phenylalanine and phenylpyruvic acid

phenylalanine has been researched along with phenylpyruvic acid in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199040 (46.51)18.7374
1990's12 (13.95)18.2507
2000's10 (11.63)29.6817
2010's16 (18.60)24.3611
2020's8 (9.30)2.80

Authors

AuthorsStudies
Kadowaki, M; Mortimore, GE; Pösö, AR1
Behbehani, A; Langenbeck, U; Mench-Hoinowski, A1
Castillo, M; Garcia-Peregrin, E; Martinez-Cayuela, M; Zafra, MF1
Berry, A; Bhatnagar, RK; Hendry, AT; Jensen, RA1
Asano, Y; Cooper, AJ; Leung, LK1
Hummel, W; Kula, MR; Schütte, H1
Matalon, R; Michals, K1
Dwivedy, AK; Shah, SN1
Garcia-Morales, P; Hellerström, C; Herchuelz, A; Lebrun, P; Malaisse, WJ; Malaisse-Lagae, F; Saceda, M; Sener, A; Valverde, I; Welsh, M1
Langer, J; Panten, U1
Brusque, A; Wajner, M; Wannmacher, CM; Wyse, AT1
Godwin, BL; Ruthven, CR; Sandler, M1
Farré, C; Ramón, F; Vilaseca, MA1
Drechsel, H; Jung, G; Reissbrodt, R; Thieken, A; Winkelmann, G1
Csutora, P; Miseta, A; Sipos, K; Wheatley, DN1
Grenson, M; Iraqui, I; Urrestarazu, A; Vissers, S1
Breslow, R; Dong, SD; Fasella, E1
de Bont, JA; Nierop Groot, MN1
Bishop, JC; Cross, SD; Waddell, TG1
Battastini, AM; Berti, SL; Bonan, CD; da Silva, FL; Sarkis, JJ; Wannmacher, CM1
Amin, MR; Khan, RI; Mohammed, N; Onodera, R1
Cornelio, AR; de Souza Wyse, AT; Dutra-Filho, CS; Feksa, LR; Wajner, M; Wannmacher, CM1
Battastini, AM; Berti, SL; Bonan, CD; Kirst, IB; Oses, JP; Rücker, B; Sarkis, JJ1
Morais, MA; Piper, MD; Pronk, JT; Tai, SL; Vuralhan, Z1
DUNN, MS; EIDUSON, S2
BEN HAMIDA, F; LE MINOR, L1
ARMSTRONG, MD; LOW, NL1
CRANDALL, DI; GOTTESMAN, L; PIRRUNG, J1
JONXIS, JH1
BALL, E; DUNN, FW; IFLAND, PW; SHIVE, W1
TASHIAN, RE1
BISAZ, S1
LOWY, R; TREMOLIERES, J1
BOYLEN, JB; QUASTEL, JH1
FARQUHAR, JW; KANSAS, ET; TAIT, HP1
HOWELL, RK; LEE, M1
CULLEY, WJ; JOLLY, DH; MERTZ, ET; SAUNDERS, RN1
FARQUHAR, JW; RICHMOND, J; TAIT, HP1
BRIET, B; CHRISTIAENS, L; GAUDIER, B1
KRUPANIDHI, I; PUNEKAR, BD1
ZETTERSTROEM, R1
DAVID, JM1
ALLEN, RJ; WILSON, JL1
FONNUM, F; HAAVALDSEN, R; TANGEN, O1
VANDERHOEVEN, T; WOOLLEY, DW1
MILBURN, TR; WHITEHEAD, RG1
GAMBORG, OL; SIMPSON, FJ1
GJESSING, LR; HALVORSEN, S1
BINKLEY, SB; PREVIC, EP1
WU, WY1
KURAHASHI, K; TOMINO, S; YAMADA, M1
MCCORMICK, DB; WOODS, MN; YOUNG, SK1
EITINGER, L; KVAMME, E; SVENNEBY, G1
GERATZ, JD1
CHIBATA, I; SANO, R; TOSA, T1
CERUTTI, P; GUROFF, G1
Nicholls, IA; Svenson, J; Zheng, N1
Davies, JE; Eltis, LD; Mohn, WW; Navarro-Llorens, JM; Patrauchan, MA; Stewart, GR1
Cainelli, G; Engel, PC; Galletti, P; Giacomini, D; Gualandi, A; Paradisi, F1
Gallardo, E; Hidalgo, FJ; Navarro, JL; Zamora, R1
Song, Q; Tan, Q; Wei, D; Zhang, Y1
Choi, JO; Jung, SC; Lee, MH; Park, HY; Park, JW1
Dal Cin, V; de Vos, RC; Fernie, AR; Giovannoni, J; Haring, MA; Klee, HJ; McQuinn, R; Osorio, S; Schmelz, EA; Schuurink, RC; Smits-Kroon, MT; Taylor, MG; Tieman, DM; Tohge, T1
Daran, JM; Deshmuhk, A; Deshmukh, AT; Hanemaaijer, M; Pronk, JT; Romagnoli, G; Solis-Escalante, D; ten Pierick, A; Veiga, T; Wahl, A1
Bielawski, W; Szkop, M1
Cooper, BR; Dudareva, N; Gonda, I; Jannasch, AS; Lewinsohn, E; Maeda, H; Qian, Y; Rhodes, D; Widhalm, JR; Yoo, H1
Coban, HB; Demirci, A; Elias, RJ; Patterson, PH1
Averesch, NJ; Krömer, JO; Nunez-Bernal, D; Winter, G1
Kohno, Y; Matsumoto, A; Nakaya, H; Sanayama, Y; Shimojo, N1
Du, G; Hossain, GS; Hou, Y; Li, J; Liu, L; Shin, HD2
Fang, BS; Jiang, W1
Ávila, C; Cánovas, FM; de la Torre, F; El-Azaz, J1
Chen, J; Du, G; Hossain, GS; Hou, Y; Li, J; Liu, L; Shin, HD1
Ehsani-Zonouz, A; Jamshidi, S; Ziamajidi, N1
Dudareva, N; Guo, L; Lynch, JH; Morgan, JA; Qian, Y; Rhodes, D1
Beuel, T; Bloess, S; Dierks, T; Fischer von Mollard, G; Krüger, T; Sewald, N1
Bowman, ME; Dudareva, N; Garcia, AS; Guo, L; Huang, XQ; Louie, G; Lynch, JH; Maoz, I; Morgan, JA; Noel, JP; Qian, Y1
Gröger, H; Oike, K1
Asher, SA; Horne, WS; Jang, K1
Fukaya, M; Sato, Y; Suzuki, D; Suzuki, R; Yoshizawa, F1
Ashmore, C; Daly, A; Evans, S; MacDonald, A; Pinto, A1
Bai, Y; Cai, Y; Fan, TP; Xiong, T; Zheng, X1
Liu, Y; Westerhoff, HV1
Pająk, M; Pałka, K; Podsadni, K1

Reviews

2 review(s) available for phenylalanine and phenylpyruvic acid

ArticleYear
PHENYLKETONURIA IN PEDIATRIC PRACTICE.
    Clinical pediatrics, 1963, Volume: 2

    Topics: Child; Diet; Diet Therapy; Humans; Intelligence; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Scotland

1963
Protein Substitutes in PKU; Their Historical Evolution.
    Nutrients, 2021, Feb-02, Volume: 13, Issue:2

    Topics: Amino Acids; Animals; Caseins; Child, Preschool; Dietary Proteins; Female; History, 20th Century; History, 21st Century; Humans; Nutritional Requirements; Peptide Fragments; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Protein Hydrolysates; United Kingdom

2021

Other Studies

84 other study(ies) available for phenylalanine and phenylpyruvic acid

ArticleYear
Parallel control of hepatic proteolysis by phenylalanine and phenylpyruvate through independent inhibitory sites at the plasma membrane.
    The Journal of biological chemistry, 1992, Nov-05, Volume: 267, Issue:31

    Topics: Animals; Cell Membrane; Liver; Phenylalanine; Phenylpyruvic Acids; Proteins; Rats; Rats, Inbred Lew; Tyrosine

1992
A synopsis of the unconjugated acidic transamination metabolites of phenylalanine in phenylketonuria.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:1

    Topics: Adolescent; Child; Child, Preschool; Female; Humans; Kidney; Lactates; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids

1992
Effect of phenylalanine derivatives on the main regulatory enzymes of hepatic cholesterogenesis.
    Molecular and cellular biochemistry, 1991, Jun-26, Volume: 105, Issue:1

    Topics: Animals; Carbon Dioxide; Carboxy-Lyases; Chickens; Cholesterol; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Male; Mevalonic Acid; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Phosphorylation

1991
The biochemical basis for growth inhibition by L-phenylalanine in Neisseria gonorrhoeae.
    Molecular microbiology, 1989, Volume: 3, Issue:3

    Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Allosteric Regulation; Growth Inhibitors; Microbial Sensitivity Tests; Neisseria gonorrhoeae; Phenotype; Phenylalanine; Phenylpyruvic Acids; Transaminases; Tyrosine

1989
Enzymatic cycling assay for phenylpyruvate.
    Analytical biochemistry, 1989, Volume: 183, Issue:2

    Topics: Amino Acid Oxidoreductases; Animals; Male; Microchemistry; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Inbred Strains; Substrate Specificity; Tissue Distribution; Transaminases

1989
Enzymatic determination of L-phenylalanine and phenylpyruvate with L-phenylalanine dehydrogenase.
    Analytical biochemistry, 1988, May-01, Volume: 170, Issue:2

    Topics: Amino Acid Oxidoreductases; Amino Acids; Deamination; Phenylalanine; Phenylpyruvic Acids; Spectrophotometry; Substrate Specificity; Tyrosine

1988
Phenylalanine metabolites, attention span and hyperactivity.
    The American journal of clinical nutrition, 1985, Volume: 42, Issue:2

    Topics: Adolescent; Attention; Child; Child, Preschool; Female; Humans; Hyperkinesis; Infant; Infant, Newborn; Lactates; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids

1985
Effects of phenylalanine and its deaminated metabolites on Na+,K+-ATPase activity in synaptosomes from rat brain.
    Neurochemical research, 1982, Volume: 7, Issue:6

    Topics: Animals; Brain; Female; Kinetics; Lactates; Male; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship; Synaptosomes

1982
Mechanism of 3-phenylpyruvate-induced insulin release. Secretory, ionic and oxidative aspects.
    The Biochemical journal, 1983, Mar-15, Volume: 210, Issue:3

    Topics: Animals; Calcium; Dose-Response Relationship, Drug; Glucose; Glutamine; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Oxidation-Reduction; Phenylalanine; Phenylpyruvic Acids; Rats; Rubidium; Stimulation, Chemical

1983
Mechanism of 3-phenylpyruvate-induced insulin release from isolated pancreatic islets.
    The Biochemical journal, 1981, Aug-15, Volume: 198, Issue:2

    Topics: Amino Acids; Animals; Glutamate Dehydrogenase; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Mice; Oxidation-Reduction; Phenylalanine; Phenylpyruvic Acids; Stimulation, Chemical

1981
Alanine reverses the inhibitory effect of phenylalanine and its metabolites on Na+,K(+)-ATPase in synaptic plasma membranes from cerebral cortex of rats.
    Biochemical Society transactions, 1995, Volume: 23, Issue:2

    Topics: Alanine; Analysis of Variance; Animals; Cerebral Cortex; Kinetics; Lactates; Phenethylamines; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Synaptic Membranes

1995
Phenylpyruvic acid may be a direct precursor of mandelic acid without intermediate transamination of phenylalanine.
    Biochemical pharmacology, 1993, Dec-03, Volume: 46, Issue:11

    Topics: Animals; Female; Mandelic Acids; Phenethylamines; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Wistar

1993
Phenylalanine determined in plasma with use of phenylalanine dehydrogenase and a centrifugal analyzer.
    Clinical chemistry, 1993, Volume: 39, Issue:1

    Topics: Amino Acid Oxidoreductases; Autoanalysis; Humans; NAD; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Quality Control

1993
Alpha-keto acids are novel siderophores in the genera Proteus, Providencia, and Morganella and are produced by amino acid deaminases.
    Journal of bacteriology, 1993, Volume: 175, Issue:9

    Topics: Amino Acids; Biological Assay; Biological Transport; Caproates; Chromatography, High Pressure Liquid; Deamination; Enterobacteriaceae; Hydroxamic Acids; Iron; Keto Acids; Lactates; Leucine; Phenylalanine; Phenylpyruvic Acids; Proteus; Providencia; Siderophores; Structure-Activity Relationship; Tryptophan; Valine

1993
Phenylalanine utilization for protein synthesis in beta-phenylpyruvic acid treated Escherichia coli cells.
    Microbios, 1996, Volume: 87, Issue:351

    Topics: Amino Acids; Bacterial Proteins; Escherichia coli; Phenylalanine; Phenylpyruvic Acids; RNA, Transfer, Phe; Time Factors

1996
Phenylalanine- and tyrosine-auxotrophic mutants of Saccharomyces cerevisiae impaired in transamination.
    Molecular & general genetics : MGG, 1998, Volume: 257, Issue:2

    Topics: Amino Acids; Ammonia; Culture Media; Fungal Proteins; Genes, Fungal; Isoenzymes; Kynurenine; Lyases; Phenotype; Phenylalanine; Phenylpyruvic Acids; Saccharomyces cerevisiae; Substrate Specificity; Transaminases; Tyrosine; Urea

1998
Reversal of optical induction in transamination by regioisomeric bifunctionalized cyclodextrins.
    Bioorganic & medicinal chemistry, 1999, Volume: 7, Issue:5

    Topics: Amino Acids; Crystallography; Cyclodextrins; Isomerism; Kinetics; Models, Chemical; Models, Molecular; Phenylalanine; Phenylpyruvic Acids; Pyridoxamine; Transaminases

1999
Involvement of manganese in conversion of phenylalanine to benzaldehyde by lactic acid bacteria.
    Applied and environmental microbiology, 1999, Volume: 65, Issue:12

    Topics: Benzaldehydes; Cell-Free System; Kinetics; Lactobacillus; Manganese; Phenylalanine; Phenylpyruvic Acids; Species Specificity

1999
Prebiotic transamination.
    Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 1997, Volume: 27, Issue:4

    Topics: Alanine; Amino Acids; Evolution, Chemical; Glutamic Acid; Hydrogen-Ion Concentration; Keto Acids; Ketoglutaric Acids; Phenylalanine; Phenylpyruvic Acids; Pyruvic Acid; Transaminases

1997
Phenylalanine and phenylpyruvate inhibit ATP diphosphohydrolase from rat brain cortex.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2001, Volume: 19, Issue:7

    Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Cerebral Cortex; Hydrolysis; Kinetics; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Presynaptic Terminals; Rats; Rats, Wistar; Synaptosomes

2001
Aromatic amino acid biosynthesis and production of related compounds from p-hydroxyphenylpyruvic acid by rumen bacteria, protozoa and their mixture.
    Amino acids, 2002, Volume: 22, Issue:2

    Topics: Amino Acids, Aromatic; Animals; Bacteria; Chromatography, High Pressure Liquid; Eukaryota; Goats; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Rumen; Tyrosine

2002
Characterization of the inhibition of pyruvate kinase caused by phenylalanine and phenylpyruvate in rat brain cortex.
    Brain research, 2003, Apr-11, Volume: 968, Issue:2

    Topics: Adenosine Diphosphate; Alanine; Animals; Binding, Competitive; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Neural Inhibition; Phenylalanine; Phenylpyruvic Acids; Phosphoenolpyruvate; Pyruvate Kinase; Rats; Rats, Wistar

2003
Effects of phenylalanine and phenylpyruvate on ATP-ADP hydrolysis by rat blood serum.
    Amino acids, 2003, Volume: 24, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Apyrase; Hydrolysis; Kinetics; Male; Phenylalanine; Phenylpyruvic Acids; Rats; Rats, Wistar

2003
Identification and characterization of phenylpyruvate decarboxylase genes in Saccharomyces cerevisiae.
    Applied and environmental microbiology, 2003, Volume: 69, Issue:8

    Topics: Carboxy-Lyases; Phenylalanine; Phenylpyruvic Acids; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Substrate Specificity; Thiamine Pyrophosphate; Transcription, Genetic

2003
Utilization of phenylalanine, phenyllactic acid, and phenylpyruvic acid by Lactobacillus casei.
    The Journal of biological chemistry, 1956, Volume: 219, Issue:1

    Topics: Lactic Acid; Lacticaseibacillus casei; Lactobacillus; Phenylalanine; Phenylpyruvic Acids

1956
[Rapid method for research on the conversion of L-phenylalanine into phenylpyruvic acid].
    Annales de l'Institut Pasteur, 1956, Volume: 90, Issue:5

    Topics: Biochemical Phenomena; Phenylalanine; Phenylpyruvic Acids; Proteus

1956
Phenylketonuria VIII. Relation between age, serum phenylalanine level, and phenylpyruvic acid excretion.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1957, Volume: 94, Issue:1

    Topics: Biochemical Phenomena; Biological Transport; Body Fluids; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids

1957
The metabolism of p-methoxyphenylalanine and p-methoxyphenylpyruvate.
    The Journal of biological chemistry, 1957, Volume: 229, Issue:1

    Topics: Liver; Phenylalanine; Phenylpyruvic Acids

1957
Excretion of phenylalanine; report of two cases of phenyl pyruvic acid oligophrenia.
    Annales paediatriae Fenniae, 1957, Volume: 3, Issue:4

    Topics: Biological Transport; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pyruvic Acid

1957
Peptide and keto acid utilization in replacing phenylalanine in adaptive enzyme synthesis.
    The Journal of biological chemistry, 1958, Volume: 230, Issue:2

    Topics: Keto Acids; Lactobacillus; Lyases; Peptides; Phenylalanine; Phenylpyruvic Acids; Protein Biosynthesis

1958
Phenylpyruvic acid as a possible precursor of o-hydroxyphenylacetic acid in man.
    Science (New York, N.Y.), 1959, Jun-05, Volume: 129, Issue:3362

    Topics: Administration, Oral; Humans; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine

1959
[Determination of phenylalanine and phenylpyruvic acid in the blood and urine. Application to two cases of phenylpyruvic oligophrenia].
    Helvetica paediatrica acta, 1959, Volume: 14

    Topics: Body Fluids; Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids

1959
[Inversion of Damino acids in vitro. Effects of certain factors on the transreamination of phenylpyruvate by a homogenate of rat kidney].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1959, Volume: 153

    Topics: Animals; Biochemical Phenomena; Chromosome Inversion; In Vitro Techniques; Kidney; Phenylalanine; Phenylpyruvic Acids; Rats

1959
Effects of L-phenylalanine and sodium phenylpyruvate on the formation of melanin from L-tyrosine in melanoma.
    Nature, 1962, Jan-27, Volume: 193

    Topics: Melanins; Melanoma; Phenylalanine; Phenylpyruvic Acids; Sodium; Tyrosine

1962
Problems of routine screening for phenylketonuria.
    Lancet (London, England), 1962, Sep-08, Volume: 2, Issue:7254

    Topics: Humans; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids

1962
Influence of alpha-ketoacids on the respiration of brain in vitro.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 113

    Topics: Brain; In Vitro Techniques; Keto Acids; Leucine; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Valine

1963
Effect of phenulalanine and its metabolites on the brain serotonin level of the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1962, Volume: 111

    Topics: Animals; Brain; Phenylalanine; Phenylpyruvic Acids; Rats; Serotonin

1962
[PHENYLKETONURIA. APROPOS OF A FAMILIAL CASE].
    Pediatrie, 1963, Volume: 18

    Topics: Blood Chemical Analysis; Body Fluids; Diet; Diet Therapy; Electroencephalography; Genetics, Medical; Humans; Infant; Iproniazid; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pyridoxine; Tryptophan; Urine

1963
A STUDY OF THE INCIDENCE OF PHENYLKETONURIA IN INDIA.
    The Indian journal of medical research, 1963, Volume: 51

    Topics: Blood; Consanguinity; Epidemiology; Family; Humans; Incidence; India; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Pigmentation; Urine

1963
TYROSINOSIS.
    Annals of the New York Academy of Sciences, 1963, Dec-30, Volume: 111

    Topics: Alanine; Amino Acid Metabolism, Inborn Errors; Blood Chemical Analysis; Child; Genetics, Medical; Glycine; Metabolic Diseases; Phenols; Phenylalanine; Phenylpyruvic Acids; Tyrosine; Urine

1963
[RECENT KNOWLEDGE ABOUT THE PROBLEM OF PHENYLPYRUVIC OLIGOPHRENIA. FREQUENCY, GENETICS, BIOCHEMISTRY, DIAGNOSIS, AND THERAPEUTICS].
    La Semana medica, 1963, Oct-14, Volume: 123

    Topics: Asparagine; Biochemistry; Diet; Diet Therapy; Genetics, Medical; Glutamine; Humans; Knowledge; Nialamide; Pathology; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Prognosis; Urine

1963
URINARY PHENYLPYRUVIC ACID IN PHENYLKETONURIA.
    JAMA, 1964, May-25, Volume: 188

    Topics: Blood Chemical Analysis; Chlorides; Chromatography; Humans; Infant; Infant, Newborn; Iron; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Urine

1964
TRANSAMINATION OF AROMATIC AMINO ACIDS IN RAT BRAIN.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: 5-Hydroxytryptophan; Amino Acids, Aromatic; Brain; Chromatography; Dihydroxyphenylalanine; Keto Acids; Ketoglutaric Acids; Phenylalanine; Phenylpyruvic Acids; Rats; Research; Tissue Extracts; Transaminases; Tryptophan; Tyrosine

1964
SEROTONIN DEFICIENCY IN INFANCY AS ONE CAUSE OF A MENTAL DEFECT IN PHENYLKETONURIA.
    Science (New York, N.Y.), 1964, May-15, Volume: 144, Issue:3620

    Topics: Animals; Animals, Newborn; Behavior; Catecholamines; Chlorpromazine; Genetics; Learning; Metabolic Diseases; Metabolism; Mice; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Research; Reserpine; Serotonin; Toxicology; Tyrosine

1964
AMINO ACID METABOLISM IN KWASHIORKOR. II. METABOLISM OF PHENYLALANINE AND TYROSINE.
    Clinical science, 1964, Volume: 26

    Topics: Blood Chemical Analysis; Child; Chromatography; Dietary Proteins; Humans; Infant; Kwashiorkor; Milk; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Proteins; Tyrosine; Urine

1964
PREPARATION OF PREPHENIC ACID AND ITS CONVERSION TO PHENYLALANINE AND TYROSINE BY PLANT ENZYMES.
    Canadian journal of biochemistry, 1964, Volume: 42

    Topics: Autoanalysis; Barium; Cyclohexanecarboxylic Acids; Cyclohexenes; Escherichia coli; Fermentation; Glutamates; Infrared Rays; Ion Exchange Resins; NADP; Peptones; Phenylalanine; Phenylpyruvic Acids; Plants, Edible; Proteins; Research; Transaminases; Tyrosine; Yeasts

1964
STUDIES ON TYROSINOSIS: 1, EFFECT OF LOW-TYROSINE AND LOW-PHENYLALANINE DIET.
    British medical journal, 1964, Nov-07, Volume: 2, Issue:5418

    Topics: Acetates; Amino Acid Metabolism, Inborn Errors; Amino Acids; Child; Diet; Diet Therapy; Hepatomegaly; Humans; Kidney; Kidney Function Tests; Lactates; Liver Diseases; Liver Function Tests; Phenylalanine; Phenylpyruvic Acids; Phosphates; Renal Aminoacidurias; Rickets; Tyrosine; Urine

1964
SLOW EXPONENTIAL GROWTH OF ESCHERICHIA COLI IN PRESENCE OF RHO-FLUOROPHENYLALANINE. EFFECT OF THE ANALOG ON AROMATIC BIOSYNTHESIS.
    Biochimica et biophysica acta, 1964, Jun-22, Volume: 87

    Topics: Amino Acids; Carbon Isotopes; Cell Division; Drug Resistance; Drug Resistance, Microbial; Escherichia coli; Fluorocarbon Polymers; Mutation; Phenylalanine; Phenylpyruvic Acids; Research; Shikimic Acid; Tyrosine

1964
CHEMICAL DIAGNOSIS OF PHENYLKETONURIA. REPORT OF 8 CASES.
    Chinese medical journal (Peking, China : 1932), 1964, Volume: 83

    Topics: Adolescent; Blood Chemical Analysis; Body Fluids; Child; China; Chromatography; Clinical Laboratory Techniques; Genes; Humans; Infant; Infant, Newborn; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine; Urine

1964
CONVERSION OF L-PHENYLALANINE TO D-PHENYLALANINE BY CELL-FREE EXTRACTS OF BACILLUS BREVIS.
    Journal of biochemistry, 1964, Volume: 56

    Topics: Adenine Nucleotides; Adenosine Triphosphate; Amino Acid Oxidoreductases; Bacillus; Carbon Isotopes; Chromatography; D-Amino-Acid Oxidase; Isomerases; Metabolism; Phenylalanine; Phenylpyruvic Acids; Research

1964
EFFECTS OF ACID CATABOLITES ON ACTIVITY IN VITRO OF PHENYLALANINE HYDROXYLASE FROM RAT LIVER.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: Acetates; Benzoates; Cinnamates; Enzyme Inhibitors; Gentisates; In Vitro Techniques; Lactates; Liver; Mandelic Acids; Mixed Function Oxygenases; Pharmacology; Phenylacetates; Phenylalanine; Phenylalanine Hydroxylase; Phenylpyruvic Acids; Pyruvates; Rats; Research

1965
LEVOMEPROMAZINE (NOZINAN) MEDICATION AS A SOURCE OF ERROR IN THE LABORATORY DIAGNOSIS OF PHENYLKETONURIA.
    Scandinavian journal of clinical and laboratory investigation, 1965, Volume: 17

    Topics: Blood; Chlorides; Clinical Laboratory Techniques; Diagnosis; Humans; Indicators and Reagents; Methotrimeprazine; Pharmacology; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Urine

1965
ALPHA-KETO DERIVATIVES OF AMINO ACIDS AS INHIBITORS OF TRYPSINOGEN ACTIVATION.
    Archives of biochemistry and biophysics, 1965, Volume: 110

    Topics: Amino Acids; Arginine; Butyrates; Catalysis; Endopeptidases; Enzyme Inhibitors; Glutamates; Guanidines; Indoleacetic Acids; Indoles; Keto Acids; Ketoglutaric Acids; Leucine; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Research; Trypsinogen; Tryptophan; Tyrosine

1965
AMINO ACID ISOMERIZATION IN THE PRODUCTION OF L-PHENYLALANINE FROM D-PHENYLALANINE BY BACTERIA.
    Applied microbiology, 1965, Volume: 13

    Topics: Amino Acids; Ammonium Compounds; Centrifugation; Colorimetry; Culture Media; D-Amino-Acid Oxidase; Manometry; Methionine; Oxygen; Pharmacology; Phenylalanine; Phenylpyruvic Acids; Photometry; Pseudomonas; Quaternary Ammonium Compounds; Research; Threonine; Transaminases; Tryptophan; Urea; Valine

1965
ENZYMATIC FORMATION OF PHENYLPYRUVIC ACID IN PSEUDOMONAS SP. (ATCC 11299A) AND ITS REGULATION.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: Chemical Phenomena; Chemistry; Enzyme Inhibitors; Enzymes; Hydrogen-Ion Concentration; Phenylalanine; Phenylpyruvic Acids; Pseudomonas; Research; Tyrosine

1965
Response of lactic acid bacteria to amino acid derivatives. III. Effect of lyophilization on utilization of phenylalanine, phenyllactic acid, and phenylpyruvic acid.
    Archives of biochemistry and biophysics, 1952, Volume: 35, Issue:1

    Topics: Amino Acids; Arginine; Freeze Drying; Lactic Acid; Lactobacillus; Phenylalanine; Phenylpyruvic Acids

1952
A molecularly imprinted polymer-based synthetic transaminase.
    Journal of the American Chemical Society, 2004, Jul-14, Volume: 126, Issue:27

    Topics: Biomimetic Materials; Catalysis; Kinetics; Ligands; Methacrylates; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Phenylpyruvic Acids; Polymethacrylic Acids; Pyridoxal; Pyridoxamine; Transaminases

2004
Phenylacetate catabolism in Rhodococcus sp. strain RHA1: a central pathway for degradation of aromatic compounds.
    Journal of bacteriology, 2005, Volume: 187, Issue:13

    Topics: Acetaldehyde; Chromosomes, Bacterial; Electrophoresis, Gel, Two-Dimensional; Genes, Bacterial; GTP Cyclohydrolase; Multigene Family; Phenethylamines; Phenylacetates; Phenylalanine; Phenylbutyrates; Phenylethyl Alcohol; Phenylpyruvic Acids; Proteome; Rhodococcus

2005
Engineered phenylalanine dehydrogenase in organic solvents: homogeneous and biphasic enzymatic reactions.
    Organic & biomolecular chemistry, 2005, Dec-21, Volume: 3, Issue:24

    Topics: Amino Acid Oxidoreductases; Chemistry, Organic; Molecular Structure; Nitrogen Dioxide; Organic Chemistry Phenomena; Phenylalanine; Phenylpyruvic Acids; Protein Engineering; Solvents

2005
Chemical conversion of alpha-amino acids into alpha-keto acids by 4,5-epoxy-2-decenal.
    Journal of agricultural and food chemistry, 2006, Aug-09, Volume: 54, Issue:16

    Topics: Acetaldehyde; Aldehydes; Benzaldehydes; Epoxy Compounds; Hydrogen-Ion Concentration; Lipid Peroxidation; Maillard Reaction; Phenylalanine; Phenylpyruvic Acids; Time Factors

2006
Characterization and application of D-amino acid oxidase and catalase within permeabilized Pichia pastoris cells in bioconversions.
    Applied biochemistry and biotechnology, 2007, Volume: 136, Issue:3

    Topics: Biomass; Bioreactors; Biotechnology; Catalase; Cell Membrane Permeability; D-Amino-Acid Oxidase; Enzyme Stability; Fermentation; Hydrogen-Ion Concentration; Phenylalanine; Phenylpyruvic Acids; Pichia; Temperature; Time Factors

2007
Tissue-specific activation of mitogen-activated protein kinases for expression of transthyretin by phenylalanine and its metabolite, phenylpyruvic acid.
    Experimental & molecular medicine, 2010, Feb-28, Volume: 42, Issue:2

    Topics: Animals; Brain Stem; Disease Models, Animal; Gene Expression Regulation; Hep G2 Cells; Hepatocyte Nuclear Factor 4; Humans; Liver; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinase 3; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Prealbumin

2010
Identification of genes in the phenylalanine metabolic pathway by ectopic expression of a MYB transcription factor in tomato fruit.
    The Plant cell, 2011, Volume: 23, Issue:7

    Topics: Amino Acids, Dicarboxylic; Cyclohexanecarboxylic Acids; Cyclohexenes; Fruit; Gene Expression Regulation, Plant; Humans; Metabolic Networks and Pathways; Microarray Analysis; Molecular Sequence Data; Molecular Structure; Petunia; Phenylalanine; Phenylpyruvic Acids; Phylogeny; Plant Extracts; Plant Proteins; Plants, Genetically Modified; Proto-Oncogene Proteins c-myb; Recombinant Fusion Proteins; Solanum lycopersicum; Transaminases; Tyrosine; Volatile Organic Compounds

2011
Resolving phenylalanine metabolism sheds light on natural synthesis of penicillin G in Penicillium chrysogenum.
    Eukaryotic cell, 2012, Volume: 11, Issue:2

    Topics: Carboxy-Lyases; Decarboxylation; Metabolic Engineering; Penicillin G; Penicillium chrysogenum; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Saccharomyces cerevisiae; Transcriptome

2012
tyrB-2 and phhC genes of Pseudomonas putida encode aromatic amino acid aminotransferase isozymes: evidence at the protein level.
    Amino acids, 2013, Volume: 45, Issue:2

    Topics: Amino Acid Sequence; Base Sequence; Isoenzymes; Molecular Sequence Data; Phenylalanine; Phenylpyruvic Acids; Pseudomonas putida; Sequence Analysis, DNA; Transaminases

2013
An alternative pathway contributes to phenylalanine biosynthesis in plants via a cytosolic tyrosine:phenylpyruvate aminotransferase.
    Nature communications, 2013, Volume: 4

    Topics: Alternative Splicing; Cytosol; Petunia; Phenylalanine; Phenylpyruvic Acids; Plant Proteins; RNA Interference; Transaminases; Tyrosine

2013
Screening of phenylpyruvic acid producers and optimization of culture conditions in bench scale bioreactors.
    Bioprocess and biosystems engineering, 2014, Volume: 37, Issue:11

    Topics: Biomass; Bioreactors; Corynebacterium glutamicum; Culture Media; Fermentation; Industrial Microbiology; Morganella morganii; Phenylalanine; Phenylpyruvic Acids; Proteus vulgaris; Zygosaccharomyces

2014
In vivo instability of chorismate causes substrate loss during fermentative production of aromatics.
    Yeast (Chichester, England), 2014, Volume: 31, Issue:9

    Topics: Biosynthetic Pathways; Chorismic Acid; Cyclohexanecarboxylic Acids; Cyclohexenes; Fermentation; Gene Deletion; Metabolic Engineering; Phenylalanine; Phenylpyruvic Acids; Saccharomyces cerevisiae

2014
Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.
    Scientific reports, 2014, Nov-06, Volume: 4

    Topics: Adaptor Proteins, Signal Transducing; Biological Transport; Cell Differentiation; Cell Proliferation; Fusion Regulatory Protein-1; Gene Expression Regulation; Hemin; Humans; K562 Cells; Mechanistic Target of Rapamycin Complex 1; Models, Biological; Multiprotein Complexes; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Signal Transduction; TOR Serine-Threonine Kinases; Valine

2014
Production of phenylpyruvic acid from L-phenylalanine using an L-amino acid deaminase from Proteus mirabilis: comparison of enzymatic and whole-cell biotransformation approaches.
    Applied microbiology and biotechnology, 2015, Volume: 99, Issue:20

    Topics: Amino Acids; Ammonia-Lyases; Biotransformation; Cloning, Molecular; Escherichia coli; Gene Expression; Phenylalanine; Phenylpyruvic Acids; Proteus mirabilis; Recombinant Proteins

2015
Combination of phenylpyruvic acid (PPA) pathway engineering and molecular engineering of L-amino acid deaminase improves PPA production with an Escherichia coli whole-cell biocatalyst.
    Applied microbiology and biotechnology, 2016, Volume: 100, Issue:5

    Topics: Amidohydrolases; Biotransformation; Escherichia coli; Gene Knockout Techniques; Metabolic Engineering; Metabolic Networks and Pathways; Mutant Proteins; Phenylalanine; Phenylpyruvic Acids; Protein Engineering; Proteus mirabilis; Recombinant Proteins; Recombination, Genetic

2016
Construction and evaluation of a novel bifunctional phenylalanine-formate dehydrogenase fusion protein for bienzyme system with cofactor regeneration.
    Journal of industrial microbiology & biotechnology, 2016, Volume: 43, Issue:5

    Topics: Amino Acid Oxidoreductases; Bacillus; Candida; Coenzymes; Enzyme Stability; Formate Dehydrogenases; Formates; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Phenylpyruvic Acids; Recombinant Fusion Proteins; Stereoisomerism; Temperature

2016
Identification of a small protein domain present in all plant lineages that confers high prephenate dehydratase activity.
    The Plant journal : for cell and molecular biology, 2016, Volume: 87, Issue:2

    Topics: Amino Acids, Dicarboxylic; Cyclohexenes; Genes, Plant; Metabolic Networks and Pathways; Phenylalanine; Phenylpyruvic Acids; Phylogeny; Pinus; Plants; Prephenate Dehydratase; Tyrosine

2016
Two-Step Production of Phenylpyruvic Acid from L-Phenylalanine by Growing and Resting Cells of Engineered Escherichia coli: Process Optimization and Kinetics Modeling.
    PloS one, 2016, Volume: 11, Issue:11

    Topics: Bioreactors; Biotransformation; Escherichia coli; Genetic Engineering; Kinetics; Models, Biological; Oxygen; Phenylalanine; Phenylpyruvic Acids; Substrate Specificity; Time Factors

2016
In-silico and in-vitro investigation on the phenylalanine metabolites' interactions with hexokinase of Rat's brain mitochondria.
    Journal of bioenergetics and biomembranes, 2017, Volume: 49, Issue:2

    Topics: Animals; Brain; Glucose; Glycolysis; Hexokinase; Mitochondria; Molecular Docking Simulation; Phenylalanine; Phenylpyruvic Acids; Protein Binding; Rats

2017
Completion of the cytosolic post-chorismate phenylalanine biosynthetic pathway in plants.
    Nature communications, 2019, 01-03, Volume: 10, Issue:1

    Topics: Amino Acids, Dicarboxylic; Biosynthetic Pathways; Chorismate Mutase; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytosol; Phenylalanine; Phenylpyruvic Acids; Plants; Plastids; Prephenate Dehydratase; Transaminases; Transcription Initiation Site; Tyrosine

2019
Expression, characterization, and site-specific covalent immobilization of an L-amino acid oxidase from the fungus Hebeloma cylindrosporum.
    Applied microbiology and biotechnology, 2019, Volume: 103, Issue:5

    Topics: Enzymes, Immobilized; Escherichia coli; Hebeloma; L-Amino Acid Oxidase; Phenylalanine; Phenylpyruvic Acids; Recombinant Fusion Proteins

2019
Modulation of auxin formation by the cytosolic phenylalanine biosynthetic pathway.
    Nature chemical biology, 2020, Volume: 16, Issue:8

    Topics: Biosynthetic Pathways; Cytosol; Indoleacetic Acids; Indoles; Phenylalanine; Phenylpyruvic Acids; Plants; Tryptophan

2020
Process properties of an l-amino acid oxidase from Hebeloma cylindrosporum for the synthesis of phenylpyruvic acid from l-phenylalanine.
    Journal of biotechnology, 2020, Nov-10, Volume: 323

    Topics: Amino Acids; Biocatalysis; Biotransformation; Enzyme Stability; Hebeloma; L-Amino Acid Oxidase; Phenylalanine; Phenylpyruvic Acids; Substrate Specificity

2020
Human Serum Phenylpyruvate Quantification Using Responsive 2D Photonic Crystal Hydrogels via Chemoselective Oxime Ligation: Progress toward Developing Phenylalanine-Sensing Elements.
    ACS applied materials & interfaces, 2020, Sep-02, Volume: 12, Issue:35

    Topics: Amino Acid Oxidoreductases; Biosensing Techniques; Humans; Hydrogels; Limit of Detection; Oximes; Phenylalanine; Phenylpyruvic Acids; Photons

2020
Energy metabolism profile of the effects of amino acid treatment on hepatocytes: Phenylalanine and phenylpyruvate inhibit glycolysis of hepatocytes.
    Nutrition (Burbank, Los Angeles County, Calif.), 2021, Volume: 82

    Topics: Amino Acids; Energy Metabolism; Glycolysis; Hepatocytes; Phenylalanine; Phenylpyruvic Acids

2021
Biosynthesis of phenylpyruvic acid from l-phenylalanine using chromosomally engineered Escherichia coli.
    Biotechnology and applied biochemistry, 2022, Volume: 69, Issue:5

    Topics: Escherichia coli; Metabolic Engineering; Phenylalanine; Phenylpyruvic Acids; Plasmids

2022
Competitive, multi-objective, and compartmented Flux Balance Analysis for addressing tissue-specific inborn errors of metabolism.
    Journal of inherited metabolic disease, 2023, Volume: 46, Issue:4

    Topics: Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Phenylpyruvic Acids; Tyrosine

2023
Enzymatic synthesis of halogen derivatives of L-phenylalanine and phenylpyruvic acid stereoselectively labeled with hydrogen isotopes in the side chain.
    Journal of labelled compounds & radiopharmaceuticals, 2023, Volume: 66, Issue:11

    Topics: Deuterium; Halogens; Hydrogen; Phenylalanine; Phenylpyruvic Acids; Tritium

2023