phenylalanine has been researched along with telotristat in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (83.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Diacou, A; Gershon, MD; Jhaver, KG; Li, Z; Margolis, KG; Oravecz, T; Stevanovic, K; Yang, QM; Zambrowicz, B | 1 |
| Banks, P; Bergsland, E; Fleming, D; Frazier, K; Freiman, J; Jackson, J; Kulke, MH; Kvols, L; Lapuerta, P; Law, L; O'Dorisio, T; Phan, A; Sands, A; Yao, JC; Zambrowicz, B | 1 |
| Banks, P; Caplin, M; Fleming, D; Hörsch, D; Lapuerta, P; Pavel, M; Ramage, J; Sands, A; Seufferlein, T; Valle, J; Wiedenmann, B; Zambrowicz, B | 1 |
| Khan, WI; Kim, JJ; Terc, JD; Wang, H; Yang, QM; Zambrowicz, B | 1 |
| Auguste, P; Boehm, KA; Gelhorn, HL; Jackson, J; Jackson, S; Kostelec, J; Kulke, MH; Lapuerta, P; Law, L; O'Dorisio, T; Yang, QM | 1 |
| Alonso-Gordoa, T; Grande, E; Martínez-Sáez, O; Molina-Cerrillo, J | 1 |
| Barriuso, J; Hubner, RA; Lamarca, A; McNamara, MG; Valle, JW | 1 |
| Markham, A | 1 |
| Ratner, M | 1 |
| Rendell, MS | 1 |
| Calzo, FL; Colao, A; Faggiano, A; Fanciulli, G; Grossrubatscher, E; Isidori, A; Ruggeri, RM; Wood, TD | 1 |
| Balakrishna, P; George, S; Hatoum, H; Mukherjee, S | 1 |
5 review(s) available for phenylalanine and telotristat
| Article | Year |
|---|---|
Inhibition of Peripheral Synthesis of Serotonin as a New Target in Neuroendocrine Tumors.
Topics: Carcinoid Tumor; Clinical Trials as Topic; Drug Resistance, Neoplasm; Humans; Phenylalanine; Pyrimidines; Serotonin; Somatostatin | 2016 |
Telotristat ethyl: a new option for the management of carcinoid syndrome.
Topics: Animals; Carcinoid Tumor; Clinical Trials as Topic; Humans; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Somatostatin; Tryptophan Hydroxylase | 2016 |
The journey from gene knockout to clinical medicine: telotristat and sotagliflozin.
Topics: Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Gene Knockout Techniques; Glucose; Glycosides; Humans; Hypoglycemic Agents; Phenylalanine; Pyrimidines; Serotonin; Sodium-Glucose Transporter 1; Sodium-Glucose Transporter 2; Tryptophan Hydroxylase | 2019 |
Serotonin pathway in carcinoid syndrome: Clinical, diagnostic, prognostic and therapeutic implications.
Topics: Humans; Malignant Carcinoid Syndrome; Phenylalanine; Pyrimidines; Serotonin; Signal Transduction; Tryptophan Hydroxylase | 2020 |
Serotonin Pathway in Cancer.
Topics: Antineoplastic Agents, Hormonal; Carcinoma, Neuroendocrine; Cell Movement; Cell Proliferation; Cholangiocarcinoma; Gene Expression Regulation, Neoplastic; Humans; Molecular Targeted Therapy; Neovascularization, Pathologic; Octreotide; Phenylalanine; Pyrimidines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Signal Transduction; Tryptophan Hydroxylase; Tumor Cells, Cultured | 2021 |
3 trial(s) available for phenylalanine and telotristat
| Article | Year |
|---|---|
Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Diarrhea; Female; Gastrointestinal Agents; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Octreotide; Phenylalanine; Pyrimidines; Serotonin Antagonists; Treatment Outcome | 2014 |
Telotristat etiprate for carcinoid syndrome: a single-arm, multicenter trial.
Topics: Abdominal Pain; Adult; Aged; Aged, 80 and over; Female; Flushing; Gastrointestinal Transit; Humans; Hydroxyindoleacetic Acid; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome | 2015 |
Patient-reported Symptom Experiences in Patients With Carcinoid Syndrome After Participation in a Study of Telotristat Etiprate: A Qualitative Interview Approach.
Topics: Aged; Antineoplastic Agents; Diarrhea; Female; Humans; Interviews as Topic; Male; Malignant Carcinoid Syndrome; Middle Aged; Phenylalanine; Pyrimidines; Treatment Outcome | 2016 |
4 other study(ies) available for phenylalanine and telotristat
| Article | Year |
|---|---|
Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine.
Topics: Animals; Brain; Colitis; Cytokines; Down-Regulation; Enzyme Inhibitors; Gastrointestinal Motility; Gene Expression; Intestinal Mucosa; Male; Mice, Inbred C57BL; Myenteric Plexus; Neurons; Phenylalanine; Pyrimidines; Serotonin; Severity of Illness Index; Trinitrobenzenesulfonic Acid; Tryptophan Hydroxylase | 2014 |
Blocking peripheral serotonin synthesis by telotristat etiprate (LX1032/LX1606) reduces severity of both chemical- and infection-induced intestinal inflammation.
Topics: Animals; Colon; Cytokines; Dextran Sulfate; Enterochromaffin Cells; Inflammatory Bowel Diseases; Mice; Mice, Inbred C57BL; Peroxidase; Phenylalanine; Pyrimidines; Serotonin; Serotonin Antagonists; Trichuriasis; Trichuris; Tryptophan Hydroxylase | 2015 |
Telotristat Ethyl: First Global Approval.
Topics: Animals; Diarrhea; Drug Approval; Drug Therapy, Combination; Humans; Malignant Carcinoid Syndrome; Neuroendocrine Tumors; Phenylalanine; Pyrimidines; Randomized Controlled Trials as Topic; Somatostatin; Tryptophan Hydroxylase; United States; United States Food and Drug Administration | 2017 |
Genomics pioneer gets its first drug.
Topics: Drug Industry; Genomics; Humans; Phenylalanine; Pyrimidines; Tryptophan Hydroxylase | 2017 |