phenylalanine and sirolimus

phenylalanine has been researched along with sirolimus in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's4 (30.77)29.6817
2010's3 (23.08)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Cheng, YR; Demain, AL; Fang, A1
Demain, AL; Fang, A1
Diez, C; Hoppe, J; Piper, HM; Schlüter, K; Simm, A1
Marsh, JD; Ritchie, RH; Schiebinger, RJ1
Proud, CG; Wang, L; Wang, X1
Buckle, AM; Fulton, KF; Jackson, SE1
Nandigama, R; Padmasekar, M; Sauer, H; Schlüter, KD; Wartenberg, M1
Al-Younes, H; Braun, PR; Gussmann, J; Klein, J; Meyer, TF; Schneider, E1
Chen, X; Duan, Y; Wu, H; Xu, Z; Zhang, W; Zhu, X1
Dickinson, JM; Drummond, MJ; Fry, CS; Gundermann, DM; Rasmussen, BB; Timmerman, KL; Volpi, E; Walker, DK1
Dong, X; Helmbrecht, A; Loor, JJ; Saremi, B; Wang, Z; Zhou, Z1
Chen, S; Chen, X; Dai, J; Shangguan, L; Xia, H; Yang, Q; Yang, S; Yao, L; Zhang, X1

Trials

1 trial(s) available for phenylalanine and sirolimus

ArticleYear
Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle.
    Metabolism: clinical and experimental, 2013, Volume: 62, Issue:1

    Topics: Absorption; Adult; Autophagy; Biopsy; Cross-Over Studies; Female; Humans; Immunoblotting; Kinetics; Male; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Phosphorylation; Proteins; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Young Adult

2013

Other Studies

12 other study(ies) available for phenylalanine and sirolimus

ArticleYear
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
Effect of amino acids on rapamycin biosynthesis by Streptomyces hygroscopicus.
    Applied microbiology and biotechnology, 1995, Volume: 43, Issue:6

    Topics: Amino Acids; Antifungal Agents; Culture Media; Lysine; Methionine; Phenylalanine; Pipecolic Acids; Polyenes; Quaternary Ammonium Compounds; Sirolimus; Streptomyces

1995
Exogenous shikimic acid stimulates rapamycin biosynthesis in Streptomyces hygroscopicus.
    Folia microbiologica, 1995, Volume: 40, Issue:6

    Topics: Immunosuppressive Agents; Phenylalanine; Polyenes; Shikimic Acid; Sirolimus; Streptomyces

1995
Activation of p70(S6) kinase by beta-adrenoceptor agonists on adult cardiomyocytes.
    Journal of molecular and cellular cardiology, 1998, Volume: 30, Issue:10

    Topics: Adrenergic beta-Agonists; Animals; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heart; Isoproterenol; Kinetics; Myocardium; Phenylalanine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Ribosomal Protein S6 Kinases; Sirolimus

1998
Bradykinin-stimulated protein synthesis by myocytes is dependent on the MAP kinase pathway and p70(S6K).
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Angiotensin II; Animals; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus

1999
Activation of mRNA translation in rat cardiac myocytes by insulin involves multiple rapamycin-sensitive steps.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:4

    Topics: Age Factors; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Flavonoids; Gene Expression Regulation, Enzymologic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Heart Ventricles; Hypoglycemic Agents; Immunosuppressive Agents; Insulin; Intracellular Signaling Peptides and Proteins; Methionine; Morpholines; Muscle Fibers, Skeletal; Myocardium; Peptide Elongation Factor 2; Peptide Initiation Factors; Phenylalanine; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Ribosomal Protein S6 Kinases; RNA, Messenger; Signal Transduction; Sirolimus; Sulfur Radioisotopes; Tritium

2000
Energetic and structural analysis of the role of tryptophan 59 in FKBP12.
    Biochemistry, 2003, Mar-04, Volume: 42, Issue:8

    Topics: Amino Acid Substitution; Crystallography, X-Ray; Humans; Hydrophobic and Hydrophilic Interactions; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Protein Binding; Protein Folding; Protein Isoforms; Recombinant Proteins; Sirolimus; Static Electricity; Structure-Activity Relationship; Tacrolimus Binding Protein 1A; Thermodynamics; Tryptophan

2003
The acute phase protein alpha2-macroglobulin induces rat ventricular cardiomyocyte hypertrophy via ERK1,2 and PI3-kinase/Akt pathways.
    Cardiovascular research, 2007, Jul-01, Volume: 75, Issue:1

    Topics: alpha-Macroglobulins; Androstadienes; Animals; Butadienes; Calcium; Cardiomegaly; Cells, Cultured; Chromones; Enzyme Activation; Immunohistochemistry; Male; Morpholines; Nitriles; Phenylalanine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Signal Transduction; Sirolimus; Wortmannin

2007
Competitive inhibition of amino acid uptake suppresses chlamydial growth: involvement of the chlamydial amino acid transporter BrnQ.
    Journal of bacteriology, 2008, Volume: 190, Issue:5

    Topics: Amino Acid Transport Systems; Amino Acids; Bacterial Proteins; Biological Transport; Cell Survival; Chlamydia; Chromatography, High Pressure Liquid; Cycloheximide; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Glycine; HeLa Cells; Humans; Isoleucine; Leucine; Methionine; Microscopy, Confocal; Microscopy, Electron, Transmission; Oligonucleotide Array Sequence Analysis; Phenylalanine; Reverse Transcriptase Polymerase Chain Reaction; Serine; Sirolimus; Threonine

2008
Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization.
    Biotechnology and bioengineering, 2010, Oct-15, Volume: 107, Issue:3

    Topics: Fermentation; Glucose; Lysine; Metabolic Networks and Pathways; Mutagenesis; Phenylalanine; Shikimic Acid; Sirolimus; Streptomyces; Tryptophan; Ultraviolet Rays

2010
Varying the ratio of Lys:Met while maintaining the ratios of Thr:Phe, Lys:Thr, Lys:His, and Lys:Val alters mammary cellular metabolites, mammalian target of rapamycin signaling, and gene transcription.
    Journal of dairy science, 2018, Volume: 101, Issue:2

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acids; Animals; Caseins; Cattle; Epithelial Cells; Female; Histidine; Lactation; Lysine; Mammary Glands, Animal; Milk; Milk Proteins; Phenylalanine; Phosphorylation; Protein Biosynthesis; Signal Transduction; Sirolimus; Threonine; TOR Serine-Threonine Kinases; Transcription, Genetic; Valine

2018
Rapamycin enhanced the production of 2-phenylethanol during whole-cell bioconversion by yeast.
    Applied microbiology and biotechnology, 2022, Volume: 106, Issue:19-20

    Topics: Perfume; Phenylalanine; Phenylethyl Alcohol; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sirolimus; Transcription Factors

2022