine | 1982 |
[Pathogenesis of cerebral dysfunction in phenylketonuria].
Topics: Brain; Catecholamines; Humans; Ketone Bodies; Myelin Proteins; Phenylalanine; Phenylketonurias; Serotonin; Tyrosine | 1982 |
[Effect of aromatic amino acids on levorin biosynthesis].
Topics: Amino Acids; Antifungal Agents; Candicidin; Culture Media; Phenylalanine; Streptomyces; Tryptophan; Tyrosine | 1982 |
Plasma phenylalanine and tyrosine levels during the day in normal female controls and female obligate phenylketonuria heterozygotes.
Topics: Female; Genetic Carrier Screening; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1982 |
Complete assignment of the 1H NMR spectrum of the aromatic residues of lysozyme.
Topics: Animals; Chickens; Egg White; Female; Histidine; Magnetic Resonance Spectroscopy; Models, Molecular; Muramidase; Phenylalanine; Protein Conformation; Quail; Tryptophan; Tyrosine | 1982 |
Fluorescence and circular-dichroism properties of pig intestinal calcium-binding protein (Mr=9000), a protein with a single tyrosine residue.
Topics: Animals; Apoproteins; Binding Sites; Calcium-Binding Proteins; Circular Dichroism; Hydrogen-Ion Concentration; Intestinal Mucosa; Phenylalanine; Spectrometry, Fluorescence; Swine; Tyrosine | 1982 |
Modulation of cerebral catecholamine concentrations during hyperphenylalaninaemia.
Topics: Animals; Brain; Dopamine; Female; Kinetics; Male; Norepinephrine; Phenylalanine; Rats; Tyrosine | 1982 |
[Intracellular concentration of phenylalanine, tyrosine and alpha-amino butyric acid in 13 homozygotes and 19 heterozygotes for phenylketonuria (PKU) compared with 26 normals (author's transl)].
Topics: Aminobutyrates; Female; Heterozygote; Homozygote; Humans; Infant, Newborn; Lymphocytes; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1980 |
Levels of free amino acids in lactating women following ingestion of the sweetener aspartame.
Topics: Adult; Aspartame; Dipeptides; Female; Humans; Lactation; Lactose; Phenylalanine; Pregnancy; Tyrosine | 1980 |
An assay for activity of arogenate dehydratase base upon the selective oxidation of arogenate.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; Hydro-Lyases; Oxidation-Reduction; Phenylalanine; Potassium Permanganate; Spectrometry, Fluorescence; Tyrosine | 1981 |
Effect of pyrrolizidine alkaloid-induced hepatic disease on plasma amino acid patterns in the horse.
Topics: 2-Aminoadipic Acid; Amino Acids; Ammonia; Animals; Horse Diseases; Horses; Isoleucine; Leucine; Liver Diseases; Male; Phenylalanine; Plant Poisoning; Plants, Toxic; Pyrrolizidine Alkaloids; Senecio; Tyrosine; Valine | 1980 |
Molecular stability of Hb Philly (alpha 2 beta 2 35(Cl) Tyr leads to Phe). Rhe relationship of hemoglobin stability to ligand state as defined by heat and mechanical shaking tests.
Topics: Drug Stability; Erythrocytes; Hemoglobin A; Hemoglobin, Sickle; Hemoglobins, Abnormal; Hot Temperature; Humans; Oxyhemoglobins; Phenylalanine; Protein Denaturation; Tyrosine | 1981 |
Lead poisoning and the blood-brain barrier.
Topics: Animals; Blood-Brain Barrier; Brain; Female; Lead Poisoning; Permeability; Phenylalanine; Rats; Tyrosine | 1981 |
Amino acid losses during CAPD.
Topics: Adult; Amino Acids; Chronic Disease; Female; Glomerulonephritis; Humans; Hypertension, Malignant; IgA Vasculitis; Male; Middle Aged; Peritoneal Dialysis; Phenylalanine; Pyelonephritis; Time Factors; Tyrosine | 1980 |
Plasma and erythrocyte concentrations of free amino acids in adult humans administered abuse doses of aspartame.
Topics: Adult; Alanine; Alanine Transaminase; Amino Acids; Aspartame; Aspartate Aminotransferases; Dipeptides; Erythrocytes; Female; Humans; Male; Phenylalanine; Plasma; Tyrosine | 1981 |
On the renal tubular damage in hereditary tyrosinemia and on the formation of succinylacetoacetate and succinylacetone.
Topics: Acetoacetates; Amino Acid Metabolism, Inborn Errors; Aminolevulinic Acid; Child; Heptanoates; Homogentisic Acid; Humans; Infant; Keto Acids; Kidney Diseases; Kidney Tubules; Male; Phenylalanine; Proteinuria; Tyrosine | 1981 |
Use of aromatic amino acids as monitors of protein turnover.
Topics: Aerobiosis; Anaerobiosis; Animals; Carbon Radioisotopes; Glucose; Kinetics; Male; Mitochondria, Heart; Phenylalanine; Proteins; Rats; Transaminases; Tritium; Tyrosine | 1981 |
Plasma tryptophan and five other amino acids in depressed and normal subjects.
Topics: Amino Acids; Depressive Disorder; Female; Humans; Isoleucine; Leucine; Male; Phenylalanine; Psychiatric Status Rating Scales; Tryptophan; Tyrosine; Valine | 1981 |
Unsuccessful treatment of phenylketonuria with tyrosine.
Topics: Adult; Child Development; Female; Food, Fortified; Humans; Infant, Newborn; Intellectual Disability; Intelligence Tests; Male; Neurologic Manifestations; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1981 |
[Nutritional habits of children with portosystemic anastomoses--effects on serum ammonia and amino acid level].
Topics: Adolescent; Adult; Amino Acids; Ammonia; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Diet; Humans; Phenylalanine; Portasystemic Shunt, Surgical; Tyrosine | 1981 |
Dietary phenylalanine and tyrosine interrelationships in the Sprague-Dawley rat.
Topics: Animals; Diet; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Pyruvates; Rats; Transaminases; Tyrosine | 1981 |
Dynamics of amino acid side chains in membrane proteins by high field solid state deuterium nuclear magnetic resonance spectroscopy. Phenylalanine, tyrosine, and tryptophan.
Topics: Bacteriorhodopsins; Carotenoids; Deuterium; Halobacterium; Magnetic Resonance Spectroscopy; Membrane Proteins; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1981 |
Effect of alpha-methylphenylalanine and phenylalanine on brain polyribosomes and protein synthesis.
Topics: Animals; Brain; Centrifugation, Density Gradient; Mice; Nerve Tissue Proteins; Peptide Chain Elongation, Translational; Phenylalanine; Phenylalanine Hydroxylase; Polyribosomes; Tyrosine | 1981 |
Plasma amino acid patterns in experimental acute hepatic failure: comparison between hepatectomy and liver devascularization in pigs.
Topics: Amino Acids; Animals; Female; Hepatectomy; Ischemia; Liver; Liver Diseases; Methionine; Phenylalanine; Swine; Tryptophan; Tyrosine | 1981 |
Plasma phenylalanine levels in phenylketonuric heterozygous and normal adults administered aspartame at 34 mg/kg body weight.
Topics: Adult; Aspartame; Aspartic Acid; Dipeptides; Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias; Sex Factors; Tyrosine | 1981 |
Blood-brain transport of tryptophan and phenylalanine: effect of portacaval shunt in dogs.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Dogs; Isoleucine; Leucine; Phenylalanine; Portacaval Shunt, Surgical; Tryptophan; Tyrosine; Valine | 1981 |
Outcome of pregnancy in a phenylketonuric mother after low phenylalanine diet introduced from the ninth week of pregnancy.
Topics: Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Time Factors; Tyrosine | 1981 |
The investigation of [(4'-amino)-PHE]4-enkephalin conformation in water by the spectrofluorimetric procedure.
Topics: Endorphins; Enkephalin, Leucine; Enkephalins; Molecular Conformation; Phenylalanine; Spectrometry, Fluorescence; Tyrosine; Water | 1981 |
Structural specificity in the renal tubular transport of tyrosine.
Topics: Absorption; Amino Acids; Animals; Biological Transport, Active; Dogs; Female; Kidney Tubules, Proximal; Male; Phenylalanine; Phenylpropionates; Stereoisomerism; Structure-Activity Relationship; Tyrosine | 1981 |
Hyperphenylalaninaemia of various types among three-quarters of a million neonates tested in a screening programme.
Topics: Amino Acids; Humans; Infant Food; Infant, Newborn; London; Mass Screening; Milk Proteins; Phenylalanine; Phenylketonurias; Tyrosine | 1981 |
Nuclear magnetic resonance study on solvent dependence of side chain conformations of tyrosine and tryptophan derivatives.
Topics: Magnetic Resonance Spectroscopy; Optical Rotation; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1981 |
Aromatic amino acid incorporation into proteins in rat brain slices: influences of other amino acids affecting transport.
Topics: Amino Acids; Animals; Animals, Newborn; Biological Transport; Brain; Cycloheximide; Male; Nerve Tissue Proteins; Phenylalanine; Protein Biosynthesis; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine | 1981 |
An enzymatic assay of plasma phenylalanine and tyrosine for the detection and management of phenylketonuria.
Topics: Adolescent; Child; Female; Humans; Infant, Newborn; Male; Methods; Phenylalanine; Phenylalanine Ammonia-Lyase; Phenylketonurias; Spectrometry, Fluorescence; Tyrosine | 1981 |
Plasma amino acids as markers of liver dysfunction in cirrhotics.
Topics: Adult; Aged; Amino Acids; Ammonia; Female; Galactose; Humans; Liver; Liver Cirrhosis; Liver Function Tests; Male; Methionine; Middle Aged; Phenylalanine; Tryptophan; Tyrosine | 1981 |
Evaluation of a nation-wide neonatal metabolic screening programme in Sweden 1965-1979.
Topics: Evaluation Studies as Topic; Galactosemias; Histidine; Homocystinuria; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Mass Screening; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Sweden; Tyrosine | 1981 |
Assay for plasma free phenylalanine and tyrosine by high-pressure liquid chromatography and field desorption mass spectrometry and its application to an in vivo study of the phenylalanine hydroxylating system in man.
Topics: Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Mass Spectrometry; Phenylalanine; Tyrosine | 1981 |
The effects of surgical trauma on plasma amino acid levels in humans.
Topics: Alanine; Amino Acids; Aspartic Acid; Female; Humans; Isoleucine; Phenylalanine; Surgical Procedures, Operative; Tyrosine | 1980 |
Comparisons of ring-current shifts calculated from the crystal structure of egg white lysozyme of hen with the proton nuclear magnetic resonance spectrum of lysozyme in solution.
Topics: Computers; Magnetic Resonance Spectroscopy; Models, Molecular; Muramidase; Phenylalanine; Protein Conformation; Tyrosine; X-Ray Diffraction | 1980 |
Effects of dietary phenylalanine and tyrosine on circulating thyroid hormone levels and growth in the chick.
Topics: Animals; Body Weight; Chickens; Diet; Lysine; Male; Phenylalanine; Thyroxine; Triiodothyronine; Tyrosine; Valine | 1980 |
Nucleotide sequence of genes coding for tRNAPhe and tRNATyr from a repeating unit of X. laevis DNA.
Topics: Animals; Base Composition; Base Sequence; Cytosine; DNA; Genes; Genetic Code; Guanine; Phenylalanine; RNA, Transfer; Tyrosine; Xenopus | 1980 |
Regulation of prephenate dehydratase in Coryneform species of bacteria by L-phenylalanine and by remote effectors.
Topics: Amino Acids; Brevibacterium; Corynebacterium; Kinetics; Methionine; Oxidoreductases; Phenylalanine; Prephenate Dehydrogenase; Species Specificity; Tryptophan; Tyrosine | 1980 |
Histidine, phenylalanine-tyrosine and tryptophan requirements for growth of the young kitten.
Topics: Animals; Cats; Histidine; Nutritional Physiological Phenomena; Nutritional Requirements; Phenylalanine; Tryptophan; Tyrosine | 1980 |
Studies on the chemical nature of dialysable transfer factor. Comparison of human leukocyte dialysate and dialysates derived from human serum and from mammalian lymphoid and non-lymphoid organs.
Topics: Animals; Blood; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Thin Layer; Dialysis; Glucose; Guinea Pigs; Humans; Hydrolysis; Leukocytes; Lymphoid Tissue; Phenylalanine; Swine; Transfer Factor; Tyrosine | 1980 |
Predictor for sulfur-aromatic interactions in globular proteins.
Topics: Amino Acids, Sulfur; Chemical Phenomena; Chemistry; Phenylalanine; Proteins; Tyrosine | 1980 |
L-Tryptophan transport in human red blood cells.
Topics: Amino Acids; Biological Transport; Erythrocytes; Humans; Kinetics; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1980 |
Metabolism of aromatic amino acids by the rat heart and diaphragm.
Topics: Alanine; Alanine Transaminase; Animals; Diaphragm; In Vitro Techniques; Muscles; Myocardium; Perfusion; Phenylalanine; Rats; Transaminases; Tyrosine | 1980 |
Multitubular reactors with immobilized L-phenylalanine ammonia-lyase for use in extracorporeal shunts.
Topics: Ammonia-Lyases; Deamination; Drug Stability; Enzymes, Immobilized; Kinetics; Male; Methods; Phenylalanine; Phenylalanine Ammonia-Lyase; Rhodotorula; Temperature; Tyrosine | 1980 |
Intracellular concentrations of phenylalanine, tyrosine and alpha-aminobutyric acid in 13 homozygotes and 19 heterozygotes for phenylketonuria (PKU) compared with 26 normals.
Topics: Adult; Amino Acids; Aminobutyrates; Child; Child, Preschool; Female; Heterozygote; Homozygote; Humans; Infant; Lymphocytes; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1980 |
Rapid automated ion-exchange analysis of plasma tyrosine and phenylalanine with data print-out.
Topics: Autoanalysis; Chromatography, Ion Exchange; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1980 |
Regulation of phenylalanine and tyrosine biosynthesis in Pseudomonas aureofaciens ATCC 15926.
Topics: Chorismate Mutase; Chromatography, Gel; Chromatography, Ion Exchange; Enzyme Repression; Molecular Weight; Phenylalanine; Prephenate Dehydratase; Prephenate Dehydrogenase; Pseudomonas; Tyrosine | 1980 |
Conformational analysis of linear peptides by 15N NMR spectroscopy using the enkephalin-related fragment Tyr-Gly-Gly-Phe as a model compound.
Topics: Endorphins; Enkephalins; Glycine; Magnetic Resonance Spectroscopy; Oligopeptides; Phenylalanine; Protein Conformation; Tyrosine | 1980 |
[Growth inhibition by phenylalanine and tyrosine--metabolism of phenylalanine in Flavobacterium devorans (author's transl)].
Topics: Aminobenzoates; Dose-Response Relationship, Drug; Flavobacterium; ortho-Aminobenzoates; Phenylalanine; Tryptophan; Tyrosine | 1980 |
The diagnosis of phenylketonuria: a report from the Collaborative Study of Children Treated for Phenylketonuria.
Topics: Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1980 |
Formation of m-tyrosine and o-tyrosine from L-phenylalanine by rat brain homogenate.
Topics: Animals; Brain; In Vitro Techniques; Isomerism; Phenylalanine; Rats; Tyrosine | 1980 |
Purification and properties of dissociable chorismate mutase from Brevibacterium flavum.
Topics: Amino Acids; Brevibacterium; Chorismate Mutase; Isomerases; Kinetics; Macromolecular Substances; Molecular Weight; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1980 |
Total aromatic amino acid requirement, phenylalanine requirement and tyrosine replacement value for fingerling channel catfish.
Topics: Amino Acids; Animals; Body Weight; Dose-Response Relationship, Drug; Drug Interactions; Fishes; Nutritional Requirements; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1980 |
Second-derivative spectroscopy of proteins: studies on tyrosyl residues.
Topics: Chemical Phenomena; Chemistry; Phenylalanine; Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1980 |
Phenylalanine ammonia-lyase entrapped in fibers.
Topics: Ammonia-Lyases; Buffers; Cellulose; Enzymes, Immobilized; In Vitro Techniques; Phenylalanine; Phenylalanine Ammonia-Lyase; Temperature; Tyrosine | 1980 |
Regulation of tyrosine biosynthesis by phenylalanine in anthramycin-producing Streptomyces refuineus.
Topics: Anthramycin; Benzodiazepinones; Mutation; Phenylalanine; Streptomyces; Tyrosine | 1980 |
Maternal phenylketonuria and hyperphenylalaninemia. An international survey of the outcome of untreated and treated pregnancies.
Topics: Abortion, Spontaneous; Birth Weight; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Intellectual Disability; Intelligence; Microcephaly; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1980 |
Ultraviolet difference spectroscopy of intermediates trapped in unfolding and refolding of bovine pancreatic trypsin inhibitor.
Topics: Animals; Cattle; Cystine; Ethylene Glycols; Models, Molecular; Pancreas; Phenylalanine; Protein Conformation; Protein Denaturation; Spectrophotometry, Ultraviolet; Trypsin Inhibitors; Tyrosine | 1980 |
Prevalence of subclinical hepatic encephalopathy in cirrhotics and relationship to plasma amino acid imbalance.
Topics: Adult; Aged; Amino Acids; Amino Acids, Branched-Chain; Ammonia; Blood-Brain Barrier; Female; Hepatic Encephalopathy; Humans; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Trail Making Test; Tryptophan; Tyrosine | 1980 |
[Phenylalanine-tyrosine metabolism in psoriasis vulgaris. Search on a genetic basic defect (author's transl)].
Topics: Adult; Female; Humans; Male; Middle Aged; Phenylalanine; Psoriasis; Tyrosine | 1980 |
Membrane transport of aromatic amino acids by Hymenolepis diminuta (Cestoda).
Topics: Amino Acids; Animals; Biological Transport; Cell Membrane; Hymenolepis; Kinetics; Phenylalanine; Sodium; Tryptophan; Tyrosine | 1980 |
Liquid-chromatographic quantification of plasma phenylalanine, tyrosine, and tryptophan.
Topics: Amino Acids; Blood Chemical Analysis; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenylalanine; Tryptophan; Tyrosine | 1981 |
Metabolism of phenylalanine in liver diseases.
Topics: DNA; Humans; Kinetics; Liver Diseases; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1980 |
Aspartame administration to the infant monkey: hypothalamic morphology and plasma amino acid levels.
Topics: Amino Acids; Animals; Aspartame; Aspartic Acid; Dipeptides; Female; Glutamates; Hypothalamus; Macaca; Macaca fascicularis; Macaca mulatta; Male; Phenylalanine; Sodium Glutamate; Tyrosine | 1980 |
Intestinal transport of glucose and amino acids in experimental uremia.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Blood Urea Nitrogen; Glucose; Histidine; Intestinal Absorption; Jejunum; Male; Phenylalanine; Rats; Tyrosine; Uremia | 1980 |
Mutations of human class III alcohol dehydrogenase.
Topics: Aldehyde Oxidoreductases; Aspartic Acid; Escherichia coli; Humans; Leucine; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Tyrosine | 1995 |
Effect of the hydrophilic alpha-tocopherol analog MDL 74,405 on detection of hydroxyl radicals in stunned myocardium in dogs.
Topics: Animals; Antioxidants; Coronary Circulation; Dogs; Female; Free Radical Scavengers; Heart; Hemodynamics; Hydroxylation; Male; Myocardial Stunning; Myocardium; Phenylalanine; Tyrosine; Vitamin E | 1995 |
Nonhydrolyzable phosphotyrosyl mimetics for the preparation of phosphatase-resistant SH2 domain inhibitors.
Topics: Amino Acid Sequence; Enzyme Inhibitors; Hydrolysis; Molecular Sequence Data; Oncogene Protein pp60(v-src); Phenylalanine; Phosphoric Monoester Hydrolases; Phosphotyrosine; Tyrosine | 1994 |
Evidence for nutrient modulation of tumor phenotype: impact of tyrosine and phenylalanine restriction.
Topics: Animal Nutritional Physiological Phenomena; Animals; Diet; Female; Killer Cells, Natural; Lung; Mast Cells; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Phenotype; Phenylalanine; Tumor Cells, Cultured; Tyrosine | 1994 |
Substitutions and deletions in the cytoplasmic domain of the phagocytic receptor Fc gamma RIIA: effect on receptor tyrosine phosphorylation and phagocytosis.
Topics: Amino Acid Sequence; Animals; Antigens, CD; Cell Line; Cytoplasm; Humans; Molecular Sequence Data; Mutagenesis; Phagocytosis; Phenylalanine; Phosphorylation; Phosphotyrosine; Receptors, IgG; Structure-Activity Relationship; Transfection; Tyrosine | 1994 |
Potent inhibition of insulin receptor dephosphorylation by a hexamer peptide containing the phosphotyrosyl mimetic F2Pmp.
Topics: Amino Acid Sequence; Animals; Cell Membrane; CHO Cells; Cricetinae; Humans; Indicators and Reagents; Kinetics; Molecular Sequence Data; Oligopeptides; Phenylalanine; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor, Insulin; Recombinant Proteins; Transfection; Tyrosine | 1994 |
Pressure effects on enzyme reactions in mainly organic media: alpha-chymotrypsin in reversed micelles of Aerosol OT in octane.
Topics: Animals; Catalysis; Cattle; Chymotrypsin; Dioctyl Sulfosuccinic Acid; Hydrolysis; Micelles; Octanes; Pancreas; Phenylalanine; Pressure; Surface-Active Agents; Tyrosine | 1994 |
Neocortical dialysate monoamines of rats after acute, subacute, and chronic liver shunt.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Amino Acids; Ammonia; Animals; Biogenic Monoamines; Body Weight; Cerebral Cortex; Chronic Disease; Dialysis; Disease Models, Animal; Dopamine; Extracellular Space; Hepatic Encephalopathy; Hydroxyindoleacetic Acid; Male; Norepinephrine; Phenylalanine; Rats; Rats, Wistar; Serotonin; Tryptophan; Tyrosine | 1995 |
The crystal structures of the SH2 domain of p56lck complexed with two phosphonopeptides suggest a gated peptide binding site.
Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Phosphotyrosine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein-Tyrosine Kinases; Tyrosine | 1995 |
The dynamic progression of evolved character states for aromatic amino acid biosynthesis in gram-negative bacteria.
Topics: Alcaligenes; Amino Acids; Biological Evolution; Gram-Negative Bacteria; Neisseria gonorrhoeae; Nitrosomonas; Phenylalanine; Phylogeny; Pseudomonadaceae; RNA, Bacterial; RNA, Ribosomal; Tyrosine | 1994 |
Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Base Sequence; Blotting, Western; Cattle; Cell Line; Chromatography, Affinity; Cloning, Molecular; Coated Pits, Cell-Membrane; ErbB Receptors; Humans; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Binding; Recombinant Proteins; Sequence Deletion; Tumor Cells, Cultured; Tyrosine | 1995 |
Determination of the differential effects of hydrogen bonding and water release on the binding of FK506 to native and Tyr82-->Phe82 FKBP-12 proteins using free energy simulations.
Topics: Animals; Carrier Proteins; Cattle; DNA-Binding Proteins; Heat-Shock Proteins; Humans; Hydrogen Bonding; Mathematics; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Tacrolimus; Tacrolimus Binding Proteins; Thermodynamics; Tyrosine; Water | 1995 |
Growth hormone-dependent phosphorylation of tyrosine 333 and/or 338 of the growth hormone receptor.
Topics: Amino Acid Sequence; Animals; CHO Cells; Cricetinae; Enzyme Activation; Growth Hormone; Humans; Janus Kinase 2; Mutagenesis, Site-Directed; Phenylalanine; Phosphoproteins; Phosphorylation; Phosphotyrosine; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Somatotropin; Recombinant Proteins; Sequence Deletion; Transfection; Tyrosine | 1995 |
Site-directed mutagenesis of tyrosine-71 to phenylalanine in Citrobacter freundii tyrosine phenol-lyase: evidence for dual roles of tyrosine-71 as a general acid catalyst in the reaction mechanism and in cofactor binding.
Topics: Base Sequence; Catalysis; Circular Dichroism; Citrobacter freundii; Cysteine; Kinetics; Models, Chemical; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 1995 |
Circular dichroism spectroscopy of three tyrosine-to-phenylalanine substitutions of fd gene 5 protein.
Topics: Circular Dichroism; DNA-Binding Proteins; DNA, Single-Stranded; Nucleic Acids; Phenylalanine; Protein Binding; Salts; Tyrosine; Viral Proteins | 1995 |
Fungal metabolic model for human type I hereditary tyrosinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acid Sequence; Aspergillus nidulans; Chromatography, High Pressure Liquid; Dioxygenases; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Genes, Fungal; Heptanoates; Homogentisate 1,2-Dioxygenase; Humans; Hydrolases; Models, Genetic; Molecular Sequence Data; Mutation; Open Reading Frames; Oxygenases; Phenylalanine; Restriction Mapping; Sequence Homology, Amino Acid; Tyrosine | 1995 |
Changes in the ratio of branched-chain to aromatic amino acids affect the secretion of albumin in cultured rat hepatocytes.
Topics: Amino Acids, Branched-Chain; Animals; Cells, Cultured; Gene Expression; Isoleucine; Kinetics; Leucine; Liver; Male; Phenylalanine; Rats; Rats, Wistar; RNA, Messenger; Serum Albumin; Tyrosine; Valine | 1995 |
Single tyrosine substitution in the insulin-like growth factor I receptor inhibits ligand-induced receptor autophosphorylation and internalization, but not mitogenesis.
Topics: 3T3 Cells; Adenosine Triphosphate; Animals; Base Sequence; Binding Sites; Cell Division; DNA; Mice; Molecular Sequence Data; Mutagenesis; Phenylalanine; Phosphorylation; Receptor, IGF Type 1; Structure-Activity Relationship; Transfection; Tyrosine | 1995 |
The roles of Tyr70 and Tyr225 in aspartate aminotransferase assessed by analysing the effects of mutations on the multiple reactions of the substrate analogue serine o-sulphate.
Topics: Amination; Aspartate Aminotransferases; Methionine; Mutation; Phenylalanine; Serine; Structure-Activity Relationship; Tyrosine | 1995 |
Functional analysis of sequences adjacent to dapE of Corynebacterium glutamicum reveals the presence of aroP, which encodes the aromatic amino acid transporter.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acids; Bacterial Proteins; Base Sequence; Biological Transport; Carrier Proteins; Cloning, Molecular; Corynebacterium; Escherichia coli Proteins; Molecular Sequence Data; Mutagenesis, Insertional; Phenylalanine; Protein Structure, Secondary; Tryptophan; Tyrosine | 1995 |
Potent photoaffinity labelled and iodinated antagonists of bradykinin.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Bradykinin; Female; Guinea Pigs; Ileum; Iodine Radioisotopes; Molecular Sequence Data; Phenylalanine; Photochemistry; Rats; Rats, Wistar; Tyrosine | 1995 |
The role of tyrosine-158 in O6-alkylguanine-DNA alkyltransferase activity.
Topics: Alanine; Base Sequence; Binding Sites; DNA; Humans; Kinetics; Methyltransferases; Molecular Sequence Data; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Phenylalanine; Structure-Activity Relationship; Tritium; Tyrosine | 1995 |
Serum amino acid concentrations in nine athletes before and after the 1993 Colmar ultra triathlon.
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Bicycling; Body Constitution; Brain; Cystine; Extracellular Space; Fatigue; Glutamine; Humans; Intracellular Fluid; Leucine; Male; Methionine; Phenylalanine; Plasma Volume; Running; Serotonin; Swimming; Tryptophan; Tyrosine | 1995 |
Allosteric control of acetylcholinesterase catalysis by fasciculin.
Topics: Acetylcholinesterase; Alanine; Allosteric Regulation; Allosteric Site; Amino Acid Sequence; Animals; Catalysis; Cell Line; Cholinesterase Inhibitors; Elapid Venoms; Humans; Kinetics; Mathematics; Mice; Models, Theoretical; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Transfection; Tryptophan; Tyrosine | 1995 |
Tyrosine 807 of the v-Fms oncogene product controls cell morphology and association with p120RasGAP.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Transformation, Neoplastic; DNA Replication; Genes, fms; Glutathione Transferase; GTPase-Activating Proteins; Kinetics; Mice; Oncogene Protein gp140(v-fms); Oncogenes; Phenylalanine; Plasmids; Point Mutation; Protein-Tyrosine Kinases; Proteins; ras GTPase-Activating Proteins; Recombinant Fusion Proteins; Sarcoma Viruses, Feline; Thymidine; Transfection; Tyrosine | 1995 |
The mechanism of action of phenylalanine ammonia-lyase: the role of prosthetic dehydroalanine.
Topics: Alanine; Base Sequence; Borohydrides; Catalysis; Escherichia coli; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phenylalanine Ammonia-Lyase; Recombinant Proteins; Substrate Specificity; Tyrosine | 1995 |
Increase in fluorescence upon the hydrolysis of tyrosine peptides: application to proteinase assays.
Topics: gag Gene Products, Human Immunodeficiency Virus; Gene Products, gag; HIV Protease; Hydrolysis; Molecular Sequence Data; Oligopeptides; Peptide Fragments; Peptide Hydrolases; Phenylalanine; Spectrometry, Fluorescence; Time Factors; Tyrosine | 1995 |
Environments of the four tryptophans in the extracellular domain of human tissue factor: comparison of results from absorption and fluorescence difference spectra of tryptophan replacement mutants with the crystal structure of the wild-type protein.
Topics: Base Sequence; Circular Dichroism; Drug Stability; Factor VIIa; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Point Mutation; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Restriction Mapping; Spectrometry, Fluorescence; Thromboplastin; Tryptophan; Tyrosine | 1995 |
Modification of aromatic amino acids by reactive nitrogen species.
Topics: Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Mannitol; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrogen Oxides; Oxidants; Phenylalanine; Tyrosine | 1995 |
Properties of a purified estradiol-dependent calf uterus tyrosine kinase.
Topics: Actins; Amino Acid Sequence; Animals; Calcium; Calmodulin; Cattle; Electrophoresis, Polyacrylamide Gel; Estradiol; Female; Histones; Humans; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Denaturation; Protein-Tyrosine Kinases; Receptors, Estradiol; Substrate Specificity; Tyrosine; Uterus | 1993 |
Inhibition of cathepsin E by alpha 2-macroglobulin and the resulting structural changes in the inhibitor.
Topics: alpha-Macroglobulins; Amino Acid Sequence; Cathepsin E; Cathepsins; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Microscopy, Electron; Molecular Sequence Data; Phenylalanine; Tyrosine | 1993 |
Evidence by site-directed mutagenesis supports long-range electron transfer in mouse ribonucleotide reductase.
Topics: Alanine; Animals; Aspartic Acid; Base Sequence; Binding Sites; Electron Transport; Free Radicals; Hydrogen Bonding; Macromolecular Substances; Manganese; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Ribonucleotide Reductases; Structure-Activity Relationship; Tryptophan; Tyrosine | 1995 |
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells.
Topics: Animals; Base Sequence; Binding Sites; Codon; Hydrogen Bonding; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Receptors, Nicotinic; Structure-Activity Relationship; Tyrosine; Xenopus | 1995 |
Effects of substitution of tyrosine 57 with asparagine and phenylalanine on the properties of bacteriorhodopsin.
Topics: Asparagine; Bacteriorhodopsins; Cold Temperature; Darkness; Hydrogen-Ion Concentration; Hydroxylamine; Hydroxylamines; Kinetics; Light; Phenylalanine; Photochemistry; Protons; Spectrophotometry, Ultraviolet; Tyrosine | 1995 |
Role of Tyr-22 in the binding of Pf3 ssDNA binding protein to nucleic acids.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Circular Dichroism; DNA-Binding Proteins; DNA, Single-Stranded; DNA, Viral; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Plasmids; Point Mutation; Polydeoxyribonucleotides; Polyribonucleotides; Protein Conformation; Pseudomonas Phages; Recombinant Proteins; Restriction Mapping; Spectrophotometry, Ultraviolet; Substrate Specificity; Tyrosine | 1995 |
Importance of the content and localization of tyrosine residues for thyroxine formation within the N-terminal part of human thyroglobulin.
Topics: Animals; Baculoviridae; Humans; Iodine; Kinetics; Lactoperoxidase; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Recombinant Proteins; Spodoptera; Structure-Activity Relationship; Thyroglobulin; Thyroxine; Transfection; Tyrosine | 1995 |
Prephenate dehydratase of the actinomycete Amycolatopsis methanolica: purification and characterization of wild-type and deregulated mutant proteins.
Topics: Actinobacteria; Amino Acid Sequence; Bacterial Proteins; Kinetics; Molecular Sequence Data; Phenylalanine; Prephenate Dehydratase; Sequence Alignment; Sequence Homology, Amino Acid; Tyrosine | 1995 |
Phenylalanine hydroxylase activity in preterm infants: is tyrosine a conditionally essential amino acid?
Topics: Birth Weight; Energy Intake; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1995 |
Cathestatins, new cysteine protease inhibitors produced by Penicillium citrinum.
Topics: Animals; Bone Resorption; Calcium; Chick Embryo; Cysteine Proteinase Inhibitors; Epoxy Compounds; Magnetic Resonance Spectroscopy; Organ Culture Techniques; Parathyroid Hormone; Penicillium; Phenylalanine; Skull; Structure-Activity Relationship; Tyrosine | 1995 |
Low concentrations of serum tyrosine in neuroleptic-free schizophrenics with an early onset.
Topics: Adult; Age of Onset; Brain; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Male; Middle Aged; Phenylalanine; Schizophrenia; Tryptophan; Tyrosine | 1995 |
Ortho- and meta-tyrosine formation from phenylalanine in human saliva as a marker of hydroxyl radical generation during betel quid chewing.
Topics: Areca; Calcium Compounds; Carbonates; Catechin; Cations, Divalent; Chromatography, High Pressure Liquid; Copper; Dimethyl Sulfoxide; Ethanol; Free Radical Scavengers; Humans; Iron; Isomerism; Mannitol; Mastication; Oxides; Phenylalanine; Plants, Medicinal; Reactive Oxygen Species; Reference Values; Root Canal Filling Materials; Saliva; Tyrosine | 1995 |
Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients.
Topics: Adult; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Hormones; Humans; Insulin; Leg; Leucine; Male; Muscle Proteins; Phenylalanine; Proteins; Regional Blood Flow; Splanchnic Circulation; Tyrosine | 1995 |
Metabolic effect of parenteral nutrition in dogs with obstructive jaundice.
Topics: Alkaline Phosphatase; Amino Acids; Amino Acids, Branched-Chain; Ammonia; Animals; Bilirubin; Cholestasis; Cholesterol; Common Bile Duct; Dogs; Female; Ligation; Male; Parenteral Nutrition, Total; Phenylalanine; Triglycerides; Tyrosine | 1995 |
Evidence for residual structures in an unfolded form of yeast phosphoglycerate kinase.
Topics: Guanidine; Guanidines; Mutagenesis, Site-Directed; Phenylalanine; Phosphoglycerate Kinase; Protein Conformation; Protein Folding; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Urea | 1995 |
Genetic aspects of aromatic amino acid biosynthesis in Lactococcus lactis.
Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Amino Acids; Bacterial Proteins; Base Sequence; Chorismate Mutase; Conserved Sequence; Escherichia coli Proteins; Folic Acid; Genes, Bacterial; Genetic Complementation Test; Lactococcus lactis; Molecular Sequence Data; Multienzyme Complexes; Operon; Phenylalanine; Phosphotransferases (Alcohol Group Acceptor); Prephenate Dehydratase; Promoter Regions, Genetic; Protein Sorting Signals; Sequence Alignment; Sequence Analysis, DNA; Shikimic Acid; Transferases; Tryptophan; Tyrosine | 1995 |
Effect of a mutation at tyrosine 950 of the insulin-like growth factor I receptor on the growth and transformation of cells.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cell Transformation, Neoplastic; Clone Cells; DNA; DNA Primers; Humans; Insulin-Like Growth Factor I; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Receptor, IGF Type 1; Recombinant Proteins; Transfection; Tyrosine | 1995 |
A single amino acid substitution in somatostatin receptor subtype 5 increases affinity for somatostatin-14.
Topics: Amino Acid Sequence; Animals; Base Sequence; CHO Cells; Cricetinae; DNA, Complementary; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Rats; Receptors, Somatostatin; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Somatostatin; Structure-Activity Relationship; Tyrosine | 1995 |
NMR behavior of the aromatic protons of bovine neurophysin-I and its peptide complexes: implications for solution structure and for function.
Topics: Animals; Cattle; Dipeptides; Ligands; Magnetic Resonance Spectroscopy; Molecular Structure; Neurophysins; Oxytocin; Phenylalanine; Solutions; Tyrosine | 1995 |
Simultaneous monitoring of the environment of tryptophan, tyrosine, and phenylalanine residues in proteins by near-ultraviolet second-derivative spectroscopy.
Topics: Phenylalanine; Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1994 |
Phenylalanine and tyrosine kinetics in young men throughout a continuous 24-h period, at a low phenylalanine intake.
Topics: Administration, Oral; Adult; Breath Tests; Calorimetry, Indirect; Energy Intake; Fasting; Humans; Hydroxylation; Infusions, Intravenous; Kinetics; Male; Oxidation-Reduction; Phenylalanine; Tyrosine | 1995 |
Mutations in two specific residues of testicular angiotensin-converting enzyme change its catalytic properties.
Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding Sites; Binding, Competitive; Gene Expression; Genetic Vectors; Glutamates; Glutamic Acid; HeLa Cells; Humans; Kinetics; Lisinopril; Lysine; Male; Mutagenesis; Peptidyl-Dipeptidase A; Phenylalanine; Point Mutation; Rabbits; Recombinant Proteins; Substrate Specificity; Testis; Transfection; Tyrosine; Vaccinia virus | 1993 |
[Genetic control of the synthesis of enzymes of the common site for the aromatic pathway in Pseudomonas bacteria].
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Genes, Bacterial; Mutation; Phenylalanine; Pseudomonas; Repressor Proteins; Tyrosine | 1994 |
Synergistic action of near-UV and phenylalanine, tyrosine or tryptophan on the inactivation of phage T7: role of superoxide radicals and hydrogen peroxide.
Topics: Bacteriophage T7; DNA Damage; DNA, Viral; Dose-Response Relationship, Radiation; Escherichia coli; Free Radical Scavengers; Humans; Hydrogen Peroxide; Neoplasms, Radiation-Induced; Phenylalanine; Photosensitizing Agents; Skin Neoplasms; Sunlight; Superoxides; Tryptophan; Tyrosine; Ultraviolet Rays | 1994 |
Does the edge-to-face interaction between aromatic rings occur in cyclolinopeptide A analogues?
Topics: Amino Acid Sequence; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Peptides, Cyclic; Phenylalanine; Spectrometry, Fluorescence; Spectrum Analysis; Tyrosine | 1994 |
Severity of mutation in the phenylalanine hydroxylase gene influences phenylalanine metabolism in phenylketonuria and hyperphenylalaninaemia heterozygotes.
Topics: Adult; DNA; Female; Genotype; Heterozygote; Humans; Male; Mutation; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Regression Analysis; Tyrosine | 1994 |
An assessment of progression of brain edema with amino acid levels in cerebrospinal fluid and changes in electroencephalogram in an adult cat model of cold brain injury.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Blood-Brain Barrier; Brain Edema; Brain Injuries; Cats; Electroencephalography; Evoked Potentials; Freezing; Glutamic Acid; Methionine; Motor Cortex; Phenylalanine; Serine; Synaptic Transmission; Tyrosine; Valine | 1994 |
Aromatic amino acid metabolism of neonatal piglets receiving TPN: effect of tyrosine precursors.
Topics: Amino Acids; Animals; Animals, Newborn; Body Composition; Dipeptides; Male; Nitrogen; Parenteral Nutrition, Total; Phenylalanine; Swine; Tyrosine | 1994 |
The role of tryptophan 97 of cytochrome P450 BM3 from Bacillus megaterium in catalytic function. Evidence against the 'covalent switching' hypothesis of P-450 electron transfer.
Topics: Alanine; Bacillus megaterium; Bacterial Proteins; Base Sequence; Catalysis; Circular Dichroism; Cytochrome P-450 Enzyme System; DNA Primers; Electron Spin Resonance Spectroscopy; Electron Transport; Escherichia coli; Heme; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; NADPH-Ferrihemoprotein Reductase; Phenylalanine; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1994 |
Preloading with L-tyrosine increases the uptake of boronophenylalanine in mouse melanoma cells.
Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Melanoma; Mice; Phenylalanine; Radiation-Sensitizing Agents; Time Factors; Tumor Cells, Cultured; Tyrosine | 1994 |
Residues specific for class III alcohol dehydrogenase. Site-directed mutagenesis of the human enzyme.
Topics: Alcohol Dehydrogenase; Asparagine; Base Sequence; Binding Sites; Fomepizole; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Pyrazoles; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 1994 |
Fluorogenic peptides containing only alpha-amino acids.
Topics: Amino Acid Sequence; Angiotensinogen; Animals; Endopeptidases; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Oligopeptides; Phenylalanine; Renin; Spectrometry, Fluorescence; Substrate Specificity; Swine; Tryptophan; Tyrosine | 1994 |
Phenylalanine and tyrosine kinetics for different patterns and indispensable amino acid intakes in adult humans.
Topics: Adult; Amino Acids; Diet; Egg Proteins, Dietary; Fasting; Homeostasis; Humans; Hydroxylation; Infusions, Intravenous; Male; Nutritional Requirements; Phenylalanine; Tyrosine | 1994 |
Effects of tyrosine-->phenylalanine mutations on auto- and trans-phosphorylation reactions catalyzed by the insulin receptor beta-subunit cytoplasmic domain.
Topics: Animals; Catalysis; Cell Line; Cytoplasm; Enzyme Activation; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Receptor, Insulin; Tyrosine | 1994 |
Evidence for the importance of hydrophobic residues in the interactions between the cAMP-dependent protein kinase catalytic subunit and the protein kinase inhibitors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Catalysis; Codon; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA; Humans; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphotransferases; Tyrosine; Water | 1994 |
Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; CHO Cells; Cricetinae; ErbB Receptors; Glutathione Transferase; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligopeptides; Phenylalanine; Phosphorylation; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transfection; Tyrosine | 1994 |
Four aromatic residues in the active center of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. 1011: effects of replacements on substrate binding and cyclization characteristics.
Topics: Acarbose; Amino Acid Sequence; Bacillus; Base Sequence; Binding Sites; Crystallization; Crystallography, X-Ray; Cyclization; Enzyme Stability; Glucosyltransferases; Glycosylation; Hydrogen-Ion Concentration; Hydrolysis; Molecular Sequence Data; Molecular Structure; Mutagenesis, Site-Directed; Phenylalanine; Starch; Structure-Activity Relationship; Trisaccharides; Tyrosine | 1994 |
Amino acid profile and aromatic amino acid concentration in total parenteral nutrition: effect on growth, protein metabolism and aromatic amino acid metabolism in the neonatal piglet.
Topics: Amino Acids; Animals; Animals, Newborn; Food, Formulated; Lysine; Nitrogen; Parenteral Nutrition, Total; Phenylalanine; Swine; Tyrosine | 1994 |
Phenylalanine and tyrosine kinetics in critically ill children with sepsis.
Topics: Bacterial Infections; Critical Illness; Humans; Hydroxylation; Infant; Infant, Newborn; Infusions, Intravenous; Kinetics; Nutritional Requirements; Phenylalanine; Tyrosine | 1994 |
Further studies on the adjuvanticity of stearyl tyrosine and amide analogues.
Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Female; Mice; Mice, Inbred BALB C; Phenylalanine; Stearates; Tyrosine | 1994 |
The effect of elevated plasma phenylalanine levels on protein synthesis rates in adult rat brain.
Topics: Animals; Brain; Chromatography, Ion Exchange; Kinetics; Male; Phenylalanine; Protein Biosynthesis; Protein Precursors; Rats; Rats, Sprague-Dawley; RNA, Transfer, Amino Acyl; Tyrosine; Valine | 1994 |
Studies on neurochemical heterogeneity in healthy parents of schizophrenic patients.
Topics: Adult; Aged; Antipsychotic Agents; Female; Homovanillic Acid; Humans; Male; Middle Aged; Norepinephrine; Phenotype; Phenylalanine; Prognosis; Risk Factors; Schizophrenia; Schizophrenic Psychology; Sex Factors; Tyrosine | 1993 |
Failure of dietary amino acid supplementation at weaning to influence reproductive traits of sows.
Topics: Amino Acids; Animal Feed; Animals; Estrus; Female; Fetal Death; Food, Fortified; Glutamates; Glutamic Acid; Litter Size; Ovulation; Parity; Phenylalanine; Pregnancy; Reproduction; Swine; Tyrosine; Weaning | 1993 |
Purification of the Escherichia coli regulatory protein TyrR and analysis of its interactions with ATP, tyrosine, phenylalanine, and tryptophan.
Topics: Adenosine Triphosphate; Base Sequence; Cell-Free System; Chromatography, Gel; Chromatography, Ion Exchange; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Genes, Regulator; Kinetics; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Phenylalanine; Plasmids; Repressor Proteins; Restriction Mapping; Transcription Factors; Tryptophan; Tyrosine | 1994 |
Phenylalanine and other amino acids in phenylketonuria.
Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Tyrosine | 1993 |
Shift in pH-rate profile and enhanced discrimination between dicarboxylic and aromatic substrates in mitochondrial aspartate aminotransferase Y70H.
Topics: Amino Acid Sequence; Animals; Aspartate Aminotransferases; Aspartic Acid; Chickens; Circular Dichroism; Hydrogen-Ion Concentration; Kinetics; Mitochondria; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Recombinant Proteins; Spectrophotometry; Substrate Specificity; Tryptophan; Tyrosine | 1994 |
Lactate monooxygenase. III. Additive contributions of active site residues to catalytic efficiency and stabilization of an anionic transition state.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Kinetics; Mixed Function Oxygenases; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oxalates; Phenylalanine; Recombinant Proteins; Tyrosine | 1994 |
Capillary zone electrophoresis determination of phenylalanine in serum: a rapid, inexpensive and simple method for the diagnosis of phenylketonuria.
Topics: Capillary Action; Electrophoresis; Humans; Phenylalanine; Phenylketonurias; Quality Control; Tryptophan; Tyrosine | 1994 |
Oncogenic activation of p59fyn tyrosine protein kinase by mutation of its carboxyl-terminal site of tyrosine phosphorylation, tyrosine 528.
Topics: 3T3 Cells; Animals; Catalysis; Cell Transformation, Neoplastic; Enzyme Activation; Mice; Mutation; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Tyrosine | 1994 |
Substitution of tyrosine 293 of GLUT1 locks the transporter into an outward facing conformation.
Topics: Affinity Labels; Amino Acid Sequence; Animals; Azides; Base Sequence; Blotting, Western; Cell Membrane; CHO Cells; Cricetinae; Cytochalasin B; Deoxyglucose; Disaccharides; DNA Primers; Electrophoresis, Polyacrylamide Gel; Glucose Transporter Type 1; Glycosides; Humans; Isoleucine; Kinetics; Molecular Sequence Data; Molecular Weight; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Propylamines; Protein Conformation; Recombinant Proteins; Transfection; Tyrosine | 1994 |
Ligand-induced self-association of the Escherichia coli regulatory protein TyrR.
Topics: Adenosine Triphosphate; Base Sequence; Centrifugation, Density Gradient; DNA-Binding Proteins; Escherichia coli; Escherichia coli Proteins; Ligands; Molecular Sequence Data; Molecular Weight; Operator Regions, Genetic; Phenylalanine; Polymers; Regulatory Sequences, Nucleic Acid; Repressor Proteins; Transcription Factors; Tyrosine | 1994 |
Insulin selectively attenuates breakdown of nonmyofibrillar proteins in peripheral tissues of normal men.
Topics: Adult; Arm; Arteries; Humans; Insulin; Kinetics; Leg; Male; Methylhistidines; Middle Aged; Muscle Proteins; Muscles; Phenylalanine; Tyrosine | 1994 |
Phenylalanine- and tyrosine-dependent production of enterobactin in Escherichia coli.
Topics: Catechols; Enterobactin; Escherichia coli; Genes, Bacterial; Iron; Mutation; Phenylalanine; Tyrosine | 1994 |
Blue shifts in bacteriochlorophyll absorbance correlate with changed hydrogen bonding patterns in light-harvesting 2 mutants of Rhodobacter sphaeroides with alterations at alpha-Tyr-44 and alpha-Tyr-45.
Topics: Bacteriochlorophylls; Fourier Analysis; Hydrogen Bonding; Leucine; Light-Harvesting Protein Complexes; Mutagenesis, Site-Directed; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Protein Conformation; Rhodobacter sphaeroides; Spectrum Analysis, Raman; Tyrosine | 1994 |
Amino/aromatic interactions in proteins: is the evidence stacked against hydrogen bonding?
Topics: Amino Acid Sequence; Amino Acids; Arginine; Asparagine; Benzene; Calorimetry; Guanidine; Guanidines; Histidine; Hydrogen Bonding; Mathematics; Models, Molecular; Phenylalanine; Protein Conformation; Proteins; Tryptophan; Tyrosine | 1994 |
Source and amount of dietary nonspecific nitrogen in relation to whole-body leucine, phenylalanine, and tyrosine kinetics in young men.
Topics: Adult; Amino Acids; Carbon Dioxide; Diet; Humans; Leucine; Male; Models, Biological; Nitrogen; Phenylalanine; Respiration; Tyrosine | 1994 |
Inhibition of binding of phospholipase C gamma 1 SH2 domains to phosphorylated epidermal growth factor receptor by phosphorylated peptides.
Topics: Amino Acid Sequence; Binding Sites; ErbB Receptors; Molecular Sequence Data; Peptides; Phenylalanine; Phosphorylation; Protein Binding; Signal Transduction; Type C Phospholipases; Tyrosine | 1993 |
Probing weakly polar interactions in cytochrome c.
Topics: Cysteine; Cytochrome c Group; Cytochromes c; Guanidine; Guanidines; Magnetic Resonance Spectroscopy; Methionine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Denaturation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thermodynamics; Tyrosine | 1993 |
Experimental research on a fetal treatment for tetrahydrobiopterin deficiency.
Topics: Adrenal Glands; Animals; Biopterins; Corpus Striatum; Dopamine; Epinephrine; Female; Fetal Blood; Guinea Pigs; Hypoxanthines; Infusions, Intravenous; Liver; Maternal-Fetal Exchange; Metabolism, Inborn Errors; Norepinephrine; Phenylalanine; Phenylketonurias; Pregnancy; Tyrosine | 1993 |
Experimental research on a new treatment for maternal phenylketonuria(PKU).
Topics: Animals; Biopterins; Brain; Disease Models, Animal; Female; Fetus; Guinea Pigs; Infusions, Intravenous; Liver; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1993 |
Nitrogen homeostasis in man: the diurnal responses of protein synthesis and degradation and amino acid oxidation to diets with increasing protein intakes.
Topics: Adult; Amino Acids; Circadian Rhythm; Dietary Proteins; Fasting; Female; Glycine; Homeostasis; Humans; Leucine; Male; Middle Aged; Nitrogen; Oxidation-Reduction; Phenylalanine; Proteins; Tyrosine | 1994 |
Mutation of tyrosine-67 to phenylalanine in cytochrome c significantly alters the local heme environment.
Topics: Cytochrome c Group; Electron Transport; Escherichia coli; Heme; Hydrogen Bonding; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptides; Phenylalanine; Protein Conformation; Saccharomyces cerevisiae; Tyrosine | 1994 |
Crystal structures of mutant Pseudomonas aeruginosa p-hydroxybenzoate hydroxylases: the Tyr201Phe, Tyr385Phe, and Asn300Asp variants.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Asparagine; Aspartic Acid; Crystallization; Crystallography, X-Ray; Electrochemistry; Hydrogen Bonding; Hydrogen-Ion Concentration; Molecular Structure; Mutation; Parabens; Phenylalanine; Pseudomonas aeruginosa; Tyrosine | 1994 |
Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite.
Topics: Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Serum Albumin, Bovine; Thermodynamics; Tyrosine; Uric Acid | 1994 |
Effect of the immediate precursors of phenylalanine and tyrosine on growth and protein synthesis in phenylalanine- and tyrosine-deprived HeLa cells.
Topics: Cell Division; HeLa Cells; Humans; Phenylalanine; Phenylpyruvic Acids; Protein Biosynthesis; Tyrosine | 1993 |
Tyr26 and Phe73 are essential for full biological activity of the Fd gene 5 protein.
Topics: Amino Acid Sequence; Bacteriophages; Base Sequence; DNA-Binding Proteins; DNA, Viral; Escherichia coli; Molecular Sequence Data; Mutagenesis; Phenylalanine; Tyrosine; Viral Proteins | 1993 |
Local variations in protein structure in the human eye lens: a Raman microspectroscopic study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Crystallins; Eye Proteins; Humans; Lens, Crystalline; Microchemistry; Middle Aged; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 1993 |
Organ clearance of tyrosyl-arginine and its effect on amino acid metabolism in young sheep.
Topics: Aging; Amino Acids; Analgesics; Animals; Arginine; Citrulline; Endorphins; Female; Hindlimb; Intestinal Mucosa; Intestines; Isoleucine; Kidney; Leucine; Liver; Metabolic Clearance Rate; Organ Specificity; Phenylalanine; Regional Blood Flow; Sheep; Tyrosine; Valine | 1993 |
Structure of the complex between pyridoxal 5'-phosphate and the tyrosine 225 to phenylalanine mutant of Escherichia coli aspartate aminotransferase determined by isotope-edited classical Raman difference spectroscopy.
Topics: Aspartate Aminotransferases; Chemical Phenomena; Chemistry, Physical; Escherichia coli; Hydrogen Bonding; Molecular Structure; Mutation; Phenylalanine; Pyridoxal Phosphate; Schiff Bases; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tyrosine | 1993 |
Role of Tyr201 and Tyr385 in substrate activation by p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Base Sequence; Benzoates; Binding Sites; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutation; Parabens; Phenylalanine; Pseudomonas fluorescens; Tyrosine | 1993 |
Development of active center-directed plasmin and plasma kallikrein inhibitors and studies on the structure-inhibitory activity relationship.
Topics: Amino Acid Sequence; Amino Acids; Animals; Fibrinolysin; Humans; Kallikreins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phenylalanine; Structure-Activity Relationship; Tranexamic Acid; Tyrosine | 1993 |
The alpha-type 85-kDa subunit of phosphatidylinositol 3-kinase is phosphorylated at tyrosines 368, 580, and 607 by the insulin receptor.
Topics: Amino Acid Sequence; Animals; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Glutathione Transferase; HeLa Cells; Humans; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases; Receptor, Insulin; Recombinant Fusion Proteins; Tyrosine | 1993 |
Reduction of cytochrome C by fragments of heat shock protein 70.
Topics: Amino Acid Sequence; Cysteine; Cytochrome c Group; Heat-Shock Proteins; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Spectrophotometry; Tyrosine | 1993 |
Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning.
Topics: Animals; Antioxidants; Coronary Circulation; Dogs; Female; Hydroxides; Hydroxyl Radical; Hydroxylation; Male; Myocardial Infarction; Myocardium; Phenylalanine; Tyrosine | 1993 |
Formation of a hydroxyl radical by the myeloperoxidase-NADH-oxygen system.
Topics: Aerobiosis; Catalase; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Kinetics; NAD; Oxygen; Peroxidase; Phenylalanine; Superoxide Dismutase; Tyrosine | 1993 |
Changes in global stability and local structure of cytochrome c upon substituting phenylalanine-82 with tyrosine.
Topics: Cytochrome c Group; Enzyme Stability; Molecular Structure; Phenylalanine; Saccharomyces cerevisiae; Tyrosine | 1993 |
Improved identification of heterozygotes for phenylketonuria using blood neopterin and biopterin.
Topics: Adult; Biopterins; Female; Genetic Carrier Screening; Humans; Male; Neopterin; Phenylalanine; Phenylketonurias; Tyrosine | 1993 |
Phenylalanine conversion to tyrosine: comparative determination with L-[ring-2H5]phenylalanine and L-[1-13C]phenylalanine as tracers in man.
Topics: Adult; Carbon Isotopes; Humans; Hydroxylation; Male; Oxidation-Reduction; Phenylalanine; Time Factors; Tyrosine | 1993 |
Plasma phenylalanine and tyrosine responses to different nutritional conditions (fasting/postprandial) in patients with phenylketonuria: effect of sample timing.
Topics: Blood Specimen Collection; Child; Child, Preschool; Fasting; Food; Humans; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1993 |
Mutational uncoupling of the transcriptional activation function of the TyrR protein of Escherichia coli K-12 from the repression function.
Topics: DNA Mutational Analysis; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Phenylalanine; Promoter Regions, Genetic; Repressor Proteins; Structure-Activity Relationship; Transcription Factors; Transcription, Genetic; Tyrosine | 1993 |
Rapid diagnosis of phenylketonuria by quantitative analysis for phenylalanine and tyrosine in neonatal blood spots by tandem mass spectrometry.
Topics: Humans; Infant, Newborn; Mass Spectrometry; Neonatal Screening; North Carolina; Phenylalanine; Phenylketonurias; Quality Control; Reference Values; Tyrosine | 1993 |
Relationship among cyanide-induced encephalopathy, blood ammonia levels, and brain aromatic amino acid levels in rats.
Topics: Acetates; Alanine; Ammonia; Animals; Brain Chemistry; Coma; Drug Combinations; Male; Mice; Phenylalanine; Potassium Cyanide; Rats; Rats, Wistar; Tyrosine | 1993 |
Aromatic-histidine interactions in the zinc finger motif: structural inequivalence of phenylalanine and tyrosine in the hydrophobic core.
Topics: Amino Acid Sequence; Circular Dichroism; Histidine; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Protein Conformation; Tyrosine; Zinc Fingers | 1993 |
Modification of the amino acid specificity of tyrosyl-tRNA synthetase by protein engineering.
Topics: Adenosine Triphosphate; Bacterial Proteins; Base Sequence; Binding Sites; Geobacillus stearothermophilus; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Protein Biosynthesis; Protein Engineering; Recombinant Proteins; RNA, Transfer, Tyr; Structure-Activity Relationship; Transfer RNA Aminoacylation; Tyrosine; Tyrosine-tRNA Ligase | 1993 |
Static and time-resolved absorption spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: evidence for an equilibrium between bR570 and an O-like species.
Topics: Bacteriorhodopsins; Darkness; Halobacterium salinarum; Hydrogen-Ion Concentration; Light; Mutation; Osmolar Concentration; Phenylalanine; Spectrophotometry, Ultraviolet; Tyrosine | 1993 |
Fourier transform Raman spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: formation of a stable O-like species during light adaptation and detection of its transient N-like photoproduct.
Topics: Bacteriorhodopsins; Darkness; Fourier Analysis; Halobacterium salinarum; Light; Mutation; Phenylalanine; Photochemistry; Spectrum Analysis, Raman; Tyrosine | 1993 |
FTIR difference spectroscopy of the bacteriorhodopsin mutant Tyr-185-->Phe: detection of a stable O-like species and characterization of its photocycle at low temperature.
Topics: Bacteriorhodopsins; Cold Temperature; Fourier Analysis; Halobacterium salinarum; Mutation; Phenylalanine; Photochemistry; Spectrophotometry, Infrared; Tyrosine | 1993 |
Unassigned or nonsense codons in Micrococcus luteus.
Topics: Adenine Nucleotides; Amino Acid Sequence; Anticodon; Arginine; Base Composition; Base Sequence; Codon; DNA, Bacterial; Genetic Code; Genetics, Microbial; Isoleucine; Micrococcus luteus; Molecular Sequence Data; Phenylalanine; Protein Biosynthesis; RNA, Transfer; Tyrosine | 1993 |
The mechanism of action of DD-peptidases: the role of tyrosine-159 in the Streptomyces R61 DD-peptidase.
Topics: Anti-Bacterial Agents; Base Sequence; Chemical Phenomena; Chemistry, Physical; Enzyme Stability; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Lactams; Molecular Sequence Data; Muramoylpentapeptide Carboxypeptidase; Mutagenesis; Phenylalanine; Plasmids; Recombinant Proteins; Serine; Streptomyces; Structure-Activity Relationship; Tyrosine | 1993 |
Role of tyrosine-5 in the cytoplasmic tail of the macrophage asialoglycoprotein receptor in the rapid internalization of ligands.
Topics: Amino Acid Sequence; Animals; Asialoglycoproteins; Base Sequence; Carrier Proteins; Cell Line; Cytoplasm; DNA; Lectins; Macrophages; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Receptors, Cell Surface; Transfection; Tyrosine | 1993 |
Plasma phenylalanine and tyrosine levels revisited in heterozygotes for hyperphenylalaninaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Bayes Theorem; Female; Heterozygote; Humans; Male; Phenylalanine; Risk Factors; Tyrosine | 1993 |
Sequence-specific cleavage of DNA via nucleophilic attack of hydrogen peroxide, assisted by Flp recombinase.
Topics: Base Sequence; DNA Nucleotidyltransferases; DNA, Bacterial; Drug Synergism; Hydrogen Peroxide; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1993 |
Site-directed alteration of three active-site residues of a pyruvoyl-dependent histidine decarboxylase.
Topics: Alanine; Allosteric Regulation; Asparagine; Binding Sites; Histidine; Histidine Decarboxylase; Hydrogen-Ion Concentration; Isoleucine; Kinetics; Lactobacillus; Mutagenesis, Site-Directed; Phenylalanine; Pyruvates; Pyruvic Acid; Recombinant Proteins; Tyrosine; Valine | 1993 |
Mutational analysis of conserved tyrosines in the NS-1 protein of the parvovirus minute virus of mice.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cells, Cultured; DNA Mutational Analysis; DNA Replication; Minute Virus of Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transcriptional Activation; Transfection; Tyrosine; Viral Nonstructural Proteins | 1993 |
Mutation of a phenylalanine conserved in SH3-containing tyrosine kinases activates the transforming ability of c-Abl.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Transformation, Neoplastic; Conserved Sequence; Gene Expression Regulation; Genes, abl; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Phenylalanine; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; Structure-Activity Relationship; Tyrosine | 1993 |
Decreased plasma proteins, increased total plasma-free amino acids, and disturbed amino acid metabolism in the hereditary severe anemia of the Belgrade laboratory (b/b) rat.
Topics: Alanine; Amino Acids; Anemia, Hypochromic; Animals; Blood Proteins; Blood Transfusion; Female; Glutamine; Heterozygote; Homozygote; Male; Methylhistidines; Phenylalanine; Rats; Rats, Mutant Strains; Tyrosine; Urea | 1993 |
Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Cell Division; Cell Line; Colony-Stimulating Factors; DNA-Binding Proteins; Erythropoietin; Janus Kinase 2; Milk Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; ras Proteins; Receptors, Erythropoietin; Shc Signaling Adaptor Proteins; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1995 |
Chorismate mutase and 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of the methylotrophic actinomycete Amycolatopsis methanolica.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Actinobacteria; Amino Acid Sequence; Chorismate Mutase; Enzyme Activation; Kinetics; Molecular Sequence Data; Mutation; Phenylalanine; Protein Conformation; Tyrosine | 1995 |
Motif of HLA-B*3503 peptide ligands.
Topics: Amino Acid Sequence; DNA, Complementary; HLA-B Antigens; Ligands; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Recombinant Proteins; Structure-Activity Relationship; Tyrosine | 1996 |
Mid-second trimester organic acids in severe open neural tube defects.
Topics: Amniocentesis; Amniotic Fluid; Anencephaly; Female; Humans; Hydrolases; Phenylalanine; Pregnancy; Pregnancy Trimester, Second; Spinal Dysraphism; Tyrosine | 1995 |
Intravenous gamma-glutamyl-tyrosine elevates brain tyrosine but not catecholamine concentrations in normal rats.
Topics: Animals; Brain; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid; Dipeptides; Dopamine; Homovanillic Acid; Infusions, Intravenous; Male; Norepinephrine; Parenteral Nutrition, Total; Phenylalanine; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine | 1996 |
Effect of tyrosine mutations on the kinase activity and transforming potential of an oncogenic human insulin-like growth factor I receptor.
Topics: Animals; Cell Transformation, Neoplastic; Chick Embryo; Humans; Insulin Receptor Substrate Proteins; Isoenzymes; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein-Tyrosine Kinases; Receptor, IGF Type 1; Signal Transduction; Type C Phospholipases; Tyrosine | 1996 |
Monamidocin, a novel fibrinogen receptor antagonist. II. Biological activity and structure-activity relationships.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Collagen; Fibrinogen; Humans; Molecular Sequence Data; Molecular Structure; Phenylalanine; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Streptomyces; Structure-Activity Relationship; Thrombin; Tyrosine | 1995 |
Analysis of an Escherichia coli mutant TyrR protein with impaired capacity for tyrosine-mediated repression, but still able to activate at sigma 70 promoters.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Base Sequence; Binding Sites; DNA Primers; DNA-Directed RNA Polymerases; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Promoter Regions, Genetic; Protein Conformation; Repressor Proteins; Sigma Factor; Tryptophan; Tyrosine | 1995 |
Evidence for two aromatic amino acid-binding sites, one ATP-dependent and the other ATP-independent, in the Escherichia coli regulatory protein TyrR.
Topics: Adenosine Triphosphate; Amino Acids; Binding Sites; Binding, Competitive; Escherichia coli; Escherichia coli Proteins; Kinetics; Phenylalanine; Protein Conformation; Repressor Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1995 |
Parenteral glycyl-L-tyrosine maintains tyrosine pools and supports growth and nitrogen balance in phenylalanine-deficient rats.
Topics: Amino Acids; Analysis of Variance; Animals; Body Weight; Chromatography, High Pressure Liquid; Dipeptides; Growth; Kidney; Liver; Male; Muscles; Nitrogen; Parenteral Nutrition; Phenylalanine; Random Allocation; Rats; Rats, Wistar; Tyrosine | 1996 |
Benign tyrosinaemia: an 18-year follow-up.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Child; Diet; Dietary Proteins; Follow-Up Studies; Hemiplegia; Humans; Male; Phenylalanine; Tyrosine | 1995 |
Twenty-four-hour intravenous and oral tracer studies with L-[1-13C]phenylalanine and L-[3,3-2H2]tyrosine at a tyrosine-free, generous phenylalanine intake in adults.
Topics: Administration, Oral; Adult; Carbon Dioxide; Carbon Isotopes; Circadian Rhythm; Deuterium; Humans; Hydroxylation; Injections, Intravenous; Leucine; Male; Oxidation-Reduction; Phenylalanine; Tyrosine | 1996 |
Phorbol 12-myristate 13-acetate enhances nm23 gene expression in murine melanocytes but not in syngeneic B16-BL6 melanoma variants.
Topics: Animals; Cell Division; Cell Membrane; Cytosol; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Melanocytes; Melanoma, Experimental; Mice; Monomeric GTP-Binding Proteins; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phenylalanine; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Tyrosine | 1996 |
Hyperglucagonemia stimulates phenylalanine oxidation in humans.
Topics: Adult; Carbon Radioisotopes; Glucagon; Growth Hormone; Humans; Infusions, Intravenous; Insulin; Kinetics; Leucine; Liver; Male; Oxidation-Reduction; Phenylalanine; Radioisotope Dilution Technique; Reference Values; Somatostatin; Time Factors; Tyrosine | 1996 |
Attachment, invasion, chemotaxis, and proteinase expression of B16-BL6 melanoma cells exhibiting a low metastatic phenotype after exposure to dietary restriction of tyrosine and phenylalanine.
Topics: Animals; Cell Adhesion; Chemotaxis; Diet; Melanoma, Experimental; Metalloendopeptidases; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Phenylalanine; Plasminogen Activators; Receptors, Fibronectin; Tyrosine | 1996 |
Proteolysis and phenylalanine hydroxylation in response to parenteral nutrition in extremely premature and normal newborns.
Topics: Amino Acids; Blood Glucose; Female; Humans; Hydroxylation; Infant, Newborn; Infant, Premature; Insulin; Kinetics; Male; Parenteral Nutrition; Phenylalanine; Proteins; Tyrosine | 1996 |
Structural determinants in the platelet-derived growth factor alpha-receptor implicated in modulation of chemotaxis.
Topics: Amino Acid Sequence; Animals; Aorta; Base Sequence; Becaplermin; Cell Line; Chemotaxis; Endothelium, Vascular; Enzyme Activation; Humans; Inositol Phosphates; Isoenzymes; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Peptide Fragments; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphopeptides; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Point Mutation; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor alpha; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Swine; Transfection; Type C Phospholipases; Tyrosine | 1996 |
Mutation of Tyr235 in the NAD(H)-binding subunit of the proton-translocating nicotinamide nucleotide transhydrogenase of Rhodospirillum rubrum affects the conformational dynamics of a mobile loop and lowers the catalytic activity of the enzyme.
Topics: Asparagine; Binding Sites; Biological Transport; Catalysis; Magnetic Resonance Spectroscopy; NAD; NADP Transhydrogenases; Phenylalanine; Protein Conformation; Rhodospirillum rubrum; Spectrometry, Fluorescence; Structure-Activity Relationship; Tryptophan; Tyrosine | 1996 |
Role of aromatic transmembrane residues of the delta-opioid receptor in ligand recognition.
Topics: Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Ligands; Membrane Proteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Narcotics; Phenylalanine; Protein Structure, Tertiary; Receptors, Opioid, delta; Recombinant Proteins; Structure-Activity Relationship; Tryptophan; Tyrosine | 1996 |
Comparison of the effects of ozone on the modification of amino acid residues in glutamine synthetase and bovine serum albumin.
Topics: Amino Acid Sequence; Amino Acids; Animals; Cattle; Escherichia coli; Glutamate-Ammonia Ligase; Histidine; Kinetics; Methionine; Molecular Sequence Data; Oligopeptides; Oxidation-Reduction; Ozone; Phenylalanine; Serum Albumin, Bovine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1996 |
The full oncogenic activity of Ret/ptc2 depends on tyrosine 539, a docking site for phospholipase Cgamma.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Drosophila Proteins; Glutathione Transferase; HeLa Cells; Humans; Isoenzymes; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oncogene Proteins; Phenylalanine; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Proto-Oncogenes; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Transfection; Type C Phospholipases; Tyrosine | 1996 |
Ligand effects on the fluorescence properties of tyrosine-9 in alpha 1-1 glutathione S-transferase.
Topics: Animals; Binding Sites; Glutathione; Glutathione Transferase; Hydrogen Bonding; Isoenzymes; Kinetics; Ligands; Mammals; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Rats; Recombinant Proteins; Spectrometry, Fluorescence; Tyrosine | 1996 |
Potent inhibitors of cysteine proteases from the marine fungus Microascus longirostris.
Topics: Ascomycota; Carboxypeptidases; Cathepsin A; Cathepsin B; Cysteine Proteinase Inhibitors; Epoxy Compounds; Fermentation; Magnetic Resonance Spectroscopy; Molecular Structure; Papain; Phenylalanine; Tyrosine | 1996 |
[Recombinant human hemoglobin with low oxygen affinity: additional effects of two mutations].
Topics: Allosteric Regulation; Aspartic Acid; Hemoglobins; Humans; Kinetics; Lysine; Mutation; Oxidation-Reduction; Oxygen; Phenylalanine; Recombinant Proteins; Tyrosine | 1995 |
Evidence for a physical association between the Shc-PTB domain and the beta c chain of the granulocyte-macrophage colony-stimulating factor receptor.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Cell Line; GRB2 Adaptor Protein; Janus Kinase 2; Molecular Sequence Data; Phenylalanine; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Signal Transduction; src Homology Domains; Tyrosine | 1996 |
Identification of a critical ligand binding determinant of the human erythropoietin receptor. Evidence for common ligand binding motifs in the cytokine receptor family.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cell Membrane; Chlorocebus aethiops; Cloning, Molecular; Conserved Sequence; Erythropoietin; Escherichia coli; Humans; Kinetics; Ligands; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Structure, Secondary; Receptors, Cytokine; Receptors, Erythropoietin; Recombinant Proteins; Sequence Homology, Amino Acid; Transfection; Tryptophan; Tyrosine | 1996 |
Neurotransmitter and monoaminergic amino acid precursor levels in rat brain: effects of chronic renal failure and of malnutrition.
Topics: Amino Acids; Animals; Brain; Dopamine; Female; Histamine; Histidine; Kidney Failure, Chronic; Neurotransmitter Agents; Norepinephrine; Nutrition Disorders; Phenylalanine; Rats; Rats, Sprague-Dawley; Reference Values; Serotonin; Tyrosine; Uremia | 1996 |
The immobilized porcine pancreatic exopeptidases and its application in casein hydrolysates debittering.
Topics: Ammonium Sulfate; Animals; Arginine; Caseins; Chitin; Chromatography, High Pressure Liquid; Chymotrypsin; Decapoda; Enzymes, Immobilized; Exopeptidases; Glutamine; Glutaral; Histidine; Humans; Hydrolysis; Leucine; Lysine; Pancreas; Peptide Hydrolases; Phenylalanine; Swine; Taste; Trypsin; Tyrosine | 1996 |
Conformational restriction of Tyr and Phe side chains in opioid peptides: information about preferred and bioactive side-chain topology.
Topics: Amino Acid Sequence; Analgesics, Opioid; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oligopeptides; Opioid Peptides; Phenylalanine; Protein Binding; Protein Conformation; Receptors, Opioid; Stereoisomerism; Tyrosine | 1996 |
Decrease in plasma phenylalanine and tyrosine after phenylalanine-tyrosine free amino acid solutions in man.
Topics: Adult; Blood Pressure; Catecholamines; Humans; Male; Phenylalanine; Tyrosine | 1996 |
The role of the T-loop of the signal transducing protein PII from Escherichia coli.
Topics: Amino Acid Sequence; Bacteria; Bacterial Proteins; Base Sequence; Crystallography, X-Ray; DNA Primers; Escherichia coli; Kinetics; Macromolecular Substances; Models, Structural; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; PII Nitrogen Regulatory Proteins; Plasmids; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Software; Tyrosine; UDPglucose-Hexose-1-Phosphate Uridylyltransferase; Uridine | 1996 |
Unaccustomed high-mileage vs intensity training-related changes in performance and serum amino acid levels.
Topics: Adult; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cystine; Erythrocyte Count; Exercise Test; Fatigue; Glycine; Hematocrit; Hemoglobins; Humans; Lactates; Leukocyte Count; Lysine; Methionine; Phenylalanine; Physical Endurance; Prospective Studies; Running; Serine; Taurine; Tryptophan; Tyrosine | 1996 |
Role of strong anchor residues in the effective binding of 10-mer and 11-mer peptides to HLA-A*2402 molecules.
Topics: Binding Sites; Flow Cytometry; HLA-A Antigens; HLA-A24 Antigen; Humans; Isoleucine; Leucine; Peptides; Phenylalanine; Structure-Activity Relationship; Tyrosine | 1996 |
Replacement of the conserved tyrosine 1210 by phenylalanine in the insulin receptor affects insulin-induced dephosphorylation of focal adhesion kinase but leaves other responses intact.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Adhesion Molecules; CHO Cells; Conserved Sequence; Cricetinae; DNA Primers; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Glycogen; Insulin; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Binding; Protein-Tyrosine Kinases; Receptor, Insulin; Temperature; Tyrosine | 1996 |
Donor-side photoinhibition in photosystem II from Chlamydomonas reinhardtii upon mutation of tyrosine-Z in the D1 polypeptide to phenylalanine.
Topics: Algal Proteins; Animals; Base Sequence; Carboxypeptidases; Carotenoids; Catalase; Chlamydomonas reinhardtii; Chlorophyll; Endopeptidases; Ferricyanides; Fluorescence; Free Radicals; Light-Harvesting Protein Complexes; Molecular Sequence Data; Oxidation-Reduction; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Proprotein Convertases; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase; Tyrosine | 1996 |
In vivo amino acid metabolism of gut and liver during short and prolonged starvation.
Topics: Acute Disease; Animals; Biological Transport; Chronic Disease; Intestinal Mucosa; Liver; Liver Circulation; Male; Phenylalanine; Portal Vein; Proteins; Rats; Rats, Inbred Lew; Starvation; Tyrosine; Viscera | 1996 |
Determination of the Neurospora crassa CYS 3 sulfur regulatory protein consensus DNA-binding site: amino-acid substitutions in the CYS3 bZIP domain that alter DNA-binding specificity.
Topics: Amino Acid Sequence; Conserved Sequence; Cystathionine gamma-Lyase; DNA-Binding Proteins; DNA, Fungal; Mutagenesis, Site-Directed; Mutation; Neurospora crassa; Phenylalanine; Saccharomyces cerevisiae Proteins; Serine; Transcription Factors; Tyrosine | 1996 |
Sulfated cyclodextrins for the chiral separations of catecholamines and related compounds in the reversed electrophoretic polarity mode.
Topics: Binding Sites; Capillary Action; Catecholamines; Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis; Epinephrine; Indicators and Reagents; Kinetics; Models, Chemical; Norepinephrine; Phenylalanine; Stereoisomerism; Sulfuric Acids; Tyrosine | 1996 |
Interactions of oxime reactivators with diethylphosphoryl adducts of human acetylcholinesterase and its mutant derivatives.
Topics: Acetylcholinesterase; Amino Acid Sequence; Binding Sites; Cholinesterase Inhibitors; Cholinesterase Reactivators; Humans; Kinetics; Mutagenesis, Site-Directed; Organophosphorus Compounds; Oximes; Paraoxon; Phenylalanine; Point Mutation; Recombinant Proteins; Trimedoxime; Tryptophan; Tyrosine | 1996 |
Active site-directed double mutants of dihydrofolate reductase.
Topics: 3T3 Cells; Animals; Binding Sites; Folic Acid Antagonists; Genetic Variation; Humans; Kinetics; Mice; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Tyrosine | 1996 |
Activation of a recombinant membrane type 1-matrix metalloproteinase (MT1-MMP) by furin and its interaction with tissue inhibitor of metalloproteinases (TIMP)-2.
Topics: Arginine; Binding Sites; Enzyme Activation; Enzyme Precursors; Furin; Gelatinases; Glycoproteins; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Phenylalanine; Protease Inhibitors; Proteins; Recombinant Fusion Proteins; Subtilisins; Thiophenes; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tyrosine | 1996 |
Identification of tyrosine 187 as a protein kinase C-delta phosphorylation site.
Topics: 3T3 Cells; Animals; DNA, Complementary; Electrophoresis, Gel, Two-Dimensional; Isoenzymes; Mice; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Kinase C-delta; Substrate Specificity; Tetradecanoylphorbol Acetate; Transfection; Tyrosine | 1996 |
Neurotransmitter positron emission tomographic-studies in adults with phenylketonuria, a pilot study.
Topics: Adolescent; Adult; Brain; Carbon Radioisotopes; Female; Humans; Male; Phenylalanine; Phenylketonurias; Pilot Projects; Spiperone; Tomography, Emission-Computed; Tyrosine | 1996 |
Mutations of Tyr326 in the beta 2-adrenoceptor disrupt multiple receptor functions.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Alanine; Animals; Cell Membrane; CHO Cells; Cloning, Molecular; Cricetinae; Gene Expression; Humans; Iodine Radioisotopes; Isoproterenol; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Pindolol; Protein Binding; Radioligand Assay; Receptors, Adrenergic, beta-2; Transfection; Tyrosine | 1996 |
Placental tyrosine transport and maternal phenylketonuria.
Topics: Cell Membrane; Culture Techniques; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Microvilli; Phenylalanine; Placenta; Pregnancy; Trophoblasts; Tyrosine | 1996 |
Tyrosine and phenylalanine restriction sensitizes adriamycin-resistant P388 leukemia cells to adriamycin.
Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Doxorubicin; Drug Resistance, Neoplasm; Leukemia P388; Melanoma, Experimental; Mice; Phenylalanine; Tumor Cells, Cultured; Tyrosine; Verapamil | 1996 |
Action on bovine alpha s1-casein of cardosins A and B, aspartic proteinases from the flowers of the cardoon Cynara cardunculus L.
Topics: Animals; Arginine; Aspartic Acid Endopeptidases; Caseins; Cattle; Molecular Weight; Peptide Fragments; Phenylalanine; Plant Proteins; Plants; Sequence Analysis; Substrate Specificity; Tryptophan; Tyrosine | 1996 |
Characterization of dynamic state inhibitors of HIV-1 protease.
Topics: Amino Acid Sequence; Binding Sites; HIV Protease; HIV Protease Inhibitors; Kinetics; Models, Chemical; Molecular Sequence Data; Molecular Structure; Nitriles; Phenylalanine; Protein Binding; Structure-Activity Relationship; Tyrosine | 1995 |
Cation-pi interactions in aromatics of biological and medicinal interest: electrostatic potential surfaces as a useful qualitative guide.
Topics: Benzene; Benzene Derivatives; Cations, Monovalent; Computer Simulation; Gases; Histidine; Models, Molecular; Phenylalanine; Sodium; Static Electricity; Tryptophan; Tyrosine | 1996 |
Protein degradation and synthesis measured with multiple amino acid tracers in vivo.
Topics: Adult; Amino Acids; Female; Humans; Insulin; Leucine; Male; Oxidation-Reduction; Phenylalanine; Proteins; Tyrosine | 1996 |
Time-resolved fluorescence. An approach in protein analysis.
Topics: Animals; Cattle; Humans; Models, Theoretical; Phenylalanine; Proteins; Sensitivity and Specificity; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Time Factors; Tryptophan; Tyrosine | 1996 |
A negative regulatory region in the intracellular domain of the human interferon-alpha receptor.
Topics: Animals; Fibroblasts; Humans; Mice; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Receptor, Interferon alpha-beta; Receptors, Interferon; Structure-Activity Relationship; Transfection; Tyrosine | 1996 |
Increased contribution by myofibrillar protein to whole-body protein breakdown according to severity of surgical stress.
Topics: Alanine; Amino Acids; Amino Acids, Branched-Chain; Catecholamines; Cohort Studies; Colectomy; Digestive System Surgical Procedures; Esophageal Neoplasms; Esophagectomy; Gastrectomy; Glutamine; Humans; Male; Methylhistidines; Middle Aged; Muscle Proteins; Myofibrils; Parenteral Nutrition, Total; Phenylalanine; Postoperative Period; Stress, Physiological; Tyrosine | 1996 |
PhhR, a divergently transcribed activator of the phenylalanine hydroxylase gene cluster of Pseudomonas aeruginosa.
Topics: Amino Acid Sequence; Bacterial Proteins; Base Sequence; beta-Galactosidase; Blotting, Western; Cloning, Molecular; Culture Media; DNA-Binding Proteins; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Escherichia coli Proteins; Fructose; Gene Expression Regulation, Bacterial; Glucose; Haemophilus influenzae; Introns; Lac Operon; Molecular Sequence Data; Operon; Phenylalanine; Phenylalanine Hydroxylase; Plasmids; Promoter Regions, Genetic; Pseudomonas aeruginosa; Recombination, Genetic; Repressor Proteins; RNA Polymerase Sigma 54; Sequence Alignment; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sigma Factor; Terminator Regions, Genetic; Trans-Activators; Transcription, Genetic; Tyrosine | 1996 |
Study of tyrosine-containing mutants of ribosomal protein L7/L12 from Escherichia coli.
Topics: Bacterial Proteins; Calorimetry, Differential Scanning; Circular Dichroism; Dialysis; Escherichia coli; Hydrogen-Ion Concentration; Mutation; Phenylalanine; Protein Denaturation; Ribosomal Proteins; Spectrophotometry, Ultraviolet; Temperature; Tyrosine | 1996 |
Perturbed interaction between residues 85 and 204 in Tyr-185-->Phe and Asp-85-->Glu bacteriorhodopsins.
Topics: Aspartic Acid; Bacteriorhodopsins; Darkness; Glutamic Acid; Halobacterium; Hydrogen-Ion Concentration; Kinetics; Light; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Recombinant Proteins; Spectrophotometry; Tyrosine | 1996 |
Tyrosine-599 of the c-Mpl receptor is required for Shc phosphorylation and the induction of cellular differentiation.
Topics: Animals; Cell Differentiation; Cell Division; Cell Line; DNA Primers; Humans; Mice; Mutagenesis, Site-Directed; Neoplasm Proteins; Phenylalanine; Phosphorylation; Point Mutation; Polymerase Chain Reaction; Proto-Oncogene Proteins; Receptors, Cytokine; Receptors, Thrombopoietin; Recombinant Proteins; Sequence Deletion; Signal Transduction; Thrombopoietin; Transfection; Tumor Cells, Cultured; Tyrosine | 1996 |
Whole body protein metabolism in children with cancer.
Topics: Adolescent; Amino Acids; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Kinetics; Leucine; Male; Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Tyrosine | 1996 |
Functional interaction between the SH2 domain of Fyn and tyrosine 324 of hamster polyomavirus middle-T antigen.
Topics: 3T3 Cells; Animals; Antigens, Polyomavirus Transforming; Cricetinae; Mice; Phenylalanine; Point Mutation; Polyomavirus; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Rabbits; src Homology Domains; Transformation, Genetic; Tyrosine | 1997 |
Conferring RNA polymerase activity to a DNA polymerase: a single residue in reverse transcriptase controls substrate selection.
Topics: Binding Sites; DNA-Directed DNA Polymerase; DNA-Directed RNA Polymerases; Kinetics; Models, Molecular; Moloney murine leukemia virus; Phenylalanine; Point Mutation; RNA-Directed DNA Polymerase; Substrate Specificity; Tyrosine; Valine | 1997 |
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
Topics: Animals; Aorta; Arteriosclerosis; Cattle; Copper; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyl Radical; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine | 1997 |
Hydroxyl radical generation by rheumatoid blood and knee joint synovial fluid.
Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Knee Joint; Phenylalanine; Synovial Fluid; Tyrosine | 1996 |
Continuous 24-h L-[1-13C]phenylalanine and L-[3,3-2H2]tyrosine oral-tracer studies at an intermediate phenylalanine intake to estimate requirements in adults.
Topics: Administration, Oral; Adult; Breath Tests; Calorimetry, Indirect; Carbon Dioxide; Circadian Rhythm; Fasting; Humans; Hydroxylation; Infusions, Intravenous; Kinetics; Leucine; Male; Nutritional Requirements; Phenylalanine; Tyrosine | 1997 |
Mutational analysis of the feedback sites of phenylalanine-sensitive 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase of Escherichia coli.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Cloning, Molecular; DNA Mutational Analysis; Dose-Response Relationship, Drug; Escherichia coli; Feedback; Isoenzymes; Phenylalanine; Sequence Analysis, DNA; Tryptophan; Tyrosine | 1997 |
Mutant RecA proteins which form hexamer-sized oligomers.
Topics: Arginine; Asparagine; Bacteria; Chromatography, Liquid; Crystallography, X-Ray; DNA Repair; Lysine; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Rec A Recombinases; Tyrosine | 1997 |
[125I]Iberiotoxin-D19Y/Y36F, the first selective, high specific activity radioligand for high-conductance calcium-activated potassium channels.
Topics: Amino Acid Sequence; Animals; Aspartic Acid; Calcium; Cattle; Female; Iodine Radioisotopes; Molecular Sequence Data; Muscle, Smooth; Oxidation-Reduction; Peptides; Phenylalanine; Potassium Channels; Protein Binding; Radioligand Assay; Recombinant Proteins; Sarcolemma; Trachea; Tyrosine; Xenopus laevis | 1997 |
A single amino acid substitution in Staphylococcus aureus dihydrofolate reductase determines trimethoprim resistance.
Topics: Binding Sites; Chromosomes, Bacterial; Crystallography, X-Ray; Humans; Models, Molecular; Molecular Conformation; NADP; Phenylalanine; Point Mutation; Protein Conformation; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase; Trimethoprim; Trimethoprim Resistance; Tyrosine | 1997 |
Mutational analysis of the adeno-associated virus Rep68 protein: identification of critical residues necessary for site-specific endonuclease activity.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; ATP-Binding Cassette Transporters; Carrier Proteins; Dependovirus; DNA Helicases; DNA-Binding Proteins; Endonucleases; Escherichia coli Proteins; Humans; Maltose-Binding Proteins; Molecular Sequence Data; Monosaccharide Transport Proteins; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Fusion Proteins; Tyrosine; Viral Proteins | 1997 |
STAT5 activation correlates with erythropoietin receptor-mediated erythroid differentiation of an erythroleukemia cell line.
Topics: Animals; Cell Differentiation; DNA-Binding Proteins; DNA, Complementary; Erythroid Precursor Cells; Friend murine leukemia virus; Janus Kinase 2; Leukemia, Erythroblastic, Acute; Milk Proteins; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Recombinant Fusion Proteins; STAT5 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1997 |
Site-directed mutagenesis of the aspartokinase gene lysC and its characterization in Brevibacterium flavum.
Topics: Aspartate Kinase; Brevibacterium; DNA, Bacterial; Escherichia coli; Gene Expression Regulation, Bacterial; Mutagenesis, Site-Directed; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Serine; Transformation, Genetic; Tyrosine | 1997 |
D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Dipeptides; Drug Resistance, Microbial; Lactates; Leuconostoc; Models, Molecular; Molecular Sequence Data; Peptide Synthases; Phenotype; Phenylalanine; Point Mutation; Sequence Alignment; Tyrosine; Vancomycin | 1997 |
Phenylalanine requirements determined by using L-[1-14C]phenylalanine in neonatal piglets receiving total parenteral nutrition supplemented with tyrosine.
Topics: Amino Acids; Animals; Animals, Newborn; Carbon Dioxide; Carbon Radioisotopes; Energy Metabolism; Linear Models; Male; Models, Biological; Nutritional Requirements; Oxidation-Reduction; Parenteral Nutrition, Total; Phenylalanine; Random Allocation; Swine; Tyrosine | 1997 |
Alkaptonuria: from humans to moulds and back.
Topics: Alkaptonuria; Aspergillus nidulans; Dioxygenases; History, 20th Century; Homogentisate 1,2-Dioxygenase; Humans; Oxygenases; Phenylalanine; Tyrosine | 1997 |
Tyrosine kinetics and requirements during total parenteral nutrition in the neonatal piglet: the effect of glycyl-L-tyrosine supplementation.
Topics: Amino Acids; Animals; Animals, Newborn; Dipeptides; Kinetics; Male; Milk Proteins; Nutritional Requirements; Oxidation-Reduction; Parenteral Nutrition, Total; Phenylalanine; Stochastic Processes; Swine; Tyrosine | 1997 |
Conformations and orientations of aromatic amino acid residues of tachyplesin I in phospholipid membranes.
Topics: Amino Acid Sequence; Amino Acids; Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Circular Dichroism; DNA-Binding Proteins; Fluorescence Polarization; Horseshoe Crabs; Kinetics; Liposomes; Models, Molecular; Molecular Sequence Data; Peptides, Cyclic; Phenylalanine; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1997 |
High-performance liquid chromatography on-line derivative spectroscopy for the characterization of peptides with aromatic amino acid residues.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Mathematics; Peptide Fragments; Phenylalanine; Phosphotyrosine; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1997 |
The conserved residue tyrosine 34 is essential for maximal activity of iron-superoxide dismutase from Escherichia coli.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Escherichia coli; Hydrogen-Ion Concentration; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Restriction Mapping; Serine; Structure-Activity Relationship; Superoxide Dismutase; Tyrosine | 1997 |
Reconstitution of T cell antigen receptor-induced Erk2 kinase activation in Lck-negative JCaM1 cells by Syk.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; DNA-Binding Proteins; Enzyme Activation; Enzyme Precursors; Genes, Reporter; Humans; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Luciferases; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Mitogen-Activated Protein Kinase 1; Mutagenesis, Site-Directed; NFATC Transcription Factors; Nuclear Proteins; Oncogene Proteins, Viral; Phenylalanine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; src Homology Domains; src-Family Kinases; Syk Kinase; Transcription Factors; Tyrosine | 1997 |
Amino acids suppress proteolysis independent of insulin throughout the neonatal period.
Topics: Aging; Amino Acids; Blood Glucose; Humans; Hydroxylation; Infant, Newborn; Infusions, Intravenous; Insulin; Leucine; Osmolar Concentration; Oxidation-Reduction; Peptide Hydrolases; Phenylalanine; Protease Inhibitors; Tyrosine | 1997 |
Stimulation of aryl metabolite production in the basidiomycete Bjerkandera sp. strain BOS55 with biosynthetic precursors and lignin degradation products.
Topics: Basidiomycota; Benzaldehydes; Benzoates; Benzoin; Benzyl Alcohols; Chlorobenzoates; Hydroxybenzoates; Lignin; Manganese; Parabens; Phenylalanine; Tyrosine | 1997 |
Structure/function relationship study of Tyr14 and Arg22 in trichosanthin, a ribosome-inactivating protein.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Anti-HIV Agents; Arginine; Binding Sites; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Biosynthesis; Protein Synthesis Inhibitors; Rabbits; Ribosomes; Stereoisomerism; Structure-Activity Relationship; Trichosanthin; Tyrosine | 1997 |
Oral phenylalanine loading in dopa-responsive dystonia: a possible diagnostic test.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Biopterins; Child, Preschool; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; Female; Humans; Male; Middle Aged; Neopterin; Osmolar Concentration; Phenylalanine; Time Factors; Tyrosine | 1997 |
The crystal structure of Citrobacter freundii tyrosine phenol-lyase complexed with 3-(4'-hydroxyphenyl)propionic acid, together with site-directed mutagenesis and kinetic analysis, demonstrates that arginine 381 is required for substrate specificity.
Topics: Arginine; Catalysis; Citrobacter freundii; Crystallization; Crystallography, X-Ray; Isoleucine; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Phenylpropionates; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Tyrosine Phenol-Lyase; Valine | 1997 |
Antimicrobial activity of viridiofungins.
Topics: Antifungal Agents; Bridged Bicyclo Compounds, Heterocyclic; Citrates; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Fermentation; Microbial Sensitivity Tests; Phenylalanine; Tricarboxylic Acids; Tryptophan; Tyrosine | 1997 |
Viridiofungins, novel inhibitors of sphingolipid synthesis.
Topics: Acyltransferases; Antifungal Agents; Citrates; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Microbial Sensitivity Tests; Phenylalanine; Serine C-Palmitoyltransferase; Sphingolipids; Tryptophan; Tyrosine | 1997 |
Two distinct oncornaviruses harbor an intracytoplasmic tyrosine-based basolateral targeting signal in their viral envelope glycoprotein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Line; Cytoplasm; Dogs; Gene Products, env; Glycoproteins; HIV-1; Human T-lymphotropic virus 1; Humans; Jurkat Cells; Mice; Molecular Sequence Data; Moloney murine leukemia virus; Phenylalanine; Point Mutation; Serine; Tyrosine | 1997 |
Tyrosine residues in the C-terminal domain of the insulin-like growth factor-I receptor mediate mitogenic and tumorigenic signals.
Topics: 3T3 Cells; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Transformation, Neoplastic; Clone Cells; Histidine; Humans; Insulin Receptor Substrate Proteins; Mice; Mitosis; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Receptor, IGF Type 1; src Homology Domains; Structure-Activity Relationship; Tyrosine | 1997 |
Mutation of tyrosine 34 to phenylalanine eliminates the active site pK of reduced iron-containing superoxide dismutase.
Topics: Binding Sites; Electrochemistry; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyl Radical; Iron; Magnetic Resonance Spectroscopy; Mutation; Oxidation-Reduction; Phenylalanine; Superoxide Dismutase; Tyrosine | 1997 |
Roles of JAK kinase in human GM-CSF receptor signals.
Topics: Cell Division; Cell Line; Genes, fos; Genes, myc; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-myc; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Recombinant Proteins; Sequence Deletion; Signal Transduction; Transfection; Tyrosine | 1997 |
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.
Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; DNA-Binding Proteins; Erythropoietin; Inositol Polyphosphate 5-Phosphatases; Milk Proteins; Models, Biological; Mutagenesis, Site-Directed; Phenylalanine; Phosphoric Monoester Hydrolases; Phosphorylation; Receptors, Erythropoietin; Recombinant Proteins; src Homology Domains; STAT5 Transcription Factor; Trans-Activators; Tyrosine | 1997 |
Ovulation rate and the concentrations of LH, FSH, GH, prolactin and insulin in ewes infused with tryptophan, tyrosine or tyrosine plus phenylalanine during the luteal phase of the oestrous cycle.
Topics: Animals; Female; Follicle Stimulating Hormone; Growth Hormone; Infusions, Intravenous; Insulin; Luteal Phase; Luteinizing Hormone; Ovulation; Phenylalanine; Prolactin; Sheep; Tryptophan; Tyrosine | 1997 |
Mutational analysis of the BPTI folding pathway: I. Effects of aromatic-->leucine substitutions on the distribution of folding intermediates.
Topics: Animals; Aprotinin; Cattle; Chromatography, High Pressure Liquid; Disulfides; DNA Mutational Analysis; Escherichia coli; Leucine; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Oxidation-Reduction; Phenylalanine; Protein Conformation; Protein Denaturation; Protein Folding; Recombinant Proteins; Tyrosine | 1997 |
Mutational analysis of the BPTI folding pathway: II. Effects of aromatic-->leucine substitutions on folding kinetics and thermodynamics.
Topics: Alkylation; Animals; Aprotinin; Cattle; Cystine; Disulfides; DNA Mutational Analysis; Escherichia coli; Kinetics; Leucine; Models, Chemical; Oxidation-Reduction; Phenylalanine; Protein Denaturation; Protein Folding; Recombinant Proteins; Thermodynamics; Tyrosine | 1997 |
Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Cell Line; Cell Membrane; COS Cells; DNA-Binding Proteins; Ephrin-B1; GTPase-Activating Proteins; Humans; Membrane Proteins; Mice; Molecular Sequence Data; Neurons; Oncogene Proteins; Phenylalanine; Phosphoproteins; Phosphorylation; Proteins; ras GTPase-Activating Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, EphB2; Recombinant Fusion Proteins; RNA-Binding Proteins; Signal Transduction; src Homology Domains; Tyrosine | 1997 |
Model of milk protein synthesis. A mechanistic model of milk protein synthesis in the lactating bovine mammary gland.
Topics: Amino Acids; Animals; Biological Transport; Cattle; Female; Mammary Glands, Animal; Milk Proteins; Models, Biological; Phenylalanine; Protein Biosynthesis; Transcription, Genetic; Tyrosine | 1997 |
PLC-gamma activation is required for PDGF-betaR-mediated mitogenesis and monocytic differentiation of myeloid progenitor cells.
Topics: Binding Sites; Cell Differentiation; DNA; Enzyme Activation; Enzyme Inhibitors; Humans; Indoles; Isoenzymes; Maleimides; Monocytes; Mutation; Phenylalanine; Phospholipase C gamma; Phosphorylation; Platelet-Derived Growth Factor; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Stem Cells; Type C Phospholipases; Tyrosine | 1997 |
Protein-induced increase in urinary dopamine in normal and diabetic rats: role of catecholamine precursors.
Topics: Animal Feed; Animals; Diabetes Mellitus, Experimental; Diet, Protein-Restricted; Dietary Proteins; Dopamine; Fasting; Male; Phenylalanine; Rats; Rats, Sprague-Dawley; Tyrosine | 1997 |
A mutation in the 14 alpha-demethylase gene of Uncinula necator that correlates with resistance to a sterol biosynthesis inhibitor.
Topics: Alleles; Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Fungi; Fungicides, Industrial; Molecular Sequence Data; Oxidoreductases; Phenylalanine; Point Mutation; Polymerase Chain Reaction; Sterol 14-Demethylase; Sterols; Triazoles; Tyrosine | 1997 |
Tyrosyl interactions in the folding and unfolding of bovine pancreatic ribonuclease A: a study of tyrosine-to-phenylalanine mutants.
Topics: Animals; Cattle; Guanidine; Guanidines; Hydrogen-Ion Concentration; Hydrolysis; Isomerism; Kinetics; Mutagenesis, Site-Directed; Pancreas; Phenylalanine; Protein Folding; Ribonuclease, Pancreatic; Thermodynamics; Tyrosine | 1997 |
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase.
Topics: Amino Acids; Dopa Decarboxylase; Esters; Hydrogen-Ion Concentration; Methylation; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Tyrosine | 1997 |
Identification of conserved aromatic residues essential for agonist binding and second messenger production at 5-hydroxytryptamine2A receptors.
Topics: Animals; Binding Sites; Bufotenin; COS Cells; DOM 2,5-Dimethoxy-4-Methylamphetamine; Ligands; Phenylalanine; Phosphatidylinositols; Protein Structure, Secondary; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Second Messenger Systems; Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Tryptophan; Tyrosine | 1997 |
Distinct tyrosine autophosphorylation sites negatively and positively modulate neu-mediated transformation.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Catalysis; Cell Transformation, Neoplastic; ErbB Receptors; GRB2 Adaptor Protein; Mice; Models, Biological; Mutagenesis; Phenylalanine; Phosphorylation; Proteins; ras Proteins; Receptor, ErbB-2; Signal Transduction; src Homology Domains; Tyrosine | 1997 |
Mutagenesis of residues 27 and 78 modulates heme orientation in cytochrome b5.
Topics: Amino Acid Sequence; Animals; Cattle; Crystallography, X-Ray; Cytochromes b5; Heme; Magnetic Resonance Spectroscopy; Microsomes; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotiana; Phenylalanine; Plants, Toxic; Rats; Tyrosine | 1997 |
Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16.
Topics: Animals; Arginine; Binding Sites; Cattle; Crystallography, X-Ray; Fibrinopeptide A; Molecular Sequence Data; Phenylalanine; Point Mutation; Protein Binding; Protein Conformation; Thrombin; Tyrosine | 1997 |
Hydroxyl radical generation in oxygen-treated infants.
Topics: Apgar Score; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Infant, Newborn; Infant, Newborn, Diseases; Oxygen; Oxygen Inhalation Therapy; Phenylalanine; Regression Analysis; Tyrosine | 1997 |
Mapping the kidney potassium channel ROMK1. Glycosylation of the pore signature sequence and the COOH terminus.
Topics: Amino Acid Sequence; Animals; Barium; Cell Line; Cell Membrane; Conserved Sequence; Glycosylation; Kidney; Membrane Potentials; Models, Structural; Multigene Family; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Polymerase Chain Reaction; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Conformation; Recombinant Proteins; Spodoptera; Transfection; Tunicamycin; Tyrosine | 1997 |
Metal-dependent conformers of the periplasmic ferric ion binding protein.
Topics: Amino Acid Substitution; Apoproteins; Bacterial Outer Membrane Proteins; Bacterial Proteins; Binding Sites; Carrier Proteins; Cloning, Molecular; Escherichia coli; Iron; Iron-Binding Proteins; Mutagenesis, Site-Directed; Periplasmic Binding Proteins; Phenylalanine; Protein Conformation; Recombinant Proteins; Spectrophotometry; Trypsin; Tyrosine | 1997 |
Activation of protein kinase C-alpha isoform in murine melanoma cells with high metastatic potential.
Topics: Animals; Cathepsin B; Cell Culture Techniques; DNA, Neoplasm; Enzyme Activation; Isoenzymes; Melanoma, Experimental; Mice; Neoplasm Metastasis; Phenylalanine; Protein Kinase C; Tumor Cells, Cultured; Tyrosine | 1997 |
Correcting the circular dichroism spectra of peptides for contributions of absorbing side chains.
Topics: Amino Acid Sequence; Circular Dichroism; Cysteine; Methionine; Molecular Sequence Data; Peptides; Phenylalanine; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 1997 |
Reactivity of the tyrosyl radical of Escherichia coli ribonucleotide reductase -- control by the protein.
Topics: Amino Acid Substitution; Ascorbic Acid; Binding Sites; Crystallography, X-Ray; Dithionite; Escherichia coli; Free Radical Scavengers; Free Radicals; Hydrazines; Hydroxyurea; Kinetics; Leucine; Models, Structural; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenols; Phenylalanine; Protein Conformation; Recombinant Proteins; Ribonucleotide Reductases; Substrate Specificity; Tyrosine | 1997 |
Variable regions A and B in the envelope glycoproteins of feline leukemia virus subgroup B and amphotropic murine leukemia virus interact with discrete receptor domains.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carrier Proteins; Cats; Cell Line; Glycoproteins; Leukemia Virus, Feline; Leukemia Virus, Murine; Molecular Sequence Data; Phenylalanine; Proline; Receptors, Virus; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Sodium-Phosphate Cotransporter Proteins; Sodium-Phosphate Cotransporter Proteins, Type III; Structure-Activity Relationship; Symporters; Tyrosine; Valine; Viral Envelope Proteins; Virion | 1997 |
Organizing and computing metabolic pathway data in terms of binary relations.
Topics: Animals; Computer Simulation; Computing Methodologies; Databases as Topic; Enzymes; Genes; Haemophilus influenzae; Information Storage and Retrieval; MEDLINE; Metabolism; Models, Biological; Phenylalanine; Programming Languages; Tryptophan; Tyrosine | 1997 |
May peripheral and central fatigue be correlated? Can we monitor them by means of clinical laboratory tools?
Topics: Adult; Amino Acids; Amino Acids, Branched-Chain; Biomarkers; Chromatography, High Pressure Liquid; Fatigue; Fatty Acids; Follow-Up Studies; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Hypoxanthine; Immunoenzyme Techniques; Inosine; Male; Muscle Fatigue; Phenylalanine; Physical Exertion; Purines; Serotonin; Tryptophan; Tyrosine; Xanthine | 1997 |
Delta-opiate DPDPE in magnetically oriented phospholipid micelles: binding and arrangement of aromatic pharmacophores.
Topics: Biophysical Phenomena; Biophysics; Carbon Isotopes; Dimyristoylphosphatidylcholine; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hydrogen; Lipid Bilayers; Magnetic Resonance Spectroscopy; Magnetics; Micelles; Models, Molecular; Phenylalanine; Phospholipid Ethers; Phospholipids; Protein Conformation; Receptors, Opioid, delta; Tyrosine | 1997 |
Prefrontal cortex cognitive deficits in children treated early and continuously for PKU.
Topics: Age Factors; Analysis of Variance; Attention; Case-Control Studies; Child; Child, Preschool; Cognition Disorders; Cross-Sectional Studies; Female; Humans; Infant; Inhibition, Psychological; Intelligence; Longitudinal Studies; Male; Memory; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Regression Analysis; Sex Factors; Tyrosine; Volition | 1997 |
Tyrosine and phenylalanine restriction induces G0/G1 cell cycle arrest in murine melanoma in vitro and in vivo.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cell Cycle; Culture Media; Cyclins; Diet; Female; Flow Cytometry; Immune Sera; Melanoma, Experimental; Methionine; Mice; Phenylalanine; Proliferating Cell Nuclear Antigen; Rabbits; Rats; Specific Pathogen-Free Organisms; Time Factors; Tumor Cells, Cultured; Tyrosine | 1997 |
Effects of cachexia due to cancer on whole body and skeletal muscle protein turnover.
Topics: Adult; Aged; Blood Proteins; Cachexia; Carbon Isotopes; Carcinoma; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Muscle, Skeletal; Nutrition Disorders; Phenylalanine; Protein Biosynthesis; Proteins; Radiopharmaceuticals; Stomach Neoplasms; Tyrosine | 1998 |
Expression and characterization of the catalytic domain of human phenylalanine hydroxylase.
Topics: Binding Sites; Biopterins; Catalysis; Chromatography, High Pressure Liquid; Copper; Enzyme Activation; Escherichia coli; Ferrous Compounds; Humans; Iron; Kinetics; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Recombinant Proteins; Tyrosine | 1997 |
Melanin-concentrating hormone binding sites in human SVK14 keratinocytes.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carcinoma, Squamous Cell; Cell Line, Transformed; Cell Membrane; Humans; Hypothalamic Hormones; Iodine Radioisotopes; Keratinocytes; Melanins; Melanoma; Molecular Sequence Data; Neuroglia; PC12 Cells; Phenylalanine; Pituitary Hormones; Radioligand Assay; Rats; Receptors, Pituitary Hormone; Tumor Cells, Cultured; Tyrosine | 1997 |
Residue 116 determines the C-terminal anchor residue of HLA-B*3501 and -B*5101 binding peptides but does not explain the general affinity difference.
Topics: Binding Sites; Cell Line; HLA-B Antigens; HLA-B35 Antigen; HLA-B51 Antigen; Humans; Methionine; Mutagenesis, Site-Directed; Peptides; Phenylalanine; Serine; Transfection; Tyrosine | 1998 |
Redundant and selective roles for erythropoietin receptor tyrosines in erythropoiesis in vivo.
Topics: Animals; Cell Line; Erythropoiesis; Erythropoietin; Gene Expression; Gene Transfer Techniques; Mice; Mutagenesis; Phenylalanine; Receptors, Erythropoietin; Recombinant Proteins; Retroviridae; Signal Transduction; Structure-Activity Relationship; Tyrosine | 1998 |
De novo mutation of the myelin Po gene in Déjérine-Sottas disease (hereditary motor and sensory neuropathy type III): two amino acid insertion after Asp 118.
Topics: Alleles; Amino Acid Sequence; Base Sequence; DNA; DNA Mutational Analysis; Family Health; Fatal Outcome; Female; Hereditary Sensory and Motor Neuropathy; Humans; Infant; Male; Mutagenesis, Insertional; Mutation; Myelin P0 Protein; Pedigree; Phenylalanine; Polymerase Chain Reaction; Tyrosine | 1998 |
Mutations in the nucleotide binding domain of the alpha subunits of the F1-ATPase from thermophilic Bacillus PS3 that affect cross-talk between nucleotide binding sites.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum; Arginine; Bacillus; Bacterial Proteins; Binding Sites; Cysteine; Fluorine; Hydrolysis; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Proton-Translocating ATPases; Structure-Activity Relationship; Tyrosine | 1998 |
Electron injection through a specific pathway determines the outcome of oxygen activation at the diiron cluster in the F208Y mutant of Escherichia coli ribonucleotide reductase protein R2.
Topics: Ascorbic Acid; Catechols; Electron Spin Resonance Spectroscopy; Electron Transport; Escherichia coli; Iron; Metalloproteins; Mutation; Oxygen; Phenylalanine; Recombinant Proteins; Ribonucleotide Reductases; Spectrophotometry; Spectroscopy, Mossbauer; Tyrosine | 1998 |
Endopeptidase activities of selected Porphyromonas spp., Prevotella spp. and Fusobacterium spp. of oral and non-oral origin.
Topics: Alanine; Aminopeptidases; Bacteroides; Chymotrypsin; Coumarins; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Endopeptidases; Fluorescent Dyes; Fusobacterium; Fusobacterium necrophorum; Humans; Indicators and Reagents; Lysine; Mouth; Oligopeptides; Pancreatic Elastase; Phenylalanine; Porphyromonas; Porphyromonas gingivalis; Prevotella; Proline; Tyrosine; Virulence | 1997 |
UV resonance Raman spectroscopy of DNA and protein constituents of viruses: assignments and cross sections for excitations at 257, 244, 238, and 229 nm.
Topics: Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Viruses; DNA, Viral; Phenylalanine; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Sulfates; Thymidine; Tryptophan; Tyrosine; Viral Proteins | 1998 |
Multivariate discrimination for phenylketonuria (PKU) and non-PKU hyperphenylalaninemia after analysis of newborns' dried blood-spot specimens for six amino acids by ion-exchange chromatography.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; False Positive Reactions; Genetic Testing; Homocystinuria; Humans; Infant, Newborn; Leucine; Maple Syrup Urine Disease; Multivariate Analysis; New York; Phenylalanine; Phenylketonurias; Tyrosine | 1998 |
High-performance liquid chromatographic separation of enantiomers of unusual amino acids on a teicoplanin chiral stationary phase.
Topics: Amino Acids; Chromatography, High Pressure Liquid; Isomerism; Molecular Structure; Phenylalanine; Solvents; Teicoplanin; Temperature; Tyrosine | 1998 |
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to oxidize alpha-amino acids to a family of reactive aldehydes. Mechanistic studies identifying labile intermediates along the reaction pathway.
Topics: Aldehydes; Amino Acids; Chloramines; Chlorides; Humans; Hypochlorous Acid; Lysine; Mass Spectrometry; Models, Chemical; Neutrophils; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine | 1998 |
Aromatic residues affecting permeation and gating in dSlo BK channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Electric Conductivity; Evoked Potentials; Ion Channel Gating; Kinetics; Large-Conductance Calcium-Activated Potassium Channels; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Permeability; Phenylalanine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Calcium-Activated; Protein Conformation; Protein Structure, Tertiary; Tetraethylammonium; Tyrosine; Xenopus | 1998 |
In vivo evidence for compromised phenylalanine metabolism in vitiligo.
Topics: Adolescent; Adult; Biopterins; Cells, Cultured; Female; Gene Expression; GTP Cyclohydrolase; Humans; Hydro-Lyases; Kinetics; Male; Middle Aged; Phenylalanine; Phenylalanine Hydroxylase; RNA, Messenger; Skin; Spectrum Analysis, Raman; Tyrosine; Vitiligo | 1998 |
Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination.
Topics: Amino Acids; Ammonia; Culture Media; Fungal Proteins; Genes, Fungal; Isoenzymes; Kynurenine; Lyases; Phenotype; Phenylalanine; Phenylpyruvic Acids; Saccharomyces cerevisiae; Substrate Specificity; Transaminases; Tyrosine; Urea | 1998 |
Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and II reveals a new aminotransferase subfamily.
Topics: 2-Aminoadipic Acid; Amino Acid Sequence; Amino Acids; Ammonia; Base Sequence; Cloning, Molecular; Consensus Sequence; Culture Media; DNA Replication; DNA, Fungal; Enzyme Induction; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Genetic Complementation Test; Isoenzymes; Lyases; Molecular Sequence Data; Multigene Family; Phenylalanine; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Sequence Alignment; Sequence Homology; Substrate Specificity; Transaminases; Tyrosine; Urea | 1998 |
Site-specific spin trapping of tyrosine radicals in the oxidation of metmyoglobin by hydrogen peroxide.
Topics: Amino Acid Substitution; Animals; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Horses; Hydrogen Peroxide; Metmyoglobin; Models, Chemical; Oxidation-Reduction; Phenylalanine; Protein Conformation; Spectrometry, Mass, Secondary Ion; Spin Labels; Tryptophan; Tyrosine | 1998 |
Reply to SP Bessman.
Topics: Diet; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tyrosine | 1998 |
[Effects of phenylalanine and tyrosine on cold acclimation in mice].
Topics: Acclimatization; Adipose Tissue; Animals; Blood Glucose; Body Temperature; Body Weight; Cold Temperature; Drinking; Eating; Fatty Acids, Nonesterified; Male; Mice; Mice, Inbred Strains; Organ Size; Phenylalanine; Rectum; Tyrosine | 1997 |
Investigation of the potential active site of a cyanide dihydratase using site-directed mutagenesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Base Sequence; Binding Sites; Cysteine; Hydrolases; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Pseudomonas; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine; Tyrosine | 1998 |
Determination of L-phenylalanine based on an NADH-detecting biosensor.
Topics: Amino Acid Oxidoreductases; Benzoquinones; Biosensing Techniques; Carbon; Catechols; Electrochemistry; Enzymes, Immobilized; Humans; Hydrogen-Ion Concentration; Mixed Function Oxygenases; Monophenol Monooxygenase; NAD; Phenylalanine; Tyrosine | 1998 |
Characterization of mutants of the 6'-N-acetyltransferase encoded by the multiresistance transposon Tn1331: effect of Phen171-to-Leu171 and Tyr80-to-Cys80 substitutions.
Topics: Acetylation; Acetyltransferases; Amikacin; Amino Acid Substitution; Anti-Bacterial Agents; DNA Transposable Elements; Drug Resistance, Multiple; Kanamycin; Kanamycin Resistance; Klebsiella pneumoniae; Microbial Sensitivity Tests; Mutation; Phenylalanine; Sequence Alignment; Substrate Specificity; Tyrosine | 1998 |
Biochemical characterization of the 20S proteasome from the methanoarchaeon Methanosarcina thermophila.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Archaeal Proteins; Arginine; Asparagine; Aspartic Acid; Base Sequence; Cloning, Molecular; Cysteine Endopeptidases; DNA, Archaeal; Escherichia coli; Glutamine; Ions; Lysine; Methanosarcina; Microscopy, Electron; Molecular Sequence Data; Multienzyme Complexes; Peptides; Phenylalanine; Plasmids; Polymerase Chain Reaction; Sequence Analysis, DNA; Sodium Dodecyl Sulfate; Threonine; Tyrosine | 1998 |
UV-difference and CD spectroscopy studies on juvenile hormone binding to its carrier protein.
Topics: Animals; Carrier Proteins; Circular Dichroism; Hemolymph; Insect Proteins; Larva; Moths; Phenylalanine; Protein Binding; Protein Structure, Secondary; Sesquiterpenes; Spectrophotometry, Ultraviolet; Tyrosine | 1998 |
SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.
Topics: Cell Membrane; Down-Regulation; Humans; Intracellular Signaling Peptides and Proteins; Phenylalanine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-kit; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Stem Cell Factor; Tumor Cells, Cultured; Tyrosine | 1998 |
Local control of peptide conformation: stabilization of cis proline peptide bonds by aromatic proline interactions.
Topics: Deuterium; Kinetics; Molecular Conformation; Peptides; Phenylalanine; Proline; Protein Folding; Stereoisomerism; Thermodynamics; Tyrosine | 1998 |
Asymmetrical phosphorylation and function of immunoreceptor tyrosine-based activation motif tyrosines in B cell antigen receptor signal transduction.
Topics: Antigens, CD; CD79 Antigens; Histocompatibility Antigens Class II; Humans; Lymphocyte Activation; Lymphoma, B-Cell; Mutagenesis, Insertional; Phenylalanine; Phosphorylation; Receptors, Amino Acid; Receptors, Antigen, B-Cell; Receptors, Immunologic; Recombinant Fusion Proteins; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1998 |
Twenty-four-hour L-[1-(13)C]tyrosine and L-[3,3-(2)H2]phenylalanine oral tracer studies at generous, intermediate, and low phenylalanine intakes to estimate aromatic amino acid requirements in adults.
Topics: Adolescent; Adult; Amino Acids; Carbon Isotopes; Circadian Rhythm; Deuterium; Diet; Female; Humans; Hydroxylation; Kinetics; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Tyrosine | 1998 |
An amino acid mixture deficient in phenylalanine and tyrosine reduces cerebrospinal fluid catecholamine metabolites and alcohol consumption in vervet monkeys.
Topics: Alcohol Drinking; Amino Acids; Animals; Catecholamines; Chlorocebus aethiops; Diet; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Phenylalanine; Tyrosine | 1998 |
Adsorption dynamics of L-glutamic acid copolymers at a heptane/water interface.
Topics: Adsorption; Alanine; Circular Dichroism; Glutamic Acid; Heptanes; Hydrogen-Ion Concentration; Image Processing, Computer-Assisted; Isoelectric Point; Leucine; Molecular Conformation; Phenylalanine; Polymers; Surface Properties; Surface Tension; Tyrosine | 1998 |
The advantage of phenylalanine to tyrosine ratio for the early detection of phenylketonuria.
Topics: Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Tyrosine | 1998 |
Characterization of Y122F R2 of Escherichia coli ribonucleotide reductase by time-resolved physical biochemical methods and X-ray crystallography.
Topics: Amino Acid Substitution; Apoproteins; Cold Temperature; Cross-Linking Reagents; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferric Compounds; Free Radicals; Freezing; Hydrogen-Ion Concentration; Models, Molecular; Oxygen; Phenylalanine; Ribonucleotide Reductases; Spectrophotometry; Spectroscopy, Mossbauer; Tyrosine | 1998 |
The two 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase isoenzymes from Saccharomyces cerevisiae show different kinetic modes of inhibition.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Isoenzymes; Phenylalanine; Saccharomyces cerevisiae; Tyrosine | 1998 |
A tyrosine residue essential for catalytic activity in aminopeptidase A.
Topics: Amino Acid Substitution; Aminopeptidases; Animals; Binding Sites; COS Cells; Enzyme Inhibitors; Glutamates; Glutamyl Aminopeptidase; Histidine; Imidazoles; Kinetics; Metalloendopeptidases; Mutagenesis, Site-Directed; Organophosphonates; Phenylalanine; Recombinant Proteins; Tyrosine | 1997 |
Steady state and time-resolved fluorescence study of residual structures in an unfolded form of yeast phosphoglycerate kinase.
Topics: Acrylamide; Acrylamides; Cold Temperature; Diffusion; Guanidine; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Phosphoglycerate Kinase; Protein Conformation; Protein Denaturation; Protein Folding; Saccharomyces cerevisiae; Solvents; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Viscosity | 1998 |
Circular dichroism and electron microscopy of a core Y61F mutant of the F1 gene 5 single-stranded DNA-binding protein and theoretical analysis of CD spectra of four Tyr --> Phe substitutions.
Topics: Amino Acid Substitution; Binding Sites; Circular Dichroism; DNA-Binding Proteins; DNA, Single-Stranded; DNA, Superhelical; Inovirus; Macromolecular Substances; Mutagenesis, Site-Directed; Phenylalanine; Poly A; Protein Folding; Solutions; Titrimetry; Tyrosine; Viral Proteins | 1998 |
Accurate measurement of cholecystokinin in plasma.
Topics: Adult; Animals; Antibodies; Antibody Specificity; Cholecystokinin; Cross Reactions; Female; Gastrins; Guinea Pigs; Humans; Immunization; Intestinal Mucosa; Male; Mice; Peptide Fragments; Phenylalanine; Rabbits; Radioimmunoassay; Reproducibility of Results; Sensitivity and Specificity; Swine; Tyrosine | 1998 |
Tyr254 hydroxyl group acts as a two-way switch mechanism in the coupling of heterotropic and homotropic effects in Escherichia coli glucosamine-6-phosphate deaminase.
Topics: Acetylglucosamine; Aldose-Ketose Isomerases; Allosteric Regulation; Amino Acid Substitution; Escherichia coli; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Tyrosine | 1998 |
New paramagnetic species formed at the expense of the transient tyrosyl radical in mutant protein R2 F208Y of Escherichia coli ribonucleotide reductase.
Topics: Binding Sites; Dihydroxyphenylalanine; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Models, Chemical; Mutation; Nonheme Iron Proteins; Phenylalanine; Ribonucleotide Reductases; Tyrosine | 1998 |
How the substitution of K188 of trypsin binding site by aromatic amino acids can influence the processing of beta-casein.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Binding Sites; Caseins; Hydrogen-Ion Concentration; Hydrolysis; Lysine; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Peptides; Phenylalanine; Protein Conformation; Substrate Specificity; Trypsin; Tryptophan; Tyrosine | 1998 |
pi-Stacking interactions. Alive and well in proteins.
Topics: Crystallography, X-Ray; Databases, Factual; Dimerization; Histidine; Models, Chemical; Phenylalanine; Protein Conformation; Proteins; Static Electricity; Tryptophan; Tyrosine | 1998 |
Relationships between phenylalanine hydroxylation and plasma aromatic amino acid concentrations in humans.
Topics: Adult; Amino Acids; Food; Humans; Hydroxylation; Injections, Intravenous; Insulin; Kinetics; Male; Middle Aged; Osmolar Concentration; Phenylalanine; Regression Analysis; Tyrosine | 1998 |
Phenylketonuria. The in vivo hydroxylation rate of phenylalanine into tyrosine is decreased.
Topics: Adolescent; Adult; Child; Child, Preschool; Humans; Hydroxylation; Phenylalanine; Phenylketonurias; Tyrosine | 1998 |
Active-site binding of glycosides by Thermomonospora fusca endocellulase E2.
Topics: Actinomycetales; Bacterial Proteins; Binding Sites; Calorimetry; Cellobiose; Cellulase; Glucose; Glucosides; Glycosides; Hydrogen-Ion Concentration; Hymecromone; Kinetics; Ligands; Mutagenesis, Site-Directed; Phenylalanine; Serine; Spectrometry, Fluorescence; Thermodynamics; Titrimetry; Tyrosine | 1998 |
Contribution of hydrogen bonds to the conformational stability of human lysozyme: calorimetry and X-ray analysis of six tyrosine --> phenylalanine mutants.
Topics: Calorimetry, Differential Scanning; Crystallography, X-Ray; Humans; Hydrogen Bonding; Models, Molecular; Muramidase; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein Denaturation; Protein Folding; Tyrosine | 1998 |
Loss of polymerase activity due to Tyr to Phe substitution in the YMDD motif of human immunodeficiency virus type-1 reverse transcriptase is compensated by Met to Val substitution within the same motif.
Topics: Amino Acid Substitution; Base Sequence; Deoxyribonucleotides; Dideoxynucleosides; DNA-Directed DNA Polymerase; DNA, Viral; Enzyme Activation; HIV Reverse Transcriptase; Humans; Kinetics; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleocapsid Proteins; Phenylalanine; RNA, Viral; Substrate Specificity; Templates, Genetic; Tyrosine; Valine | 1998 |
High-efficiency incorporation in vivo of tyrosine analogues with altered hydroxyl acidity in place of the catalytic tyrosine-14 of Delta 5-3-ketosteroid isomerase of Comamonas (Pseudomonas) testosteroni: effects of the modifications on isomerase kinetics.
Topics: Amino Acid Substitution; Catalysis; Electrophoresis, Polyacrylamide Gel; Fluorine Radioisotopes; Gram-Negative Aerobic Rods and Cocci; Hydrogen-Ion Concentration; Hydroxides; Kinetics; Mass Spectrometry; Phenylalanine; Steroid Isomerases; Tyrosine | 1998 |
The terminal adenosine of tRNA(Gln) mediates tRNA-dependent amino acid recognition by glutaminyl-tRNA synthetase.
Topics: Adenosine; Amino Acyl-tRNA Synthetases; Binding Sites; Enzyme Activation; Escherichia coli; Mutagenesis, Site-Directed; Phenylalanine; RNA, Transfer, Gln; Substrate Specificity; Tyrosine | 1998 |
Regulation of apoptosis by tyrosine-containing domains of IL-4R alpha: Y497 and Y713, but not the STAT6-docking tyrosines, signal protection from apoptosis.
Topics: Animals; Apoptosis; Humans; Insulin Receptor Substrate Proteins; Mice; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoproteins; Phosphoric Monoester Hydrolases; Protein Structure, Tertiary; Receptor, Insulin; Receptors, Interleukin-2; Receptors, Interleukin-4; Signal Transduction; src Homology Domains; STAT6 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1998 |
Absence of autophosphorylation site Y882 in the p185neu oncogene product correlates with a reduction of transforming potential.
Topics: Amino Acid Substitution; Animals; Binding Sites; Cell Division; Cell Transformation, Neoplastic; Epidermal Growth Factor; ErbB Receptors; Mitogens; Mutagenesis, Site-Directed; Oncogenes; Phenylalanine; Phosphorylation; Rats; Receptor, ErbB-2; Tyrosine | 1998 |
Differential scanning calorimetry study of the thermodynamic stability of some mutants of Sso7d from Sulfolobus solfataricus.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Calorimetry, Differential Scanning; DNA-Binding Proteins; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Osmolar Concentration; Phenylalanine; Protein Denaturation; Sulfolobus; Thermodynamics; Tryptophan; Tyrosine | 1998 |
Influence of tyrosine and phenylalanine limitation of cytotoxicity of chimeric TGF-alpha toxins on B16BL6 murine melanoma in vitro.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Membrane; Culture Media; Epidermal Growth Factor; Heparin; Melanoma; Mice; Phenylalanine; Proteoglycans; Recombinant Fusion Proteins; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1998 |
Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.
Topics: Amphiregulin; Animals; Arsenicals; EGF Family of Proteins; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Growth Substances; Intercellular Signaling Peptides and Proteins; Metalloendopeptidases; Mutation; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Pyrrolidines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-4; Receptors, Cell Surface; Thiocarbamates; Thiophenes; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Phenylalanine and tyrosine metabolism in phenylketonuria heterozygotes: influence of different phenylalanine hydroxylase mutations.
Topics: Heterozygote; Humans; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1998 |
The effect of phenylalanine on DOPA synthesis in PC12 cells.
Topics: Animals; Dihydroxyphenylalanine; Hydroxylation; PC12 Cells; Phenylalanine; Rats; Reproducibility of Results; Tyrosine | 1998 |
Crystal structures of two self-hydroxylating ribonucleotide reductase protein R2 mutants: structural basis for the oxygen-insertion step of hydroxylation reactions catalyzed by diiron proteins.
Topics: Alanine; Apoenzymes; Catalysis; Crystallization; Crystallography, X-Ray; Ferrous Compounds; Glutamic Acid; Hydroxylation; Iron; Models, Molecular; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Ribonucleotide Reductases; Tyrosine | 1998 |
Partial activation of the insulin receptor kinase domain by juxtamembrane autophosphorylation.
Topics: Amino Acid Sequence; Binding, Competitive; Enzyme Activation; Humans; Kinetics; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphopeptides; Phosphorylation; Protein Structure, Tertiary; Receptor, Insulin; Substrate Specificity; Tyrosine | 1998 |
Role of D1-His190 in proton-coupled electron transfer reactions in photosystem II: a chemical complementation study.
Topics: Cyanobacteria; Electron Transport; Histidine; Imidazoles; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photolysis; Photosynthetic Reaction Center Complex Proteins; Protons; Spectrophotometry; Spectroscopy, Near-Infrared; Tyrosine | 1998 |
Aberrant phenylalanine metabolism in phenylketonuria heterozygotes.
Topics: Adult; Female; Genetic Heterogeneity; Heterozygote; Humans; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 1998 |
Resistance of aryl-substituted phenylalanines to decarboxylation in the rat.
Topics: Animals; Decarboxylation; Female; Oxidation-Reduction; Phenethylamines; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Wistar; Tyrosine | 1998 |
Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Topics: Alanine; Binding Sites; Crystallography, X-Ray; Escherichia coli; Models, Molecular; Mutagenesis, Insertional; NAD; Phenylalanine; Serine; Tyrosine; UDPglucose 4-Epimerase; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose | 1998 |
Recognition of single-stranded DNA by nuclease P1: high resolution crystal structures of complexes with substrate analogs.
Topics: Catalysis; Crystallography, X-Ray; DNA, Single-Stranded; Models, Molecular; Nucleic Acid Conformation; Penicillium; Phenylalanine; Single-Strand Specific DNA and RNA Endonucleases; Substrate Specificity; Tyrosine | 1998 |
TMC-52A to D, novel cysteine proteinase inhibitors, produced by Gliocladium sp.
Topics: Cathepsin L; Cathepsins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Endopeptidases; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mitosporic Fungi; Molecular Structure; Phenylalanine; Succinates; Tyrosine | 1998 |
Investigation of the role of tyrosine-114 in the activity of human O6-alkylguanine-DNA alkyltranferase.
Topics: Alanine; Amino Acid Sequence; DNA Repair; DNA-Binding Proteins; Enzyme Activation; Glutamic Acid; Guanine; Humans; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; O(6)-Methylguanine-DNA Methyltransferase; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Threonine; Tyrosine | 1998 |
Temperature-jump and potentiometric studies on recombinant wild type and Y143F and Y254F mutants of Saccharomyces cerevisiae flavocytochrome b2: role of the driving force in intramolecular electron transfer kinetics.
Topics: Amino Acid Substitution; Electron Transport; Kinetics; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Potentiometry; Recombinant Proteins; Saccharomyces cerevisiae; Temperature; Tyrosine | 1998 |
Nutrient intake and growth of infants with phenylketonuria undergoing therapy.
Topics: Body Height; Body Weight; Diet; Dietary Proteins; Energy Intake; Female; Growth; Head; Humans; Infant; Infant Nutritional Physiological Phenomena; Male; Nutritional Status; Phenylalanine; Phenylketonurias; Tyrosine | 1998 |
Synthesis and characterization of more potent analogues of hirudin fragment 1-47 containing non-natural amino acids.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Arginine; Cattle; Circular Dichroism; Glycine; Hirudins; Humans; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Serine; Spectrometry, Fluorescence; Thrombin; Tyrosine; Valine | 1998 |
Substitution of tyrosine for phenylalanine in fibrinopeptide A results in preferential thrombin cleavage of fibrinopeptide B from fibrinogen.
Topics: Amino Acid Substitution; Animals; Catalysis; CHO Cells; Cricetinae; Fibrinogen; Fibrinopeptide A; Fibrinopeptide B; Humans; Hydrolysis; Peptide Fragments; Phenylalanine; Polymers; Recombinant Proteins; Thrombin; Time Factors; Tyrosine | 1998 |
Plasma amino acids in anorexia nervosa.
Topics: Adolescent; Amino Acids; Anorexia Nervosa; Carnitine; Chromatography, Ion Exchange; Cysteine; Female; Glycine; Humans; Insulin-Like Growth Factor I; Methionine; Phenylalanine; Reference Values; Tyrosine; Valine | 1998 |
Grb2 binding to the different isoforms of Ret tyrosine kinase.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Substitution; Animals; Binding Sites; Cell Extracts; Cloning, Molecular; COS Cells; Drosophila Proteins; Glial Cell Line-Derived Neurotrophic Factor Receptors; Glutathione Transferase; GRB2 Adaptor Protein; Intracellular Signaling Peptides and Proteins; Isoenzymes; Mice; Mutagenesis, Site-Directed; Oncogene Proteins; Phenylalanine; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; Recombinant Fusion Proteins; SH2 Domain-Containing Protein Tyrosine Phosphatases; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tyrosine | 1998 |
Demonstration that the TyrR protein and RNA polymerase complex formed at the divergent P3 promoter inhibits binding of RNA polymerase to the major promoter, P1, of the aroP gene of Escherichia coli.
Topics: Amino Acid Transport Systems; Bacterial Proteins; Base Sequence; Carrier Proteins; DNA Footprinting; DNA-Directed RNA Polymerases; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Models, Genetic; Molecular Sequence Data; Phenylalanine; Promoter Regions, Genetic; Protein Binding; Repressor Proteins; Transcription, Genetic; Tyrosine | 1998 |
Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
Topics: Amino Acid Substitution; Binding Sites; Cobamides; Crystallization; Crystallography, X-Ray; Deuterium; Enzyme Stability; Free Radicals; Kinetics; Methylmalonyl-CoA Mutase; Mutagenesis, Site-Directed; Phenylalanine; Propionibacterium; Tritium; Tyrosine | 1998 |
The post-translational modification in cytochrome c oxidase is required to establish a functional environment of the catalytic site.
Topics: Binding Sites; Catalysis; Electron Transport Complex IV; Heme; Ligands; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Protein Processing, Post-Translational; Rhodobacter sphaeroides; Spectrum Analysis, Raman; Tyrosine | 1998 |
Contribution to substrate recognition of two aromatic amino acid residues in putative transmembrane segment 10 of the yeast sugar transporters Gal2 and Hxt2.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Biological Transport; Cell Membrane; DNA Primers; Galactose; Glucose; Glucose Transport Proteins, Facilitative; Membrane Proteins; Monosaccharide Transport Proteins; Phenylalanine; Protein Conformation; Saccharomyces cerevisiae Proteins; Tyrosine | 1998 |
Vanadate-dependent FAK activation is accomplished by the sustained FAK Tyr-576/577 phosphorylation.
Topics: Amino Acid Substitution; Animals; Cell Adhesion Molecules; Cells, Cultured; Chick Embryo; CSK Tyrosine-Protein Kinase; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine; Vanadates | 1998 |
Allostery in rabbit pyruvate kinase: development of a strategy to elucidate the mechanism.
Topics: Allosteric Regulation; Animals; Binding Sites; Circular Dichroism; Energy Metabolism; Kidney; Kinetics; Lysine; Mathematical Computing; Models, Molecular; Muscle, Skeletal; Mutagenesis, Site-Directed; Phenylalanine; Proline; Protein Conformation; Protein Structure, Secondary; Pyruvate Kinase; Rabbits; Recombinant Proteins; Serine; Structure-Activity Relationship; Tyrosine; Ultracentrifugation | 1998 |
Mutation to phenylalanine of tyrosine 371 in tyrosine hydroxylase increases the affinity for phenylalanine.
Topics: Amino Acid Substitution; Animals; Binding Sites; Catalysis; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Rats; Recombinant Proteins; Tyrosine; Tyrosine 3-Monooxygenase | 1998 |
Syk- and Lyn-dependent phosphorylation of Syk on multiple tyrosines following B cell activation includes a site that negatively regulates signaling.
Topics: Amino Acid Sequence; Animals; B-Lymphocytes; Binding Sites; Catalysis; Cell Line; Chickens; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Precursors; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Molecular Sequence Data; Mutagenesis; Phenylalanine; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Syk Kinase; Trypsin; Tyrosine | 1998 |
Use of phenylalanine-to-tyrosine ratio determined by tandem mass spectrometry to improve newborn screening for phenylketonuria of early discharge specimens collected in the first 24 hours.
Topics: Blood Specimen Collection; False Positive Reactions; Fluorometry; Humans; Infant, Newborn; Mass Spectrometry; Neonatal Screening; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1998 |
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Binding Sites; Cell Transformation, Neoplastic; Female; GRB2 Adaptor Protein; Mice; Mice, Nude; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Metastasis; Oncogenes; Phenylalanine; Point Mutation; Proteins; Proto-Oncogene Proteins c-met; Recombinant Fusion Proteins; Sequence Deletion; Signal Transduction; Structure-Activity Relationship; Tyrosine | 1998 |
Metabolism of L-phenylalanine and L-tyrosine by the phototrophic bacterium Rhodobacter capsulatus.
Topics: Chromatography, High Pressure Liquid; Clinical Enzyme Tests; Ketoglutaric Acids; Phenylalanine; Rhodobacter capsulatus; Transaminases; Tyrosine | 1999 |
Pre-steady-state and steady-state kinetic studies on transcription initiation catalyzed by T7 RNA polymerase and its active-site mutants K631R and Y639F.
Topics: Amino Acid Substitution; Arginine; Binding Sites; Catalysis; DNA-Directed RNA Polymerases; Enzyme Stability; Kinetics; Lysine; Macromolecular Substances; Mutagenesis, Site-Directed; Phenylalanine; Templates, Genetic; Transcription, Genetic; Tyrosine; Viral Proteins | 1998 |
Altering the purine specificity of hypoxanthine-guanine-xanthine phosphoribosyltransferase from Tritrichomonas foetus by structure-based point mutations in the enzyme protein.
Topics: Adenine Phosphoribosyltransferase; Amino Acid Substitution; Animals; Arginine; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Enzyme Activation; Glutamic Acid; Guanine; Guanosine Monophosphate; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Purines; Ribonucleotides; Serine; Structure-Activity Relationship; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 1998 |
PhhC is an essential aminotransferase for aromatic amino acid catabolism in Pseudomonas aeruginosa.
Topics: Amino Acid Sequence; Blotting, Southern; Blotting, Western; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Mutagenesis, Insertional; Operon; Phenylalanine; Phenylalanine Hydroxylase; Pseudomonas aeruginosa; Sequence Analysis, DNA; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Transaminases; Tyrosine | 1998 |
Treatment of phenylketonuria.
Topics: Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1998 |
L-tryptophan in maternal phenylketonuria.
Topics: Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Tryptophan; Tyrosine | 1998 |
A hydrophobic cluster between transmembrane helices 5 and 6 constrains the thyrotropin-releasing hormone receptor in an inactive conformation.
Topics: Animals; Cell Membrane; Computer Simulation; COS Cells; Luciferases; Midazolam; Models, Molecular; Mutation; Phenylalanine; Plasmids; Protein Conformation; Receptors, Thyrotropin-Releasing Hormone; Transfection; Tryptophan; Tyrosine | 1998 |
Formation and fate of tyrosine. Intracellular partitioning of newly synthesized tyrosine in mammalian liver.
Topics: Animals; Biological Transport; Cell Compartmentation; Cells, Cultured; Culture Media, Serum-Free; Dexamethasone; Glucagon; Insulin; Kinetics; Liver; Male; Models, Biological; Models, Chemical; Phenylalanine; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrosine Transaminase | 1998 |
Lipid properties and the orientation of aromatic residues in OmpF, influenza M2, and alamethicin systems: molecular dynamics simulations.
Topics: Alamethicin; Computer Simulation; Influenza A virus; Lipid Bilayers; Membrane Lipids; Models, Molecular; Phenylalanine; Porins; Protein Structure, Secondary; Thermodynamics; Tryptophan; Tyrosine; Viral Matrix Proteins | 1998 |
Identification of two new hydrophobic residues on basic fibroblast growth factor important for fibroblast growth factor receptor binding.
Topics: Amino Acid Substitution; Amino Acids; Binding, Competitive; Chromatography, Liquid; Cytoplasm; Fibroblast Growth Factor 2; Humans; Inclusion Bodies; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Receptors, Fibroblast Growth Factor; Recombinant Proteins; Solubility; Solvents; Tyrosine; Valine | 1998 |
Recognition of partially-folded mitochondrial malate dehydrogenase by GroEL. Steady and time-dependent emission anisotropy measurements.
Topics: Adenosine Triphosphate; Anisotropy; Chaperonin 60; Malate Dehydrogenase; Mitochondria; ortho-Aminobenzoates; Phenylalanine; Protein Denaturation; Protein Folding; Spectrometry, Fluorescence; Time Factors; Tyrosine | 1998 |
The artificial alpha1beta1-contact mutant hemoglobin, Hb Phe-35beta, shows only small functional abnormalities.
Topics: Amino Acid Substitution; Binding Sites; Globins; Hemoglobins; Humans; Hydrogen Bonding; Kinetics; Macromolecular Substances; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxyhemoglobins; Phenylalanine; Point Mutation; Protein Conformation; Recombinant Proteins; Tyrosine | 1998 |
The differential specificity of chymotrypsin A and B is determined by amino acid 226.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Cattle; Chymotrypsin; Glycine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phenylalanine; Protein Isoforms; Rats; Recombinant Proteins; Sequence Homology, Amino Acid; Serine Endopeptidases; Substrate Specificity; Tryptophan; Tyrosine | 1999 |
Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues.
Topics: Amino Acids; Arteriosclerosis; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Isotopes; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Phenylalanine; Proteins; Reference Standards; Tyrosine | 1999 |
Simultaneous determination of plasma enrichments of 1-13C- and 15N-labelled phenylalanine and tyrosine.
Topics: Carbon Isotopes; Gas Chromatography-Mass Spectrometry; Nitrogen Isotopes; Phenylalanine; Tyrosine | 1998 |
Focal adhesion kinase-dependent apoptosis of melanoma induced by tyrosine and phenylalanine deficiency.
Topics: Animals; Apoptosis; Calcium; Cell Adhesion Molecules; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; G1 Phase; Humans; Intracellular Fluid; Melanoma; Melanoma, Experimental; Mice; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-myc; Resting Phase, Cell Cycle; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyrosine | 1999 |
Self-glucosylation of glycogenin, the initiator of glycogen biosynthesis, involves an inter-subunit reaction.
Topics: Amino Acid Substitution; Animals; Calmodulin-Binding Proteins; Catalysis; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glucose; Glucosyltransferases; Glutamine; Glutathione Transferase; Glycogen; Glycoproteins; Glycosylation; Lysine; Molecular Weight; Mutagenesis, Site-Directed; Phenylalanine; Rabbits; Recombinant Fusion Proteins; Recombinant Proteins; Tyrosine | 1999 |
Role of aromaticity of agonist switches of angiotensin II in the activation of the AT1 receptor.
Topics: Angiotensin I; Angiotensin II; Animals; COS Cells; Phenylalanine; Receptors, Angiotensin; Tyrosine | 1999 |
Vascular sources of phenylalanine, tyrosine, lysine, and methionine for casein synthesis in lactating goats.
Topics: Animals; Carbon Isotopes; Caseins; Deuterium; Female; Goats; Hydroxylation; Kinetics; Lactation; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Tyrosine | 1999 |
Defects of tyrosine289phenylalanine mutation on binding and functional properties of the human tachykinin NK2 receptor stably expressed in chinese hamster ovary cells.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Guanosine Triphosphate; Humans; Inositol 1,4,5-Trisphosphate; Neurokinin A; Phenoxybenzamine; Phenylalanine; Point Mutation; Receptors, Neurokinin-2; Signal Transduction; Substance P; Tachykinins; Transfection; Tyrosine | 1999 |
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells.
Topics: Breast Neoplasms; Endopeptidases; Humans; Hydroxamic Acids; Metalloendopeptidases; Phenylalanine; Phosphorylation; Protease Inhibitors; Receptor, ErbB-2; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
Protein metabolism in glucagonoma.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine | 1999 |
Filamentous phage replication initiator protein gpII forms a covalent complex with the 5' end of the nick it introduced.
Topics: Coliphages; DNA Replication; DNA-Binding Proteins; In Situ Nick-End Labeling; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Plasmids; Tyrosine; Viral Proteins | 1999 |
Phenylalanine and tyrosine quantification by stable isotope dilution liquid chromatography-mass spectrometry from filter paper blood spots.
Topics: Blood Specimen Collection; Chromatography, High Pressure Liquid; Humans; Mass Spectrometry; Paper; Phenylalanine; Radioisotope Dilution Technique; Tyrosine | 1999 |
The effects of a point mutation of the beta2 subunit of GABA(A) receptor on direct and modulatory actions of general anesthetics.
Topics: Amino Acid Substitution; Anesthetics, General; Animals; Chloride Channels; Dose-Response Relationship, Drug; Etomidate; GABA Modulators; gamma-Aminobutyric Acid; Hypnotics and Sedatives; Membrane Potentials; Mice; Oocytes; Pentobarbital; Phenylalanine; Point Mutation; Propofol; Receptors, GABA-A; Tyrosine; Xenopus laevis | 1999 |
Identification of residues of Escherichia coli phosphofructokinase that contribute to nucleotide binding and specificity.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acids; Arginine; Binding Sites; Cytidine Triphosphate; Escherichia coli; Guanosine Triphosphate; Inosine Triphosphate; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Phosphofructokinase-1; Substrate Specificity; Tyrosine; Uridine Triphosphate | 1999 |
Brain-derived neurotrophic factor induces phosphorylation of fibroblast growth factor receptor substrate 2.
Topics: Adaptor Proteins, Signal Transducing; Animals; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; GRB2 Adaptor Protein; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Phenylalanine; Phosphoproteins; Phosphorylation; Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Tyrosine | 1999 |
Transcriptional induction by aromatic amino acids in Saccharomyces cerevisiae.
Topics: Amino Acid Sequence; Amino Acids; Base Sequence; Carrier Proteins; Cloning, Molecular; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Fungal; Genes, Reporter; Molecular Sequence Data; Mutation; Phenylalanine; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Saccharomyces cerevisiae; Sequence Analysis, DNA; Transaminases; Transcription Factors; Tryptophan; Tyrosine | 1999 |
Sugar ring distortion in the glycosyl-enzyme intermediate of a family G/11 xylanase.
Topics: Amino Acid Substitution; Bacillus; Catalysis; Crystallography, X-Ray; Disaccharides; Endo-1,4-beta Xylanases; Gram-Positive Asporogenous Rods; Models, Molecular; Phenylalanine; Protein Conformation; Substrate Specificity; Tyrosine; Xylose; Xylosidases | 1999 |
Haloalkane dehalogenases: steady-state kinetics and halide inhibition.
Topics: Amino Acid Sequence; Binding, Competitive; Chlorides; Enzyme Inhibitors; Ethylene Chlorohydrin; Gram-Negative Aerobic Bacteria; Hydrogen-Ion Concentration; Hydrolases; Indicators and Reagents; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrophenols; Phenolsulfonphthalein; Phenylalanine; Rhodococcus; Substrate Specificity; Tryptophan; Tyrosine | 1999 |
Hysteretic enzyme adaptation to environmental pH: change in storage pH of alkaline phosphatase leads to a pH-optimum in the opposite direction to the applied change.
Topics: Alkaline Phosphatase; Animals; Cattle; Hydrogen-Ion Concentration; Intestines; Kinetics; Phenylalanine; Protein Conformation; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 1999 |
Atomic resolution structure of biotin-free Tyr43Phe streptavidin: what is in the binding site?
Topics: Binding Sites; Biotin; Crystallography, X-Ray; Hydrogen Bonding; Phenylalanine; Protein Conformation; Recombinant Proteins; Streptavidin; Tyrosine | 1999 |
Ligand-induced conformational changes in lactose repressor: a phosphorescence and ODMR study of single-tryptophan mutants.
Topics: Amino Acid Substitution; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Histidine; Isopropyl Thiogalactoside; Lac Repressors; Lactose; Ligands; Luminescent Measurements; Macromolecular Substances; Magnetic Resonance Spectroscopy; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Repressor Proteins; Tryptophan; Tyrosine | 1999 |
Phe310 in transmembrane VI of the alpha1B-adrenergic receptor is a key switch residue involved in activation and catecholamine ring aromatic bonding.
Topics: 2-Hydroxyphenethylamine; Amino Acid Sequence; Amino Acid Substitution; Animals; Catecholamines; Cattle; COS Cells; Cricetinae; Epinephrine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenethylamines; Phenylalanine; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha-1; Sequence Alignment; Structure-Activity Relationship; Tyrosine | 1999 |
Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.
Topics: Animals; Corpus Striatum; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Male; Mazindol; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Phenylalanine; Rats; Rats, Sprague-Dawley; Salicylic Acid; Serotonin; Tyrosine | 1999 |
Xenogeneic, extracorporeal liver perfusion in primates improves the ratio of branched-chain amino acids to aromatic amino acids (Fischer's ratio).
Topics: Alanine Transaminase; Amino Acids, Branched-Chain; Animals; Aspartate Aminotransferases; Bile; Female; L-Lactate Dehydrogenase; Liver; Macaca mulatta; Male; Perfusion; Phenylalanine; Time Factors; Tyrosine; Urea | 1999 |
Aromatic amino acids are utilized and protein synthesis is stimulated during amino acid infusion in the ovine fetus.
Topics: Amino Acids; Animals; Dipeptides; Drug Combinations; Electrolytes; Fetal Proteins; Fetus; Glucose; Hydroxylation; Infusions, Intravenous; Oxidation-Reduction; Parenteral Nutrition Solutions; Phenylalanine; Solutions; Tyrosine | 1999 |
Biochemical phenotype and its relationship with genotype in hyperphenylalaninemia heterozygotes.
Topics: Female; Genetic Carrier Screening; Genotype; Humans; Male; Mutation; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Reference Values; Tyrosine | 1999 |
High-throughput mass spectrometric discovery of protein post-translational modifications.
Topics: Acetylation; Amides; Amino Acid Sequence; Amino Acid Substitution; Cysteine; Escherichia coli; Image Processing, Computer-Assisted; Keratins; Lysine; Methionine; Methylation; Molecular Sequence Data; Oxidoreductases; Peptide Elongation Factor Tu; Peptide Mapping; Peroxidases; Peroxiredoxins; Phenylalanine; Protein Processing, Post-Translational; Software; Species Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 1999 |
Light-chain framework region residue Tyr71 of chimeric B72.3 antibody plays an important role in influencing the TAG72 antigen binding.
Topics: Amino Acid Sequence; Animals; Antigens; Antigens, Neoplasm; Cattle; Glycoproteins; Hydrogen Bonding; Immunoglobulin Light Chains; Immunoglobulin Variable Region; Mice; Models, Molecular; Molecular Sequence Data; Mucins; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Conformation; Recombinant Fusion Proteins; Tyrosine | 1999 |
Whole body protein kinetics using Phe and Tyr tracers: an evaluation of the accuracy of approximated flux values.
Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Insulin; Kinetics; Male; Models, Biological; Phenylalanine; Reference Values; Tyrosine | 1999 |
Measurement of phenylalanine and tyrosine in plasma by high-performance liquid chromatography using the inherent fluorescence of aromatic amino acids.
Topics: Chromatography, High Pressure Liquid; Fluorescence; Humans; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1999 |
[Perioperative plasma amino acid spectrum analysis in portal hypertensive cirrhotic patients undergoing portacaval H-graft shunt].
Topics: Adult; Amino Acids, Branched-Chain; Female; Humans; Hypertension, Portal; Intraoperative Period; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Portasystemic Shunt, Surgical; Tyrosine | 1997 |
Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes.
Topics: 3T3 Cells; Animals; Cell Line, Transformed; Fibroblasts; Gene Expression Regulation; Genes, Immediate-Early; Genes, Overlapping; Humans; Interferon-gamma; Mice; Mutagenesis; Phenylalanine; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Macrophage Colony-Stimulating Factor; Receptor, Platelet-Derived Growth Factor beta; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tyrosine | 1999 |
Oral phenylalanine loading profiles in symptomatic and asymptomatic gene carriers with dopa-responsive dystonia due to dominantly inherited GTP cyclohydrolase deficiency.
Topics: Administration, Oral; Dopamine; Dystonia; Genetic Diseases, Inborn; GTP Cyclohydrolase; Heterozygote; Humans; Phenylalanine; Tyrosine | 1999 |
Variant of dihydropteridine reductase deficiency without hyperphenylalaninaemia: effect of oral phenylalanine loading.
Topics: Administration, Oral; Biopterins; Child; Child, Preschool; Humans; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1999 |
Contribution of separate tryptophan residues to intrinsic fluorescence of actin. Analysis of 3D structure.
Topics: Actins; Cysteine; Fluorescence; Methionine; Models, Molecular; Phenylalanine; Proline; Protein Structure, Secondary; Solvents; Tryptophan; Tyrosine | 1999 |
Stages in iron storage in the ferritin of Escherichia coli (EcFtnA): analysis of Mössbauer spectra reveals a new intermediate.
Topics: Alanine; Dimerization; Escherichia coli; Ferric Compounds; Ferritins; Ferrous Compounds; Freezing; Glutamic Acid; Humans; Iron; Iron Isotopes; Mutagenesis, Site-Directed; Phenylalanine; Spectroscopy, Mossbauer; Tyrosine | 1999 |
Role of the distal phenylalanine 54 on the structure, stability, and ligand binding of Coprinus cinereus peroxidase.
Topics: Binding Sites; Coprinus; Enzyme Stability; Fungal Proteins; Glycine; Hydrogen-Ion Concentration; Imidazoles; Ligands; Mutagenesis, Site-Directed; Peroxidase; Phenylalanine; Sodium Fluoride; Spectrophotometry; Spectrum Analysis, Raman; Structure-Activity Relationship; Titrimetry; Tryptophan; Tyrosine; Valine | 1999 |
Sensitivity of electrospray-tandem mass spectrometry using the phenylalanine/tyrosine-ratio for differential diagnosis of hyperphenylalaninemia in neonates.
Topics: Diagnosis, Differential; Humans; Infant, Newborn; Mass Spectrometry; Phenylalanine; Phenylketonurias; Predictive Value of Tests; Reference Values; Sensitivity and Specificity; Tyrosine | 1999 |
Functional and structural consequences of aromatic residue substitutions within the kringle-2 domain of tissue-type plasminogen activator.
Topics: Amino Acid Substitution; Calorimetry, Differential Scanning; Fluorescence; Kringles; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein Folding; Tissue Plasminogen Activator; Tyrosine | 1999 |
The relative roles of phenylalanine and tyrosine as substrates for DOPA synthesis in PC12 cells.
Topics: Animals; Dihydroxyphenylalanine; Molecular Sequence Data; PC12 Cells; Phenylalanine; Rats; Substrate Specificity; Tyrosine; Tyrosine 3-Monooxygenase | 1999 |
Site-directed mutagenesis and molecular modeling identify a crucial amino acid in specifying the heparin affinity of FGF-1.
Topics: Amino Acid Sequence; Amino Acids; Animals; Binding Sites; Cattle; Cysteic Acid; Cysteine; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Heparin; Humans; Iodine Radioisotopes; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Recombinant Fusion Proteins; Recombinant Proteins; Serine; Tyrosine | 1999 |
Superadditive and subadditive effects of "hot spot" mutations within the interfaces of placental ribonuclease inhibitor with angiogenin and ribonuclease A.
Topics: Alanine; Animals; Arginine; Aspartic Acid; Cattle; DNA Mutational Analysis; Enzyme Inhibitors; Glycine; Humans; Kinetics; Lysine; Mutagenesis, Site-Directed; Phenylalanine; Placental Hormones; Point Mutation; Proteins; Ribonuclease, Pancreatic; Tyrosine | 1999 |
Packing of aromatic rings against tryptophan residues in proteins.
Topics: Binding Sites; Crystallography, X-Ray; Histidine; Phenylalanine; Protein Conformation; Proteins; Thermodynamics; Tryptophan; Tyrosine | 1999 |
Evaluation of phenylalanine and tyrosine metabolism in late human pregnancy.
Topics: Adult; Female; Homeostasis; Humans; Hydroxylation; Keto Acids; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnancy Trimester, Third; Proteins; Tyrosine | 1999 |
Binding affinity of N-glycans for aromatic amino acid residues: implications for novel interactions between N-glycans and proteins.
Topics: Amino Acids; Animals; Asparagine; Binding, Competitive; Cattle; Dose-Response Relationship, Drug; Lactalbumin; Phenylalanine; Polysaccharides; Protein Binding; Ribonuclease, Pancreatic; Spectrometry, Fluorescence; Sucrose; Tryptophan; Tyrosine | 1999 |
Cation-pi interactions in structural biology.
Topics: Arginine; Cations; Histidine; Lysine; Models, Chemical; Models, Molecular; Phenylalanine; Protein Conformation; Proteins; Tryptophan; Tyrosine | 1999 |
Tyrosine, phenylalanine, and disulfide contributions to the circular dichroism of proteins: circular dichroism spectra of wild-type and mutant bovine pancreatic trypsin inhibitor.
Topics: Animals; Aprotinin; Benzene Derivatives; Cattle; Circular Dichroism; Computational Biology; Crystallization; Crystallography, X-Ray; Disulfides; Models, Chemical; Phenols; Phenylalanine; Recombinant Fusion Proteins; Tyrosine | 1999 |
The importance of L-phenylalanine transport and its autocrine turnover to L-tyrosine for melanogenesis in human epidermal melanocytes.
Topics: Autocrine Communication; Biological Transport; Calcium; Cells, Cultured; Epidermal Cells; Epidermis; Female; Homeostasis; Humans; Male; Melanins; Melanocytes; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1999 |
Platelet-derived growth factor-induced activation of sphingosine kinase requires phosphorylation of the PDGF receptor tyrosine residue responsible for binding of PLCgamma.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amino Acid Substitution; Animals; Calcium; Cell Division; Cell Line; Chelating Agents; DNA; Dogs; Egtazic Acid; Enzyme Activation; Isoenzymes; Mutagenesis, Site-Directed; Phenylalanine; Phospholipase C gamma; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Platelet-Derived Growth Factor; Receptor Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Thapsigargin; Transfection; Type C Phospholipases; Tyrosine | 1999 |
Functional analyses of AmpC beta-lactamase through differential stability.
Topics: Amino Acid Substitution; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Enzyme Stability; Escherichia coli; Hot Temperature; Phenylalanine; Protein Denaturation; Solvents; Tyrosine | 1999 |
Pentoxifylline improves insulin action limiting skeletal muscle catabolism after infection.
Topics: Analysis of Variance; Animals; Culture Techniques; Escherichia coli Infections; Forelimb; Insulin; Male; Muscle Proteins; Muscle, Skeletal; Pentoxifylline; Phenylalanine; Phosphodiesterase Inhibitors; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine | 1999 |
Mechanism of repression of the aroP P2 promoter by the TyrR protein of Escherichia coli.
Topics: Amino Acid Transport Systems; Bacterial Proteins; Base Sequence; Binding Sites; Carrier Proteins; Deoxyribonuclease I; DNA Footprinting; Enzyme Repression; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Membrane Transport Proteins; Molecular Sequence Data; Phenylalanine; Potassium Permanganate; Promoter Regions, Genetic; Repressor Proteins; Transcription, Genetic; Tyrosine | 1999 |
The role of tyrosine-9 and the C-terminal helix in the catalytic mechanism of Alpha-class glutathione S-transferases.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Dinitrochlorobenzene; Ethacrynic Acid; Glutathione Transferase; Isoenzymes; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Recombinant Proteins; Substrate Specificity; Tyrosine | 1999 |
Yeast protein farnesyltransferase. pKas of peptide substrates bound as zinc thiolates.
Topics: Alkyl and Aryl Transferases; Binding Sites; Disulfides; Fluorescence Polarization; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Organometallic Compounds; Peptides; Phenylalanine; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Substrate Specificity; Sulfhydryl Compounds; Tyrosine; Zinc | 1999 |
Roles of active site aromatic residues in catalysis by ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Equilenin; Kinetics; Mutagenesis, Site-Directed; Nandrolone; Phenylalanine; Pseudomonas putida; Recombinant Proteins; Spectrometry, Fluorescence; Steroid Isomerases; Tryptophan; Tyrosine | 1999 |
Decreased serum ubiquinone-10 concentrations in phenylketonuria.
Topics: Adolescent; Adult; Antidotes; Child; Child, Preschool; Cholesterol; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Diet; Female; Humans; Infant; Male; Phenylalanine; Phenylketonurias; Reference Values; Retrospective Studies; Tyrosine; Ubiquinone | 1999 |
Sex differences in the effect of obesity on human plasma tryptophan/large neutral amino acid ratio.
Topics: Amino Acids; Body Mass Index; Female; Humans; Leucine; Male; Obesity; Phenylalanine; Sex Characteristics; Tryptophan; Tyrosine; Valine | 1999 |
The hydroxyl radical formation system in polymorphonuclear leukocytes.
Topics: Animals; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Neutrophils; Peroxidase; Phenylalanine; Swine; Tyrosine | 1999 |
Structure/function of the human glucocorticoid receptor: tyrosine 735 is important for transactivation.
Topics: Animals; Binding Sites; COS Cells; Dexamethasone; Humans; Ligands; Models, Molecular; Mutation; NF-kappa B; Phenylalanine; Protein Conformation; Receptors, Glucocorticoid; Recombinant Proteins; Structure-Activity Relationship; Transcriptional Activation; Tyrosine; Valine | 1999 |
Tryptophan H33 plays an important role in pyrimidine (6-4) pyrimidone photoproduct binding by a high-affinity antibody.
Topics: Alanine; Amino Acid Substitution; Antibody Affinity; Antibody Specificity; Chromatography, Affinity; DNA; Immunoglobulin Fragments; Immunoglobulin Variable Region; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Folding; Pyrimidine Dimers; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan; Tyrosine | 1999 |
The alpha-isoform of class II phosphoinositide 3-kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs.
Topics: 3T3 Cells; Adipocytes; Amino Acid Motifs; Amino Acid Substitution; Animals; Cell Line; Humans; Isoenzymes; Mice; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositol 3-Kinases; Receptor, IGF Type 1; Receptor, Insulin; Recombinant Fusion Proteins; Tyrosine | 1999 |
A hydrophobic patch in ecotropic murine leukemia virus envelope protein is the putative binding site for a critical tyrosine residue on the cellular receptor.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Animals; Binding Sites; Cell Line, Transformed; Friend murine leukemia virus; Glycoproteins; Humans; Membrane Glycoproteins; Methionine; Mice; Models, Molecular; Molecular Sequence Data; Moloney murine leukemia virus; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein Processing, Post-Translational; Receptors, Virus; Retroviridae Proteins, Oncogenic; Sequence Homology, Amino Acid; Tryptophan; Tyrosine; Viral Envelope Proteins | 1999 |
Analysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line.
Topics: Acute-Phase Proteins; Amino Acid Motifs; Amino Acid Substitution; Animals; Antigens, Neoplasm; Biomarkers, Tumor; Carrier Proteins; Colforsin; DNA-Binding Proteins; Genes, Immediate-Early; Genes, Reporter; Lectins, C-Type; Leptin; Metallothionein; Mice; Mutation; Nerve Growth Factor; Pancreatitis-Associated Proteins; PC12 Cells; Phenylalanine; Proteins; Rats; Receptors, Cell Surface; Receptors, Leptin; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation; Transfection; Tyrosine | 1999 |
Roles of aromatic residues in high interfacial activity of Naja naja atra phospholipase A2.
Topics: Amino Acid Sequence; Amino Acids, Cyclic; Animals; Base Sequence; Binding Sites; Elapid Venoms; Enzyme Activation; Humans; Kinetics; Liposomes; Methoxyhydroxyphenylglycol; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phospholipases A; Phospholipases A2; Phospholipid Ethers; Phospholipids; Polymers; Recombinant Proteins; Tryptophan; Tyrosine | 1999 |
Agonist activation and alpha-bungarotoxin inhibition of wild type and mutant alpha7 nicotinic acetylcholine receptors.
Topics: Acetylcholine; Action Potentials; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Mutagenesis, Site-Directed; Nicotine; Nicotinic Agonists; Phenylalanine; Rats; Receptors, Nicotinic; Structure-Activity Relationship; Tyrosine; Vasodilator Agents; Xenopus | 1999 |
Phenylalanine hydroxylation across the kidney in humans rapid communication.
Topics: Adult; Deuterium; Female; Hepatic Artery; Hepatic Veins; Humans; Hydroxylation; Kidney; Kinetics; Male; Phenylalanine; Phenylalanine Hydroxylase; Splanchnic Circulation; Tyrosine; Uremia | 1999 |
Characterization of the chronic myelomonocytic leukemia associated TEL-PDGF beta R fusion protein.
Topics: Animals; Base Sequence; COS Cells; DNA Primers; Humans; Leukemia, Myelomonocytic, Chronic; Ligands; Mutagenesis, Site-Directed; Oncogene Proteins, Fusion; Phenylalanine; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 1999 |
Identification of a hydrogen bond in the phe M197-->Tyr mutant reaction center of the photosynthetic purple bacterium Rhodobacter sphaeroides by X-ray crystallography and FTIR spectroscopy.
Topics: Crystallography, X-Ray; Hydrogen Bonding; Light-Harvesting Protein Complexes; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared; Tyrosine | 1999 |
Point mutation of a tyrosine in the linker region of Syk results in a gain of function.
Topics: Animals; Enzyme Precursors; Histamine Release; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; MAP Kinase Signaling System; Oncogene Protein v-cbl; Peptide Fragments; Phenylalanine; Phospholipase C gamma; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Retroviridae Proteins, Oncogenic; Syk Kinase; Transfection; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 2000 |
Using Raman spectroscopy to monitor the solvent-exposed and "buried" forms of flavin in p-hydroxybenzoate hydroxylase.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Amino Acid Substitution; Binding Sites; Flavin-Adenine Dinucleotide; Flavins; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Pseudomonas aeruginosa; Solvents; Spectrum Analysis, Raman; Tyrosine | 1999 |
Proteolytic fragmentation of the murine prion protein: role of Tyr-128 and His-177.
Topics: Animals; Endopeptidase K; Glycosylation; Glycosylphosphatidylinositols; Histidine; Humans; Leucine; Membrane Proteins; Mice; Mutation; Neuroblastoma; Phenylalanine; Prions; Serine Endopeptidases; Transfection; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1999 |
Effects on mood of acute phenylalanine/tyrosine depletion in healthy women.
Topics: Adult; Affect; Amino Acids; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Nutritional Physiological Phenomena; Phenylalanine; Stress, Psychological; Tryptophan; Tyrosine | 2000 |
A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation.
Topics: Cell Cycle Proteins; DNA-Binding Proteins; Enzyme Activation; Guanine Nucleotide Exchange Factors; Humans; Jurkat Cells; Mutagenesis; NFATC Transcription Factors; Nuclear Proteins; Phenylalanine; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; rac GTP-Binding Proteins; Receptors, Antigen, T-Cell; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine | 2000 |
Carvedilol inhibits reactive oxygen species generation by leukocytes and oxidative damage to amino acids.
Topics: Adult; Antioxidants; Carbazoles; Carvedilol; Humans; Monocytes; Neutrophils; Oxidation-Reduction; Phenylalanine; Propanolamines; Reactive Oxygen Species; Tyrosine | 2000 |
The use of phenylalanine to detect hydroxyl radical production in vivo: a cautionary note.
Topics: Animals; Cats; Chromatography, High Pressure Liquid; False Positive Reactions; Hydroxyl Radical; Phenylalanine; Tyrosine | 1999 |
Replacing two conserved tyrosines of the EphB2 receptor with glutamic acid prevents binding of SH2 domains without abrogating kinase activity and biological responses.
Topics: 3T3 Cells; Actins; Amino Acid Substitution; Animals; Cell Size; Conserved Sequence; COS Cells; Enzyme Activation; Glutamic Acid; Humans; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; Mutagenesis; Phenylalanine; Phosphorylation; Protein Binding; Receptor Protein-Tyrosine Kinases; Receptor, EphB2; src Homology Domains; src-Family Kinases; Tyrosine | 2000 |
Origin of the anomalous Fe-CO stretching mode in the CO complex of Ascaris hemoglobin.
Topics: Animals; Ascaris suum; Carbon Monoxide; Hemoglobins; Iron; Oxidoreductases; Phenylalanine; Protein Conformation; Spectrum Analysis, Raman; Tyrosine | 2000 |
The kidney is an important site for in vivo phenylalanine-to-tyrosine conversion in adult humans: A metabolic role of the kidney.
Topics: Adult; Female; Humans; Hydroxylation; Kidney; Male; Phenylalanine; Phenylalanine Hydroxylase; Proteins; Renal Circulation; Splanchnic Circulation; Tyrosine | 2000 |
Three aromatic amino acid residues critical for galactose transport in yeast Gal2 transporter.
Topics: Amino Acids; Biological Transport; Conserved Sequence; Galactose; Glucose; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Microscopy, Fluorescence; Monosaccharide Transport Proteins; Mutagenesis; Phenylalanine; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tyrosine | 2000 |
Tyrosine requirements in children with classical PKU determined by indicator amino acid oxidation.
Topics: Breath Tests; Carbon Dioxide; Carbon Isotopes; Child; Diet; Female; Humans; Hydroxylation; Lysine; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Tyrosine | 2000 |
The influence of ATP on the binding of aromatic amino acids to the ligand response domain of the tyrosine repressor of Haemophilus influenzae.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Circular Dichroism; Conserved Sequence; Escherichia coli Proteins; Haemophilus influenzae; Ligands; Phenylalanine; Protein Binding; Protein Structure, Secondary; Repressor Proteins; Spectrometry, Fluorescence; Structure-Activity Relationship; Thermodynamics; Tryptophan; Tyrosine | 2000 |
Tyrosine phosphorylation of myelin P(0) and its implication in signal transduction.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Brain; Cell Line; Cloning, Molecular; Consensus Sequence; Humans; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Myelin P0 Protein; Neurilemmoma; Phenylalanine; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Sequence Alignment; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Identification of the sites of hydroxyl radical reaction with peptides by hydrogen/deuterium exchange: prevalence of reactions with the side chains.
Topics: Deuterium; Dithiothreitol; DNA Footprinting; Enkephalin, Leucine-2-Alanine; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron; Leucine; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tyrosine | 2000 |
Mutational analysis of adeno-associated virus type 2 Rep68 protein endonuclease activity on partially single-stranded substrates.
Topics: Base Sequence; Dependovirus; DNA Helicases; DNA-Binding Proteins; DNA, Single-Stranded; DNA, Viral; Endonucleases; Gene Expression; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Fusion Proteins; Substrate Specificity; Tyrosine; Viral Proteins | 2000 |
Effects of aromatic residues at the ends of transmembrane alpha-helices on helix interactions with lipid bilayers.
Topics: Cholesterol; Golgi Apparatus; Hydrocarbons, Aromatic; Kinetics; Lipid Bilayers; Membrane Lipids; Membrane Proteins; Models, Biological; Phenylalanine; Phosphatidic Acids; Phosphatidylcholines; Phospholipids; Protein Binding; Spectrometry, Fluorescence; Tyrosine | 2000 |
Functional inactivation of the nociceptin receptor by alanine substitution of glutamine 286 at the C terminus of transmembrane segment VI: evidence from a site-directed mutagenesis study of the ORL1 receptor transmembrane-binding domain.
Topics: Alanine; Amino Acid Substitution; Animals; Asparagine; CHO Cells; Cricetinae; Glutamine; Humans; Membrane Proteins; Mutagenesis, Site-Directed; Nociceptin Receptor; Phenylalanine; Protein Conformation; Receptors, Opioid; Signal Transduction; Tryptophan; Tyrosine | 2000 |
Using entropies of reaction to predict changes in protein stability: tyrosine-67-phenylalanine variants of rat cytochrome c and yeast Iso-1 cytochromes c.
Topics: Algorithms; Amino Acid Substitution; Animals; Crystallography, X-Ray; Cytochrome c Group; Electrochemistry; Entropy; Isoenzymes; Oxidation-Reduction; Phenylalanine; Proteins; Rats; Thermodynamics; Tyrosine; Yeasts | 1999 |
Cultivation of immortalized human hepatocytes HepZ on macroporous CultiSpher G microcarriers.
Topics: Amino Acids, Branched-Chain; Anesthetics, Local; Bioreactors; Biotransformation; Cell Culture Techniques; Cell Division; Cell Line, Transformed; Cold Temperature; Culture Media; Humans; L-Lactate Dehydrogenase; Lidocaine; Liver; Liver, Artificial; Microscopy, Electron; Microscopy, Electron, Scanning; Microspheres; Oxygen Consumption; Phenylalanine; Tyrosine | 2000 |
Homology modeling, molecular dynamics simulations, and analysis of CYP119, a P450 enzyme from extreme acidothermophilic archaeon Sulfolobus solfataricus.
Topics: Amino Acid Sequence; Archaeal Proteins; Computational Biology; Computer Simulation; Cytochrome P-450 Enzyme System; Enzyme Stability; Glutamine; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Oxygenases; Phenylalanine; Proline; Salts; Sequence Homology, Amino Acid; Sulfolobus; Surface Properties; Thermodynamics; Tryptophan; Tyrosine; Water | 2000 |
Role of matrix protein in the type D retrovirus replication cycle: importance of the arginine residue at position 55.
Topics: Amino Acid Substitution; Animals; Arginine; Betaretrovirus; Capsid; Cell Line; COS Cells; Humans; Intracellular Fluid; Mutagenesis, Site-Directed; Phenotype; Phenylalanine; Proviruses; Transfection; Tumor Cells, Cultured; Tyrosine; Viral Matrix Proteins; Virus Replication | 2000 |
Production of tyrosine and other aromatic compounds from phenylalanine by rumen microorganisms.
Topics: Amino Acids; Animals; Chromatography, High Pressure Liquid; Goats; Phenylalanine; Rumen; Tyrosine | 1999 |
Expression of tryptophan decarboxylase and tyrosine decarboxylase genes in tobacco results in altered biochemical and physiological phenotypes.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aromatic-L-Amino-Acid Decarboxylases; Chlorogenic Acid; Gene Expression; Genes, Plant; Nicotiana; Nicotine; Phenotype; Phenylalanine; Phenylalanine Ammonia-Lyase; Plants, Genetically Modified; Plants, Toxic; Substrate Specificity; Temperature; Tryptophan; Tyrosine; Tyrosine Decarboxylase | 2000 |
The choline binding site of phospholipase C (Bacillus cereus): insights into substrate specificity.
Topics: Amino Acid Substitution; Bacillus cereus; Binding Sites; Catalysis; Choline; Glutamic Acid; Hydrolysis; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylcholines; Phosphatidylethanolamines; Phosphatidylserines; Recombinant Proteins; Substrate Specificity; Type C Phospholipases; Tyrosine | 2000 |
Hydrophobic residues Phe751 and Leu753 are essential for STAT5 transcriptional activity.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; COS Cells; DNA; DNA-Binding Proteins; Fungal Proteins; Leucine; Mice; Milk Proteins; Phenylalanine; Phosphorylation; Recombinant Fusion Proteins; Saccharomyces cerevisiae Proteins; Sequence Deletion; Sequence Homology, Amino Acid; STAT5 Transcription Factor; Trans-Activators; Transcription Factors; Transcription, Genetic; Tyrosine | 2000 |
The catalytic Tyr-9 of glutathione S-transferase A1-1 controls the dynamics of the C terminus.
Topics: 4-Chloro-7-nitrobenzofurazan; Amino Acid Substitution; Animals; Binding Sites; Calorimetry; Catalytic Domain; Glutathione; Glutathione Transferase; Humans; Hydrogen Bonding; Isoenzymes; Kinetics; Models, Molecular; Phenylalanine; Protein Conformation; Rats; Serine; Thermodynamics; Tyrosine | 2000 |
Interaction between the critical aromatic amino acid residues Tyr(352) and Phe(504) in the yeast Gal2 transporter.
Topics: Biological Transport; Galactose; Monosaccharide Transport Proteins; Mutagenesis; Phenylalanine; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tyrosine | 2000 |
Intracellular targeting and retention of the glucose transporter GLUT4 by the perinuclear storage compartment involves distinct carboxyl-tail motifs.
Topics: 3T3 Cells; Alanine; Amino Acid Motifs; Animals; Carboxylic Acids; Cell Compartmentation; Cell Membrane; Dipeptides; Endosomes; Enzyme Inhibitors; Genistein; Glucose Transporter Type 4; Golgi Apparatus; Insulin; Intracellular Membranes; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Peptide Fragments; Peptides; Phenylalanine; Protein-Tyrosine Kinases; rab GTP-Binding Proteins; rab7 GTP-Binding Proteins; Tyrosine | 2000 |
Effect of a tyrosine 155 to phenylalanine mutation of protein kinase cdelta on the proliferative and tumorigenic properties of NIH 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Base Sequence; Biological Transport; Cell Line; Cell Transformation, Neoplastic; DNA; Fibroblasts; Humans; Isoenzymes; Mice; Mutagenesis, Site-Directed; Phenylalanine; Protein Kinase C; Protein Kinase C-delta; Subcellular Fractions; Tetradecanoylphorbol Acetate; Tyrosine | 2000 |
Molecular recognition of amino acids by RNA aptamers: the evolution into an L-tyrosine binder of a dopamine-binding RNA motif.
Topics: Base Sequence; Binding Sites; Chromatography, Affinity; Cloning, Molecular; Directed Molecular Evolution; Dopamine; Ligands; Molecular Probe Techniques; Nucleic Acid Conformation; Oligoribonucleotides; Phenylalanine; RNA; Substrate Specificity; Thermodynamics; Tryptophan; Tyrosine | 2000 |
Tyrosine 62 of the gamma-aminobutyric acid type A receptor beta 2 subunit is an important determinant of high affinity agonist binding.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Line; GABA-A Receptor Agonists; Humans; Ion Channel Gating; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Rats; Receptors, GABA-A; Sequence Homology, Amino Acid; Tyrosine; Xenopus laevis | 2000 |
Molecular determinants of differential ligand sensitivities of insect ecdysteroid receptors.
Topics: Aedes; Amino Acid Sequence; Animals; Cell Line; Chromosome Mapping; DNA; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Ecdysone; Ecdysterone; Ligands; Molecular Sequence Data; Phenylalanine; Receptors, Steroid; Sequence Homology, Amino Acid; Transcription Factors; Transcriptional Activation; Tyrosine | 2000 |
Recruitment of a double bond isomerase to serve as a reductive dehalogenase during biodegradation of pentachlorophenol.
Topics: Amino Acid Sequence; Bacterial Proteins; Biodegradation, Environmental; cis-trans-Isomerases; Evolution, Molecular; Glutathione; Glutathione Transferase; Hydrolases; Isomerases; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Pentachlorophenol; Phenylalanine; Pseudomonas; Sequence Alignment; Sphingomonas; Tyrosine | 2000 |
Tryptophan-heme pi-electrostatic interactions in cytochrome f of oxygenic photosynthesis.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Chlamydomonas reinhardtii; Chloroplasts; Cyanobacteria; Cytochromes; Cytochromes f; Heme; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photosynthesis; Static Electricity; Tryptophan; Tyrosine | 2000 |
Phosphorylation of tyrosine residues in the kinase domain and juxtamembrane region regulates the biological and catalytic activities of Eph receptors.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Catalysis; Cell Membrane; Conserved Sequence; Ephrin-B1; Kinetics; Membrane Proteins; Molecular Sequence Data; Mutation; Neurites; Neurons; Phenylalanine; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptor, EphB2; Signal Transduction; Tyrosine | 2000 |
13C and (15)N kinetic isotope effects on the reaction of aspartate aminotransferase and the tyrosine-225 to phenylalanine mutant.
Topics: Amino Acid Substitution; Aspartate Aminotransferases; Carbon Isotopes; Nitrogen Isotopes; Phenylalanine; Tyrosine | 2000 |
Natural electrophoresis of norepinephrine and ascorbic acid.
Topics: Ascorbic Acid; Binding, Competitive; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Capillary; Epinephrine; Glucose; Histamine; Hydrogen-Ion Concentration; Models, Biological; Norepinephrine; Phenylalanine; Phosphorylation; Serotonin; Static Electricity; Tyrosine | 2000 |
"Hypotyrosinemia" in phenylketonuria.
Topics: Adolescent; Adult; Analysis of Variance; Child; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Review Literature as Topic; Severity of Illness Index; Tyrosine | 2000 |
Chemically prepared hevein domains: effect of C-terminal truncation and the mutagenesis of aromatic residues on the affinity for chitin.
Topics: Amino Acid Substitution; Antimicrobial Cationic Peptides; Chitin; Lectins; Magnoliopsida; Models, Molecular; Nicotiana; Peptide Fragments; Phenylalanine; Plant Lectins; Plant Proteins; Plants, Toxic; Protein Binding; Protein Structure, Tertiary; Sequence Deletion; Sequence Homology, Amino Acid; Structure-Activity Relationship; Tryptophan; Tyrosine | 2000 |
The Grb2 binding site is required for the induction of chronic myeloid leukemia-like disease in mice by the Bcr/Abl tyrosine kinase.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Binding Sites; Bone Marrow Transplantation; Fusion Proteins, bcr-abl; GRB2 Adaptor Protein; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mutation; Neoplasm Transplantation; Phenylalanine; Proteins; Structure-Activity Relationship; Transfection; Tyrosine | 2000 |
Functional comparison of the NAD binding cleft of ADP-ribosylating toxins.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cholera Toxin; Diphtheria Toxin; Hydrolysis; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NAD; Phenylalanine; Poly(ADP-ribose) Polymerases; Protein Conformation; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tyrosine | 2000 |
Derangement of the dopaminergic system in phenylketonuria: study of the event-related potential (P300).
Topics: Adolescent; Adult; Child; Dopamine; Event-Related Potentials, P300; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 2000 |
Comments on identification of a hydrogen bond in the phe-M197-->Tyr mutant reaction center of the photosynthetic purple bacterium Rhodobacter sphaeroides by x-ray crystallography and FTIR spectroscopy (FEBS 23044).
Topics: Crystallography, X-Ray; Hydrogen Bonding; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2000 |
Kinetics and crystal structure of the wild-type and the engineered Y101F mutant of Herpes simplex virus type 1 thymidine kinase interacting with (North)-methanocarba-thymidine.
Topics: Amino Acid Substitution; Binding, Competitive; Bridged Bicyclo Compounds; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Herpesvirus 1, Human; Humans; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein Conformation; Thymidine; Thymidine Kinase; Tyrosine | 2000 |
Mutation of tyrosine 318 (Y318F) in the delta-opioid receptor attenuates tyrosine phosphorylation, agonist-dependent receptor internalization, and mitogen-activated protein kinase activation.
Topics: Amino Acid Sequence; Amino Acid Substitution; Analgesics; Animals; Cell Line; CHO Cells; Conserved Sequence; Cricetinae; Enkephalin, Leucine; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Radioligand Assay; Receptors, Opioid, delta; Recombinant Proteins; Transfection; Tritium; Tyrosine | 2000 |
Mechanism of the phenylpyruvate tautomerase activity of macrophage migration inhibitory factor: properties of the P1G, P1A, Y95F, and N97A mutants.
Topics: Catalytic Domain; Cell Migration Inhibition; Intramolecular Oxidoreductases; Kinetics; Macrophage Migration-Inhibitory Factors; Models, Chemical; Models, Molecular; Mutation; Phenylalanine; Proline; Recombinant Proteins; Tyrosine | 2000 |
Metabolism of tryptophan in the liver: interference with decarboxylation of other aromatic amino acids.
Topics: Amino Acids; Animals; Aromatic-L-Amino-Acid Decarboxylases; Dihydroxyphenylalanine; In Vitro Techniques; Liver; Male; Phenylalanine; Rats; Rats, Wistar; Tryptophan; Tyrosine | 2000 |
Mutation of aromatic amino acid residues located at the amino- and carboxy-termini of Escherichia coli heat-stable enterotoxin Ip reduces the efficiency of the toxin to cross the outer membrane.
Topics: Amino Acid Substitution; Bacterial Toxins; Cell Membrane; Enterotoxins; Escherichia coli; Escherichia coli Proteins; Mutagenesis, Site-Directed; Phenylalanine; Tyrosine | 2000 |
Aspartame loading test in PKU heterozygous individuals bearing severe and moderate mutations.
Topics: Aspartame; DNA; DNA Mutational Analysis; Heterozygote; Humans; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine | 2000 |
Two amino acids in the sixth transmembrane segment of the mouse gastrin-releasing peptide receptor are important for receptor activation.
Topics: 3T3 Cells; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding, Competitive; Bombesin; Gastrin-Releasing Peptide; Iodine Radioisotopes; Ligands; Mice; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Point Mutation; Radioligand Assay; Tyrosine | 2000 |
Phosphorylation of protein kinase Cdelta on distinct tyrosine residues regulates specific cellular functions.
Topics: Animals; Cell Division; Cloning, Molecular; Enzyme Inhibitors; Genes, Dominant; Glutamate-Ammonia Ligase; Green Fluorescent Proteins; Immunoblotting; Isoenzymes; Luminescent Proteins; Mice; Microscopy, Confocal; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Protein Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Pyrazoles; Pyrimidines; Recombinant Fusion Proteins; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tyrosine | 2000 |
c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines.
Topics: Animals; Binding Sites; Catalytic Domain; DNA, Complementary; Dose-Response Relationship, Drug; Kinetics; Mice; Models, Biological; Mutation; Peptides; Phenylalanine; Phosphorylation; Point Mutation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; src Homology Domains; Time Factors; Tyrosine | 2000 |
Nitration and hydroxylation of aromatic amino acid and guanine by the air pollutant peroxyacetyl nitrate.
Topics: Air Pollutants; Amino Acids, Cyclic; Chromatography, High Pressure Liquid; Guanine; HL-60 Cells; Humans; Hydroxylation; Mass Spectrometry; Nitrates; Nitrogen; Oxidants; Peracetic Acid; Phenylalanine; Tryptophan; Tyrosine | 2000 |
Cytoprotective antioxidant function of tyrosine and tryptophan residues in transmembrane proteins.
Topics: 3T3 Cells; Amino Acids; Animals; Antioxidants; Brain; Cell Death; Cell Membrane; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Relationship, Drug; Humans; Linoleic Acid; Lipid Metabolism; Lipid Peroxidation; Membrane Proteins; Mice; Neurons; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenylalanine; Presenilin-1; Tryptophan; Tumor Cells, Cultured; Tyrosine | 2000 |
Mutation of the SHP-2 binding site in growth hormone (GH) receptor prolongs GH-promoted tyrosyl phosphorylation of GH receptor, JAK2, and STAT5B.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Binding Sites; DNA-Binding Proteins; Human Growth Hormone; Humans; Janus Kinase 2; Kinetics; Mice; Milk Proteins; Mutagenesis, Site-Directed; Phenylalanine; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Somatotropin; Recombinant Proteins; Signal Transduction; src Homology Domains; STAT5 Transcription Factor; Trans-Activators; Tyrosine | 2000 |
The enamel protein amelogenin binds to the N-acetyl-D-glucosamine-mimicking peptide motif of cytokeratins.
Topics: Acetylglucosamine; Amelogenin; Amino Acid Motifs; Animals; Binding Sites; Binding, Competitive; Dental Enamel Proteins; Dose-Response Relationship, Drug; Genetic Linkage; Hemagglutinins; Humans; Keratins; Kinetics; Mice; Models, Chemical; Peptides; Phenylalanine; Proline; Protein Binding; Serine; Time Factors; Tyrosine; X Chromosome | 2000 |
Conversion of methylamine dehydrogenase to a long-chain amine dehydrogenase by mutagenesis of a single residue.
Topics: Alanine; Amino Acid Substitution; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Phenylalanine; Substrate Specificity; Tyrosine | 2000 |
Hydrophobic interactions in the hinge domain of DNA polymerase beta are important but not sufficient for maintaining fidelity of DNA synthesis.
Topics: Amino Acid Substitution; Animals; Base Sequence; Catalysis; DNA Mutational Analysis; DNA Polymerase beta; DNA Primers; DNA Replication; Frameshift Mutation; Kinetics; Leucine; Molecular Sequence Data; Phenylalanine; Protein Structure, Tertiary; Rats; Sequence Deletion; Simplexvirus; Thymidine Kinase; Tryptophan; Tyrosine; Viral Proteins | 2000 |
Amphetamine increases glutamate efflux in the rat ventral tegmental area by a mechanism involving glutamate transporters and reactive oxygen species.
Topics: Amino Acid Transport System X-AG; Amphetamine; Animals; ATP-Binding Cassette Transporters; Behavior, Animal; Calcium; Central Nervous System Stimulants; Cyclic N-Oxides; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Phenylalanine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine; Ventral Tegmental Area | 2000 |
Ingestion of protein hydrolysate and amino acid-carbohydrate mixtures increases postexercise plasma insulin responses in men.
Topics: Adult; Amino Acids; Beverages; Bicycling; Blood Glucose; Dietary Carbohydrates; Dietary Proteins; Exercise; Humans; Insulin; Kinetics; Leucine; Male; Phenylalanine; Protein Hydrolysates; Regression Analysis; Triticum; Tyrosine | 2000 |
The active-site residue tyr-175 in human glyoxalase II contributes to binding of glutathione derivatives.
Topics: Binding Sites; Catalysis; Glutathione; Humans; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Spectrometry, Fluorescence; Thiolester Hydrolases; Tyrosine | 2000 |
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
Topics: Amino Acid Substitution; Antigens, CD; Antigens, Surface; Binding Sites; Cell Line; Cytoplasm; Desmosomes; Enzyme Inhibitors; Humans; Integrin alpha6; Integrin alpha6beta4; Integrin beta4; Integrins; Phenylalanine; Phosphopeptides; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Signal Transduction; src Homology Domains; Transfection; Tyrosine; Vanadates | 2001 |
Regulation of beta 1 integrin-mediated adhesion by T cell receptor signaling involves ZAP-70 but differs from signaling events that regulate transcriptional activity.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Carrier Proteins; Cell Adhesion; DNA-Binding Proteins; Enzyme Activation; Fibronectins; Humans; Integrin beta1; Jurkat Cells; Luciferases; Lymphocyte Activation; Membrane Proteins; NFATC Transcription Factors; Nuclear Proteins; Phenylalanine; Phosphoproteins; Point Mutation; Protein-Tyrosine Kinases; Receptor-CD3 Complex, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Transcription Factors; Transcriptional Activation; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 2000 |
Coupling of hydrogen bonding to chromophore conformation and function in photoactive yellow protein.
Topics: Ammonium Chloride; Ammonium Sulfate; Bacterial Proteins; Crystallography, X-Ray; Hydrogen Bonding; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenylalanine; Photolysis; Photoreceptors, Microbial; Pigments, Biological; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Threonine; Tyrosine; Valine | 2000 |
Phage phi 29 DNA polymerase residues involved in the proper stabilisation of the primer-terminus at the 3'-5' exonuclease active site.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacillus Phages; Binding Sites; Catalysis; Conserved Sequence; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Exodeoxyribonucleases; Histidine; Molecular Sequence Data; Multienzyme Complexes; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Sequence Alignment; Structure-Activity Relationship; Tyrosine | 2000 |
Structural requirements for the specific recognition of an m7G mRNA cap.
Topics: Amino Acid Substitution; Circular Dichroism; Eukaryotic Initiation Factor-4E; Flavins; Glutamic Acid; Guanosine; Hydrogen Bonding; Mutagenesis, Site-Directed; Peptide Initiation Factors; Phenylalanine; RNA Caps; RNA, Messenger; Spectrometry, Fluorescence; Static Electricity; Tryptophan; Tyrosine; Vaccinia virus; Viral Proteins | 2000 |
Inhibition of B16BL6 melanoma invasion by tyrosine and phenylalanine deprivation is associated with decreased secretion of plasminogen activators and increased plasminogen activator inhibitors.
Topics: Animals; Cell Adhesion; Culture Media, Conditioned; Melanoma; Mice; Neoplasm Invasiveness; Phenylalanine; Plasminogen Activators; Plasminogen Inactivators; Tissue Plasminogen Activator; Tumor Cells, Cultured; Tyrosine; Urokinase-Type Plasminogen Activator | 1999 |
Application of genomics and proteomics for identification of bacterial gene products as potential vaccine candidates.
Topics: Antibodies, Bacterial; Antibodies, Monoclonal; Antigens, Bacterial; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Vaccines; Codon; Computational Biology; Databases as Topic; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; GC Rich Sequence; Genome, Bacterial; Haemophilus influenzae; Haemophilus Vaccines; Helicobacter pylori; Open Reading Frames; Peptide Mapping; Phenylalanine; Proteome; Tyrosine | 2000 |
Parallel bioassay of 39 tachykinins on 11 smooth muscle preparations. Structure and receptor selectivity/affinity relationship.
Topics: Animals; Biological Assay; Guinea Pigs; Isoleucine; Male; Mice; Muscle, Smooth; Phenylalanine; Proline; Protein Binding; Rabbits; Rats; Rats, Wistar; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Tachykinin; Tachykinins; Tyrosine | 2000 |
Production and immunohistochemical application of antiserum against Tyr-D-Ala-Phe, a N-terminal tripeptide common to dermorphin/deltorphin family.
Topics: Alanine; Animals; Chromatography, Affinity; Immune Sera; Immunoglobulin G; Immunohistochemistry; Magnetic Resonance Spectroscopy; Oligopeptides; Opioid Peptides; Peptide Biosynthesis; Peptides; Phenylalanine; Polylysine; Protein Binding; Rabbits; Ranidae; Skin; Tyrosine | 2000 |
Kinetic alteration of a human dihydrodiol/3alpha-hydroxysteroid dehydrogenase isoenzyme, AKR1C4, by replacement of histidine-216 with tyrosine or phenylalanine.
Topics: 3-Hydroxysteroid Dehydrogenases; Amino Acid Substitution; Bile Acids and Salts; Binding Sites; Binding, Competitive; Coenzymes; Enzyme Activation; Histidine; Humans; Isoenzymes; Kinetics; Mutation; Phenylalanine; Thermodynamics; Tyrosine | 2000 |
Phenylalanine supplementation improves the phenylalanine profile in tyrosinaemia.
Topics: Child; Child, Preschool; Dietary Supplements; Humans; Infant; Phenylalanine; Treatment Outcome; Tyrosine; Tyrosinemias | 2000 |
Cation-pi effects in the complexation of Na+ and K+ with Phe, Tyr, and Trp in the gas phase.
Topics: Cations, Monovalent; Kinetics; Mass Spectrometry; Phenylalanine; Potassium; Sodium; Static Electricity; Tryptophan; Tyrosine | 2000 |
Use of the phenylalanine:tyrosine ratio to test newborns for phenylketonuria in a large public health screening programme.
Topics: California; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Laboratories; Neonatal Screening; Phenylalanine; Phenylketonurias; Pilot Projects; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2000 |
Outer sphere mutations perturb metal reactivity in manganese superoxide dismutase.
Topics: Binding Sites; Catalysis; Circular Dichroism; Computer Simulation; Conserved Sequence; Enzyme Activation; Escherichia coli; Glutamine; Histidine; Manganese; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Spectrophotometry, Ultraviolet; Superoxide Dismutase; Tyrosine | 2001 |
Role of the conserved acidic residue Asp21 in the structure of phosphatidylinositol 3-kinase Src homology 3 domain: circular dichroism and nuclear magnetic resonance studies.
Topics: Amino Acid Substitution; Asparagine; Aspartic Acid; Circular Dichroism; Conserved Sequence; Histidine; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oligopeptides; Phenylalanine; Phosphatidylinositol 3-Kinases; Protein Conformation; src Homology Domains; Tyrosine | 2001 |
Conformational restriction of the Tyr53 side-chain in the decapeptide HE.
Topics: Amino Acid Sequence; Animals; Antigen-Presenting Cells; B-Lymphocytes; Chickens; Major Histocompatibility Complex; Mice; Models, Chemical; Molecular Sequence Data; Muramidase; Peptide Biosynthesis; Peptides; Phenylalanine; Protein Binding; Protein Conformation; Receptors, Antigen, T-Cell; Temperature; Tyrosine | 2000 |
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.
Topics: Alanine; Anti-HIV Agents; Aspartic Acid; Cell Line; Deoxyguanine Nucleotides; Dideoxynucleotides; DNA-Directed DNA Polymerase; Glutamic Acid; Glutamine; HIV Reverse Transcriptase; HIV-1; Humans; Lysine; Mutagenesis, Site-Directed; Nucleosides; Phenylalanine; Recombination, Genetic; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Spiro Compounds; Thymidine; Tyrosine; Uridine | 2001 |
Detection of hydroxyl radicals by D-phenylalanine hydroxylation: a specific assay for hydroxyl radical generation in biological systems.
Topics: Cell Survival; Chromatography, High Pressure Liquid; Free Radicals; Humans; Hydroxyl Radical; Hydroxylation; Neutrophils; Phenylalanine; Tyrosine | 2001 |
Role of tyrosine 114 of L-methionine gamma-lyase from Pseudomonas putida.
Topics: Carbon-Sulfur Lyases; Catalysis; Deamination; Deuterium Oxide; Hydrogen; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Phenylalanine; Pseudomonas putida; Tyrosine | 2000 |
Non-discriminatory incorporation of L-phenylalanine and L-tyrosine into cinnamoyl part of mulberroside A, a stilbene di-glucoside, in Morus alba cell cultures.
Topics: Carbon Isotopes; Cells, Cultured; Disaccharides; Molecular Structure; Phenylalanine; Rosales; Stilbenes; Tyrosine | 2000 |
The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation.
Topics: Adult; Aged; Diet, Reducing; Female; Glucose Tolerance Test; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Male; Middle Aged; Obesity; Phenylalanine; Proteins; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tyrosine; Weight Loss | 2001 |
Plasma free amino acid concentrations in healthy Guatemalan adults and in patients with classic dengue.
Topics: Adult; Amino Acids; Case-Control Studies; Dengue; Female; Glycine; Guatemala; Humans; Male; Phenylalanine; Socioeconomic Factors; Sweden; Tyrosine; Valine | 2001 |
Decreased tissue plasminogen activator and increased plasminogen activator inhibitors and increased activator protein-1 and specific promoter 1 are associated with inhibition of invasion in human A375 melanoma deprived of tyrosine and phenylalanine.
Topics: Cell Adhesion; Culture Media, Conditioned; Fibroblasts; Humans; Infant; Melanoma; Neoplasm Invasiveness; Phenylalanine; Plasminogen Activators; Plasminogen Inactivators; Skin; Sp1 Transcription Factor; Tissue Plasminogen Activator; Transcription Factor AP-1; Tumor Cells, Cultured; Tyrosine; Urokinase-Type Plasminogen Activator | 2001 |
Effect of storage on phenylalanine and tyrosine measurements in whole-blood samples.
Topics: Adolescent; Blood Specimen Collection; Child; Child, Preschool; Humans; Infant; Phenylalanine; Proteinuria; Time Factors; Tyrosine | 2001 |
Structural plasticity of an invariant hydrophobic triad in the switch regions of Rab GTPases is a determinant of effector recognition.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Base Sequence; Crystallography, X-Ray; Epitopes; Escherichia coli; Models, Molecular; Molecular Sequence Data; Nerve Tissue Proteins; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; rab GTP-Binding Proteins; rab3A GTP-Binding Protein; rab5 GTP-Binding Proteins; Rabphilin-3A; Tryptophan; Tyrosine; Vesicular Transport Proteins | 2001 |
Tyrosine sulfation of glycoprotein I(b)alpha. Role of electrostatic interactions in von Willebrand factor binding.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cell Adhesion; Cell Line; Crotalid Venoms; Glutamic Acid; Hemagglutinins; Humans; Kinetics; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Platelet Glycoprotein GPIb-IX Complex; Protein Structure, Secondary; Recombinant Proteins; Ristocetin; Stress, Mechanical; Transfection; Tyrosine; von Willebrand Factor | 2001 |
X-ray structure analyses of photosynthetic reaction center variants from Rhodobacter sphaeroides: structural changes induced by point mutations at position L209 modulate electron and proton transfer.
Topics: Amino Acid Substitution; Binding Sites; Computer Simulation; Crystallography, X-Ray; Electron Transport; Energy Transfer; Genetic Variation; Glutamic Acid; Models, Molecular; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Point Mutation; Proline; Protons; Quinones; Rhodobacter sphaeroides; Tyrosine | 2001 |
Regulative fine-tuning of the two novel DAHP isoenzymes aroFp and aroGp of the filamentous fungus Aspergillus nidulans.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Amino Acid Sequence; Amino Acids; Aspergillus nidulans; DNA, Complementary; Enzyme Inhibitors; Feedback; Gene Expression Regulation, Bacterial; Genes, Fungal; Genetic Complementation Test; Isoenzymes; Kinetics; Molecular Sequence Data; Phenylalanine; Temperature; Tyrosine | 2001 |
Removing a hydrogen bond in the dimer interface of Escherichia coli manganese superoxide dismutase alters structure and reactivity.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Crystallography, X-Ray; Dimerization; Enzyme Activation; Escherichia coli; Hydrogen Bonding; Manganese; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Superoxide Dismutase; Tyrosine | 2001 |
Roles of amino acid residues near the chromophore of photoactive yellow protein.
Topics: Amino Acids; Bacterial Proteins; Glutamic Acid; Halorhodospira halophila; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Photolysis; Photoreceptors, Microbial; Protons; Spectrophotometry; Threonine; Titrimetry; Tyrosine | 2001 |
Identification of inhibitor binding sites of the cAMP-specific phosphodiesterase 4.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Binding Sites; Blotting, Western; COS Cells; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Gene Deletion; Histidine; Humans; Inhibitory Concentration 50; Ions; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphodiesterase Inhibitors; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Rolipram; Tryptophan; Tyrosine; Zinc | 2001 |
Inter- and intra-molecular migration of peptide amide hydrogens during electrospray ionization.
Topics: Algorithms; Amides; Aspartic Acid; Deuterium; Fourier Analysis; Hydrogen; Oligopeptides; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2001 |
Effect of low levels of dietary tyrosine on the hair colour of cats.
Topics: Amino Acids; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Caseins; Cats; Dietary Proteins; Gelatin; Hair Color; Lactalbumin; Melanins; Nutritional Requirements; Phenylalanine; Proteins; Specific Pathogen-Free Organisms; Tyrosine | 2001 |
Active site of chondroitin AC lyase revealed by the structure of enzyme-oligosaccharide complexes and mutagenesis.
Topics: Amino Acid Sequence; Animals; Arginine; Binding Sites; Carbohydrate Sequence; Catalysis; Cattle; Chondroitin Lyases; Chondroitin Sulfates; Crystallography, X-Ray; Dermatan Sulfate; Flavobacterium; Histidine; Hyaluronic Acid; Macromolecular Substances; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Phenylalanine; Sharks; Structure-Activity Relationship; Substrate Specificity; Swine; Tyrosine | 2001 |
The structural basis for the perturbed pKa of the catalytic base in 4-oxalocrotonate tautomerase: kinetic and structural effects of mutations of Phe-50.
Topics: Alanine; Amino Acid Sequence; Catalysis; Circular Dichroism; Escherichia coli; Hydrogen-Ion Concentration; Isomerases; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Polymerase Chain Reaction; Proline; Recombinant Proteins; Structure-Activity Relationship; Titrimetry; Tyrosine | 2001 |
Molecular determinants for Csk-catalyzed tyrosine phosphorylation of the Src tail.
Topics: Amino Acid Substitution; Animals; Catalysis; Catalytic Domain; Chickens; CSK Tyrosine-Protein Kinase; Enzyme Activation; Kinetics; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Sequence Deletion; src Homology Domains; src-Family Kinases; Substrate Specificity; Tyrosine | 2001 |
Effects of noncovalent and covalent FAD binding on the redox and catalytic properties of p-cresol methylhydroxylase.
Topics: Amino Acid Substitution; Binding Sites; Catalysis; Cytochromes; Flavin-Adenine Dinucleotide; Flavoproteins; Mixed Function Oxygenases; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Pseudomonas putida; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tyrosine | 2001 |
Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue.
Topics: Botulinum Toxins; Catalytic Domain; Circular Dichroism; Hot Temperature; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Denaturation; Protein Structure, Secondary; Recombinant Proteins; src-Family Kinases; Tyrosine | 2001 |
Ff gene 5 protein has a high binding affinity for single-stranded phosphorothioate DNA.
Topics: Circular Dichroism; DNA, Single-Stranded; DNA, Viral; Inovirus; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Oligonucleotides; Organophosphates; Phenylalanine; Poly A; Protein Binding; Salts; Sodium Chloride; Thionucleotides; Titrimetry; Tyrosine; Viral Proteins | 2001 |
Tyrosine 331 and phenylalanine 334 in Clostridium perfringens alpha-toxin are essential for cytotoxic activity.
Topics: Animals; Aspartic Acid; Bacterial Toxins; Binding Sites; Calcium-Binding Proteins; Cell Line; Cell Membrane; Cricetinae; Isoleucine; Leucine; Liposomes; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Phospholipids; Type C Phospholipases; Tyrosine | 2001 |
Phe217 regulates the transfer of allosteric information across the subunit interface of the RecA protein filament.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Allosteric Site; Biosensing Techniques; Catalytic Domain; Dimaprit; DNA; DNA, Single-Stranded; Dose-Response Relationship, Drug; Kinetics; Microscopy, Electron; Models, Molecular; Models, Theoretical; Mutation; Phenylalanine; Protein Binding; Rec A Recombinases; Time Factors; Tyrosine | 2001 |
The cytoskeletal/non-muscle isoform of alpha-actinin is phosphorylated on its actin-binding domain by the focal adhesion kinase.
Topics: Actinin; Actins; Amino Acid Substitution; Binding Sites; Blood Platelets; Cloning, Molecular; Cytoskeleton; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein Isoforms; Protein-Tyrosine Kinases; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tyrosine | 2001 |
High-resolution crystal structure of apolipoprotein(a) kringle IV type 7: insights into ligand binding.
Topics: Animals; Apolipoproteins; Apoprotein(a); Arginine; Aspartic Acid; Binding Sites; Escherichia coli; Humans; Hydrogen Bonding; Kringles; Ligands; Lipoprotein(a); Models, Molecular; Phenylalanine; Plasminogen; Protein Binding; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Thrombin; Tyrosine | 2001 |
Identification of phosphorylation sites for Bruton's tyrosine kinase within the transcriptional regulator BAP/TFII-I.
Topics: Agammaglobulinaemia Tyrosine Kinase; Amino Acid Sequence; Animals; B-Lymphocytes; Binding Sites; Cell Line; COS Cells; DNA-Binding Proteins; Dose-Response Relationship, Drug; Epitopes; Escherichia coli; Genes, Reporter; Humans; Mice; Molecular Sequence Data; Mutation; Phenylalanine; Phosphorylation; Plasmids; Point Mutation; Precipitin Tests; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Recombinant Proteins; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Trypsin; Tyrosine | 2001 |
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
Topics: Alanine; Catalysis; Deuterium; Electron Transport; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tyrosine; UDPglucose 4-Epimerase | 2001 |
Identification of Src phosphorylation sites in the catenin p120ctn.
Topics: Animals; Binding Sites; Blotting, Western; Catenins; Cell Adhesion Molecules; Cell Line; COS Cells; Cytoplasm; Delta Catenin; DNA Mutational Analysis; Electrophoresis, Gel, Two-Dimensional; Epidermal Growth Factor; Gene Deletion; Genes, Dominant; Glutathione Transferase; Humans; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins pp60(c-src); Transfection; Tyrosine; Vanadates | 2001 |
Tyrosine and phenylalanine catabolism by Lactobacillus cheese flavor adjuncts.
Topics: Cheese; Chromatography, Micellar Electrokinetic Capillary; Lactobacillus; Oxidoreductases; Phenylalanine; Taste; Time Factors; Transaminases; Tyrosine | 2001 |
Synthesis of protected L-4-[sulfono(difluoromethyl)phenylalanine and its incorporation into a peptide.
Topics: Combinatorial Chemistry Techniques; Enzyme Inhibitors; Peptides; Phenylalanine; Tyrosine | 2001 |
Pseudoreversion of the catalytic activity of Y14F by the additional substitution(s) of tyrosine with phenylalanine in the hydrogen bond network of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Acrylamide; Amino Acid Substitution; Androstenedione; Catalysis; Crystallography, X-Ray; Deuterium Oxide; Enzyme Activation; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pseudomonas putida; Spectrometry, Fluorescence; Steroid Isomerases; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Tyrosine | 2001 |
Inhibitory effect of a two day fast on reactive oxygen species (ROS) generation by leucocytes and plasma ortho-tyrosine and meta-tyrosine concentrations.
Topics: Adult; Fasting; Humans; Middle Aged; Monocytes; NADPH Oxidases; Neutrophils; Osmolar Concentration; Phenylalanine; Phosphoproteins; Reactive Oxygen Species; Time Factors; Tyrosine | 2001 |
[Maternal phenylketonuria].
Topics: Adult; Congenital Abnormalities; Diet, Protein-Restricted; Energy Intake; Female; Fetal Growth Retardation; Gestational Age; Humans; Nutritional Requirements; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Prenatal Care; Risk Factors; Tyrosine | 2001 |
Persistent tyrosinemia detected by thin-layer chromatography.
Topics: Chromatography, Thin Layer; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Tyrosine; Tyrosinemias | 1999 |
An essential residue in the flexible peptide linking the two idiosynchratic domains of bacterial tyrosyl-tRNA synthetases.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Enzyme Activation; Geobacillus stearothermophilus; Kinetics; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Protein Structure, Tertiary; Sequence Alignment; Sequence Homology, Amino Acid; Structure-Activity Relationship; Thermodynamics; Tryptophan; Tyrosine; Tyrosine-tRNA Ligase | 2001 |
Selenotyrosine and related phenylalanine derivatives.
Topics: Biochemistry; Organoselenium Compounds; Phenylalanine; Tyrosine | 2001 |
Role of aromatic stacking interactions in the modulation of the two-electron reduction potentials of flavin and substrate/product in Megasphaera elsdenii short-chain acyl-coenzyme A dehydrogenase.
Topics: Acyl Coenzyme A; Acyl-CoA Dehydrogenase; Binding Sites; Catalysis; Electrochemistry; Electron Transport; Fatty Acid Desaturases; Flavin-Adenine Dinucleotide; Macromolecular Substances; Mutagenesis, Site-Directed; Oxidation-Reduction; Peptostreptococcus; Phenylalanine; Recombinant Proteins; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Tryptophan; Tyrosine | 2001 |
Autocatalytic tyrosine-phosphorylation of protein kinase CK2 alpha and alpha' subunits: implication of Tyr182.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Casein Kinase II; Emodin; Enzyme Inhibitors; Escherichia coli; Heparin; Kinetics; Models, Molecular; Oligopeptides; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein Serine-Threonine Kinases; Protein Subunits; Recombinant Proteins; Substrate Specificity; Tyrosine | 2001 |
Vaccinia topoisomerase mutants illuminate conformational changes during closure of the protein clamp and assembly of a functional active site.
Topics: Amino Acid Sequence; Asparagine; Base Sequence; Binding Sites; Catalytic Domain; DNA; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Magnesium Chloride; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Serine; Sodium Chloride; Time Factors; Tyrosine; Vaccinia virus | 2001 |
Synergistic interactions of multiple mutations on catalysis during the hydroxylation reaction of p-hydroxybenzoate hydroxylase: studies of the Lys297Met, Asn300Asp, and Tyr385Phe mutants reconstituted with 8-Cl-flavin.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Alanine; Amino Acid Substitution; Anaerobiosis; Asparagine; Aspartic Acid; Catalysis; Flavin-Adenine Dinucleotide; Hydroxylation; Lysine; Methionine; Mutagenesis, Site-Directed; Oxidation-Reduction; Parabens; Phenylalanine; Riboflavin; Serine; Spectrophotometry; Substrate Specificity; Tyrosine | 2001 |
Tryptophan residues at subunit interfaces used as fluorescence probes to investigate homotropic and heterotropic regulation of aspartate transcarbamylase.
Topics: Allosteric Regulation; Asparagine; Aspartate Carbamoyltransferase; Aspartic Acid; Escherichia coli; Fluorescent Dyes; Kinetics; Peptide Fragments; Phenylalanine; Phosphonoacetic Acid; Spectrometry, Fluorescence; Substrate Specificity; Titrimetry; Tryptophan; Tyrosine | 2001 |
Roles for beta(pat-3) integrins in development and function of Caenorhabditis elegans muscles and gonads.
Topics: Actins; Alleles; Amino Acid Sequence; Animals; Animals, Genetically Modified; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cell Movement; Cytoplasm; DNA, Complementary; Epitopes; Genes, Dominant; Gonads; Hemagglutinins; Integrin beta Chains; Integrins; Molecular Sequence Data; Muscles; Mutation; Ovulation; Phenotype; Phenylalanine; Protein Structure, Tertiary; Transgenes; Tyrosine | 2001 |
Plasma phenylalanine is associated with decreased serum ubiquinone-10 concentrations in phenylketonuria.
Topics: Adolescent; Adult; Child; Child, Preschool; Cholesterol; Cholesterol, Dietary; Humans; Infant; Linear Models; Phenylalanine; Phenylketonurias; Tyrosine; Ubiquinone | 2001 |
Amino acids do not suppress proteolysis in premature neonates.
Topics: Amino Acids; Blood Glucose; Female; Gestational Age; Humans; Hydroxylation; Infant, Newborn; Infant, Premature; Infusions, Intravenous; Insulin; Kinetics; Leucine; Male; Oxidation-Reduction; Oxygen Consumption; Phenylalanine; Proteins; Tyrosine | 2001 |
Four tyrosine residues in phospholipase C-gamma 2, identified as Btk-dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling.
Topics: Agammaglobulinaemia Tyrosine Kinase; Amino Acid Sequence; Animals; Binding Sites; Calcium; Cell Line; DNA, Complementary; Enzyme Activation; Genetic Vectors; Glutathione Transferase; Humans; Hydrolysis; Immunoblotting; Isoenzymes; Molecular Sequence Data; Mutation; Phenylalanine; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Receptors, Antigen, B-Cell; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Time Factors; Transfection; Type C Phospholipases; Tyrosine | 2001 |
The role of Tyr248 probed by mutant bovine carboxypeptidase A: insight into the catalytic mechanism of carboxypeptidase A.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Base Sequence; Carboxypeptidases; Carboxypeptidases A; Catalysis; Cattle; DNA Primers; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Recombinant Proteins; Substrate Specificity; Tyrosine | 2001 |
Interference with immunoglobulin (Ig)alpha immunoreceptor tyrosine-based activation motif (ITAM) phosphorylation modulates or blocks B cell development, depending on the availability of an Igbeta cytoplasmic tail.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Antigens, CD; B-Lymphocytes; Base Sequence; CD79 Antigens; Cytoplasm; DNA; Mice; Molecular Sequence Data; Phenylalanine; Phosphorylation; Receptors, Fc; Tyrosine | 2001 |
Contribution of aromatic-aromatic interactions to the anomalous pK(a) of tyrosine-9 and the C-terminal dynamics of glutathione S-transferase A1-1.
Topics: Animals; Escherichia coli; Glutathione; Glutathione Transferase; Kinetics; Ligands; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Rats; Recombinant Fusion Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tyrosine | 2001 |
3D model for TM region of the AT-1 receptor in complex with angiotensin II independently validated by site-directed mutagenesis data.
Topics: Amino Acid Sequence; Crystallography, X-Ray; Histidine; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Rhodopsin; Signal Transduction; Tyrosine | 2001 |
Role of Phe286 in the recognition mechanism of cyclomaltooligosaccharides (cyclodextrins) by Thermoactinomyces vulgaris R-47 alpha-amylase 2 (TVAII). X-ray structures of the mutant TVAIIs, F286A and F286Y, and kinetic analyses of the Phe286-replaced mutan
Topics: Alanine; alpha-Amylases; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cyclodextrins; Kinetics; Micromonosporaceae; Mutagenesis, Site-Directed; Phenylalanine; Tyrosine | 2001 |
The emerging periplasm-localized subclass of AroQ chorismate mutases, exemplified by those from Salmonella typhimurium and Pseudomonas aeruginosa.
Topics: Amino Acid Sequence; Chorismate Mutase; Chorismic Acid; Cloning, Molecular; Cytoplasm; Kinetics; Molecular Sequence Data; Molecular Weight; Multigene Family; Periplasm; Phenylalanine; Protein Structure, Tertiary; Pseudomonas aeruginosa; Recombinant Proteins; Salmonella typhimurium; Sequence Alignment; Substrate Specificity; Transaminases; Tyrosine | 2001 |
An extreme-halophile archaebacterium possesses the interlock type of prephenate dehydratase characteristic of the Gram-positive eubacteria.
Topics: Alanine; Allosteric Regulation; Amino Acids; Archaea; Evolution, Molecular; Gram-Positive Bacteria; Halobacterium; Mutation; Phenylalanine; Phylogeny; Prephenate Dehydratase; Sodium Chloride; Tyrosine | 1988 |
Nitrogen recycling during phenylpropanoid metabolism in sweet potato tubers.
Topics: Ammonium Chloride; Darkness; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Glutamic Acid; Glutamine; Indans; Light; Magnetic Resonance Spectroscopy; Nitrogen; Nitrogen Isotopes; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Stems; Quaternary Ammonium Compounds; Solanaceae; Time Factors; Tyrosine | 1998 |
Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2.
Topics: Amino Acid Sequence; Amino Acids; Chromatography, Thin Layer; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Ions; Magnesium; Molecular Sequence Data; Oxytocin; Peptides; Phenylalanine; Tyrosine | 2001 |
Effect of electroconvulsive therapy on biopterin and large neutral amino acids in severe, medication-resistant depression.
Topics: Adult; Aged; Amino Acids, Neutral; Biopterins; Depressive Disorder, Major; Electroconvulsive Therapy; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Neopterin; Phenylalanine; Psychiatric Status Rating Scales; Psychotic Disorders; Reference Values; Treatment Outcome; Tryptophan; Tyrosine; Valine | 2001 |
Treatable neurotransmitter deficiency in mild phenylketonuria.
Topics: Adolescent; Antioxidants; Biogenic Monoamines; Biopterins; Female; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 2001 |
Tyrosine hydrogen bonds make a large contribution to protein stability.
Topics: Amino Acid Substitution; Circular Dichroism; Crystallography, X-Ray; Hydrogen Bonding; Isoenzymes; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Denaturation; Ribonucleases; Streptomyces; Temperature; Thermodynamics; Tyrosine | 2001 |
In vitro selection of DNA aptamers that bind L-tyrosinamide.
Topics: Base Sequence; Chromatography, Affinity; Combinatorial Chemistry Techniques; DNA Topoisomerases, Type I; DNA, Single-Stranded; Drug Design; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Genetic Techniques; Molecular Sequence Data; Molecular Structure; Oligodeoxyribonucleotides; Oligonucleotides; Phenylalanine; Polymerase Chain Reaction; RNA; Sequence Alignment; Sequence Analysis, DNA; Stereoisomerism; Taq Polymerase; Topoisomerase I Inhibitors; Tyrosine | 2001 |
Early photocycle kinetic behavior of the E46A and Y42F mutants of photoactive yellow protein: femtosecond spectroscopy.
Topics: Alanine; Bacterial Proteins; Glutamic Acid; Halorhodospira halophila; Hydrogen Bonding; Kinetics; Light; Mutagenesis, Site-Directed; Phenylalanine; Photochemistry; Photoreceptors, Microbial; Spectrophotometry; Tyrosine | 2001 |
The roles of the N-terminal portions of various tachykinins in promoting salivation.
Topics: Analysis of Variance; Animals; Eledoisin; Injections, Intraperitoneal; Isoleucine; Kassinin; Male; Models, Animal; Neurokinin A; Neurokinin B; Phenylalanine; Rats; Rats, Sprague-Dawley; Salivation; Serine; Statistics as Topic; Submandibular Gland; Tachykinins; Tyrosine; Valine | 2001 |
Manipulating the direction of electron transfer in the bacterial reaction center by swapping Phe for Tyr near BChl(M) (L181) and Tyr for Phe near BChl(L) (M208).
Topics: Electron Transport; Kinetics; Light-Harvesting Protein Complexes; Mutation; Phenylalanine; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Tyrosine | 2001 |
Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity.
Topics: Amino Acid Sequence; Amino Acids; Animals; Baculoviridae; Binding Sites; Blotting, Western; Carbon-Carbon Ligases; Catalysis; Catalytic Domain; Cell Line; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen-Ion Concentration; Insecta; Ions; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptides; Phenylalanine; Protein Binding; Protein Precursors; Protein Structure, Tertiary; Prothrombin; Rabbits; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Tyrosine; Vitamin K | 2001 |
Saccharomyces cerevisiae leukotriene A4 hydrolase: formation of leukotriene B4 and identification of catalytic residues.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Enzyme Inhibitors; Epoxide Hydrolases; Escherichia coli; Glutamic Acid; Humans; Hydrolysis; Leukotriene A4; Leukotriene B4; Leukotrienes; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Saccharomyces cerevisiae; Spodoptera; Tyrosine; Zinc | 2001 |
Uniaxial cyclic stretch induces focal adhesion kinase (FAK) tyrosine phosphorylation followed by mitogen-activated protein kinase (MAPK) activation.
Topics: Amino Acid Substitution; Animals; Calcium; Cell Membrane; Cells, Cultured; Enzyme Activation; Fibroblasts; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mechanoreceptors; Mitogen-Activated Protein Kinases; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Rats; Transfection; Tyrosine | 2001 |
Conserved tyrosine-369 in the active site of Escherichia coli copper amine oxidase is not essential.
Topics: Amine Oxidase (Copper-Containing); Binding Sites; Conserved Sequence; Crystallography, X-Ray; Dimerization; Electrons; Enzyme Inhibitors; Escherichia coli; Hydrogen; Hydrogen-Ion Concentration; Kinetics; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Pyridones; Spectrophotometry; Time Factors; Tyrosine; Ultraviolet Rays | 2001 |
Physical properties of human polynucleotide kinase: hydrodynamic and spectroscopic studies.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Circular Dichroism; Cloning, Molecular; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Humans; Phenylalanine; Polymerase Chain Reaction; Polynucleotide 5'-Hydroxyl-Kinase; Protein Binding; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays; Water | 2001 |
Gas chromatographic-mass spectrometric method for quantitation of phenylalanine and tyrosine in serum.
Topics: Fetal Blood; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Phenylalanine; Reference Standards; Reference Values; Tyrosine | 2001 |
Atypical protein kinase Czeta suppresses migration of mouse melanoma cells.
Topics: Animals; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Cell Adhesion; Cell Line; Cell Movement; Cell Separation; Cells, Cultured; DNA, Complementary; Down-Regulation; Intracellular Signaling Peptides and Proteins; Melanins; Melanoma, Experimental; Mice; Mutagenesis, Site-Directed; Neoplasm Metastasis; Phenylalanine; Precipitin Tests; Protein Kinase C; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Tyrosine | 2001 |
Specific amino acid deficiency alters the expression of genes in human melanoma and other tumor cell lines.
Topics: Blotting, Western; Breast Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Melanoma; Mitogen-Activated Protein Kinase Kinases; Phenylalanine; Phosphorylation; Prostatic Neoplasms; RNA, Messenger; RNA, Neoplasm; Tumor Cells, Cultured; Tyrosine | 2001 |
The purification and characterization of an 88-kDa Porphyromonas endodontalis 35406 protease.
Topics: Aminopeptidases; Angiotensins; Bradykinin; Chromogenic Compounds; Collagen Type IV; Cystinyl Aminopeptidase; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Fibrinogen; Fibronectins; Hot Temperature; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Lysine Carboxypeptidase; Molecular Weight; Oxidants; Oxidation-Reduction; Phenylalanine; Porphyromonas; Sodium Dodecyl Sulfate; Surface-Active Agents; Temperature; Tyrosine; Vasopressins | 2001 |
Identification of tyrosine residues involved in ligand recognition by the phosphatidylinositol 3-kinase Src homology 3 domain: circular dichroism and UV resonance Raman studies.
Topics: Amino Acid Substitution; Circular Dichroism; Histidine; Humans; Ligands; Mutagenesis, Site-Directed; Phenylalanine; Phosphatidylinositol 3-Kinases; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; src Homology Domains; Tyrosine | 2001 |
Effect of maternal blood phenylalanine level on mouse maternal phenylketonuria offspring.
Topics: Abortion, Spontaneous; Animals; Disease Models, Animal; Embryonic and Fetal Development; Female; Fetal Diseases; Humans; Male; Mice; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Tyrosine | 2001 |
Catalytic function of the residues of phenylalanine and tyrosine conserved in squalene-hopene cyclases.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Gram-Positive Endospore-Forming Rods; Intramolecular Transferases; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tyrosine | 2001 |
Large neutral amino acids auto exchange when infused by microdialysis into the rat brain: implication for maple syrup urine disease and phenylketonuria.
Topics: Amino Acid Transport Systems, Neutral; Amino Acids, Cyclic; Amino Acids, Neutral; Animals; Binding, Competitive; Biological Transport; Blood-Brain Barrier; Brain; Extracellular Space; Hippocampus; Keto Acids; Leucine; Maple Syrup Urine Disease; Microdialysis; Models, Biological; Nerve Tissue Proteins; Neurons; Phenylalanine; Phenylketonurias; Rats; Tyrosine | 2002 |
Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes.
Topics: Animals; Antineoplastic Agents; Bryostatins; Cell Differentiation; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoblotting; Isoenzymes; Keratinocytes; Lactones; Macrolides; Mice; Mice, Inbred BALB C; Oligonucleotides, Antisense; Phenotype; Phenylalanine; Phosphorylation; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Pyridines; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; src-Family Kinases; Subcellular Fractions; Transfection; Tyrosine | 2002 |
Enzymatic decarboxylation of tyrosine and phenylalanine to enhance volatility for high-precision isotopic analysis.
Topics: Amino Acids; Animals; Carboxy-Lyases; Humans; Isotopes; Mass Spectrometry; Phenylalanine; Tyrosine | 2002 |
Long-term therapy with NTBC and tyrosine-restricted diet in a murine model of hereditary tyrosinemia type I.
Topics: Animals; Cyclohexanones; Diet; Disease Models, Animal; Enzyme Inhibitors; Hydrolases; Mice; Mice, Knockout; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias | 2002 |
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis.
Topics: Adult; Aged; Antioxidants; Aorta; Arteriosclerosis; Cholesterol; Cholesterol Esters; Disease Progression; Humans; Lipid Metabolism; Middle Aged; Oxidation-Reduction; Phenylalanine; Proteins; Tyrosine | 2002 |
Quantitative determination of plasma phenylalanine and tyrosine by electrospray ionization tandem mass spectrometry.
Topics: Humans; Infant; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Quality Control; Reference Values; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2002 |
Site-directed rotational resonance solid-state NMR distance measurements probe structure and mechanism in the transmembrane domain of the serine bacterial chemoreceptor.
Topics: Carbon Isotopes; Cysteine; Glycine; Magnetic Resonance Spectroscopy; Membrane Proteins; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Receptors, Amino Acid; Rotation; Serine Endopeptidases; Tyrosine | 2002 |
Endogenous glycine and tyrosine production is maintained in adults consuming a marginal-protein diet.
Topics: Adaptation, Physiological; Adult; Biological Availability; Carbon Isotopes; Dietary Proteins; Female; Glycine; Humans; Intestinal Absorption; Male; Nitrogen; Nutritional Requirements; Phenylalanine; Tyrosine | 2002 |
Active-site residues governing high steroid isomerase activity in human glutathione transferase A3-3.
Topics: Binding Sites; Escherichia coli; Glutathione; Glutathione Transferase; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Steroid Isomerases; Substrate Specificity; Sulfhydryl Compounds; Tyrosine | 2002 |
The peptide repertoires of HLA-B27 subtypes differentially associated to spondyloarthropathy (B*2704 and B*2706) differ by specific changes at three anchor positions.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Arginine; Cell Line; Chromatography, High Pressure Liquid; Epitopes; HLA-B27 Antigen; Humans; Immunoglobulin Allotypes; Ligands; Mass Spectrometry; Molecular Sequence Data; Peptides; Phenylalanine; Polymorphism, Genetic; Protein Structure, Tertiary; Spondylitis; T-Lymphocytes; T-Lymphocytes, Cytotoxic; Tyrosine | 2002 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
Phi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal protein.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacteriophages; Catalytic Domain; Conserved Sequence; Deoxyadenine Nucleotides; DNA; DNA Replication; DNA-Directed DNA Polymerase; Histidine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sequence Alignment; Tyrosine; Viral Proteins | 2002 |
Substrate activation in acetylcholinesterase induced by low pH or mutation in the pi-cation subsite.
Topics: Acetylcholinesterase; Acetylthiocholine; Binding Sites; Butyrylcholinesterase; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Tyrosine | 2002 |
CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion.
Topics: Amino Acid Sequence; Cell Adhesion; Cell Line; Cell Membrane; Chemokine CX3CL1; Chemokines, CX3C; CX3C Chemokine Receptor 1; DNA, Complementary; Dose-Response Relationship, Drug; Flow Cytometry; Green Fluorescent Proteins; Humans; K562 Cells; Kinetics; Leukocytes; Luminescent Proteins; Membrane Proteins; Molecular Sequence Data; Mutation; Phenylalanine; Receptors, Cytokine; Receptors, HIV; Sequence Homology, Amino Acid; Signal Transduction; Surface Plasmon Resonance; Time Factors; Transfection; Tyrosine | 2002 |
[Effect of precursors on the production of coumarins in a suspension culture of Angelica archangelica L].
Topics: Angelica archangelica; Cinnamates; Coumarins; Culture Techniques; Phenylalanine; Plants, Medicinal; Tyrosine | 2002 |
Mutations of tyrosine 537 in the human estrogen receptor-alpha selectively alter the receptor's affinity for estradiol and the kinetics of the interaction.
Topics: Animals; Cell Line; Crystallography, X-Ray; DNA, Complementary; Dose-Response Relationship, Drug; Estradiol; Estrogen Receptor alpha; Glutamic Acid; Humans; Hydrogen Bonding; Insecta; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Peptides; Phenylalanine; Protein Binding; Protein Conformation; Receptors, Estrogen; Serine; Time Factors; Transfection; Tyrosine | 2002 |
Modelling the phenylalanine blood level response during treatment of phenylketonuria.
Topics: Child; Child, Preschool; Computer Simulation; Female; Humans; Kinetics; Male; Models, Biological; Phenotype; Phenylalanine; Phenylketonurias; Protein Biosynthesis; Software; Tyrosine | 2001 |
Tyrosinaemia type II: an easily diagnosed metabolic disorder with a rewarding therapeutic response.
Topics: Adult; Child; Chromatography, High Pressure Liquid; Female; Humans; Intellectual Disability; Male; Mass Spectrometry; Phenylalanine; Retrospective Studies; Tyrosine; Tyrosinemias | 1999 |
Synthesis of two neuromedin U (NMU) analogues and their comparative effect of reducing food intake in rats.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Feeding Behavior; Injections, Intraventricular; Male; Molecular Sequence Data; Neuropeptides; Phenylalanine; Protein Engineering; Rats; Rats, Wistar; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship; Tyrosine | 2002 |
Function assignment to conserved residues in mammalian alkaline phosphatases.
Topics: Alkaline Phosphatase; Animals; Binding Sites; Conserved Sequence; Cysteine; Disulfides; Dose-Response Relationship, Drug; Epitopes; Histidine; Humans; Kinetics; Leucine; Ligands; Magnesium; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Software; Spectrometry, Fluorescence; Time Factors; Tyrosine; Zinc | 2002 |
Kinetic studies on the oxidation of cytochrome b(5) Phe35 mutants with cytochrome c, plastocyanin and inorganic complexes.
Topics: Cytochrome c Group; Cytochromes b5; Edetic Acid; Electron Transport; Inorganic Chemicals; Iron; Kinetics; Leucine; Mutation; Oxidation-Reduction; Phenylalanine; Plastocyanin; Spectrophotometry, Ultraviolet; Tyrosine | 2002 |
Substitutions of Phe61 located in the vicinity of template 5'-overhang influence polymerase fidelity and nucleoside analog sensitivity of HIV-1 reverse transcriptase.
Topics: Adenosine Triphosphate; Alanine; Base Pair Mismatch; Dimerization; DNA; HIV Reverse Transcriptase; Inhibitory Concentration 50; Kinetics; Leucine; Mutagenesis; Mutation; Phenotype; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Thymine Nucleotides; Tryptophan; Tyrosine | 2002 |
Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Catalysis; Cell Transformation, Neoplastic; Drosophila Proteins; Humans; Mice; Multiple Endocrine Neoplasia Type 2a; Mutagenesis; Phenylalanine; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; Receptor Protein-Tyrosine Kinases; src-Family Kinases; Transfection; Tyrosine | 2002 |
Unique activation mechanism of protein kinase CK2. The N-terminal segment is essential for constitutive activity of the catalytic subunit but not of the holoenzyme.
Topics: Adenosine Triphosphate; Alanine; Amino Acid Sequence; Casein Kinase II; Catalysis; Catalytic Domain; Enzyme Activation; Glutamic Acid; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Recombinant Proteins; Temperature; Tyrosine | 2002 |
Unspecific hydrophobic stabilization of folding transition states.
Topics: Biophysics; Cell Nucleus; Dose-Response Relationship, Drug; Escherichia coli; Kinetics; Models, Molecular; Mutation; Phenylalanine; Plasmids; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Spectrin; src Homology Domains; Temperature; Thermodynamics; Tyrosine; Urea | 2002 |
Threonine-124 and phenylalanine-448 in Citrobacter freundii tyrosine phenol-lyase are necessary for activity with L-tyrosine.
Topics: Amino Acid Sequence; Binding Sites; Citrobacter freundii; Escherichia coli; Models, Chemical; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pyridoxal Phosphate; Sequence Alignment; Structure-Activity Relationship; Threonine; Tyrosine; Tyrosine Phenol-Lyase | 2002 |
Gravity and land plant evolution: experimental induction of lignification by simulated hypergravity and water stress.
Topics: Biological Evolution; Centrifugation; Cotyledon; Cucumis sativus; Fabaceae; Hypergravity; Lignin; Magnoliopsida; Phenylalanine; Plant Physiological Phenomena; Plant Roots; Plant Shoots; Stress, Mechanical; Tyrosine; Water | 1980 |
Specific inhibition of N-methyl-D-aspartate receptor function in rat hippocampal neurons by L-phenylalanine at concentrations observed during phenylketonuria.
Topics: Animals; Animals, Newborn; Binding Sites; Cells, Cultured; Dose-Response Relationship, Drug; Glycine; Hippocampus; Membrane Potentials; Neurons; Patch-Clamp Techniques; Phenylalanine; Phenylketonurias; Rats; Receptors, N-Methyl-D-Aspartate; Tyrosine | 2002 |
DALDA analogues containing alpha-hydroxymethylamino acids.
Topics: Amino Acids; Analgesics; Animals; Guinea Pigs; Ileum; Male; Oligopeptides; Opioid Peptides; Peptides; Phenylalanine; Tyrosine; Vas Deferens | 2001 |
Optimizing an artificial metabolic pathway: engineering the cofactor specificity of Corynebacterium 2,5-diketo-D-gluconic acid reductase for use in vitamin C biosynthesis.
Topics: Alanine; Amino Acid Substitution; Ascorbic Acid; Binding Sites; Corynebacterium; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gluconates; Glycine; Kinetics; Mutagenesis, Site-Directed; NAD; NADP; Phenylalanine; Recombinant Fusion Proteins; Sugar Alcohol Dehydrogenases; Thermodynamics; Tyrosine | 2002 |
EPR studies on a stable sulfinyl radical observed in the iron-oxygen-reconstituted Y177F/I263C protein R2 double mutant of ribonucleotide reductase from mouse.
Topics: Animals; Cysteine; Electron Spin Resonance Spectroscopy; Enzyme Activation; Escherichia coli; Ferrous Compounds; Free Radicals; Isoleucine; Mice; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Recombinant Proteins; Ribonucleotide Reductases; Spectrophotometry; Tyrosine | 2002 |
The nature of intermolecular interactions between aromatic amino acid residues.
Topics: Amino Acids, Aromatic; Models, Molecular; Molecular Structure; Phenylalanine; Static Electricity; Tryptophan; Tyrosine | 2002 |
Stacking and T-shape competition in aromatic-aromatic amino acid interactions.
Topics: Computer Simulation; Dipeptides; Models, Chemical; Models, Molecular; Phenylalanine; Protein Conformation; Surface Properties; Tyrosine | 2002 |
Spectral tuning in the mammalian short-wavelength sensitive cone pigments.
Topics: Amino Acid Substitution; Animals; Cattle; Glutamic Acid; Light; Mice; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Secondary; Rod Opsins; Species Specificity; Spectrum Analysis; Transducin; Tyrosine; Ultraviolet Rays | 2002 |
The presence of a single tyrosine residue at the carboxyl domain of vascular endothelial growth factor receptor-2/FLK-1 regulates its autophosphorylation and activation of signaling molecules.
Topics: Animals; Blotting, Western; DNA, Complementary; Endothelium, Vascular; Enzyme Activation; Glutamic Acid; Isoenzymes; Ligands; MAP Kinase Signaling System; Mice; Mutagenesis, Site-Directed; Phenylalanine; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; src-Family Kinases; Swine; Time Factors; Type C Phospholipases; Tyrosine | 2002 |
Structure function analysis of interleukin 7: requirement for an aromatic ring at position 143 of helix D.
Topics: Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Histidine; Humans; Inhibitory Concentration 50; Interleukin-7; Mice; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Plasmids; Proline; Protein Binding; Protein Structure, Tertiary; Receptors, Interleukin-7; Signal Transduction; Tryptophan; Tyrosine | 2002 |
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study.
Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine | 2002 |
Comparative time-courses of copper-ion-mediated protein and lipid oxidation in low-density lipoprotein.
Topics: alpha-Tocopherol; Antioxidants; Apolipoprotein B-100; Apolipoproteins B; Copper; Dihydroxyphenylalanine; Humans; Lipid Peroxidation; Lipids; Lipoproteins, LDL; Oxidation-Reduction; Phenylalanine; Spectrometry, Fluorescence; Time Factors; Tryptophan; Tyrosine | 2002 |
Identification of a new class of inhibitors of the voltage-gated potassium channel, Kv1.3, with immunosuppressant properties.
Topics: Alanine; Animals; Binding Sites; Cell Line; CHO Cells; Cricetinae; Cyclohexanones; Guinea Pigs; Humans; Immunosuppressive Agents; Intracellular Fluid; Kv1.3 Potassium Channel; Lymphocyte Activation; Monoiodotyrosine; Patch-Clamp Techniques; Phenylalanine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Rats; Scorpion Venoms; T-Lymphocytes; Transfection; Triterpenes; Tyrosine | 2002 |
Activation of caspases and cleavage of Bid are required for tyrosine and phenylalanine deficiency-induced apoptosis of human A375 melanoma cells.
Topics: Amino Acid Chloromethyl Ketones; Amino Acids, Aromatic; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase Inhibitors; Caspases; Cysteine Proteinase Inhibitors; Cytochrome c Group; Fas Ligand Protein; fas Receptor; Humans; Ligands; Melanoma; Membrane Glycoproteins; Mitochondria; Models, Biological; Phenylalanine; Time Factors; Tumor Cells, Cultured; Tyrosine; Ubiquinone | 2002 |
Molecular modeling and site-specific mutagenesis of the histamine-binding site of the histamine H4 receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Asparagine; Binding Sites; Calcium; Cells, Cultured; Histamine; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H4; Sequence Homology, Amino Acid; Serine; Tyrosine | 2002 |
Rational design to block amino acid editing of a tRNA synthetase.
Topics: Binding Sites; Escherichia coli; Isoleucine; Leucine; Leucine-tRNA Ligase; Methionine; Models, Molecular; Mutagenesis; Phenylalanine; Polymerase Chain Reaction; Protein Conformation; Tyrosine | 2002 |
Site-directed mutagenesis of tyrosine 118 within the central constriction site of the LamB (maltoporin) channel of Escherichia coli. II. Effect on maltose and maltooligosaccharide binding kinetics.
Topics: Bacterial Outer Membrane Proteins; Biological Transport; Biophysical Phenomena; Biophysics; Carbohydrate Metabolism; Carbohydrates; Crystallography, X-Ray; Escherichia coli; Glucans; Kinetics; Lipid Bilayers; Lipids; Maltose; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oligosaccharides; Phenylalanine; Porins; Protein Binding; Receptors, Virus; Time Factors; Trisaccharides; Tryptophan; Tyrosine | 2002 |
Role of Dok1 in cell signaling mediated by RET tyrosine kinase.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; Cell Line; DNA-Binding Proteins; Drosophila Proteins; Enzyme Activation; Glutathione Transferase; Immunoblotting; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Models, Biological; Multiple Endocrine Neoplasia Type 2b; Mutation; Oncogene Proteins; Phenylalanine; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ret; ras GTPase-Activating Proteins; ras Proteins; Receptor Protein-Tyrosine Kinases; RNA-Binding Proteins; Signal Transduction; Two-Hybrid System Techniques; Tyrosine | 2002 |
Increased frequency of cysteine, tyrosine, and phenylalanine residues since the last universal ancestor.
Topics: Amino Acid Sequence; Conserved Sequence; Cysteine; Databases, Protein; Evolution, Molecular; Genetic Code; Models, Genetic; Phenylalanine; Proteome; Time Factors; Tyrosine | 2002 |
Cats require more dietary phenylalanine or tyrosine for melanin deposition in hair than for maximal growth.
Topics: Animals; Cats; Diet; Dose-Response Relationship, Drug; Hair; Hair Color; Melanins; Nutritional Requirements; Osmolar Concentration; Phenylalanine; Pyrroles; Tyrosine | 2002 |
The molecular mechanism for the spectral shifts between vertebrate ultraviolet- and violet-sensitive cone visual pigments.
Topics: Animals; Biological Evolution; Cattle; DNA, Complementary; Genetic Vectors; Goldfish; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phylogeny; Protein Conformation; Retinal Pigments; Rod Opsins; Sequence Homology, Amino Acid; Spectrophotometry; Swine; Tyrosine; Ultraviolet Rays | 2002 |
Familial mutation in the testis-determining gene SRY shared by an XY female and her normal father.
Topics: Amino Acid Substitution; Base Sequence; DNA-Binding Proteins; Fathers; Female; Genes, sry; Gonadal Dysgenesis, 46,XY; HMG-Box Domains; Humans; Male; Mutation; Nuclear Proteins; Phenylalanine; Polymerase Chain Reaction; Reference Values; Sex-Determining Region Y Protein; Testis; Transcription Factors; Tyrosine | 2002 |
Thin layer chromatographical detection of tyrosine produced from L-[U-(14)C]phenylalanine by ruminal microbes.
Topics: Animals; Bacteria; Carbon Radioisotopes; Chromatography, Thin Layer; Eukaryota; Goats; Phenylalanine; Rumen; Tyrosine | 2002 |
Mutation of tyrosine 332 to phenylalanine converts dopa decarboxylase into a decarboxylation-dependent oxidative deaminase.
Topics: Amines; Amino Acids; Binding Sites; Blotting, Western; Catalysis; Dopa Decarboxylase; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Oxygen Consumption; Phenylalanine; Protein Binding; Tyrosine | 2002 |
Vibrational modes of tyrosines in cytochrome c oxidase from Paracoccus denitrificans: FTIR and electrochemical studies on Tyr-D4-labeled and on Tyr280His and Tyr35Phe mutant enzymes.
Topics: Electrochemistry; Electron Transport Complex IV; Histidine; Mutation; Paracoccus denitrificans; Phenylalanine; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2002 |
TEL-JAK2 constitutively activates the extracellular signal-regulated kinase (ERK), stress-activated protein/Jun kinase (SAPK/JNK), and p38 signaling pathways.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Line; Enzyme Activation; GRB2 Adaptor Protein; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinases; Mutation; Oncogene Proteins, Fusion; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Proteins; ras Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine | 2002 |
Clinical resistance to the kinase inhibitor STI-571 in chronic myeloid leukemia by mutation of Tyr-253 in the Abl kinase domain P-loop.
Topics: Antineoplastic Agents; Benzamides; Drug Resistance; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Phenylalanine; Phosphorylation; Piperazines; Point Mutation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Pyrimidines; Tyrosine | 2002 |
A conserved Tyr residue is required for sugar selectivity in a Pol alpha DNA polymerase.
Topics: Alanine; Arabinofuranosylcytosine Triphosphate; Bacteriophage T4; Binding Sites; Conserved Sequence; Deoxycytosine Nucleotides; Deoxyribonucleosides; Dideoxynucleotides; DNA Polymerase I; DNA Primers; DNA-Directed DNA Polymerase; Enzyme Inhibitors; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Substrate Specificity; Tyrosine; Viral Proteins | 2002 |
Characterization of the amino acids involved in substrate specificity of nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans.
Topics: Amino Acid Sequence; Arginine; Catalysis; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Mutation; Phenylalanine; Phosphates; Sequence Homology, Amino Acid; Streptococcus mutans; Substrate Specificity; Time Factors; Tyrosine | 2002 |
X-ray crystallography, CD and kinetic studies revealed the essence of the abnormal behaviors of the cytochrome b5 Phe35-->Tyr mutant.
Topics: Animals; Apoproteins; Binding Sites; Cattle; Circular Dichroism; Crystallography, X-Ray; Cytochromes b5; Enzyme Stability; Kinetics; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Myoglobin; Oxidation-Reduction; Phenylalanine; Protein Denaturation; Protein Folding; Structure-Activity Relationship; Tyrosine | 2002 |
IL-2 receptor signaling through the Shb adapter protein in T and NK cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; Binding Sites; CD56 Antigen; Cell Division; Cell Line; COS Cells; DNA; Humans; Janus Kinase 1; Janus Kinase 3; Killer Cells, Natural; Mutation; Peptide Biosynthesis; Peptides; Phenylalanine; Phosphorylation; Precipitin Tests; Proline; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Interleukin-2; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; T-Lymphocytes; Transfection; Tyrosine | 2002 |
Phenylalanine hydroxylase mutations and phenylalanine-tyrosine metabolism in heterozygotes for phenylalanine hydroxylase deficiency.
Topics: Adult; Biomarkers; Case-Control Studies; Female; Heterozygote; Humans; Italy; Male; Matched-Pair Analysis; Middle Aged; Mutation; Phenylalanine; Phenylketonurias; Statistics, Nonparametric; Tyrosine | 2002 |
Molecular analysis of tyrosine-and phenylalanine-mediated repression of the tyrB promoter by the TyrR protein of Escherichia coli.
Topics: Base Sequence; DNA Footprinting; DNA-Directed RNA Polymerases; DNA, Bacterial; Escherichia coli; Escherichia coli Proteins; Genes, Bacterial; Molecular Sequence Data; Mutation; Phenylalanine; Promoter Regions, Genetic; Regulon; Repressor Proteins; Tyrosine | 2002 |
In vivo production of hydroxyl radical by Enterococcus faecalis colonizing the intestinal tract using aromatic hydroxylation.
Topics: Animals; Chromatography, High Pressure Liquid; Colon; Electron Spin Resonance Spectroscopy; Enterococcus faecalis; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Intestines; Nitrobenzenes; Nitrogen Oxides; Oxidative Stress; Phenylalanine; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2002 |
8-Oxoguanine rearranges the active site of human topoisomerase I.
Topics: Base Sequence; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Topoisomerases, Type I; Enzyme Stability; Guanine; Humans; In Vitro Techniques; Models, Molecular; Phenylalanine; Protein Conformation; Recombinant Proteins; Static Electricity; Tyrosine | 2002 |
Aromatic side-chain interactions in proteins. I. Main structural features.
Topics: Amino Acids, Aromatic; Animals; Histidine; Molecular Structure; Phenylalanine; Protein Structure, Secondary; Proteins; Sequence Analysis, Protein; Tryptophan; Tyrosine | 2002 |
Aromatic side-chain interactions in proteins. II. Near- and far-sequence Phe-X pairs.
Topics: Amino Acids, Aromatic; Animals; Histidine; Models, Molecular; Molecular Structure; Phenylalanine; Protein Folding; Protein Structure, Secondary; Proteins; Sequence Analysis, Protein; Tryptophan; Tyrosine | 2002 |
[Rapid high performance liquid chromatography for determination of phenylalanine and tyrosine in serum].
Topics: Adult; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Reference Values; Tyrosine | 2000 |
Tuning of the redox potential of the primary electron donor in reaction centres of purple bacteria: effects of amino acid polarity and position.
Topics: Amino Acids; Electrons; Histidine; Leucine; Models, Molecular; Oxidation-Reduction; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Point Mutation; Protein Conformation; Rhodobacter sphaeroides; Tyrosine | 2002 |
Cloning and characterization of an aromatic amino acid and leucine permease of Penicillium chrysogenum.
Topics: Amino Acid Sequence; Amino Acid Transport Systems; Base Sequence; Cloning, Molecular; DNA, Complementary; Leucine; Molecular Sequence Data; Penicillium chrysogenum; Phenylalanine; Saccharomyces cerevisiae; Sequence Alignment; Tryptophan; Tyrosine | 2002 |
Single amino acid substitution in Bacillus sphaericus phenylalanine dehydrogenase dramatically increases its discrimination between phenylalanine and tyrosine substrates.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acid Sequence; Amino Acid Substitution; Bacillus; Base Sequence; Binding Sites; DNA Primers; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phenylalanine; Protein Conformation; Recombinant Proteins; Restriction Mapping; Sequence Alignment; Substrate Specificity; Tyrosine | 2002 |
Validation of the phenylalanine/tyrosine ratio determined by tandem mass spectrometry: sensitive newborn screening for phenylketonuria.
Topics: Blood Specimen Collection; Chromatography, Ion Exchange; Fluorometry; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2002 |
Regulation of actin dynamics by tyrosine phosphorylation: identification of tyrosine phosphorylation sites within the actin-severing domain of villin.
Topics: Actins; Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins; CSK Tyrosine-Protein Kinase; Genetic Vectors; Humans; Microfilament Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Phosphorylation; Polymers; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Sequence Deletion; src-Family Kinases; Substrate Specificity; Thermodynamics; Transfection; Tyrosine | 2002 |
Heteromultimerization modulates P2X receptor functions through participating extracellular and C-terminal subdomains.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Apyrase; Azides; Biotinylation; Calcium; Cell Line; Cell Membrane; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Epitopes; Ions; Isoleucine; Kinetics; Ligands; Mice; Mutation; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Purinergic P2; Receptors, Purinergic P2X2; Receptors, Purinergic P2X3; Signal Transduction; Time Factors; Transfection; Tyrosine; Valine; Xenopus laevis | 2002 |
Biochemical characterization and structural analysis of a highly proficient cocaine esterase.
Topics: Bacterial Proteins; Binding Sites; Binding Sites, Antibody; Carboxylic Ester Hydrolases; Catalysis; Catalytic Domain; Cocaine; Crystallization; Crystallography, X-Ray; Hydrogen-Ion Concentration; Hydrolysis; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Rhodococcus; Structure-Activity Relationship; Substrate Specificity; Tyrosine; Urea | 2002 |
Mutations in the putative pore-forming segment favor short-lived wild-type Kir2.1 pore conformations.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Cysteine; Glycosylation; Ion Channel Gating; Isoleucine; Mice; Molecular Sequence Data; Patch-Clamp Techniques; Peptide Fragments; Phenylalanine; Point Mutation; Potassium Channels, Inwardly Rectifying; Protein Conformation; Protein Structure, Tertiary; Serine; Spodoptera; Threonine; Time Factors; Tyrosine | 2002 |
Inhibition of autophagic proteolysis by inhibitors of phosphoinositide 3-kinase can interfere with the regulation of glycogen synthesis in isolated hepatocytes.
Topics: Adenosine Triphosphate; Amides; Androstadienes; Animals; Autophagy; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose; Glycogen; Hepatocytes; Imidazoles; Indoles; Insulin; Lactic Acid; Leucine; Male; Morpholines; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Rats; Rats, Wistar; Tyrosine; Wortmannin | 2002 |
Study of second-site suppression in the pheP gene for the phenylalanine transporter of Escherichia coli.
Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Bacterial Proteins; Consensus Sequence; Escherichia coli; Escherichia coli Proteins; GABA Plasma Membrane Transport Proteins; Genes, Bacterial; Glutamic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Organic Anion Transporters; Phenylalanine; Proline; Tyrosine | 2002 |
Somatotropin-induced protein anabolism in hindquarters and portal-drained viscera of growing pigs.
Topics: Animals; Body Weight; Carbon Isotopes; Female; Growth Hormone; Hindlimb; Intestine, Small; Models, Biological; Muscle, Skeletal; Phenylalanine; Portal System; Protein Biosynthesis; Swine; Tritium; Tyrosine; Viscera | 2003 |
Stabilizing interactions between aromatic and basic side chains in alpha-helical peptides and proteins. Tyrosine effects on helix circular dichroism.
Topics: Amino Acid Sequence; Arginine; Circular Dichroism; Crystallography, X-Ray; Lysine; Models, Chemical; Models, Molecular; Molecular Sequence Data; Oligopeptides; Phenylalanine; Protein Structure, Secondary; Tyrosine | 2002 |
Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.
Topics: Amino Acids, Aromatic; Animals; Bacteria; Chromatography, High Pressure Liquid; Eukaryota; Goats; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rumen; Tyrosine | 2002 |
Gas chromatography-mass spectrometry method for determination of phenylalanine and tyrosine in neonatal blood spots.
Topics: Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Reproducibility of Results; Tyrosine | 2002 |
Process control for enhanced L-phenylalanine production using different recombinant Escherichia coli strains.
Topics: Bioreactors; Cells, Cultured; Escherichia coli; Feedback; Glucose; Homeostasis; Phenylalanine; Pilot Projects; Quality Control; Recombinant Proteins; Recombination, Genetic; Reproducibility of Results; Sensitivity and Specificity; Species Specificity; Tyrosine | 2002 |
Calcium binding to calmodulin mutants monitored by domain-specific intrinsic phenylalanine and tyrosine fluorescence.
Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Ligands; Models, Molecular; Molecular Sequence Data; Mutation; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Rats; Spectrometry, Fluorescence; Thermodynamics; Time Factors; Tyrosine | 2002 |
Plasma amino acid concentrations in healthy and cognitively impaired oldest-old individuals: associations with anthropometric parameters of body composition and functional disability.
Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Analysis of Variance; Body Composition; Body Mass Index; Case-Control Studies; Chi-Square Distribution; Creatinine; Disabled Persons; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Phenylalanine; Tyrosine | 2002 |
Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.
Topics: Amino Acid Substitution; Animals; Apoptosis; B-Lymphocyte Subsets; B-Lymphocytes; Cell Division; Cell Line, Tumor; Cell Survival; Cyclin D1; Enzyme Activation; Enzyme Precursors; Gene Expression Regulation, Enzymologic; Intracellular Signaling Peptides and Proteins; Lymphoma, B-Cell; Mice; Mutation; Phenylalanine; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; Syk Kinase; Tyrosine | 2002 |
Local protein dynamics and catalysis: detection of segmental motion associated with rate-limiting product release by a glutathione transferase.
Topics: Amides; Amino Acid Substitution; Animals; Catalysis; Circular Dichroism; Crystallization; Crystallography, X-Ray; Deuterium Oxide; Dinitrochlorobenzene; Glutathione Transferase; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Rats; Spectrometry, Fluorescence; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Tyrosine | 2002 |
Engineering-specific pharmacological binding sites for peptidyl inhibitors of potassium channels into KcsA.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Bacterial Proteins; Binding Sites; Delayed Rectifier Potassium Channels; Humans; Kv1.1 Potassium Channel; Kv1.2 Potassium Channel; Kv1.3 Potassium Channel; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Structure, Tertiary; Recombinant Fusion Proteins; Scorpion Venoms; Surface Plasmon Resonance; Tyrosine | 2002 |
Synthesis of no-carrier-added C-11 labeled D- and L-enantiomers of phenylalanine and tyrosine for comparative PET Studies.
Topics: Carbon Radioisotopes; Isotope Labeling; Phenylalanine; Radiopharmaceuticals; Stereoisomerism; Tomography, Emission-Computed; Tyrosine | 2003 |
Replacement of tyrosine D with phenylalanine affects the normal proton transfer pathways for the reduction of P680+ in oxygen-evolving photosystem II particles from Chlamydomonas.
Topics: Algal Proteins; Amino Acid Substitution; Animals; Chlamydomonas reinhardtii; Electron Spin Resonance Spectroscopy; Energy Transfer; Free Radicals; Kinetics; Mutagenesis, Insertional; Oxidation-Reduction; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Photosystem II Protein Complex; Plant Proteins; Protons; Spinacia oleracea; Static Electricity; Tyrosine | 2002 |
Site-directed mutagenesis of dimethyl sulfoxide reductase from Rhodobacter capsulatus: characterization of a Y114 --> F mutant.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Dimethyl Sulfoxide; Electrochemistry; Hydrogen-Ion Concentration; Iron-Sulfur Proteins; Kinetics; Molybdenum; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Phenylalanine; Protein Binding; Recombinant Proteins; Rhodobacter capsulatus; Spectrophotometry, Ultraviolet; Tyrosine | 2002 |
Biotin sulfoxide reductase: Tryptophan 90 is required for efficient substrate utilization.
Topics: Alanine; Escherichia coli; Guanine Nucleotides; Iron-Sulfur Proteins; Isoenzymes; Molybdenum; Mutagenesis, Site-Directed; Oxidoreductases; Phenylalanine; Pterins; Recombinant Fusion Proteins; Rhodobacter sphaeroides; Tryptophan; Tyrosine | 2003 |
Biosynthetically directed fractional 13C labeling facilitates identification of Phe and Tyr aromatic signals in proteins.
Topics: Amino Acids, Aromatic; Carbon Isotopes; Humans; Hydrogen Bonding; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Peptide Mapping; Phenylalanine; Proteins; Staining and Labeling; Tyrosine | 2002 |
Distinct sites regulating grayanotoxin binding and unbinding to D4S6 of Na(v)1.4 sodium channel as revealed by improved estimation of toxin sensitivity.
Topics: Amino Acid Sequence; Animals; Asparagine; Binding Sites; Cell Membrane; Cloning, Molecular; Diterpenes; DNA, Complementary; Electrophysiology; Kinetics; Models, Chemical; Molecular Sequence Data; Muscle Proteins; Mutagenesis, Site-Directed; Mutation; NAV1.5 Voltage-Gated Sodium Channel; Phenylalanine; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rats; Serine; Sodium Channels; Transfection; Tyrosine | 2003 |
Aromatic residues at the extracellular ends of transmembrane domains 5 and 6 promote ligand activation of the G protein-coupled alpha-factor receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Extracellular Space; GTP-Binding Proteins; Ligands; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Novobiocin; Phenotype; Phenylalanine; Protein Structure, Tertiary; Receptors, Cell Surface; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Transcription Factors; Tyrosine | 2003 |
Development of intramolecularly quenched fluorescent peptides as substrates of angiotensin-converting enzyme 2.
Topics: Angiotensin-Converting Enzyme 2; Carboxypeptidases; Enzyme Inhibitors; Fluorescence; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Myocardium; Nitric Oxide; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Substrate Specificity; Tyrosine | 2003 |
Aromatic stacking in the sugar binding site of the lactose permease.
Topics: Alkylation; Amino Acids, Aromatic; Binding Sites; Biological Transport, Active; Cysteine; Escherichia coli Proteins; Ethylmaleimide; Kinetics; Lactose; Membrane Transport Proteins; Monosaccharide Transport Proteins; Nitrophenylgalactosides; Phenylalanine; Substrate Specificity; Symporters; Thiogalactosides; Tryptophan; Tyrosine | 2003 |
Molecular dissection of a quantitative trait locus: a phenylalanine-to-tyrosine substitution in the transmembrane domain of the bovine growth hormone receptor is associated with a major effect on milk yield and composition.
Topics: Amino Acid Substitution; Animals; Cattle; Chromosome Mapping; Haplotypes; Linkage Disequilibrium; Lod Score; Microsatellite Repeats; Milk; Phenylalanine; Phylogeny; Polymorphism, Genetic; Quantitative Trait Loci; Receptors, Somatotropin; Tyrosine | 2003 |
Measuring whole-body actin/myosin protein breakdown in mice using a primed constant stable isotope-infusion protocol.
Topics: Actins; Animals; Body Weight; Chromatography, Liquid; Deuterium; Infusions, Intravenous; Lipopolysaccharides; Male; Mass Spectrometry; Methylhistidines; Mice; Mice, Inbred Strains; Models, Animal; Muscles; Myosins; Phenylalanine; Radioactive Tracers; Starvation; Tyrosine | 2003 |
Oxygen and hydrogen isotope effects in an active site tyrosine to phenylalanine mutant of peptidylglycine alpha-hydroxylating monooxygenase: mechanistic implications.
Topics: Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Catalysis; Cell Line; Deuterium; Dopamine beta-Hydroxylase; Hippurates; Humans; Hydroxylation; Kinetics; Mixed Function Oxygenases; Multienzyme Complexes; Oxygen Isotopes; Phenylalanine; Tyrosine | 2003 |
B-side charge separation in bacterial photosynthetic reaction centers: nanosecond time scale electron transfer from HB- to QB.
Topics: Bacteriochlorophylls; Benzoquinones; Dimerization; Electron Transport; Histidine; Imidoesters; Kinetics; Light-Harvesting Protein Complexes; Mutation; Nanotechnology; Phenylalanine; Pheophytins; Photolysis; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Static Electricity; Triazines; Tyrosine | 2003 |
Spectroscopic characterization of five- and six-coordinate ferrous-NO heme complexes. Evidence for heme Fe-proximal cysteinate bond cleavage in the ferrous-NO adducts of the Trp-409Tyr/Phe proximal environment mutants of neuronal nitric oxide synthase.
Topics: Circular Dichroism; Cysteine; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Humans; Iron-Sulfur Proteins; Ligands; Mutagenesis, Site-Directed; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Phenylalanine; Protein Structure, Tertiary; Solvents; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 2003 |
Modification of the N-terminus of peptidomimetic protein tyrosine phosphatase 1B (PTP1B) inhibitors: identification of analogues with cellular activity.
Topics: Animals; Cells, Cultured; Deoxyglucose; Enzyme Inhibitors; Humans; Insulin; Molecular Mimicry; Muscle, Skeletal; Phenylalanine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Salicylates; src Homology Domains; Tyrosine | 2003 |
Modeled ligand-protein complexes elucidate the origin of substrate specificity and provide insight into catalytic mechanisms of phenylalanine hydroxylase and tyrosine hydroxylase.
Topics: Amino Acid Sequence; Animals; Biopterins; Catalytic Domain; Dopamine; Humans; Levodopa; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Phenylalanine; Phenylalanine Hydroxylase; Protein Binding; Rats; Sequence Alignment; Substrate Specificity; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
Simultaneous measurement of phenylalanine and tyrosine in phenylketonuric plasma and dried blood by high-performance liquid chromatography.
Topics: Animals; Calibration; Chromatography, High Pressure Liquid; Female; Phenylalanine; Phenylketonurias; Pregnancy; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tyrosine | 2003 |
Tyrosine phosphorylation of I-kappa B kinase alpha/beta by protein kinase C-dependent c-Src activation is involved in TNF-alpha-induced cyclooxygenase-2 expression.
Topics: Amino Acid Sequence; Amino Acid Substitution; CSK Tyrosine-Protein Kinase; Cyclooxygenase 2; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans; I-kappa B Kinase; Isoenzymes; Membrane Proteins; Molecular Sequence Data; NF-kappa B; Phenylalanine; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyrimidines; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Plasma amino acid levels in children with autism and their families.
Topics: Adolescent; Alanine; Amino Acids; Asparagine; Asperger Syndrome; Autistic Disorder; Brain Diseases, Metabolic, Inborn; Child; Child, Preschool; Family; Female; Glutamic Acid; Glutamine; Humans; Lysine; Male; Phenylalanine; Tyrosine | 2003 |
A novel amphibian Pi-class glutathione transferase isoenzyme from Xenopus laevis: importance of phenylalanine 111 in the H-site.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Dinitrochlorobenzene; Escherichia coli; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Glutathione S-Transferase pi; Glutathione Transferase; Glycine; Humans; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Substrate Specificity; Tyrosine; Xenopus laevis; Xenopus Proteins | 2003 |
The total branched-chain amino acid requirement in young healthy adult men determined by indicator amino acid oxidation by use of L-[1-13C]phenylalanine.
Topics: Amino Acids, Branched-Chain; Body Composition; Carbon Isotopes; Energy Intake; Humans; Isoleucine; Isotope Labeling; Leucine; Male; Nitrogen; Nutritional Requirements; Phenylalanine; Tyrosine; Valine | 2003 |
A transthyretin mutation (Tyr78Phe) associated with peripheral neuropathy, carpal tunnel syndrome and skin amyloidosis.
Topics: Aged; Amyloidosis; Base Sequence; Carpal Tunnel Syndrome; Humans; Male; Pedigree; Peripheral Nervous System Diseases; Phenylalanine; Point Mutation; Polymorphism, Single-Stranded Conformational; Prealbumin; Skin; Tyrosine | 2003 |
Requirement of tryptophan in relation to the supply of large neutral amino acids in laying hens.
Topics: Amino Acids, Neutral; Animal Nutritional Physiological Phenomena; Animals; Chickens; Dose-Response Relationship, Drug; Female; Isoleucine; Leucine; Nutritional Requirements; Oviposition; Phenylalanine; Regression Analysis; Tryptophan; Tyrosine; Valine; Weight Gain | 2003 |
A new strategy for the site-specific modification of proteins in vivo.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Outer Membrane Proteins; Cell Line; DNA Primers; Escherichia coli; Fluoresceins; Gene Expression Regulation, Bacterial; Genes, Bacterial; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Tertiary; Recombinant Proteins; RNA, Transfer; Spectrometry, Fluorescence; Staining and Labeling; Tyrosine | 2003 |
Growth conditions, elemental accumulation and induced physiological changes in Chinese cabbage.
Topics: Agriculture; Aluminum; Anthocyanins; Boron; Brassica; Calcium; Catechol Oxidase; Pectins; Phenols; Phenylalanine; Silicon; Silver; Soil; Soil Pollutants; Trace Elements; Tyrosine; Water | 2003 |
Conserved hydrophobicity in the SH2-kinase linker is required for catalytic activity of Csk and CHK.
Topics: Alanine; Amino Acid Sequence; Animals; Blotting, Western; Catalysis; Catalytic Domain; COS Cells; Crystallography, X-Ray; CSK Tyrosine-Protein Kinase; Gene Deletion; HeLa Cells; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Plasmids; Point Mutation; Precipitin Tests; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); src Homology Domains; src-Family Kinases; Transfection; Tyrosine; Valine | 2003 |
Specific amino acid dependency regulates invasiveness and viability of androgen-independent prostate cancer cells.
Topics: Amino Acids; Androgens; Animals; Apoptosis; Cell Adhesion; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Fragmentation; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Male; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Phenylalanine; Phosphorylation; Prostatic Neoplasms; Protein-Tyrosine Kinases; Tyrosine | 2003 |
Catabolism of aromatic amino acids in cheese-related bacteria: aminotransferase and decarboxylase activities.
Topics: Amino Acids, Aromatic; Bacteria; Brevibacterium; Carboxy-Lyases; Cheese; Corynebacterium; Lacticaseibacillus casei; Lactobacillus; Phenylalanine; Transaminases; Tryptophan; Tyrosine | 2003 |
TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
Topics: 3T3 Cells; Amino Acid Substitution; Animals; Antigens, CD; Cell Line; Cytokine Receptor gp130; DNA-Binding Proteins; Enzyme Activation; Interleukin-6; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phosphorylation; Protein Phosphatase 2; Protein Subunits; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Interleukin-6; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; STAT3 Transcription Factor; Trans-Activators; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Characterization of tryptophan high affinity transport system in pinealocytes of the rat. Day-night modulation.
Topics: Animals; Biological Transport; Circadian Rhythm; Enzyme Inhibitors; Ethylmaleimide; Hydrogen-Ion Concentration; Male; Osmolar Concentration; Phenylalanine; Photoperiod; Pineal Gland; Rats; Rats, Sprague-Dawley; Temperature; Tryptophan; Tyrosine | 2003 |
Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652.
Topics: Amino Acid Substitution; Cation Transport Proteins; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluvoxamine; Humans; Membrane Potentials; Mutation; Phenylalanine; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Trans-Activators; Transcriptional Regulator ERG; Tyrosine | 2003 |
Active stromelysin-3 (MMP-11) increases MCF-7 survival in three-dimensional Matrigel culture via activation of p42/p44 MAP-kinase.
Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Caspase Inhibitors; Cell Survival; Collagen; Drug Combinations; Enzyme Activation; Enzyme Inhibitors; Female; Humans; In Situ Nick-End Labeling; Laminin; Matrix Metalloproteinase 11; Metalloendopeptidases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphorylation; Protein Serine-Threonine Kinases; Proteoglycans; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Thiophenes; Transfection; Tumor Cells, Cultured; Tyrosine | 2003 |
T cell antagonism is functionally uncoupled from the 21- and 23-kDa tyrosine-phosphorylated TCR zeta subunits.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Cell Differentiation; Cell Line; Cell Membrane; Down-Regulation; Lymphocyte Activation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Weight; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Subunits; Receptors, Antigen, T-Cell; Receptors, Antigen, T-Cell, alpha-beta; T-Lymphocyte Subsets; Tyrosine | 2003 |
Region and amino acid residues required for Rad51C binding in the human Xrcc3 protein.
Topics: Amino Acid Sequence; Amino Acids; Binding Sites; DNA-Binding Proteins; Humans; Molecular Sequence Data; Mutation; Phenylalanine; Protein Binding; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Two-Hybrid System Techniques; Tyrosine | 2003 |
Phenylalanine kinetics in cirrhosis.
Topics: Carbon Isotopes; Humans; Kinetics; Liver Cirrhosis; Phenylalanine; Tyrosine | 2003 |
Relationship between myelin production and dopamine synthesis in the PKU mouse brain.
Topics: Animals; Blotting, Western; Brain; Brain Chemistry; Corpus Striatum; Disease Models, Animal; Dopamine; Food, Formulated; Frontal Lobe; Male; Mice; Mice, Mutant Strains; Myelin Basic Protein; Myelin Sheath; Neurofilament Proteins; Phenylalanine; Phenylketonurias; Phosphorylation; Tyrosine; Tyrosine 3-Monooxygenase | 2003 |
Inhibition of proteasome activity by selected amino acids.
Topics: Amino Acids; Animals; Arginine; Cysteine Endopeptidases; Enzyme Inhibitors; Insulin; Isoleucine; Leucine; Liver; Lysine; Lysosomes; Male; Multienzyme Complexes; Muscle, Skeletal; Phenylalanine; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine | 2003 |
Role of acidic and aromatic amino acids in Rhodobacter capsulatus cytochrome c1. A site-directed mutagenesis study.
Topics: Amino Acids; Animals; Cattle; Chickens; Cytochromes c1; Electron Spin Resonance Spectroscopy; Heme; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photosynthesis; Protein Binding; Rhodobacter capsulatus; Tyrosine; Yeasts | 2003 |
Identification and characterization of signal transducer and activator of transcription 3 recruitment sites within the epidermal growth factor receptor.
Topics: 3T3 Cells; Animals; Biosensing Techniques; Carcinoma, Squamous Cell; Cell Division; DNA-Binding Proteins; DNA, Neoplasm; ErbB Receptors; Humans; Kinetics; Mice; Mutation; Peptide Mapping; Phenylalanine; Phosphopeptides; Protein Binding; STAT3 Transcription Factor; Trans-Activators; Transfection; Tumor Cells, Cultured; Tyrosine | 2003 |
Spectral variants of green fluorescent protein.
Topics: Green Fluorescent Proteins; Histidine; Hydrogen-Ion Concentration; Ions; Light; Luminescent Proteins; Models, Chemical; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Structure, Quaternary; Temperature; Tryptophan; Tyrosine | 1999 |
A novel method for the biosynthesis of deuterated proteins with selective protonation at the aromatic rings of Phe, Tyr and Trp.
Topics: Bacterial Proteins; Deuterium; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proteins; Protons; Shikimic Acid; Tryptophan; Tyrosine | 2003 |
A new class of mutations reveals a novel function for the original phosphatidylinositol 3-kinase binding site.
Topics: Alanine; Alleles; Amino Acid Sequence; Animals; Binding Sites; Immunoblotting; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mutation; Phenylalanine; Phosphatidylinositol 3-Kinases; Plasmids; Precipitin Tests; Protein Binding; Retroviridae; src Homology Domains; Tyrosine | 2003 |
Differentiation of natural and synthetic phenylalanine and tyrosine through natural abundance 2H nuclear magnetic resonance.
Topics: Animals; Animals, Genetically Modified; Benzoates; Deuterium; Magnetic Resonance Spectroscopy; Phenylalanine; Phenylethyl Alcohol; Tyrosine | 2003 |
[Quantum chemistry study on fluorescence spectra of three kinds of amino acids].
Topics: Phenylalanine; Quantum Theory; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2003 |
[Simultaneous determination of tryptophan, tyrosine and phenylalanine in injection by derivative fluorescent PLS method].
Topics: Injections; Phenylalanine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2001 |
Role of mutation Y6F on the binding properties of Schistosoma japonicum glutathione S-transferase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Calorimetry; Glutathione Transferase; Kinetics; Phenylalanine; Protein Binding; Protein Folding; Schistosoma japonicum; Temperature; Thermodynamics; Tyrosine; Urea | 2003 |
Thermodynamics of glutathione binding to the tyrosine 7 to phenylalanine mutant of glutathione S-transferase from Schistosoma japonicum.
Topics: Amino Acid Substitution; Animals; Binding Sites; Calorimetry; Glutathione; Glutathione Transferase; Hydrogen Bonding; Models, Molecular; Phenylalanine; Protein Binding; Protein Conformation; Schistosoma japonicum; Solvents; Static Electricity; Temperature; Thermodynamics; Titrimetry; Tyrosine | 2003 |
Nutrient intakes and physical growth of children with phenylketonuria undergoing nutrition therapy.
Topics: Body Height; Body Weight; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Dietary Proteins; Eating; Energy Intake; Female; Food, Formulated; Growth; Humans; Longitudinal Studies; Male; Nutrition Policy; Nutritional Requirements; Obesity; Phenylalanine; Phenylketonurias; Tyrosine; United States | 2003 |
Effects of high-voltage cathode rays on aqueous solutions of tryptophan, tyrosine, phenylalanine and cystine.
Topics: Amino Acids; Beta Particles; Cathode Ray Tube; Cystine; Phenylalanine; Tryptophan; Tyrosine | 1952 |
Utilization of glucose-1-C14 for the synthesis of phenylalanine and tyrosine.
Topics: Carbohydrate Metabolism; Glucose; Phenylalanine; Saccharomyces cerevisiae; Tyrosine; Yeasts | 1952 |
Metabolism of phenylalanine and tyrosine.
Topics: Acetoacetates; Acids; Biochemical Phenomena; Epinephrine; Norepinephrine; Phenylalanine; Proteins; Thyroxine; Tyrosine | 1953 |
Pigment formation by Bacterium salmonicida.
Topics: Bacteria; Biological Products; Phenylalanine; Pigments, Biological; Tyrosine | 1953 |
Phenylalanine and tyrosine metabolism in patients with phenylketonuria.
Topics: Humans; Ketones; Phenylalanine; Phenylketonurias; Tyrosine; Urine | 1953 |
[The presence and determination of some free amino acids containing a benzene or an indole nucleus in human nasal secretions].
Topics: Amino Acids; Benzene; Humans; Indoles; Nasal Cavity; Paranasal Sinuses; Phenylalanine; Tryptophan; Tyrosine | 1953 |
Action of proteinases on gamma-glutamylamino acid amides and carbonylbisamino acid amides.
Topics: Amides; Arginine; Endopeptidases; Glycine; Hydrolases; Peptide Hydrolases; Phenylalanine; Tyrosine | 1954 |
Phenylalanine and tyrosine utilization in normal and phenylalanine-deficient young mice.
Topics: Animals; Mice; Phenylalanine; Tyrosine | 1954 |
Metabolism of phenylalanine and tyrosine by Escherichia coli strain K-12.
Topics: Escherichia coli; Phenylalanine; Serine; Tyrosine | 1954 |
Destruction of phenylalanine and tyrosine during the anodic oxidation of C-terminal residues in acyl peptides.
Topics: Oxidation-Reduction; Peptides; Phenylalanine; Tyrosine | 1954 |
[Relation of globular proteins to phenylalanine and tyrosine esters].
Topics: Albumins; Esters; Phenylalanine; Tyrosine | 1954 |
Amino acid composition and electrophoretic properties of hypertensin I.
Topics: Amino Acids; Angiotensin Amide; Angiotensins; Arginine; Aspartic Acid; Glycine; Histidine; Isoleucine; Leucine; Phenylalanine; Proline; Serine; Tyrosine; Valine | 1955 |
The effects of tyrosine and phenylalanine on the synthesis of pigment in melanocytes of embryonic chick skin cultured in vitro.
Topics: Animals; Biological Products; Chickens; In Vitro Techniques; Melanocytes; Phenylalanine; Pigments, Biological; Research Design; Skin; Tissue Culture Techniques; Tyrosine | 1955 |
The amino acid requirements of man. XIV. The sparing effect of tyrosine on the phenylalanine requirement.
Topics: Humans; Male; Phenylalanine; Tyrosine | 1955 |
Metabolism of the aromatic amino acids.
Topics: Amino Acids, Aromatic; Biochemical Phenomena; Phenylalanine; Tryptophan; Tyrosine | 1955 |
Phenylalanine as an amino acid antagonist for the rat.
Topics: Amino Acids; Animals; Methionine; Phenylalanine; Rats; Threonine; Tryptophan; Tyrosine | 1956 |
Inhibition of phenylalanine and tyrosine synthesis on Streptococcus faecalis and Lactobacillus arabinosus by alpha-keto acids.
Topics: Biochemical Phenomena; Enterococcus faecalis; Keto Acids; Ketones; Lactobacillus; Lactobacillus plantarum; Phenylalanine; Streptococcus; Tyrosine | 1956 |
[Mechanism of action of ultrasonics. I. Oxidation of aromatic compounds].
Topics: Amphetamine; Amphetamines; Benzene; Benzene Derivatives; Biochemical Phenomena; Oxidation-Reduction; Phenylalanine; Tryptophan; Tyrosine; Ultrasonics | 1955 |
The quantitative amino acid requirements of young women. IV. Phenylalanine, with and without tyrosine.
Topics: Female; Humans; Phenylalanine; Tyrosine | 1956 |
[Some experiments on phenylalanine- and tyrosine metabolism in a patient with phenylpyruvic oligophrenia].
Topics: Biochemical Phenomena; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1956 |
Conversion of phenylalanine into tyrosine in the silkworm larva (Bombyx mori).
Topics: Animals; Biochemical Phenomena; Bombyx; Larva; Moths; Phenylalanine; Tyrosine | 1956 |
Comparison of the metabolism of uniformly 14C-labelled L-phenylalanine, L-tyrosine and L-tryptophan in the rat.
Topics: Animals; Phenylalanine; Rats; Tryptophan; Tyrosine | 1956 |
Precursors of adrenal epinephrine and norepinephrine in vivo.
Topics: Dihydroxyphenylalanine; Epinephrine; Norepinephrine; Phenylalanine; Tyrosine | 1956 |
Competitive inhibition of mammalian tyrosinase by phenylalanine and its relationship to hair pigmentation in phenylketonuria.
Topics: Animals; Hair; Humans; Intellectual Disability; Monophenol Monooxygenase; Phenylalanine; Phenylketonurias; Pigmentation; Tyrosine | 1957 |
The enzymic conversion of phenylalanine to tyrosine.
Topics: Biochemical Phenomena; Humans; Liver; Phenylalanine; Tyrosine | 1957 |
[Investigations of phenylalanine and tyrosine metabolism in a child with phenylpyruvic oligophrenia].
Topics: Biochemical Phenomena; Humans; Intellectual Disability; Oxidoreductases; Phenylalanine; Phenylketonurias; Tyrosine | 1956 |
Some investigations on the metabolism of phenylalanine and tyrosine in children with vitamin C deficiency.
Topics: Amino Acids; Ascorbic Acid Deficiency; Child; Humans; Infant; Phenylalanine; Scurvy; Tyrosine | 1957 |
The enzymatic conversion of phenylalanine to tyrosine.
Topics: Humans; Liver; Phenylalanine; Tyrosine | 1957 |
Phenylalanine inhibition of tyrosine metabolism in the liver.
Topics: Animals; Biochemical Phenomena; Insecta; Liver; Phenylalanine; Tyrosine | 1957 |
Studies on conversion of phenylalanine to tyrosine in phenylpyruvic oligophrenia.
Topics: Biochemical Phenomena; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1957 |
The nutrition of animal tissues cultivated in vitro. IV. Amino acid requirements of chick embryonic heart fibroblasts.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Chickens; Cystine; Fibroblasts; Glycine; Histidine; Hydroxyproline; In Vitro Techniques; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
The phenylalanine and tyrosine requirement of the growing chick with special reference to the utilization of the D-isomer of phenylalanine.
Topics: Animals; Chickens; Humans; Isomerism; Meat; Phenylalanine; Poultry; Tyrosine | 1957 |
[Studies on phenylalanine & tyrosine metabolism in scurvy in children].
Topics: Biochemical Phenomena; Child; Humans; Infant; Phenylalanine; Scurvy; Tyrosine | 1957 |
[Oxidation of tyrosine, thyronine, and their iodo derivatives. I. Actions of the ascorbic acid-ferrous ion-oxygen system].
Topics: Ascorbic Acid; Iron, Dietary; Oxidation-Reduction; Oxygen; Phenylalanine; Thyronines; Tyrosine | 1957 |
The amino acid requirements of rabbit fibroblasts, strain RM3-56.
Topics: Alanine; Amino Acids; Animals; Arginine; Cystine; Fibroblasts; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Rabbits; Serine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Valine | 1957 |
Phenylalanine and tyrosine metabolism in E. coli strain K-12.
Topics: Biochemical Phenomena; Escherichia coli; Phenylalanine; Tyrosine | 1957 |
The effects of growth hormone on phenylalanine-tyrosine deficient and pair-fed rats.
Topics: Animals; Body Weight; Body Weights and Measures; Growth; Growth Hormone; Human Growth Hormone; Phenylalanine; Rats; Tyrosine | 1957 |
The utilization of phenylalanine and tyrosine for protein synthesis by human cells in tissue culture.
Topics: Humans; Learning; Phenylalanine; Protein Biosynthesis; Proteins; Tyrosine | 1957 |
A note on the effect of cold and vitamin C on the blood levels of phenylalanine and tyrosine in rats.
Topics: Animals; Ascorbic Acid; Cold Temperature; Phenylalanine; Rats; Tyrosine; Vitamins | 1958 |
Intermediary metabolism of phenylalanine and tyrosine in diffuse collagen diseases. I. The presence of 2,5-dihydroxyphenylpyruvic acid in the urine of patients with collagen disease.
Topics: Biochemical Phenomena; Body Fluids; Collagen Diseases; Health Services; Humans; Phenylalanine; Pyruvates; Tyrosine | 1958 |
The participation of tetra-hydrofolic acid in the enzymic conversion of phenylalanine to tyrosine.
Topics: Animals; Biochemical Phenomena; Characidae; Coenzymes; Folic Acid; Phenylalanine; Tetracycline; Tyrosine | 1958 |
A new cofactor required for the enzymatic conversion of phenylalanine to tyrosine.
Topics: Coenzymes; Humans; Liver; Organic Chemicals; Phenylalanine; Tyrosine | 1958 |
Disorders associated with the metabolism of phenylalanine and tyrosine.
Topics: Humans; Phenylalanine; Tyrosine | 1958 |
The metabolism of aromatic amino acids in leukemic rats.
Topics: Amino Acids, Aromatic; Animals; Leukemia; Phenylalanine; Rats; Tryptophan; Tyrosine | 1958 |
Phenylketonuria: the phenylalanine-tyrosine ratio in the detection of the heterozygous carrier.
Topics: Biochemical Phenomena; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1958 |
[The action of a plant peroxidase on various hydroxyphenyl amino acids: tyrosine, thyronine, and certain of their iodized or hydroxylated derivatives].
Topics: Amino Acids; Coloring Agents; Hydroxylation; Oxidoreductases; Peroxidase; Peroxidases; Phenylalanine; Thyronines; Tyrosine | 1958 |
Phenylalanine hydroxylation cofactor in phenylketonuria.
Topics: Biological Assay; Hydroxylation; Phenylalanine; Phenylketonurias; Tyrosine | 1958 |
Metabolism of phenylpropanoid compounds in Salvia. I. Biosynthesis of phenylalanine and tyrosine.
Topics: Biochemical Phenomena; Phenylalanine; Plants; Salvia; Tyrosine | 1959 |
Phenylpyruvic acid as a possible precursor of o-hydroxyphenylacetic acid in man.
Topics: Administration, Oral; Humans; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1959 |
Radiation-induced formation of dihydroxyphenylalanine from tyrosine and tyrosine-containing peptides in aqueous solution.
Topics: Dihydroxyphenylalanine; Peptides; Phenylalanine; Radiation; Radiation Effects; Tyrosine | 1961 |
The control of shikimic acid synthesis by tyrosine and phenylalamine.
Topics: Phenylalanine; Shikimic Acid; Tyrosine | 1961 |
Phenylalanine and tyrosine in the adrenal medulla.
Topics: Adrenal Medulla; Biochemical Phenomena; Phenylalanine; Tyrosine | 1961 |
Phenylalanine and tyrosine in collagen diseases. Urinary excretion of general intermediary metabolites of tyrosine in patients with collagen disease and liver disease.
Topics: Collagen Diseases; Humans; Liver Diseases; Phenylalanine; Tyrosine | 1961 |
Amino acid requirements for maintenace in the adult rooster. IV. The requirements for methionine, cystine, phenylalanine, tyrosine and tryptophan; the adequacy of the determined requirements.
Topics: Amino Acids; Animals; Chickens; Cystine; Diet; Male; Methionine; Nutrition Assessment; Phenylalanine; Poultry; Tryptophan; Tyrosine | 1960 |
Further studies on the dual requirement for pheylalanine and tyrosine in tissue culture.
Topics: Biochemical Phenomena; Humans; Phenylalanine; Research Design; Tissue Culture Techniques; Tyrosine | 1961 |
Biosynthesis of phenylalanine and tyrosine in young w and buckwheat plants.
Topics: Biological Products; Fagopyrum; Phenylalanine; Plant Oils; Plants; Triticum; Tyrosine | 1959 |
Identification of heterozygotes with phenylketonuria on basis of blood tyrosine responses.
Topics: Heterozygote; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 1962 |
Two-dose phenylalanine tolerance test for detection of phenylketonuric heterozygotes. Value of tyrosine responses.
Topics: Disease; Diseases in Twins; Drug Tolerance; Heterozygote; Humans; Immune Tolerance; Phenylalanine; Phenylketonurias; Twins; Tyrosine | 1961 |
Effect of tyrosinase preparations on oxytocin, vasopressin and bradykinin.
Topics: Arginine Vasopressin; Ascorbic Acid; Bradykinin; Catechol Oxidase; Kallikreins; Monophenol Monooxygenase; Nitrophenols; Oxidoreductases; Oxytocics; Oxytocin; Phenylalanine; Tyrosine; Vasoconstrictor Agents; Vasopressins | 1962 |
Effects of L-phenylalanine and sodium phenylpyruvate on the formation of melanin from L-tyrosine in melanoma.
Topics: Melanins; Melanoma; Phenylalanine; Phenylpyruvic Acids; Sodium; Tyrosine | 1962 |
Studies on the binding of carboxypeptidase A and several competitive inhibitors.
Topics: Carboxypeptidases A; Endopeptidases; Humans; Hydrolases; Peptide Hydrolases; Phenylacetates; Phenylalanine; Propionates; Tyrosine | 1962 |
Studies on aromatic amino acid uptake by rat brain in vivo. Uptake of phenylalanine and of tryptophan; inhibition and stereoselectivity in the uptake of tyrosine by brain and muscle.
Topics: Amino Acids, Aromatic; Animals; Brain; Muscles; Neurochemistry; Phenylalanine; Rats; Tryptophan; Tyrosine | 1962 |
[The phenol and indole pattern of rat urine after administration of tyrosine, tryptophan and phenylalanine and after inhibition of the intestinal flora with neomycin].
Topics: Animals; Indoles; Intestines; Neomycin; Phenol; Phenols; Phenylalanine; Rats; Tryptophan; Tyrosine | 1962 |
[Phenylalanine hydroxylase activity in hepatomas and livers of normal and tumor-bearing animals].
Topics: Animals; Carcinoma, Hepatocellular; Enzymes; Liver; Liver Neoplasms; Neoplasms; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1961 |
Transamination and deamination of halogenated aromatic amino acids.
Topics: Amino Acids, Aromatic; Deamination; Liver; Oxidoreductases; Phenylalanine; Transaminases; Triiodothyronine; Tyrosine | 1962 |
Occurrence, isolation and identification of 3-methoxy-4-hydroxyphenylalanine.
Topics: Phenylalanine; Tyrosine | 1961 |
The problem of tyrosine metabolism in connective tissue diseases.
Topics: Connective Tissue; Connective Tissue Diseases; Humans; Phenylalanine; Tyrosine | 1962 |
Variations with age in plasma phenylalanine and tyrosine levels in phenylketonuria.
Topics: Humans; Phenylalanine; Phenylketonurias; Plasma; Tyrosine | 1963 |
Effectiveness of urea and ammonium nitrogen for the synthesis of dispensable amino acids by the chick.
Topics: Amino Acids; Ammonium Compounds; Animals; Arginine; Chickens; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Quaternary Ammonium Compounds; Threonine; Tryptophan; Tyrosine; Urea; Valine | 1962 |
[Studies on the enzymatic and genetic system in phenylalanine metabolism disorders].
Topics: Biochemical Phenomena; Enzymes; Geniculate Bodies; Humans; Intellectual Disability; Metabolic Diseases; Phenylalanine; Phenylketonurias; Tyrosine | 1962 |
Transamination of aromatic amino-acids in nervous tissue.
Topics: Amination; Amino Acids, Aromatic; Brain; Histidine; Humans; Nerve Tissue; Phenylalanine; Transaminases; Tryptophan; Tyrosine | 1962 |
Serum phenylalanine and tyrosine levels in the newborn infant.
Topics: Humans; Infant; Infant, Newborn; Phenylalanine; Tyrosine | 1962 |
Gamma irradiation of polypeptides: transformation of amino acids.
Topics: Alanine; Amino Acids; Aspartic Acid; Glutamates; Glutamic Acid; Glycine; Histidine; Methionine; Peptides; Phenylalanine; Proline; Radiation Effects; Tyrosine | 1963 |
Conversion of aromatic amino acids to fatty acids by adipose tissue.
Topics: Adipose Tissue; Amino Acids, Aromatic; Fatty Acids; Humans; Phenylalanine; Tryptophan; Tyrosine | 1963 |
[Hydroxylation of phenylalanine in animals].
Topics: Animals; Hydroxylation; Phenylalanine; Tyrosine | 1962 |
Nutrition of five Bacteroides strains.
Topics: Amino Acids; Arginine; Bacteroides; Culture Media; Fusobacterium; Glucose; Glutamic Acid; Histidine; Lysine; Phenylalanine; Purines; Tyrosine; Vitamins | 1962 |
Phenylalanine metabolism in control subjects, mental patients, and phenylketonurics.
Topics: Biochemical Phenomena; Humans; Mental Disorders; Mentally Ill Persons; Phenylalanine; Phenylketonurias; Psychotic Disorders; Tyrosine | 1962 |
Nitrogen balance studies with subjects fed the essential amino acids in plasma pattern proportions.
Topics: Amino Acids, Essential; Cystine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
Effects of folic acid on the phenylalanine tolerance test in phenylketonuria.
Topics: Antimetabolites; Child; Drug Tolerance; Folic Acid; Humans; Immune Tolerance; Phenylalanine; Phenylketonurias; Tyrosine | 1962 |
Phenylalanine requirement of women consuming a minimal tyrosine diet and the sparing effect of tyrosine on the phenylalanine requirement.
Topics: Diet; Humans; Nitrogen; Phenylalanine; Tyrosine | 1963 |
The control of 3-deoxy-D-arabino-heptulosonic acid 7-phosphate synthesis by phenylalanine and tyrosine.
Topics: Carbohydrates; Escherichia coli; Hexoses; Ligases; Phenylalanine; Phosphates; Sweetening Agents; Tyrosine | 1962 |
Repression of transaminase A by tyrosine in Escherichia coli.
Topics: Escherichia coli; Phenylalanine; Transaminases; Tyrosine | 1963 |
Occurrence of gamma-L-glutamyl-L-tyrosine and gamma-L-glutamyl-L-phenylalanine in seeds of Lupinus angustifolius and Lupinus albus.
Topics: Dipeptides; Gamma Rays; Lupinus; Phenylalanine; Seeds; Tyrosine | 1962 |
Tyrosine metabolism in insects.
Topics: Animals; Insecta; Phenylalanine; Tyrosine | 1963 |
Urinary amino-acids on phenylalanine-tyrosine-supplemented diets.
Topics: Amino Acids; Diet; Dietary Supplements; Humans; Phenylalanine; Tyrosine | 1963 |
Effects of amino acids, analogs, and certain other agents in relation to tyrosine transport in sarcoma 37 ascites cells.
Topics: Amino Acids; Animals; Ascites; Azides; Cyanides; Iodoacetates; Malonates; Neoplasms; Nitrophenols; Organic Chemicals; Phenylalanine; Sarcoma; Sarcoma 37; Sarcoma, Experimental; Tyrosine | 1962 |
Symposium on metabolic diseases of the eye, Biochemical remarks on amino acid metabolism.
Topics: Alkaptonuria; Amino Acids; Humans; Metabolic Diseases; Phenylalanine; Proteins; Tyrosine | 1963 |
The metabolism of aromatic aminoacids in kwashiorkor.
Topics: Histidine; Humans; Kwashiorkor; Phenylalanine; Proteins; Tryptophan; Tyrosine | 1963 |
The source of oxygen in the phenylalanine hydroxylase and the copamine-beta-hydroxylase catalyzed rections.
Topics: Amino Alcohols; Dopamine; Mixed Function Oxygenases; Oxygen; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1962 |
Fractionation of soluble RNA by chromatography on DEAE ion exchangers.
Topics: Chromatography; Ethanolamines; Leucine; Phenylalanine; RNA; Serine; Tyrosine; Valine | 1963 |
The effect of thyroxine, thyroxine derivatives, thyronine, diiodotyrosine, dioxyphenylalanine and tyrosine on the adrenal ascorbic acid content in the rat.
Topics: Adrenal Glands; Animals; Ascorbic Acid; Diiodotyrosine; Phenylalanine; Rats; Thyronines; Thyroxine; Tyrosine | 1963 |
[Contribution on the metabolism of phenylalanine and tyrosine in barley].
Topics: Edible Grain; Hordeum; Humans; Phenylalanine; Plant Structures; Tyrosine | 1963 |
The activity of phenylalanine hydroxylase of hepatoma and liver of normal and tumorous animals.
Topics: Animals; Biochemical Phenomena; Carcinoma, Hepatocellular; Enzymes; Liver; Liver Neoplasms; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 1961 |
EFFECTS OF CERTAIN AMINO ACIDS ON ANTHRANILATE PRODUCTION IN NEUROSPORA CRASSA.
Topics: Amino Acids; Arginine; Aspartic Acid; Chromatography; Fluorescence; Leucine; Metabolism; Methionine; Neurospora; Neurospora crassa; ortho-Aminobenzoates; Phenylalanine; Proline; Tryptophan; Tyrosine | 1963 |
VARIATION OF FREE AMINO ACIDS IN CORCYRA CEPHALONICA ST. (RICE MOTH LARVAE) DURING SOME B VITAMIN DEFICIENCIES.
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Glutamates; Glycine; Insecta; Larva; Leucine; Moths; Niacin; Phenylalanine; Research; Riboflavin Deficiency; Serine; Thiamine Deficiency; Tyrosine; Valine; Vitamin B 6 Deficiency; Vitamin B Deficiency | 1963 |
[INFLUENCE OF A DEFICIENCY OF PROTEINS AND VARIOUS AMINO ACIDS ON THYROID ACTIVITY STUDIED WITH THE AID OF RADIOACTIVE IODINE].
Topics: Amino Acids; Blood Chemical Analysis; Caseins; Chromatography; Cystine; Iodine; Iodine Isotopes; Lysine; Methionine; Phenylalanine; Propylthiouracil; Protein Deficiency; Proteins; Rats; Research; Thyroid Function Tests; Thyroid Gland; Tryptophan; Tyrosine | 1963 |
EFFECT OF TETRACYCLINES ON THE INTRACELLULAR AMINO ACIDS OF MOLDS.
Topics: Alanine; Amino Acids; Arginine; Fungi; Glutamic Acid; Lysine; Phenylalanine; Proline; Tetracycline; Tetracyclines; Tyrosine | 1963 |
ANTIGENICITY OF POLYPEPTIDES (POLY-ALPHA-AMINO ACIDS). V. STUDIES IN RABBITS.
Topics: Alanine; Animals; Antigens; Freund's Adjuvant; Glutamates; Hemagglutination; Immunodiffusion; Lysine; Peptides; Phenylalanine; Precipitin Tests; Rabbits; Research; Skin Tests; Tyrosine | 1963 |
ANTIGENICITY OF POLYPEPTIDES (POLY-ALPHA-AMINO ACIDS). VI. STUDIES IN RABBITS.
Topics: Alanine; Amino Acids; Animals; Antigens; Aspartic Acid; Glutamates; Hemagglutination; Lysine; Peptides; Phenylalanine; Precipitin Tests; Rabbits; Research; Skin Tests; Tyrosine | 1963 |
ANTIGENICITY OF POLYPEPTIDES (POLY-ALPHA-AMINO ACIDS). VIII. STUDIES IN GUINEA PIGS.
Topics: Alanine; Amino Acids; Animals; Antigens; Glutamates; Guinea Pigs; Lysine; Peptides; Phenylalanine; Research; Skin Tests; Tyrosine | 1963 |
STUDIES ON COLLETOTRICHUM CAPSICI III. THE EFFECT OF INITIAL PH ON THE GROWTH AND AMINO ACID COMPOSITION.
Topics: Alanine; Amino Acids; Aminobutyrates; Arginine; Aspartic Acid; Chromatography; Colletotrichum; Cysteine; Fungi; Glutamates; Glutamine; Glycine; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Phenylalanine; Research; Serine; Tyrosine | 1963 |
STUDIES ON SYNTHETIC POLYPEPTIDE ANTIGENS. X. THE SKIN REACTIVITY OF ACTIVELY IMMUNIZED RABBITS.
Topics: Alanine; Anaphylaxis; Animals; Antigen-Antibody Reactions; Freund's Adjuvant; Glutamine; Lysine; Pathology; Peptides; Phenylalanine; Rabbits; Research; Skin; Skin Tests; Tyrosine | 1963 |
STUDIES ON ACTIVE TRANSPORT OF L-DOPA (DIHYDROXYPHENYLALANINE) INTO BRAIN SLICES.
Topics: Acetates; Alanine; Aniline Compounds; Animals; Biological Transport, Active; Calcium; Calcium, Dietary; Cerebral Cortex; Dihydroxyphenylalanine; Glutamates; Guinea Pigs; Ions; Levodopa; Magnesium; Metabolism; Phenols; Phenylalanine; Research; Sodium; Tyrosine | 1963 |
EXAMINATION OF OPTICALLY EXCITED AMINO-ACIDS BY ELECTRON SPIN RESONANCE AT VERY LOW TEMPERATURE.
Topics: Amino Acids; Chemistry Techniques, Analytical; Cold Temperature; Electron Spin Resonance Spectroscopy; Phenylalanine; Research; Temperature; Tryptophan; Tyrosine | 1963 |
SPECIFICITY OF PEPSIN AND ITS DEPENDENCE ON A POSSIBLE 'HYDROPHOBICBINDING SITE'.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pepsin A; Peptides; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine; Valine | 1963 |
GAS CHROMATOGRAPHY OF AMINO ACIDS. 1. ANALYSIS OF THE MIXTURE OF METHYL-NTRIFLUOROACETYL DERIVATIVES.
Topics: Alanine; Amino Acids; Aspartic Acid; Chromatography; Chromatography, Gas; Fluoroacetates; Glutamates; Glycine; Hydroxyproline; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1963 |
LIGNIFICATION IN EUCALYPTUS. INCORPORATION OF PHENYLALANINE, TYROSINE AND METHIONINE INTO EUCALYPTUS SIDEROXYLON AND EUCALYPTUS CAMALDULENSIS.
Topics: Acetates; Alanine; Carbon Isotopes; Eucalyptus; Methionine; Phenylalanine; Plant Proteins; Proteins; Research; Sapotaceae; Tyrosine | 1963 |
EFFECT OF RESERPINE ON AMINO ACIDS IN BRAIN.
Topics: 5-Hydroxytryptophan; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Glutamates; Histidine; Hydroxyproline; Nitrogen; Pharmacology; Phenylalanine; Proline; Proteins; Rats; Research; Reserpine; Tryptophan; Tyrosine | 1963 |
INDUCED, SOLUBLE PHENYLALANINE HYDROXYLASE FROM PSEUDOMONAS SP. GROWN ON PHENYLALANINE OR TYROSINE.
Topics: Asparagine; Mixed Function Oxygenases; NAD; Phenylalanine; Phenylalanine Hydroxylase; Physiological Phenomena; Proteins; Pseudomonas; Research; Tyrosine | 1963 |
END-PRODUCT REGULATION OF THE GENERAL AROMATIC-PATHWAY IN ESCHERICHIA COLI W.
Topics: 4-Aminobenzoic Acid; Escherichia coli; Ligases; Phenylalanine; Proteins; Research; Shikimic Acid; Tryptophan; Tyrosine | 1963 |
SEMIAUTOMATIC ANALYSIS OF GLUCOSAMINE AND GALACTOSAMINE IN PROTEIN HYDROLYSATES.
Topics: Alanine; Ammonia; Arginine; Chromatography; Galactosamine; Glucosamine; Glycine; Glycoproteins; Hexosamines; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Protein Hydrolysates; Research; Tyrosine; Valine | 1963 |
INSULIN AND INCORPORATION OF AMINO ACIDS INTO PROTEIN OF MUSCLE. 1. ACCUMULATION AND INCORPORATION STUDIES WITH THE PERFUSED RAT HEART.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Azides; Carbon Isotopes; Cyanides; Glutamates; Glycine; Insulin; Lysine; Muscles; Myocardium; Perfusion; Pharmacology; Phenylalanine; Proline; Proteins; Rats; Research; Tyrosine; Valine | 1963 |
TYROSINOSIS.
Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Blood Chemical Analysis; Child; Genetics, Medical; Glycine; Metabolic Diseases; Phenols; Phenylalanine; Phenylpyruvic Acids; Tyrosine; Urine | 1963 |
EFFECT OF CATIONS UPON HYDROPHOBICITY OF YEASTS GROWN IN AMINO ACID MEDIA.
Topics: Amino Acids; Ammonium Compounds; Cations; Chlorides; Culture Media; Glutamic Acid; Histidine; Hydrophobic and Hydrophilic Interactions; Lysine; Nitrogen; Phenylalanine; Proline; Quaternary Ammonium Compounds; Research; Tryptophan; Tyrosine; Valine; Yeasts | 1963 |
THE SOLUBILITY OF AMINO ACIDS AND RELATED COMPOUNDS IN AQUEOUS UREA SOLUTIONS.
Topics: Alanine; Amino Acids; Asparagine; Chemical Phenomena; Chemistry; Glutamine; Glycine; Histidine; Leucine; Methionine; Peptides; Phenylalanine; Research; Solubility; Solvents; Spectrophotometry; Threonine; Tryptophan; Tyrosine; Urea | 1963 |
THE METABOLISM OF PHENYLALANINE AND TYROSINE IN THE PREMATURE INFANT.
Topics: Bilirubin; Blood Chemical Analysis; Folic Acid; Humans; Hydrocortisone; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Metabolic Diseases; Phenylalanine; Proteins; Tyrosine | 1963 |
EVIDENCE FOR DEVIATION IN THE METABOLISM OF TYROSINE IN RHEUMATIC FEVER. PRELIMINARY COMMUNICATION.
Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Blood Chemical Analysis; Child; Chromatography; Colitis; Colitis, Ulcerative; Humans; Phenols; Phenylalanine; Proteins; Psoriasis; Rheumatic Fever; Tyrosine; Urine | 1963 |
[TRIALS OF A NEW ANTIHYPERTENSIVE, ALPHA-METHYL-DOPA (ALDOMET) WITH SPECIAL REFERENCE TO CHANGES IN RETINAL BLOOD FLOW].
Topics: Angiotensins; Antihypertensive Agents; Blood Circulation; Blood Pressure; Blood Pressure Determination; Dopamine; Epinephrine; Hemodynamics; Methyldopa; NAD; Norepinephrine; Phenylalanine; Renin; Retinal Vessels; Serotonin; Tryptophan; Tyrosine | 1963 |
[ON ULTRAVIOLET LUMINESCENCE OF MUSCLES AND MUSCLE PROTEINS].
Topics: Animals; Anura; Fluorescence; Luminescence; Muscle Proteins; Muscles; Phenylalanine; Ranidae; Research; Tryptophan; Tyrosine; Ultraviolet Rays | 1963 |
[CONTRIBUTION TO THE STUDY OF RIBONUCLEOPROTEINS OF NORMAL AND NEOPLASTIC TISSUES].
Topics: Alanine; Arginine; Aspartic Acid; Chemical Phenomena; Chemistry; Glutamates; Glycine; Isoleucine; Leucine; Liver; Lysine; Mice; Neoplasm Proteins; Neoplasms; Nucleoproteins; Phenylalanine; Rats; Research; Ribonucleoproteins; RNA; RNA, Neoplasm; Serine; Threonine; Tyrosine; Valine | 1963 |
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine | 1963 |
EFFECTS OF PHENYLALANINE, PHENYLACETIC ACID, TYROSINE, AND VALINE ON BRAIN AND LIVER SEROTONIN IN RATS.
Topics: Brain; Liver; Metabolism; Pharmacology; Phenylacetates; Phenylalanine; Rats; Research; Serotonin; Tyrosine; Valine | 1963 |
BIOCHEMISTRY OF LUNGS IN RELATION TO SILICOSIS. II. THE EFFECT OF QUARTZ DUST ON THE PROTEIN AMINO ACIDS OF GUINEA PIG LUNG TISSUE.
Topics: Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Collagen; Cystine; Dust; Glutamates; Glycine; Guinea Pigs; Histidine; Hydroxyproline; Isoleucine; Leucine; Lung; Lysine; Methionine; Phenylalanine; Proline; Quartz; Research; Serine; Silicon Dioxide; Silicosis; Threonine; Toxicology; Tyrosine; Valine | 1964 |
UPTAKE OF AMINO ACIDS BY SALMONELLA TYPHIMURIUM.
Topics: Amino Acids; Carbohydrate Metabolism; Carbon Isotopes; Enzymes; Histidine; Phenylalanine; Proteins; Research; Salmonella typhimurium; Tryptophan; Tyrosine | 1964 |
A DETERMINATION OF THE ESSENTIAL AMINO ACID PROPORTIONS NEEDED TO ALLOW RAPID GROWTH IN CHICKS.
Topics: Amino Acids; Amino Acids, Essential; Animals; Animals, Newborn; Arginine; Caseins; Chickens; Cystine; Diet; Dietary Proteins; Glutamates; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Poultry; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
RELATIVE POTENCY OF DIETS CONTAINING AMINO ACIDS AND PROTEINS FOR PROMOTING GROWTH OF RATS.
Topics: Albumins; Amino Acids; Animals, Newborn; Arginine; Cystine; Diet; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nitrogen; Phenylalanine; Proteins; Rats; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
THE AMINO ACIDS COMPOSITION AND NUTRITIVE VALUE OF PROTEINS. V. AMINO ACID REQUIREMENTS AS A PATTERN FOR PROTEIN EVALUATION.
Topics: Albumins; Amino Acids; Caseins; Cystine; Dietary Proteins; Gelatin; Growth; Histidine; Isoleucine; Leucine; Lysine; Methionine; Nutritional Physiological Phenomena; Nutritional Sciences; Nutritive Value; Ovalbumin; Phenylalanine; Proteins; Rats; Research; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
INHIBITION OF THE HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE BY ALPHA-METHYL-DOPA AND SIMILAR COMPOUNDS.
Topics: Antihypertensive Agents; Carboxy-Lyases; Enzyme Inhibitors; Hydroxylation; Liver; Metabolism; Methyldopa; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Rats; Research; Research Design; Tissue Culture Techniques; Tryptophan; Tyrosine | 1964 |
IMPORTANCE OF TRANSPORT IN ALKALOID BIOSYNTHESIS.
Topics: Alkaloids; Biochemical Phenomena; Biological Transport; Carbon Isotopes; Metabolism; Phenylalanine; Plants; Tyrosine | 1964 |
INFLUENCE OF AMINO ACIDS ON RAT LIVER PHENYLALANINE HYDROXYLASE ACTIVITY.
Topics: Alanine; Amides; Amino Acids; Blood Chemical Analysis; Citrates; Glycine; Leucine; Liver; Metabolism; Mixed Function Oxygenases; Phenylalanine; Phenylalanine Hydroxylase; Rats; Research; Tryptophan; Tyrosine | 1964 |
INFLUENCE OF EXCESS DIETARY PHENYLALANINE ON PREGNANT RATS AND THEIR FETUSES.
Topics: Animals; Blood Chemical Analysis; Female; Fetus; Humans; Maternal-Fetal Exchange; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Pregnancy; Pregnancy, Animal; Rats; Research; Tyrosine | 1964 |
TRANSAMINATION OF AROMATIC AMINO ACIDS IN RAT BRAIN.
Topics: 5-Hydroxytryptophan; Amino Acids, Aromatic; Brain; Chromatography; Dihydroxyphenylalanine; Keto Acids; Ketoglutaric Acids; Phenylalanine; Phenylpyruvic Acids; Rats; Research; Tissue Extracts; Transaminases; Tryptophan; Tyrosine | 1964 |
SOME CHARACTERISTICS OF THE SHEEP THYROID GLAND SYSTEM FOR INCORPORATING AMINO ACIDS INTO PROTEIN.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Glucose; Glutamates; Glycine; Ketoglutaric Acids; Leucine; Phenylalanine; Physiology; Proteins; Pyruvates; Research; Serine; Sheep; Succinates; Thyroid Gland; Thyrotropin; Tyrosine; Valine | 1964 |
DETERMINATION OF PHENYLALANINE IN BLOOD AND URINE.
Topics: Blood Chemical Analysis; Body Fluids; Humans; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine; Urine | 1964 |
INCORPORATION OF O18 FROM AIR INTO TYROSINE.
Topics: Animals; Bombyx; Chromatography; Liver; Oxygen; Oxygen Isotopes; Phenylalanine; Proteins; Pseudomonas aeruginosa; Rats; Research; Tyrosine | 1964 |
ACCUMULATION OF RIBONUCLEIC ACID IN BACTERIAL NUCLEAR PREPARATIONS DURING TREATMENT OF WHOLE CELLS WITH 8-AZAGUANINE, TETRACYCLINES, AND OTHER INHIBITORS.
Topics: Anti-Bacterial Agents; Antimetabolites; Azaguanine; Bacillus megaterium; Bacteriological Techniques; Chloramphenicol; Chlortetracycline; Ethionine; Isoleucine; Leucine; Mutation; Nitrogen; Oxytetracycline; Phenylalanine; Proteins; Research; RNA; Sulfur; Tetracyclines; Tryptophan; Tyrosine; Valine | 1964 |
FREE AMINO ACIDS OF HUMAN BREAST CANCER.
Topics: Amino Acids; Asparagine; Aspartic Acid; Breast Neoplasms; Chromatography; Citrulline; Glutamates; Glutamine; Glycine; Humans; Isoleucine; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
THE BINDING OF IODOTYROSINES WITH SERUM PROTEINS.
Topics: Animals; Anura; Blood Protein Electrophoresis; Blood Proteins; Cattle; Dialysis; Iodine Isotopes; Monoiodotyrosine; Phenylalanine; Precipitin Tests; Rats; Renal Dialysis; Research; Thyroid Function Tests; Tyrosine | 1964 |
SEROTONIN DEFICIENCY IN INFANCY AS ONE CAUSE OF A MENTAL DEFECT IN PHENYLKETONURIA.
Topics: Animals; Animals, Newborn; Behavior; Catecholamines; Chlorpromazine; Genetics; Learning; Metabolic Diseases; Metabolism; Mice; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Research; Reserpine; Serotonin; Toxicology; Tyrosine | 1964 |
THE ROLE OF DISPENSABLE AMINO ACIDS IN THE NUTRITION OF THE RAT.
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Bicarbonates; Caseins; Cystine; Dietary Proteins; Glutamates; Glycine; Growth; Histidine; Isoleucine; Lysine; Methionine; Phenylalanine; Proline; Proteins; Rats; Research; Serine; Tyrosine | 1964 |
THE EFFECT OF URAEMIC BLOOD CONSTITUENTS ON CERTAIN CEREBRAL ENZYMES.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Benzoates; Brain; Carbohydrate Metabolism; Carboxy-Lyases; Cinnamates; Enzyme Inhibitors; Guinea Pigs; Hippurates; L-Lactate Dehydrogenase; Lactates; Mandelic Acids; Manometry; Metabolism; Monoamine Oxidase; Nucleotidases; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Spectrophotometry; Tryptophan; Tyrosine; Uremia | 1964 |
THE CONTENT OF AMINO ACIDS IN THE PROTEINS OF THE DEVELOPING NERVOUS SYSTEM OF THE GUINEA PIG. III. SPINAL CORD.
Topics: Aging; Amino Acids; Animals; Animals, Newborn; Arginine; Aspartic Acid; Cystine; Fetus; Glutamates; Glycine; Guinea Pigs; Histidine; Leucine; Lysine; Nerve Tissue Proteins; Nervous System; Phenylalanine; Research; Serine; Spinal Cord; Threonine; Tyrosine; Valine | 1964 |
POLYNUCLEOTIDE ANALOGUES. II. STIMULATION OF AMINO ACID INCORPORATION BY POLYNUCLEOTIDE ANALOGUES.
Topics: Amino Acids; Carbon Isotopes; Chromatography; Cysteine; Escherichia coli; Glycine; Isoleucine; Leucine; Lysine; Pharmacology; Phenylalanine; Polynucleotides; Proline; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Uracil Nucleotides; Valine | 1964 |
MIGRATION OF AMINO ACIDS ACROSS THE MEMBRANE OF THE HUMAN ERYTHROCYTE.
Topics: Alanine; Amino Acids; Aminoisobutyric Acids; Biological Transport; Carbon Isotopes; Erythrocytes; Glycine; Histidine; Leucine; Methionine; Permeability; Phenylalanine; Proteins; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
ANTIGENICITY OF POLYPEPTIDES (POLY-ALPHA-AMINO ACIDS). XI. QUANTITATIVE RELATIONSHIPS AMONG POLYMERS AND RABBIT ANTISERA.
Topics: Alanine; Amino Acids; Anaphylaxis; Animals; Antigen-Antibody Reactions; Antigens; Complement Fixation Tests; Glutamates; Guinea Pigs; Immune Sera; Lysine; Peptides; Phenylalanine; Polymers; Precipitin Tests; Rabbits; Research; Tyrosine | 1964 |
HYDROLYTIC ENZYMES OF RABBIT MONONUCLEAR EXUDATE CELLS. I. QUANTITATIVE ASSAY AND PROPERTIES OF CERTAIN PROTEASES, NON-SPECIFIC ESTERASES, AND LIPASES OF MONONUCLEAR AND POLYMORPHONUCLEAR CELLS AND ERYTHROCYTES.
Topics: Animals; Azoles; Benzoates; Calcium; Carboxylesterase; Dipeptides; Edetic Acid; Endopeptidases; Enzyme Inhibitors; Erythrocytes; Esterases; Exudates and Transudates; Hemoglobins; Hydrogen-Ion Concentration; Hydrolysis; Leukocytes; Lipase; Lymphocytes; Macrophages; Naphthalenes; Naphthols; Peptide Hydrolases; Phenylalanine; Protamines; Rabbits; Research; Sodium Chloride; Taurine; Tyrosine | 1964 |
DYNAMIC PHENOMENA IN MICROSPHERES FROM THERMAL PROTEINOID.
Topics: Alanine; Arginine; Aspartic Acid; Colloids; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Microspheres; Peptides; Phenylalanine; Photomicrography; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[SEPARATION OF AMINO ACIDS BY CHROMATOGRAPHY ON THIN LAYERS OF DIETHYLAMINOETHYL CELLULOSE].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Aspartic Acid; Cellulose; Chromatography; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Research; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
EFFECTS OF GAMMA RADIATION ON RIBONUCLEASE.
Topics: Cobalt Isotopes; Gamma Rays; Methionine; Pancreas; Phenylalanine; Radiation Effects; Research; Ribonucleases; Spectrum Analysis; Tyrosine | 1964 |
INTESTINAL TRANSPORT OF TRYPTOPHAN AND ITS DERIVATIVES.
Topics: Absorption; Animals; Biological Transport; Choline; Cricetinae; Intestines; Ion Exchange; Lithium; Phenylalanine; Physiology; Potassium; Proteins; Research; Sodium; Sodium, Dietary; Tryptophan; Tyrosine | 1964 |
AMINO ACID METABOLISM IN KWASHIORKOR. II. METABOLISM OF PHENYLALANINE AND TYROSINE.
Topics: Blood Chemical Analysis; Child; Chromatography; Dietary Proteins; Humans; Infant; Kwashiorkor; Milk; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Proteins; Tyrosine; Urine | 1964 |
THE ABNORMAL LIGNINS PRODUCED BY THE BROWN-MIDRIB MUTANTS OF MAIZE. I. THE BROWN-MIDRIB-1 MUTANT.
Topics: Carbon Isotopes; Chromatography; Cinnamates; Dioxins; Edible Grain; Lignin; Mutation; Nitrobenzenes; Phenylalanine; Proteins; Research; Tyrosine; Zea mays | 1964 |
CHROMATOGRAPHIC SEPARATION OF PYRIDOXYL DERIVATIVES OF AMINO ACIDS.
Topics: Alanine; Amines; Amino Acids; Arginine; Aspartic Acid; Chromatography; Glutamates; Glycine; Histidine; Leucine; Lysine; Methionine; Phenylalanine; Pyridines; Pyridoxine; Research; Serine; Threonine; Tyrosine; Valine | 1964 |
A MODIFIED METHOD FOR THE SEPARATION OF BASIC AMINO ACIDS ON THE AUTOMATIC AMINO ACID ANALYZER.
Topics: Amino Acids; Amino Acids, Basic; Aminobutyrates; Ammonia; Arginine; Autoanalysis; Chromatography; Creatine; Creatinine; Hexosamines; Histidine; Lysine; Muscles; Ornithine; Peptides; Phenylalanine; Rabbits; Research; Tryptophan; Tyrosine | 1964 |
PUROMYCIN INHIBITION OF PROTEIN SYNTHESIS: INCORPORATION OF PUROMYCIN INTO PEPTIDE CHAINS.
Topics: Amino Acids; Anti-Bacterial Agents; Biochemical Phenomena; Biochemistry; Chloramphenicol; Chromatography; Chymotrypsin; Electrophoresis; Enzyme Inhibitors; Escherichia coli; Peptides; Phenylalanine; Protein Biosynthesis; Proteins; Puromycin; Research; Ribosomes; RNA; RNA, Bacterial; Tritium; Trypsin; Tyrosine | 1964 |
EVIDENCE FOR DEGENERACY AND AMBIGUITY IN INTERSPECIES AMINOACYL-SRNA FORMATION.
Topics: Alanine; Bacterial Proteins; Carbon Isotopes; Chromatography; Enzymes; Escherichia coli; Neurospora; Phenylalanine; Proteins; Research; RNA; RNA, Bacterial; Species Specificity; Tritium; Tyrosine | 1964 |
BRAIN SEROTONIN IN EXPERIMENTAL TYROSINOSIS.
Topics: Amino Acid Metabolism, Inborn Errors; Ascorbic Acid; Blood; Brain; Carboxy-Lyases; Guinea Pigs; Metabolic Diseases; Monoamine Oxidase; Pharmacology; Phenylalanine; Phenylketonurias; Research; Serotonin; Toxicology; Tyrosine | 1964 |
SERUM AMINO ACIDS IN KWASHIORKOR. I. RELATIONSHIP TO CLINICAL CONDITION.
Topics: Alanine; Amino Acids; Biomedical Research; Black People; Blood; Glutamates; Glutamine; Glycine; Infant; Isoleucine; Kwashiorkor; Leucine; Methionine; Phenylalanine; Serine; Threonine; Tyrosine; Uganda; Valine | 1964 |
DIFFERENCES IN CHLORAMPHENICOL SENSITIVITY OF CELL-FREE AMINO ACID POLYMERIZATION SYSTEMS.
Topics: Adenine Nucleotides; Amino Acids; Antimetabolites; Carbon Isotopes; Cell-Free System; Chloramphenicol; Escherichia coli; Isoleucine; Leucine; Micrococcus; Nucleoproteins; Nucleotidases; Pharmacology; Phenylalanine; Plant Viruses; Polymerization; Polynucleotides; Proteins; Research; RNA; RNA, Bacterial; RNA, Messenger; RNA, Viral; Serine; Tyrosine; Uracil Nucleotides | 1964 |
PREVENTION OF A MENTAL DEFECT OF PHENYLKETONURIA WITH SEROTONIN CONGENERS SUCH AS MELATONIN OR HYDROXYTRYPTOPHAN.
Topics: 5-Hydroxytryptophan; Animals; Biomedical Research; Indoles; Learning; Melatonin; Mice; Pharmacology; Phenylalanine; Phenylketonurias; Research; Serotonin; Tyrosine | 1964 |
INCORPORATION OF LABELLED COMPOUNDS INTO AFLATOXINS.
Topics: Acetates; Aflatoxins; Antitoxins; Aspergillus; Carbon Isotopes; Cinnamates; Lactones; Metabolism; Methionine; Mevalonic Acid; Pharmacology; Phenylalanine; Proteins; Research; Shikimic Acid; Toxins, Biological; Tryptophan; Tyrosine; Ultraviolet Rays | 1964 |
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase | 1964 |
THE ROLE OF PTERIDINES IN THE ENZYMATIC CONVERSION OF PHENYLALANINE TO TYROSINE.
Topics: Coenzymes; Dihydroxyphenylalanine; Humans; Liver; Metabolism; Nucleotides; Phenylalanine; Pteridines; Pterins; Tyrosine | 1964 |
SOME OBSERVATIONS ON PIGMENTS INDUCED BY P-AMINOBENZOIC ACID IN NEUROSPORA CRASSA CULTURES.
Topics: 4-Aminobenzoic Acid; Benzoates; Folic Acid; Hydrogen-Ion Concentration; Neurospora; Neurospora crassa; Niacin; Nicotinic Acids; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Pigments, Biological; Procaine; Research; Tyrosine | 1964 |
SOME BIOCHEMICAL LESSONS TO BE LEARNED FROM PHENYLKETONURIA.
Topics: Glutamates; Humans; Indican; Indoleacetic Acids; Indoles; Learning; Metabolism; Phenylacetates; Phenylalanine; Phenylketonurias; Pterins; Serotonin; Tryptophan; Tyrosine | 1964 |
[ATTEMPTS AT PHOTOCHEMICAL AMINE FORMATION].
Topics: Dopamine; Phenethylamines; Phenylalanine; Tryptamines; Tryptophan; Tyramine; Tyrosine; Ultraviolet Rays | 1964 |
ENDOGENOUS RENAL CLEARANCES OF 12 INDIVIDUAL AMINO ACIDS IN FOUR APPARENTLY HEALTHY SUBJECTS AND IN FOUR AMINOACIDURIC PERSONS OF A KINDRED WITH HEREDITARY PANCREATITIS.
Topics: Amino Acids; Arginine; Biomedical Research; Cystine; Genetics, Medical; Glutamates; Healthy Volunteers; Histidine; Isoleucine; Kidney; Leucine; Lysine; Methionine; Pancreatitis; Pancreatitis, Chronic; Phenylalanine; Physiology; Renal Aminoacidurias; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
[ON THE HORMONAL REGULATION OF PROTEIN METABOLISM. THE EFFECT ON INSULIN AND GLUCAGON].
Topics: Alanine; Arginine; Aspartic Acid; Blood Glucose; Carbohydrate Metabolism; Glucagon; Glutamates; Glycine; Histidine; Insulin; Leucine; Lysine; Pharmacology; Phenylalanine; Proteins; Threonine; Tyrosine; Valine | 1964 |
PREPARATION OF PREPHENIC ACID AND ITS CONVERSION TO PHENYLALANINE AND TYROSINE BY PLANT ENZYMES.
Topics: Autoanalysis; Barium; Cyclohexanecarboxylic Acids; Cyclohexenes; Escherichia coli; Fermentation; Glutamates; Infrared Rays; Ion Exchange Resins; NADP; Peptones; Phenylalanine; Phenylpyruvic Acids; Plants, Edible; Proteins; Research; Transaminases; Tyrosine; Yeasts | 1964 |
THE EFFECTS OF PHENYLALANINE AND TYROSINE ANALOGS ON THE SYNTHESIS AND ACTIVITY OF 3-DEOXY-D-ARABINO-HEPTULOSONIC ACID 7-PHOSPHATE SYNTHETASES.
Topics: Carbohydrate Metabolism; Enzyme Inhibitors; Escherichia coli; Ligases; Mutation; Naphthalenes; Pharmacology; Phenylalanine; Phosphates; Pyridines; Research; Thiazoles; Thiophenes; Tyrosine | 1964 |
MECHANISM OF HORMONAL CONTROL OF RAT LIVER TYROSINE TRANSAMINASE.
Topics: Adrenalectomy; Antigen-Antibody Reactions; Ethionine; Hydrocortisone; Leucine; Liver; Methionine; Phenylalanine; Rats; Research; Transaminases; Tyrosine; Tyrosine Transaminase | 1963 |
STUDIES ON TYROSINOSIS: 1, EFFECT OF LOW-TYROSINE AND LOW-PHENYLALANINE DIET.
Topics: Acetates; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Diet; Diet Therapy; Hepatomegaly; Humans; Kidney; Kidney Function Tests; Lactates; Liver Diseases; Liver Function Tests; Phenylalanine; Phenylpyruvic Acids; Phosphates; Renal Aminoacidurias; Rickets; Tyrosine; Urine | 1964 |
PHENYLALANINE REQUIREMENTS WITH DIFFERENT LEVELS OF TYROSINE.
Topics: Amino Acids; Metabolism; Nitrogen; Phenylalanine; Tyrosine | 1964 |
SLOW EXPONENTIAL GROWTH OF ESCHERICHIA COLI IN PRESENCE OF RHO-FLUOROPHENYLALANINE. EFFECT OF THE ANALOG ON AROMATIC BIOSYNTHESIS.
Topics: Amino Acids; Carbon Isotopes; Cell Division; Drug Resistance; Drug Resistance, Microbial; Escherichia coli; Fluorocarbon Polymers; Mutation; Phenylalanine; Phenylpyruvic Acids; Research; Shikimic Acid; Tyrosine | 1964 |
VALINE OLIGONUCLEOTIDE COMPLEXES PRODUCED BY T1-RIBONUCLEASE FROM VALINE-ACCEPTOR RIBONUCLEIC ACID.
Topics: Biochemical Phenomena; Biochemistry; Leucine; Oligonucleotides; Phenylalanine; Polynucleotides; Research; Ribonuclease T1; Ribonucleases; RNA; Tritium; Tyrosine; Valine | 1964 |
INTERACTIONS OF PURINE WITH PROTEINS AND AMINO ACIDS.
Topics: Alanine; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Glycine; Histidine; Hot Temperature; Muramidase; Phenylalanine; Proteins; Purines; Research; Ribonucleases; Serum Albumin; Serum Albumin, Bovine; Tryptophan; Tyrosine | 1964 |
INHIBITION OF TRYPSIN BY COPOLYMERS OF GLUTAMIC ACID AND OTHER AMINO ACIDS.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Chymotrypsin; Colorimetry; Glutamates; Glutamic Acid; Leucine; Peptides; Phenylalanine; Research; Trypsin; Trypsin Inhibitors; Tyrosine; Urea | 1964 |
UROLITHIASIS IN THE RAT. IV. INFLUENCE OF AMINO ACID SUPPLEMENTS ON THE OCCURRENCE OF CITRATE CALCULI.
Topics: Amino Acids; Calcium; Caseins; Citrates; Citric Acid; Cystine; Dietary Proteins; Glutamates; Isoleucine; Kidney Calculi; Leucine; Lysine; Methionine; Phenylalanine; Proteins; Rats; Research; Threonine; Tryptophan; Tyrosine; Valine | 1964 |
STUDIES ON THE HYDROLYTIC ACTION OF PRONASE ON DERIVATIZED AND NON-DERIVATIZED PROTEINS.
Topics: Alanine; Arginine; Asparagine; Cystine; Dinitrophenols; Glutamates; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptide Hydrolases; Phenylalanine; Proline; Pronase; Proteins; Research; Ribonucleases; Streptomyces; Threonine; Tyrosine; Valine | 1964 |
CHEMICAL DIAGNOSIS OF PHENYLKETONURIA. REPORT OF 8 CASES.
Topics: Adolescent; Blood Chemical Analysis; Body Fluids; Child; China; Chromatography; Clinical Laboratory Techniques; Genes; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine; Urine | 1964 |
[FREE PLASMA AMINO ACIDS IN LIVER CIRRHOSIS AND HEPATITIS].
Topics: Alanine; Amino Acids; Blood; Chromatography; Glutamine; Glycine; Hepatitis; Humans; Ion Exchange Resins; Liver Cirrhosis; Methionine; Phenylalanine; Proline; Serine; Taurine; Threonine; Tyrosine | 1964 |
DETERMINATION OF NUCLEOTIDE SEQUENCES IN S-RNA. 3. ISOLATION OF OLIGONUCLEOTIDES FROM THE ACCEPTOR END OF AMINO ACID-SPECIFIC ACCEPTOR CHAINS OF SOLUBLE RIBONUCLEIC ACID.
Topics: Amino Acids; Ammonium Compounds; Base Sequence; Carbon Isotopes; Chromatography; Dialysis; Electrophoresis; Leucine; Metabolism; Nucleosides; Nucleotides; Oligonucleotides; Phenylalanine; Quaternary Ammonium Compounds; Renal Dialysis; Research; Ribonucleases; RNA; Tritium; Tyrosine; Valine; Yeasts | 1964 |
FURTHER STUDIES OF PLASMA TYROSINE IN PATIENTS WITH ALTERED THYROID FUNCTION.
Topics: Amino Acids; Blood Chemical Analysis; Fasting; Geriatrics; Glutamates; Humans; Hyperthyroidism; Myxedema; Pharmacology; Phenylalanine; Triiodothyronine; Tryptophan; Tyrosine | 1964 |
MYOGLOBIN FREE-RADICALS.
Topics: Alanine; Chemical Phenomena; Chemistry; Dihydroxyphenylalanine; Glycine; Histidine; Hydrogen Peroxide; Leucine; Myoglobin; Phenylalanine; Proline; Research; Serine; Threonine; Tyrosine | 1964 |
ELECTRONIC EFFECTS AND L-AMINO-ACID OXIDASE SPECIFICITY.
Topics: Alanine; Amino Acid Oxidoreductases; Amino Acids; L-Amino Acid Oxidase; Leucine; Phenylacetates; Phenylalanine; Research; Snakes; Tryptophan; Tyrosine; Venoms | 1964 |
[BIOCHEMICAL STUDIES ON EXPERIMENTAL PHENYLKETONURIA].
Topics: Amino Acids; Animals; Aspartic Acid; Diet; Discrimination Learning; Glutamine; Haplorhini; Phenylalanine; Phenylketonurias; Pyruvates; Rabbits; Rats; Research; Tyrosine | 1964 |
SUBSTRATE SPECIFICITY OF DOPA DECARBOXYLASE.
Topics: Animals; Carbon Dioxide; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Guinea Pigs; Kidney; Phenylalanine; Radiometry; Research; Substrate Specificity; Tyrosine | 1964 |
THE RESPONSE OF THREE CATALYTICALLY FUNCTIONAL GROUPS IN CHYMOTRYPSIN TO CHANGES IN ACIDITY.
Topics: Acids; Anilides; Catalysis; Chymotrypsin; Hydrogen-Ion Concentration; Imidazoles; Phenols; Phenylalanine; Research; Tyrosine | 1964 |
AMINO ACID CODING IN A SUBCELLULAR SYSTEM DERIVED FROM THE L1210 MOUSE ASCITES LEUKEMIA.
Topics: Adenine Nucleotides; Amino Acids; Animals; Ascites; Genetic Code; Isoleucine; Leucine; Leukemia L1210; Lysine; Neoplasm Proteins; Phenylalanine; Proteins; Research; Serine; Tyrosine; Valine | 1964 |
EFFECT OF THE PHYSICAL ENVIRONMENT ON EXCITED STATES OF AMINO ACIDS AND PROTEINS.
Topics: Amino Acids; Chemical Phenomena; Chemistry, Physical; Fluorescence; Luminescence; Phenylalanine; Proteins; Ribonucleases; Tryptophan; Tyrosine | 1964 |
NONCOVALENT INTERACTIONS BETWEEN AMINO ACID SIDE CHAINS AND A COENZYME MODEL.
Topics: Amino Acids; Coenzymes; Fluorescence; Fluorometry; Histidine; Imidazoles; Indoles; Lysine; Methionine; NAD; Phenols; Phenylalanine; Pyridines; Research; Spectrum Analysis; Tyramine; Tyrosine | 1964 |
STUDIES OF THE BIOSYNTHESIS OF THYROXINE. I. PURIFICATION AND PROPERTIES OF A PARTICULATE IODIDE PEROXIDASE FROM THYROID TISSUE.
Topics: Albumins; Animals; Caseins; Cattle; Chromatography; Cobalt; Copper; Cyanides; Diiodotyrosine; Enzyme Inhibitors; Histidine; Hydrogen Peroxide; Iodide Peroxidase; Iodides; Iodine; Metabolism; Peroxidases; Pharmacology; Phenylalanine; Propylthiouracil; Research; Thyroglobulin; Thyroid Gland; Thyroxine; Trypsin; Tyrosine | 1964 |
BIOCHEMICAL CORRELATES IN RATS WITH PHENYLKETONURIA.
Topics: Blood; Brain Chemistry; Liver; Mixed Function Oxygenases; Phenylalanine; Phenylketonurias; Rats; Research; Serotonin; Transaminases; Tyrosine | 1964 |
STUDIES ON THE ROLE OF METHYLATED BASES IN THE BIOLOGICAL ACTIVITY OF SOLUBLE RIBONUCLEIC ACID.
Topics: Alkylation; Amino Acids; Arginine; Carbon Isotopes; Histidine; Isoleucine; Kinetics; Leucine; Metabolism; Methionine; Phenylalanine; Purines; Pyrimidines; Research; RNA; Tyrosine; Valine | 1964 |
AMINO ACIDS AS PROTECTIVE COMPOUNDS IN ULTRAVIOLET-IRRADIATED HANSENULA WINGEI.
Topics: Alanine; Amino Acids; Arginine; Cysteine; Cystine; Ethionine; Glutamates; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Pichia; Proline; Radiation-Protective Agents; Research; Serine; Threonine; Tryptophan; Tyrosine; Ultraviolet Rays; Valine; Yeasts | 1964 |
EFFECT OF GLUCOSE INFUSION ON THE INDIVIDUAL PLASMA FREE AMINO ACIDS IN MAN.
Topics: Amino Acids; Blood; Glucose; Humans; Insulin; Isoleucine; Leucine; Male; Pharmacology; Phenylalanine; Threonine; Tyrosine; Valine | 1964 |
ON THE INFLUENCE OF THE ADMINISTRATION OF AMINO ACIDS UPON THE DISTRIBUTION OF PORPHYRIN BODIES IN TISSUES. X. THE INFLUENCE OF THE ADMINISTRATION OF AROMATIC AMINO ACIDS.
Topics: Amino Acids; Amino Acids, Aromatic; Animals; Dihydroxyphenylalanine; Guinea Pigs; Histocytochemistry; Pharmacology; Phenylalanine; Porphyrins; Research; Tryptophan; Tyrosine | 1964 |
HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE IN NEOPLASTIC MAST CELLS OF THE MOUSE.
Topics: Animals; Hydroxylation; Indoles; Mast Cells; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Phenylalanine; Research; Tryptophan; Tyrosine | 1964 |
LACK OF FIDELITY IN THE TRANSLATION OF SYNTHETIC POLYRIBONUCLEOTIDES.
Topics: Bacillus; Dihydrostreptomycin Sulfate; Isoleucine; Leucine; Magnesium; Metabolism; Nucleotides; Phenylalanine; Polyribonucleotides; Proteins; Research; RNA; RNA, Messenger; Serine; Spermine; Temperature; Tyrosine; Valine | 1964 |
POLYMERIZATION REACTIONS CATALYZED BY INTRACELLULAR PROTEINASES. IV. FACTORS INFLUENCING THE POLYMERIZATION OF DIPEPTIDE AMIDES BY CATHEPSIN C.
Topics: Amides; Cathepsin C; Cathepsins; Chemical Phenomena; Chemistry; Dipeptides; Endopeptidases; Glycine; Hydrogen-Ion Concentration; Peptide Hydrolases; Phenylalanine; Polymerization; Research; Tryptophan; Tyrosine | 1964 |
SEPARATION OF TRYPTIC PEPTIDES OF TOBACCO MOSAIC VIRUS AND STRAIN PROTEINS BY AN IMPROVED METHOD OF COLUMN CHROMATOGRAPHY.
Topics: Amino Acids; Chromatography; Peptides; Phenylalanine; Research; Tobacco Mosaic Virus; Trypsin; Tyrosine; Viral Proteins | 1964 |
THE INCORPORATION OF LABELED AMINO ACIDS INTO LENS PROTEIN.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Carbon Isotopes; Cattle; Chromatography; Crystallins; Eye Proteins; Histidine; Lens, Crystalline; Phenylalanine; Proteins; Rabbits; Research; Tyrosine | 1964 |
THE UNFOLDING AND REFOLDING OF RIBONUCLEASE IN UREA SOLUTIONS. I. RATES AND EXTENTS OF PHYSICAL CHANGES.
Topics: Adenine Nucleotides; Chemical Phenomena; Chemistry, Physical; Cytosine Nucleotides; Indicators and Reagents; Kinetics; Phenylalanine; Phosphates; Research; Ribonucleases; Solubility; Solutions; Spectrophotometry; Tyrosine; Urea | 1964 |
INHIBITION OF ADP-INDUCED PLATELET AGGREGATION BY SUBSTITUTED AMINO-ACIDS.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Alanine; Alkylation; Amino Acids; Aminocaproates; Aminocaproic Acid; Arginine; Blood Platelets; Butyrates; Glutamine; Glycine; Guanidines; Leucine; Pharmacology; Phenylalanine; Platelet Aggregation; Proline; Research; Thrombosis; Tyrosine | 1964 |
ESTERASE ACTIVITY OF PEPSIN.
Topics: Amino Acids; Biochemical Phenomena; Biochemistry; Chromatography; Enzyme Precursors; Esterases; Lactates; Pepsin A; Phenylacetates; Phenylalanine; Research; Spectrophotometry; Tyrosine | 1964 |
MUTATIONAL ALTERATION OF PERMEABILITY IN NEUROSPORA: EFFECTS ON GROWTH AND THE UPTAKE OF CERTAIN AMINO ACIDS AND RELATED COMPOUNDS.
Topics: Amino Acids; Culture Media; Genetics; Leucine; Mutation; Neurospora; Permeability; Phenylalanine; Research; Tryptophan; Tyrosine | 1964 |
MICROMETHODS FOR MEASURING PHENYLALANINE AND TYROSINE IN SERUM.
Topics: Blood; Hematologic Tests; Humans; Microchemistry; Phenylalanine; Research; Spectrophotometry; Tyrosine | 1964 |
UTILIZATION OF AROMATIC AMINO ACIDS BY HYDROGENOMONAS FACILIS.
Topics: 4-Aminobenzoic Acid; Amino Acids; Amino Acids, Aromatic; Benzoates; Carbon Isotopes; Comamonadaceae; Glucose; Hydroxybenzoates; Metabolism; Oxidation-Reduction; Phenylalanine; Quinic Acid; Research; Tryptophan; Tyrosine | 1964 |
AUTORADIOGRAPHIC EVIDENCE OF A NUCLEAR HISTONE SYNTHESIS DURING MOUSE SPERMIOGENESIS IN THE ABSENCE OF DETECTABLE QUANTITIES OF NUCLEAR RIBONUCLEIC ACID.
Topics: Amino Acids; Animals; Arginine; Autoradiography; Cell Nucleus; Histidine; Histones; Leucine; Lysine; Male; Mice; Phenylalanine; Proteins; Research; RNA; Spermatogenesis; Spermatozoa; Tritium; Tryptophan; Tyrosine | 1964 |
SPECIFIC BINDING OF SRNA WITH THE TEMPLATE-RIBOSOME COMPLEX.
Topics: Carbon Isotopes; Chromatography; Leucine; Lysine; Phenylalanine; Polynucleotides; Proteins; Radiometry; Research; Ribonucleases; Ribosomes; RNA; RNA, Bacterial; RNA, Messenger; Tritium; Tyrosine; Uracil Nucleotides | 1964 |
ANOMALOUS BEHAVIOR OF PLASMA ALBUMIN TYROSINE DERIVED FROM ADMINISTERED PHENYLALANINE.
Topics: Amino Acids; Blood Proteins; Carbon Isotopes; Dogs; Phenylalanine; Research; Serum Albumin; Tyrosine | 1964 |
TREATMENT OF LEUKAEMIA BY AMINOACID IMBALANCE.
Topics: Amino Acids; Child; Diet; Diet Therapy; Dietary Proteins; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Lymphocytes; Neoplasms; Phenylalanine; Tyrosine | 1965 |
[CHANGES IN THE TRYPTOPHAN METABOLISM IN PHENYLKETONURIA].
Topics: Amino Acids; Blood; Body Fluids; Child; Humans; Phenylalanine; Phenylketonurias; Tryptophan; Tyrosine; Urine | 1964 |
STUDIES ON COENZYME Q. PATTERN OF LABELING IN COENZYME Q9 AFTER ADMINISTRATION OF ISOTOPIC ACETATE AND AROMATIC AMINO ACIDS TO RATS.
Topics: Acetates; Amino Acids; Amino Acids, Aromatic; Carbon Isotopes; Chromatography; Liver; Metabolism; Pharmacology; Phenylalanine; Rats; Research; Tyrosine; Ubiquinone | 1965 |
ON THE STABILITY OF AMINOACYL-S-RNA TO NUCLEOPHILIC CATALYSIS.
Topics: Amino Alcohols; Buffers; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Ethylenediamines; Imidazoles; Lysine; Morpholines; Phenylalanine; Research; RNA; Tromethamine; Tyrosine; Valine | 1964 |
THE BIOCHEMICAL MECHANISM OF ACTION OF L-PHENYLALANINE MUSTARD. I. DISTRIBUTION OF L-PHENYLALANINE MUSTARD-H3 IN TUMOR-BEARING RATS.
Topics: Animals; Bone Marrow; Carcinoma 256, Walker; Chromatography; DNA; Intestines; Kidney; Liver; Melphalan; Metabolism; Muscles; Mustard Plant; Neoplasms; Pharmacology; Phenylalanine; Plasma; Rats; Research; Spleen; Thymus Gland; Tritium; Tyrosine | 1965 |
[SEX-SPECIFIC DIFFERENCES OF SERUM AMINO ACID CONCENTRATIONS].
Topics: Amino Acids; Biomedical Research; Blood; Chromatography; Cystine; Isoleucine; Leucine; Phenylalanine; Pregnancy; Sex; Tyrosine; Valine | 1965 |
DISSOCIATION OF AMINO ACID ACCEPTOR FUNCTION OF SRNA FROM ITS TRANSFER FUNCTION.
Topics: Alanine; Amino Acids; Bacillus subtilis; Carbon Isotopes; Chemical Phenomena; Chemistry; Escherichia coli; Leucine; Ligases; Lysine; Magnesium; Phenylalanine; Radiometry; Research; Ribonucleases; RNA; RNA, Bacterial; Tyrosine; Valine | 1965 |
ON THE MECHANISM OF THE BRAIN SEROTONIN DEPLETION IN EXPERIMENTAL PHENYLKETONURIA.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Ascorbic Acid; Blood; Brain; Brain Chemistry; Carboxy-Lyases; Cholinesterases; Corticosterone; Dopamine; Glutamates; Liver; Metabolism; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Phenylketonurias; Rats; Research; Serotonin; Transaminases; Tryptophan; Tyrosine | 1965 |
PHENYLALANINE HYDROXYLATION BY PSEUDOMONAS SPECIES (ATCC 11299A).
Topics: Asparagine; Carbon Isotopes; Culture Media; Hydroxylation; Iron; Keto Acids; Metabolism; Mixed Function Oxygenases; NAD; Phenylalanine; Pseudomonas; Pterins; Radiometry; Research; Tyrosine | 1965 |
SEPARATION AND PURIFICATION OF AROMATIC AMINO ACID TRANSAMINASES FROM RAT BRAIN.
Topics: Amino Acids; Brain; Chemical Phenomena; Chemical Precipitation; Chemistry; Chromatography; Chromatography, Gel; Phenylalanine; Rats; Research; Spectrophotometry; Transaminases; Tryptophan; Tyrosine | 1965 |
THE FATE OF SEROTONIN IN THE CELL OF THE MUSSEL MYTILUS EDULIS.
Topics: Animals; Chromatography; Cyanides; Cytochromes; Enzyme Inhibitors; Enzymes; Epinephrine; Fluorescence; Fluorometry; Metabolism; Mollusca; Mytilus edulis; Oxidoreductases; Pharmacology; Phenylalanine; Physiology, Comparative; Pigments, Biological; Research; Serotonin; Spectrum Analysis; Tryptophan; Tyrosine | 1965 |
REQUIREMENT FOR P-FLUOROPHENYLALANINE ACTIVATION IN CONTROL OF RIBONUCLEIC ACID SYNTHESIS.
Topics: Carbon Isotopes; Escherichia coli; Feedback; Fluorides; Fluorine; Ligases; Metabolism; Mutation; p-Fluorophenylalanine; Pharmacology; Phenylalanine; Radiometry; Research; RNA; RNA, Bacterial; Shikimic Acid; Tryptophan; Tyrosine | 1965 |
FALSE FEEDBACK INHIBITION OF AROMATIC AMINO ACID BIOSYNTHESIS BY BETA-2-THIENYLALANINE.
Topics: Alanine; Amino Acids; Amino Acids, Aromatic; Escherichia coli; Feedback; Ligases; Metabolism; Mutation; Pharmacology; Phenylalanine; Proteins; Research; RNA; Shikimic Acid; Thiophenes; Tryptophan; Tyrosine | 1965 |
[FREE PLASMA AMINO ACIDS AND BLOOD AMMONIA FOLLOWING ORAL PROTEIN LOAD. STUDIES IN NORMAL PERSONS AND PATIENTS WITH LIVER CIRRHOSIS].
Topics: Amino Acids; Ammonia; Arginine; Aspartic Acid; Blood; Dietary Proteins; Glutamates; Humans; Liver Cirrhosis; Lysine; Methionine; Ornithine; Phenylalanine; Proteins; Tyrosine | 1965 |
STUDIES ON POLYNUCLEOTIDES. XLI. PURIFICATION OF PHENYLALANINE-SPECIFIC TRANSFER RIBONUCLEIC ACID FROM YEAST BY COUNTERCURRENT DISTRIBUTION.
Topics: Amino Acids; Biochemical Phenomena; Biochemistry; Countercurrent Distribution; Phenylalanine; Polynucleotides; Research; RNA; RNA, Transfer; Saccharomyces; Saccharomyces cerevisiae; Tyrosine | 1965 |
HYDROXYLATION OF PHENYLALANINE BY PURIFIED PREPARATIONS OF ADRENAL AND BRAIN TYROSINE HYDROXYLASE.
Topics: Adrenal Glands; Amino Acids; Brain; Chromatography; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Hydroxylation; Liver; Mixed Function Oxygenases; Phenylalanine; Research; Tyrosine; Tyrosine 3-Monooxygenase | 1965 |
RAT LIVER ENZYME DOES NOT ACTIVATE ACETYLAMINO ACIDS.
Topics: Acetates; Adenosine Triphosphate; Alanine; Amino Acids; Arginine; Diphosphates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Liver; Lysine; Methionine; Phenylalanine; Proline; Rats; Research; RNA; Serine; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
[STUDIES ON THE AMINO ACID METABOLISM IN LUPUS ERYTHEMATOSUS].
Topics: Biochemical Phenomena; Lupus Erythematosus, Systemic; Metabolism; Phenylalanine; Tyrosine | 1965 |
[L-TYROSINE CONTENT OF THE SERUM OF PATIENTS WITH LUPUS ERYTHEMATOSUS BEFORE AND AFTER ORAL PHENYLALANINE STRESS].
Topics: Blood; Humans; Lupus Erythematosus, Systemic; Phenylalanine; Tyrosine | 1964 |
EFFECT OF AMINO ACIDS ON GROWTH OF SPHAEROTILUS DISCOPHORUS.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Bacteriological Techniques; Caseins; Cystine; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Pharmacology; Phenylalanine; Proline; Research; Serine; Sphaerotilus; Threonine; Tryptophan; Tyrosine; Valine | 1965 |
STUDIES ON HUMAN ANTIBODIES. 3. AMINO ACID COMPOSITION OF FOUR ANTIBODIES FROM ONE INDIVIDUAL.
Topics: Alanine; Amino Acids; Antibodies; Arginine; Aspartic Acid; Chemistry Techniques, Analytical; gamma-Globulins; Glutamates; Glycine; Histidine; Immunochemistry; Immunoglobulins; Isoleucine; Leucine; Lysine; Phenylalanine; Serine; Threonine; Tyrosine; Valine | 1965 |
ALPHA-KETO DERIVATIVES OF AMINO ACIDS AS INHIBITORS OF TRYPSINOGEN ACTIVATION.
Topics: Amino Acids; Arginine; Butyrates; Catalysis; Endopeptidases; Enzyme Inhibitors; Glutamates; Guanidines; Indoleacetic Acids; Indoles; Keto Acids; Ketoglutaric Acids; Leucine; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Research; Trypsinogen; Tryptophan; Tyrosine | 1965 |
STUDIES OF A PHENYLALANINE-TYROSINE REQUIRING MUTANT OF NEUROSPORA CRASSA (STRAIN S 4342).
Topics: Amino Acids; Infrared Rays; Molecular Biology; Mutation; Neurospora; Neurospora crassa; Phenylalanine; Research; Tyrosine | 1965 |
THE BIOSYNTHESIS OF PHENYLALANINE AND TYROSINE; ENZYMES CONVERTING CHORISMIC ACID INTO PREPHENIC ACID AND THEIR RELATIONSHIPS TO PREPHENATE DEHYDRATASE AND PREPHENATE DEHYDROGENASE.
Topics: Benzoates; Chorismic Acid; Chromatography; Cyclohexanecarboxylic Acids; Cyclohexenes; Enterobacter aerogenes; Escherichia coli; Hydro-Lyases; Metabolism; Oxidoreductases; Phenylalanine; Phosphotransferases; Prephenate Dehydratase; Prephenate Dehydrogenase; Research; Spectrophotometry; Tyrosine | 1965 |
RELATION OF BIOCHEMICAL MUTATIONS TO ACTINOMYCIN SYNTHESIS IN STREPTOMYCES ANTIBIOTICUS.
Topics: Adenine; Amino Acids; Arginine; Culture Media; Cysteine; Dactinomycin; Histidine; Isoleucine; Leucine; Metabolism; Methionine; Mutation; Phenylalanine; Research; Streptomyces; Streptomyces antibioticus; Threonine; Tyrosine; Ultraviolet Rays; Uracil; Valine | 1965 |
NEMATODE BIOCHEMISTRY. V. INTERMEDIARY METABOLISM AND AMINO ACID INTERCONVERSIONS IN CAENORHABDITIS BRIGGSAE.
Topics: Acetates; Alanine; Amino Acids; Aminobutyrates; Animals; Asparagine; Aspartic Acid; Bicarbonates; Caenorhabditis; Carbon Dioxide; Chromatography; Formates; Glutamates; Glutamine; Glycine; Malates; Nematoda; Phenylalanine; Research; Serine; Taurine; Tyrosine | 1965 |
CHEMICAL METHOD FOR THE DETECTION OF OVULATION TIME (3).
Topics: Amino Acids; Chemistry Techniques, Analytical; Ovulation; Phenols; Phenylalanine; Rats; Research; Tyramine; Tyrosine; Urine | 1965 |
[CONTRIBUTION TO THE STUDY OF MENTAL DEFICIENCY ETIOLOGY IN CASES OF INBORN ERRORS OF PHENYLALANINE METABOLISM].
Topics: Biochemical Phenomena; Blood; Humans; Intellectual Disability; Phenylalanine; Phenylketonurias; Tyrosine | 1965 |
[DETERMINATION OF PHENYLALANINE AND TYROSINE AFTER OXIDATION WITH POTASSIUM PERMANGANATE].
Topics: Chemistry Techniques, Analytical; Oxidation-Reduction; Phenylalanine; Potassium Permanganate; Research; Tyrosine | 1965 |
BITTER PEPTIDE ISOLATED FROM MILK CULTURES OF STREPTOCOCCUS CREMORIS.
Topics: Alanine; Amino Acids; Arginine; Butanones; Carboxypeptidases; Chemical Phenomena; Chemistry; Chemistry Techniques, Analytical; Chromatography; Culture Media; Electrophoresis; Glutamates; Glycine; Histidine; Indicators and Reagents; Isoleucine; Leucine; Lysine; Metabolism; Methionine; Milk; Peptide Hydrolases; Peptides; Phenylalanine; Proline; Research; Streptococcus; Threonine; Tyrosine; Valine | 1965 |
DETERMINATION OF BACTERIAL DECARBOXYLASES OF SOME AMINO ACIDS BY MEANS OF HIGH VOLTAGE PAPER ELECTROPHORESIS.
Topics: Achromobacter; Amino Acids; Arginine; Aspartic Acid; Bacteria; Carboxy-Lyases; Electrophoresis; Electrophoresis, Paper; Enterobacteriaceae; Escherichia coli; Glutamates; Histidine; Lysine; Ornithine; Phenylalanine; Proteus; Pseudomonas; Serine; Tryptophan; Tyrosine | 1965 |
THE ISOLATION OF AMINO ACIDS FROM MIXTURES AS THEIR N-2,4-DINITROPHENYL DERIVATIVES, METHIONINE, LEUCINE, PHENYLALANINE, ORNITHINE, LYSINE AND TYROSINE.
Topics: Amino Acids; Chromatography; Dinitrophenols; Histidine; Hydrogen-Ion Concentration; Isoleucine; Leucine; Lysine; Methionine; Ornithine; Phenylalanine; Research; Tyrosine; Valine | 1965 |
THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS.
Topics: Amino Acids; Cysteine; Cystine; Glycoproteins; Histidine; Hydrogen-Ion Concentration; Hydroxyproline; Indoles; Isoleucine; Leucine; Methionine; Oxidation-Reduction; Periodic Acid; Phenylalanine; Proline; Pyrroles; Research; Serine; Threonine; Tryptophan; Tyrosine | 1965 |
ENZYMATIC FORMATION OF PHENYLPYRUVIC ACID IN PSEUDOMONAS SP. (ATCC 11299A) AND ITS REGULATION.
Topics: Chemical Phenomena; Chemistry; Enzyme Inhibitors; Enzymes; Hydrogen-Ion Concentration; Phenylalanine; Phenylpyruvic Acids; Pseudomonas; Research; Tyrosine | 1965 |
THE READ-OUT OF TURNIP YELLOW MOSAIC VIRUS RIBONUCLEIC ACID AS A POLYCISTRONIC MESSENGER IN CELL-FREE SYSTEMS OF ESCHERICHIA COLI.
Topics: Cell-Free System; Escherichia coli; Genetic Code; Kinetics; Leucine; Lysine; Methionine; Peptides; Phenylalanine; Plant Viruses; Proteins; Research; Ribosomes; RNA; RNA, Messenger; RNA, Viral; Serine; Threonine; Tymovirus; Tyrosine | 1965 |
The phenylalanine and tyrosine requirements of the rat.
Topics: Animals; Phenylalanine; Rats; Tyrosine | 1955 |
Rat growth experiments with beta-phenylserine diastereoisomers.
Topics: Animals; Biological Phenomena; Growth; Phenylalanine; Physiological Phenomena; Rats; Serine; Tyrosine | 1955 |
Synthesis of tyrosine and phenylalanine by Lactobacillus arabinosus.
Topics: Lactobacillus; Lactobacillus plantarum; Phenylalanine; Tyrosine | 1955 |
The specific amino acid requirements of a human carcinoma cell (Stain HeLa) in tissue culture.
Topics: Amino Acids; Animals; Arginine; Coloring Agents; Female; HeLa Cells; Histidine; Humans; Isoleucine; Leucine; Lysine; Methionine; Mice; Neoplasms, Experimental; Phenylalanine; Threonine; Tissue Culture Techniques; Tryptophan; Tyrosine; Uterine Neoplasms; Uterus; Valine | 1955 |
Studies on the mechanism of the enzymatic conversion of phenylalanine to tyrosine.
Topics: Humans; Phenylalanine; Tyrosine | 1959 |
Nonuniform incorporation of phenylalanine and tyrosine into rabbit hemoglobin in vitro and in vivo.
Topics: Animals; Hemoglobins; In Vitro Techniques; Phenylalanine; Rabbits; Tyrosine | 1960 |
Studies on the dual requirement for phenylalanine and tyrosine in tissue cultures.
Topics: Humans; Phenylalanine; Tissue Culture Techniques; Tyrosine | 1959 |
Intermediary metabolism of phenylalanine and tyrosine in diffuse collagen diseases. II. Influences of the low phenylalanine and tyrosine diet upon patients with collagen disease.
Topics: Collagen; Collagen Diseases; Diet; Humans; Leadership; Phenylalanine; Tyrosine | 1959 |
Nonspecificity of tyrosine transaminase: an explanation for the simultaneous induction of tyrosine, phenylalanine, and tryptophan transaminase activities in rat liver.
Topics: Animals; Liver; Phenylalanine; Rats; Transaminases; Tryptophan Transaminase; Tyrosine; Tyrosine Transaminase | 1962 |
The enzymic conversion of 4-fluorophenylalanine to tyrosine.
Topics: Biochemical Phenomena; p-Fluorophenylalanine; Phenylalanine; Tyrosine | 1961 |
The isolation and characterization of gamma-L-glutamyl-L-tyrosine and gamma-L-glutamyl-L-phenylalanine from soybeans.
Topics: Dipeptides; Glycine max; Phenylalanine; Tyrosine | 1962 |
[Hereditary disorders of the metabolism of phenylalanine, tyrosine and tryptophan].
Topics: Biochemical Phenomena; Humans; Metabolic Diseases; Phenylalanine; Tryptophan; Tyrosine | 1961 |
Reduction of brain dopamine concentration with dietary tyrosine plus phenylalanine depletion: an [11C]raclopride PET study.
Topics: Adult; Beverages; Brain; Carbon Radioisotopes; Corpus Striatum; Dopamine; Humans; Male; Middle Aged; Phenylalanine; Raclopride; Reference Values; Tomography, Emission-Computed; Tyrosine | 2003 |
CU(II)-catalyzed oxidation of Alzheimer's disease beta-amyloid peptide and related sequences: remarkably different selectivities of neurotoxic betaAP1-40 and non-toxic betaAP40-1.
Topics: Amyloid beta-Peptides; Catalysis; Copper; Histidine; Humans; Models, Chemical; Molecular Structure; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2003 |
Contribution of the membrane-distal tyrosine in intracellular signaling by the granulocyte colony-stimulating factor receptor.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Division; Cell Line; Cell Survival; Enzyme Activation; Granulocyte Colony-Stimulating Factor; Humans; Kinetics; Mitogen-Activated Protein Kinases; Peptide Fragments; Phenylalanine; Phosphopeptides; Protein Binding; Receptors, Granulocyte Colony-Stimulating Factor; Recombinant Proteins; Second Messenger Systems; Tyrosine | 2004 |
Decreasing amphetamine-induced dopamine release by acute phenylalanine/tyrosine depletion: A PET/[11C]raclopride study in healthy men.
Topics: Adult; Binding Sites; Brain; Brain Mapping; Dextroamphetamine; Diet, Protein-Restricted; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Male; Phenylalanine; Raclopride; Statistics as Topic; Tomography, Emission-Computed; Tyrosine | 2004 |
Role of the tyrosine corner motif in the stability of neocarzinostatin.
Topics: Amino Acid Motifs; Binding Sites; Calorimetry, Differential Scanning; Circular Dichroism; Hydrogen Bonding; Models, Molecular; Mutation; Phenylalanine; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Temperature; Thermodynamics; Tyrosine; Zinostatin | 2003 |
(De)regulation of key enzyme steps in the shikimate pathway and phenylalanine-specific pathway of the actinomycete Amycolatopsis methanolica.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Actinomyces; Amino Acid Sequence; Aminoacylation; Chorismate Mutase; Enzyme Inhibitors; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Prephenate Dehydratase; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Shikimic Acid; Tyrosine | 2003 |
Correlation of proton release and electrochromic shifts of the optical spectrum due to oxidation of tyrosine in reaction centers from Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Bacteriochlorophylls; Electrochemistry; Electron Spin Resonance Spectroscopy; Histidine; Hydrogen-Ion Concentration; Leucine; Light; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Protons; Rhodobacter sphaeroides; Spectrophotometry; Tyrosine | 2003 |
Additive effects of PDGF receptor beta signaling pathways in vascular smooth muscle cell development.
Topics: Alleles; Animals; Blotting, Southern; Blotting, Western; Cytoplasm; Fibroblasts; Immunohistochemistry; Kidney; Mice; Mice, Transgenic; Models, Genetic; Muscle, Smooth, Vascular; Mutation; Myocytes, Smooth Muscle; Pericytes; Phenylalanine; Point Mutation; Protein Structure, Tertiary; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor beta; Retina; Signal Transduction; Time Factors; Transgenes; Tyrosine | 2003 |
A new method for rapidly and simultaneously decreasing serotonin and catecholamine synthesis in humans.
Topics: Adult; Amino Acids; Brain; Catecholamines; Chromatography, High Pressure Liquid; Diagnostic and Statistical Manual of Mental Disorders; Drug Combinations; Female; Fluorometry; Humans; Male; Mood Disorders; Phenylalanine; Pilot Projects; Serotonin; Time Factors; Tryptophan; Tyrosine | 2003 |
Identification of Tyr413 as an active site residue in the flavoprotein tryptophan 2-monooxygenase and analysis of its contribution to catalysis.
Topics: Alanine; Amino Acid Sequence; Animals; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Conserved Sequence; Flavoproteins; Mixed Function Oxygenases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pseudomonas; Spectrophotometry; Tyrosine; Viper Venoms | 2003 |
HPLC and LC-MS studies of hydroxylation of phenylalanine as an assay for hydroxyl radicals generated from Udenfriend's reagent.
Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Hydroxylation; Indicators and Reagents; Mass Spectrometry; Phenylalanine; Tyrosine | 2003 |
Hydrogen bonding alteration of Thr-204 in the complex between pharaonis phoborhodopsin and its transducer protein.
Topics: Alanine; Amino Acid Substitution; Archaeal Proteins; Carotenoids; Deuterium Oxide; Halorhodopsins; Hydrogen Bonding; Natronobacterium; Phenylalanine; Photoreceptors, Microbial; Sensory Rhodopsins; Serine; Spectroscopy, Fourier Transform Infrared; Threonine; Tyrosine | 2003 |
Meiosis-specific failure of cell cycle progression in fission yeast by mutation of a conserved beta-tubulin residue.
Topics: Amino Acid Sequence; Cell Cycle; Meiosis; Microtubules; Models, Molecular; Molecular Sequence Data; Mutation; Phenylalanine; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Spindle Apparatus; Tubulin; Tyrosine | 2004 |
Simultaneous determination of tyrosine, phenylalanine and deoxyguanosine oxidation products by liquid chromatography-tandem mass spectrometry as non-invasive biomarkers for oxidative damage.
Topics: Calibration; Chromatography, Gas; Chromatography, High Pressure Liquid; Deoxyguanosine; Humans; Mass Spectrometry; Oxidative Stress; Phenylalanine; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2004 |
Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan.
Topics: Amino Acids; Computer Simulation; Cyclotrons; Deuterium; Deuterium Exchange Measurement; Gases; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Phase Transition; Phenylalanine; Proline; Protein Conformation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tryptophan; Tyrosine | 2003 |
A novel competitive ELISA for both free and protein-bound nitrotyrosine.
Topics: Animals; Antibodies, Monoclonal; Binding, Competitive; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Glutaral; Humans; Mice; Peroxynitrous Acid; Phenylalanine; Phosphotyrosine; Protein Binding; Reactive Nitrogen Species; Tyrosine | 2003 |
Solvent and primary deuterium isotope effects show that lactate CH and OH bond cleavages are concerted in Y254F flavocytochrome b2, consistent with a hydride transfer mechanism.
Topics: Catalysis; Deuterium; Deuterium Exchange Measurement; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Hydroxy Acids; Kinetics; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Mutagenesis, Site-Directed; Phenylalanine; Saccharomyces cerevisiae Proteins; Solvents; Tyrosine | 2003 |
Physicochemical features of the HERG channel drug binding site.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Benzopyrans; Binding Sites; Biophysical Phenomena; Biophysics; Cation Transport Proteins; Cisapride; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Inhibitory Concentration 50; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Oocytes; Phenylalanine; Piperidines; Point Mutation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Protein Structure, Tertiary; RNA, Complementary; Sequence Homology, Amino Acid; Serotonin Receptor Agonists; Temperature; Terfenadine; Tyrosine; Xenopus | 2004 |
Tyrosine-to-cysteine modification of human alpha-synuclein enhances protein aggregation and cellular toxicity.
Topics: Adenoviridae; alpha-Synuclein; Animals; Apoptosis; beta-Synuclein; Blotting, Western; Cell Line; Cell Survival; Cloning, Molecular; Cysteine; Detergents; Dimerization; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Magnetic Resonance Spectroscopy; Mice; Microscopy, Fluorescence; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Neurons; Nitrogen; Octoxynol; Oxidative Stress; Oxygen; Phenylalanine; Plasmids; Protein Binding; Proteins; Rats; Recombinant Proteins; Synucleins; Time Factors; Transfection; Tyrosine | 2004 |
NKp44 triggers NK cell activation through DAP12 association that is not influenced by a putative cytoplasmic inhibitory sequence.
Topics: Adaptor Protein Complex 2; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acid Substitution; Cell Line, Tumor; Cell Membrane; Cytoplasm; Cytotoxicity, Immunologic; Humans; Jurkat Cells; Killer Cells, Natural; Lymphocyte Activation; Lysine; Membrane Proteins; Molecular Sequence Data; Natural Cytotoxicity Triggering Receptor 2; Peptide Fragments; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Receptors, Immunologic; Tyrosine | 2004 |
Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition.
Topics: Amino Acid Sequence; Deuterium; Linear Models; Mass Spectrometry; Peptides; Phenylalanine; Reproducibility of Results; Silicon; Thymopentin; Tyrosine | 2003 |
A monomer form of the glutathione S-transferase Y7F mutant from Schistosoma japonicum at acidic pH.
Topics: Animals; Calorimetry; Chromatography, Gel; Dimerization; Electrophoresis; Enzyme Activation; Enzyme Stability; Glutathione; Hydrogen-Ion Concentration; Isoenzymes; Mutation; Phenylalanine; Protein Denaturation; Protein Folding; Schistosoma japonicum; Spectrometry, Fluorescence; Structure-Activity Relationship; Substrate Specificity; Tyrosine; Urea | 2004 |
Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.
Topics: Adenosine Deaminase; Amino Acid Substitution; Animals; Binding, Competitive; Blood Glucose; Cell Line, Tumor; Cricetinae; Cyclic AMP; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Fibroblasts; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glutamine; Glycoproteins; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Obese; Peptide Fragments; Phenylalanine; Proline; Protein Precursors; Rats; Receptors, Glucagon; Spectrometry, Mass, Electrospray Ionization; Transformation, Genetic; Tyrosine | 2003 |
Disruption of Ca2+-dependent cell-matrix adhesion enhances c-Src kinase activity, but causes dissociation of the c-Src/FAK complex and dephosphorylation of tyrosine-577 of FAK in carcinoma cells.
Topics: Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma; Cell Line, Tumor; Cell-Matrix Junctions; CSK Tyrosine-Protein Kinase; Enzyme Activation; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Mammary Neoplasms, Animal; Mice; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; src Homology Domains; src-Family Kinases; Tyrosine | 2004 |
Role of Phe283 in enzymatic reaction of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp.1011: Substrate binding and arrangement of the catalytic site.
Topics: Acarbose; Bacillus; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Glucosyltransferases; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutation; Phenylalanine; Pliability; Protein Structure, Tertiary; Substrate Specificity; Tyrosine | 2004 |
Proteolysis on Reggianito Argentino cheeses manufactured with natural whey cultures and selected strains of Lactobacillus helveticus.
Topics: Amino Acids; Argentina; Cheese; Chromatography, High Pressure Liquid; Food Technology; Lactobacillus; Milk Proteins; Peptide Hydrolases; Phenylalanine; Time Factors; Tryptophan; Tyrosine; Whey Proteins | 2003 |
Crystals of the ribonucleotide reductase R2 protein from Chlamydia trachomatis obtained by heavy-atom co-crystallization.
Topics: Binding Sites; Chlamydia trachomatis; Cloning, Molecular; Crystallization; Crystallography, X-Ray; Phenylalanine; Protein Structure, Tertiary; Ribonucleotide Reductases; Tyrosine | 2004 |
2',6'-dimethylphenylalanine (Dmp) can mimic the N-terminal Tyr in opioid peptides.
Topics: Animals; Enkephalin, Leucine; Guinea Pigs; Ileum; In Vitro Techniques; Ligands; Male; Mice; Molecular Mimicry; Muscle Contraction; Muscle, Smooth; Oligopeptides; Opioid Peptides; Phenylalanine; Radioligand Assay; Receptors, Opioid, delta; Tyrosine; Vas Deferens | 2004 |
Effects of essential carbohydrate/aromatic stacking interaction with Tyr100 and Phe259 on substrate binding of cyclodextrin glycosyltransferase from alkalophilic Bacillus sp. 1011.
Topics: Acarbose; Amino Acid Sequence; Bacillus; Binding Sites; Crystallography, X-Ray; Glucosyltransferases; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligosaccharides; Phenylalanine; Protein Binding; Structure-Activity Relationship; Substrate Specificity; Tyrosine | 2003 |
The metabolism of phenylalanine and tyrosine in mutant strains of Escherichia coli.
Topics: Escherichia coli; Phenylalanine; Tyrosine | 1950 |
Non-enzymatic oxidation of tyrosine and dopa.
Topics: Dihydroxyphenylalanine; Oxidation-Reduction; Phenylalanine; Tyrosine | 1950 |
Effect of ACTH and some adrenocortical steroids on the metabolism of tyrosine and phenylalanine in premature infants.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Humans; Infant, Newborn; Infant, Premature; Phenylalanine; Tyrosine | 1951 |
The enzymatic conversion of phenylalanine to tyrosine.
Topics: Phenylalanine; Tyrosine | 1952 |
ENZYMATIC conversion of phenylalanine to tyrosine.
Topics: Humans; Phenylalanine; Tyrosine | 1952 |
Phe393 mutants of cytochrome P450 BM3 with modified heme redox potentials have altered heme vinyl and propionate conformations.
Topics: Amino Acid Substitution; Bacillus megaterium; Bacterial Proteins; Cytochrome P-450 Enzyme System; Ferric Compounds; Ferrous Compounds; Heme; Iron-Sulfur Proteins; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phenylalanine; Propionates; Protein Conformation; Protein Structure, Tertiary; Spectrum Analysis, Raman; Substrate Specificity; Tryptophan; Tyrosine; Vinyl Compounds | 2004 |
Role of active-site residues Thr81, Ser82, Thr85, Gln157, and Tyr158 in yeast cystathionine beta-synthase catalysis and reaction specificity.
Topics: Alanine; Amino Acid Substitution; Binding Sites; Catalysis; Chromatography, Affinity; Cystathionine beta-Synthase; Glutamine; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Nickel; Phenylalanine; Pyruvic Acid; Saccharomyces cerevisiae Proteins; Serine; Substrate Specificity; Threonine; Tyrosine | 2004 |
The role of Tyr41 and His155 in the functional properties of superoxide dismutase from the archaeon Sulfolobus solfataricus.
Topics: Amino Acid Substitution; Archaeal Proteins; Crystallization; Crystallography, X-Ray; Enzyme Activation; Enzyme Inhibitors; Enzyme Stability; Glutamine; Histidine; Hot Temperature; Phenylalanine; Protein Denaturation; Recombinant Proteins; Sodium Dodecyl Sulfate; Sulfolobus; Superoxide Dismutase; Tyrosine | 2004 |
Resonance Raman spectroscopy reveals the origin of an intermediate wavelength form in photoactive yellow protein.
Topics: Alanine; Amino Acid Substitution; Bacterial Proteins; Deuterium Exchange Measurement; Glutamic Acid; Glutamine; Kinetics; Phenylalanine; Photoreceptors, Microbial; Quantum Theory; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Thermodynamics; Thiocyanates; Threonine; Tyrosine; Valine | 2004 |
Shortened insulin analogues: marked changes in biological activity resulting from replacement of TyrB26 and N-methylation of peptide bonds in the C-terminus of the B-chain.
Topics: Amino Acid Substitution; Animals; Biological Transport; Deoxyglucose; Humans; Hydrogen Bonding; Insulin; Male; Methylation; Peptide Fragments; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Rats; Rats, Wistar; Receptor, Insulin; Recombinant Proteins; Swine; Tyrosine | 2004 |
Oxidative damage to proteins in yeast cells exposed to adaptive levels of H(2)O(2).
Topics: Antioxidants; Calibration; Cell Division; Dose-Response Relationship, Drug; Free Radicals; Gas Chromatography-Mass Spectrometry; Glutathione; Hydrogen Peroxide; Mass Spectrometry; Mutation; Oxidative Stress; Oxygen; Phenylalanine; Saccharomyces cerevisiae; Time Factors; Tyrosine | 2003 |
Variable contributions of tyrosine residues to the structural and spectroscopic properties of the factor for inversion stimulation.
Topics: Amino Acid Sequence; Circular Dichroism; DNA-Binding Proteins; Factor For Inversion Stimulation Protein; Fluorescence Polarization; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Denaturation; Protein Folding; Sequence Alignment; Serine Endopeptidases; Spectrometry, Fluorescence; Trypsin; Tyrosine; Urea | 2004 |
Kinetics of factor Xa inhibition by recombinant tick anticoagulant peptide: both active site and exosite interactions are required for a slow- and tight-binding inhibition mechanism.
Topics: 1-Carboxyglutamic Acid; Anticoagulants; Arginine; Arthropod Proteins; Binding Sites; Binding, Competitive; Cell Line; Factor Xa; Factor Xa Inhibitors; Humans; Intercellular Signaling Peptides and Proteins; Kinetics; Mutagenesis, Site-Directed; Ornithodoros; Peptides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Serine Proteinase Inhibitors; Tyrosine | 2004 |
Regio- and stereo-chemical oxidation of linoleic acid by human myoglobin and hydrogen peroxide: Tyr(103) affects rate and product distribution.
Topics: Animals; Humans; Hydrogen Peroxide; Linoleic Acid; Lipid Peroxidation; Myoglobin; Oxidation-Reduction; Phenylalanine; Recombinant Proteins; Stereoisomerism; Tyrosine; Whales | 2004 |
Aromatic amino acid aminotransferase activity and indole-3-acetic acid production by associative nitrogen-fixing bacteria.
Topics: Azospirillum; Electrophoresis, Polyacrylamide Gel; Enzyme Stability; Gluconacetobacter; Histidine; Indoleacetic Acids; Molecular Weight; Nitrogen Fixation; Phenylalanine; Plant Growth Regulators; Pseudomonas stutzeri; Substrate Specificity; Transaminases; Tryptophan; Tyrosine | 2004 |
Rescue of protein splicing activity from a Magnetospirillum magnetotacticum intein-like element.
Topics: Alanine; Alternative Splicing; Catalysis; Cysteine; Magnetospirillum; Models, Genetic; Mutation; Phenylalanine; Polymorphism, Genetic; Protein Splicing; Protein Structure, Tertiary; RNA Splicing; Serine; Tyrosine | 2004 |
Mode of action of the TyrR protein: repression and activation of the tyrP promoter of Escherichia coli.
Topics: Amino Acid Transport Systems, Neutral; Artificial Gene Fusion; Base Sequence; beta-Galactosidase; Carrier Proteins; DNA Footprinting; DNA-Binding Proteins; DNA-Directed RNA Polymerases; DNA, Superhelical; Electrophoretic Mobility Shift Assay; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Genes, Reporter; Molecular Sequence Data; Nucleic Acid Conformation; Phenylalanine; Point Mutation; Promoter Regions, Genetic; Protein Subunits; Repressor Proteins; Transcription, Genetic; Tyrosine | 2004 |
Selectivity control in the separation of aromatic amino acid enantiomers with sulphated beta-cyclodextrin.
Topics: Amino Acids, Aromatic; beta-Cyclodextrins; Cyclodextrins; Electrophoresis, Capillary; Indicators and Reagents; Neural Networks, Computer; Phenylalanine; Spectrophotometry, Ultraviolet; Stereoisomerism; Temperature; Tryptophan; Tyrosine | 2004 |
Neuroprotective action of halogenated derivatives of L-phenylalanine.
Topics: Animals; Disease Models, Animal; In Vitro Techniques; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Male; Neurons; Neuroprotective Agents; Patch-Clamp Techniques; Phenylalanine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Stroke; Synaptic Transmission; Tyrosine | 2004 |
Substitution of the conserved Arg-Tyr dyad selectively disrupts the hydrolysis phase of the IMP dehydrogenase reaction.
Topics: Adenosine Diphosphate; Alanine; Amino Acid Substitution; Animals; Arginine; Binding Sites; Cattle; Conserved Sequence; Deuterium Exchange Measurement; Enzyme Inhibitors; Hydrolysis; IMP Dehydrogenase; Kinetics; Mutagenesis, Site-Directed; Mycophenolic Acid; Phenylalanine; Point Mutation; Protein Binding; Ribavirin; Ribonucleosides; Ribonucleotides; Solvents; Substrate Specificity; Tritrichomonas foetus; Tyrosine; Xanthine | 2004 |
Autoreduction of ferryl myoglobin: discrimination among the three tyrosine and two tryptophan residues as electron donors.
Topics: Animals; Cross-Linking Reagents; Dimerization; Electron Transport; Hydrogen Peroxide; Metmyoglobin; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Recombinant Proteins; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine; Whales | 2004 |
Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
Topics: Amino Acid Substitution; Animals; Antigen Presentation; Antigens, Viral; Crystallography, X-Ray; Epitopes, T-Lymphocyte; Glycoproteins; H-2 Antigens; Leucine; Lymphocytic choriomeningitis virus; Mice; Peptide Fragments; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Receptors, Antigen, T-Cell; Structure-Activity Relationship; T-Lymphocytes, Cytotoxic; Tyrosine; Valine; Viral Proteins | 2004 |
Regulation of ubiquitin protein ligase activity in c-Cbl by phosphorylation-induced conformational change and constitutive activation by tyrosine to glutamate point mutations.
Topics: Cell Line; Down-Regulation; Electrophoresis, Polyacrylamide Gel; ErbB Receptors; Gene Expression Regulation, Enzymologic; Glutamic Acid; Glutathione Transferase; Humans; Mutation; Phenylalanine; Phosphorylation; Point Mutation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Tyrosine; Ubiquitin-Protein Ligases | 2004 |
Direct probing of copper active site and free radical formed during bicarbonate-dependent peroxidase activity of bovine and human copper, zinc-superoxide dismutases. Low-temperature electron paramagnetic resonance and electron nuclear double resonance stu
Topics: Animals; Bicarbonates; Binding Sites; Cattle; Copper; Electron Spin Resonance Spectroscopy; Free Radicals; Histidine; Humans; Hydrogen Peroxide; Magnetics; Models, Chemical; Models, Molecular; Models, Statistical; Mutation; Oxygen; Phenylalanine; Protons; Spectrophotometry; Superoxide Dismutase; Time Factors; Tryptophan; Tyrosine; Ultraviolet Rays | 2004 |
Lidoflazine is a high affinity blocker of the HERG K(+)channel.
Topics: Cell Line; Electrophysiology; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Lidoflazine; Mutation; Phenylalanine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Tyrosine | 2004 |
Assessment of the neurologic effects of dietary deficiencies of phenylalanine and tyrosine in cats.
Topics: Amino Acids, Essential; Animal Nutritional Physiological Phenomena; Animals; Cat Diseases; Cats; Electromyography; Hair Color; Microscopy, Electron, Scanning; Muscle, Skeletal; Neural Conduction; Neurodegenerative Diseases; Nutritional Requirements; Peroneal Nerve; Phenylalanine; Tyrosine | 2004 |
Prevalence of stimulant use for attentional dysfunction in children with phenylketonuria.
Topics: Adolescent; Attention; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Female; Humans; Male; Phenylalanine; Phenylketonurias; Prevalence; Retrospective Studies; Tyrosine | 2004 |
Tetrahydrobiopterin deficiency and dopamine loss in a genetic mouse model of Lesch-Nyhan disease.
Topics: Animals; Biopterins; Corpus Striatum; Disease Models, Animal; Dopamine; Dopamine Agents; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Levodopa; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenylalanine; Tyrosine | 2004 |
Cysteine-scanning mutagenesis and thiol modification of the Rickettsia prowazekii ATP/ADP translocase: evidence that transmembrane regions I and II, but not III, are structural components of the aqueous translocation channel.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cysteine; Ethyl Methanesulfonate; Ion Channel Gating; Isoleucine; Mesylates; Mitochondrial ADP, ATP Translocases; Molecular Sequence Data; Mutagenesis; Mutation; Phenylalanine; Rickettsia prowazekii; Sequence Homology, Amino Acid; Sulfhydryl Compounds; Translocation, Genetic; Tyrosine | 2004 |
Phosphorylation and recruitment of Syk by immunoreceptor tyrosine-based activation motif-based phosphorylation of tamalin.
Topics: Alternative Splicing; Amino Acid Motifs; Animals; Brain; Carrier Proteins; Cell Line; Cell Membrane; COS Cells; CSK Tyrosine-Protein Kinase; DNA; DNA Mutational Analysis; DNA, Complementary; Enzyme Precursors; Immunoblotting; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Models, Genetic; Mutation; Phenylalanine; Phosphorylation; Precipitin Tests; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Rats; Signal Transduction; src-Family Kinases; Syk Kinase; Transfection; Tretinoin; Tyrosine | 2004 |
(4-Carboxamido)phenylalanine is a surrogate for tyrosine in opioid receptor peptide ligands.
Topics: Amino Acids, Aromatic; Analgesics, Opioid; Binding Sites; Cell Line; Humans; Ligands; Molecular Structure; Opioid Peptides; Phenol; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tyrosine | 2004 |
Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding.
Topics: Amino Acid Substitution; Animals; Cell Line; DNA-Binding Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Mice; NIH 3T3 Cells; Phenylalanine; Phosphoproteins; Plasmids; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; ras GTPase-Activating Proteins; RNA-Binding Proteins; Signal Transduction; Transformation, Genetic; Tyrosine | 2004 |
Role of Phe308 in the seventh transmembrane domain of the AT2 receptor in ligand binding and signaling.
Topics: Amino Acid Sequence; Angiotensin II; Animals; Cyclic CMP; Humans; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rats; Receptor, Angiotensin, Type 2; Signal Transduction; Tyrosine; Xenopus | 2004 |
Contribution of Tyr712 and Phe716 to the activity of human RNase L.
Topics: Amino Acid Sequence; Base Sequence; Catalysis; DNA Primers; Endoribonucleases; Humans; Kinetics; Molecular Sequence Data; Phenylalanine; Plasmids; Sequence Homology, Amino Acid; Tyrosine | 2004 |
c-Cbl-mediated ubiquitinylation is required for epidermal growth factor receptor exit from the early endosomes.
Topics: Animals; Blotting, Western; Cell Line, Tumor; CHO Cells; Cricetinae; Down-Regulation; Endosomes; ErbB Receptors; Humans; Hydrogen Peroxide; Microscopy, Fluorescence; Models, Biological; Mutation; Oxidative Stress; Phenylalanine; Phosphoprotein Phosphatases; Precipitin Tests; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; RNA Processing, Post-Transcriptional; Signal Transduction; Transfection; Tyrosine; Ubiquitin; Ubiquitin-Protein Ligases | 2004 |
Subsets of the major tyrosine phosphorylation sites in Crk-associated substrate (CAS) are sufficient to promote cell migration.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Binding Sites; Cell Movement; COS Cells; Crk-Associated Substrate Protein; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptide Mapping; Peptides; Phenylalanine; Phosphorylation; Plasmids; Protein Binding; Protein Structure, Tertiary; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; src Homology Domains; Trypsin; Tyrosine; Wound Healing | 2004 |
Diffuse pharmacophoric domains of vasoactive intestinal peptide (VIP) and further insights into the interaction of VIP with the N-terminal ectodomain of human VPAC1 receptor by photoaffinity labeling with [Bpa6]-VIP.
Topics: Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Cell Membrane; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Electrophoresis; Humans; Kinetics; Ligands; Light; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phenylalanine; Photoaffinity Labels; Protein Binding; Protein Structure, Tertiary; Receptors, Vasoactive Intestinal Peptide; Receptors, Vasoactive Intestinal Polypeptide, Type I; Recombinant Proteins; Trypsin; Tyrosine; Vasoactive Intestinal Peptide | 2004 |
Amino acid contents along the visual and equatorial axes of a pig lens by Raman spectroscopy.
Topics: Amino Acids; Animals; Lasers; Lens, Crystalline; Male; Phenylalanine; Refractometry; Spectrum Analysis, Raman; Swine; Tryptophan; Tyrosine | 2004 |
The homogentisate pathway: a central catabolic pathway involved in the degradation of L-phenylalanine, L-tyrosine, and 3-hydroxyphenylacetate in Pseudomonas putida.
Topics: Bacterial Proteins; Base Sequence; Biodegradation, Environmental; Gene Expression Regulation, Bacterial; Homogentisic Acid; Molecular Sequence Data; Multigene Family; Phenylacetates; Phenylalanine; Pseudomonas putida; Sequence Analysis, DNA; Tyrosine | 2004 |
Structural determinants of HERG channel block by clofilium and ibutilide.
Topics: Amino Acid Substitution; Animals; Anti-Arrhythmia Agents; Aspartic Acid; Benzopyrans; Binding Sites; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Oocytes; Phenethylamines; Phenylalanine; Piperidines; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Pyridines; Quaternary Ammonium Compounds; Serine; Sulfonamides; Tyrosine; Xenopus laevis | 2004 |
Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.
Topics: Animals; Cell Line; Chlorocebus aethiops; Endocytosis; ErbB Receptors; Humans; Insulin-Like Growth Factor I; Metalloendopeptidases; Mice; Mitogen-Activated Protein Kinase 3; Paracrine Communication; Phenylalanine; Phosphorylation; Quinazolines; Rats; Receptors, Somatomedin; Tetradecanoylphorbol Acetate; Thiophenes; Tyrosine; Tyrphostins | 2004 |
Redox characterization of Geobacter sulfurreducens cytochrome c7: physiological relevance of the conserved residue F15 probed by site-specific mutagenesis.
Topics: Amino Acid Substitution; Bacterial Proteins; Conserved Sequence; Cytochrome c Group; Desulfuromonas; Geobacter; Heme; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenylalanine; Protons; Spectrophotometry, Ultraviolet; Thermodynamics; Tyrosine | 2004 |
Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Allosteric Regulation; Binding Sites; Cadmium; Crystallography, X-Ray; Feedback, Physiological; Phenylalanine; Phosphoenolpyruvate; Protein Conformation; Protein Subunits; Sugar Phosphates; Thermotoga maritima; Tyrosine | 2004 |
Glycosaminoglycan disaccharide alters the dimer dissociation constant of the chemokine MIP-1 beta.
Topics: Amino Acid Substitution; Animals; Chemokine CCL4; Chemokine CCL5; Dimerization; Disaccharides; Heparin; Humans; Leucine; Macaca mulatta; Macrophage Inflammatory Proteins; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Binding; Receptors, CCR5; Tyrosine; Ultracentrifugation | 2004 |
A microplate-based enzymatic assay for the simultaneous determination of phenylalanine and tyrosine in serum.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cinnamates; Coumarins; Humans; Indicators and Reagents; Linear Models; Phenylalanine; Phenylalanine Ammonia-Lyase; Phenylketonurias; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet; Tyrosine | 2004 |
Human phenylalanine hydroxylase is activated by H2O2: a novel mechanism for increasing the L-tyrosine supply for melanogenesis in melanocytes.
Topics: Cell Division; Enzyme Activation; Humans; Hydrogen Peroxide; Melanins; Melanocytes; Models, Molecular; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Protein Conformation; Tyrosine; Ultraviolet Rays | 2004 |
Roles of noncoordinated aromatic residues in redox regulation of cytochrome c3 from Desulfovibrio vulgaris Miyazaki F.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Cytochrome c Group; Desulfovibrio vulgaris; Electrochemistry; Heme; Histidine; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Phenylalanine; Tyrosine | 2004 |
First-principles calculations of protein circular dichroism in the near ultraviolet.
Topics: Amino Acid Sequence; Amino Acids, Aromatic; Animals; Aprotinin; Bacterial Proteins; Carbonic Anhydrase II; Cattle; Circular Dichroism; Computational Biology; Humans; Mutation; Phenylalanine; Proteins; Ribonucleases; Static Electricity; Tryptophan; Tyrosine; Ultraviolet Rays | 2004 |
Iron-binding process in the amino- and carboxyl-terminal lobes of ovotransferrin: quantitative studies utilizing single Fe3+-binding mutants.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Calorimetry, Differential Scanning; Chickens; Conalbumin; Ferric Compounds; Iron-Binding Proteins; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Pichia; Protein Binding; Protein Denaturation; Thermodynamics; Tyrosine | 2004 |
Src tyrosine kinase inhibitor PP2 markedly enhances Ras-independent activation of Raf-1 protein kinase by phorbol myristate acetate and H2O2.
Topics: Animals; Binding Sites; Cell Line, Transformed; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Epitopes; Genes, Dominant; Hydrogen Peroxide; Immunoblotting; Immunoprecipitation; Mice; Models, Biological; NIH 3T3 Cells; Phenylalanine; Phosphorylation; Plasmids; Point Mutation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-raf; Pyrimidines; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tyrosine | 2004 |
Acetylcholine binding site in the vesicular acetylcholine transporter.
Topics: Acetylcholine; Alanine; Allosteric Site; Animals; Binding Sites; Membrane Transport Proteins; Mutagenesis, Site-Directed; PC12 Cells; Phenylalanine; Piperidines; Protein Transport; Rats; Subcellular Fractions; Synaptic Vesicles; Transfection; Tritium; Tyrosine; Vesicular Acetylcholine Transport Proteins; Vesicular Transport Proteins | 2004 |
Determination of phenylalanine and tyrosine in dried blood specimens by ion-exchange chromatography using the Hitachi L-8800 analyzer.
Topics: Blood Specimen Collection; Case-Control Studies; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Humans; Phenylalanine; Phenylketonurias; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2004 |
On the metabolism of phenylalanine and tyrosine.
Topics: Phenylalanine; Tyrosine | 1949 |
Metabolism of C14-labeled tyrosine and phenylalanine in phlorizinized rats.
Topics: Animals; Phenylalanine; Rats; Tyrosine | 1950 |
The concentration of tryptophan; cystine, tyrosine, phenylalanine, histidine and methionine in normal human urine-microbiological assay.
Topics: Amino Acids; Cystine; Histidine; Methionine; Phenylalanine; Tryptophan; Tyrosine; Urine | 1950 |
Engineering of the pH optimum of Bacillus cereus beta-amylase: conversion of the pH optimum from a bacterial type to a higher-plant type.
Topics: Asparagine; Bacillus cereus; Bacterial Proteins; beta-Amylase; Binding Sites; Crystallography, X-Ray; Enzyme Activation; Glutamic Acid; Glycine max; Hydrogen-Ion Concentration; Kinetics; Maltose; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Plant Proteins; Threonine; Tyrosine | 2004 |
Hydroxyl radical oxidation of cytochrome c by aerobic radiolysis.
Topics: Aerobiosis; Amino Acid Sequence; Animals; Cytochromes c; Dose-Response Relationship, Radiation; Electrons; Heme; Horses; Hydroxyl Radical; Hydroxylation; Intracellular Membranes; Methionine; Mitochondria, Heart; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Protein Conformation; Pulse Radiolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tyrosine | 2004 |
Phenylalanine hydroxylase deficiency in the peripheral lymphocytes from phenylketonuria.
Topics: Autoradiography; Case-Control Studies; Cells, Cultured; Female; Humans; Japan; Lymphocytes; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Reference Values; Sampling Studies; Sensitivity and Specificity; Tyrosine | 1977 |
Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin. Insights into molecular coevolution of V1a type receptors and their ligands.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arginine Vasopressin; Binding Sites; Gene Expression; Genes, fos; Humans; Isoleucine; Models, Molecular; Molecular Sequence Data; Mutagenesis; Phenylalanine; Proline; Promoter Regions, Genetic; Rana catesbeiana; Rats; Receptors, Vasopressin; Recombinant Fusion Proteins; Structure-Activity Relationship; Threonine; Transfection; Tyrosine; Vasotocin | 2004 |
Substrate regulation of serotonin and dopamine synthesis in Drosophila.
Topics: Animals; Biopterins; Blotting, Western; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dose-Response Relationship, Drug; Drosophila; Drosophila Proteins; Electrophoresis, Gel, Two-Dimensional; Immunoprecipitation; Iron; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Recombinant Fusion Proteins; Serotonin; Substrate Specificity; Time Factors; Tryptophan; Tryptophan Hydroxylase; Tyrosine | 2004 |
Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.
Topics: Asparagine; Binding Sites; Camptothecin; Conserved Sequence; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Enzyme Inhibitors; Histidine; Mutagenesis; Phenylalanine; Saccharomyces cerevisiae; Structure-Activity Relationship; Tyrosine | 2004 |
Site-directed mutagenesis of Thermosynechococcus elongatus photosystem II: the O2-evolving enzyme lacking the redox-active tyrosine D.
Topics: Amino Acid Substitution; Bacterial Proteins; Chlorophyll; Cyanobacteria; Electron Spin Resonance Spectroscopy; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Phenylalanine; Photolysis; Photosystem II Protein Complex; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2004 |
Importance of exposed aromatic residues in chitinase B from Serratia marcescens 2170 for crystalline chitin hydrolysis.
Topics: Catalysis; Chitin; Chitinases; DNA Primers; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Microfibrils; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Serratia marcescens; Time Factors; Tryptophan; Tyrosine | 2004 |
Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine.
Topics: Animals; Carbocysteine; Coenzymes; Cytosol; Deferoxamine; Female; Iron Chelating Agents; Liver; Methionine; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Wistar; Substrate Specificity; Tyrosine | 2004 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
Cation-pi interactions: structures and energetics of complexation of Na+ and K+ with the aromatic amino acids, phenylalanine, tyrosine, and tryptophan.
Topics: Cations, Monovalent; Models, Molecular; Phenylalanine; Potassium; Sodium; Thermodynamics; Tryptophan; Tyrosine | 2004 |
Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase.
Topics: Escherichia coli; Hydrolysis; Models, Molecular; Mutation; Phenylalanine; Phenylalanine-tRNA Ligase; Plasmids; Protein Biosynthesis; Protein Subunits; RNA, Transfer, Phe; Tyrosine; Tyrosine-tRNA Ligase | 2004 |
Trapped tyrosyl radical populations in modified reaction centers from Rhodobacter sphaeroides.
Topics: Amino Acid Substitution; Darkness; Electron Spin Resonance Spectroscopy; Free Radicals; Glutamic Acid; Light; Phenylalanine; Photosynthetic Reaction Center Complex Proteins; Rhodobacter sphaeroides; Tyrosine | 2004 |
Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions.
Topics: Amino Acid Substitution; Amyloid; Animals; Cell Line; Cell Survival; Diabetes Mellitus, Type 2; Flavonoids; Growth Inhibitors; Humans; Islet Amyloid Polypeptide; Islets of Langerhans; Mice; PC12 Cells; Peptide Fragments; Phenols; Phenolsulfonphthalein; Phenylalanine; Polyphenols; Protein Binding; Protein Interaction Mapping; Rats; Spectrometry, Fluorescence; Tyrosine | 2004 |
Tyr204Phe and Val34Leu polymorphisms in two Brazilian ethnic groups and in patients with recurrent miscarriages.
Topics: Abortion, Habitual; Black People; Brazil; Factor XIII; Female; Humans; Leucine; Male; Phenylalanine; Polymorphism, Genetic; Pregnancy; Tyrosine; Valine; White People | 2004 |
Phenylalanine loading as a diagnostic test for DRD: interpreting the utility of the test.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; DNA Mutational Analysis; DNA Primers; Dystonic Disorders; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Pedigree; Phenylalanine; Phenylalanine Hydroxylase; Sequence Analysis, DNA; Time Factors; Tyrosine | 2004 |
Oxygen reactions in p-hydroxybenzoate hydroxylase utilize the H-bond network during catalysis.
Topics: 4-Hydroxybenzoate-3-Monooxygenase; Amino Acid Substitution; Catalysis; Glutamic Acid; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxylation; Lysine; Methionine; Oxidation-Reduction; Phenylalanine; Pseudomonas aeruginosa; Pseudomonas fluorescens; Tyrosine | 2004 |
Requirements for pYXXM motifs in Cbl for binding to the p85 subunit of phosphatidylinositol 3-kinase and Crk, and activation of atypical protein kinase C and glucose transport during insulin action in 3T3/L1 adipocytes.
Topics: 3T3-L1 Cells; Amino Acid Motifs; Animals; Biological Transport; Cell Membrane; Glucose; Humans; Insulin; Insulin Antagonists; Insulin Receptor Substrate Proteins; Isoenzymes; Mice; Oncogene Protein v-cbl; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Subunits; Protein Transport; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Retroviridae Proteins, Oncogenic; Tyrosine | 2004 |
In vitro and in vivo analyses of a Phe/Tyr switch controlling product specificity of histone lysine methyltransferases.
Topics: Amino Acid Sequence; Animals; Catalysis; DNA Methylation; Gene Silencing; Histone-Lysine N-Methyltransferase; Histones; Humans; Kinetics; Mass Spectrometry; Methylation; Mice; Molecular Sequence Data; Mutation; Neurospora crassa; Phenylalanine; Stem Cells; Substrate Specificity; Tyrosine | 2005 |
An ultraviolet fluorescence-based method for identifying and distinguishing protein crystals.
Topics: Aldose-Ketose Isomerases; Animals; Chickens; Crystallography, X-Ray; Humans; Hydrogen-Ion Concentration; Microscopy, Fluorescence; Models, Theoretical; Muramidase; Phenylalanine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proteins; Salts; Temperature; Tryptophan; Tyrosine; Ultraviolet Rays | 2005 |
Conservation of cis prolyl bonds in proteins during evolution.
Topics: Amino Acids; Animals; Area Under Curve; Biological Evolution; Conserved Sequence; Humans; Models, Chemical; Molecular Conformation; Peptides; Phenylalanine; Proline; Protein Binding; Protein Conformation; Proteins; Proteomics; Tryptophan; Tyrosine | 2005 |
Toward the insulin-IGF-I intermediate structures: functional and structural properties of the [TyrB25NMePheB26] insulin mutant.
Topics: Animals; Dimerization; Humans; Insulin; Insulin-Like Growth Factor I; Methylation; Models, Molecular; Molecular Sequence Data; Mutation; Peptide Fragments; Phenylalanine; Protein Structure, Tertiary; Swine; Tyrosine | 2004 |
Site-specific replacement of a conserved tyrosine in ribonucleotide reductase with an aniline amino acid: a mechanistic probe for a redox-active tyrosine.
Topics: Hydrogen Bonding; Models, Molecular; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Protons; Ribonucleotide Reductases; Tyrosine | 2004 |
Proteasome activity is altered in skeletal muscle tissue of tumour-bearing rats a leucine-rich diet.
Topics: Animals; Carcinoma 256, Walker; Dietary Supplements; Electrophoresis, Polyacrylamide Gel; Female; Leucine; Muscle, Skeletal; Myosin Heavy Chains; Phenylalanine; Pregnancy; Pregnancy Complications, Neoplastic; Proteasome Endopeptidase Complex; Protein Biosynthesis; Rats; Rats, Wistar; Tumor Cells, Cultured; Tyrosine; Ubiquitin | 2004 |
Purification, characterization cloning, and sequencing of metalloendopeptidase from Streptomyces septatus TH-2.
Topics: Amino Acid Motifs; Amino Acid Sequence; Bacillus; Base Sequence; Binding Sites; Culture Media; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Fluorescence Resonance Energy Transfer; Glucose; Glycopeptides; Hydrogen-Ion Concentration; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Phenylalanine; Polymerase Chain Reaction; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry, Atomic; Streptomyces; Streptomyces griseus; Substrate Specificity; Temperature; Thermolysin; Tyrosine; Zinc | 2005 |
Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
Topics: Calorimetry, Differential Scanning; Crystallography, X-Ray; Hot Temperature; Humans; Hydrophobic and Hydrophilic Interactions; Interleukin-1; Models, Molecular; Mutation; Phenylalanine; Protein Folding; Protein Structure, Tertiary; Solubility; Solvents; Thermodynamics; Tyrosine | 2005 |
Crystallographic and thermodynamic analysis of the binding of S-octylglutathione to the Tyr 7 to Phe mutant of glutathione S-transferase from Schistosoma japonicum.
Topics: Animals; Binding, Competitive; Calorimetry; Crystallization; Crystallography, X-Ray; Enzyme Inhibitors; Glutathione; Glutathione Transferase; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Subunits; Schistosoma japonicum; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics; Tyrosine | 2005 |
Identification of residues that contribute to receptor activation through the analysis of compensatory mutations in the G protein-coupled alpha-factor receptor.
Topics: Alanine; Amino Acid Sequence; Cysteine; DNA Mutational Analysis; Genes, Suppressor; Genetic Testing; Mating Factor; Molecular Sequence Data; Mutagenesis; Peptides; Phenylalanine; Receptors, G-Protein-Coupled; Receptors, Mating Factor; Receptors, Peptide; Saccharomyces cerevisiae Proteins; Serine; Signal Transduction; Threonine; Transcription Factors; Tyrosine | 2005 |
Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct.
Topics: Amine Oxidase (Copper-Containing); Asparagine; Aspartic Acid; Azo Compounds; Binding Sites; Cations, Divalent; Chelating Agents; Cobalt; Copper; Crystallography, X-Ray; Enzyme Inhibitors; Enzyme Stability; Escherichia coli Proteins; Glutamic Acid; Hydrogen-Ion Concentration; Mutagenesis, Site-Directed; Phenylalanine; Pyridones; Resorcinols; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tyrosine | 2005 |
Cyclic enkephalin analogs containing various para-substituted phenylalanine derivatives in place of Tyr1 are potent opioid agonists.
Topics: Animals; Enkephalins; Guinea Pigs; Inhibitory Concentration 50; Mice; Narcotics; Phenylalanine; Receptors, Opioid; Tyrosine | 2005 |
High protein diet mimics hypertyrosinemia in newborn infants.
Topics: Diagnosis, Differential; Diet Therapy; Dietary Proteins; Female; Humans; Infant Food; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Treatment Outcome; Tyrosine; Tyrosinemias | 2005 |
Photolabeling study of the ligand binding domain of natriuretic peptide receptor A: development of a model.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Cell Line; Guanylate Cyclase; Histidine; Humans; Leucine; Ligands; Methionine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Natriuretic Peptide, Brain; Peptide Fragments; Phenylalanine; Photoaffinity Labels; Protein Structure, Tertiary; Protein Subunits; Receptors, Atrial Natriuretic Factor; Sequence Homology, Amino Acid; Thermodynamics; Tyrosine; Valine | 2005 |
Characteristic of aromatic amino acid substitution at alpha 96 of hemoglobin.
Topics: Amino Acid Substitution; Hemoglobins; Humans; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Mutation; Oxygen; Phenylalanine; Protein Subunits; Recombinant Proteins; Tryptophan; Tyrosine; Valine | 2005 |
Base selectivity is impaired by mutants that perturb hydrogen bonding networks in the RB69 DNA polymerase active site.
Topics: Alanine; Amino Acid Substitution; Base Pair Mismatch; Binding Sites; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA-Directed DNA Polymerase; Enterobacter; Hydrogen Bonding; Kinetics; Nucleotides; Phenylalanine; Substrate Specificity; Thymine Nucleotides; Toluene; Tyrosine; Viral Proteins | 2005 |
A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
Topics: Animals; Arginine; Ascaris suum; Aspartic Acid; Catalytic Domain; Deuterium Exchange Measurement; Hydrogen-Ion Concentration; Kinetics; Lysine; Malate Dehydrogenase; Models, Chemical; NAD; Phenylalanine; Spectrophotometry; Substrate Specificity; Tyrosine | 2005 |
Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates.
Topics: Archaeal Proteins; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Conserved Sequence; Crystallography, X-Ray; Fructose-Bisphosphate Aldolase; Glutamic Acid; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Schiff Bases; Structure-Activity Relationship; Substrate Specificity; Thermoproteus; Tyrosine | 2005 |
Structural details of the thermophilic filamentous bacteriophage PH75 determined by polarized Raman microspectroscopy.
Topics: Amides; Amino Acid Sequence; Capsid; DNA, Single-Stranded; DNA, Viral; Inovirus; Models, Molecular; Molecular Sequence Data; Phenylalanine; Protein Structure, Secondary; Protein Subunits; Spectrum Analysis, Raman; Thermus thermophilus; Tryptophan; Tyrosine | 2005 |
A stable FeIII-FeIV replacement of tyrosyl radical in a class I ribonucleotide reductase.
Topics: Chlamydia trachomatis; Electron Spin Resonance Spectroscopy; Iron; Oxidation-Reduction; Phenylalanine; Protein Binding; Ribonucleotide Reductases; Tyrosine | 2005 |
Homology modeling and PAPS ligand (cofactor) binding study of bovine phenol sulfotransferase.
Topics: Amino Acid Sequence; Animals; Arylsulfotransferase; Binding Sites; Cattle; Coenzyme A; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Sequence Data; Phenylalanine; Phosphoadenosine Phosphosulfate; Protein Binding; Protein Conformation; Tyrosine | 2005 |
Novel missense mutations in two patients with factor XI deficiency (Val271Leu and Tyr351Ser) and one patient with combined factor XI and factor IX deficiency (Phe349Val).
Topics: Child; Codon; DNA Primers; Exons; Factor IX; Factor XI; Factor XI Deficiency; Female; Genotype; Hemophilia B; Hemorrhage; Humans; Introns; Leucine; Male; Mutation; Mutation, Missense; Phenotype; Phenylalanine; Polymerase Chain Reaction; Serine; Tyrosine; Valine | 2005 |
Alternative binding modes of proline-rich peptides binding to the GYF domain.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Carrier Proteins; CD2 Antigens; Computer Simulation; Glycine; Humans; Ligands; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Solvents; Thermodynamics; Tyrosine | 2005 |
Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site.
Topics: Asparagine; Bacterial Proteins; Binding Sites; Bromides; Catalytic Domain; Chlorides; Hydrolases; Kinetics; Ligands; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Rhizobium; Spectrometry, Fluorescence; Stereoisomerism; Tryptophan; Tyrosine | 2005 |
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.
Topics: Amino Acids; Animals; Antioxidants; Carbon; Cerebral Cortex; Chromatography, High Pressure Liquid; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Glucose; Guanidines; Hydroxyl Radical; Hyperglycemia; Lipid Metabolism; Lipid Peroxidation; Lipoproteins, LDL; Male; Mass Spectrometry; Oxidative Stress; Oxygen; Phenylalanine; Rats; Rats, Sprague-Dawley; Retina; Ribonuclease, Pancreatic; Temperature; Tyrosine | 2005 |
Identification of an acquired JAK2 mutation in polycythemia vera.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cytokines; DNA Mutational Analysis; DNA, Complementary; Erythropoietin; HeLa Cells; Heterozygote; Humans; Immunoblotting; Janus Kinase 2; Molecular Sequence Data; Mutation; Phenylalanine; Point Mutation; Polycythemia Vera; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Signal Transduction; Transfection; Tyrosine; Valine | 2005 |
Mechanistic studies of mouse polyamine oxidase with N1,N12-bisethylspermine as a substrate.
Topics: Animals; Catalysis; Flavoproteins; Hydrogen-Ion Concentration; Kinetics; Mice; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Phenylalanine; Polyamine Oxidase; Spermine; Substrate Specificity; Tyrosine | 2005 |
Characterisation of tyrosine-phosphorylation-defective calmodulin mutants.
Topics: Amino Acid Substitution; Animals; Calmodulin; Escherichia coli; Gene Expression; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphorylation; Rats; Tyrosine | 2005 |
Combination cancer chemotherapy with one compound: pluripotent bradykinin antagonists.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bradykinin; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Guinea Pigs; Humans; Ileum; Matrix Metalloproteinase Inhibitors; Mice; Mice, Nude; Oligopeptides; Phenylalanine; Rabbits; Rats; Structure-Activity Relationship; Tyrosine | 2005 |
Substrate-induced tryptophan fluorescence changes in EmrE, the smallest ion-coupled multidrug transporter.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antiporters; Biological Transport; Drug Resistance, Multiple, Bacterial; Escherichia coli Proteins; Membrane Proteins; Molecular Sequence Data; Mutagenesis, Site-Directed; Onium Compounds; Organophosphorus Compounds; Phenotype; Phenylalanine; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2005 |
Influence of the separation of the charged groups and aromatic ring on interaction of tyrosine and phenylalanine analogues and derivatives with beta-cyclodextrin.
Topics: beta-Cyclodextrins; Calorimetry; Hydrogen-Ion Concentration; Molecular Structure; Phenylalanine; Spectrometry, Fluorescence; Static Electricity; Thermodynamics; Time Factors; Tyrosine | 2005 |
Probing the hydroxyl radical-mediated reactivity of peroxynitrite by a spin-labeling fluorophore.
Topics: Carbon Dioxide; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Fluorescent Dyes; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxyl Radical; Indicators and Reagents; Peroxynitrous Acid; Phenylalanine; Reproducibility of Results; Solvents; Spectrometry, Fluorescence; Spin Labels; Tyrosine | 2005 |
Theoretical and experimental investigations on the reactions of positively charged phenyl radicals with aromatic amino acids.
Topics: Amino Acids, Aromatic; Benzene Derivatives; Cysteine; Free Radicals; Models, Molecular; Phenylalanine; Pyridinium Compounds; Thermodynamics; Tryptophan; Tyrosine | 2005 |
Kinetic analysis of the role of the tyrosine 13, phenylalanine 56 and glutamine 54 network in the U1A/U1 hairpin II interaction.
Topics: Amino Acid Sequence; Amino Acid Substitution; DNA Mutational Analysis; Glutamic Acid; Glutamine; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Phenylalanine; Protein Binding; Ribonucleoprotein, U1 Small Nuclear; RNA-Binding Proteins; RNA, Small Nuclear; Tyrosine | 2005 |
Characterization of free aromatic amino acids and estimation of exposition rate of phenylalanine in casein hydrolysates by second derivative spectrophotometry.
Topics: Caseins; Hydrogen-Ion Concentration; Papain; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 2004 |
Compact detector for proteins based on two-photon excitation of native fluorescence.
Topics: Animals; Cattle; Equipment Design; Equipment Failure Analysis; Fluorescence; Lab-On-A-Chip Devices; Lasers; Microchip Analytical Procedures; Optics and Photonics; Phenylalanine; Photons; Sensitivity and Specificity; Serum Albumin, Bovine; Time Factors; Tryptophan; Tyrosine | 2005 |
Synthesis and sequence optimization of GFP mutants containing aromatic non-natural amino acids at the Tyr66 position.
Topics: Cell-Free System; Codon; Escherichia coli; Gene Library; Green Fluorescent Proteins; Mutagenesis; Mutation; Phenylalanine; Protein Engineering; RNA, Transfer; Tyrosine | 2005 |
Whole-body and hindlimb protein breakdown are differentially altered by feeding in neonatal piglets.
Topics: Animals; Animals, Newborn; Blood Glucose; Eating; Hindlimb; Hydroxylation; Insulin; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Swine; Tyrosine | 2005 |
Arc repressor-operator DNA interactions and contribution of Phe10 to binding specificity.
Topics: Amino Acid Substitution; Circular Dichroism; Crystallography, X-Ray; Deoxyribonucleosides; Deoxyribose; DNA-Binding Proteins; DNA, Viral; Histidine; Hydrophobic and Hydrophilic Interactions; Nucleic Acid Conformation; Operator Regions, Genetic; Phenylalanine; Purines; Pyrimidines; Repressor Proteins; Salmonella; Spectrometry, Fluorescence; Spectrum Analysis, Raman; Thermodynamics; Tryptophan; Tyrosine; Viral Proteins; Viral Regulatory and Accessory Proteins | 2005 |
Insights into the role of the aromatic residue in galactose-binding sites: MP2/6-311G++** study on galactose- and glucose-aromatic residue analogue complexes.
Topics: Amino Acid Sequence; Binding Sites; Butylated Hydroxytoluene; Carbohydrate Conformation; Galactose; Galectins; Glucose; Hydrogen Bonding; Models, Chemical; Molecular Sequence Data; Oligosaccharides; Phenylalanine; Skatole; Thermodynamics; Tryptophan; Tyrosine | 2005 |
Infrared fingerprint spectroscopy and theoretical studies of potassium ion tagged amino acids and peptides in the gas phase.
Topics: Cations, Monovalent; Gases; Models, Molecular; Oligopeptides; Phenylalanine; Potassium; Spectrophotometry, Infrared; Tyrosine | 2005 |
Short communication: Amino acids antagonistic to the amino acids inhibitory for growth rate of mixed ruminal bacteria.
Topics: Amino Acids; Animals; Bacteria; Cattle; Diet; Feedback, Physiological; Female; Fermentation; Glutamic Acid; Isoleucine; Leucine; Nitrogen; Phenylalanine; Rumen; Threonine; Tryptophan; Tyrosine; Valine | 2005 |
PPAR-gamma ligands and amino acid deprivation promote apoptosis of melanoma, prostate, and breast cancer cells.
Topics: Amino Acids; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Immunologic Factors; Ligands; Male; Melanoma; Methionine; Phenylalanine; PPAR gamma; Prostaglandin D2; Prostatic Neoplasms; Thiazolidinediones; Tyrosine | 2006 |
Amino acid substitutions in the pore of the Ca(V)1.2 calcium channel reduce barium currents without affecting calcium currents.
Topics: Amino Acid Sequence; Barium; Biological Transport; Calcium; Calcium Channels; Calcium Channels, L-Type; Cations; Cations, Divalent; Cell Line; DNA, Complementary; Dose-Response Relationship, Drug; Glutamic Acid; Glycine; Humans; Hydrogen-Ion Concentration; Inhibitory Concentration 50; Ion Channel Gating; Ions; Kinetics; Lysine; Membrane Potentials; Molecular Sequence Data; Mutation; Patch-Clamp Techniques; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Tyrosine | 2005 |
A newly identified HLA-C allele: Cw*1210, and confirmation of HLA-Cw*080102.
Topics: Alleles; Base Sequence; Codon; Exons; HLA-C Antigens; Humans; Molecular Sequence Data; Phenylalanine; Sequence Analysis, DNA; Taiwan; Tyrosine | 2005 |
Local anesthetic interaction with human ether-a-go-go-related gene (HERG) channels: role of aromatic amino acids Y652 and F656.
Topics: Anesthetics, Local; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Membrane Potentials; Mutation; Phenylalanine; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Tyrosine | 2005 |
Direct tyrosine oxidation using the MLCT excited states of rhenium polypyridyl complexes.
Topics: Amides; Electrochemistry; Electron Transport; Ethylenes; Free Radicals; Hydrogen-Ion Concentration; Luminescent Measurements; Organometallic Compounds; Oxidation-Reduction; Phenylalanine; Phosphines; Photochemistry; Protons; Pyridines; Rhenium; Spectrophotometry; Tyrosine | 2005 |
Raman spectroscopic study on structure of human immunodeficiency virus (HIV) and hypericin-induced photosensitive damage of HIV.
Topics: Anthracenes; HIV; HIV Seropositivity; HIV-1; HIV-2; Humans; Hydrogen Bonding; Lipid Bilayers; Perylene; Phenylalanine; Protein Structure, Secondary; Radiation-Sensitizing Agents; RNA, Viral; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Viral Proteins | 2005 |
Evolution of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase-encoding genes in the yeast Saccharomyces cerevisiae.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Aldehyde-Lyases; Amino Acids; Escherichia coli; Evolution, Molecular; Feedback, Physiological; Genetic Engineering; Isoenzymes; Mutation; Phenylalanine; Promoter Regions, Genetic; Saccharomyces cerevisiae; Tryptophan; Tyrosine | 2005 |
Mutation of the adenylylated tyrosine of glutamine synthetase alters its catalytic properties.
Topics: Adenine; Adenosine Diphosphate; Adenosine Monophosphate; Alanine; Catalysis; Cations, Divalent; Enzyme Activation; Escherichia coli Proteins; Esterification; Feedback, Physiological; gamma-Glutamyltransferase; Glutamate-Ammonia Ligase; Glutamine; Hydrogen-Ion Concentration; Hydroxides; Magnesium; Manganese; Mutagenesis, Site-Directed; Phenylalanine; Serine; Tyrosine | 2005 |
The type 1 cysteinyl leukotriene receptor triggers calcium influx and chemotaxis in mouse alpha beta- and gamma delta effector T cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium; Calcium Signaling; Chemotaxis, Leukocyte; Intracellular Fluid; Leukotriene D4; Ligands; Lymphocyte Activation; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; Phenylalanine; Phosphoproteins; Receptors, Antigen, T-Cell, alpha-beta; Receptors, Antigen, T-Cell, gamma-delta; Receptors, Leukotriene; T-Lymphocyte Subsets; T-Lymphocytes, Regulatory; Tyrosine | 2005 |
An intact phosphocholine binding site is necessary for transgenic rabbit C-reactive protein to protect mice against challenge with platelet-activating factor.
Topics: Animals; Binding Sites; C-Reactive Protein; Complement Activation; Dietary Carbohydrates; Dietary Proteins; Glutamic Acid; Lysine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylalanine; Phosphorylcholine; Platelet Activating Factor; Protein Binding; Rabbits; Survival Analysis; Tyrosine | 2005 |
Binding residues and catalytic domain of soluble Saccharomyces cerevisiae processing alpha-glucosidase I.
Topics: 1-Deoxynojirimycin; alpha-Glucosidases; Amino Acid Sequence; Binding Sites; Bromosuccinimide; Catalysis; Catalytic Domain; Diethyl Pyrocarbonate; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Inhibitors; Gene Expression Regulation, Fungal; Glycoside Hydrolases; Glycosylation; Glyoxal; Histidine; Hydrolysis; Lysine; Molecular Sequence Data; Peptides; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Saccharomyces cerevisiae; Temperature; Tetranitromethane; Time Factors; Trisaccharides; Trypsin; Tryptophan; Tyrosine | 2005 |
Development of microwave-assisted derivatization followed by gas chromatography/mass spectrometry for fast determination of amino acids in neonatal blood samples.
Topics: Amino Acids; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Microwaves; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Time Factors; Tyrosine | 2005 |
Tandem mass spectrometry of deprotonated iodothyronines.
Topics: Deuterium Exchange Measurement; Hydrogen-Ion Concentration; Molecular Structure; Phenylalanine; Protons; Spectrometry, Mass, Electrospray Ionization; Triiodothyronine; Tyrosine | 2005 |
Single-spanning membrane protein insertion in membrane mimetic systems: role and localization of aromatic residues.
Topics: Amino Acids, Aromatic; Anisotropy; Biomimetics; Glucosides; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Magnetic Resonance Spectroscopy; Membrane Proteins; Micelles; Peptide Fragments; Phenylalanine; Phosphatidylcholines; Phosphatidylserines; Proton-Translocating ATPases; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Yeasts | 2005 |
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamic Acid; Humans; Hypersensitivity; Indomethacin; Inflammation; Kinetics; Ligands; Mice; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Tyrosine | 2005 |
Role of the C-terminus of the high-conductance calcium-activated potassium channel in channel structure and function.
Topics: Aspartic Acid; Cell Line; Cell Membrane; Humans; Iodine Radioisotopes; Large-Conductance Calcium-Activated Potassium Channels; Monoiodotyrosine; Peptide Fragments; Peptides; Phenylalanine; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Protein Transport; Scorpion Venoms; Transfection; Tyrosine | 2005 |
Removal of tightly bound ADP induces distinct structural changes of the two tryptophan-containing regions of the ncd motor domain.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Binding Sites; Circular Dichroism; Drosophila Proteins; Kinesins; Models, Molecular; Mutation; Phenylalanine; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tryptophan; Tubulin; Tyrosine | 2005 |
A novel mechanism of modulation of hyperpolarization-activated cyclic nucleotide-gated channels by Src kinase.
Topics: Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Cyclic Nucleotide-Gated Cation Channels; Electrophysiology; Humans; Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels; Ion Channel Gating; Ion Channels; Kidney; Kinetics; Mass Spectrometry; Membrane Potentials; Mice; Muscle Proteins; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Plasmids; Potassium Channels; src Homology Domains; src-Family Kinases; Two-Hybrid System Techniques; Tyrosine; Yeasts | 2005 |
Phenylalanine 4-monooxygenase and the S-oxidation of S-carboxymethyl-L-cysteine in HepG2 cells.
Topics: 2,2'-Dipyridyl; Amino Acids, Aromatic; Carbocysteine; Cell Line; Coenzymes; Cysteic Acid; Cytosol; Deferoxamine; Enzyme Inhibitors; Humans; Iron Chelating Agents; Methionine; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Time Factors; Tyrosine | 2005 |
Helix switching of a key active-site residue in the cytochrome cbb3 oxidases.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Electron Transport Complex IV; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sequence Alignment; Tyrosine; Vibrio cholerae | 2005 |
Roles of tyrosine residues 845, 892 and 922 in constitutive activation of murine FLT3 kinase domain mutant.
Topics: Amino Acid Substitution; Animals; Cell Division; Cell Line; Cell Survival; Enzyme Activation; fms-Like Tyrosine Kinase 3; Kidney; Mice; Phenylalanine; Polymorphism, Single Nucleotide; Recombinant Proteins; Transfection; Tyrosine | 2005 |
Four novel connexin 32 mutations in X-linked Charcot-Marie-Tooth disease with phenotypic variability.
Topics: Adolescent; Adult; Aged; Aspartic Acid; Charcot-Marie-Tooth Disease; Chromosomes, Human, X; Codon, Terminator; Connexins; DNA Mutational Analysis; Family Health; Female; Gap Junction beta-1 Protein; Humans; Leucine; Male; Middle Aged; Mutation; Phenotype; Phenylalanine; Proline; Serine; Tyrosine; Valine | 2006 |
A novel HLA allele, DRB1*1609, identified in the Chinese Han population*.
Topics: Alleles; Base Sequence; China; Exons; Family Health; Female; Histocompatibility Testing; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Male; Molecular Sequence Data; Pedigree; Phenotype; Phenylalanine; Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid; Tyrosine | 2005 |
[Determination of phenylalanine and tyrosine in serum by high-performance liquid chromatography with fluorescent detection].
Topics: Adolescent; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Fluorescence; Humans; Infant; Male; Phenylalanine; Tyrosine | 2004 |
NMR assignment methods for the aromatic ring resonances of phenylalanine and tyrosine residues in proteins.
Topics: Carbon Isotopes; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Proteins; Protons; Reference Standards; Tyrosine | 2005 |
Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Binding Sites; Cytosol; DNA-Directed RNA Polymerases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Evolution, Molecular; Kinetics; Mitochondria; Models, Biological; Models, Genetic; Molecular Sequence Data; Nucleic Acid Conformation; Phenylalanine; Phenylalanine-tRNA Ligase; Phosphates; Phylogeny; Plasmids; Point Mutation; Protein Biosynthesis; Ribosomes; RNA Editing; RNA, Transfer; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Substrate Specificity; Time Factors; Transcription, Genetic; Tyrosine; Viral Proteins | 2005 |
Role of aromatic localization in the gating process of a potassium channel.
Topics: Biophysics; Cell Membrane; Computer Simulation; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Ion Channel Gating; Lipid Bilayers; Lipids; Models, Molecular; Molecular Conformation; Phenylalanine; Potassium Channels; Time Factors; Tyrosine | 2006 |
Urinary ortho-tyrosine excretion in diabetes mellitus and renal failure: evidence for hydroxyl radical production.
Topics: Aged; Cross-Sectional Studies; Diabetic Nephropathies; Female; Humans; Hydroxyl Radical; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Phenylalanine; Tyrosine | 2005 |
Activated EGF receptor may balance ERK-inhibitory network signalling pathways.
Topics: Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Cyclic AMP; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Mutation; Phenylalanine; Phosphorylation; Receptor, Bradykinin B2; Receptors, Adrenergic, beta-2; Signal Transduction; src-Family Kinases; Tyrosine | 2006 |
Lineage-specific variations of congruent evolution among DNA sequences from three genomes, and relaxed selective constraints on rbcL in Cryptomonas (Cryptophyceae).
Topics: Asparagine; Aspartic Acid; Bayes Theorem; Codon; Cryptophyta; Cysteine; DNA; DNA, Ribosomal; Evolution, Molecular; Genome; Histidine; Likelihood Functions; Phenylalanine; Photosynthesis; Phylogeny; Plastids; Polymerase Chain Reaction; Ribulose-Bisphosphate Carboxylase; Sequence Analysis, DNA; Tyrosine | 2005 |
Purification and characterization of spiralin, the main protein of the Spiroplasma citri membrane.
Topics: Alanine; Bacterial Outer Membrane Proteins; Biochemistry; Buffers; Cell Membrane; Detergents; Electrophoresis; Electrophoresis, Agar Gel; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Glycine; Histidine; Immunoelectrophoresis; Intracellular Membranes; Leucine; Methionine; Molecular Weight; Phenylalanine; Sepharose; Spiroplasma citri; Subcellular Fractions; Threonine; Tryptophan; Tyrosine; Valine | 1977 |
Thermodynamic functions and intra-particle mass transfer kinetics of structural analogues of a template on molecularly imprinted polymers in liquid chromatography.
Topics: Adsorption; Algorithms; Chromatography, Liquid; Fluorenes; Glycine; Kinetics; Models, Chemical; Particle Size; Phenylalanine; Polymers; Serine; Stereoisomerism; Temperature; Thermodynamics; Tryptophan; Tyrosine | 2005 |
Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase.
Topics: Aged; Cataract; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dihydroxyphenylalanine; Eye Proteins; Humans; Hydroxyl Radical; Lens, Crystalline; Middle Aged; Phenylalanine; Solubility; Tyrosine; Water | 2005 |
An amino acid contributing to pockets A, B, and D of the peptide-binding groove is altered in A*0315.
Topics: Adult; Alleles; Binding Sites; Female; Genetic Variation; HLA-A Antigens; Humans; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Protein Binding; Tyrosine; White People | 2005 |
Recruitment of the tyrosine phosphatase Src homology 2 domain tyrosine phosphatase-2 to the p85 subunit of phosphatidylinositol-3 (PI-3) kinase is required for insulin-like growth factor-I-dependent PI-3 kinase activation in smooth muscle cells.
Topics: Animals; Aorta; Cell Movement; Cells, Cultured; Enzyme Activation; Fibroblasts; Humans; Immunoblotting; Immunoprecipitation; Insulin-Like Growth Factor I; Models, Statistical; Muscle, Smooth; Mutation; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Swine; Tyrosine | 2006 |
Cutaneous metabolism of a dipeptide influences the iontophoretic flux of a concomitant uncharged permeant.
Topics: Dipeptides; Electric Impedance; Epidermis; Female; Glucose; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Iontophoresis; Osmosis; Permeability; Phenylalanine; Skin; Skin Absorption; Temperature; Time Factors; Tyrosine | 2006 |
Point mutation at single tyrosine residue of novel oncogene NOK abrogates tumorigenesis in nude mice.
Topics: Amino Acid Sequence; Animals; Apoptosis; Binding Sites; Caspase 3; Caspases; Cell Growth Processes; Cell Transformation, Neoplastic; Conserved Sequence; Enzyme Activation; Mice; Mice, Nude; Molecular Sequence Data; Oncogene Proteins; Phenylalanine; Phosphorylation; Point Mutation; Receptor Protein-Tyrosine Kinases; Sequence Alignment; Transfection; Tyrosine | 2005 |
[Regulation of 3-desoxy-D-arabino-heptulosonate-7-phosphate synthetase in the bacteria Pseudomonas aurantiaca B-162].
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; Mutation; Phenylalanine; Pseudomonas; Tyrosine | 2005 |
Structural basis for discrimination of L-phenylalanine from L-tyrosine by phenylalanyl-tRNA synthetase.
Topics: Crystallography; Mutagenesis, Site-Directed; Phenylalanine; Phenylalanine-tRNA Ligase; Protein Conformation; Substrate Specificity; Thermus thermophilus; Tyrosine | 2005 |
Misincorporation of free m-tyrosine into cellular proteins: a potential cytotoxic mechanism for oxidized amino acids.
Topics: Animals; Carbon Radioisotopes; Cell Death; Cells, Cultured; CHO Cells; Cricetinae; Cycloheximide; Oxidation-Reduction; Phenylalanine; Protein Biosynthesis; Proteins; Spectrum Analysis; Transcription, Genetic; Tyrosine | 2006 |
Cellular ITAM-containing proteins are oncoproteins in nonhematopoietic cells.
Topics: Amino Acid Motifs; Amino Acid Substitution; Animals; Cell Transformation, Neoplastic; Colony-Forming Units Assay; Epithelial Cells; Female; Fibroblasts; Flow Cytometry; Fluorescent Antibody Technique; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Male; Mammary Glands, Animal; Mice; NIH 3T3 Cells; Oncogene Proteins; Phenylalanine; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; src-Family Kinases; Syk Kinase; Tyrosine | 2006 |
Comparison of metal-amino acid interaction in Phe-Ag and Tyr-Ag complexes by spectroscopic measurements.
Topics: Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Phenylalanine; Silver; Spectrum Analysis, Raman; Tyrosine | 2006 |
Role of Tyr348 in Tyr385 radical dynamics and cyclooxygenase inhibitor interactions in prostaglandin H synthase-2.
Topics: Amino Acid Substitution; Aspirin; Binding Sites; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrogen Bonding; Isoenzymes; Mutation; Peroxidases; Phenylalanine; Protein Conformation; Substrate Specificity; Sulfonamides; Thermodynamics; Tyrosine | 2006 |
G-protein-coupled receptor 1, G-protein Galpha-subunit 1, and prephenate dehydratase 1 are required for blue light-induced production of phenylalanine in etiolated Arabidopsis.
Topics: Amino Acid Sequence; Anthocyanins; Arabidopsis; Arabidopsis Proteins; Cytosol; Gene Expression Regulation, Plant; GTP-Binding Protein alpha Subunits; Light; Light-Harvesting Protein Complexes; Models, Genetic; Molecular Sequence Data; Mutation; Phenylalanine; Prephenate Dehydratase; Protein Interaction Mapping; Receptors, G-Protein-Coupled; Signal Transduction; Tyrosine | 2006 |
Crystal structure at 1.45-A resolution of the major allergen endo-beta-1,3-glucanase of banana as a molecular basis for the latex-fruit syndrome.
Topics: Allergens; Amino Acid Sequence; Binding Sites; Catalysis; Catalytic Domain; Cross Reactions; Crystallography, X-Ray; Epitopes; Epitopes, B-Lymphocyte; Food Hypersensitivity; Fruit; Glucan Endo-1,3-beta-D-Glucosidase; Glucose; Glutamic Acid; Immunoglobulin E; Latex; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Musa; Phenylalanine; Polysaccharides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Proteins; Proteomics; Substrate Specificity; Syndrome; Time Factors; Triose-Phosphate Isomerase; Tyrosine | 2006 |
Polymorphic amino acids at codons 9 and 37 of HLA-DQB1 alleles may confer susceptibility to cervical cancer among Chinese women.
Topics: Amino Acid Sequence; Amino Acids; Aspartic Acid; Case-Control Studies; China; Codon; DNA, Viral; Female; Gene Frequency; Genetic Predisposition to Disease; HLA-DQ Antigens; HLA-DQ beta-Chains; Human papillomavirus 16; Humans; Isoleucine; Leucine; Papillomavirus Infections; Phenylalanine; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Sequence Analysis, DNA; Tyrosine; Uterine Cervical Neoplasms | 2006 |
The interaction of Phe472 with a fluorescent inhibitor bound to the complex of myosin subfragment-1 with nucleotide.
Topics: Adenosine Triphosphate; Binding Sites; Boronic Acids; Fluorescent Dyes; Heterocyclic Compounds, 4 or More Rings; Models, Molecular; Myosin Subfragments; Nucleotides; Phenylalanine; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Sulfonamides; Tryptophan; Tyrosine | 2006 |
Critical and distinct roles for key RET tyrosine docking sites in renal development.
Topics: Animals; Apoptosis; Gonads; Humans; Kidney; Mice; Mice, Mutant Strains; Morphogenesis; Mutation; Phenylalanine; Phospholipase C gamma; Protein Isoforms; Proto-Oncogene Proteins c-ret; Signal Transduction; Tyrosine; Ureter | 2006 |
Tryptophanase from Proteus vulgaris: the conformational rearrangement in the active site, induced by the mutation of Tyrosine 72 to phenylalanine, and its mechanistic consequences.
Topics: Amino Acid Sequence; Binding Sites; Catalysis; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Proteus vulgaris; Tryptophanase; Tyrosine | 2006 |
Site-directed mutagenesis study of the microenvironment characteristics of Lys213 of Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase.
Topics: Circular Dichroism; Hydrogen-Ion Concentration; Kinetics; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Phosphoenolpyruvate Carboxykinase (ATP); Point Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Spectrometry, Fluorescence; Tyrosine | 2006 |
A residual structure in unfolded intestinal fatty acid binding protein consists of amino acids that are neighbors in the native state.
Topics: Amino Acids; Circular Dichroism; Fatty Acid-Binding Proteins; Fluorescence; Fluorine; Hydrophobic and Hydrophilic Interactions; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Recombinant Proteins; Tryptophan; Tyrosine; Urea | 2006 |
The history of hypertyrosinemia caused by high protein diets.
Topics: Dietary Proteins; Humans; Infant Food; Infant, Newborn; Intellectual Disability; Phenylalanine; Tyrosine; Tyrosinemias | 2006 |
A simple procedure for the photoregulation of chymotrypsin activity.
Topics: Animals; Cattle; Chymotrypsin; Enzyme Activation; Ethanol; Molecular Structure; Nitrobenzenes; Phenylalanine; Photochemistry; Serum Albumin, Bovine; Tyrosine; Ultraviolet Rays | 2006 |
Crystal structure of type-III geranylgeranyl pyrophosphate synthase from Saccharomyces cerevisiae and the mechanism of product chain length determination.
Topics: Amino Acid Motifs; Amino Acid Sequence; Crystallography, X-Ray; Dimerization; Geranylgeranyl-Diphosphate Geranylgeranyltransferase; Histidine; Kinetics; Magnesium; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Tyrosine | 2006 |
Ligand exchange capillary electrophoresis by cyclodextrin derivatives, a powerful tool for enantiomeric separations.
Topics: Amino Acids; Aminopyridines; beta-Cyclodextrins; Cyclodextrins; Electrophoresis, Capillary; Ligands; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine | 2006 |
Responses of whole body protein synthesis, nitrogen retention and glucose kinetics to supplemental starch in goats.
Topics: Animals; Blood Urea Nitrogen; Butyrates; Dietary Supplements; Energy Intake; Energy Metabolism; Fatty Acids; Glucose; Goats; Insulin; Isotopes; Lactic Acid; Male; Nitrogen; Phenylalanine; Propionates; Protein Biosynthesis; Starch; Tyrosine | 2006 |
Assessing the role of aromatic residues in the amyloid aggregation of human muscle acylphosphatase.
Topics: Acid Anhydride Hydrolases; Acylphosphatase; Amino Acid Substitution; Amyloid; Benzothiazoles; Birefringence; Circular Dichroism; Congo Red; Data Interpretation, Statistical; Humans; Hydrophobic and Hydrophilic Interactions; Muscles; Phase Transition; Phenylalanine; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Thiazoles; Trifluoroethanol; Tyrosine | 2006 |
Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydroxyl Radical; Hydroxylation; Male; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Perfusion; Phenylalanine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Tyrosine | 2006 |
The crystal structure of NAD(P)H quinone oxidoreductase 1 in complex with its potent inhibitor dicoumarol.
Topics: Animals; Apoproteins; Benzoquinones; Catalytic Domain; Crystallization; Crystallography, X-Ray; Dicumarol; Enzyme Inhibitors; Humans; Indolequinones; Models, Molecular; NAD(P)H Dehydrogenase (Quinone); Phenylalanine; Protein Binding; Protein Conformation; Rats; Triazines; Tyrosine | 2006 |
Elevated plasma phenylalanine in severe malaria and implications for pathophysiology of neurological complications.
Topics: Child; Child, Preschool; Dystonia; Female; Humans; Infant; Malaria; Malaria, Cerebral; Male; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine | 2006 |
Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal.
Topics: Amino Acids; Blood Flow Velocity; Diabetes Mellitus, Type 1; Glucose; Humans; Hypoglycemic Agents; Insulin; Kidney; Leucine; Palmitic Acid; Phenylalanine; Reference Values; Renal Circulation; Substance Withdrawal Syndrome; Tyrosine | 2006 |
Atypical tetracyclic antidepressant maprotiline is an antagonist at cardiac hERG potassium channels.
Topics: Animals; Antidepressive Agents; Cell Line; Electrophysiology; Ether-A-Go-Go Potassium Channels; Humans; Maprotiline; Molecular Structure; Mutation; Oocytes; Patch-Clamp Techniques; Phenylalanine; Polycyclic Compounds; Potassium Channel Blockers; Tyrosine; Xenopus laevis | 2006 |
Tyr-48, a conserved residue in ribotoxins, is involved in the RNA-degrading activity of alpha-sarcin.
Topics: Circular Dichroism; Endoribonucleases; Fungal Proteins; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Mutant Proteins; Phenylalanine; Phosphatidylglycerols; Protein Denaturation; Protein Structure, Tertiary; RNA, Fungal; Spectrometry, Fluorescence; Structure-Activity Relationship; Tyrosine | 2006 |
Significance of the extra C-terminal tail of CaLP, a novel calmodulin-like protein involved in oyster calcium metabolism.
Topics: Amino Acid Sequence; Animals; Calcium; Calmodulin; Carrier Proteins; Chromatography, Affinity; Circular Dichroism; Electrophoretic Mobility Shift Assay; Magnesium; Molecular Sequence Data; Mutation; Ostreidae; Phenylalanine; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence; Tyrosine | 2006 |
Structures of apo- and holo-tyrosine phenol-lyase reveal a catalytically critical closed conformation and suggest a mechanism for activation by K+ ions.
Topics: Apoenzymes; Arginine; Binding Sites; Catalysis; Citrobacter freundii; Crystallography, X-Ray; Enzyme Activation; Glutamine; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Phenylalanine; Potassium; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Pyridoxal Phosphate; Substrate Specificity; Tyrosine; Tyrosine Phenol-Lyase | 2006 |
Physical and functional interaction of Fyn tyrosine kinase with a brain-enriched Rho GTPase-activating protein TCGAP.
Topics: Amino Acid Substitution; Animals; Brain; Cell Line; Enzyme Activation; Gene Expression Regulation, Developmental; Growth Inhibitors; GTPase-Activating Proteins; Humans; Nerve Growth Factor; Neurites; PC12 Cells; Phenylalanine; Phosphorylation; Proto-Oncogene Proteins c-fyn; Rats; rho GTP-Binding Proteins; Sorting Nexins; Subcellular Fractions; Tyrosine | 2006 |
Aspartic acid 214 in Citrobacter freundii tyrosine phenol-lyase ensures sufficient C--H-acidity of the external aldimine intermediate and proper orientation of the cofactor at the active site.
Topics: Alanine; Apoenzymes; Asparagine; Aspartic Acid; Binding Sites; Catalysis; Circular Dichroism; Citrobacter freundii; Coenzymes; Deuterium Oxide; Homoserine; Kinetics; Molecular Structure; Mutation; Phenylalanine; Recombinant Fusion Proteins; Spectrophotometry; Tyrosine; Tyrosine Phenol-Lyase | 2006 |
Role of the activation loop tyrosines in regulation of the insulin-like growth factor I receptor-tyrosine kinase.
Topics: Catalytic Domain; Enzyme Activation; Enzyme Stability; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Conformation; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Substrate Specificity; Tyrosine | 2006 |
Detection of new amino acid markers of liver trauma by proton nuclear magnetic resonance spectroscopy.
Topics: Amino Acids; Bilirubin; Biomarkers; Case-Control Studies; Humans; Liver; Magnetic Resonance Spectroscopy; Phenylalanine; Reference Values; Serum Albumin; Tyrosine | 2006 |
Cationic peptides containing tyrosine protect against radiation-induced oxidative DNA damage.
Topics: Antimicrobial Cationic Peptides; Binding Sites; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Dose-Response Relationship, Drug; Gamma Rays; Ligands; Phenylalanine; Radiation-Protective Agents; Reactive Oxygen Species; Thiocyanates; Time Factors; Tryptophan; Tyrosine | 2006 |
Synthesis and characterization of nonconventional surfactants of aromatic amino acid-glycerol ethers: effect of the amino acid moiety on the orientation and surface properties of these soap-type amphiphiles.
Topics: Glyceryl Ethers; Histidine; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylalanine; Surface Properties; Surface Tension; Surface-Active Agents; Tryptophan; Tyrosine | 2006 |
Proximal cavity, distal histidine, and substrate hydrogen-bonding mutations modulate the activity of Amphitrite ornata dehaloperoxidase.
Topics: Animals; Binding Sites; Hemoglobins; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Peroxidases; Phenylalanine; Polychaeta; Substrate Specificity; Tyrosine; Valine | 2006 |
Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.
Topics: Adult; Aged; Aged, 80 and over; Alanine; Cysteine; Female; Glutamic Acid; Glycine; Humans; Leucine; Male; Middle Aged; Multivariate Analysis; Mutation; Phenylalanine; Polymerase Chain Reaction; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Prospective Studies; Receptor, Fibroblast Growth Factor, Type 3; Sequence Analysis, DNA; Serine; Tyrosine; Urinary Bladder Neoplasms | 2006 |
Substrate specificity of the adenylation enzyme SgcC1 involved in the biosynthesis of the enediyne antitumor antibiotic C-1027.
Topics: Adenine Nucleotides; Aminoglycosides; Antibiotics, Antineoplastic; Bacterial Proteins; Enediynes; Multigene Family; Nucleotidyltransferases; Peptide Synthases; Phenylalanine; Point Mutation; Streptomyces; Substrate Specificity; Tyrosine | 2006 |
The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Autoimmune Diseases; B-Lymphocytes; Clone Cells; Lymphocyte Activation; Lymphoproliferative Disorders; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Phenylalanine; Phosphoproteins; Th2 Cells; Tyrosine | 2006 |
Fungal metabolic model for tyrosinemia type 3: molecular characterization of a gene encoding a 4-hydroxy-phenyl pyruvate dioxygenase from Aspergillus nidulans.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Aspergillus nidulans; Gene Deletion; Humans; Models, Biological; Phenylalanine; Phenylpyruvic Acids; Tyrosine; Tyrosinemias | 2006 |
An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Diastole; Echocardiography; ErbB Receptors; Fibrosis; Genes, Dominant; Heart; Mice; Mice, Transgenic; Mutation; Myocardium; Phenylalanine; Receptor, Angiotensin, Type 1; Transcriptional Activation; Tyrosine; Ventricular Function, Left | 2006 |
Expedient synthesis of threo-beta-hydroxy-alpha-amino acid derivatives: phenylalanine, tyrosine, histidine, and tryptophan.
Topics: Amino Acids; Catalysis; Cesium; Chemistry, Organic; Histidine; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine | 2006 |
Inhibition of HERG channels by the local anaesthetic articaine.
Topics: Anesthetics, Local; Animals; Carticaine; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electrophysiology; Ether-A-Go-Go Potassium Channels; Humans; Mutation; Patch-Clamp Techniques; Phenylalanine; Potassium Channel Blockers; Transfection; Tyrosine | 2007 |
Abl tyrosine kinase regulates endocytosis of the epidermal growth factor receptor.
Topics: Amino Acid Substitution; Animals; Cell Line; Chlorocebus aethiops; COS Cells; Culture Media, Serum-Free; Endocytosis; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Fluorescent Dyes; Humans; Ligands; Models, Biological; Phenylalanine; Phosphorylation; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-cbl; Rhodamines; Time Factors; Tyrosine | 2006 |
Structure of the Y94F mutant of Escherichia coli thymidylate synthase.
Topics: Amino Acid Substitution; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Hydroxyl Radical; Phenylalanine; Thymidylate Synthase; Tyrosine; Water | 2006 |
Codon usage bias and tRNA over-expression in Buchnera aphidicola after aromatic amino acid nutritional stress on its host Acyrthosiphon pisum.
Topics: Animals; Anticodon; Aphids; Buchnera; Codon; Cytosine; Diet; Gene Expression Regulation, Bacterial; Guanine; Oligonucleotide Array Sequence Analysis; Phenylalanine; RNA, Transfer; Tyrosine | 2006 |
Aliphatic C-H/pi interactions: Methane-benzene, methane-phenol, and methane-indole complexes.
Topics: Benzene; Indoles; Methane; Molecular Structure; Phenol; Phenylalanine; Thermodynamics; Tryptophan; Tyrosine | 2006 |
Enantioseparation by ligand-exchange using particle-loaded monoliths: capillary-LC versus capillary electrochromatography.
Topics: Acrylamides; Capillary Electrochromatography; Chromatography, Liquid; Ligands; Mandelic Acids; Microscopy, Electron, Scanning; Phenylalanine; Polymers; Stereoisomerism; Tryptophan; Tyrosine | 2007 |
Insights into the reaction mechanism of soluble epoxide hydrolase from theoretical active site mutants.
Topics: Alkylation; Aspartic Acid; Binding Sites; Catalysis; Epoxide Hydrolases; Humans; Models, Chemical; Models, Molecular; Molecular Structure; Mutation; Phenylalanine; Tyrosine | 2006 |
Effect of L-serine on the biosynthesis of aromatic amino acids in Escherichia coli.
Topics: Amino Acids; Amino Acids, Aromatic; Caseins; Culture Media; Enzyme Inhibitors; Escherichia coli; Phenylalanine; Prephenate Dehydratase; Reverse Transcriptase Polymerase Chain Reaction; Serine; Tryptophan; Tyrosine | 2006 |
Stereo-structural prediction and IR-characteristic band assignment of amorphous protonated forms of homodipeptides (L)-Phe-(L)-Phe, (L)-Trp-(L)-Trp, (L)-Tyr-(L)-Tyr and the neutral - (L)-Trp-(L)-Trp. Ab initio approximation and solid-state linear-polarize
Topics: Dipeptides; Molecular Structure; Phenylalanine; Protons; Spectrophotometry, Infrared; Tryptophan; Tyrosine | 2006 |
Optimization of the solvent-tolerant Pseudomonas putida S12 as host for the production of p-coumarate from glucose.
Topics: Cinnamates; Coenzyme A Ligases; Coumaric Acids; Fermentation; Gene Deletion; Glucose; Phenylalanine; Propionates; Pseudomonas putida; Tyrosine | 2007 |
Cation-pi Interactions and oxidative effects on Cu+ and Cu2+ binding to Phe, Tyr, Trp, and His amino acids in the gas phase. Insights from first-principles calculations.
Topics: Algorithms; Amino Acids, Aromatic; Binding Sites; Cations, Divalent; Copper; Gases; Histidine; Hydrogen Bonding; Models, Molecular; Nitrogen; Oxidation-Reduction; Oxygen; Phenylalanine; Solvents; Spectrophotometry, Infrared; Tryptophan; Tyrosine | 2006 |
Roles of Tyr13 and Phe219 in the unique substrate specificity of pepsin B.
Topics: Animals; Binding Sites; Dogs; Humans; Hydrolysis; Kinetics; Models, Molecular; Mutation; Pepsin A; Phenylalanine; Protein Structure, Tertiary; Structural Homology, Protein; Substrate Specificity; Tyrosine | 2006 |
Mutational analysis of cytochrome b at the ubiquinol oxidation site of yeast complex III.
Topics: Aspartic Acid; Binding Sites; Crystallization; Cytochromes b; Cytochromes c; DNA Mutational Analysis; Electron Transport Complex III; Enzyme Activation; Enzyme Stability; Glutamic Acid; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Phenylalanine; Saccharomyces cerevisiae; Tyrosine; Ubiquinone | 2007 |
Design and evaluation of hydroxamate derivatives as metal-mediated inhibitors of a protein tyrosine kinase.
Topics: Cations, Divalent; Cobalt; Drug Design; Hydroxamic Acids; Phenylalanine; src-Family Kinases; Structure-Activity Relationship; Tyrosine | 2006 |
Redesigning the PheA domain of gramicidin synthetase leads to a new understanding of the enzyme's mechanism and selectivity.
Topics: Chorismate Mutase; Escherichia coli Proteins; Kinetics; Multienzyme Complexes; Mutagenesis, Site-Directed; Phenylalanine; Prephenate Dehydratase; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine | 2006 |
Modification of the active site of Mycobacterium tuberculosis KatG after disruption of the Met-Tyr-Trp cross-linked adduct.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Binding Sites; Catalase; Cross-Linking Reagents; Electron Spin Resonance Spectroscopy; Isoniazid; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Peroxidases; Phenylalanine; Protein Conformation; Recombinant Proteins; Spectrum Analysis, Raman; Tyrosine | 2007 |
Role of catechol structure in the adsorption and transformation reactions of L-DOPA in soils.
Topics: Adsorption; Catechin; Catechols; Hydrogen-Ion Concentration; Kinetics; Lactuca; Levodopa; Mucuna; Phenylalanine; Plant Growth Regulators; Soil; Structure-Activity Relationship; Tyrosine; Volcanic Eruptions | 2007 |
PAG-associated FynT regulates calcium signaling and promotes anergy in T lymphocytes.
Topics: Amino Acid Substitution; Animals; Calcium Signaling; Clonal Anergy; Intercellular Signaling Peptides and Proteins; Lymphocyte Activation; Membrane Microdomains; Membrane Proteins; Mice; Mice, Transgenic; Mutation; Phenylalanine; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-fyn; Receptors, Antigen, T-Cell; T-Lymphocytes; Tyrosine | 2007 |
Production of tyrosine from sucrose or glucose achieved by rapid genetic changes to phenylalanine-producing Escherichia coli strains.
Topics: Escherichia coli; Glucose; Phenylalanine; Sucrose; Tyrosine | 2007 |
A cation-pi interaction discriminates among sodium channels that are either sensitive or resistant to tetrodotoxin block.
Topics: Anesthetics, Local; Animals; Cations; Dose-Response Relationship, Drug; Electrophysiology; Fluorine; Molecular Conformation; Muscle Proteins; Oocytes; Phenylalanine; Protein Binding; Rats; Sodium Channels; Tetrahymena thermophila; Tetrodotoxin; Tyrosine; Xenopus | 2007 |
Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Animals; Glucuronosyltransferase; Humans; Isoenzymes; Kinetics; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sequence Homology, Amino Acid; Spodoptera; Substrate Specificity; Tyrosine | 2007 |
Tyrosine 330 in hSef is critical for the localization and the inhibitory effect on FGF signaling.
Topics: Cell Membrane; Fibroblast Growth Factors; Humans; Immunoassay; Immunoprecipitation; Mutation; Phenylalanine; Protein Serine-Threonine Kinases; ras Proteins; Receptors, Interleukin; Signal Transduction; Tyrosine | 2007 |
Diagnostic value of ultrastructural nerve examination in Charcot-Marie-Tooth disease: two CMT 1B cases with pseudo-recessive inheritance.
Topics: Adult; Asparagine; Charcot-Marie-Tooth Disease; Child; Consanguinity; Demyelinating Diseases; DNA Mutational Analysis; Female; Genes, Recessive; Humans; Microscopy, Electron, Transmission; Mutation; Myelin P0 Protein; Myelin Sheath; Peripheral Nerves; Phenylalanine; Serine; Tyrosine | 2007 |
Langmuir and Langmuir-Blodgett films of N-(4-octadecyloxy-2-hydroxybenzylidene) derivatives of amino acids.
Topics: Amino Acids; Benzylidene Compounds; Glycine; Microscopy; Models, Molecular; Phenylalanine; Spectroscopy, Fourier Transform Infrared; Stearic Acids; Tyrosine; Unilamellar Liposomes | 2007 |
Acute effects of enteral nutrition on protein turnover in adolescents with Crohn disease.
Topics: Adolescent; Blood Proteins; Crohn Disease; Enteral Nutrition; Female; Humans; Kinetics; Leucine; Male; Phenylalanine; Proteins; Splanchnic Circulation; Tyrosine | 2007 |
Salidroside production by hairy roots of Rhodiola sachalinensis obtained after transformation with Agrobacterium rhizogenes.
Topics: Agaricales; Aspergillus niger; Biomass; Ganoderma; Glucosides; Phenols; Phenylalanine; Phenylethyl Alcohol; Plant Growth Regulators; Plant Roots; Plants, Genetically Modified; Rhizobium; Rhodiola; Transformation, Genetic; Tyrosine | 2007 |
Assessment of chemical purity of 10B-enriched p-boronophenylalanine by high-performance liquid chromatography coupled on-line with inductively coupled plasma optical emission spectrometry.
Topics: Boron; Boron Compounds; Buffers; Chromatography, High Pressure Liquid; Drug Stability; Hydrogen-Ion Concentration; Phenylalanine; Radiation-Sensitizing Agents; Spectrophotometry; Spectrophotometry, Ultraviolet; Tyrosine | 2007 |
Leukemia inhibitory factor-induced phosphorylation of STAP-2 on tyrosine-250 is involved in its STAT3-enhancing activity.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Humans; Leukemia Inhibitory Factor; Mice; Phenylalanine; Phosphoproteins; Phosphorylation; STAT3 Transcription Factor; Tumor Cells, Cultured; Tyrosine | 2007 |
Structure-activity relationships of Leu-Enkephalin analog with (4-Carboxamido)phenylalanine substituted for tyrosine: a molecular dynamics study.
Topics: Analgesics, Opioid; Computer Simulation; Enkephalin, Leucine; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Phenylalanine; Receptors, Opioid, delta; Solutions; Structure-Activity Relationship; Tyrosine; Water | 2007 |
Methods for extracting biochemical information from bacterial Raman spectra: an explorative study on Cupriavidus metallidurans.
Topics: Acetyl Coenzyme A; Bacteria; Chemistry Techniques, Analytical; Citric Acid; Citric Acid Cycle; Cupriavidus; Models, Chemical; Phenylalanine; Spectrum Analysis, Raman; Tyrosine | 2007 |
Structurally conserved aromaticity of Tyr249 and Phe264 in helix 7 is important for toxicity of the Bacillus thuringiensis Cry4Ba toxin.
Topics: Amino Acid Sequence; Animals; Bacillus thuringiensis; Bacillus thuringiensis Toxins; Bacterial Proteins; Bacterial Toxins; Circular Dichroism; Crystallography, X-Ray; Culicidae; Endotoxins; Hemolysin Proteins; Hydrocarbons, Aromatic; Larva; Models, Molecular; Molecular Sequence Data; Mutant Proteins; Phenylalanine; Protein Processing, Post-Translational; Protein Structure, Secondary; Structural Homology, Protein; Structure-Activity Relationship; Tyrosine | 2007 |
c-Fms tyrosine 559 is a major mediator of M-CSF-induced proliferation of primary macrophages.
Topics: Amino Acid Substitution; Animals; Antimetabolites; Bromodeoxyuridine; Cell Division; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Mice; Mutant Chimeric Proteins; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Receptor, Macrophage Colony-Stimulating Factor; src-Family Kinases; Type C Phospholipases; Tyrosine | 2007 |
M-CSF regulates the cytoskeleton via recruitment of a multimeric signaling complex to c-Fms Tyr-559/697/721.
Topics: Actin Cytoskeleton; Amino Acid Substitution; Animals; Cell Movement; Cells, Cultured; Cytoskeleton; Macrophage Colony-Stimulating Factor; Macrophages; Mice; Mice, Inbred C57BL; Mutagenesis, Site-Directed; Osteoclasts; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-cbl; Receptor, Macrophage Colony-Stimulating Factor; Signal Transduction; src-Family Kinases; Tyrosine | 2007 |
Conformation of L-tyrosine studied by fluorescence-detected UV-UV and IR-UV double-resonance spectroscopy.
Topics: Computer Simulation; Electrons; Fluorescence; Models, Molecular; Molecular Conformation; Phenylalanine; Spectrum Analysis; Temperature; Tyrosine; Vibration | 2007 |
Fabrication and characterization of open-tubular CEC modified with tentacle-type metal-chelating polymer chains.
Topics: Allantoin; Capillary Electrochromatography; Chelating Agents; Creatinine; Electroosmosis; Epoxy Compounds; Hypoxanthine; Imino Acids; Methacrylates; Phenylalanine; Polymethacrylic Acids; Reproducibility of Results; Siloxanes; Tryptophan; Tyrosine | 2007 |
Value of a hydrogen bond in triosephosphate isomerase loop motion.
Topics: Animals; Binding Sites; Catalysis; Chickens; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Thermodynamics; Triose-Phosphate Isomerase; Tyrosine | 2007 |
N-terminal tyrosine modulation of the endocytic adaptor function of the beta-arrestins.
Topics: Adaptor Protein Complex mu Subunits; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Amino Acid Substitution; Animals; Arrestins; beta-Arrestins; Cell Line; Clathrin-Coated Vesicles; Humans; Kidney; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein Structure, Tertiary; Rats; src-Family Kinases; Transport Vesicles; Tyrosine | 2007 |
Electronic structure of the PYP chromophore in its native protein environment.
Topics: Amino Acid Sequence; Arginine; Bacterial Proteins; Cysteine; Glutamic Acid; Models, Molecular; Phenylalanine; Photoreceptors, Microbial; Threonine; Tyrosine; Valine | 2007 |
Only one of four oligopeptide transport systems mediates nitrogen nutrition in Staphylococcus aureus.
Topics: Amino Acid Sequence; Bacterial Proteins; Blotting, Western; Cell Division; Chromatography, High Pressure Liquid; Gene Expression Regulation, Bacterial; Membrane Transport Proteins; Molecular Sequence Data; Mutation; Nitrogen; Oligopeptides; Operon; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Tyrosine | 2007 |
A solid state 13C NMR, crystallographic, and quantum chemical investigation of phenylalanine and tyrosine residues in dipeptides and proteins.
Topics: Carbon Isotopes; Crystallography, X-Ray; Dipeptides; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Phenylalanine; Proteins; Quantum Theory; Static Electricity; Tyrosine | 2007 |
New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3 dimerization inhibitors.
Topics: Dimerization; Drug Design; Enzyme-Linked Immunosorbent Assay; Molecular Mimicry; Phenylalanine; STAT3 Transcription Factor; Tyrosine | 2007 |
Blockade of HERG K+ channel by an antihistamine drug brompheniramine requires the channel binding within the S6 residue Y652 and F656.
Topics: Brompheniramine; Cell Line; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Humans; Kinetics; Long QT Syndrome; Membrane Potentials; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Potassium Channel Blockers; Protein Subunits; Risk Assessment; Transfection; Tyrosine | 2008 |
Miconazole induces changes in actin cytoskeleton prior to reactive oxygen species induction in yeast.
Topics: Actins; Cytoskeleton; DNA, Fungal; Miconazole; Mutagenesis; Phenylalanine; Reactive Oxygen Species; Saccharomyces cerevisiae; Sequence Deletion; Tryptophan; Tyrosine | 2007 |
Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity.
Topics: Amino Acid Substitution; Animals; Cell Adhesion; Chlorocebus aethiops; COS Cells; DNA Mutational Analysis; Epidermal Growth Factor; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Mutation; Neoplasm Proteins; Phenylalanine; Phosphorylation; rac GTP-Binding Proteins; src-Family Kinases; Transfection; Tyrosine | 2007 |
The crucial step in ether phospholipid biosynthesis: structural basis of a noncanonical reaction associated with a peroxisomal disorder.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Amino Acid Substitution; Animals; Binding Sites; Catalysis; Chondrodysplasia Punctata, Rhizomelic; Conserved Sequence; Crystallography, X-Ray; Dictyostelium; Dimerization; Flavin-Adenine Dinucleotide; Histidine; Humans; Hydrogen Bonding; Lipid Metabolism, Inborn Errors; Models, Biological; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peroxisomal Disorders; Phenylalanine; Phospholipid Ethers; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Spectrum Analysis, Raman; Substrate Specificity; Tyrosine | 2007 |
o-Nitrotyrosine and p-iodophenylalanine as spectroscopic probes for structural characterization of SH3 complexes.
Topics: Circular Dichroism; Fluorescence Resonance Energy Transfer; Peptides; Phenylalanine; Protein Binding; Proteins; src Homology Domains; Tryptophan; Tyrosine | 2007 |
Complexation of Al(III) by aromatic amino acids in the gas phase.
Topics: Alanine; Aluminum; Amino Acids; Cations; Metals; Models, Chemical; Models, Molecular; Molecular Conformation; Nitrogen; Oxygen; Phenylalanine; Software; Solvents; Tryptophan; Tyrosine | 2007 |
Role of tyrosine-34 in the anion binding equilibria in manganese(II) superoxide dismutases.
Topics: Amino Acid Substitution; Anions; Electron Spin Resonance Spectroscopy; Enzyme Activation; Manganese; Oxidation-Reduction; Phenylalanine; Protein Binding; Rhodobacter capsulatus; Spectrophotometry; Substrate Specificity; Superoxide Dismutase; Temperature; Tyrosine | 2007 |
D- and L-[123I]-2-I-phenylalanine show a long tumour retention compared with D- and L-[123I]-2-I-tyrosine in R1M rhabdomyosarcoma tumour-bearing Wag/Rij rats.
Topics: Animals; Iodine Radioisotopes; Pharmacokinetics; Phenylalanine; Rats; Rhabdomyosarcoma; Tyrosine | 2007 |
Combinations of two amino acids (Ala40 and Phe75 or Ser40 and Tyr75) in the coat protein of apple chlorotic leaf spot virus are crucial for infectivity.
Topics: Alanine; Amino Acid Sequence; DNA Primers; Flexiviridae; Malus; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Plant Diseases; Plant Leaves; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Deletion; Sequence Homology, Amino Acid; Serine; Tyrosine; Virus Replication | 2007 |
Electronic spectroscopy and solvatochromism in the chromophore of GFP and the Y66F mutant.
Topics: Electronics; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Molecular Structure; Mutation; Phenylalanine; Protons; Solvents; Spectrophotometry; Temperature; Tyrosine | 2007 |
Phenylalanine biosynthesis in Arabidopsis thaliana. Identification and characterization of arogenate dehydratases.
Topics: Amino Acids, Dicarboxylic; Arabidopsis; Arabidopsis Proteins; Cloning, Molecular; Cyclohexanecarboxylic Acids; Cyclohexenes; Escherichia coli; Gene Expression; Humans; Hydro-Lyases; Kinetics; Phenylalanine; Phylogeny; Prephenate Dehydratase; Protein Structure, Tertiary; Recombinant Proteins; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2007 |
Characterization of rice tryptophan decarboxylases and their direct involvement in serotonin biosynthesis in transgenic rice.
Topics: Aromatic-L-Amino-Acid Decarboxylases; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Molecular Structure; Oryza; Phenylalanine; Plants, Genetically Modified; Recombinant Proteins; Serotonin; Substrate Specificity; Tryptamines; Tyramine; Tyrosine; Tyrosine Decarboxylase | 2007 |
Conformation-specific spectroscopy and photodissociation of cold, protonated tyrosine and phenylalanine.
Topics: Algorithms; Cold Temperature; Mass Spectrometry; Molecular Conformation; Phenylalanine; Photochemistry; Protons; Spectrophotometry, Infrared; Tyrosine; Ultraviolet Rays | 2007 |
Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine.
Topics: Codon; Peptide Chain Elongation, Translational; Peptide Elongation Factor Tu; Phenylalanine; Phenylalanine-tRNA Ligase; RNA Editing; RNA, Transfer, Amino Acyl; Time Factors; Tyrosine | 2007 |
Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027.
Topics: Aminoglycosides; Antibiotics, Antineoplastic; Carrier Proteins; Catalysis; Chlorine; Chromatography, High Pressure Liquid; Enediynes; Flavins; Hydrogen-Ion Concentration; Molecular Structure; Phenylalanine; Tyrosine | 2007 |
Dose-response effects of free fatty acids on amino acid metabolism and ureagenesis.
Topics: Adult; Dose-Response Relationship, Drug; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Forearm; Glucose Clamp Technique; Heparin; Human Growth Hormone; Humans; Lipid Metabolism; Lipolysis; Male; Phenylalanine; Pyrazines; Somatostatin; Tyrosine; Urea | 2008 |
Novel roles in human MD-2 of phenylalanines 121 and 126 and tyrosine 131 in activation of Toll-like receptor 4 by endotoxin.
Topics: Cell Line; Culture Media; Endotoxins; Humans; Lipopolysaccharide Receptors; Lipopolysaccharides; Lymphocyte Antigen 96; Mutant Proteins; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Solubility; Structure-Activity Relationship; Toll-Like Receptor 4; Transfection; Tritium; Tyrosine | 2008 |
Determination of enantiomeric compositions of analytes using novel fluorescent chiral molecular micelles and steady state fluorescence measurements.
Topics: Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Glucose; Micelles; Molecular Structure; Phenylalanine; Serine; Spectrometry, Fluorescence; Stereoisomerism; Surface-Active Agents; Tartrates; Tryptophan; Tyrosine | 2008 |
Substrate binding and formation of an occluded state in the leucine transporter.
Topics: Amino Acid Transport Systems; Arginine; Aspartic Acid; Binding Sites; Biological Transport; Computer Simulation; Crystallography, X-Ray; Extracellular Space; Ions; Leucine; Phenylalanine; Protein Conformation; Sodium; Substrate Specificity; Tyrosine | 2008 |
Mutation of Tyr-218 to Phe in Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase: effects on bioelectronic interface performance.
Topics: Alcohol Oxidoreductases; Biosensing Techniques; Electrochemistry; Mutagenesis, Site-Directed; NAD; Phenylalanine; Thermoanaerobacter; Tyrosine | 2007 |
Aromatic dipeptides and their salts--solid-state linear-dichroic infrared (IR-LD) spectral analysis and ab initio calculations.
Topics: Dipeptides; Models, Chemical; Molecular Conformation; Phenylalanine; Salts; Spectrophotometry, Infrared; Tyrosine | 2008 |
Effects of acute tyrosine/phenylalanine depletion on the selective processing of smoking-related cues and the relative value of cigarettes in smokers.
Topics: Adult; Amino Acids; Cross-Over Studies; Cues; Dopamine; Double-Blind Method; Female; Humans; Male; Multivariate Analysis; Phenylalanine; Reaction Time; Smoking; Smoking Cessation; Tyrosine | 2008 |
Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Animals, Newborn; Biomarkers; Chromatography, High Pressure Liquid; Deoxyguanosine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Female; Hypoxia; Male; Oxidative Stress; Oxygen; Oxygen Inhalation Therapy; Phenylalanine; Reactive Oxygen Species; Respiration, Artificial; Swine; Tandem Mass Spectrometry; Time Factors; Tyrosine | 2007 |
Complex assembly mechanism and an RNA-binding mode of the human p14-SF3b155 spliceosomal protein complex identified by NMR solution structure and functional analyses.
Topics: Amino Acid Sequence; Amino Acid Substitution; Binding Sites; Cell Nucleus; DNA, Complementary; Glutathione Transferase; Histidine; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Leucine; Models, Molecular; Molecular Sequence Data; Nuclear Localization Signals; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Phosphoproteins; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Ribonucleoprotein, U2 Small Nuclear; Ribonucleoproteins; RNA Splicing; RNA Splicing Factors; Sequence Homology, Amino Acid; Spliceosomes; Trypsin; Tyrosine; Valine | 2008 |
Compromised E-cadherin adhesion and epithelial barrier function with activation of G protein-coupled receptors is rescued by Y-to-F mutations in beta-catenin.
Topics: Amino Acid Substitution; Animals; beta Catenin; Cadherins; Cell Adhesion; Dogs; Electric Impedance; Epithelial Cells; Histamine; Humans; L Cells; Mice; Mutation; Oligopeptides; Phenylalanine; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, PAR-2; Receptors, Histamine H1; Transfection; Tyrosine | 2008 |
[2,3-(13)C]-labeling of aromatic residues--getting a head start in the magic-angle-spinning NMR assignment of membrane proteins.
Topics: Amino Acids, Aromatic; Bacterial Outer Membrane Proteins; Carbon Isotopes; Escherichia coli Proteins; Isotope Labeling; Magnetic Resonance Spectroscopy; Membrane Proteins; Phenylalanine; Porins; Tyrosine | 2008 |
Resolution of racemic phenylalanine, tyrosine, and tryptophan.
Topics: Phenylalanine; Tryptophan; Tyrosine | 1949 |
Serum phenylalanine in patients post trauma and with sepsis correlate to neopterin concentrations.
Topics: Adult; Aged; Biopterins; Female; Follow-Up Studies; Humans; Male; Middle Aged; Molecular Structure; Neopterin; Oxidative Stress; Phenylalanine; Phenylalanine Hydroxylase; Reproducibility of Results; Sepsis; Tyrosine; Wounds and Injuries | 2008 |
Amino acid residues involved in stereoselective inhibition of cholinesterases with bambuterol.
Topics: Acetylcholinesterase; Alanine; Amino Acid Substitution; Amino Acids; Animals; Asparagine; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Glutamine; Isoleucine; Leucine; Mice; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Stereoisomerism; Terbutaline; Tyrosine | 2008 |
Physiological effects of anti-TRAP protein activity and tRNA(Trp) charging on trp operon expression in Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Culture Media; Gene Expression Regulation, Bacterial; Kinetics; Models, Biological; Mutation; Operon; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; RNA-Binding Proteins; RNA, Transfer, Trp; Transcription Factors; Transcription, Genetic; Tryptophan; Tyrosine | 2008 |
Bitterness in almonds.
Topics: Amygdalin; Carbon Radioisotopes; Cellulases; Flowers; Fruit; Glucosyltransferases; Microsomes; Nitriles; Phenylalanine; Plant Exudates; Prunus; Tyrosine | 2008 |
Role of alphaPhe-291 residue in the phosphate-binding subdomain of catalytic sites of Escherichia coli ATP synthase.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine Diphosphate; Aluminum; ATP Synthetase Complexes; Azides; Base Sequence; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Enzyme Inhibitors; Escherichia coli; Fluorine; Hydrolysis; Mutation; Phenylalanine; Phosphates; Phosphorylation; Tyrosine | 2008 |
Interaction of pepsin with aromatic amino acids and their derivatives immobilized to Sepharose.
Topics: Amino Acids, Aromatic; Animals; Chromatography, Affinity; Ethylenediamines; Pepsin A; Phenylalanine; Sepharose; Sulfones; Swine; Tyrosine | 2008 |
Alternative strategy for converting an inverting glycoside hydrolase into a glycosynthase.
Topics: Amino Acid Substitution; Glycoside Hydrolases; Glycosyltransferases; Kinetics; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Phenylalanine; Substrate Specificity; Time Factors; Tyrosine; Xylosidases | 2008 |
Replacement of tyrosine residues by phenylalanine in cytochrome P450cam alters the formation of Cpd II-like species in reactions with artificial oxidants.
Topics: Camphor 5-Monooxygenase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Oxidants; Phenylalanine; Porphyrins; Protons; Spectrophotometry; Tyrosine | 2008 |
Exploring inhibitor binding at the S' subsites of cathepsin L.
Topics: Arginine; Binding Sites; Biphenyl Compounds; Cathepsin L; Cathepsins; Crystallography, X-Ray; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Models, Molecular; Phenylalanine; Protein Binding; Static Electricity; Tyrosine | 2008 |
On the structural role of the aromatic residue environment of the chlorophyll a in the cytochrome b6f complex.
Topics: Chlorophyll; Chlorophyll A; Cytochrome b6f Complex; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Spectrum Analysis; Synechococcus; Tyrosine | 2008 |
[Simultaneous resolution and determination of tyrosine, tryptophan and phenylalanine by alternating penalty trilinear decomposition algorithm coupled with 3D emission-excitation matrix fluorometry].
Topics: Algorithms; Chlorhexidine; Phenylalanine; Plant Leaves; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2007 |
Coupling of complex aromatic ring vibrations to solvent through hydrogen bonds: effect of varied on-ring and off-ring hydrogen-bonding substitutions.
Topics: Amino Acids, Aromatic; Biogenic Amines; Dopamine; Epinephrine; Hydrogen Bonding; Levodopa; Models, Chemical; Norepinephrine; Phenylalanine; Quantum Theory; Solvents; Spectrophotometry, Infrared; Temperature; Tyrosine; Vibration | 2008 |
A novel missense mutation pattern of the GCH1 gene in dopa-responsive dystonia.
Topics: Child; Dopamine Agents; Dystonia; Female; GTP Cyclohydrolase; Heterozygote; Humans; Levodopa; Mutation, Missense; Phenylalanine; Tyrosine | 2007 |
Single-conformation ultraviolet and infrared spectroscopy of model synthetic foldamers: beta-peptides Ac-beta3-hPhe-NHMe and Ac-beta3-hTyr-NHMe.
Topics: Models, Molecular; Peptides; Phenylalanine; Protein Conformation; Protein Folding; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thermodynamics; Tyrosine | 2008 |
G-protein-coupled receptor-mediated traffic of Na,K-ATPase to the plasma membrane requires the binding of adaptor protein 1 to a Tyr-255-based sequence in the alpha-subunit.
Topics: Adaptor Protein Complex 1; Angiotensin II; Animals; Cell Line; Cell Membrane; Enzyme Activation; Mutation; Opossums; Phenylalanine; Protein Binding; Protein Conformation; Rats; Sodium-Potassium-Exchanging ATPase; Transfection; Tyrosine | 2008 |
Role of aromatic amino acids in receptor binding activity and subunit assembly of the cytolethal distending toxin of Aggregatibacter actinomycetemcomitans.
Topics: Amino Acid Sequence; Amino Acid Substitution; Amino Acids, Aromatic; Animals; Bacterial Toxins; Binding Sites; CHO Cells; Cricetinae; Cricetulus; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Subunits; Receptors, Cell Surface; Structure-Activity Relationship; Tyrosine | 2008 |
Influence of amino acids, organic solvents and surfactants for phenylalanine ammonia lyase activity in recombinant Escherichia coli.
Topics: Amino Acids; Biotechnology; Escherichia coli; Organic Chemicals; Phenylalanine; Phenylalanine Ammonia-Lyase; Recombinant Proteins; Solvents; Surface-Active Agents; Tyrosine | 2008 |
Analysis of protein-based media commonly found in paintings using synchronous fluorescence spectroscopy combined with multivariate statistical analysis.
Topics: Amino Acids; Multivariate Analysis; Paintings; Phenylalanine; Proteins; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2008 |
Site-directed mutagenesis of conserved C-terminal tyrosine and tryptophan residues of PsbO, the photosystem II manganese-stabilizing protein, alters its activity and fluorescence properties.
Topics: Circular Dichroism; Conserved Sequence; Manganese; Mutagenesis, Site-Directed; Peptide Fragments; Phenylalanine; Photosystem II Protein Complex; Plant Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spinacia oleracea; Tryptophan; Tyrosine | 2008 |
Engineering substrate preference in subtilisin: structural and kinetic analysis of a specificity mutant.
Topics: Acylation; Amino Acid Sequence; Bacillus; Bacterial Proteins; Binding Sites; Binding, Competitive; Kinetics; Models, Molecular; Mutation; Phenylalanine; Protein Binding; Protein Engineering; Protein Structure, Tertiary; Substrate Specificity; Subtilisin; Thermodynamics; Tyrosine | 2008 |
Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
Topics: Amino Acids, Aromatic; Chromatography; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Methyldopa; Phenylalanine; Reproducibility of Results; Stereoisomerism; Tyrosine | 2008 |
Structural basis for controlling the dimerization and stability of the WW domains of an atypical subfamily.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Motifs; Amino Acid Sequence; Amino Acid Substitution; Cell Adhesion Molecules; Cell Adhesion Molecules, Neuronal; Cell Cycle Proteins; Dimerization; Genetic Variation; Guanylate Kinases; Hot Temperature; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Molecular Sequence Data; Molecular Weight; Phenylalanine; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Serine; Tryptophan; Tyrosine | 2008 |
In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.
Topics: Amino Acyl-tRNA Synthetases; Carbon Isotopes; Escherichia coli; Fatty Acid Synthases; Isotope Labeling; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Phenylpropionates; Plasmids; Protein Engineering; Protein Structure, Tertiary; Proteins; Tyrosine | 2008 |
Tryptophan-accelerated electron flow through proteins.
Topics: Azurin; Copper; Crystallography, X-Ray; Electrons; Energy Transfer; Kinetics; Ligands; Models, Chemical; Mutant Proteins; Oxidation-Reduction; Phenylalanine; Pseudomonas aeruginosa; Rhenium; Spectrum Analysis; Thermodynamics; Tryptophan; Tyrosine | 2008 |
Effect of pH on aqueous phenylalanine studied using a 265-nm pulsed light-emitting diode.
Topics: Carbon; Equipment Design; Hydrogen-Ion Concentration; Light; Methanol; Molecular Conformation; Phenylalanine; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Water | 2008 |
Arylation of Phe and Tyr side chains of unprotected peptides by a Suzuki-Miyaura reaction in water.
Topics: Enkephalin, Leucine; Iodoproteins; Onium Compounds; Peptides; Phenylalanine; Pyridines; Tyrosine | 2008 |
Phenylalanine and tyrosine kinetics in compensated liver cirrhosis: effects of meal ingestion.
Topics: Adult; Case-Control Studies; Deuterium; Eating; Fasting; Humans; Hydroxylation; Infusions, Intravenous; Kinetics; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Protein Biosynthesis; Severity of Illness Index; Tyrosine; Up-Regulation | 2008 |
Origins of enhanced proton transport in the Y7F mutant of human carbonic anhydrase II.
Topics: Amino Acid Substitution; Bicarbonates; Binding Sites; Carbon Dioxide; Carbonic Anhydrase III; Catalysis; Computer Simulation; Crystallography, X-Ray; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Phenylalanine; Protons; Solvents; Tyrosine; Water; Zinc | 2008 |
The extra C-terminal tail is involved in the conformation, stability changes and the N/C-domain interactions of the calmodulin-like protein from pearl oyster Pinctada fucata.
Topics: Animals; Calcium; Calmodulin; Circular Dichroism; Electrophoretic Mobility Shift Assay; Fluorescence; Phenylalanine; Pinctada; Protein Binding; Protein Conformation; Protein Denaturation; Protein Structure, Tertiary; Recombinant Proteins; Tyrosine | 2008 |
Evidence for protein radical-mediated nuclear tunneling in fatty acid alpha-oxygenase.
Topics: Carbon; Catalysis; Deuterium; Fatty Acids; Free Radicals; Hydrogen; Kinetics; Oryza; Oxidation-Reduction; Oxygen; Oxygenases; Phenylalanine; Proteins; Spectrum Analysis; Thermodynamics; Tyrosine | 2008 |
Replacement of a phenylalanine by a tyrosine in the active site confers fructose-6-phosphate aldolase activity to the transaldolase of Escherichia coli and human origin.
Topics: Amino Acid Sequence; Catalytic Domain; Cell-Free System; Escherichia coli; Fructose-Bisphosphate Aldolase; Humans; Hydrogen Bonding; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Sequence Homology, Amino Acid; Transaldolase; Tyrosine | 2008 |
Serum phenylalanine concentrations in patients with ovarian carcinoma correlate with concentrations of immune activation markers and of isoprostane-8.
Topics: Biomarkers; Biomarkers, Tumor; Cystadenocarcinoma; Endometrial Neoplasms; Female; HIV Infections; Humans; Isoprostanes; Lymphocyte Activation; Neoplasm Staging; Neopterin; Ovarian Neoplasms; Oxidative Stress; Phenylalanine; Receptors, Tumor Necrosis Factor, Type II; Sepsis; Tyrosine; Uterine Neoplasms | 2008 |
Aromatic amino acid-dependent expression of indole-3-pyruvate decarboxylase is regulated by TyrR in Enterobacter cloacae UW5.
Topics: Amino Acid Sequence; Amino Acids, Aromatic; Bacterial Proteins; Base Sequence; Carboxy-Lyases; Electrophoretic Mobility Shift Assay; Enterobacter cloacae; Gene Expression Regulation, Bacterial; Indoleacetic Acids; Mutation; Phenylalanine; Promoter Regions, Genetic; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Sequence Alignment; Sequence Analysis, DNA; Tryptophan; Tyrosine | 2008 |
Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway.
Topics: Coenzyme A Ligases; Coumaric Acids; Culture Media; Curcumin; DNA, Recombinant; Escherichia coli; Genes, Plant; Genetic Engineering; Genetic Enhancement; Industrial Microbiology; Lithospermum; Oryza; Phenylalanine; Phenylalanine Ammonia-Lyase; Rhodotorula; Tyrosine | 2008 |
Mutational analysis of vaccinia virus mRNA cap (guanine-N7) methyltransferase reveals essential contributions of the N-terminal peptide that closes over the active site.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Conserved Sequence; DNA Mutational Analysis; Methylation; Methyltransferases; Molecular Sequence Data; Multienzyme Complexes; Nucleotidyltransferases; Peptides; Phenylalanine; Phosphoric Monoester Hydrolases; Structure-Activity Relationship; Tyrosine; Vaccinia virus; Viral Proteins | 2008 |
Site-specific incorporation of chemical probes into proteins for NMR.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Carbon Isotopes; Codon, Nonsense; Fatty Acid Synthases; Fluorine; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Tyrosine | 2008 |
Dissociations of copper(II)-containing complexes of aromatic amino acids: radical cations of tryptophan, tyrosine, and phenylalanine.
Topics: Amino Acids, Aromatic; Copper; Organometallic Compounds; Phenylalanine; Protons; Thermodynamics; Tryptophan; Tyrosine | 2008 |
Chromatography of amino acids on starch columns; separation of phenylalanine, leucine, isoleucine, methionine, tyrosine, and valine.
Topics: Amino Acids; Chromatography; Isoleucine; Leucine; Methionine; Phenylalanine; Starch; Tyrosine; Valine | 1948 |
Factors affecting the excretion of metabolites of phenylalanine and tyrosine in alkaptanuria.
Topics: Biochemical Phenomena; Biological Transport; Body Fluids; Phenylalanine; Tyrosine; Urine | 1948 |
Structural characterization of the tunnels of Mycobacterium tuberculosis truncated hemoglobin N from molecular dynamics simulations.
Topics: Algorithms; Bacterial Proteins; Catalytic Domain; Computational Biology; Computer Simulation; Glutamine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Mycobacterium tuberculosis; Oxygen; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Time Factors; Truncated Hemoglobins; Tyrosine | 2009 |
Noninvasive imaging of protein metabolic labeling in single human cells using stable isotopes and Raman microscopy.
Topics: Deuterium; HeLa Cells; Humans; Methionine; Phenylalanine; Proteins; Spectrum Analysis, Raman; Tyrosine | 2008 |
The effect of the mode of delivery on maternal-neonatal interleukin-6, biogenic amine and their precursor amino acid concentrations.
Topics: Adult; Amino Acids, Aromatic; Antioxidants; Biogenic Amines; Blood Pressure; Catecholamines; Cesarean Section; Creatine Kinase; Delivery, Obstetric; Female; Fetal Blood; Heart Rate; Humans; Infant, Newborn; Interleukin-6; Lipids; Liver; Natural Childbirth; Phenylalanine; Pregnancy; Serotonin; Tryptophan; Tyrosine; Young Adult | 2008 |
A single aromatic residue in transcriptional repressor protein KorA is critical for cooperativity with its co-regulator KorB.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; DNA; Gene Expression Regulation, Bacterial; Molecular Sequence Data; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Plasmids; Protein Binding; Protein Interaction Mapping; Protein Structure, Tertiary; Repressor Proteins; Transcription, Genetic; Tyrosine | 2008 |
Application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the analysis of stable isotope enrichments of phenylalanine and tyrosine.
Topics: Chromatography, Liquid; Humans; Phenylalanine; Reproducibility of Results; Tandem Mass Spectrometry; Tyrosine | 2009 |
Structural and functional studies of Bacillus stearothermophilus serine hydroxymethyltransferase: the role of Asn(341), Tyr(60) and Phe(351) in tetrahydrofolate binding.
Topics: Amino Acid Sequence; Asparagine; Geobacillus stearothermophilus; Glycine Hydroxymethyltransferase; Kinetics; Leucovorin; Phenylalanine; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Tyrosine | 2009 |
Human fetal amino acid metabolism at term gestation.
Topics: Adult; Blood Flow Velocity; Carbon Isotopes; Cesarean Section; Female; Fetal Blood; Fetal Proteins; Fetus; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Hydroxylation; Infant; Infant, Newborn; Male; Nutritional Requirements; Phenylalanine; Pregnancy; Prenatal Nutritional Physiological Phenomena; Regional Blood Flow; Tyrosine; Ultrasonography | 2009 |
Low-temperature studies of electron transfer to the M side of YFH reaction centers from Rhodobacter capsulatus.
Topics: Amino Acid Substitution; Bacteriochlorophylls; Electron Transport; Kinetics; Models, Molecular; Molecular Conformation; Mutation; Phenylalanine; Photochemistry; Photosynthetic Reaction Center Complex Proteins; Rhodobacter capsulatus; Spectrophotometry; Thermodynamics; Tyrosine | 2009 |
Tyrosine and phenylalanine are synthesized within the plastids in Arabidopsis.
Topics: Arabidopsis; Arabidopsis Proteins; Blotting, Western; Gene Expression Profiling; Gene Expression Regulation, Plant; Isoenzymes; Phenylalanine; Plant Leaves; Plastids; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Subcellular Fractions; Transcription, Genetic; Tyrosine | 2009 |
Identification and determination of the intra- and extracellular aminopeptidase activity by synthetic L-Ala-, L-Tyr-, and L-Phe-beta-napthylamide.
Topics: Alanine; Alginates; Amides; Aminopeptidases; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Extracellular Space; Glucose; Glutaral; Intracellular Space; Papaver; Pectins; Phenylalanine; Polysorbates; Tyrosine | 2008 |
Phenylketonuria: High plasma phenylalanine decreases cerebral protein synthesis.
Topics: Adolescent; Adult; Cerebrum; Female; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Positron-Emission Tomography; Protein Biosynthesis; Tyrosine | 2009 |
Biochemical markers associated with executive function in adolescents with early and continuously treated phenylketonuria.
Topics: Adolescent; Biomarkers; Child; Cognition; Humans; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Psychomotor Performance; Tyrosine | 2009 |
Formation of complex AChR aggregates in vitro requires alpha-dystrobrevin.
Topics: Animals; Cells, Cultured; Dystrophin-Associated Proteins; Gene Expression Regulation; Green Fluorescent Proteins; Immunoprecipitation; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Confocal; Muscle Cells; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation; Phenylalanine; Protein Isoforms; Protein Transport; Receptors, Cholinergic; Tyrosine | 2009 |
Gas-phase IR spectroscopy of deprotonated amino acids.
Topics: Amino Acids; Anions; Aspartic Acid; Cysteine; Gases; Glutamic Acid; Phenylalanine; Protons; Serine; Spectrophotometry; Spectrophotometry, Infrared; Tyrosine | 2009 |
A unique dual activity amino acid hydroxylase in Toxoplasma gondii.
Topics: Amino Acid Sequence; Animals; Conserved Sequence; Fibroblasts; Gene Expression Regulation, Developmental; Genes, Protozoan; Humans; Molecular Sequence Data; Phenylalanine; Phenylalanine Hydroxylase; Protozoan Proteins; Pterins; Rats; Recombinant Fusion Proteins; RNA, Messenger; RNA, Protozoan; Sequence Alignment; Sequence Homology, Amino Acid; Species Specificity; Substrate Specificity; Toxoplasma; Tyrosine; Tyrosine 3-Monooxygenase | 2009 |
Assessment of mitochondrial respiratory chain function in hyperphenylalaninaemia.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Cell Line, Tumor; Cells, Cultured; Culture Media; Electron Transport; Female; Humans; Lactic Acid; Male; Middle Aged; Mitochondrial Diseases; Phenylalanine; Phenylketonurias; Pyruvic Acid; Tremor; Tyrosine; Ubiquinone; Young Adult | 2009 |
Determination of branched chain amino acids, methionine, phenylalanine, tyrosine and alpha-keto acids in plasma and dried blood samples using HPLC with fluorescence detection.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Amino Acids, Branched-Chain; Blood Stains; Chromatography, High Pressure Liquid; Female; Fluorescence; Humans; Infant, Newborn; Keto Acids; Male; Methionine; Phenylalanine; Reference Values; Tyrosine | 2009 |
Hydration of protonated aromatic amino acids: phenylalanine, tryptophan, and tyrosine.
Topics: Binding Sites; Mass Spectrometry; Models, Molecular; Molecular Structure; Phenylalanine; Quantum Theory; Thermodynamics; Tryptophan; Tyrosine; Water | 2009 |
Characterization of putative tryptophan monooxygenase from Ralstonia solanacearum [corrected].
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Bacterial Proteins; Deamination; Decarboxylation; Enzyme Precursors; Escherichia coli; Flavoproteins; Kinetics; Methionine; Models, Structural; Molecular Sequence Data; Phenylalanine; Ralstonia solanacearum; Sequence Alignment; Substrate Specificity; Transformation, Bacterial; Tryptophan; Tryptophan Hydroxylase; Tyrosine | 2009 |
Intramolecular addition of cysteine thiyl radical to phenylalanine and tyrosine in model peptides, Phe (CysS*) and Tyr(CysS*): a computational study.
Topics: Computer Simulation; Cysteine; Models, Molecular; Molecular Conformation; Peptides; Phenylalanine; Quantum Theory; Tyrosine; Water | 2009 |
A new HLA-C allele: Cw*0819.
Topics: Alleles; Amino Acid Substitution; HLA-C Antigens; Humans; Phenylalanine; Sequence Analysis, DNA; Tyrosine | 2009 |
Gas phase protonation thermochemistry of phenylalanine and tyrosine.
Topics: Computer Simulation; Gases; Kinetics; Models, Chemical; Molecular Structure; Phenylalanine; Protons; Thermodynamics; Tyrosine | 2009 |
Beta-cyclodextrin-modified CdSe/ZnS quantum dots for sensing and chiroselective analysis.
Topics: Adamantane; beta-Cyclodextrins; Cadmium Compounds; Electron Transport; Fluorescence Resonance Energy Transfer; Phenylalanine; Quantum Dots; Selenium Compounds; Stereoisomerism; Sulfides; Toluene; Tyrosine; Zinc Compounds | 2009 |
Regulation of H3K4 trimethylation via Cps40 (Spp1) of COMPASS is monoubiquitination independent: implication for a Phe/Tyr switch by the catalytic domain of Set1.
Topics: DNA-Binding Proteins; Histone-Lysine N-Methyltransferase; Histones; Humans; Infant; Lysine; Methylation; Models, Molecular; Phenylalanine; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tyrosine; Ubiquitination | 2009 |
Phenylalanine 35 and tyrosine 82 are involved in the uptake and release of ligand by porcine odorant-binding protein.
Topics: Amino Acid Sequence; Animals; Anthracenes; Fluorescent Dyes; Ligands; Models, Molecular; Peptide Mapping; Phenylalanine; Protein Binding; Receptors, Odorant; Spectrometry, Fluorescence; Swine; Tyrosine | 2009 |
Effects of L-histidine depletion and L-tyrosine/L-phenylalanine depletion on sensory and motor processes in healthy volunteers.
Topics: Adolescent; Adult; Choice Behavior; Cross-Over Studies; Cues; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Histidine; Humans; Male; Phenylalanine; Photic Stimulation; Psychomotor Performance; Reaction Time; Stereoisomerism; Tyrosine; Young Adult | 2009 |
Five amino acids in the innermost cavity of the substrate binding cleft of organic cation transporter 1 interact with extracellular and intracellular corticosterone.
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Amino Acids; Animals; Corticosterone; Dose-Response Relationship, Drug; Female; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Models, Molecular; Molecular Sequence Data; Oocytes; Organic Cation Transporter 1; Patch-Clamp Techniques; Phenylalanine; Point Mutation; Protein Structure, Secondary; Rats; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine; Xenopus laevis | 2009 |
Role of the sixth transmembrane segment of domain IV of the cockroach sodium channel in the action of sodium channel blocker insecticides.
Topics: Animals; Cockroaches; Ion Channel Gating; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Oxazines; Patch-Clamp Techniques; Phenylalanine; Protein Structure, Tertiary; Semicarbazones; Sodium Channel Blockers; Time Factors; Tyrosine; Xenopus laevis | 2009 |
Role of cetyltrimethylammonium bromide (cationic surfactant) on the tryptophan-MnO4(-) reaction.
Topics: Catalysis; Cetrimonium; Cetrimonium Compounds; Manganese Compounds; Oxidation-Reduction; Oxides; Phenylalanine; Surface-Active Agents; Tryptophan; Tyrosine | 2009 |
Topological switching between an alpha-beta parallel protein and a remarkably helical molten globule.
Topics: Apoproteins; Conserved Sequence; Flavodoxin; Models, Chemical; Phenylalanine; Protein Folding; Protein Structure, Quaternary; Protein Structure, Secondary; Thermodynamics; Tyrosine | 2009 |
Controlled release from modified amino acid hydrogels governed by molecular size or network dynamics.
Topics: Amino Acids; Coloring Agents; Diffusion; Fluorenes; Gels; Gluconates; Hydrogels; Hydrogen-Ion Concentration; Microscopy, Electron, Scanning; Models, Chemical; Molecular Conformation; Particle Size; Phenylalanine; Rheology; Tyrosine | 2009 |
[Effects of precursor feeding and fungal elicitors on secondary metabolits in cell suspension culture of Cistanche deserticola].
Topics: Cell Culture Techniques; Cell Division; Cells, Cultured; Cistanche; Culture Media; Dose-Response Relationship, Drug; Glycosides; Phenylalanine; Tyrosine | 2009 |
Forearm and leg amino acid metabolism in the basal state and during combined insulin and amino acid stimulation after a 3-day fast.
Topics: Adult; Amino Acids; Fasting; Forearm; Humans; Insulin; Leg; Male; Phenylalanine; Radioactive Tracers; Regional Blood Flow; Tyrosine | 2009 |
Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction center.
Topics: Amino Acid Substitution; Bacteriochlorophylls; Crystallography, X-Ray; Cytochromes; Hyphomicrobiaceae; Oxidation-Reduction; Phenylalanine; Pheophytins; Photosynthetic Reaction Center Complex Proteins; Protein Multimerization; Spectrophotometry; Tyrosine | 2009 |
Structure and function of a complex between chorismate mutase and DAHP synthase: efficiency boost for the junior partner.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Amino Acid Sequence; Catalytic Domain; Chorismate Mutase; Cloning, Molecular; Corynebacterium glutamicum; Crystallography, X-Ray; Enzyme Activation; Malates; Models, Molecular; Molecular Sequence Data; Mycobacterium tuberculosis; Phenylalanine; Sequence Alignment; Shikimic Acid; Tyrosine | 2009 |
Thyroid hormone non-genomically suppresses Src thereby stimulating osteocalcin expression in primary mouse calvarial osteoblasts.
Topics: Animals; Cells, Cultured; Mice; Osteoblasts; Osteocalcin; Phenylalanine; Skull; src-Family Kinases; Triiodothyronine; Tyrosine | 2009 |
Plasma tryptophan and tyrosine levels are independent risk factors for delirium in critically ill patients.
Topics: Aged; Amino Acid Transport System L; Analysis of Variance; Critical Illness; Delirium; Disease Progression; Female; Humans; Logistic Models; Male; Markov Chains; Middle Aged; Phenylalanine; Pilot Projects; Predictive Value of Tests; Regression Analysis; Risk Assessment; Risk Factors; Severity of Illness Index; Tennessee; Time Factors; Tryptophan; Tyrosine | 2009 |
Genetic and biochemical identification of the chorismate mutase from Corynebacterium glutamicum.
Topics: Allosteric Regulation; Chorismate Mutase; Chorismic Acid; Cloning, Molecular; Corynebacterium glutamicum; Cyclohexanecarboxylic Acids; Cyclohexenes; Dimerization; Escherichia coli; Gene Expression; Genes, Essential; Phenylalanine; Phylogeny; Protein Binding; Protein Interaction Mapping; Sequence Homology, Amino Acid; Tyrosine | 2009 |
Application of SAIL phenylalanine and tyrosine with alternative isotope-labeling patterns for protein structure determination.
Topics: Carbon Isotopes; Escherichia coli Proteins; Isoenzymes; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Peptidylprolyl Isomerase; Phenylalanine; Protein Conformation; Proteins; Tyrosine | 2010 |
Enhancement of L-tryptophan 5-hydroxylation activity by structure-based modification of L-phenylalanine 4-hydroxylase from Chromobacterium violaceum.
Topics: Amino Acid Sequence; Animals; Catalase; Cattle; Chromobacterium; Hydroxylation; Kinetics; Molecular Sequence Data; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Protein Conformation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Tryptophan; Tyrosine | 2009 |
Factors that affect oxygen activation and coupling of the two redox cycles in the aromatization reaction catalyzed by NikD, an unusual amino acid oxidase.
Topics: Amino Acid Oxidoreductases; Catalysis; Crystallography, X-Ray; Flavoproteins; Ligands; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Phenylalanine; Picolinic Acids; Streptomyces; Tyrosine | 2009 |
The production of intrinsically labeled milk protein provides a functional tool for human nutrition research.
Topics: Absorption; Animals; Carbon Isotopes; Cattle; Deuterium; Dietary Proteins; Digestion; Female; Humans; Isotope Labeling; Leucine; Male; Middle Aged; Milk; Milk Proteins; Muscle Proteins; Nutritional Physiological Phenomena; Phenylalanine; Research; Tyrosine | 2009 |
Amphiphilic lauryl ester derivatives from aromatic amino acids: significance of chemical architecture in aqueous aggregation properties.
Topics: Calorimetry, Differential Scanning; Electron Spin Resonance Spectroscopy; Hydrophobic and Hydrophilic Interactions; Laurates; Micelles; Molecular Conformation; Phenylalanine; Tyrosine; Water | 2009 |
Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy.
Topics: Amino Acid Substitution; Anemia, Sickle Cell; Crystallography, X-Ray; Hemoglobin, Sickle; Hemolysis; Humans; Kinetics; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Subunits; Spectrum Analysis, Raman; Tryptophan; Tyrosine | 2009 |
RET mutation Tyr791Phe: the genetic cause of different diseases derived from neural crest.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Carcinoma, Medullary; Child; Disease; Family; Female; Genetic Association Studies; Germ-Line Mutation; Hirschsprung Disease; Humans; Male; Middle Aged; Multiple Endocrine Neoplasia Type 2a; Neural Crest; Phenylalanine; Polymorphism, Single Nucleotide; Proto-Oncogene Mas; Proto-Oncogene Proteins c-ret; Thyroid Neoplasms; Tyrosine; Young Adult | 2009 |
Biosynthesis of coelenterazine in the deep-sea copepod, Metridia pacifica.
Topics: Animals; Copepoda; Imidazoles; Luminescent Agents; Phenylalanine; Pyrazines; Tyrosine | 2009 |
Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour.
Topics: Animals; Cell Line; Depression; Disease Models, Animal; Down-Regulation; Gene Knock-In Techniques; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phenylalanine; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Tyrosine | 2009 |
Determination of phenylalanine and tyrosine in plasma and dried blood samples using HPLC with fluorescence detection.
Topics: Adult; Chromatography, High Pressure Liquid; Female; Fluorescence; Humans; Male; Middle Aged; Phenylalanine; Tyrosine | 2009 |
Plasma phenylalanine level in dopa-responsive dystonia.
Topics: Analysis of Variance; Dihydroxyphenylalanine; Dopamine Agents; Dystonia; GTP Cyclohydrolase; Humans; Phenylalanine; Tyrosine | 2009 |
AMINO ACID COMPOSITION OF HIGHLY PURIFIED VIRAL PARTICLES OF INFLUENZA A AND B.
Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Glutamates; Glycine; Histidine; Humans; Influenza, Human; Isoleucine; Leucine; Lysine; Methionine; Orthomyxoviridae; Phenylalanine; Proline; Serine; Threonine; Tryptophan; Tyrosine; Valine; Virion | 1947 |
Structural models for interactions between the 20S proteasome and its PAN/19S activators.
Topics: Adenosine Triphosphatases; Archaeal Proteins; Crystallography, X-Ray; Endopeptidases; Enzyme Activators; Humans; Models, Molecular; Phenylalanine; Proteasome Endopeptidase Complex; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Tyrosine | 2010 |
Structure and dynamics of aromatic residues in spider silk: 2D carbon correlation NMR of dragline fibers.
Topics: Animals; Carbon Isotopes; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Structure, Tertiary; Silk; Spiders; Tyrosine | 2010 |
A single Phe54Tyr substitution improves the catalytic activity and thermostability of Trigonopsis variabilis D-amino acid oxidase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Catalysis; Cephalosporins; D-Amino-Acid Oxidase; Enzyme Stability; Fungal Proteins; Humans; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Protein Structure, Tertiary; Saccharomycetales; Sequence Alignment; Temperature; Tyrosine | 2010 |
Unresponsiveness to tetrahydrobiopterin of phenylalanine hydroxylase deficiency.
Topics: Adolescent; Biopterins; Child; Child, Preschool; Genotype; Humans; Infant; Mutation; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Statistics, Nonparametric; Tyrosine; Young Adult | 2010 |
Increased blood phenylalanine to tyrosine ratio in HIV-1 infection and correction following effective antiretroviral therapy.
Topics: Aged; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Female; HIV Infections; HIV-1; Humans; Lymphocyte Count; Male; Middle Aged; Neopterin; Phenylalanine; Phenylalanine Hydroxylase; RNA, Viral; Tyrosine | 2010 |
Rational design of aminoacyl-tRNA synthetase specific for p-acetyl-L-phenylalanine.
Topics: Crystallography, X-Ray; Escherichia coli; Methanococcus; Mutation; Phenylalanine; Protein Biosynthesis; Protein Conformation; Protein Engineering; Tyrosine; Tyrosine-tRNA Ligase | 2010 |
Interrupted hydrogen/deuterium exchange reveals the stable core of the remarkably helical molten globule of alpha-beta parallel protein flavodoxin.
Topics: Algorithms; Amino Acid Substitution; Azotobacter vinelandii; Bacterial Proteins; Deuterium Exchange Measurement; Flavodoxin; Hydrophobic and Hydrophilic Interactions; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Phenylalanine; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Tyrosine | 2010 |
A negative regulatory role for Y1111 on the Tie-2 RTK.
Topics: Cell Line; Humans; Phenylalanine; Phosphorylation; Point Mutation; Receptor, TIE-2; Tyrosine | 2010 |
A new biomarker of protein oxidation degree and site using angiotensin as the target by MS.
Topics: Angiotensins; Biomarkers; Chromatography, High Pressure Liquid; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Phenylalanine; Proteins; Tandem Mass Spectrometry; Tyrosine | 2010 |
Positions of Trp codons in the leader peptide-coding region of the at operon influence anti-trap synthesis and trp operon expression in Bacillus licheniformis.
Topics: 4-Aminobenzoic Acid; Bacillus; Bacterial Proteins; Base Sequence; Gene Expression Regulation, Bacterial; Mutation; Operon; Phenylalanine; Polymerase Chain Reaction; RNA-Binding Proteins; Transcription Factors; Transcription, Genetic; Tryptophan; Tyrosine | 2010 |
Synthesis of the conformationally constrained tyrosine analogues, (R)- and (S)-5-hydroxy-2-aminoindan-2-carboxylic acids.
Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Dipeptides; Indans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Phenylalanine; Stereoisomerism; Tyrosine | 2010 |
Glucosylthioureidocalix[4]arenes: Synthesis, conformations and gas phase recognition of amino acids.
Topics: Amino Acids; Deuterium; Gases; Hydrogen; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tryptophan; Tyrosine | 2010 |
Structural contributions of delta class glutathione transferase active-site residues to catalysis.
Topics: Binding Sites; Catalysis; Catalytic Domain; Crystallography, X-Ray; Glutathione Transferase; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Recombinant Proteins; Substrate Specificity; Tyrosine | 2010 |
Block of the human ether-a-go-go-related gene (hERG) K+ channel by the antidepressant desipramine.
Topics: Animals; Antidepressive Agents, Tricyclic; Desipramine; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Inhibitory Concentration 50; Long QT Syndrome; Mutation; Oocytes; Phenylalanine; Protein Structure, Tertiary; Tyrosine; Xenopus | 2010 |
Replacement of Phe274 with conserved residue Tyr274 for reactive center loop expulsion in antithrombin.
Topics: Amino Acid Substitution; Animals; Antithrombin Proteins; Catalytic Domain; Cell Line; Humans; Mutagenesis, Site-Directed; Mutation, Missense; Phenylalanine; Protein Structure, Secondary; Recombinant Proteins; Spodoptera; Tyrosine | 2011 |
RNAi suppression of Arogenate Dehydratase1 reveals that phenylalanine is synthesized predominantly via the arogenate pathway in petunia petals.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; Flowers; Gene Expression Regulation, Plant; Genes, Plant; Hydro-Lyases; Petunia; Phenylalanine; Phylogeny; Plant Proteins; Plants, Genetically Modified; RNA Interference; RNA, Plant; Shikimic Acid; Tyrosine; Volatile Organic Compounds | 2010 |
The phenylalanine and tyrosine contents of chicks and eggs.
Topics: Amino Acids; Animals; Chickens; Eggs; Phenylalanine; Tyrosine | 1947 |
The utilization of phenylalanine and tyrosine derivatives by mutant strains of Escherichia coli.
Topics: Escherichia coli; Phenylalanine; Tyrosine | 1947 |
Preparation of d-tyrosine, its acetyl derivatives, and d-3,4-dihydroxyphenylalanine.
Topics: Dihydroxyphenylalanine; Phenylalanine; Tyrosine | 1946 |
Growth retardation and corneal vascularization with tyrosine and phenylalanine in a purified diet.
Topics: Cornea; Deficiency Diseases; Diet; Phenylalanine; Tyrosine | 1946 |
The partial replacement of dietary phenylalanine by tyrosine for purposes of growth.
Topics: Alanine; Diet; Intercellular Signaling Peptides and Proteins; Phenylalanine; Tyrosine | 1946 |
Prevention of phenylalanine synthesis by tyrosine.
Topics: Phenylalanine; Tyrosine | 1947 |
Characterization of the Pseudomonas aeruginosa transcriptional response to phenylalanine and tyrosine.
Topics: Bacterial Proteins; Base Sequence; Electrophoretic Mobility Shift Assay; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Phenylalanine; Promoter Regions, Genetic; Protein Binding; Pseudomonas aeruginosa; Trans-Activators; Tyrosine | 2010 |
Charge effects in the selection of NPF motifs by the EH domain of EHD1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Binding Sites; Calcium-Binding Proteins; Calorimetry; Circular Dichroism; Endocytosis; Humans; Intracellular Signaling Peptides and Proteins; Magnetic Resonance Spectroscopy; Mammals; Models, Molecular; Peptide Fragments; Peptides; Phenylalanine; Phosphoproteins; Protein Conformation; Tyrosine; Vesicular Transport Proteins | 2010 |
Important groups of alkaloids derived biosynthetically from phenylalanine and tyrosine. Preface.
Topics: Alkaloids; Amaryllidaceae Alkaloids; Erythrina; Galantamine; Phenylalanine; Plant Structures; Tyrosine | 2010 |
Construction of an L-phenylalanine-producing tyrosine-prototrophic Escherichia coli strain using tyrA ssrA-like tagged alleles.
Topics: Amino Acid Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; Escherichia coli; Molecular Sequence Data; Phenylalanine; Prephenate Dehydrogenase; Time Factors; Tyrosine | 2010 |
A preliminary investigation of the role of the phenylalanine:tyrosine ratio in children with early and continuously treated phenylketonuria: toward identification of "safe" levels.
Topics: Adolescent; Analysis of Variance; Child; Cognition Disorders; Executive Function; Humans; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Severity of Illness Index; Surveys and Questionnaires; Tyrosine | 2010 |
Approaches to the assignment of (19)F resonances from 3-fluorophenylalanine labeled calmodulin using solution state NMR.
Topics: Amino Acid Sequence; Animals; Calmodulin; Crystallography, X-Ray; Fluorine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Phenylalanine; Solutions; Trypsin; Tyrosine; Xenopus Proteins | 2010 |
Structure-selective modification of aromatic side chains with dirhodium metallopeptide catalysts.
Topics: Amino Acid Sequence; Biocatalysis; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Protein Conformation; Rhodium; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2010 |
Coarse-grained potential models for phenyl-based molecules: I. Parametrization using experimental data.
Topics: Benzene; Models, Chemical; Molecular Dynamics Simulation; Phenylalanine; Thermodynamics; Tyrosine | 2010 |
Activity of the acyl-CoA synthetase ACSL6 isoforms: role of the fatty acid Gate-domains.
Topics: Adenosine Triphosphate; Coenzyme A Ligases; Humans; Isoenzymes; Octoxynol; Phenylalanine; Protein Structure, Tertiary; Tyrosine | 2010 |
A capillary electrophoresis method for the determination of selected biogenic amines and amino acids in mammalian decomposition fluid.
Topics: Animals; Biogenic Amines; Capillaries; Electrolytes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Methanol; Models, Chemical; Phenylalanine; Swine; Time Factors; Tryptamines; Tryptophan; Tyramine; Tyrosine | 2010 |
High molecular size humic substances enhance phenylpropanoid metabolism in maize (Zea mays L.).
Topics: Gene Expression Regulation, Plant; Humic Substances; Magnetic Resonance Spectroscopy; Phenols; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Proteins; Spectroscopy, Fourier Transform Infrared; Tyrosine; Zea mays | 2010 |
Adeno-associated virus serotype 6 capsid tyrosine-to-phenylalanine mutations improve gene transfer to skeletal muscle.
Topics: Alkaline Phosphatase; Animals; Capsid Proteins; Dependovirus; DNA Copy Number Variations; Gene Dosage; Gene Expression; Genes, Reporter; Genetic Therapy; Genetic Vectors; Luciferases, Firefly; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Mutation; Phenylalanine; Transduction, Genetic; Transgenes; Tyrosine | 2010 |
How does proteinase 3 interact with lipid bilayers?
Topics: Binding Sites; Cations; Cell Membrane; Choline; Dimyristoylphosphatidylcholine; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lipid Bilayers; Molecular Dynamics Simulation; Myeloblastin; Phenylalanine; Phosphatidylglycerols; Static Electricity; Tryptophan; Tyrosine | 2010 |
Tyrosine requirement during the rapid catch-up growth phase of recovery from severe childhood undernutrition.
Topics: Carbon Isotopes; Female; Humans; Infant; Infant Food; Infant Nutrition Disorders; Male; Malnutrition; Nutritional Requirements; Phenylalanine; Tyrosine | 2010 |
Identification and characterization of the maize arogenate dehydrogenase gene family.
Topics: Amino Acid Sequence; Amino Acids; Endosperm; Gene Expression Regulation, Plant; Lysine; Molecular Sequence Data; Mutation; Phenotype; Phenylalanine; Prephenate Dehydrogenase; Seeds; Sequence Alignment; Tyrosine; Zea mays; Zein | 2010 |
Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity.
Topics: Acids; Amino Acid Sequence; Amino Acids; Animals; Binding, Competitive; CHO Cells; Chromatography, High Pressure Liquid; Cricetinae; Cricetulus; Dynorphins; Methylation; Models, Chemical; Molecular Structure; Peptides; Phenylalanine; Protein Binding; Rats; Receptors, Opioid, kappa; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship; Tryptophan; Tyrosine | 2011 |
Pleiotropic physiological consequences of feedback-insensitive phenylalanine biosynthesis in Arabidopsis thaliana.
Topics: Animals; Arabidopsis; Arabidopsis Proteins; Biocatalysis; Biosynthetic Pathways; Drug Resistance; Feedback, Physiological; Glucosinolates; Host-Parasite Interactions; Hydro-Lyases; Immunity, Innate; Molecular Structure; Moths; Mutation; Phenylalanine; Plant Diseases; Plant Leaves; Plants, Genetically Modified; Salt Tolerance; Tryptophan; Tyrosine | 2010 |
Nociceptin and its natural and specifically-modified fragments: Structural studies.
Topics: Amino Acid Sequence; Amino Acids; Histidine; Molecular Sequence Data; Nociceptin; Opioid Peptides; Peptide Fragments; Phenylalanine; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tyrosine | 2010 |
Single turnover kinetics of tryptophan hydroxylase: evidence for a new intermediate in the reaction of the aromatic amino acid hydroxylases.
Topics: Amino Acids, Aromatic; Kinetics; Mixed Function Oxygenases; Phenylalanine; Substrate Specificity; Tryptophan Hydroxylase; Tyrosine | 2010 |
New insights into tetrahydrobiopterin pharmacodynamics from Pah enu1/2, a mouse model for compound heterozygous tetrahydrobiopterin-responsive phenylalanine hydroxylase deficiency.
Topics: Animals; Biopterins; Breath Tests; Disease Models, Animal; Dose-Response Relationship, Drug; Heterozygote; Mice; Mice, Mutant Strains; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Treatment Outcome; Tyrosine | 2010 |
Mass spectrometric identification of key proteolytic cleavage sites in statherin affecting mineral homeostasis and bacterial binding domains.
Topics: Amino Acid Sequence; Arginine; Bacteria; Binding Sites; Chlorides; Chromatography, High Pressure Liquid; Chromatography, Liquid; Glycine; Homeostasis; Humans; Hydrolysis; Mass Spectrometry; Minerals; Molecular Sequence Data; Parotid Gland; Peptides; Phenylalanine; Protein Binding; Saliva; Salivary Proteins and Peptides; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tyrosine; Zinc Compounds | 2010 |
Partitioning of new carbon as ¹¹C in Nicotiana tabacum reveals insight into methyl jasmonate induced changes in metabolism.
Topics: Acetates; Carbon Isotopes; Cyclopentanes; Ecosystem; Nicotiana; Oxylipins; Phenols; Phenylalanine; Plant Growth Regulators; Plant Leaves; Shikimic Acid; Time Factors; Tryptophan; Tyrosine | 2010 |
Tyrosine monitoring in children with early and continuously treated phenylketonuria: results of an international practice survey.
Topics: Adolescent; Australasia; Biomarkers; Child; Child, Preschool; Cognition; Dietary Supplements; Europe; Executive Function; Health Care Surveys; Humans; Infant; Infant, Newborn; Intelligence Tests; Neuropsychological Tests; North America; Phenylalanine; Phenylketonurias; Practice Patterns, Physicians'; Predictive Value of Tests; Surveys and Questionnaires; Time Factors; Treatment Outcome; Tyrosine | 2010 |
Phenylalanine hydroxylase (PAH) from the lower eukaryote Leishmania major.
Topics: Amino Acid Sequence; Animals; Binding Sites; Conserved Sequence; Culture Media; DNA, Protozoan; Gene Knockout Techniques; Genetic Complementation Test; Hydroxylation; Leishmania major; Leishmaniasis, Cutaneous; Mice; Microbial Viability; Molecular Sequence Data; Phenylalanine; Phenylalanine Hydroxylase; Protein Structure, Tertiary; Sequence Alignment; Sequence Analysis, DNA; Tryptophan; Tyrosine; Virulence | 2011 |
Two-dimensional surface properties of PEO-PPO-PEO triblock copolymer film at the air/water interface in the absence and presence of Tyr-Phe dipeptide, Val-Tyr-Val tripeptide, SDS and stearic acid.
Topics: Adsorption; Air; Epoxy Compounds; Peptides; Phenylalanine; Polyethylene Glycols; Polymers; Sodium Dodecyl Sulfate; Stearic Acids; Surface Properties; Temperature; Thermodynamics; Tyrosine; Valine; Water | 2011 |
First hyperpolarizability of the natural aromatic amino acids tryptophan, tyrosine, and phenylalanine and the tripeptide lysine-tryptophan-lysine determined by hyper-Rayleigh scattering.
Topics: Amino Acids; Oligopeptides; Phenylalanine; Scattering, Radiation; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2010 |
1H NMR spectroscopic investigations on the conformation of amphiphilic aromatic amino acid derivatives in solution: effect of chemical architecture of amphiphiles and polarity of solvent medium.
Topics: Deuterium Oxide; Dimethyl Sulfoxide; Esters; Hydrophobic and Hydrophilic Interactions; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phenylalanine; Solutions; Solvents; Tyrosine | 2010 |
The redox--biochemistry of human hair pigmentation.
Topics: Animals; Antioxidants; Catecholamines; Cyclic AMP; Hair; Hair Follicle; Humans; Hydrogen Peroxide; Mice; Models, Biological; Monophenol Monooxygenase; Oxidation-Reduction; Phenylalanine; Pigmentation; Pro-Opiomelanocortin; Signal Transduction; Tyrosine | 2011 |
Site-directed mutagenesis of the χ subunit of DNA polymerase III and single-stranded DNA-binding protein of E. coli reveals key residues for their interaction.
Topics: Binding Sites; DNA Polymerase III; DNA-Binding Proteins; Escherichia coli Proteins; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Tyrosine | 2011 |
Tolerance of larvae of Drosophila for amino acids; tyrosine, phenylalanine, and alanine.
Topics: Alanine; Amino Acids; Animals; Drosophila; Larva; Phenylalanine; Tyrosine | 1945 |
The tyrosine O-prenyltransferase SirD catalyzes O-, N-, and C-prenylations.
Topics: Aspergillus fumigatus; Dimethylallyltranstransferase; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenylalanine; Prenylation; Tryptophan; Tyrosine | 2011 |
Vibrational analysis of amino acids and short peptides in hydrated media. VIII. Amino acids with aromatic side chains: L-phenylalanine, L-tyrosine, and L-tryptophan.
Topics: Models, Theoretical; Peptides; Phenylalanine; Solutions; Solvents; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Vibration; Water | 2010 |
Partial biopterin deficiency disturbs postnatal development of the dopaminergic system in the brain.
Topics: Alcohol Oxidoreductases; Animals; Biopterins; Corpus Striatum; Dopamine; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Neurologic Mutants; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Substantia Nigra; Tyrosine; Tyrosine 3-Monooxygenase | 2011 |
Divergence in enzyme regulation between Caenorhabditis elegans and human tyrosine hydroxylase, the key enzyme in the synthesis of dopamine.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Cloning, Molecular; Dopamine; Genetic Variation; Humans; Mixed Function Oxygenases; Molecular Sequence Data; Phenylalanine; Phosphorylation; Recombinant Proteins; Substrate Specificity; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 2011 |
Enantiospecific synthesis of 2-[18F]fluoro-L-phenylalanine and 2-[18F]fluoro-L-tyrosine by isotopic exchange.
Topics: Fluorine Radioisotopes; Hydrolysis; Molecular Structure; Phenylalanine; Stereoisomerism; Tyrosine | 2011 |
The equilibrium of phosphatidylcholine-amino acid system in monolayer at the air/water interface.
Topics: Air; Amino Acids; Phenylalanine; Phosphatidylcholines; Surface Tension; Tyrosine; Water | 2011 |
Prephenate aminotransferase directs plant phenylalanine biosynthesis via arogenate.
Topics: Carbon Cycle; Humans; Hydro-Lyases; Phenylalanine; Plant Proteins; Plants; Transaminases; Tyrosine | 2011 |
Rate of phenylalanine hydroxylation in healthy school-aged children.
Topics: Animals; Child; Diet; Female; Humans; Hydroxylation; Male; Oxidation-Reduction; Phenylalanine; Radioisotopes; Tyrosine | 2011 |
Deletion of the mouse homolog of KCNAB2, a gene linked to monosomy 1p36, results in associative memory impairments and amygdala hyperexcitability.
Topics: Acoustic Stimulation; Amygdala; Analysis of Variance; Animals; Association Learning; Behavior, Animal; Conditioning, Classical; Electric Stimulation; Electroencephalography; Evoked Potentials, Auditory, Brain Stem; Exploratory Behavior; Fear; In Vitro Techniques; Membrane Potentials; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Patch-Clamp Techniques; Phenylalanine; Point Mutation; Shaker Superfamily of Potassium Channels; Tyrosine | 2011 |
Spectroscopic analyses on interaction of o-Vanillin-D-Phenylalanine, o-Vanillin-L-Tyrosine and o-Vanillin-L-Levodopa Schiff Bases with bovine serum albumin (BSA).
Topics: Animals; Benzaldehydes; Cattle; Dopamine Agents; Levodopa; Molecular Structure; Phenylalanine; Schiff Bases; Serum Albumin, Bovine; Tyrosine | 2011 |
Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum.
Topics: Amino Acids; Binding Sites; Biocatalysis; Carboxylic Acids; Coenzyme A; Coenzyme A Ligases; Fungal Proteins; Kinetics; Models, Chemical; Models, Molecular; Molecular Structure; Mutagenesis, Site-Directed; Penicillium chrysogenum; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Substrate Specificity; Tyrosine | 2011 |
Effect of metal Ions (Ni²⁺, Cu²⁺ and Zn²⁺) and water coordination on the structure of L-phenylalanine, L-tyrosine, L-tryptophan and their zwitterionic forms.
Topics: Cations; Chemistry, Organic; Copper; Gases; Models, Molecular; Molecular Conformation; Nickel; Phenylalanine; Quantum Theory; Thermodynamics; Tryptophan; Tyrosine; Water; Zinc | 2011 |
Impact of protein coingestion on muscle protein synthesis during continuous endurance type exercise.
Topics: Amino Acids; Beverages; Bicycling; Biopsy; Cyclic AMP-Dependent Protein Kinases; Diet; Dietary Carbohydrates; Dietary Proteins; Humans; Lactic Acid; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Physical Endurance; TOR Serine-Threonine Kinases; Tyrosine; Young Adult | 2011 |
Comparison of fluorescence reagents for simultaneous determination of hydroxylated phenylalanine and nitrated tyrosine by high-performance liquid chromatography with fluorescence detection.
Topics: Chromatography, High Pressure Liquid; Fluorescent Dyes; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Limit of Detection; Peroxynitrous Acid; Phenylalanine; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Fluorescence; Tyrosine | 2012 |
The ncgl1108 (PheP (Cg)) gene encodes a new L-Phe transporter in Corynebacterium glutamicum.
Topics: Carbon Radioisotopes; Corynebacterium glutamicum; Gene Knockout Techniques; Kinetics; Membrane Transport Proteins; Phenylalanine; Staining and Labeling; Tryptophan; Tyrosine | 2011 |
Queuosine deficiency in eukaryotes compromises tyrosine production through increased tetrahydrobiopterin oxidation.
Topics: Animals; Hep G2 Cells; Humans; Mice; Nucleoside Q; Oxidation-Reduction; Pentosyltransferases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pterins; RNA, Transfer; Tetrahydrofolate Dehydrogenase; Tyrosine | 2011 |
Synthesis and comparative biological evaluation of L- and D-isomers of 18F-labeled fluoroalkyl phenylalanine derivatives as tumor imaging agents.
Topics: Animals; Biological Transport; Cell Line, Tumor; Fluorine Radioisotopes; Glioma; Phenylalanine; Positron-Emission Tomography; Rats; Stereoisomerism; Tyrosine | 2011 |
Partitioning of amino acids in the aqueous biphasic system containing the water-miscible ionic liquid 1-butyl-3-methylimidazolium bromide and the water-structuring salt potassium citrate.
Topics: Amino Acids; Citric Acid; Imidazoles; Ionic Liquids; Leucine; Phenylalanine; Potassium Citrate; Tryptophan; Tyrosine; Valine; Water | 2011 |
Conformational constraints in angiotensin IV to probe the role of Tyr², Pro⁵ and Phe⁶.
Topics: Aminopeptidases; Angiotensin II; Animals; Biocatalysis; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; HEK293 Cells; Humans; Molecular Structure; Phenylalanine; Proline; Protein Conformation; Spectrophotometry, Atomic; Substrate Specificity; Tyrosine | 2011 |
Density functional theory study of conformation-dependent properties of neutral and radical cationic L-tyrosine and L-tryptophan.
Topics: Cations; Chemistry, Physical; Free Radicals; Hydrogen Bonding; Hydrogen-Ion Concentration; Models, Molecular; Molecular Conformation; Phenylalanine; Quantum Theory; Static Electricity; Thermodynamics; Tryptophan; Tyrosine | 2011 |
Development of L-tryptophan production strains by defined genetic modification in Escherichia coli.
Topics: Anthranilate Synthase; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Feedback, Physiological; Gene Knockout Techniques; Multienzyme Complexes; Mutagenesis, Site-Directed; Phenylalanine; Plasmids; Prephenate Dehydratase; Repressor Proteins; Tryptophan; Tryptophanase; Tyrosine | 2011 |
Topography of tyrosine residues and their involvement in peroxidation of polyunsaturated cardiolipin in cytochrome c/cardiolipin peroxidase complexes.
Topics: Animals; Cardiolipins; Computer Simulation; Cytochromes c; Electron Spin Resonance Spectroscopy; Heme; Horses; Hydrogen Peroxide; Iron; Magnetic Resonance Spectroscopy; Mitochondrial Membranes; Mutation; Myocardium; Oxygen; Oxygenases; Peroxidase; Peroxidases; Phenylalanine; Tyrosine | 2011 |
Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell lines.
Topics: Animals; Capsid; Cell Line; Dependovirus; Epithelial Cells; Flow Cytometry; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Mice; Phenylalanine; Photoreceptor Cells; Recombinant Fusion Proteins; Retina; Transformation, Genetic; Transgenes; Tyrosine; Vision, Ocular | 2011 |
Three aromatic amino acids in gastric juice as potential biomarkers for gastric malignancies.
Topics: Amino Acids, Aromatic; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Gastric Juice; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenylalanine; Spectrometry, Fluorescence; Stomach Neoplasms; Tryptophan; Tyrosine | 2011 |
Designing and engineering of a site-specific incorporation of a keto group in uricase.
Topics: Amino Acyl-tRNA Synthetases; Animals; Candida; Escherichia coli; Genetic Vectors; Methanococcus; Models, Molecular; Mutant Proteins; Mutation; Phenylalanine; Protein Engineering; Rabbits; Serum; Structural Homology, Protein; Substrate Specificity; Tyrosine; Urate Oxidase; Uric Acid | 2011 |
Partial impairment of c-Ret at tyrosine 1062 accelerates age-related hearing loss in mice.
Topics: Animals; Disease Models, Animal; Genetic Carrier Screening; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mutation; Phenylalanine; Phosphorylation; Presbycusis; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-ret; Spiral Ganglion; Tyrosine; Up-Regulation | 2012 |
Photoinduced intramolecular tryptophan oxidation and excited-state behavior of [Re(L-AA)(CO)3(α-diimine)](+) (L = pyridine or imidazole, AA = tryptophan, tyrosine, phenylalanine).
Topics: Carbon Monoxide; Imidazoles; Imines; Molecular Structure; Organometallic Compounds; Oxidation-Reduction; Phenylalanine; Photochemical Processes; Pyridines; Quantum Theory; Rhenium; Stereoisomerism; Tryptophan; Tyrosine | 2011 |
Amino acid components of lees in salmon fish sauce are tyrosine and phenylalanine.
Topics: Animals; Fish Products; Phenylalanine; Salmo salar; Salmon; Tyrosine | 2011 |
Upregulation of CREB-mediated transcription enhances both short- and long-term memory.
Topics: Analysis of Variance; Animals; Bacterial Proteins; Behavior, Animal; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Carbazoles; Cell Line, Transformed; Chlorocebus aethiops; Conditioning, Classical; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Discrimination, Psychological; Electric Stimulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Fear; Fluorescence Resonance Energy Transfer; Hippocampus; Indole Alkaloids; Long-Term Potentiation; Luminescent Proteins; Maze Learning; Memory, Long-Term; Memory, Short-Term; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Patch-Clamp Techniques; Phenylalanine; Rats; RNA, Messenger; Social Behavior; Transfection; Tyrosine; Up-Regulation | 2011 |
Chiral capillary electrophoresis-mass spectrometry of 3,4-dihydroxyphenylalanine: evidence for its enantioselective metabolism in PC-12 nerve cells.
Topics: Animals; beta-Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis, Capillary; Mass Spectrometry; PC12 Cells; Phenylalanine; Rats; Stereoisomerism; Tyrosine | 2011 |
Substrate specifity profiling of the Aspergillus fumigatus proteolytic secretome reveals consensus motifs with predominance of Ile/Leu and Phe/Tyr.
Topics: Amino Acid Motifs; Amino Acid Sequence; Amino Acids; Aspergillus fumigatus; Consensus Sequence; Humans; Isoleucine; Leucine; Peptide Hydrolases; Peptide Library; Phenylalanine; Species Specificity; Substrate Specificity; Tyrosine | 2011 |
Arabidopsis thaliana NIP7;1: an anther-specific boric acid transporter of the aquaporin superfamily regulated by an unusual tyrosine in helix 2 of the transport pore.
Topics: Amino Acid Substitution; Aquaporins; Arabidopsis; Arabidopsis Proteins; Boric Acids; Carrier Proteins; Conserved Sequence; Flowers; Gene Expression Regulation, Plant; Multigene Family; Organ Specificity; Phenylalanine; Pollen; Protein Structure, Secondary; Tyrosine | 2011 |
Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation.
Topics: Animals; Arthritis, Experimental; Autoimmunity; Blotting, Western; Cell Cycle Proteins; Cell Proliferation; Encephalomyelitis, Autoimmune, Experimental; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Female; Gene Knock-In Techniques; Inflammation; Lymphocyte Activation; Mice; Mice, Transgenic; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phosphorylation; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tyrosine | 2011 |
Netrin-1-induced local β-actin synthesis and growth cone guidance requires zipcode binding protein 1.
Topics: Actinin; Analysis of Variance; Animals; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cell Movement; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Female; Gene Expression Regulation; Green Fluorescent Proteins; Growth Cones; Male; Mice; Mice, Knockout; Mutation; Nerve Growth Factors; Netrin-1; Neurons; Phenylalanine; Pregnancy; Pseudopodia; Rats; Rats, Sprague-Dawley; RNA, Messenger; Statistics, Nonparametric; Time Factors; Transfection; Tumor Suppressor Proteins; Tyrosine | 2011 |
Identification of genes in the phenylalanine metabolic pathway by ectopic expression of a MYB transcription factor in tomato fruit.
Topics: Amino Acids, Dicarboxylic; Cyclohexanecarboxylic Acids; Cyclohexenes; Fruit; Gene Expression Regulation, Plant; Humans; Metabolic Networks and Pathways; Microarray Analysis; Molecular Sequence Data; Molecular Structure; Petunia; Phenylalanine; Phenylpyruvic Acids; Phylogeny; Plant Extracts; Plant Proteins; Plants, Genetically Modified; Proto-Oncogene Proteins c-myb; Recombinant Fusion Proteins; Solanum lycopersicum; Transaminases; Tyrosine; Volatile Organic Compounds | 2011 |
Metabolomics reveals differential levels of oral metabolites in HIV-infected patients: toward novel diagnostic targets.
Topics: Adult; Anti-HIV Agents; Case-Control Studies; Chromatography, Liquid; Female; Gas Chromatography-Mass Spectrometry; HIV Infections; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; Mouth; Phenylalanine; Tyrosine | 2013 |
Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids.
Topics: Amino Acid Substitution; Amino Acids; Animals; Autoantibodies; CD4-Positive T-Lymphocytes; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; Epitopes; Female; Immune Tolerance; Immunization; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mutant Proteins; Phenylalanine; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2011 |
Autophagy induction by tetrahydrobiopterin deficiency.
Topics: Alcohol Oxidoreductases; Animals; Autophagy; Biopterins; Child; Down-Regulation; Female; Humans; Infant; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Monomeric GTP-Binding Proteins; Multiprotein Complexes; Neuropeptides; NIH 3T3 Cells; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Proteins; Ras Homolog Enriched in Brain Protein; TOR Serine-Threonine Kinases; Tyrosine | 2011 |
Corticosteroids increase protein breakdown and loss in newly diagnosed pediatric Crohn disease.
Topics: Adolescent; Blood Glucose; Body Composition; Child; Crohn Disease; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Leucine; Phenylalanine; Prednisone; Proteins; Proteolysis; Tyrosine; Urea | 2011 |
Scallop phenylalanine hydroxylase implicates in immune response and can be induced by human TNF-α.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA, Complementary; Expressed Sequence Tags; Gene Expression Profiling; Humans; Molecular Sequence Data; Open Reading Frames; Pectinidae; Phenylalanine; Phenylalanine Hydroxylase; Protein Structure, Tertiary; Sequence Analysis, DNA; Tumor Necrosis Factor-alpha; Tyrosine; Vibrio | 2011 |
The production of intrinsically labeled milk and meat protein is feasible and provides functional tools for human nutrition research.
Topics: Adult; Animals; Carbon Isotopes; Cattle; Digestion; Female; Humans; Intestinal Absorption; Male; Meat; Milk; Milk Proteins; Muscle Proteins; Nutritional Sciences; Phenylalanine; Tyrosine | 2011 |
Two amino acid residues contribute to a cation-π binding interaction in the binding site of an insect GABA receptor.
Topics: Animals; Binding Sites; Cysteine; Female; gamma-Aminobutyric Acid; Hydrogen Bonding; Insect Proteins; Mutagenesis, Site-Directed; Oocytes; Phenylalanine; Protein Structure, Tertiary; Protein Subunits; Spodoptera; Tyrosine; Xenopus laevis | 2011 |
A digital microfluidic method for dried blood spot analysis.
Topics: Amino Acids; Automation; Butanols; Dried Blood Spot Testing; Methionine; Microfluidic Analytical Techniques; Phenylalanine; Tandem Mass Spectrometry; Tyrosine | 2011 |
Frequency Determination of α-1,3 Glucosyltransferase p.Y131H and p.F304S Polymorphisms in the Croatian Population Revealed Five Novel Single Nucleotide Polymorphisms in the hALG6 Gene.
Topics: Adult; Amino Acid Substitution; Base Sequence; Croatia; Female; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Glucosyltransferases; Humans; Male; Membrane Proteins; Middle Aged; Phenylalanine; Polymorphism, Single Nucleotide; Serine; Tryptophan; Tyrosine; Young Adult | 2012 |
Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.
Topics: Amino Acid Substitution; Blood Platelets; Cells, Cultured; Endothelial Cells; Factor VIII; Humans; Microtubules; Phenylalanine; Protein Multimerization; Transfection; Tyrosine; von Willebrand Factor; Weibel-Palade Bodies | 2011 |
[Amides of creatine: perspectives of neuroprotection].
Topics: Amides; Animals; Brain Ischemia; Creatine; Female; gamma-Aminobutyric Acid; Glycine; Hemodynamics; Image Processing, Computer-Assisted; Infarction, Middle Cerebral Artery; Injections, Intraperitoneal; Injections, Intravenous; Ischemic Attack, Transient; Male; Microscopy; Microtomy; Models, Animal; Neuroprotective Agents; Phenylalanine; Rats; Rats, Wistar; Tetrazolium Salts; Tyrosine | 2011 |
Tissue specific diurnal rhythms of metabolites and their regulation during herbivore attack in a native tobacco, Nicotiana attenuata.
Topics: Animals; Circadian Rhythm; Cyclopentanes; Disaccharides; Fatty Acids, Unsaturated; Genes, Plant; Glycosides; Herbivory; Larva; Manduca; Mechanical Phenomena; Nicotiana; Organ Specificity; Oxylipins; Phenylalanine; Plant Leaves; Plant Roots; Polyamines; RNA, Messenger; Tyrosine | 2011 |
Involvement of the global Crp regulator in cyclic AMP-dependent utilization of aromatic amino acids by Pseudomonas putida.
Topics: Amino Acids, Aromatic; Bacterial Proteins; Conditioning, Operant; Cyclic AMP; Cyclic AMP Receptor Protein; Gene Expression Regulation, Bacterial; Models, Molecular; Phenylalanine; Pseudomonas putida; Tyrosine | 2012 |
Tyrosine isomers mediate the classical phenomenon of concomitant tumor resistance.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Resistance; Extracellular Signal-Regulated MAP Kinases; Female; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; STAT3 Transcription Factor; Tyrosine | 2011 |
Adsorption and properties of aromatic amino acids on single-walled carbon nanotubes.
Topics: Adsorption; Amino Acids, Aromatic; Models, Molecular; Nanotubes, Carbon; Phenylalanine; Quantum Theory; Tryptophan; Tyrosine | 2012 |
Long-term outcome of living donor liver transplantation in a Thai boy with hereditary tyrosinemia type I: a case report.
Topics: Asian People; Diet Therapy; Heptanoates; Humans; Hydrolases; Infant; Liver Failure; Liver Transplantation; Living Donors; Male; Mutation; Phenylalanine; Thailand; Treatment Outcome; Tyrosine; Tyrosinemias | 2011 |
LC-MS/MS method for simultaneous determination on a dried blood spot of multiple analytes relevant for treatment monitoring in patients with tyrosinemia type I.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Biomarkers; Child; Child, Preschool; Chromatography, Liquid; Cyclohexanones; Diet, Protein-Restricted; Drug Monitoring; Enzyme Inhibitors; Heptanoates; Humans; Infant; Infant, Newborn; Kidney; Liver; Methionine; Nitrobenzoates; Phenylalanine; Tandem Mass Spectrometry; Tyrosine; Tyrosinemias | 2012 |
Identification of a Cryptococcus neoformans cytochrome P450 lanosterol 14α-demethylase (Erg11) residue critical for differential susceptibility between fluconazole/voriconazole and itraconazole/posaconazole.
Topics: 14-alpha Demethylase Inhibitors; Animals; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Drug Resistance, Fungal; Female; Fluconazole; Fungal Proteins; Genotype; Humans; Itraconazole; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mutation, Missense; Phenylalanine; Pyrimidines; Sterol 14-Demethylase; Survival Rate; Triazoles; Tyrosine; Voriconazole | 2012 |
Diurnal variation of phenylalanine concentrations in tyrosinaemia type 1: should we be concerned?
Topics: Child; Child, Preschool; Circadian Rhythm; Dietary Proteins; Female; Humans; Male; Phenylalanine; Practice Guidelines as Topic; Retrospective Studies; Tyrosine; Tyrosinemias | 2012 |
Mutation of Phe413 to Tyr in catalase KatE from Escherichia coli leads to side chain damage and main chain cleavage.
Topics: Arginine; Catalase; Crystallography, X-Ray; Escherichia coli; Genetic Variation; Heme; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Models, Molecular; Molecular Conformation; Mutation; Oxygen; Phenylalanine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2012 |
Interferon-alpha therapy in patients with hepatitis C virus infection increases plasma phenylalanine and the phenylalanine to tyrosine ratio.
Topics: Adult; Biosynthetic Pathways; Chromatography, High Pressure Liquid; Female; Hepacivirus; Hepatitis, Chronic; Humans; Immunotherapy; Interferon-alpha; Male; Middle Aged; Mood Disorders; Phenylalanine; Polyethylene Glycols; Recombinant Proteins; Ribavirin; Treatment Outcome; Tyrosine; Viral Load | 2012 |
meta-Tyrosine in Festuca rubra ssp. commutata (Chewings fescue) is synthesized by hydroxylation of phenylalanine.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Festuca; Hydroxylation; Molecular Structure; Phenylalanine; Plant Roots; Tyrosine | 2012 |
Anabolic signaling and protein deposition are enhanced by intermittent compared with continuous feeding in skeletal muscle of neonates.
Topics: Algorithms; Amino Acids; Animals; Animals, Newborn; Blood Glucose; Blotting, Western; Diet; Eating; Eukaryotic Initiation Factor-4E; Fasting; Female; Hindlimb; Hydroxylation; Insulin; Male; Metabolism; Muscle Proteins; Phenylalanine; Signal Transduction; Swine; Time Factors; Tyrosine | 2012 |
Dopamine and food reward: effects of acute tyrosine/phenylalanine depletion on appetite.
Topics: Adult; Analysis of Variance; Appetite Regulation; Cross-Over Studies; Dopamine; Double-Blind Method; Eating; Humans; Hunger; Male; Motivation; Phenylalanine; Reference Values; Reward; Tyrosine | 2012 |
Understanding product specificity of protein lysine methyltransferases from QM/MM molecular dynamics and free energy simulations: the effects of mutation on SET7/9 beyond the Tyr/Phe switch.
Topics: Computer Simulation; Histone-Lysine N-Methyltransferase; Humans; Molecular Dynamics Simulation; Mutation, Missense; Phenylalanine; Substrate Specificity; Thermodynamics; Tyrosine | 2012 |
[Determination of amino acid contents in cottonseeds using near infrared reflectance spectroscopy].
Topics: Alanine; Amino Acids; Arginine; Asparagine; Calibration; Cottonseed Oil; Cystine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Phenylalanine; Proline; Serine; Spectroscopy, Near-Infrared; Threonine; Tyrosine; Valine | 2011 |
Tyrosine phosphorylation of estradiol receptor by Src regulates its hormone-dependent nuclear export and cell cycle progression in breast cancer cells.
Topics: Active Transport, Cell Nucleus; Animals; Breast Neoplasms; Cell Cycle Checkpoints; Cell Growth Processes; Cell Line; Cell Line, Tumor; Cell Nucleus; Chlorocebus aethiops; COS Cells; Cyclin D1; Cytoplasm; Estradiol; Estrogen Receptor alpha; Exportin 1 Protein; Female; Forkhead Transcription Factors; Humans; Karyopherins; MCF-7 Cells; Mice; Mutation; NIH 3T3 Cells; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; ran GTP-Binding Protein; Receptors, Cytoplasmic and Nuclear; S Phase; src-Family Kinases; Transcription, Genetic; Tyrosine | 2012 |
Quantification of phenylalanine hydroxylase activity by isotope-dilution liquid chromatography-electrospray ionization tandem mass spectrometry.
Topics: Animals; Biopterins; Brain; Cells, Cultured; Chlorocebus aethiops; Chromatography, Liquid; COS Cells; Humans; Isotope Labeling; Kidney; Liver; Mice; Mutation; Phenotype; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tyrosine | 2012 |
Metabolic differences underlying two distinct rat urinary phenotypes, a suggested role for gut microbial metabolism of phenylalanine and a possible connection to autism.
Topics: Animals; Autistic Disorder; Bacterial Proteins; Biomarkers; Chlorogenic Acid; Clostridium; Disease Models, Animal; Fungal Proteins; Glycine; Hippurates; Humans; Intestines; Phenylalanine; Phenylalanine Ammonia-Lyase; Rats; Stereoisomerism; Systems Biology; Tryptophan; Tyrosine; Yeasts | 2012 |
Effect of water coordination on competition between π and non-π cation binding sites in aromatic amino acids: L-phenylalanine, L-tyrosine, and L-tryptophan Li+, Na +, and K+ complexes.
Topics: Binding Sites; Cations; Cations, Monovalent; Metals, Alkali; Molecular Structure; Phenylalanine; Quantum Theory; Tryptophan; Tyrosine; Water | 2012 |
Protein ingestion before sleep improves postexercise overnight recovery.
Topics: Amino Acids; Dietary Proteins; Digestion; Exercise; Humans; Male; Muscle, Skeletal; Phenylalanine; Sleep; Tyrosine; Young Adult | 2012 |
Reversal of metabolic and neurological symptoms of phenylketonuric mice treated with a PAH containing helper-dependent adenoviral vector.
Topics: Adenoviridae; Animals; Disease Models, Animal; Electrophysiology; Genetic Therapy; Genetic Vectors; Humans; Learning Disabilities; Mice; N-Methylaspartate; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pigmentation; Tyrosine | 2012 |
Alterations in amino acid concentrations in the plasma and muscle in human subjects during 24 h of simulated adventure racing.
Topics: Adult; Amino Acids; Exercise; Glycogen; Humans; Male; Muscle, Skeletal; Phenylalanine; Running; Tyrosine | 2012 |
Biaryl-bridged macrocyclic peptides: conformational constraint via carbogenic fusion of natural amino acid side chains.
Topics: Amino Acids; Molecular Structure; Peptides; Peptides, Cyclic; Phenylalanine; Solutions; Stereoisomerism; Tyrosine | 2012 |
Psychiatric side effects and fluctuations in serotonergic parameters in the treatment of chronic hepatitis C infection.
Topics: Adult; Antiviral Agents; Chromatography, High Pressure Liquid; Female; Hepatitis C, Chronic; Humans; Interferon-alpha; Male; Middle Aged; Mood Disorders; Neopterin; Phenylalanine; Polyethylene Glycols; Prolactin; Psychometrics; Recombinant Proteins; Serotonin; Statistics, Nonparametric; Time Factors; Tyrosine | 2012 |
[Preparation of chiral monolithic column with covalently bonded cellulose and their application to rapid enantioseparation].
Topics: Acrylamides; Benzoates; Capillary Electrochromatography; Cellulose; Phenylalanine; Propranolol; Stereoisomerism; Succinimides; Tyrosine | 2011 |
Identification of the key residues determining the product specificity of isomerohydrolase.
Topics: Amino Acid Sequence; Animals; Catalytic Domain; Chickens; cis-trans-Isomerases; Leucine; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Pigment Epithelium of Eye; Substrate Specificity; Tyrosine; Vitamin A; Zebrafish | 2012 |
Engineering tyrosine-based electron flow pathways in proteins: the case of aplysia myoglobin.
Topics: Animals; Aplysia; Lipid Metabolism; Models, Molecular; Mutation; Myoglobin; Oxidation-Reduction; Phenylalanine; Protein Engineering; Tyrosine | 2012 |
Conformational mapping and energetics of saccharide-aromatic residue interactions: implications for the discrimination of anomers and epimers and in protein engineering.
Topics: Binding Sites; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Monosaccharides; Phenylalanine; Protein Engineering; Quantum Theory; Stereoisomerism; Thermodynamics; Tyrosine | 2012 |
Perturbation of the redox site structure of cytochrome c variants upon tyrosine nitration.
Topics: Cytochromes c; Fatty Acids; Heme; Humans; Iron; Kinetics; Lysine; Methionine; Mutation; Nitro Compounds; Oxidation-Reduction; Phenylalanine; Protein Stability; Protein Structure, Quaternary; Recombinant Proteins; Silver Compounds; Static Electricity; Sulfhydryl Compounds; Tyrosine; Water | 2012 |
Circulating metabolite predictors of glycemia in middle-aged men and women.
Topics: Alanine; Amino Acids, Branched-Chain; Blood Glucose; Fasting; Female; Humans; Male; Middle Aged; Orosomucoid; Phenylalanine; Pyruvic Acid; Tyrosine | 2012 |
Depressive symptoms in adolescents with early and continuously treated phenylketonuria: associations with phenylalanine and tyrosine levels.
Topics: Adolescent; Depression; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 2012 |
Functional differences between ATP-gated human and rat P2X3 receptors are caused by critical residues of the intracellular C-terminal domain.
Topics: Adenosine Triphosphate; Animals; Biophysical Phenomena; Biotinylation; CSK Tyrosine-Protein Kinase; Electric Stimulation; Gene Expression Regulation; Green Fluorescent Proteins; HEK293 Cells; Humans; Immunoprecipitation; Ion Channel Gating; Membrane Potentials; Mutagenesis; Mutation; Patch-Clamp Techniques; Phenylalanine; Protein-Tyrosine Kinases; Purinergic P2X Receptor Agonists; Rats; Receptors, Purinergic P2X3; RNA Interference; RNA, Small Interfering; Species Specificity; src-Family Kinases; Transfection; Tyrosine | 2012 |
On the autofluorescence of fingermarks.
Topics: beta Carotene; Bilirubin; Chlorophyll; Chromatography, Thin Layer; Dermatoglyphics; Flavin-Adenine Dinucleotide; Fluorescence; Humans; Kynurenine; Light; Phenylalanine; Pheophytins; Protoporphyrins; Riboflavin; Sebum; Spectrometry, Fluorescence; Sweat; Thiamine; Tryptophan; Tyrosine; Ultraviolet Rays; Vitamin B 6; Xanthurenates | 2012 |
Non-synonymous single nucleotide polymorphisms in genes for immunoregulatory galectins: association of galectin-8 (F19Y) occurrence with autoimmune diseases in a Caucasian population.
Topics: Adolescent; Adult; Aged; Amino Acid Substitution; Autoimmune Diseases; Case-Control Studies; Female; Galectins; Genetic Association Studies; Genetics, Population; Humans; Immunologic Factors; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polymorphism, Single Nucleotide; Tyrosine; White People; Young Adult | 2012 |
Formation of self-aggregated structures of different types in water of chiral polymerizable amphiphiles from L-tyrosine and L-phenylalanine.
Topics: Diphenylhexatriene; Emulsions; Esters; Hydrophobic and Hydrophilic Interactions; Maleates; Models, Molecular; Molecular Conformation; Phenylalanine; Polymerization; Pyrenes; Spectrometry, Fluorescence; Stereoisomerism; Surface Tension; Tyrosine; Viscosity; Water | 2012 |
High performance controlled reactors from micellar assemblies of aromatic amino acid amphiphiles for nanoparticle synthesis.
Topics: Emulsions; Hydrophobic and Hydrophilic Interactions; Kinetics; Laurates; Micelles; Microscopy, Electron, Transmission; Molecular Weight; Nanoparticles; Particle Size; Phenylalanine; Polymerization; Sodium Dodecyl Sulfate; Solubility; Styrene; Surface-Active Agents; Tyrosine; Water | 2012 |
Aromatic residues in the substrate cleft of RPE65 protein govern retinol isomerization and modulate its progression.
Topics: Amino Acid Substitution; Animals; Binding Sites; cis-trans-Isomerases; Crystallography, X-Ray; Mice; Mutation, Missense; Phenylalanine; Protein Binding; Tyrosine; Vitamin A | 2012 |
¹³C relaxation experiments for aromatic side chains employing longitudinal- and transverse-relaxation optimized NMR spectroscopy.
Topics: Binding Sites; Carbon Isotopes; Histamine; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Conformation; Protein Structure, Tertiary; Proteins; Tyrosine | 2012 |
Aβ-40 Y10F increases βfibrils formation but attenuates the neurotoxicity of amyloid-β peptide.
Topics: Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Animals; Cells, Cultured; Humans; Hydrogen Peroxide; Neurons; Peptide Fragments; Phenylalanine; Protein Aggregation, Pathological; Protein Folding; Protein Structure, Secondary; Rats, Sprague-Dawley; Tyrosine | 2012 |
The use of UV-Vis absorption spectroscopy for studies of natively disordered proteins.
Topics: Algorithms; Phenylalanine; Protein Structure, Secondary; Protein Structure, Tertiary; Proteins; Quantum Theory; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 2012 |
A study of aromatic hydrogen bonds of peptides with aromatic amino acid side-chains.
Topics: Amino Acids, Aromatic; Biochemistry; Computer Simulation; Crystallography, X-Ray; Histidine; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Peptides; Phenylalanine; Probability; Static Electricity; Tyrosine | 2004 |
Bioinspired bioadhesive polymers: dopa-modified poly(acrylic acid) derivatives.
Topics: Acrylic Resins; Adhesiveness; Animals; Biomimetic Materials; Calorimetry, Differential Scanning; Dihydroxyphenylalanine; Gastropoda; Intestines; Magnetic Resonance Spectroscopy; Male; Materials Testing; Methylmethacrylates; Phenylalanine; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tissue Adhesives; Tissue Culture Techniques; Tyrosine | 2012 |
Conductance properties of the inwardly rectifying channel, Kir3.2: molecular and Brownian dynamics study.
Topics: Animals; Bee Venoms; Biophysics; Electric Conductivity; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamic Acid; Ion Channel Gating; Ions; Kinetics; Lysine; Magnesium; Mice; Models, Molecular; Models, Statistical; Molecular Conformation; Mutation; Peptides; Phenylalanine; Protein Binding; Tyrosine | 2013 |
AhpC is required for optimal production of enterobactin by Escherichia coli.
Topics: Chorismic Acid; Culture Media; Enterobactin; Escherichia coli; Escherichia coli Proteins; Gene Deletion; Hydroxybenzoates; Iron; para-Aminobenzoates; Peroxiredoxins; Phenylalanine; Shikimic Acid; Tryptophan; Tyrosine | 2012 |
Transfer RNA gene numbers may not be completely responsible for the codon usage bias in asparagine, isoleucine, phenylalanine, and tyrosine in the high expression genes in bacteria.
Topics: Asparagine; Bacterial Proteins; Codon; DNA-Directed RNA Polymerases; Gene Dosage; Genes, Bacterial; Genome, Bacterial; Isoleucine; Models, Genetic; Phenylalanine; Protein Biosynthesis; RNA, Bacterial; RNA, Transfer; Tyrosine | 2012 |
Long-term treatment with tetrahydrobiopterin in phenylketonuria: treatment strategies and prediction of long-term responders.
Topics: Adolescent; Biomarkers, Pharmacological; Biopterins; Child; Child, Preschool; Disease Management; Drug Administration Schedule; Female; Humans; Long-Term Care; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Prognosis; Tyrosine | 2012 |
Discovery of novel glitazones incorporated with phenylalanine and tyrosine: synthesis, antidiabetic activity and structure-activity relationships.
Topics: Animals; Blood Glucose; Drug Evaluation, Preclinical; Hyperlipidemias; Hypoglycemic Agents; Liver; Phenylalanine; Rats; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones; Triglycerides; Tyrosine | 2012 |
A green fluorescent protein containing a QFG tri-peptide chromophore: optical properties and X-ray crystal structure.
Topics: Crystallography, X-Ray; Green Fluorescent Proteins; Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Mutagenesis; Oligopeptides; Phenylalanine; Protein Conformation; Spectrometry, Fluorescence; Tyrosine | 2012 |
Tyrosine metabolism during interferon-alpha administration: association with fatigue and CSF dopamine concentrations.
Topics: Adult; Antiviral Agents; Dopamine; Fatigue; Female; Hepatitis C; Humans; Interferon-alpha; Interleukin-6; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Tyrosine | 2013 |
Identification of sites in apolipoprotein A-I susceptible to chymase and carboxypeptidase A digestion.
Topics: Aorta, Thoracic; Apolipoprotein A-I; Biomarkers; Carboxypeptidases A; Catalytic Domain; Chymases; Electrophoresis, Polyacrylamide Gel; Humans; Immunohistochemistry; Lipoproteins, HDL3; Phenylalanine; Plaque, Atherosclerotic; Proteolysis; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine | 2012 |
Eliminating tyrosine sequence variants in CHO cell lines producing recombinant monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; CHO Cells; Cricetinae; Cricetulus; Histidine; Phenylalanine; Recombinant Proteins; Tyrosine | 2013 |
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
Topics: Adult; Amino Acids; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Phenylalanine; Tyrosine; Valine; Young Adult | 2013 |
Behavioral and intellectual functioning in patients with tyrosinemia type I.
Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Child; Cognition Disorders; Female; Humans; Intelligence Tests; Male; Mental Disorders; Phenylalanine; Problem Solving; Tyrosine; Tyrosinemias; Wechsler Scales | 2012 |
The role of amino acids in spina bifida.
Topics: Adult; Alanine; Amino Acids; Amniocentesis; Amniotic Fluid; Cystathionine; Cysteine; Female; Gestational Age; Humans; Phenylalanine; Pregnancy; Pregnancy Trimester, Second; Spinal Dysraphism; Tryptophan; Tyrosine; Ultrasonography, Prenatal | 2012 |
Dopamine precursor depletion impairs timing in healthy volunteers by attenuating activity in putamen and supplementary motor area.
Topics: Adolescent; Adult; Amino Acids; Cognition; Color Perception; Data Interpretation, Statistical; Discrimination, Psychological; Dopamine; Female; Hemodynamics; Humans; Magnetic Resonance Imaging; Male; Memory, Short-Term; Middle Aged; Motor Cortex; Phenylalanine; Photic Stimulation; Psychomotor Performance; Putamen; Time Perception; Tyrosine; Young Adult | 2012 |
Phosphorylation at tyrosine 114 of Proliferating Cell Nuclear Antigen (PCNA) is required for adipogenesis in response to high fat diet.
Topics: Adipogenesis; Adipose Tissue; Alleles; Amino Acid Sequence; Amino Acid Substitution; Animals; Body Weight; Cell Proliferation; Diet, High-Fat; DNA Replication; Female; Gene Knock-In Techniques; Mice; Mice, Knockout; Models, Genetic; Molecular Sequence Data; Phenylalanine; Phosphorylation; Proliferating Cell Nuclear Antigen; Tyrosine | 2013 |
The aggregation behavior of native collagen in dilute solution studied by intrinsic fluorescence and external probing.
Topics: Anilino Naphthalenesulfonates; Animals; Cattle; Collagen Type I; Fluorescence Resonance Energy Transfer; Guanidine; Phenylalanine; Protein Unfolding; Solutions; Tyrosine | 2013 |
Chiral bio-nanocomposites based on thermally stable poly(amide-imide) having phenylalanine linkages and reactive organoclay containing tyrosine amino acid.
Topics: Amides; Imides; Molecular Structure; Nanocomposites; Phenylalanine; Polymerization; Polymers; Spectroscopy, Fourier Transform Infrared; Tyrosine | 2013 |
[Analysis of surface enhanced Raman scattering spectra of oxyhemoglobin for liver cancer with combined multivariate statistics].
Topics: Algorithms; Asparagine; Discriminant Analysis; Humans; Liver Neoplasms; Oxyhemoglobins; Phenylalanine; Principal Component Analysis; Silver; Spectrum Analysis, Raman; Tyrosine | 2012 |
Role of aromatic interactions in amyloid formation by islet amyloid polypeptide.
Topics: Amino Acid Sequence; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Phenylalanine; Propanols; Tyrosine | 2013 |
Enantioseparations by thin-layer chromatography.
Topics: Animals; beta-Cyclodextrins; Cattle; Cellulose; Chromatography, Thin Layer; Molecular Imprinting; Phenylalanine; Polymers; Serum Albumin, Bovine; Thiohydantoins; Tyrosine; Warfarin | 2013 |
Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Blotting, Western; COS Cells; Flow Cytometry; Glutamic Acid; HEK293 Cells; Humans; Interleukin-2; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Lectins, C-Type; Lymphocyte Activation; Mutation; Oncogene Proteins, Fusion; Phenylalanine; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; T-Lymphocytes; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 2013 |
Kinetic mechanism of phenylalanine hydroxylase: intrinsic binding and rate constants from single-turnover experiments.
Topics: Animals; Binding Sites; Catalysis; Hydroxylation; Kinetics; Mutation; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Pterins; Rats; Substrate Specificity; Tyrosine | 2013 |
Proteome-wide analysis of nonsynonymous single-nucleotide variations in active sites of human proteins.
Topics: Abnormalities, Multiple; Amino Acid Substitution; Arginine; Aspartic Acid; Carbohydrate Metabolism; Catalytic Domain; Cluster Analysis; Enzyme Activation; Genetic Variation; Genome, Human; Glycogen Storage Disease; Hearing Loss; Histidine; Humans; Lacrimal Apparatus Diseases; Metabolomics; Molecular Sequence Annotation; Phenylalanine; Polymorphism, Single Nucleotide; Proteome; Proteomics; Structure-Activity Relationship; Syndactyly; Tooth Abnormalities; Tyrosine | 2013 |
The effect of acute tyrosine phenylalanine depletion on emotion-based decision-making in healthy adults.
Topics: Adult; Decision Making; Emotions; Female; Humans; Male; Phenylalanine; Reference Values; Tyrosine | 2013 |
Pitfalls in phenylalanine loading test in the diagnosis of dopa-responsive dystonia.
Topics: Administration, Oral; Adult; Biopterins; Diagnosis, Differential; Dystonia; Dystonic Disorders; Female; Humans; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Psychomotor Disorders; Tyrosine | 2013 |
Fluorogenic tagging methodology applied to characterize oxidized tyrosine and phenylalanine in an immunoglobulin monoclonal antibody.
Topics: Ascorbic Acid; Benzoxazoles; Copper; Immunoglobulin G; Oxidation-Reduction; Phenylalanine; Spectrometry, Fluorescence; Tyrosine | 2013 |
Aromatic amino acids in high selectivity bismuth(III) recognition.
Topics: Bismuth; Phenylalanine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2013 |
[Asymmetric synthesis of aromatic L-amino acids catalyzed by transaminase].
Topics: Amino Acids, Aromatic; Catalysis; Escherichia coli; Phenylalanine; Protein Engineering; Saccharomyces cerevisiae; Stereoisomerism; Transaminases; Tyrosine | 2012 |
Self-assembling multidomain peptide fibers with aromatic cores.
Topics: Amino Acid Sequence; Amino Acid Substitution; Biocompatible Materials; Elasticity; Hydrogels; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Microscopy, Electron, Scanning; Molecular Dynamics Simulation; Molecular Sequence Data; Nanofibers; Peptides; Phenylalanine; Protein Structure, Tertiary; Rheology; Tissue Scaffolds; Tryptophan; Tyrosine | 2013 |
Residues at the cytoplasmic end of transmembrane helix 2 determine the signal output of the TarEc chemoreceptor.
Topics: Aspartic Acid; Chemotaxis; Cytoplasm; Escherichia coli Proteins; Glycine; Methylation; Mutation; Phenylalanine; Protein Structure, Tertiary; Receptors, Cell Surface; Signal Transduction; Tyrosine | 2013 |
Metal cation dependence of interactions with amino acids: bond energies of Rb+ and Cs+ to Met, Phe, Tyr, and Trp.
Topics: Cations; Cesium; Coordination Complexes; Methionine; Models, Molecular; Phenylalanine; Quantum Theory; Rubidium; Tandem Mass Spectrometry; Thermodynamics; Tryptophan; Tyrosine | 2013 |
Crystallographic structure determination of B10 mutants of Vitreoscilla hemoglobin: role of Tyr29 (B10) in the structure of the ligand-binding site.
Topics: Alanine; Bacterial Proteins; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Escherichia coli; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Oxygen; Phenylalanine; Proline; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Truncated Hemoglobins; Tyrosine; Vitreoscilla | 2013 |
π-π Interactions in structural stability: role in RNA binding proteins.
Topics: Databases, Protein; Electrons; Phenylalanine; Protein Structure, Secondary; Quantum Theory; RNA-Binding Proteins; Solvents; Tyrosine | 2013 |
Computational study on the attack of ·OH radicals on aromatic amino acids.
Topics: Amino Acids, Aromatic; Hydroxyl Radical; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenylalanine; Proteins; Stereoisomerism; Thermodynamics; Tryptophan; Tyrosine | 2013 |
Amino acids as co-amorphous stabilizers for poorly water soluble drugs--Part 1: preparation, stability and dissolution enhancement.
Topics: Amino Acids; Arginine; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Design; Phenylalanine; Polymers; Solubility; Technology, Pharmaceutical; Temperature; Tryptophan; Tyrosine; X-Ray Diffraction | 2013 |
Immune activation in patients with Alzheimer's disease is associated with high serum phenylalanine concentrations.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Neuropsychological Tests; Phenylalanine; Psychiatric Status Rating Scales; Single-Blind Method; Statistics, Nonparametric; Tyrosine | 2013 |
pH-responsive aggregation states of chiral polymerizable amphiphiles from L-tyrosine and L-phenyl alanine in water.
Topics: Hydrogen-Ion Concentration; Models, Molecular; Molecular Structure; Particle Size; Phenylalanine; Polymerization; Surface Properties; Surface-Active Agents; Tyrosine; Water | 2013 |
Adaptation of phenylalanine and tyrosine catabolic pathway to hibernation in bats.
Topics: Acetoacetates; Adaptation, Physiological; Animals; Blotting, Western; Chiroptera; Electrophoresis, Gel, Two-Dimensional; Hibernation; Liver; Metabolic Networks and Pathways; Models, Molecular; Phenylalanine; Proteome; Selection, Genetic; Sequence Analysis, Protein; Transcription Factors; Tyrosine | 2013 |
A new member of the 4-methylideneimidazole-5-one-containing aminomutase family from the enediyne kedarcidin biosynthetic pathway.
Topics: Ammonia; Antineoplastic Agents; Computational Biology; Cycloparaffins; Enediynes; Imidazoles; Intramolecular Transferases; Kinetics; Lyases; Molecular Sequence Data; Naphthalenes; Phenylalanine; Streptomyces; Substrate Specificity; Tyrosine | 2013 |
Monitoring conformational changes in peroxisome proliferator-activated receptor α by a genetically encoded photoamino acid, cross-linking, and mass spectrometry.
Topics: Benzophenones; Binding Sites; Butyrates; Cross-Linking Reagents; Genetic Variation; Ligands; Models, Molecular; Oxazoles; Phenylalanine; Phenylurea Compounds; PPAR alpha; Protein Binding; Protein Conformation; Protein Multimerization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine; Ultraviolet Rays | 2013 |
Diurnal variation of phenylalanine and tyrosine concentrations in adult patients with phenylketonuria: subcutaneous microdialysis is no adequate tool for the determination of amino acid concentrations.
Topics: Administration, Oral; Adult; Circadian Rhythm; Diet; Female; Humans; Male; Meals; Microdialysis; Motor Activity; Phenylalanine; Phenylketonurias; Subcutaneous Tissue; Tyrosine; Young Adult | 2013 |
Amino acid analysis of dried blood spots for diagnosis of phenylketonuria using capillary electrophoresis-mass spectrometry equipped with a sheathless electrospray ionization interface.
Topics: Amino Acids; Dried Blood Spot Testing; Electrophoresis, Capillary; Humans; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylketonurias; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2013 |
Simultaneous determination of phenylalanine and tyrosine in peripheral capillary blood by HPLC with ultraviolet detection.
Topics: Anticoagulants; Calibration; Child; Child, Preschool; Chromatography, High Pressure Liquid; Female; Health; Humans; Infant; Infant, Newborn; Male; Phenylalanine; Reference Standards; Temperature; Time Factors; Tyrosine; Ultraviolet Rays | 2013 |
Reliable analysis of phenylalanine and tyrosine in a minimal volume of blood.
Topics: Dried Blood Spot Testing; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tandem Mass Spectrometry; Tyrosine | 2013 |
Dopamine and light: dissecting effects on mood and motivational states in women with subsyndromal seasonal affective disorder.
Topics: Adult; Affect; Dopamine; Female; Humans; Light; Motivation; Phenylalanine; Psychomotor Performance; Reward; Seasonal Affective Disorder; Tyrosine | 2013 |
Neisseria meningitidis expresses a single 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase that is inhibited primarily by phenylalanine.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Allosteric Regulation; Amino Acid Substitution; Amino Acids, Aromatic; Binding Sites; Crystallography, X-Ray; Enzyme Stability; Feedback, Physiological; Neisseria meningitidis; Phenylalanine; Protein Multimerization; Protein Structure, Tertiary; Scattering, Small Angle; Tryptophan; Tyrosine; X-Ray Diffraction | 2013 |
Carbohydrate-aromatic interactions: vibrational spectroscopy and structural assignment of isolated monosaccharide complexes with p-hydroxy toluene and N-acetyl l-tyrosine methylamide.
Topics: Amides; Hydrogen Bonding; Monosaccharides; Phenylalanine; Quantum Theory; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Toluene; Tyrosine | 2013 |
Identification of residues essential for the activity and substrate affinity of L-carnitine dehydrogenase.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Carnitine; Catalytic Domain; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Rhizobium; Substrate Specificity; Tyrosine; Xanthomonas | 2013 |
Caffeic acid production enhancement by engineering a phenylalanine over-producing Escherichia coli strain.
Topics: Caffeic Acids; Escherichia coli; Metabolic Engineering; Mixed Function Oxygenases; Phenylalanine; Tyrosine | 2013 |
Substantial Differences between Organ and Muscle Specific Tracer Incorporation Rates in a Lactating Dairy Cow.
Topics: Animals; Carbon Isotopes; Cattle; Female; Kidney; Kinetics; Lactation; Liver; Mammary Glands, Animal; Meat; Milk; Muscle, Skeletal; Phenylalanine; Tyrosine | 2013 |
Pregnancy in an NTBC-treated patient with hereditary tyrosinemia type I.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Combined Modality Therapy; Contraindications; Cyclohexanones; Enzyme Inhibitors; Female; Humans; Nitrobenzoates; Phenylalanine; Pregnancy; Pregnancy Complications; Term Birth; Tyrosine; Tyrosinemias | 2015 |
[Laser photolysis study on photo-oxidation reactions of aromatic amino acids with triplet 2-methylanthraquinone].
Topics: Amino Acids, Aromatic; Anthraquinones; Electron Transport; Lasers; Oxidation-Reduction; Phenylalanine; Photolysis; Tryptophan; Tyrosine | 2013 |
Slow aromatic ring flips detected despite near-degenerate NMR frequencies of the exchanging nuclei.
Topics: Animals; Aprotinin; Carbon Isotopes; Cattle; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Pancreas; Phenylalanine; Tyrosine | 2013 |
Allosteric inhibitor specificity of Thermotoga maritima 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Allosteric Regulation; Amino Acid Substitution; Bacterial Proteins; Enzyme Assays; Kinetics; Molecular Docking Simulation; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Structure-Activity Relationship; Thermotoga maritima; Tyrosine | 2013 |
Evaluation of an adsorbent based on agricultural waste (corn cobs) for removal of tyrosine and phenylalanine from aqueous solutions.
Topics: Adsorption; Agriculture; Humans; Industrial Waste; Phenylalanine; Protein Hydrolysates; Solutions; Tyrosine; Water; Zea mays | 2013 |
Possible chemical initiators of cognitive dysfunction in phenylketonuria, Parkinson's disease and Alzheimer's disease.
Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methionine; Models, Biological; Molecular Structure; Oxidative Stress; Parkinson Disease; Phenylalanine; Phenylketonurias; Tyrosine | 2013 |
Identification and analysis of the constituents in an aqueous extract of Tricholoma matsutake by HPLC coupled with diode array detection/electrospray ionization mass spectrometry.
Topics: Adenine; Adenosine; Chromatography, High Pressure Liquid; Cytidine; Deoxyadenosines; Guanosine; Inosine; Phenylalanine; Riboflavin; Spectrometry, Mass, Electrospray Ionization; Thionucleosides; Tricholoma; Tryptophan; Tyrosine; Uridine; Water | 2013 |
An analytical workflow for the molecular dissection of irreversibly modified fluorescent proteins.
Topics: Amino Acid Sequence; Chromatography, Reverse-Phase; Green Fluorescent Proteins; Mass Spectrometry; Methionine; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Phenylalanine; Protein Interaction Domains and Motifs; Pulse Radiolysis; Reactive Oxygen Species; Tyrosine | 2013 |
Optimization of an HPLC method for phenylalanine and tyrosine quantization in dried blood spot.
Topics: Adolescent; Chromatography, High Pressure Liquid; Dried Blood Spot Testing; Humans; Phenylalanine; Phenylketonurias; Reproducibility of Results; Sensitivity and Specificity; Tyrosine; Young Adult | 2013 |
Dietary manipulation of serotonergic and dopaminergic function in C57BL/6J mice with amino acid depletion mixtures.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acids; Animals; Brain; Chromatography, High Pressure Liquid; Dopamine; Food, Formulated; Homovanillic Acid; Male; Mice; Mice, Inbred C57BL; Phenylalanine; Serotonin; Statistics, Nonparametric; Tryptophan; Tyrosine | 2014 |
The relationship between consumption of tyrosine and phenylalanine as precursors of catecholamine at breakfast and the circadian typology and mental health in Japanese infants aged 2 to 5 years.
Topics: Analysis of Variance; Anger; Breakfast; Child, Preschool; Circadian Rhythm; Diet; Humans; Japan; Phenylalanine; Surveys and Questionnaires; Tyrosine | 2013 |
Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives.
Topics: Dimethylallyltranstransferase; Escherichia coli; Fungal Proteins; Gene Expression; Hemiterpenes; Kinetics; Organophosphorus Compounds; Phenylalanine; Piperazines; Prenylation; Recombinant Proteins; Saccharomycetales; Substrate Specificity; Sulfhydryl Compounds; Tryptophan; Tyrosine | 2013 |
[Study of interaction of umbelliferone with three aromatic amino acids by fluorescence spectroscopy].
Topics: Amino Acids, Aromatic; Binding Sites; Computer Simulation; Phenylalanine; Protein Interaction Domains and Motifs; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Umbelliferones | 2013 |
Functional analyses of the C-terminal half of the Saccharomyces cerevisiae Rad52 protein.
Topics: Amino Acid Sequence; DNA; DNA Repair; Homologous Recombination; Molecular Sequence Data; Mutation; Phenylalanine; Protein Multimerization; Rad51 Recombinase; Rad52 DNA Repair and Recombination Protein; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Tyrosine | 2014 |
Examination of tyrosine/adenine stacking interactions in protein complexes.
Topics: Adenine; Cresols; Crystallins; Databases, Protein; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Phenylalanine; Thermodynamics; Tyrosine | 2013 |
Phosphorylation of cystic fibrosis transmembrane conductance regulator (CFTR) serine-511 by the combined action of tyrosine kinases and CK2: the implication of tyrosine-512 and phenylalanine-508.
Topics: Casein Kinase II; Cystic Fibrosis Transmembrane Conductance Regulator; Humans; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; Serine; Tyrosine | 2013 |
Simultaneous measurement of phenylalanine and tyrosine by high performance liquid chromatography (HPLC) with fluorescence detection.
Topics: Calibration; Chromatography, High Pressure Liquid; Fluorescence; Humans; Limit of Detection; Phenylalanine; Tyrosine | 2013 |
Man made disease: clinical manifestations of low phenylalanine levels in an inadequately treated phenylketonuria patient and mouse study.
Topics: Alopecia; Animals; Body Weight; Corneal Perforation; Diarrhea, Infantile; Disease Models, Animal; Failure to Thrive; Female; Humans; Infant; Infant Formula; Male; Mice; Phenylalanine; Phenylketonurias; Random Allocation; Tyrosine; Vitamin A Deficiency | 2013 |
Dopamine and pain sensitivity: neither sulpiride nor acute phenylalanine and tyrosine depletion have effects on thermal pain sensations in healthy volunteers.
Topics: Adolescent; Adult; Affect; Anxiety; Dopamine; Dopamine D2 Receptor Antagonists; Female; Healthy Volunteers; Humans; Male; Pain; Pain Perception; Pain Threshold; Phenylalanine; Presynaptic Terminals; Receptors, Dopamine D2; Sulpiride; Thermosensing; Tyrosine; Young Adult | 2013 |
Site-saturation mutagenesis of central tyrosine 195 leading to diverse product specificities of an α-cyclodextrin glycosyltransferase from Paenibacillus sp. 602-1.
Topics: Bacterial Proteins; Catalytic Domain; Cyclization; Cyclodextrins; Enzyme Stability; Escherichia coli; Glucosyltransferases; Models, Molecular; Mutagenesis, Site-Directed; Paenibacillus; Phenylalanine; Starch; Substrate Specificity; Temperature; Tyrosine | 2014 |
Discovery of novel anti-HIV-1 agents based on a broadly neutralizing antibody against the envelope gp120 V3 loop: a computational study.
Topics: Anti-HIV Agents; Antibodies, Neutralizing; Computational Biology; Crystallography, X-Ray; Drug Discovery; HIV Envelope Protein gp120; Humans; Immunoglobulin Fab Fragments; Molecular Docking Simulation; Molecular Dynamics Simulation; Phenylalanine; Tyrosine | 2014 |
Comparison of fullerene and large argon clusters for the molecular depth profiling of amino acid multilayers.
Topics: Argon; Fullerenes; Phenylalanine; Silicon; Surface Properties; Thermodynamics; Tyrosine; Volatilization | 2014 |
α-Ketoacids as precursors for phenylalanine and tyrosine labelling in cell-based protein overexpression.
Topics: Escherichia coli; Isotope Labeling; Isotopes; Keto Acids; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Recombinant Proteins; Stereoisomerism; Tyrosine | 2013 |
An alternative pathway contributes to phenylalanine biosynthesis in plants via a cytosolic tyrosine:phenylpyruvate aminotransferase.
Topics: Alternative Splicing; Cytosol; Petunia; Phenylalanine; Phenylpyruvic Acids; Plant Proteins; RNA Interference; Transaminases; Tyrosine | 2013 |
Using unnatural amino acid mutagenesis to probe the regulation of PRMT1.
Topics: Amino Acid Substitution; Benzophenones; Cross-Linking Reagents; Histones; Humans; Immunoprecipitation; K562 Cells; Methylation; Mutagenesis, Site-Directed; Phenylalanine; Phosphorylation; Protein Processing, Post-Translational; Protein-Arginine N-Methyltransferases; Repressor Proteins; Substrate Specificity; Tyrosine | 2014 |
Intracellular boron accumulation in CHO-K1 cells using amino acid transport control.
Topics: Amino Acid Transport Systems; Animals; Boron Compounds; Boron Neutron Capture Therapy; CHO Cells; Cricetinae; Cricetulus; Drug Carriers; Metabolic Clearance Rate; Phenylalanine; Tyrosine | 2014 |
Dopamine precursor depletion impairs structure and efficiency of resting state brain functional networks.
Topics: Adult; Algorithms; Amino Acids; Brain; Brain Mapping; Dopamine; Double-Blind Method; Female; Humans; Magnetic Resonance Imaging; Male; Models, Neurological; Neural Pathways; Phenylalanine; Rest; Signal Processing, Computer-Assisted; Tyrosine; Young Adult | 2014 |
Phenylalanine and tyrosine methyl ester intramolecular interactions and conformational analysis by (1)H NMR and infrared spectroscopies and theoretical calculations.
Topics: Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrophotometry, Infrared; Tyrosine | 2014 |
Identification of nitrated tyrosine residues of protein kinase G-Iα by mass spectrometry.
Topics: Animals; Baculoviridae; Cyclic GMP-Dependent Protein Kinase Type I; Gene Expression; Humans; Kinetics; Mutation; Nitrates; Nitric Oxide; Peptide Fragments; Peroxynitrous Acid; Phenylalanine; Recombinant Proteins; Sf9 Cells; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spodoptera; Tandem Mass Spectrometry; Trypsin; Tyrosine | 2014 |
Elevated levels of plasma phenylalanine in schizophrenia: a guanosine triphosphate cyclohydrolase-1 metabolic pathway abnormality?
Topics: Adolescent; Adult; Case-Control Studies; Demography; Female; GTP Cyclohydrolase; Humans; Male; Metabolic Networks and Pathways; Middle Aged; Phenylalanine; Schizophrenia; Tyrosine; Young Adult | 2014 |
Neurocognitive evidence for revision of treatment targets and guidelines for phenylketonuria.
Topics: Adolescent; Child; Female; Humans; Male; Neuropsychological Tests; Phenylalanine; Phenylketonurias; Practice Guidelines as Topic; Tyrosine | 2014 |
Serum 1H-NMR metabolomic fingerprints of acute-on-chronic liver failure in intensive care unit patients with alcoholic cirrhosis.
Topics: Biomarkers; Creatinine; Glutamine; Humans; Intensive Care Units; Ketone Bodies; Lactic Acid; Liver Cirrhosis, Alcoholic; Liver Failure, Acute; Magnetic Resonance Spectroscopy; Metabolome; Multivariate Analysis; Phenylalanine; Pyruvic Acid; Tyrosine | 2014 |
p-Hydroxyphenylpyruvate, an intermediate of the Phe/Tyr catabolism, improves mitochondrial oxidative metabolism under stressing conditions and prolongs survival in rats subjected to profound hemorrhagic shock.
Topics: Animals; Cell Line; Cell Proliferation; Cell Respiration; Cell Survival; Hemodynamics; Humans; Metabolic Networks and Pathways; Mitochondria; Oxidation-Reduction; Phenylalanine; Phenylpyruvic Acids; Rats; Reactive Oxygen Species; Shock, Hemorrhagic; Stress, Physiological; Subcellular Fractions; Superoxides; Survival Analysis; Tyrosine | 2014 |
Effect of feeding garlic leaf on microbial nitrogen supply, kinetics of plasma phenylalanine, tyrosine and protein synthesis in sheep.
Topics: Animal Feed; Animals; Bacteria; Cross-Over Studies; Garlic; Kinetics; Male; Nitrogen; Phenylalanine; Plant Leaves; Protein Biosynthesis; Sheep; Tyrosine | 2014 |
The oxidative inactivation of FeFe hydrogenase reveals the flexibility of the H-cluster.
Topics: Hydrogen; Hydrogenase; Iron-Sulfur Proteins; Kinetics; Mutation; Oxidation-Reduction; Phenylalanine; Protein Conformation; Tyrosine | 2014 |
Tyrosine can protect against oxidative stress through ferryl hemoglobin reduction.
Topics: Antioxidants; Hemoglobins; Hep G2 Cells; Humans; Hydrogen Peroxide; Oxidation-Reduction; Oxidative Stress; Peroxidase; Phenylalanine; Serum Albumin; Tyrosine | 2014 |
DNA-protein π-interactions in nature: abundance, structure, composition and strength of contacts between aromatic amino acids and DNA nucleobases or deoxyribose sugar.
Topics: Amino Acids, Aromatic; Deoxyribose; DNA; DNA-Binding Proteins; Histidine; Models, Molecular; Phenylalanine; Protein Binding; Tryptophan; Tyrosine | 2014 |
Dopamine precursor depletion influences pain affect rather than pain sensation.
Topics: Adult; Dopamine; Electroencephalography; Healthy Volunteers; Humans; Male; Pain; Pain Perception; Pain Threshold; Phenylalanine; Synaptic Transmission; Tyrosine; Young Adult | 2014 |
Comparisons of interfacial Phe, Tyr, and Trp residues as determinants of orientation and dynamics for GWALP transmembrane peptides.
Topics: Mass Spectrometry; Membrane Proteins; Molecular Dynamics Simulation; Peptide Fragments; Peptides; Phenylalanine; Tryptophan; Tyrosine | 2014 |
An isotope dilution model for partitioning phenylalanine and tyrosine uptake by the mammary gland of lactating dairy cows.
Topics: Animals; Cattle; Dairying; Female; Lactation; Mammary Glands, Animal; Milk; Models, Theoretical; Phenylalanine; Radioisotope Dilution Technique; Tyrosine | 2014 |
Effects of feeding tyrosine and phenylalanine on the accumulation of phenylethanoid glycosides to Cistanche deserticola cell suspension culture.
Topics: Cell Culture Techniques; Cistanche; Culture Media; Glycosides; Phenylalanine; Tyrosine | 2014 |
Chronic Effect of Aspartame on Ionic Homeostasis and Monoamine Neurotransmitters in the Rat Brain.
Topics: Animals; Apoptosis; Aspartame; Cerebral Cortex; Corpus Striatum; Dopamine Antagonists; Male; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Non-Nutritive Sweeteners; Phenylalanine; Random Allocation; Rats, Wistar; Serotonin Antagonists; Sodium-Potassium-Exchanging ATPase; Toxicity Tests, Chronic; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase; Water-Electrolyte Imbalance | 2014 |
Performance of piglets in response to the standardized ileal digestible phenylalanine and tyrosine supply in low-protein diets.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet, Protein-Restricted; Dietary Supplements; Ileum; Male; Phenylalanine; Swine; Tyrosine | 2014 |
Impact of dietary aromatic amino acids on osteoclastic activity.
Topics: Amino Acids, Aromatic; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Diet; Dietary Supplements; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Phenylalanine; Real-Time Polymerase Chain Reaction; Tryptophan; Tyrosine | 2014 |
Dopamine precursors depletion impairs impulse control in healthy volunteers.
Topics: Adult; Disruptive, Impulse Control, and Conduct Disorders; Dopamine; Double-Blind Method; Female; Healthy Volunteers; Humans; Impulsive Behavior; Male; Phenylalanine; Randomized Controlled Trials as Topic; Tyrosine; Young Adult | 2015 |
Phylobiochemical characterization of class-Ib aspartate/prephenate aminotransferases reveals evolution of the plant arogenate phenylalanine pathway.
Topics: Amino Acid Sequence; Amino Acids, Dicarboxylic; Aspartate Aminotransferases; Bacterial Proteins; Biosynthetic Pathways; Chlorobium; Conserved Sequence; Cyclohexenes; Evolution, Molecular; Hydro-Lyases; Molecular Sequence Data; Mutagenesis, Site-Directed; Phenylalanine; Phylogeny; Plant Proteins; Plants; Sequence Alignment; Transaminases; Tyrosine | 2014 |
Molecular docking and molecular dynamics studies on the structure-activity relationship of fluoroquinolone for the HERG channel.
Topics: Animals; Binding Sites; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Fluoroquinolones; Humans; Molecular Docking Simulation; Molecular Dynamics Simulation; Phenylalanine; Structure-Activity Relationship; Tyrosine | 2014 |
Delineating the reaction mechanism of reductase domains of Nonribosomal Peptide Synthetases from mycobacteria.
Topics: Bacterial Proteins; Binding Sites; Binding, Competitive; Calorimetry; Catalytic Domain; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Mutation; Mycobacterium smegmatis; Mycobacterium tuberculosis; NADP; Niacinamide; Peptide Synthases; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Scattering, Small Angle; Thermodynamics; Tyrosine; X-Ray Diffraction | 2014 |
Synthesis of aromatic (13)C/(2)H-α-ketoacid precursors to be used in selective phenylalanine and tyrosine protein labelling.
Topics: Chemistry Techniques, Synthetic; Keto Acids; Phenylalanine; Proteins; Staining and Labeling; Tyrosine | 2014 |
Structural evolution of differential amino acid effector regulation in plant chorismate mutases.
Topics: Allosteric Regulation; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Chorismate Mutase; Chorismic Acid; Crystallography, X-Ray; Enzyme Activation; Escherichia coli; Evolution, Molecular; Gene Expression; Isoenzymes; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Phenylalanine; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine | 2014 |
[Interpretation of the consensus about the diagnosis and treatment of hyperphenylalaninemia].
Topics: Biopterins; Child; Consensus; Diagnosis, Differential; Humans; Infant; Infant, Newborn; Neonatal Screening; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Practice Guidelines as Topic; Severity of Illness Index; Tyrosine | 2014 |
Mechanistic and computational studies of the reductive half-reaction of tyrosine to phenylalanine active site variants of D-arginine dehydrogenase.
Topics: Amino Acid Oxidoreductases; Amino Acid Substitution; Bacterial Proteins; Biocatalysis; Catalytic Domain; Hydrolysis; Kinetics; Leucine; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutant Proteins; Oxidation-Reduction; Phenylalanine; Pseudomonas aeruginosa; Quantum Theory; Recombinant Proteins; Tyrosine; Viscosity | 2014 |
Excited State Dynamics of Protonated Phenylalanine and Tyrosine: Photo-Induced Reactions Following Electronic Excitation.
Topics: Electronics; Light; Models, Molecular; Phenylalanine; Quantum Theory; Tyrosine | 2015 |
Comparison of tandem mass spectrometry and amino acid analyzer for phenylalanine and tyrosine monitoring--implications for clinical management of patients with hyperphenylalaninemia.
Topics: Humans; Phenylalanine; Phenylketonurias; Tandem Mass Spectrometry; Tyrosine | 2015 |
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease.
Topics: alpha-Synuclein; Animals; Biomarkers; Chromatography, Liquid; Drosophila melanogaster; Fatty Acids; Histidine; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Nucleotides; Parkinson Disease; Phenotype; Phenylalanine; Steroids; Tryptophan; Tyrosine | 2015 |
An experimental and computational investigation into the gas-phase acidities of tyrosine and phenylalanine: three structures for deprotonated tyrosine.
Topics: Azides; Carboxylic Acids; Gases; Hydrogen-Ion Concentration; Kinetics; Molecular Conformation; Phenols; Phenylalanine; Protons; Quantum Theory; Silanes; Static Electricity; Stereoisomerism; Thermodynamics; Tyrosine | 2014 |
Fragmentation mechanism of UV-excited peptides in the gas phase.
Topics: Gases; Kinetics; Models, Chemical; Peptides; Phenylalanine; Photochemical Processes; Protons; Quantum Theory; Tyrosine; Ultraviolet Rays | 2014 |
A novel tyrosine-heme C−O covalent linkage in F43Y myoglobin: a new post-translational modification of heme proteins.
Topics: Amino Acid Substitution; Animals; Crystallography, X-Ray; Heme; Hydrogen Peroxide; Models, Molecular; Myoglobin; Oxidation-Reduction; Phenylalanine; Protein Conformation; Protein Processing, Post-Translational; Solutions; Spectrophotometry; Tyrosine; Whales | 2015 |
Simultaneous analysis of PhIP, 4'-OH-PhIP, and their precursors using UHPLC-MS/MS.
Topics: Animals; Chromatography, High Pressure Liquid; Cooking; Creatine; Creatinine; Glucose; Hot Temperature; Imidazoles; Meat; Phenylalanine; Swine; Tandem Mass Spectrometry; Tyrosine | 2014 |
Short communication: 3-phenyllactic acid production in milk by Pediococcus pentosaceus SK25 during laboratory fermentation process.
Topics: Animals; Anti-Infective Agents; Female; Fermentation; Lactates; Milk; Pediococcus; Phenylalanine; Sequence Analysis, DNA; Tyrosine | 2015 |
Mutations of the central tyrosines of putative cholesterol recognition amino acid consensus (CRAC) sequences modify folding, activity, and sterol-sensing of the human ABCG2 multidrug transporter.
Topics: Amino Acid Motifs; Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholesterol; Conserved Sequence; Gene Expression; HEK293 Cells; Humans; Molecular Sequence Data; Mutation; Neoplasm Proteins; Phenylalanine; Protein Folding; Recombinant Proteins; Serine; Sf9 Cells; Spodoptera; Tyrosine | 2015 |
Enhancement of L-phenylalanine production by engineered Escherichia coli using phased exponential L-tyrosine feeding combined with nitrogen source optimization.
Topics: Batch Cell Culture Techniques; Escherichia coli; Nitrogen; Phenylalanine; Tyrosine | 2015 |
Standardization of formulations for the acute amino acid depletion and loading tests.
Topics: Amino Acids, Branched-Chain; Animals; Humans; Phenylalanine; Rodentia; Species Specificity; Tryptophan; Tyrosine | 2015 |
Production of tyrosine through phenylalanine hydroxylation bypasses the intrinsic feedback inhibition in Escherichia coli.
Topics: Biosynthetic Pathways; Escherichia coli; Feedback, Physiological; Hydroxylation; Metabolic Engineering; Neopterin; Phenylalanine; Phenylalanine Hydroxylase; Shikimic Acid; Tyrosine; Xanthomonas campestris | 2015 |
d-Amino acids do not inhibit biofilm formation in Staphylococcus aureus.
Topics: Amino Acids; Bacillus subtilis; Biofilms; Molecular Structure; Phenylalanine; Proline; Staphylococcus aureus; Staphylococcus epidermidis; Stereoisomerism; Tryptophan; Tyrosine | 2015 |
Identification of a biochemical marker for endothelial dysfunction using Raman spectroscopy.
Topics: Animals; Aorta; Apolipoproteins E; Biomarkers; Endothelium, Vascular; Mice; Niacinamide; Phenylalanine; Spectrum Analysis, Raman; Tyrosine | 2015 |
Elevated fecal calprotectin in patients with Alzheimer's dementia indicates leaky gut.
Topics: Aged; Alzheimer Disease; Feces; Female; Humans; Leukocyte L1 Antigen Complex; Male; Phenylalanine; Tryptophan; Tyrosine | 2015 |
Equivalent Isopropanol Concentrations of Aromatic Amino Acids Interactions with Lipid Vesicles.
Topics: 2-Propanol; Glycerylphosphorylcholine; Magnetic Resonance Spectroscopy; Phenylalanine; Phosphatidylcholines; Phosphatidylserines; Tryptophan; Tyrosine | 2015 |
Deregulated tyrosine-phenylalanine metabolism in pulmonary tuberculosis patients.
Topics: Biomarkers; Discriminant Analysis; Gas Chromatography-Mass Spectrometry; Humans; Longitudinal Studies; Metabolic Networks and Pathways; Metabolome; Phenylalanine; Pilot Projects; ROC Curve; Tuberculosis, Pulmonary; Tyrosine | 2015 |
Long-term safety and efficacy of sapropterin: the PKUDOS registry experience.
Topics: Adolescent; Adult; Biopterins; Child; Child, Preschool; Diet; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenylalanine; Phenylketonurias; Registries; Time Factors; Tyrosine; Young Adult | 2015 |
HPLC for confirmatory diagnosis and biochemical monitoring of Cuban patients with hyperphenylalaninemias.
Topics: Chromatography, High Pressure Liquid; Cuba; Diagnosis, Differential; Female; Gestational Age; Humans; Infant, Newborn; Male; Monitoring, Physiologic; Neonatal Screening; Phenylalanine; Phenylketonurias; Retrospective Studies; Tyrosine | 2015 |
Normal level of sepsis-associated phenylcarboxylic acids in human serum.
Topics: Adult; Bacteria; Carboxylic Acids; Female; Humans; Male; Microbiota; Middle Aged; Phenylalanine; Sepsis; Tyrosine; Young Adult | 2015 |
Universal pathway for posttransfer editing reactions: insights from the crystal structure of TtPheRS with puromycin.
Topics: Amino Acids; Anti-Bacterial Agents; Binding Sites; Crystallization; Crystallography, X-Ray; Escherichia coli; Hydrogen Bonding; Hydrolysis; Ligands; Models, Molecular; Molecular Conformation; Phenylalanine; Phenylalanine-tRNA Ligase; Protein Multimerization; Protein Synthesis Inhibitors; Puromycin; Quantum Theory; Thermus thermophilus; Tyrosine | 2015 |
NMR Analysis of Tuning Cross-Strand Phe/Tyr/Trp-Trp Interactions in Designed β-Hairpin Peptides: Terminal Switch from L to D Amino Acid as a Strategy for β-Hairpin Capping.
Topics: Amino Acids, Aromatic; Drug Design; Magnetic Resonance Spectroscopy; Models, Molecular; Peptides; Phenylalanine; Protein Structure, Secondary; Stereoisomerism; Transition Temperature; Tryptophan; Tyrosine | 2015 |
NMR-based metabolomics highlights differences in plasma metabolites in pigs exhibiting diet-induced differences in adiposity.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Adiposity; Animal Feed; Animals; Biomarkers; Blood Glucose; Body Weight; Cholesterol, HDL; Cholesterol, LDL; Creatine; Creatinine; Diet; Dietary Fats; Dietary Fiber; Histidine; Insulin; Leptin; Linear Models; Lipid Metabolism; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Phenylalanine; Proline; Swine; Triglycerides; Tyrosine | 2016 |
Loss of Homogentisate 1,2-Dioxygenase Activity in Bacillus anthracis Results in Accumulation of Protective Pigment.
Topics: Anthrax; Bacillus anthracis; Bacterial Proteins; DNA Transposable Elements; Gene Deletion; Gene Expression Regulation, Bacterial; Homogentisate 1,2-Dioxygenase; Humans; Melanins; Mutagenesis; Oxidative Stress; Phenylalanine; Protective Agents; Tyrosine; Ultraviolet Rays | 2015 |
Fluorinated Aromatic Amino Acids Distinguish Cation-π Interactions from Membrane Insertion.
Topics: Amino Acid Sequence; Bacterial Proteins; Cations; Crystallography, X-Ray; Hydrophobic and Hydrophilic Interactions; Membrane Lipids; Models, Molecular; Molecular Sequence Data; Phenylalanine; Phosphoinositide Phospholipase C; Protein Binding; Protein Transport; Staphylococcus aureus; Tyrosine | 2015 |
Modelling of copper(II) binding to pentapeptides related to atrial natriuretic factor using the 3χv connectivity index.
Topics: Atrial Natriuretic Factor; Binding Sites; Cations; Copper; Models, Chemical; Molecular Structure; Oligopeptides; Phenylalanine; Protein Binding; Tyrosine | 2015 |
Newborn screening blood spot analysis in the UK: influence of spot size, punch location and haematocrit.
Topics: Amino Acids; Blood Specimen Collection; Carnitine; Dried Blood Spot Testing; Heel; Hematocrit; Humans; Infant, Newborn; Leucine; Linear Models; Methionine; Neonatal Screening; Phenylalanine; Thyrotropin; Trypsinogen; Tyrosine; United Kingdom | 2016 |
Two-step energy transfer enables use of phenylalanine in action-EET for distance constraint determination in gaseous biomolecules.
Topics: Disulfides; Energy Transfer; Gases; Models, Molecular; Molecular Conformation; Phenylalanine; Tyrosine | 2015 |
Identification of Api88 Binding Partners in Escherichia coli Using a Photoaffinity-Cross-Link Strategy and Label-Free Quantification.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Antimicrobial Cationic Peptides; Benzophenones; Blotting, Western; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cross-Linking Reagents; Escherichia coli; Escherichia coli Proteins; Insect Proteins; Microbial Sensitivity Tests; Molecular Sequence Data; Phenylalanine; Protein Binding; Protein Interaction Mapping; Protein Interaction Maps; Proteomics; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tyrosine; Ultraviolet Rays | 2015 |
Growth Responses of Juvenile Red Drum Sciaenops ocellatus to Dietary Phenylalanine and Tyrosine Can Be Used to Calculate the Total Aromatic Amino Acid Requirement.
Topics: Adiposity; Amino Acids, Aromatic; Animals; Aquaculture; Deficiency Diseases; Diet; Energy Intake; Fish Diseases; Fishes; Liver; Models, Biological; Muscle Development; Muscle, Skeletal; Nutritional Requirements; Organ Size; Phenylalanine; Seafood; Texas; Tyrosine; Weight Gain | 2015 |
Analysis of the Zidovudine Resistance Mutations T215Y, M41L, and L210W in HIV-1 Reverse Transcriptase.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Catalytic Domain; Cloning, Molecular; DNA, Viral; Escherichia coli; Gene Expression; HIV Reverse Transcriptase; HIV-1; Kinetics; Models, Molecular; Mutation; Phenylalanine; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA, Viral; Structure-Activity Relationship; Threonine; Tyrosine; Zidovudine | 2015 |
Quantitative analysis of phenylalanine, tyrosine, tryptophan and kynurenine in rat model for tauopathies by ultra-high performance liquid chromatography with fluorescence and mass spectrometry detection.
Topics: Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Humans; Kynurenine; Phenylalanine; Rats; Rats, Inbred SHR; Rats, Transgenic; Tandem Mass Spectrometry; Tauopathies; Tryptophan; Tyrosine | 2016 |
Identification of a plastidial phenylalanine exporter that influences flux distribution through the phenylalanine biosynthetic network.
Topics: Amino Acid Transport Systems, Basic; Biosynthetic Pathways; Escherichia coli; Metabolic Flux Analysis; Petunia; Phenylalanine; Plant Proteins; Plants, Genetically Modified; Plastids; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Sequence Analysis, RNA; Tyrosine; Volatile Organic Compounds | 2015 |
Phase transition of spindle-associated protein regulate spindle apparatus assembly.
Topics: Animals; HeLa Cells; Humans; Microtubule-Associated Proteins; Microtubules; Mitosis; Phenylalanine; Spindle Apparatus; Temperature; Tubulin; Tyrosine; Xenopus | 2015 |
Serum Phenylalanine, Tyrosine, and their Ratio in Acute Ischemic Stroke: on the Trail of a Biomarker?
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Brain Ischemia; Case-Control Studies; Female; Humans; Male; Middle Aged; Phenylalanine; Stroke; Tyrosine | 2016 |
Urinary biomarkers of oxidative stress and plasmatic inflammatory profile in phenylketonuric treated patients.
Topics: Adolescent; Biomarkers; Child; Creatine Kinase; Cytokines; Dinoprost; Female; Humans; Lipid Peroxidation; Male; Oxidative Stress; Phenylalanine; Phenylketonurias; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Tyrosine; Young Adult | 2015 |
Mechanism and pharmacological rescue of berberine-induced hERG channel deficiency.
Topics: Action Potentials; Berberine; Caveolin 1; Cell Membrane; Dose-Response Relationship, Drug; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Kinetics; Mutation; Phenylalanine; Potassium Channel Blockers; Resveratrol; RNA Interference; Stilbenes; Terfenadine; Transfection; Tyrosine | 2015 |
Molecular genetics of naringenin biosynthesis, a typical plant secondary metabolite produced by Streptomyces clavuligerus.
Topics: Acyl Coenzyme A; Acyltransferases; Amino Acid Sequence; Ammonia-Lyases; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Flavanones; Genome, Bacterial; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Sequence Data; Mutation; Phenylalanine; Plants; Sequence Alignment; Streptomyces; Tyrosine | 2015 |
Insulin Therapy of Nondiabetic Septic Patients Is Predicted by para-Tyrosine/Phenylalanine Ratio and by Hydroxyl Radical-Derived Products of Phenylalanine.
Topics: Aged; Aged, 80 and over; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Female; Glucose; Humans; Hydroxyl Radical; Insulin; Isomerism; Male; Middle Aged; Phenylalanine; Shock, Septic; Tyrosine | 2015 |
Syntheses of halogen derivatives of L-tryptophan, L-tyrosine and L-phenylalanine labeled with hydrogen isotopes.
Topics: Halogens; Phenylalanine; Radiopharmaceuticals; Tritium; Tryptophan; Tyrosine | 2016 |
Determination of Phenylalanine and Tyrosine by High Performance Liquid Chromatography-Tandem Mass Spectrometry.
Topics: Blood Chemical Analysis; Chromatography, High Pressure Liquid; Phenylalanine; Statistics as Topic; Tandem Mass Spectrometry; Tyrosine | 2016 |
β-Cyclodextrin preventing protein aggregation in foam fractionation of bovine serum albumin.
Topics: beta-Cyclodextrins; Chemical Fractionation; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Phenylalanine; Protein Aggregates; Serum Albumin, Bovine; Spectrum Analysis; Tyrosine | 2016 |
Addicting diverse bacteria to a noncanonical amino acid.
Topics: Amino Acids; Bacteria; beta-Lactamases; Biological Evolution; Codon; Gram-Negative Bacteria; Phenylalanine; Protein Engineering; RNA, Bacterial; RNA, Transfer; Tyrosine | 2016 |
The Effects of Acute Dopamine Precursor Depletion on the Reinforcing Value of Exercise in Anorexia Nervosa.
Topics: Adult; Affect; Anorexia Nervosa; Case-Control Studies; Convalescence; Diet, Protein-Restricted; Dopamine; Drive; Exercise; Female; Humans; Motivation; Phenylalanine; Reward; Self Report; Surveys and Questionnaires; Tyrosine; Video Games; Young Adult | 2016 |
Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations.
Topics: Adult; Aged; Amino Acids, Aromatic; Amino Acids, Branched-Chain; China; Chromatography, Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Isoleucine; Leucine; Longitudinal Studies; Male; Mass Spectrometry; Middle Aged; Phenylalanine; Risk Factors; Tyrosine; Valine; Young Adult | 2016 |
Phe362Tyr in AChE: A Major Factor Responsible for Azamethiphos Resistance in Lepeophtheirus salmonis in Norway.
Topics: Acetylcholinesterase; Amino Acid Substitution; Animals; Biological Assay; Copepoda; Genotype; Insecticide Resistance; Logistic Models; Mutation; Nonlinear Dynamics; Norway; Organothiophosphates; Phenylalanine; Spatial Analysis; Tyrosine | 2016 |
No Tryptophan, Tyrosine and Phenylalanine Abnormalities in Children with Attention-Deficit/Hyperactivity Disorder.
Topics: Adolescent; Attention Deficit and Disruptive Behavior Disorders; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Case-Control Studies; Child; Conduct Disorder; Diet; Dietary Proteins; Female; Humans; Male; Netherlands; Phenylalanine; Surveys and Questionnaires; Tryptophan; Tyrosine | 2016 |
Acute phenylalanine/tyrosine depletion of phasic dopamine in the rat brain.
Topics: Animals; Brain Chemistry; Dopamine; Male; Norepinephrine; Nucleus Accumbens; Phenylalanine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Tyrosine; Ventral Striatum | 2016 |
[Research on Early Diagnosis of Gastric Cancer by the Surface Enhanced Raman Spectroscopy of Human Hemoglobin].
Topics: Asparagine; Early Detection of Cancer; Heme; Hemoglobins; Humans; Methemoglobin; Multivariate Analysis; Oxyhemoglobins; Phenylalanine; Principal Component Analysis; Spectrum Analysis, Raman; Stomach Neoplasms; Tyrosine | 2015 |
The cysteine, total sulfur amino acid, tyrosine, phenylalanine + tyrosine, and non-essential amino acid maintenance requirements of broiler breeders.
Topics: Amino Acids; Amino Acids, Sulfur; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens; Cysteine; Diet; Female; Nutritional Requirements; Phenylalanine; Random Allocation; Tyrosine | 2016 |
Prooxidant-antioxidant balance in patients with phenylketonuria and its correlation to biochemical and hematological parameters.
Topics: Antioxidants; Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Reactive Oxygen Species; Tyrosine | 2016 |
Effects of Alpha-Ketoglutarate on Glutamine Metabolism in Piglet Enterocytes in Vivo and in Vitro.
Topics: Amino Acids; Animals; Arginine; Aspartic Acid; Body Weight; Citric Acid Cycle; Diet; Dietary Supplements; Enterocytes; Glutamine; Ileum; Intestinal Mucosa; Intestine, Small; Isoleucine; Jejunum; Ketoglutaric Acids; Lysine; Phenylalanine; RNA, Messenger; Swine; Tyrosine; Valine; Weaning | 2016 |
Serum Tyrosine-to-Phenylalanine Ratio is Low in Parkinson's Disease.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Parkinson Disease; Phenylalanine; Sweat; Tyrosine | 2016 |
Identification of a small protein domain present in all plant lineages that confers high prephenate dehydratase activity.
Topics: Amino Acids, Dicarboxylic; Cyclohexenes; Genes, Plant; Metabolic Networks and Pathways; Phenylalanine; Phenylpyruvic Acids; Phylogeny; Pinus; Plants; Prephenate Dehydratase; Tyrosine | 2016 |
Serum prolactin as a biomarker for the study of intracerebral dopamine effect in adult patients with phenylketonuria: a cross-sectional monocentric study.
Topics: Adolescent; Adult; Biomarkers; Cross-Sectional Studies; Dopamine Agents; Female; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Prognosis; Prolactin; Tyrosine; Young Adult | 2016 |
Rapid quantitative method for the detection of phenylalanine and tyrosine in human plasma using pillar array columns and gradient elution.
Topics: Humans; Lab-On-A-Chip Devices; Phenylalanine; Tyrosine | 2016 |
Conformational flexibility related to enzyme activity: evidence for a dynamic active-site gatekeeper function of Tyr(215) in Aerococcus viridans lactate oxidase.
Topics: Aerococcus; Bacterial Proteins; Catalytic Domain; Crystallography, X-Ray; Hydrogen Bonding; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Mixed Function Oxygenases; Molecular Dynamics Simulation; Mutation; Phenylalanine; Protein Conformation; Pyruvic Acid; Tyrosine | 2016 |
A Novel Urinary Metabolite Signature for Non-invasive Post-stroke Depression Diagnosis.
Topics: Aged; Biomarkers; Caproates; Case-Control Studies; Depression; Dicarboxylic Acids; Female; Glyceric Acids; Humans; Hydroxy Acids; Male; Metabolome; Middle Aged; Phenylalanine; Pseudouridine; Stroke; Tyrosine | 2015 |
Permeation of the three aromatic dipeptides through lipid bilayers: Experimental and computational study.
Topics: Hydrogen-Ion Concentration; Lipid Bilayers; Molecular Dynamics Simulation; Permeability; Phenylalanine; Phosphatidylcholines; Temperature; Time Factors; Tryptophan; Tyrosine; Water | 2016 |
Enantioseparation of the constituents involved in the phenylalanine-tyrosine metabolic pathway by capillary electrophoresis tandem mass spectrometry.
Topics: Animals; Cyclodextrins; Electrophoresis, Capillary; Formates; Limit of Detection; Male; Metabolic Networks and Pathways; Phenylalanine; Rats; Rats, Wistar; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Tandem Mass Spectrometry; Tyrosine | 2016 |
The Partitioning of Small Aromatic Molecules to Air-Water and Phospholipid Interfaces Mediated by Non-Hydrophobic Interactions.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Cluster Analysis; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Dynamics Simulation; Phenylalanine; Solubility; Spectrometry, Fluorescence; Surface Properties; Tyrosine; Unilamellar Liposomes; Water | 2016 |
Differential Laser-Induced Perturbation Spectroscopy for Analysis of Mixtures of the Fluorophores l-Phenylalanine, l-Tyrosine and l-Tryptophan Using a Fluorescence Probe.
Topics: Fluorescent Dyes; Lasers; Phenylalanine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2016 |
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult | 2016 |
Increased CSF levels of aromatic amino acids in hip fracture patients with delirium suggests higher monoaminergic activity.
Topics: Aged; Aged, 80 and over; Chromatography, Liquid; Delirium; Dementia; Female; Hip Fractures; Humans; Indoles; Male; Norway; Phenylalanine; Preoperative Care; Prospective Studies; Psychiatric Status Rating Scales; Reproducibility of Results; Tryptophan; Tyrosine | 2016 |
Structural Insights into Histone Crotonyl-Lysine Recognition by the AF9 YEATS Domain.
Topics: Amino Acid Motifs; Binding Sites; Cloning, Molecular; Crystallography, X-Ray; Escherichia coli; Gene Expression; Histones; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Lysine; Models, Molecular; Mutation; Nuclear Proteins; Phenylalanine; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Processing, Post-Translational; Recombinant Proteins; Tyrosine | 2016 |
Tryptophan Predicts the Risk for Future Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Isoleucine; Leucine; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Prognosis; Risk Factors; Tryptophan; Tyrosine; Valine | 2016 |
Preloading with L-BPA, L-tyrosine and L-DOPA enhances the uptake of [
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Caco-2 Cells; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Humans; Levodopa; Mice; Neoplasms, Experimental; Phenylalanine; Propionates; Tyrosine; Up-Regulation | 2016 |
Isoacceptor specific characterization of tRNA aminoacylation and misacylation in vivo.
Topics: Biotin; DNA Probes; Escherichia coli; Hydrolysis; Mass Spectrometry; Nucleic Acid Hybridization; Phenylalanine; Phenylalanine-tRNA Ligase; RNA, Transfer, Phe; RNA, Transfer, Tyr; Saccharomyces cerevisiae; Streptavidin; Transfer RNA Aminoacylation; Tyrosine; Tyrosine-tRNA Ligase | 2017 |
Resistance Exercise Augments Postprandial Overnight Muscle Protein Synthesis Rates.
Topics: Amino Acids; Blood Glucose; Caseins; Dietary Proteins; Humans; Insulin; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Postprandial Period; Resistance Training; Sleep; Tyrosine; Young Adult | 2016 |
First Report on Rare Unifloral Honey of Endemic Moltkia petraea (Tratt.) Griseb. from Croatia: Detailed Chemical Screening and Antioxidant Capacity.
Topics: Antioxidants; Boraginaceae; Chromatography, High Pressure Liquid; Croatia; Flavins; Gas Chromatography-Mass Spectrometry; Honey; Phenols; Phenylalanine; Pyrones; Solid Phase Microextraction; Sonication; Tyrosine | 2017 |
Stability improvement of natural food colors: Impact of amino acid and peptide addition on anthocyanin stability in model beverages.
Topics: Amino Acids; Anthocyanins; Ascorbic Acid; Citric Acid; Color; Daucus carota; Food Coloring Agents; Fruit and Vegetable Juices; Half-Life; Hydrogen-Ion Concentration; Peptides; Phenylalanine; Polylysine; Tryptophan; Tyrosine | 2017 |
Evidence that Illness-Compatible Cues Are Rewarding in Women Recovered from Anorexia Nervosa: A Study of the Effects of Dopamine Depletion on Eye-Blink Startle Responses.
Topics: Adult; Anorexia Nervosa; Blinking; Cues; Diet, Protein-Restricted; Dopamine; Female; Humans; Motivation; Phenylalanine; Reflex, Startle; Severity of Illness Index; Tyrosine; Young Adult | 2016 |
Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY.
Topics: Amino Acid Sequence; Chemistry, Pharmaceutical; Crystallography, X-Ray; Halogens; Humans; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Insulin; Models, Molecular; Phenylalanine; Protein Binding; Receptor, Insulin; Structure-Activity Relationship; Tyrosine | 2016 |
Post-Translational Incorporation of L-Phenylalanine into the C-Terminus of α-Tubulin as a Possible Cause of Neuronal Dysfunction.
Topics: Animals; Cell Line; Cell Proliferation; Cell Survival; Green Fluorescent Proteins; Humans; Mice; Microtubules; Neurites; Neurons; Phenylalanine; Phenylketonurias; Protein Processing, Post-Translational; Tubulin; Tyrosine | 2016 |
Tyr72 and Tyr80 are Involved in the Formation of an Active Site of a Luciferase of Copepod Metridia longa.
Topics: Amino Acid Sequence; Animals; Copepoda; Histidine; Isoenzymes; Kinetics; Luciferases; Luminescence; Phenylalanine; Sequence Homology, Amino Acid; Tyrosine | 2017 |
Structural Determinants of the Gain-of-Function Phenotype of Human Leukemia-associated Mutant CBL Oncogene.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Separation; Cytokines; Flow Cytometry; Gene Expression Regulation, Leukemic; Glutathione Transferase; Hematopoietic Stem Cells; Humans; Mice; Mice, Knockout; Mutagenesis; Mutant Proteins; Mutation; Oncogenes; Phenotype; Phenylalanine; Phosphorylation; Proline; Protein Domains; Proto-Oncogene Proteins c-cbl; Recombinant Fusion Proteins; Signal Transduction; Tyrosine | 2017 |
24-Hour protein, arginine and citrulline metabolism in fed critically ill children - A stable isotope tracer study.
Topics: Arginine; Carbon Isotopes; Child; Child, Preschool; Circadian Rhythm; Citrulline; Critical Illness; Dietary Proteins; Enteral Nutrition; Humans; Infant; Intensive Care Units; Leucine; Phenylalanine; Tyrosine | 2017 |
Glycomacropeptide in children with phenylketonuria: does its phenylalanine content affect blood phenylalanine control?
Topics: Adolescent; Amino Acids; Anthropometry; Caseins; Child; Diet; Female; Humans; Male; Micronutrients; Nutrition Assessment; Peptide Fragments; Phenylalanine; Phenylketonurias; Pilot Projects; Prospective Studies; Tyrosine | 2017 |
Growth, biogenic amine production and tyrDC transcription of Enterococcus faecalis in synthetic medium containing defined amino acid concentrations.
Topics: Biogenic Amines; Culture Media; Enterococcus faecalis; Phenylalanine; Transcription, Genetic; Tyramine; Tyrosine; Tyrosine Decarboxylase | 2017 |
Investigation of Fibril Forming Mechanisms of l-Phenylalanine and l-Tyrosine: Microscopic Insight toward Phenylketonuria and Tyrosinemia Type II.
Topics: Crown Ethers; Europium; Hydrogen Bonding; Kinetics; Macromolecular Substances; Phenylalanine; Phenylketonurias; Samarium; Terbium; Tyrosine; Tyrosinemias | 2017 |
Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability.
Topics: Alleles; Amino Acid Sequence; Biopterins; Case-Control Studies; Dopamine; Dystonia; Exons; Female; Fibroblasts; Gene Deletion; Genome-Wide Association Study; HSP70 Heat-Shock Proteins; Humans; Intellectual Disability; Male; Pedigree; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Repressor Proteins; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase | 2017 |
GC-MS Metabolomics Identifies Metabolite Alterations That Precede Subclinical Mastitis in the Blood of Transition Dairy Cows.
Topics: Animal Feed; Animals; Biomarkers; Cattle; Cell Count; Dairying; Early Diagnosis; Female; Gas Chromatography-Mass Spectrometry; Lactation; Mastitis, Bovine; Metabolomics; Milk; Parturition; Phenylalanine; Principal Component Analysis; Prognosis; Serine; Tyrosine; Valine | 2017 |
Editing of misaminoacylated tRNA controls the sensitivity of amino acid stress responses in Saccharomyces cerevisiae.
Topics: Amino Acids; Phenylalanine; Phenylalanine-tRNA Ligase; RNA Editing; RNA, Transfer, Amino Acyl; RNA, Transfer, Phe; Saccharomyces cerevisiae; Stress, Physiological; Transfer RNA Aminoacylation; Tyrosine; Unfolded Protein Response | 2017 |
Structural basis of mitochondrial dysfunction in response to cytochrome
Topics: Cytochromes c; Humans; Magnetic Resonance Spectroscopy; Mitochondria; Mutation; Oxidative Stress; Peroxidases; Phenylalanine; Phosphorylation; Protein Conformation; Reactive Oxygen Species; Signal Transduction; Tyrosine | 2017 |
Bilateral Effects of Excipients on Protein Stability: Preferential Interaction Type of Excipient and Surface Aromatic Hydrophobicity of Protein.
Topics: Arginine; Chemistry, Pharmaceutical; Colloids; Excipients; Humans; Hydrophobic and Hydrophilic Interactions; Ovalbumin; Phenylalanine; Propylene Glycols; Protein Conformation; Protein Stability; Serum Albumin, Bovine; Solubility; Solutions; Sorbitol; Sucrose; Surface Properties; Trehalose; Tryptophan; Tyrosine | 2017 |
An Efficient and Rapid Method to Monitor the Oxidative Degradation of Protein Pharmaceuticals: Probing Tyrosine Oxidation with Fluorogenic Derivatization.
Topics: Animals; Benzoxazoles; Calibration; Catalysis; Cattle; Drug Stability; Fluorescence; Human Growth Hormone; Humans; Immunoglobulin G; Insulin; Methionine; Oxidation-Reduction; Peroxides; Phenylalanine; Proteolysis; Serum Albumin, Bovine; Tyrosine | 2017 |
Characterization and comparison of recombinant honeybee chymotrypsin-like protease (HCLPase) expressed in Escherichia coli and insect cells.
Topics: Amino Acid Sequence; Animals; Baculoviridae; Bees; Cattle; Chymases; Cloning, Molecular; Escherichia coli; Gene Expression; Insect Proteins; Kinetics; Leucine; Oligopeptides; Peptide Fragments; Phenylalanine; Protease Inhibitors; Recombinant Proteins; Serum Albumin, Bovine; Sf9 Cells; Spodoptera; Substrate Specificity; Tyrosine | 2017 |
Biocatalytic Self-Assembly Cascades.
Topics: Alkaline Phosphatase; Amidohydrolases; Biocatalysis; Chromatography, High Pressure Liquid; Fluorenes; Kinetics; Microscopy, Electron, Transmission; Nanostructures; Phenylalanine; Phosphates; Spectrometry, Fluorescence; Thermodynamics; Thermolysin; Tyrosine | 2017 |
Detection of Localized Hepatocellular Amino Acid Kinetics by using Mass Spectrometry Imaging of Stable Isotopes.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Heterografts; Hydroxylation; Kinetics; Liver Neoplasms; Mass Spectrometry; Mice; Mice, Nude; Phenylalanine; Reproducibility of Results; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tandem Mass Spectrometry; Tyrosine | 2017 |
Altered tetrahydrobiopterin metabolism in patients with phenylalanine hydroxylase deficiency.
Topics: Adolescent; Adult; Biomarkers; Biopterins; Case-Control Studies; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Longitudinal Studies; Male; Multivariate Analysis; Neopterin; Phenylalanine; Phenylketonurias; Retrospective Studies; Tyrosine; Young Adult | 2017 |
Paediatric reference values for total homocysteine, tryptophan, tyrosine and phenylalanine in blood spots.
Topics: Child; Dried Blood Spot Testing; Female; Homocysteine; Humans; Male; Phenylalanine; Reference Values; Tryptophan; Tyrosine | 2017 |
Effect of long-distance transportation on serum metabolic profiles of steer calves.
Topics: Animals; Cattle; Citric Acid; Citric Acid Cycle; Gas Chromatography-Mass Spectrometry; Male; Molecular Weight; Niacin; Niacinamide; Phenylalanine; Propionates; Time Factors; Transportation; Tyrosine | 2017 |
Understanding the Reactivity of CO
Topics: Amino Acids; Carbonates; Cysteine; Electron Transport; Free Radicals; Histidine; Hydrogen; Methionine; Nitric Oxide; Phenylalanine; Sulfur; Tryptophan; Tyrosine | 2017 |
Calibration and validation of a carbon oxidation system and determination of the bicarbonate retention factor and the dietary phenylalanine requirement, in the presence of excess tyrosine, of adult, female, mixed-breed dogs,.
Topics: Animals; Bicarbonates; Calibration; Carbon; Carbon Isotopes; Carbon Monoxide; Diet; Dogs; Female; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Tyrosine | 2017 |
Tyrosinemia Type I in Japan: A Report of Five Cases.
Topics: Child, Preschool; Cyclohexanones; Female; Humans; Infant; Japan; Liver; Liver Transplantation; Male; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias | 2017 |
Unperturbed Immune Function despite Mutation of C-Terminal Tyrosines in Syk Previously Implicated in Signaling and Activity Regulation.
Topics: Animals; B-Lymphocytes; Cell Differentiation; Cell Line; Gene Knock-In Techniques; Humans; Mast Cells; Mice; Mutation; Phenylalanine; Signal Transduction; Syk Kinase; Tyrosine | 2017 |
Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells.
Topics: Action Potentials; Activating Transcription Factor 6; Berberine; Calnexin; Calreticulin; Drug Design; Ether-A-Go-Go Potassium Channels; Gene Expression Regulation; HEK293 Cells; HSP90 Heat-Shock Proteins; Humans; Patch-Clamp Techniques; Phenylalanine; Protein Folding; Protein Transport; Tyrosine; Unfolded Protein Response | 2017 |
A reassessment of the blood-brain barrier transport of large neutral amino acids during acute systemic inflammation in humans.
Topics: Adult; Amino Acids, Neutral; Blood Flow Velocity; Blood-Brain Barrier; Capillary Permeability; Cerebrovascular Circulation; Humans; Inflammation; Infusions, Intravenous; Lipopolysaccharides; Male; Models, Biological; Phenylalanine; Sepsis; Tyrosine; Young Adult | 2018 |
Fluorescence quenching, structural and unfolding studies of a purified cysteine protease, ZCPG from Zingiber montanum rhizome.
Topics: Amino Acid Motifs; Cysteine Proteases; Guanidine; Hydrogen-Ion Concentration; Phenylalanine; Plant Proteins; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Rhizome; Spectrometry, Fluorescence; Tryptophan; Tyrosine; Zingiberaceae | 2018 |
Interaction of manganese nanoparticle with cytochrome c: A multi-spectroscopic study.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cattle; Cytochromes c; Hydrophobic and Hydrophilic Interactions; Manganese; Metal Nanoparticles; Models, Molecular; Particle Size; Phenylalanine; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrum Analysis; Static Electricity; Temperature; Thermodynamics; Tryptophan; Tyrosine | 2018 |
Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation.
Topics: Amino Acid Motifs; Animals; Autophagosomes; Autophagy; Autophagy-Related Proteins; HEK293 Cells; Histidine; Humans; Mass Spectrometry; Phenylalanine; Rats; Tyrosine | 2017 |
Buyid Silk and the Tale of Bibi Shahrbanu: Identification of Biomarkers of Artificial Aging (Forgery) of Silk.
Topics: Amino Acids; Aspartic Acid; Biomarkers; Electrophoresis, Capillary; History, Medieval; Hydrogen-Ion Concentration; Isomerism; Mass Spectrometry; Phenylalanine; Radiometric Dating; Silk; Temperature; Textiles; Time Factors; Tyrosine | 2017 |
The mechanism (Phe362Tyr mutation) behind resistance in Lepeophtheirus salmonis pre-dates organophosphate use in salmon farming.
Topics: Animals; Aquaculture; Copepoda; Drug Resistance; Fish Diseases; Lice Infestations; Mutation; Norway; Organophosphates; Phenylalanine; Polymorphism, Single Nucleotide; Salmon; Tyrosine | 2017 |
Characterization and Elimination of Undesirable Protein Residues in Plant Cell Wall Materials for Enhancing Lignin Analysis by Solution-State Nuclear Magnetic Resonance Spectroscopy.
Topics: Amino Acids; Cell Wall; Cellulases; Hibiscus; Lignin; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Plant Proteins; Plants; Polymers; Tyrosine; Wood; Zea mays | 2017 |
A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites.
Topics: Amino Acids, Aromatic; Animals; Blood Chemical Analysis; Closterium; Gastrointestinal Microbiome; Germ-Free Life; Humans; Immunity; Indoles; Intestinal Mucosa; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Mice; Multigene Family; Permeability; Phenylalanine; Serum; Tryptophan; Tyrosine | 2017 |
Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Allosteric Regulation; Amino Acids, Aromatic; Chorismate Mutase; Corynebacterium glutamicum; Crystallography, X-Ray; Enzyme Activation; Models, Molecular; Phenylalanine; Protein Conformation; Protein Multimerization; Shikimic Acid; Tryptophan; Tyrosine | 2018 |
Biochemical and Structural Analysis of Substrate Specificity of a Phenylalanine Ammonia-Lyase.
Topics: Binding Sites; Catalytic Domain; Crystallography, X-Ray; Molecular Docking Simulation; Mutagenesis, Site-Directed; Phenylalanine; Phenylalanine Ammonia-Lyase; Phylogeny; Plant Proteins; Protein Conformation; Sorghum; Substrate Specificity; Thermodynamics; Tyrosine | 2018 |
An isotope dilution model for partitioning of phenylalanine and tyrosine uptake by the liver of lactating dairy cows.
Topics: Animals; Cattle; Female; Hepatic Artery; Isotopes; Lactation; Liver; Models, Theoretical; Phenylalanine; Portal Vein; Tyrosine | 2018 |
Patterns of cation binding to the aromatic amino acid R groups in Trp, Tyr, and Phe.
Topics: Cations; Cresols; Models, Chemical; Molecular Structure; Phenylalanine; Quantum Theory; Skatole; Sodium; Toluene; Tryptophan; Tyrosine | 2018 |
Electro-driven extraction of polar compounds using agarose gel as a new membrane: Determination of amino acids in fruit juice and human plasma samples.
Topics: Buffers; Calibration; Chromatography, High Pressure Liquid; Citrullus; Citrus paradisi; Electricity; Fruit and Vegetable Juices; Gels; Humans; Hydrogen-Ion Concentration; Limit of Detection; Liquid-Liquid Extraction; Membranes, Artificial; Phenylalanine; Polypropylenes; Sepharose; Tyrosine; Ultraviolet Rays | 2018 |
Relationships between tyrosine, phenylalanine, chlorogenic acid, and ascorbic acid concentrations and blackspot biochemical potential and blackspot susceptibility in stored russet potatoes.
Topics: Ascorbic Acid; Chlorogenic Acid; Food Storage; Phenylalanine; Plant Tubers; Solanum tuberosum; Tyrosine | 2018 |
Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Humans; Male; Mice, Nude; Neoplasm Metastasis; Phenylalanine; Prostatic Neoplasms; Reactive Oxygen Species; Serum; Signal Transduction; Subcutaneous Tissue; Tyrosine; Xenograft Model Antitumor Assays | 2018 |
Detection and scavenging of hydroxyl radical via D-phenylalanine hydroxylation in human fluids.
Topics: Adult; Chocolate; Diet; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Iron; Male; Middle Aged; Milk, Human; Phenylalanine; Pregnancy; Reproducibility of Results; Semen; Thiourea; Tyrosine; Young Adult | 2018 |
Plastic roles of phenylalanine and tyrosine residues of TLS/FUS in complex formation with the G-quadruplexes of telomeric DNA and TERRA.
Topics: Binding Sites; G-Quadruplexes; Humans; Models, Molecular; Phenylalanine; Protein Binding; Protein Domains; Protein Multimerization; RNA; RNA-Binding Protein FUS; Telomere; Telomere Shortening; Tyrosine | 2018 |
Excitonic Energy Landscape of the Y16F Mutant of the Chlorobium tepidum Fenna-Matthews-Olson (FMO) Complex: High Resolution Spectroscopic and Modeling Studies.
Topics: Bacterial Proteins; Chlorobium; Energy Transfer; Models, Molecular; Multiprotein Complexes; Phenylalanine; Photosynthesis; Spectrometry, Fluorescence; Tyrosine | 2018 |
Nitrogen compounds in Phacelia tanacetifolia Benth. honey: First time report on occurrence of (-)-5-epi-lithospermoside, uridine, adenine and xanthine in honey.
Topics: Acetonitriles; Adenine; Amino Acids; Boraginaceae; Glycosides; Honey; Nitrogen Compounds; Phenylalanine; Pollen; Tyrosine; Uridine; Xanthine | 2018 |
On the (un)coupling of the chromophore, tongue interactions, and overall conformation in a bacterial phytochrome.
Topics: Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Deinococcus; Models, Molecular; Phenylalanine; Phytochrome; Protein Conformation; Signal Transduction; Tyrosine | 2018 |
Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Boron Compounds; Crystallography, X-Ray; Escherichia coli; Methanocaldococcus; Mutation; Phenylalanine; Protein Conformation; Protein Engineering; Recombinant Proteins; RNA, Transfer; Substrate Specificity; Tyrosine | 2018 |
The ovarian estrogen synthesis function was impaired in Y123F mouse and partly restored by exogenous FSH supplement.
Topics: Amino Acid Substitution; Animals; Estradiol; Female; Follicle Stimulating Hormone; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovary; Phenylalanine; Receptors, Leptin; Tyrosine | 2018 |
Understanding Which Residues of the Active Site and Loop Structure of a Tyrosine Aminomutase Define Its Mutase and Lyase Activities.
Topics: Amino Acid Sequence; Catalytic Domain; Intramolecular Transferases; Lyases; Models, Molecular; Oryza; Phenylalanine; Plant Proteins; Protein Conformation; Sequence Alignment; Stereoisomerism; Substrate Specificity; Tyrosine | 2018 |
Altered metabolites in newborns with persistent pulmonary hypertension.
Topics: Area Under Curve; Birth Weight; Case-Control Studies; Female; Gestational Age; Humans; Infant, Newborn; Logistic Models; Male; Multivariate Analysis; Neonatal Screening; Ornithine; Persistent Fetal Circulation Syndrome; Phenylalanine; Respiration, Artificial; Thyrotropin; Treatment Outcome; Tyrosine | 2018 |
LatY136F knock-in mouse model for human IgG4-related disease.
Topics: Adaptor Proteins, Signal Transducing; Adrenal Cortex Hormones; Animals; Disease Models, Animal; Gene Knock-In Techniques; Humans; Immunoglobulin G4-Related Disease; Kidney; Leukocytes, Mononuclear; Lung; Membrane Proteins; Mice; Mutation; Pancreas; Phenotype; Phenylalanine; Phosphoproteins; Salivary Glands; Tyrosine | 2018 |
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult | 2018 |
Self-assembly and biological activities of ionic liquid crystals derived from aromatic amino acids.
Topics: Amino Acids, Aromatic; Animals; Calorimetry, Differential Scanning; Cell Line; Dihydroxyphenylalanine; Guanidine; Ions; Liquid Crystals; Mice; Phase Transition; Phenylalanine; Scattering, Small Angle; Staphylococcus aureus; Thermodynamics; Transition Temperature; Tyrosine; X-Ray Diffraction | 2018 |
Moderation of the relationship between Toxoplasma gondii seropositivity and trait impulsivity in younger men by the phenylalanine-tyrosine ratio.
Topics: Adult; Age Factors; Aged; Antibodies, Protozoan; Chromatography, High Pressure Liquid; Dopamine; Enzyme-Linked Immunosorbent Assay; Female; Germany; Healthy Volunteers; Humans; Immunoglobulin G; Impulsive Behavior; Kynurenine; Male; Middle Aged; Phenylalanine; Seroepidemiologic Studies; Serologic Tests; Sex Factors; Toxoplasma; Toxoplasmosis; Tryptophan; Tyrosine | 2018 |
Protein Kinase C-Delta (PKCδ) Tyrosine Phosphorylation is a Critical Regulator of Neutrophil-Endothelial Cell Interaction in Inflammation.
Topics: Animals; Apoptosis; Bone Marrow Cells; Cell Adhesion; Endothelial Cells; Endothelium, Vascular; Female; Fibronectins; Gene Knock-In Techniques; Inflammation; Male; Mice; Mice, Transgenic; Microcirculation; Microfluidics; Neutrophil Activation; Neutrophils; Oxygen; Permeability; Peroxidase; Phenylalanine; Phosphorylation; Protein Kinase C-delta; Sepsis; Superoxides; Tyrosine | 2019 |
Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway.
Topics: Amino Acid Sequence; Animals; Antiviral Agents; Cell Line; CSK Tyrosine-Protein Kinase; DEAD Box Protein 58; HEK293 Cells; Humans; Mice; Mice, Knockout; Phenylalanine; Phosphorylation; Receptors, Immunologic; Signal Transduction; src-Family Kinases; Transcription Factors; Tripartite Motif Proteins; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination | 2018 |
Self-assembled mechanism of hydrophobic amino acids and β-cyclodextrin based on experimental and computational methods.
Topics: Amino Acids; beta-Cyclodextrins; Calorimetry, Differential Scanning; Hydrogen Bonding; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Molecular Docking Simulation; Molecular Structure; Phenylalanine; Proteins; Proton Magnetic Resonance Spectroscopy; Solubility; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Taste; Tryptophan; Tyrosine | 2018 |
Phenyl alanine & Tyrosine Amino acids Coated Magnetic Nanoparticles: Preparation and Toxicity study.
Topics: Cell Survival; Drug Compounding; Erythrocytes; Green Chemistry Technology; HEK293 Cells; Hemolysis; Humans; Magnetite Nanoparticles; Materials Testing; Particle Size; Phenylalanine; Theranostic Nanomedicine; Toxicity Tests; Tyrosine | 2019 |
Identification of tyrosine autophosphorylation sites of Arabidopsis MEKK1 and their involvement in the regulation of kinase activity.
Topics: Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Escherichia coli; HEK293 Cells; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase Kinases; Mutation, Missense; Phenylalanine; Phosphorylation; Recombinant Proteins; Substrate Specificity; Tyrosine | 2018 |
Self-complementary and tyrosine-mutant rAAV vectors enhance transduction in cystic fibrosis bronchial epithelial cells.
Topics: Amino Acid Substitution; Bronchi; Cystic Fibrosis; Dependovirus; Epithelial Cells; Genetic Therapy; Genetic Vectors; Humans; Mutation; Phenylalanine; Serogroup; Transduction, Genetic; Tyrosine | 2018 |
Identification of a crucial amino acid responsible for the loss of specifying FGFR1-KLB affinity of the iodinated FGF21.
Topics: Amino Acids; Cell Line; Chloramines; Fibroblast Growth Factors; Halogenation; Homeostasis; Humans; Klotho Proteins; Membrane Proteins; Oxidation-Reduction; Phenylalanine; Protein Binding; Receptor, Fibroblast Growth Factor, Type 1; Signal Transduction; Sodium Iodide; Tosyl Compounds; Tyrosine | 2019 |
Time-dependent mucoadhesion of conjugated bioadhesive polymers.
Topics: Acrylic Resins; Adhesiveness; Adhesives; Animals; Butadienes; Hydrogen Bonding; Intestinal Mucosa; Intestine, Small; Levodopa; Maleic Anhydrides; Phenylalanine; Polymerization; Rats; Time Factors; Tissue Culture Techniques; Tyrosine | 2019 |
Transcription factor-based biosensor for detection of phenylalanine and tyrosine in urine for diagnosis of phenylketonuria.
Topics: Biosensing Techniques; Chromatography, High Pressure Liquid; Escherichia coli; Escherichia coli Proteins; Humans; Luminescent Proteins; Phenylalanine; Phenylketonurias; Repressor Proteins; Spectrometry, Mass, Electrospray Ionization; Transcription Factors; Tyrosine | 2018 |
Involvement of calcium-sensing receptor activation in the alleviation of intestinal inflammation in a piglet model by dietary aromatic amino acid supplementation.
Topics: Amino Acids, Aromatic; Animals; Colon; Cytokines; Diet; Dietary Supplements; Epithelial Cells; Female; I-kappa B Kinase; Inflammation; Intestines; Jejunum; Lipopolysaccharides; NF-kappa B; Peroxidase; Phenylalanine; Phosphorylation; Random Allocation; Receptors, Calcium-Sensing; RNA, Messenger; Signal Transduction; Sus scrofa; Swine; Tryptophan; Tumor Necrosis Factor-alpha; Tyrosine | 2018 |
Production of plant-specific flavones baicalein and scutellarein in an engineered E. coli from available phenylalanine and tyrosine.
Topics: Apigenin; Biosynthetic Pathways; Escherichia coli; Flavanones; Flavonoids; Malonyl Coenzyme A; Metabolic Engineering; Phenylalanine; Plants; Scutellaria baicalensis; Tyrosine | 2019 |
Self-assembly of aromatic amino acids: a molecular dynamics study.
Topics: Amino Acids, Aromatic; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Macromolecular Substances; Molecular Dynamics Simulation; Phenylalanine; Stereoisomerism; Temperature; Tryptophan; Tyrosine; Water | 2018 |
π-π stacking interaction is a key factor for the stability of GH11 xylanases at low pH.
Topics: Alanine; Amino Acid Sequence; Bacillus subtilis; Bacterial Proteins; Binding Sites; Cloning, Molecular; Endo-1,4-beta Xylanases; Escherichia coli; Gene Expression; Genetic Vectors; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Models, Molecular; Mutation; Phenylalanine; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tyrosine | 2019 |
Pyomelanin production: Insights into the incomplete aerobic l-phenylalanine catabolism of a photosynthetic bacterium, Rubrivivax benzoatilyticus JA2.
Topics: Aerobiosis; Betaproteobacteria; Cyclohexanones; Genome, Bacterial; Melanins; Mesylates; Phenylalanine; Photosynthesis; Phylogeny; Tyrosine; X-Ray Diffraction | 2019 |
Completion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants.
Topics: Amino Acids, Dicarboxylic; Biosynthetic Pathways; Chorismate Mutase; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytosol; Phenylalanine; Phenylpyruvic Acids; Plants; Plastids; Prephenate Dehydratase; Transaminases; Transcription Initiation Site; Tyrosine | 2019 |
Phenylalanine and tyrosine measurements across gestation by tandem mass spectrometer on dried blood spot cards from normal pregnant women.
Topics: Dried Blood Spot Testing; Female; Humans; Phenylalanine; Phenylketonuria, Maternal; Pregnancy; Pregnancy Complications; Reference Values; Tandem Mass Spectrometry; Tyrosine; Young Adult | 2019 |
Simultaneous quantification of multiple bacterial metabolites using surface-enhanced Raman scattering.
Topics: Ammonia-Lyases; Cinnamates; Coumaric Acids; Escherichia coli; Liquid-Liquid Extraction; Phenylalanine; Phenylalanine Ammonia-Lyase; Propionates; Spectrum Analysis, Raman; Tyrosine | 2019 |
Evidence for perturbed metabolic patterns in bipolar disorder subjects associated with lithium responsiveness.
Topics: Adult; Amino Acids, Branched-Chain; Bipolar Disorder; Dopamine; Female; Glutamic Acid; Homeostasis; Humans; Lithium Compounds; Male; Metabolome; Middle Aged; Phenylalanine; Psychotropic Drugs; Treatment Outcome; Tyrosine | 2019 |
Serum Metabolomics Analysis in Wasp Sting Patients.
Topics: Adult; Animals; Bites and Stings; Case-Control Studies; Female; Humans; Male; Metabolic Networks and Pathways; Metabolome; Metabolomics; Phenylalanine; Serum; Tryptophan; Tyrosine; Wasps | 2018 |
Gene Editing Successfully Corrects 2 Amino Acid Disorders: In 2 preclinical studies using CRISPR-mediated gene editing, phenylketonuria and hereditary tyrosinemia type 1 were corrected.
Topics: Amino Acids; Animals; CRISPR-Cas Systems; Disease Models, Animal; Gene Editing; Humans; Hydrolases; Mice; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine; Tyrosinemias | 2019 |
Effect of Chinese herbal medicine on kinetics of plasma phenylalanine, tyrosine and whole body protein synthesis in sheep.
Topics: Angelica; Animals; Astragalus Plant; Atractylodes; Cross-Over Studies; Diet; Drugs, Chinese Herbal; Fermentation; Male; Phenylalanine; Protein Biosynthesis; Rumen; Sheep; Tyrosine | 2019 |
Analysis of amino acids in blood by combining zeolitic imidazolate framework-8-based solid phase extraction and capillary electrophoresis.
Topics: Animals; Cattle; Electrophoresis, Capillary; Imidazoles; Limit of Detection; Nanoparticles; Phenylalanine; Solid Phase Extraction; Tryptophan; Tyrosine; Zeolites | 2019 |
A reduced concentration of brain interstitial amino acids is associated with depression in subarachnoid hemorrhage patients.
Topics: Aged; Amino Acids; Brain; Depression; Female; Humans; Male; Microdialysis; Middle Aged; Phenylalanine; Subarachnoid Hemorrhage; Tryptophan; Tyrosine | 2019 |
Crystal structure of a domain-swapped photoactivatable sfGFP variant provides evidence for GFP folding pathway.
Topics: Amino Acids; Amino Acyl-tRNA Synthetases; Crystallography, X-Ray; Escherichia coli; Green Fluorescent Proteins; Methanocaldococcus; Molecular Imaging; Mutation; Phenylalanine; Protein Conformation; Protein Folding; RNA, Transfer; Tyrosine | 2019 |
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2.
Topics: Animals; Blood Circulation; Boron Compounds; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Humans; Large Neutral Amino Acid-Transporter 1; Male; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Rats; Tissue Distribution; Tyrosine | 2019 |
Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.
Topics: Animals; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Peptide Transporter 1; Phenylalanine; Symporters; Tyrosine; Up-Regulation; Xenograft Model Antitumor Assays | 2019 |
Alterations in the tyrosine and phenylalanine pathways revealed by biochemical profiling in cerebrospinal fluid of Huntington's disease subjects.
Topics: Adult; Aged; Biomarkers; Dopamine; Female; Humans; Huntington Disease; Levodopa; Male; Middle Aged; Phenylalanine; Thyroxine; Tyrosine | 2019 |
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid.
Topics: Emulsions; Lysine; Nanostructures; Oleic Acid; Peptides; Phenylalanine; Platinum; Tyrosine | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
How acute and chronic physical disease may influence mental health - An Analysis of neurotransmitter precursor amino acid levels.
Topics: Acute Disease; Adult; Aged; Amino Acids; Anxiety Disorders; C-Reactive Protein; Chronic Disease; Depression; Depressive Disorder; Female; Humans; Inflammation; Kynurenine; Male; Mental Disorders; Mental Health; Middle Aged; Neurotransmitter Agents; Phenylalanine; Prospective Studies; Tryptophan; Tyrosine | 2019 |
Effect of low-temperature storage on the content of folate, vitamin B
Topics: Ascorbic Acid; Chlorogenic Acid; Cold Temperature; Folic Acid; Food Storage; Nutritive Value; Phenylalanine; Plant Tubers; Solanum tuberosum; Tyrosine; Vitamin B 6 | 2019 |
An inner activation gate controls TMEM16F phospholipid scrambling.
Topics: Anoctamin-1; Anoctamins; Cell Membrane; Gene Knockout Techniques; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Ion Channel Gating; Isoleucine; Lysine; Mutagenesis; Phenylalanine; Phospholipid Transfer Proteins; Phospholipids; Tyrosine | 2019 |
Chiral Capillary Electrophoresis-Mass Spectrometry.
Topics: Animals; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Mass Spectrometry; Phenylalanine; Rats; Stereoisomerism; Tyrosine | 2019 |
The Association of Aromatic Amino Acids with Incident Hip Fracture, aBMD, and Body Composition from the Cardiovascular Health Study.
Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Aging; Amino Acids, Aromatic; Body Composition; Body Mass Index; Bone Density; Diet; Diet Surveys; Ethnicity; Female; Hip Fractures; Humans; Male; Multivariate Analysis; Osteoporosis; Phenylalanine; Risk; Tryptophan; Tyrosine | 2019 |
N-Substituted amino acid inhibitors of the phosphatase domain of the soluble epoxide hydrolase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Enzyme Inhibitors; Epoxide Hydrolases; Epoxy Compounds; Humans; Hydrolysis; Kinetics; Mice; Phenylalanine; Phosphoric Monoester Hydrolases; Solubility; Species Specificity; Tyrosine | 2019 |
Methionine and Selenomethionine as Energy Transfer Acceptors for Biomolecular Structure Elucidation in the Gas Phase.
Topics: Carbon; Energy Transfer; Gases; Mass Spectrometry; Methionine; Models, Molecular; Molecular Dynamics Simulation; Peptides; Phenylalanine; Selenomethionine; Sulfur; Tryptophan; Tyrosine | 2019 |
How
Topics: Environmental Microbiology; Humans; Legionella pneumophila; Legionnaires' Disease; Phenylalanine; Tyrosine | 2019 |
A chiral signal-amplified sensor for enantioselective discrimination of amino acids based on charge transfer-induced SERS.
Topics: Aniline Compounds; beta-Cyclodextrins; Hydrogen Bonding; Metal Nanoparticles; Phenylalanine; Silver; Spectrum Analysis, Raman; Stereoisomerism; Sulfhydryl Compounds; Titanium; Tryptophan; Tyrosine | 2019 |
The interaction between methionine and two aromatic amino acids is an abundant and multifunctional motif in proteins.
Topics: Algorithms; Chemical Phenomena; Databases, Protein; Humans; Methionine; Molecular Structure; Phenylalanine; Proteins; Tryptophan; Tyrosine | 2019 |
Recurrent convergent evolution at amino acid residue 261 in fish rhodopsin.
Topics: Adaptation, Biological; Amino Acid Substitution; Animals; Evolution, Molecular; Fish Proteins; Fishes; Genetic Loci; Phenylalanine; Protein Conformation, alpha-Helical; Rhodopsin; Selection, Genetic; Sequence Homology, Amino Acid; Structure-Activity Relationship; Tyrosine; Vision, Ocular; Whole Genome Sequencing | 2019 |
Dietary restriction of tyrosine and phenylalanine lowers tyrosinemia associated with nitisinone therapy of alkaptonuria.
Topics: Alkaptonuria; Animals; Cyclohexanones; Diet, Protein-Restricted; Female; Humans; Male; Mice; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias | 2020 |
Loss of Single-Domain Function in a Modular Assembly Line Alters the Size and Shape of a Complex Polyketide.
Topics: Chromones; Microorganisms, Genetically-Modified; Mutagenesis; Phenylalanine; Point Mutation; Polyketide Synthases; Polyketides; Protein Domains; Pyrones; Streptomyces; Tyrosine | 2019 |
[Early diagnosis of phenylketonuria. Physiopathology of the neuronal damage and therapeutic options].
Topics: Biopterins; Diet Therapy; Early Diagnosis; Humans; Neurons; Phenylalanine; Phenylketonurias; Tyrosine | 2019 |
Homogentisic acid is not only eliminated by glomerular filtration and tubular secretion but also produced in the kidney in alkaptonuria.
Topics: Adult; Alkaptonuria; Case-Control Studies; Creatinine; Female; Glomerular Filtration Rate; Homogentisic Acid; Humans; Kidney; Linear Models; Male; Middle Aged; Ochronosis; Phenylalanine; Sex Factors; Tyrosine | 2020 |
Photodetachment of deprotonated aromatic amino acids: stability of the dehydrogenated radical depends on the deprotonation site.
Topics: Amines; Amino Acids, Aromatic; Anions; Carbon Dioxide; Light; Phenylalanine; Photolysis; Protons; Tryptophan; Tyrosine | 2019 |
Metabolomics analysis revealed significantly higher synovial Phe/Tyr ratio in reactive arthritis and undifferentiated spondyloarthropathy.
Topics: Adolescent; Adult; Aged; Arthritis, Reactive; Arthritis, Rheumatoid; Case-Control Studies; Female; Humans; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Osteoarthritis; Phenylalanine; Prohibitins; Spondylarthropathies; Synovial Fluid; Tyrosine; Young Adult | 2020 |
Metabolic engineering of Synechocystis sp. PCC 6803 for the production of aromatic amino acids and derived phenylpropanoids.
Topics: Escherichia coli; Escherichia coli Proteins; Metabolic Engineering; Phenylalanine; Phenylpropionates; Synechocystis; Tyrosine | 2020 |
The Effect of Various Doses of Phenylalanine Supplementation on Blood Phenylalanine and Tyrosine Concentrations in Tyrosinemia Type 1 Patients.
Topics: Adolescent; Adult; Child; Cyclohexanones; Dietary Supplements; Enzyme Inhibitors; Female; Heptanoates; Humans; Linear Models; Male; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias; Young Adult | 2019 |
Emotional and behavioral problems, quality of life and metabolic control in NTBC-treated Tyrosinemia type 1 patients.
Topics: Adolescent; Adult; Child; Cyclohexanones; Humans; Male; Nitrobenzoates; Phenylalanine; Quality of Life; Tyrosine; Tyrosinemias; Young Adult | 2019 |
Binding Loop Substitutions in the Cyclic Peptide SFTI-1 Generate Potent and Selective Chymase Inhibitors.
Topics: Amino Acid Substitution; Angiotensin II; Chymases; Crystallography, X-Ray; Drug Design; High-Throughput Screening Assays; Humans; Models, Molecular; Molecular Dynamics Simulation; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Serine Proteinase Inhibitors; Small Molecule Libraries; Structure-Activity Relationship; Tyrosine | 2020 |
Metabolomic profile overlap in prototypical autoimmune humoral disease: a comparison of myasthenia gravis and rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Female; Humans; Male; Metabolic Networks and Pathways; Metabolome; Middle Aged; Myasthenia Gravis; Phenylalanine; Pyruvic Acid; Tyrosine; Ubiquinone | 2020 |
Arogenate dehydratases can modulate the levels of phenylacetic acid in Arabidopsis.
Topics: Amino Acids, Dicarboxylic; Arabidopsis; Cyclohexenes; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Hydro-Lyases; Indoleacetic Acids; Mutation; Phenylacetates; Phenylalanine; Plants, Genetically Modified; Tyrosine | 2020 |
Construction of a switchable synthetic Escherichia coli for aromatic amino acids by a tunable switch.
Topics: Escherichia coli; Metabolic Engineering; Phenylalanine; Tryptophan; Tyrosine | 2020 |
Metabolic and catecholamine response to sympathetic stimulation in early-treated adult male patients with phenylketonuria.
Topics: Adolescent; Adult; Epinephrine; Humans; Male; Norepinephrine; Phenylalanine; Phenylketonurias; Physical Exertion; Stress, Physiological; Sympathetic Nervous System; Tyrosine; Young Adult | 2020 |
Valence and patterning of aromatic residues determine the phase behavior of prion-like domains.
Topics: Amino Acid Sequence; Heterogeneous Nuclear Ribonucleoprotein A1; Magnetic Resonance Spectroscopy; Phase Transition; Phenylalanine; Prions; Protein Domains; Scattering, Small Angle; Tyrosine; X-Ray Diffraction | 2020 |
Birth weight related blood concentrations of the neurotransmission amino acids glutamine plus glutamate, phenylalanine and tyrosine in full-term breastfed infants perinatally.
Topics: Amino Acids; Birth Weight; Breast Feeding; Female; Glutamic Acid; Glutamine; Humans; Infant, Newborn; Male; Neurotransmitter Agents; Phenylalanine; Reference Values; Sex Characteristics; Tyrosine | 2020 |
Honey as Source of Nitrogen Compounds: Aromatic Amino Acids, Free Nucleosides and Their Derivatives.
Topics: Adenine; Amino Acids, Aromatic; Chromatography, High Pressure Liquid; Fagopyrum; Honey; Mass Spectrometry; Nitrogen Compounds; Nucleosides; Phenylalanine; Tilia; Tyrosine; Uridine; Xanthine | 2020 |
Nitisinone causes acquired tyrosinosis in alkaptonuria.
Topics: Adult; Aged; Alkaptonuria; Amino Acid Metabolism, Inborn Errors; Animals; Cyclohexanones; Female; Humans; Male; Mice; Mice, Inbred BALB C; Middle Aged; Nitrobenzoates; Phenylalanine; Tyrosine; Young Adult | 2020 |
Protein Requirements of Elderly Chinese Adults Are Higher than Current Recommendations.
Topics: Aged; Aging; Amino Acids; Body Weight; China; Dietary Proteins; Energy Intake; Energy Metabolism; Female; Humans; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Recommended Dietary Allowances; Tyrosine | 2020 |
Urine metabolomic analysis for monitoring internal load in professional football players.
Topics: Adolescent; Amino Acids; Gonadal Steroid Hormones; Humans; Hypoxanthine; Least-Squares Analysis; Male; Metabolomics; Phenylalanine; Riboflavin; Soccer; Tryptophan; Tyrosine; Young Adult | 2020 |
Dried blood spot versus venous blood sampling for phenylalanine and tyrosine.
Topics: Amino Acids; Dried Blood Spot Testing; Humans; Phenylalanine; Phenylketonurias; Tyrosine | 2020 |
Enhancing the selectivity of liquid chromatography-mass spectrometry by using trilinear decomposition on LC-MS data: An application to three-way calibration of coeluting analytes in human plasma.
Topics: Algorithms; Calibration; Chromatography, Liquid; Humans; Mass Spectrometry; Phenylalanine; Software; Tryptophan; Tyrosine | 2020 |
Chromosome Engineering To Generate Plasmid-Free Phenylalanine- and Tyrosine-Overproducing
Topics: Bacteria; Chromosomes, Bacterial; Escherichia coli; Genetic Engineering; Phenylalanine; Plasmids; Tyrosine | 2020 |
Sexual Dimorphism in Energy Metabolism of Wistar Rats Using Data Analysis.
Topics: Amino Acids; Animals; Biomarkers; Carnitine; Data Analysis; Discriminant Analysis; Energy Metabolism; Female; Male; Metabolome; Metabolomics; Phenylalanine; Rats; Sex Characteristics; Tyrosine | 2020 |
Insights into the FMNAT Active Site of FAD Synthase: Aromaticity is Essential for Flavin Binding and Catalysis.
Topics: Bacterial Proteins; Catalytic Domain; Corynebacterium; Dinitrocresols; Hydrophobic and Hydrophilic Interactions; Mutation; Nucleotidyltransferases; Phenylalanine; Protein Binding; Tyrosine | 2020 |
Chimeric design of pyrrolysyl-tRNA synthetase/tRNA pairs and canonical synthetase/tRNA pairs for genetic code expansion.
Topics: Alanine; Amino Acids; Chimera; Escherichia coli; Genetic Code; HEK293 Cells; Histidine; Humans; Lysine; Phenylalanine; RNA, Transfer; Synthetic Biology; Tryptophan; Tyrosine | 2020 |
Discovery and engineering of colchicine alkaloid biosynthesis.
Topics: Biosynthetic Pathways; Colchicaceae; Colchicine; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Plant; Metabolic Engineering; Metabolomics; Nicotiana; Phenylalanine; Transcriptome; Tyrosine | 2020 |
Tryptophan degradation is associated with risk-taking propensity in methamphetamine users with treated HIV infection.
Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biotransformation; Cross-Sectional Studies; HIV Infections; Homosexuality, Male; Humans; Impulsive Behavior; Kynurenine; Male; Methamphetamine; Middle Aged; Phenylalanine; Psychological Tests; Risk-Taking; Substance-Related Disorders; Tryptophan; Tyrosine; Viral Load | 2020 |
Phenylalanine and tyrosine metabolism in DNAJC12 deficiency: A comparison between inherited hyperphenylalaninemias and healthy subjects.
Topics: Adult; Female; Humans; Infant, Newborn; Male; Phenylalanine; Phenylketonurias; Repressor Proteins; Tyrosine | 2020 |
The second N-terminal aromatic residue of the fungal defensin, blapersin, of Blastomyces percursus is essential for its antibacterial activity.
Topics: Alanine; Amino Acid Substitution; Anti-Bacterial Agents; Blastomyces; Defensins; Fungal Proteins; Gram-Positive Bacteria; HEK293 Cells; Hemolysis; Humans; Microbial Sensitivity Tests; Models, Molecular; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Tryptophan; Tyrosine | 2020 |
Plasma phenylalanine and tyrosine and their interactions with diabetic nephropathy for risk of diabetic retinopathy in type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Humans; Phenylalanine; Tyrosine | 2020 |
Effect of active-site aromatic residues Tyr or Phe on activity and stability of glucose 6-phosphate dehydrogenase from psychrophilic Arctic bacterium Sphingomonas sp.
Topics: Adaptation, Physiological; Amino Acid Substitution; Bacterial Proteins; Binding Sites; Biocatalysis; Cold Temperature; Gene Expression; Glucose-6-Phosphate; Glucosephosphate Dehydrogenase; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Docking Simulation; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Sphingomonas; Substrate Specificity; Tryptophan; Tyrosine | 2021 |
Theoretical Research on Excited States: Ultraviolet and Fluorescence Spectra of Aromatic Amino Acids.
Topics: Amino Acids; Amino Acids, Aromatic; Phenylalanine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2020 |
Tyrosine-phosphorylation and activation of glucosylceramide synthase by v-Src: Its role in survival of HeLa cells against ceramide.
Topics: 4-Chloro-7-nitrobenzofurazan; Cell Survival; Ceramides; Enzyme Activation; Glucosylceramides; Glucosyltransferases; HEK293 Cells; HeLa Cells; Humans; Mutation; Oncogene Protein pp60(v-src); Phenylalanine; Phosphorylation; Tyrosine; Uridine Diphosphate Glucose | 2021 |
Assessment of serum phenylalanine and tyrosine isomers in patients with ST-segment elevation vs non-ST-segment elevation myocardial infarction.
Topics: Acute Coronary Syndrome; Aged; Female; Humans; Isomerism; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Phenylalanine; Prospective Studies; ST Elevation Myocardial Infarction; Tyrosine | 2021 |
Overexpression of OsCM alleviates BLB stress via phytohormonal accumulation and transcriptional modulation of defense-related genes in Oryza sativa.
Topics: Chorismate Mutase; Cloning, Molecular; Disease Resistance; Gene Expression Regulation, Plant; Lignin; Oryza; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Diseases; Plant Growth Regulators; Plant Proteins; Plants, Genetically Modified; Salicylic Acid; Stress, Physiological; Transcription, Genetic; Tyrosine; Xanthomonas | 2020 |
Dietary Aromatic Amino Acid Requirements During Early and Late Gestation in Healthy Pregnant Women.
Topics: Adult; Amino Acids, Aromatic; Carbon Isotopes; Female; Humans; Isotope Labeling; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnant Women; Tyrosine | 2020 |
Benchmark Examination of Blood Amino Acids Patterns in Phenylketonuria Neonates and Young Children on Phenylalanine-Restricted Dietary Treatment.
Topics: Arginine; Benchmarking; Child; Child, Preschool; Citrulline; Diet; Humans; Infant, Newborn; Methionine; Phenylalanine; Phenylketonurias; Proline; Tyrosine; Valine | 2022 |
Meta-Tyrosine Induces Cytotoxic Misregulation of Metabolism in Escherichia coli.
Topics: Amino Acyl-tRNA Synthetases; Bacterial Proteins; Escherichia coli; Escherichia coli Proteins; Guanosine Tetraphosphate; Oxidative Stress; Phenylalanine; Protein Aggregates; Proteome; Repressor Proteins; Tyrosine | 2020 |
Case report: Maternal tyrosinemia type 1a under NTBC treatment with tyrosine- and phenylalanine restricted diet in Chile.
Topics: Adolescent; Chile; Diet; Female; Humans; Phenylalanine; Tyrosine; Tyrosinemias | 2020 |
Hepatorenal Tyrosinaemia: Impact of a Simplified Diet on Metabolic Control and Clinical Outcome.
Topics: Adolescent; Austria; Child; Child, Preschool; Combined Modality Therapy; Cyclohexanones; Diet, Protein-Restricted; Dietary Proteins; Enzyme Inhibitors; Female; Germany; Humans; Male; Nitrobenzoates; Patient Compliance; Phenylalanine; Practice Guidelines as Topic; Prospective Studies; Retrospective Studies; Surveys and Questionnaires; Switzerland; Treatment Outcome; Tyrosine; Tyrosinemias; Young Adult | 2020 |
Colorimetric recognition of aromatic amino acid enantiomers by gluconic acid-capped gold nanoparticles.
Topics: Colorimetry; Gluconates; Gold; Metal Nanoparticles; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine | 2021 |
Capillary electrophoresis and molecular modeling of the chiral separation of aromatic amino acids using α/β-cyclodextrin and 18-crown-6.
Topics: alpha-Cyclodextrins; Amines; Amino Acids; Amino Acids, Aromatic; beta-Cyclodextrins; Crown Ethers; Electrophoresis, Capillary; Phenylalanine; Stereoisomerism; Tryptophan; Tyrosine | 2021 |
A Single-Point Mutation in d-Arginine Dehydrogenase Unlocks a Transient Conformational State Resulting in Altered Cofactor Reactivity.
Topics: Amino Acid Oxidoreductases; Binding Sites; Catalysis; Catalytic Domain; Flavins; Kinetics; Molecular Dynamics Simulation; Mutagenesis, Site-Directed; Phenylalanine; Point Mutation; Protein Conformation; Pseudomonas aeruginosa; Tyrosine | 2021 |
Structural features of the plant N-recognin ClpS1 and sequence determinants in its targets that govern substrate selection.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Arabidopsis; Arabidopsis Proteins; Binding Sites; Carrier Proteins; Chloroplasts; Cloning, Molecular; Conserved Sequence; Escherichia coli; Escherichia coli Proteins; Gene Expression; Genetic Vectors; Leucine; Models, Molecular; Phenylalanine; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Proteolysis; Recombinant Proteins; Substrate Specificity; Tryptophan; Tyrosine | 2021 |
The entry reaction of the plant shikimate pathway is subjected to highly complex metabolite-mediated regulation.
Topics: Amino Acids, Dicarboxylic; Arabidopsis; Cyclohexenes; Phenylalanine; Seedlings; Shikimic Acid; Tryptophan; Tyrosine | 2021 |
Untargeted UHPLC-MS metabolic profiling as a valuable tool for the evaluation of eggs quality parameters after dietary supplementation with oregano, thyme, sideritis tea and chamomile on brown laying hens.
Topics: Animal Feed; Animals; Chamomile; Chickens; Chromatography, High Pressure Liquid; Diet; Dietary Supplements; Female; Origanum; Phenylalanine; Plant Extracts; Sideritis; Tea; Thymus Plant; Tyrosine | 2021 |
Treatment adherence in tyrosinemia type 1 patients.
Topics: Adolescent; Adult; Child; Child, Preschool; Cyclohexanones; Humans; Infant; Nitrobenzoates; Phenylalanine; Prognosis; Treatment Adherence and Compliance; Tyrosine; Tyrosinemias; Young Adult | 2021 |
3D Interaction Homology: Hydropathic Analyses of the "π-Cation" and "π-π" Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues.
Topics: Cations; Phenylalanine; Proteins; Tryptophan; Tyrosine | 2021 |
Mass spectrometry-based urinary metabolomics for exploring the treatment effects of Radix ginseng-Schisandra chinensis herb pair on Alzheimer's disease in rats.
Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Inflammation; Mass Spectrometry; Medicine, Chinese Traditional; Metabolomics; Nervous System; Panax; Phenylalanine; Plant Extracts; Rats; Reproducibility of Results; Schisandra; Tandem Mass Spectrometry; Tyrosine; Urinalysis | 2021 |
Molecule-specific vibration-based chiral differentiation of Raman spectra using cysteine modified gold nanoparticles: the cases of tyrosine and phenylalanine.
Topics: Biocompatible Materials; Cysteine; Gold; Materials Testing; Metal Nanoparticles; Molecular Structure; Particle Size; Phenylalanine; Spectrum Analysis, Raman; Stereoisomerism; Tyrosine; Vibration | 2021 |
Heat Capacities of l-Histidine, l-Phenylalanine, l-Proline, l-Tryptophan and l-Tyrosine.
Topics: Histidine; Hot Temperature; Phenylalanine; Proline; Thermodynamics; Tryptophan; Tyrosine | 2021 |
The Novel Interplay between Commensal Gut Bacteria and Metabolites in Diet-Induced Hyperlipidemic Rats Treated with Simvastatin.
Topics: Animals; Bacteria; Diet; Feces; Linoleic Acids; Metabolomics; Phenylalanine; Rats; RNA, Ribosomal, 16S; Simvastatin; Tandem Mass Spectrometry; Tyrosine | 2022 |
Dopamine Precursor Depletion in Healthy Volunteers Impairs Processing of Duration but Not Temporal Order.
Topics: Cross-Over Studies; Dopamine; Double-Blind Method; Healthy Volunteers; Humans; Phenylalanine; Time Perception; Tyrosine | 2021 |
Fast label-free identification of bacteria by synchronous fluorescence of amino acids.
Topics: Amino Acids; Bacteria; Bacterial Typing Techniques; Calibration; Escherichia coli; Fluorescence; Phenylalanine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2021 |
Biosynthesis of the Fusarium Mycotoxin (-)-Sambutoxin.
Topics: Alkaloids; Fusarium; Molecular Structure; Mycotoxins; Oxidation-Reduction; Phenylalanine; Pyridines; Tyrosine | 2021 |
Serum concentrations of phenylalanine and tyrosine isomers in patients with acute coronary syndrome.
Topics: Acute Coronary Syndrome; Humans; Phenylalanine; Tyrosine | 2021 |
Dietary tryptophan, tyrosine, and phenylalanine depletion induce reduced food intake and behavioral alterations in mice.
Topics: Animals; Diet; Eating; Mice; Phenylalanine; Tryptophan; Tyrosine | 2022 |
Beneficial Effects of Slow-Release Large Neutral Amino Acids after a Phenylalanine Oral Load in Patients with Phenylketonuria.
Topics: Adolescent; Adult; Amino Acids; Amino Acids, Neutral; Diet; Dietary Supplements; Female; Humans; Italy; Male; Micronutrients; Phenylalanine; Phenylketonurias; Tyrosine; Young Adult | 2021 |
A highly accurate mass spectrometry method for the quantification of phenylalanine and tyrosine on dried blood spots: Combination of liquid chromatography, phenylalanine/tyrosine-free blood calibrators and multi-point/dynamic calibration.
Topics: Chromatography, Liquid; Dried Blood Spot Testing; Humans; Phenylalanine; Tandem Mass Spectrometry; Tyrosine | 2022 |
Essential roles of buried phenylalanine in the structural stability of thioredoxin from a psychrophilic Arctic bacterium Sphingomonas sp.
Topics: Amino Acid Sequence; Insulin; Kinetics; Models, Molecular; Mutation; Phenylalanine; Protein Conformation; Protein Stability; Protein Unfolding; Sphingomonas; Thioredoxins; Tyrosine | 2021 |
The effect of casein glycomacropeptide versus free synthetic amino acids for early treatment of phenylketonuria in a mice model.
Topics: Amino Acids; Animals; Bone and Bones; Bone Density; Brain; Caseins; Dietary Supplements; Disease Models, Animal; Female; Maze Learning; Mice; Mice, Inbred C57BL; Peptide Fragments; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Serotonin; Tyrosine | 2022 |
Synthesis of 2,6-Dimethyltyrosine-Like Amino Acids through Pinacolinamide-Enabled C-H Dimethylation of 4-Dibenzylamino Phenylalanine.
Topics: Amino Acids; Phenylalanine; Tyrosine | 2022 |
Comprehensively understanding metabolic pathways of protein during the anaerobic digestion of waste activated sludge.
Topics: Acetyl Coenzyme A; Alanine; Amino Acids; Anaerobiosis; Arginine; Glutamates; Glycine; Histidine; Leucine; Lysine; Metabolic Networks and Pathways; Methionine; Phenylalanine; Pyruvic Acid; Serine; Sewage; Threonine; Tyrosine | 2022 |
Neural correlates of working memory and its association with metabolic parameters in early-treated adults with phenylketonuria.
Topics: Adult; Cross-Sectional Studies; Humans; Memory, Short-Term; Phenylalanine; Phenylketonurias; Retrospective Studies; Tyrosine | 2022 |
Metabolomics integrated with transcriptomics reveals the changes during developmental stages in Shiraia bambusicola.
Topics: Ascomycota; Coumarins; Metabolomics; Phenylalanine; Quinones; Terpenes; Transcriptome; Tryptophan; Tyrosine; Ubiquinone | 2022 |
Brain Functional Network and Amino Acid Metabolism Association in Females with Subclinical Depression.
Topics: Brain; Depression; Electroencephalography; Female; Humans; Phenylalanine; Tryptophan; Tyrosine | 2022 |
Metabolomic Workflow for the Accurate and High-Throughput Exploration of the Pathways of Tryptophan, Tyrosine, Phenylalanine, and Branched-Chain Amino Acids in Human Biofluids.
Topics: Amino Acids, Branched-Chain; Chromatography, High Pressure Liquid; Humans; Phenylalanine; Tandem Mass Spectrometry; Tryptophan; Tyrosine; Workflow | 2022 |
Non-Invasive, Topical Sampling of Potential, Low-Molecular Weight, Skin Cancer Biomarkers: A Study on Healthy Volunteers.
Topics: Biomarkers; Biomarkers, Tumor; Healthy Volunteers; Humans; Kynurenine; Molecular Weight; Phenylalanine; Skin Neoplasms; Tryptophan; Tyrosine | 2022 |
M379A Mutant Tyrosine Phenol-lyase from Citrobacter freundii Has Altered Conformational Dynamics.
Topics: Catalytic Domain; Citrobacter freundii; Kinetics; Methionine; Mutagenesis, Site-Directed; Phenylalanine; Tyrosine; Tyrosine Phenol-Lyase | 2022 |
Muscle Protein Synthesis after Protein Administration in Critical Illness.
Topics: Adult; Aged; Amino Acids; Critical Illness; Dietary Proteins; Female; Humans; Leucine; Male; Middle Aged; Milk Proteins; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Tyrosine | 2022 |
Insight into the differences in the toxicity mechanisms of dinotefuran enantiomers in zebrafish by UPLC-Q/TOF-MS.
Topics: Animals; Arginine; Biomarkers; Chromatography, High Pressure Liquid; Glycerophospholipids; Guanidines; Insecticides; Metabolome; Metabolomics; Neonicotinoids; Nitro Compounds; Phenylalanine; Proline; Stereoisomerism; Tryptophan; Tyrosine; Vitamin A; Zebrafish | 2022 |
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
Topics: Biological Factors; Carcinoma, Hepatocellular; COVID-19; Deep Learning; Gonadotropin-Releasing Hormone; Humans; Isoleucine; Leucine; Liver Neoplasms; Lysine; Mitogen-Activated Protein Kinases; Phenylalanine; Tryptophan; Tyrosine; Valine | 2022 |
On Aromaticity of the Aromatic α-Amino Acids and Tuning of the NICS Indices to Find the Aromaticity Order.
Topics: Amino Acids; Amino Acids, Aromatic; Phenylalanine; Tryptophan; Tyrosine | 2022 |
Isolation and characterization of novel antihypertensive bioactive peptides from brassica napus and angiotensin-converting enzyme (ace) inhibition potential.
Topics: Alanine; Angiotensins; Antihypertensive Agents; Arginine; Brassica napus; Cysteine; Glutamine; Glycine; Histidine; Isoleucine; Leucine; Lysine; Methionine; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Proline; Tandem Mass Spectrometry; Threonine; Tyrosine; Valine | 2022 |
Study on antibody adsorption and elution performance of carboxyl and hydrophobic groups on mixed-mode ligands.
Topics: Adsorption; Glutamates; Glutamine; Humans; Hydrophobic and Hydrophilic Interactions; Immunoglobulin G; Ligands; Phenylalanine; Tyrosine | 2022 |
Tetrahydrobiopterin modulates the behavioral neuroinflammatory response to an LPS challenge in mice.
Topics: Animals; Biopterins; Cytokines; Inflammation; Lipopolysaccharides; Mice; Phenylalanine; Tyrosine | 2022 |
Transcriptomic and proteomic analyses reveal the common and unique pathway(s) underlying different skin colors of leopard coral grouper (Plectropomus leopardus).
Topics: Animals; Anthozoa; Bass; Fatty Acids; Humans; Phenylalanine; Proteomics; Skin Pigmentation; Transcriptome; Tyrosine | 2022 |
Metabolomic Characterization of Acute Ischemic Stroke Facilitates Metabolomic Biomarker Discovery.
Topics: Argininosuccinic Acid; Biomarkers; Glucosamine; Glycerophospholipids; Humans; Ischemic Stroke; Lysine; Metabolomics; Oxygen; Phenylalanine; RNA, Transfer; Stroke; Tryptophan; Tyrosine | 2022 |
The first step into phenolic metabolism in the hornwort Anthoceros agrestis: molecular and biochemical characterization of two phenylalanine ammonia-lyase isoforms.
Topics: Anthocerotophyta; Histidine; Phenols; Phenylalanine; Phenylalanine Ammonia-Lyase; Phylogeny; Protein Isoforms; Tyrosine | 2022 |
Micro-Raman spectroscopy study of blood samples from myocardial infarction patients.
Topics: Humans; Inflammation; Myocardial Infarction; Phenylalanine; Spectrum Analysis, Raman; Tyrosine | 2022 |
Population-based metagenomics analysis reveals altered gut microbiome in sarcopenia: data from the Xiangya Sarcopenia Study.
Topics: alpha-Linolenic Acid; Bacteroides; Clostridiaceae; Clostridiales; Desulfovibrio; Female; Furaldehyde; Gastrointestinal Microbiome; Humans; Middle Aged; Phenylalanine; RNA, Ribosomal, 16S; Sarcopenia; Staurosporine; Tryptophan; Tyrosine | 2022 |
Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa.
Topics: Chromatography, Liquid; Epidermolysis Bullosa Dystrophica; Fibrosis; Glutamates; Glutamine; Humans; Inflammation; Kynurenine; Malnutrition; Phenylalanine; Succinates; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
New insights into the effect of bisphenol AF exposure on maternal mammary glands at various stages of gestation in mice.
Topics: Amino Acids; Ammonia; Animals; Benzhydryl Compounds; Female; Fluorocarbons; Mice; Ornithine; Phenylalanine; Pregnancy; Proline; RNA, Messenger; Threonine; Tyrosine; Valine | 2022 |
Phenylalanine suppresses cell death caused by loss of fumarylacetoacetate hydrolase in Arabidopsis.
Topics: Ammonia-Lyases; Animals; Arabidopsis; Cell Death; Chlorophyll; Hydrolases; Phenylalanine; Tyrosine; Tyrosine Transaminase | 2022 |
Rational engineering of a synthetic insect-bacterial mutualism.
Topics: Amino Acids, Aromatic; Animals; Bacteria; Insecta; Phenylalanine; Phylogeny; Symbiosis; Tyrosine; Weevils | 2022 |
Establishment of an early diagnosis model of colon cancerous bowel obstruction based on 1H NMR.
Topics: 3-Hydroxyanthranilic Acid; Biomarkers; Colon; Early Diagnosis; Humans; Kynurenic Acid; Metabolome; Metabolomics; Phenylalanine; Proton Magnetic Resonance Spectroscopy; Tryptophan; Tyrosine | 2022 |
Stepwise metabolic engineering of Corynebacterium glutamicum for the production of phenylalanine.
Topics: Corynebacterium glutamicum; Escherichia coli; Metabolic Engineering; Phenylalanine; Tyrosine | 2023 |
Thermodynamics of iron, tetrahydrobiopterin, and phenylalanine binding to phenylalanine hydroxylase from Chromobacterium violaceum.
Topics: Biopterins; Chromobacterium; Ferrous Compounds; Iron; Kinetics; Metalloproteins; Phenylalanine; Phenylalanine Hydroxylase; Pterins; Thermodynamics; Tyrosine | 2022 |
Impact of dietary supplementation with N-carbamoyl-aspartic acid on serum metabolites and intestinal microflora of sows.
Topics: Animal Feed; Animals; Arginine; Aspartic Acid; Birth Weight; Colostrum; Diet; Dietary Supplements; Female; Gastrointestinal Microbiome; Lactation; Phenylalanine; Pregnancy; Proline; Swine; Tyrosine | 2023 |
Urine metabolomics analysis of sleep quality in deep-underground miners: A pilot study.
Topics: Glutamine; Humans; Neurotransmitter Agents; Phenylalanine; Pilot Projects; Sleep Quality; Tyrosine | 2022 |
The combination of microbiome and metabolome to analyze the cross-cooperation mechanism of
Topics: Alanine; Animals; Echinacea; Fatty Acids, Volatile; Gastrointestinal Microbiome; Glycine; Glycosphingolipids; Humans; Leucine; Metabolome; Mice; Microbiota; Ornithine; Phenylalanine; Polysaccharides; Porphyrins; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Using Metabolomics to Identify the Exposure and Functional Biomarkers of Ginger.
Topics: Animals; Biomarkers; Chromatography, Liquid; Humans; Metabolome; Metabolomics; Mice; Phenylalanine; Purines; Tandem Mass Spectrometry; Tryptophan; Tyrosine; Zingiber officinale | 2022 |
Structural basis for product specificities of MLL family methyltransferases.
Topics: Fluorine; Histone-Lysine N-Methyltransferase; Histones; Humans; Leukemia; Lysine; Methyltransferases; Myeloid-Lymphoid Leukemia Protein; Phenylalanine; Tyrosine | 2022 |
Protein engineering for feedback resistance in 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Amino Acids, Aromatic; Carbon; Escherichia coli; Feedback; Isoenzymes; Phenylalanine; Phosphates; Protein Engineering; Tryptophan; Tyrosine | 2022 |
Volatile Dimethyl Disulfide from Guava Plants Regulate Developmental Performance of Asian Citrus Psyllid through Activation of Defense Responses in Neighboring Orange Plants.
Topics: Animals; Catechol Oxidase; Citrus; Citrus sinensis; Disulfides; Hemiptera; Peroxidases; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Diseases; Polyphenols; Protons; Psidium; Salicylic Acid; Sulfur; Transferases; Tryptophan; Tyrosine | 2022 |
Unraveling the Role of the Tyrosine Tetrad from the Binding Site of the Epigenetic Writer MLL3 in the Catalytic Mechanism and Methylation Multiplicity.
Topics: Alanine; Binding Sites; Epigenesis, Genetic; Histone-Lysine N-Methyltransferase; Histones; Lysine; Methylation; Phenylalanine; Tyrosine; Water | 2022 |
[Determination of free amino acids in Eriocheir sinensis by ultra-high performance liquid chromatography-high resolution mass spectrometry].
Topics: Acetonitriles; Alanine; Amino Acids; Animals; Arginine; Aspartic Acid; Brachyura; Chromatography, High Pressure Liquid; Cystine; Formates; Glutamates; Glycine; Histidine; Isoleucine; Leucine; Lysine; Mass Spectrometry; Methionine; Perchlorates; Phenylalanine; Polypropylenes; Proline; Serine; Solvents; Threonine; Tyrosine; Valine; Water | 2022 |
[Mechanism of Cordyceps militaris against non-small cell lung cancer: based on serum metabolomics].
Topics: Alanine; Animals; Arginine; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cordyceps; Glutamic Acid; Glutamine; Glyoxylates; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Nitrogen; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine | 2022 |
[Cell metabolomics study of ginkgo flavone aglycone combined with doxorubicin against liver cancer in synergy].
Topics: Arginine; beta-Alanine; Doxorubicin; Flavones; Ginkgo biloba; Glutathione; Humans; Isoleucine; Leucine; Liver Neoplasms; Metabolomics; Phenylalanine; Proline; Tandem Mass Spectrometry; Tyrosine; Valine | 2022 |
Determinants of tyrosinaemia during nitisinone therapy in alkaptonuria.
Topics: Alkaptonuria; Brain Diseases, Metabolic, Inborn; Cyclohexanones; Homogentisic Acid; Humans; Nitrobenzoates; Phenylalanine; Phenylpropionates; Tyrosine; Tyrosinemias | 2022 |
Intestinal metabolomics of juvenile lenok (Brachymystax lenok) in response to heat stress.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Acetylcarnitine; Animals; Aspartic Acid; Erucic Acids; Glucose; Glutamine; Heat-Shock Response; Histidine; Intestines; Lactates; Leucine; Methionine; Oxylipins; Palmitoylcarnitine; Phenylalanine; Phosphatidylcholines; Phosphorylcholine; Proline; Salmonidae; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
Mutations of tyrosine 467 in the human norepinephrine transporter attenuate HIV-1 Tat-induced inhibition of dopamine transport while retaining physiological function.
Topics: Animals; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Fluoxetine; Histidine; HIV-1; Humans; Mutation; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Phenylalanine; Rats; Symporters; Trans-Activators; Tyrosine | 2022 |
Metabolite variations in the sera of HIV+ patients after an oral administration of effervescent glutamine and in comparison to non-HIV individuals by NMR.
Topics: Administration, Oral; Glutamine; HIV Infections; Humans; Phenylalanine; Pilot Projects; Tyrosine | 2023 |
Crystal structures of FNIP/FGxxFN motif-containing leucine-rich repeat proteins.
Topics: Amino Acid Sequence; Asparagine; Dictyostelium; Histidine; Isoleucine; Leucine; Leucine-Rich Repeat Proteins; Phenylalanine; Tryptophan; Tyrosine | 2022 |
Exploring the nephrotoxicity of sulfur-containing derivatives in sulfur-fumigated Panacis Quinquefolii Radix based on chemical profiling and untargeted metabolomics.
Topics: Animals; Chromatography, High Pressure Liquid; Drugs, Chinese Herbal; Fumigation; Metabolomics; Mice; Molecular Docking Simulation; Phenylalanine; Sulfur; Tryptophan; Tyrosine | 2023 |
Endogenous benzoic acid interferes with the signatures of amino acids and thiol compounds through perturbing N-methyltransferase, glutamate-cysteine ligase, and glutathione S-transferase activity in dairy products.
Topics: Amino Acids; Animals; Benzoic Acid; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Glutathione Transferase; Goats; Histidine; Methyltransferases; Milk; Phenylalanine; Sulfhydryl Compounds; Tyrosine | 2022 |
Unsupervised recognition of components from the interaction of BSA with Fe cluster in different conditions utilizing 2D fluorescence spectroscopy.
Topics: Phenylalanine; Serum Albumin, Bovine; Spectrometry, Fluorescence; Tryptophan; Tyrosine | 2022 |
De novo full length transcriptome analysis and gene expression profiling to identify genes involved in phenylethanol glycosides biosynthesis in Cistanche tubulosa.
Topics: Cistanche; Gene Expression Profiling; Glycosides; Phenylalanine; Phenylethyl Alcohol; Tyrosine | 2022 |
Gut microbiome and metabolic activity in type 1 diabetes: An analysis based on the presence of GADA.
Topics: Antibodies; Diabetes Mellitus, Type 1; Gastrointestinal Microbiome; Glutamate Decarboxylase; Humans; Phenylalanine; RNA, Ribosomal, 16S; Tryptophan; Tyrosine | 2022 |
Role of phenylalanine/tyrosine ammonia lyase and anthocyanidin synthase enzymes for anthocyanin biosynthesis in developing Solanum melongena L. genotypes.
Topics: Anthocyanins; Gene Expression Regulation, Plant; Genotype; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Proteins; Solanum melongena; Tyrosine | 2022 |
Metabolomics Profiling of Nephrotic Syndrome towards Biomarker Discovery.
Topics: Arginine; Biomarkers; Humans; Lysine; Metabolome; Metabolomics; Nephrotic Syndrome; Phenylalanine; Proline; Threonine; Tryptophan; Tyrosine | 2022 |
Benincasa hispida extracts positively regulated high salt-induced hypertension in Dahl salt-sensitive rats: Impact on biochemical profile and metabolic patterns.
Topics: Alanine; Amino Acids; Animals; Antihypertensive Agents; Antioxidants; Aspartic Acid; Cucurbitaceae; Glycine; Hypertension; Phenylalanine; Plant Extracts; Rats; Rats, Inbred Dahl; Renal Insufficiency; Serine; Sodium Chloride; Sodium Chloride, Dietary; Threonine; Tyrosine | 2022 |
Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation.
Topics: alpha-Synuclein; Animals; Humans; Mice; Mice, Transgenic; Mutation; Neurotoxicity Syndromes; Phenylalanine; Serine; Tyrosine | 2022 |
The
Topics: Animals; Clostridium; Inflammation; Kupffer Cells; Lipopolysaccharides; Liver Cirrhosis, Biliary; Mice; Phenylalanine; Sulfates; Tyrosine | 2022 |
Metabolic pathway analysis of hyperuricaemia patients with hyperlipidaemia based on high-throughput mass spectrometry: a case‒control study.
Topics: Alanine; Aspartic Acid; Biomarkers; Case-Control Studies; Glycine; Humans; Hyperlipidemias; Hyperuricemia; Linoleic Acid; Mass Spectrometry; Metabolic Diseases; Metabolic Networks and Pathways; Phenylalanine; Serine; Threonine; Tryptophan; Tyrosine | 2022 |
Identification of region-specific amino acid signatures for doxorubicin-induced chemo brain.
Topics: Amino Acids; Animals; Brain; Doxorubicin; Humans; Methionine; Mice; Phenylalanine; Quality of Life; Tandem Mass Spectrometry; Tyrosine | 2023 |
Interference-free quantitation of aromatic amino acids in two complex systems by three-way calibration with ultraviolet-visible spectrophotometer: Exploration of trilinear decomposition of spectrum-pH data.
Topics: Algorithms; Amino Acids, Aromatic; Calibration; Chromatography, High Pressure Liquid; Hydrogen-Ion Concentration; Phenylalanine; Tryptophan; Tyrosine | 2023 |
UPLC/Q-TOF-MS-based metabolomics evaluate the efficacy of oroxylin A against postmenopausal osteoporosis.
Topics: Animals; Biomarkers; Female; Humans; Mass Spectrometry; Metabolomics; Mice; Osteoporosis, Postmenopausal; Phenylalanine; Tryptophan; Tyrosine | 2023 |
Metabolomics profiling of seminal plasma in obesity-induced asthenozoospermia.
Topics: Aconitic Acid; Alanine; Asthenozoospermia; Citrulline; Glucose; Glutamic Acid; Glycine; Humans; Leucine; Lysine; Male; Metabolomics; Phenylalanine; Proline; Semen; Serine; Succinic Acid; Threonine; Tyrosine; Valine | 2023 |
Self-assembly of a dimeric avidin into unique higher-order oligomers.
Topics: Amino Acid Sequence; Avidin; Biotin; Phenylalanine; Tyrosine | 2023 |
Competitive, multi-objective, and compartmented Flux Balance Analysis for addressing tissue-specific inborn errors of metabolism.
Topics: Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 2023 |
Efficient biosynthesis of resveratrol via combining phenylalanine and tyrosine pathways in Saccharomyces cerevisiae.
Topics: Metabolic Engineering; Phenylalanine; Phenylalanine Ammonia-Lyase; Resveratrol; Saccharomyces cerevisiae; Tyrosine | 2023 |
Rational design, production and in vitro analysis of photoxenoproteins.
Topics: Amino Acids; Phenylalanine; Proteins; Tyrosine | 2023 |
Higher dietary intake of aromatic amino acids was associated with lower risk of cardiovascular disease mortality in adult participants in NHANES III.
Topics: Adult; Amino Acids; Amino Acids, Aromatic; Cardiovascular Diseases; Cohort Studies; Eating; Humans; Nutrition Surveys; Phenylalanine; Tryptophan; Tyrosine; United States | 2023 |
Metabolomics profile of plasma in acute diquat-poisoned patients using gas chromatography-mass spectrometry.
Topics: Biomarkers; Diquat; Gas Chromatography-Mass Spectrometry; Humans; Metabolomics; Phenylalanine; Poisons; Taurine; Tyrosine | 2023 |
Whole-Body and Forearm Muscle Protein Metabolism in Patients With Acromegaly Before and After Treatment.
Topics: Acromegaly; Body Composition; Energy Metabolism; Forearm; Humans; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Tyrosine | 2023 |
Spectroscopic Investigation of the Metal Coordination of the Aromatic Amino Acids with Zinc and Cadmium.
Topics: Amino Acids, Aromatic; Benzene; Cadmium; Nitrogen; Oxygen; Phenylalanine; Spectrophotometry, Infrared; Tryptophan; Tyrosine; Zinc | 2023 |
Nuclear ATR lysine-tyrosylation protects against heart failure by activating DNA damage response.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; DNA Damage; Heart Failure; Lysine; Mice; Phenylalanine; Tyrosine; Tyrosine-tRNA Ligase | 2023 |
Biosynthesis of Betalains Elicited by Methyl Jasmonate in Two Species of Alternanthera Genus: Antagonistic Regulations Result in Increase of Pigments.
Topics: Amaranthaceae; Antioxidants; Betalains; Flavonoids; Gene Expression Regulation, Plant; Metabolic Networks and Pathways; Phenols; Phenylalanine; Pigments, Biological; Tyrosine | 2023 |
Developmental delay and non-phenylketonuria (PKU) hyperphenylalaninemia in DNAJC12 deficiency: Case and approach.
Topics: Autism Spectrum Disorder; Biopterins; Homovanillic Acid; Humans; Infant, Newborn; Male; Movement Disorders; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Tyrosine | 2023 |
Engineering a Pseudomonas taiwanensis 4-coumarate platform for production of para-hydroxy aromatics with high yield and specificity.
Topics: Cinnamates; Glycerol; Metabolic Engineering; Phenylalanine; Tyrosine | 2023 |
Metabolic engineering of the shikimate pathway in Amycolatopsis strains for optimized glycopeptide antibiotic production.
Topics: Actinomycetales; Amycolatopsis; Anti-Bacterial Agents; Glycopeptides; Metabolic Engineering; Phenylalanine; Tyrosine | 2023 |
Dynamic changes of serum metabolite profiling in septic mice based on high performance liquid chromatography of quadrupole time of flight mass spectrometry analysis.
Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Male; Metabolomics; Mice; Phenylalanine; Sepsis; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2023 |
Difference and clinical value of metabolites in plasma and feces of patients with alcohol-related liver cirrhosis.
Topics: Albumins; Bile Acids and Salts; Bilirubin; Feces; Humans; Liver Cirrhosis, Alcoholic; Methionine; Phenylalanine; Tyrosine | 2023 |
Ultraviolet Resonance Raman Spectra of Serum Albumins.
Topics: Humans; Phenylalanine; Serum Albumin; Serum Albumin, Bovine; Spectrum Analysis, Raman; Tryptophan; Tyrosine; Vibration | 2023 |
Metabolomics reveals serum metabolic signatures in H-type hypertension based on mass spectrometry multi-platform.
Topics: Arginine; Biomarkers; Humans; Hypertension; Mass Spectrometry; Metabolomics; Phenylalanine; Tyrosine | 2023 |
The effect of inflammation, SARS-CoV-2 infection, age and mental health on serotonin, and kynurenine and catecholamine pathway metabolites.
Topics: COVID-19; Cross-Sectional Studies; Dopamine; Humans; Inflammation; Kynurenine; Mental Health; Phenylalanine; SARS-CoV-2; Serotonin; Tryptophan; Tyrosine | 2023 |
Metabolic engineering strategies for naringenin production enhancement in Streptomyces albidoflavus J1074.
Topics: Cerulenin; Flavanones; Industrial Microbiology; Metabolic Engineering; Phenylalanine; Streptomyces; Tyrosine | 2023 |
Quantitation of phenylalanine and tyrosine from dried Blood/Plasma spots with impregnated stable isotope internal standards (SIIS) by FIA-SRM.
Topics: Dried Blood Spot Testing; Flow Injection Analysis; Humans; Infant, Newborn; Isotopes; Phenylalanine; Solvents; Tyrosine | 2023 |
Ability of Latilactobacillus curvatus FAM25164 to produce tryptamine: Identification of a novel tryptophan decarboxylase.
Topics: Amino Acids; Aromatic-L-Amino-Acid Decarboxylases; Escherichia coli; Lactobacillus; Levodopa; Phenylalanine; Tryptamines; Tyrosine | 2023 |
Free-Energy Landscape and Rate Estimation of the Aromatic Ring Flips in Basic Pancreatic Trypsin Inhibitors Using Metadynamics.
Topics: Aprotinin; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation; Trypsin Inhibitors; Tyrosine | 2023 |
Exploring the Substrate Switch Motif of Aromatic Ammonia Lyases.
Topics: Amino Acids; Ammonia-Lyases; Lyases; Phenylalanine; Phenylalanine Ammonia-Lyase; Substrate Specificity; Tyrosine | 2023 |
Investigation of the Impact of L-Phenylalanine and L-Tyrosine Pre-Treatment on the Uptake of 4-Borono-L-Phenylalanine in Cancerous and Normal Cells Using an Analytical Approach Based on SC-ICP-MS.
Topics: Animals; Boron; Boron Compounds; Boron Neutron Capture Therapy; Cricetinae; Humans; Phenylalanine; Spectrum Analysis; Tyrosine | 2023 |
The effects of phenylalanine and tyrosine levels on dopamine production in rat PC12 cells. Implications for treatment of phenylketonuria, tyrosinemia type 1 and comorbid neurodevelopmental disorders.
Topics: Animals; Dopamine; Neurodevelopmental Disorders; PC12 Cells; Phenylalanine; Phenylketonurias; Proteomics; Rats; Tyrosine; Tyrosine 3-Monooxygenase; Tyrosinemias | 2023 |
Effect of woohwangchungsimwon and donepezil co-treatment on cognitive function and serum metabolic profiles in a scopolamine-induced model of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Donepezil; Humans; Metabolome; Methionine; Mice; Mice, Inbred ICR; Neuroblastoma; Phenylalanine; Reactive Oxygen Species; Scopolamine Derivatives; Tyrosine | 2024 |
Coordinated regulation of the entry and exit steps of aromatic amino acid biosynthesis supports the dual lignin pathway in grasses.
Topics: Amino Acids, Aromatic; Arabidopsis; Lignin; Phenylalanine; Plants; Poaceae; Tyrosine | 2023 |
Synthesis, kinetic studies and pharmacological evaluation of mutual azo prodrugs of 5-aminosalicylic acid for colon-specific drug delivery in inflammatory bowel disease.
Topics: Aminosalicylic Acids; Animals; Arthritis; Colitis; Colon; Female; Inflammatory Bowel Diseases; Male; Peroxidase; Prodrugs; Rats; Rats, Wistar; Ulcer | 2009 |