phenylalanine and phenylalanine methyl ester

phenylalanine has been researched along with phenylalanine methyl ester in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19909 (18.00)18.7374
1990's20 (40.00)18.2507
2000's9 (18.00)29.6817
2010's12 (24.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akamatsu, M; Asao, M; Fujita, T; Iwamura, H1
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Cha, SH; Chairoungdua, A; Endou, H; Enomoto, A; Goya, T; Kanai, Y; Kim, DK; Kim, JY; Kobayashi, Y; Matsuo, H1
Rosenfeld, CS2
Lipsky, PE; Thiele, DL1
Leung, KH2
Andersen, DW; Burgert, SL; Schedl, HP; Stegink, LD; Takeuchi, H1
Chau, WK; Law, P1
Aldrich, WA; Rinehart, JJ; Triozzi, PL1
Evans, C; Rosenfeld, CS; Shadduck, RK1
Masucci, G; Mellstedt, H; Pihlstedt, P; Wersäll, P; Wigzell, H1
Cotgreave, I; Masucci, G; Mellstedt, H; Pihlstedt, P; Tribukait, B; Ullberg, M; Wersäll, P; Wigzell, H1
Hoyer, M; Lewis, W; Meineke, T; Rinehart, J; Zwilling, B1
Alsop, T; Dooley, DC; Haiber, LM; Law, P; Schwartz, GN; Smith, DM1
Boylan, J; Ellenbogen, R; Pueschel, SM1
Chua, BH; Lautensack, N; Long, WM; Morgan, HE1
Burton, EG; Dal Monte, P; Frank, P; Oppermann, JA; Spears, C1
Dimitrijević, B; Izbicka-Dimitrijević, E; Kochman, M1
Barlogie, B; Condino, J; Gazitt, Y; Hoffman, R; Jagannath, S; Lee, B; Reading, CC; Tricot, G; Vesole, DH; Wickrema, A1
Flores, A; Little, GH1
Connors, KA; Skwierczynski, RD1
Liebmann, C; Paegelow, I; Pineda De Castro, LF; Reissmann, S; Schwuchow, C; Seyfarth, L; Stewart, JM; Werner, H1
Muro, T; Nagao, T; Shimada, Y; Sugihara, A; Takenishi, S; Tominaga, Y; Watanabe, Y1
Bertoldi, M; Borri Voltattorni, C; Dominici, P; Moore, PS1
Castro, GD; Castro, JA1
Abe, T; Hirao, A; Kajiume, T; Kawano, Y; Kuroda, Y; Law, P; Makimoto, A; Nakagawa, R; Okamoto, Y; Sato, J; Takaue, Y; Watanabe, A; Watanabe, T1
Månsson, MO; Mosbach, K; Ramström, O; Ye, L1
Ansell, RJ; Månsson, MO; Mosbach, K; Ramström, O; Ye, L1
Klibanov, AM; Luque, S; Shin, JS1
Fu, H; Han, B; Zhao, YF1
KUK-MEIRI, S; LICHTENSTEIN, N1
Kowalczyk, W; Lammek, B; Trzepałka, E1
Concellon, C; Cowley, AR; Davies, SG; Garner, AC; Parkes, AL; Rodriguez-Solla, H; Smith, AD; Tamayo, JA1
Beck-Sickinger, AG; Neundorf, I; Rennert, R; Wespe, C1
Merz, K; Neundorf, I; Peindy N'Dongo, HW; Schatzschneider, U1
Asano, Y; Kira, I; Yokozeki, K1
Giralt, E; Malakoutikhah, M; Prades, R; Teixidó, M1
Aguiar, AS; Berthiau, AS; Caussanel, S; Chevarin, C; Farrington, DT; Hamon, M; Herrick-Davis, K; Lanfumey, L; Madjar, JJ; Martin, CB; Mongeau, R; Ramond, F1
du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C1
Bronich, TK; Desale, S; Kabanov, AV; Kim, JO; Oberoi, HS1
Budac, D; du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C; Smagin, G; Song, D1
Morilak, DA; Pehrson, AL; Sánchez, C; Wallace, A1
Başaran, E; Karaküçük-Iyidoğan, A; Oruç-Emre, EE; Schols, D1
Ji, S; Li, N; Qi, L; Wang, M1
Chen, G; Chen, SF; Feng, BM; Lu, XJ; Pei, YH; Wang, HF; Zhao, D1
Mastai, Y; Nadella, V; Paik, P; Prakash, H; Yamala, AK1
Bortoluzzi, VT; Brust, L; de Franceschi, ID; Preissler, T; Wannmacher, CMD1
Moukha-Chafiq, O; Reynolds, RC; Snowden, TS; Wilson, JC1

Trials

1 trial(s) available for phenylalanine and phenylalanine methyl ester

ArticleYear
Clinically applicable bulk isolation of blood CD34+ cells for autografting in children.
    Bone marrow transplantation, 1998, Volume: 22, Issue:10

    Topics: Adolescent; Antibodies, Monoclonal; Antigens, CD34; Blood Component Removal; Cells, Cultured; Child; Child, Preschool; Cryopreservation; Female; Flow Cytometry; Humans; Immunomagnetic Separation; Infant; Leukemia, Myeloid, Acute; Male; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Transplantation, Autologous

1998

Other Studies

49 other study(ies) available for phenylalanine and phenylalanine methyl ester

ArticleYear
Quantitative structure-activity relationships of the bitter thresholds of amino acids, peptides, and their derivatives.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:10

    Topics: Amino Acids; Humans; Mathematics; Peptides; Structure-Activity Relationship; Taste

1987
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location.
    Genomics, 2002, Volume: 79, Issue:1

    Topics: Amino Acid Sequence; Amino Acid Transport Systems, Neutral; Animals; Carrier Proteins; Chromosome Mapping; Chromosomes, Human, Pair 6; Humans; Molecular Sequence Data; Oocytes; Rats; Sequence Analysis, DNA; Sequence Homology; Xenopus laevis

2002
Potential of phenylalanine methylester as a bone marrow purging agent.
    Blood, 1992, Nov-01, Volume: 80, Issue:9

    Topics: Bone Marrow; Bone Marrow Purging; Colony-Forming Units Assay; Cyclophosphamide; Erythropoietin; Hematopoietic Cell Growth Factors; Humans; Kinetics; Leukemia, Myeloid; Leukemia, Promyelocytic, Acute; Phenylalanine; Recombinant Proteins; Stem Cell Factor; Time Factors; Tumor Cells, Cultured

1992
Spectrum of toxicities of amino acid methyl esters for myeloid cells is determined by distinct metabolic pathways.
    Blood, 1992, Feb-15, Volume: 79, Issue:4

    Topics: Adult; Ammonium Chloride; Cathepsin C; Cell Death; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Esterases; Glutamates; Granulocytes; Humans; Killer Cells, Natural; Leucine; Leukemia, Myeloid; Leukocytes, Mononuclear; Neutrophils; Phagocytes; Phenylalanine; T-Lymphocytes, Cytotoxic; Tumor Cells, Cultured

1992
Human lymphokine-activated killer (LAK) cells: III. Effect of L-phenylalanine methyl ester on LAK cell activation from human peripheral blood mononuclear cells: possible protease involvement of monocytes, natural killer cells and LAK cells.
    Cancer immunology, immunotherapy : CII, 1991, Volume: 34, Issue:1

    Topics: Chymotrypsin; Endopeptidases; Humans; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Lymphocyte Activation; Monocytes; Phenylalanine; Tosyllysine Chloromethyl Ketone; Tosylphenylalanyl Chloromethyl Ketone; Trypsin

1991
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:6

    Topics: Animals; Aspartame; Aspartic Acid; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver Circulation; Methanol; Perfusion; Phenylalanine; Swine; Tyrosine

1991
Effect of L-phenylalanine methyl ester on the colony formation of hematopoietic progenitor cells from human bone marrow.
    International journal of cell cloning, 1991, Volume: 9, Issue:3

    Topics: Bone Marrow; Bone Marrow Cells; Cells, Cultured; Hematopoiesis; Hematopoietic Stem Cells; Humans; Leukocytes, Mononuclear; Phenylalanine

1991
Human monocytes inhibit lymphokine-activated killer cell expansion in vitro.
    Molecular biotherapy, 1991, Volume: 3, Issue:1

    Topics: Cell Separation; Cytotoxicity, Immunologic; Humans; In Vitro Techniques; Interleukin-2; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Monocytes; Phenylalanine

1991
Human macrophage colony-stimulating factor induces macrophage colonies after L-phenylalanine methylester treatment of human marrow.
    Blood, 1990, Nov-01, Volume: 76, Issue:9

    Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Culture Media; Humans; Leukemia, Promyelocytic, Acute; Macrophage Colony-Stimulating Factor; Macrophages; Monocytes; Phenylalanine; Tumor Cells, Cultured

1990
Simplified long term large scale production of highly active human LAK cells for therapy.
    Medical oncology and tumor pharmacotherapy, 1990, Volume: 7, Issue:4

    Topics: Cells, Cultured; Cytotoxicity, Immunologic; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Leukapheresis; Leukocyte Count; Leukocytes, Mononuclear; Phenylalanine; Reference Values

1990
Generation of human LAK cells in tissue culture bags using recombinant IL-2 and serum free medium. Effects of pretreatment with phenylalanine-methylester.
    Acta oncologica (Stockholm, Sweden), 1990, Volume: 29, Issue:4

    Topics: Cell Count; Cell Survival; Culture Media; Culture Techniques; DNA; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Phenylalanine; Recombinant Proteins; Time Factors

1990
Characterization and modulation of human lymphokine (interleukin 2) activated killer cell induction.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Cytotoxicity, Immunologic; Humans; Interferons; Interleukin-1; Interleukin-2; Killer Cells, Natural; Kinetics; Leucine; Monocytes; Phenylalanine; Thymidine; Tritium

1986
Human lymphokine-activated killer (LAK) cells. I. Depletion of monocytes from peripheral blood mononuclear cells by L-phenylalanine methyl ester: an optimization of LAK cell generation at high cell density.
    Cancer immunology, immunotherapy : CII, 1989, Volume: 30, Issue:4

    Topics: Cell Separation; Cells, Cultured; Humans; Interleukin-2; Killer Cells, Lymphokine-Activated; Kinetics; Leukocyte Count; Lymphocyte Activation; Monocytes; Phenylalanine; Recombinant Proteins

1989
Removal of peripheral blood monocytes by phenylalanine methyl ester has no effect on the colony growth of hematopoietic progenitor cells.
    International journal of cell cloning, 1989, Volume: 7, Issue:2

    Topics: Cell Adhesion; Cell Separation; Colony-Forming Units Assay; Fetal Blood; Hematopoietic Stem Cells; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Phenylalanine

1989
Studies on experimentally induced hyperphenylalaninemia.
    Journal of mental deficiency research, 1988, Volume: 32 ( Pt 4)

    Topics: Animals; Disease Models, Animal; Drug Combinations; Female; Fenclonine; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Rats, Inbred Strains; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination

1988
Effects of amino acid methyl esters on cardiac lysosomes and protein degradation.
    The American journal of physiology, 1983, Volume: 245, Issue:1

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Glucose; Heart; Insulin; Leucine; Lysosomes; Male; Methionine; Myocardium; Phenylalanine; Proteins; Rats; Rats, Inbred Strains

1983
Absorption by the rhesus monkey of phenylalanine methyl ester and species differences in its metabolism by blood, plasma and intestinal mucosa.
    The Journal of nutrition, 1984, Volume: 114, Issue:10

    Topics: Animals; Dogs; Female; Humans; Hydrolysis; Intestinal Absorption; Intestinal Mucosa; Macaca mulatta; Phenylalanine; Rats; Species Specificity

1984
A kinetic analysis of the distinct regulatory sites on rabbit muscle pyruvate kinase.
    Biochimica et biophysica acta, 1982, Apr-21, Volume: 703, Issue:1

    Topics: Alanine; Animals; Binding Sites; Macromolecular Substances; Mathematics; Muscles; Phenylalanine; Pyruvate Kinase; Rabbits

1982
Purified CD34+ Lin- Thy+ stem cells do not contain clonal myeloma cells.
    Blood, 1995, Jul-01, Volume: 86, Issue:1

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, CD34; Antigens, Differentiation; Antigens, Differentiation, T-Lymphocyte; Blood Component Removal; CD56 Antigen; Cell Separation; Centrifugation; Consensus Sequence; Countercurrent Distribution; Cyclophosphamide; DNA Primers; Feasibility Studies; Flow Cytometry; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cell Transplantation; Hematopoietic Stem Cells; Humans; Immunoglobulin Heavy Chains; Immunophenotyping; Membrane Glycoproteins; Multiple Myeloma; N-Glycosyl Hydrolases; Neoplastic Stem Cells; Phenylalanine; Plasma Cells; Polymerase Chain Reaction; Thy-1 Antigens

1995
Inhibition of programmed cell death by catalase and phenylalanine methyl ester.
    Comparative biochemistry and physiology. Comparative physiology, 1993, Volume: 105, Issue:1

    Topics: Animals; Apoptosis; Catalase; Culture Techniques; Hydrogen Peroxide; Macrophages; Phenylalanine; Prolactin; Rana catesbeiana; Superoxide Dismutase; Superoxides

1993
Antileukemic activity of phenylalanine methyl ester (PME): a lysosomotropic peptide methyl ester.
    Stem cells (Dayton, Ohio), 1994, Volume: 12, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blast Crisis; Child; Cyclophosphamide; Drug Screening Assays, Antitumor; Drug Synergism; Female; Humans; Leukemia; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Middle Aged; Monocytes; Phenylalanine; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Temperature; Tumor Cells, Cultured

1994
Demethylation kinetics of aspartame and L-phenylalanine methyl ester in aqueous solution.
    Pharmaceutical research, 1993, Volume: 10, Issue:8

    Topics: Aspartame; Chromatography, High Pressure Liquid; Dealkylation; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Phenylalanine; Potentiometry; Solutions; Water

1993
Highly selective bradykinin agonists and antagonists with replacement of proline residues by N-methyl-D- and L-phenylalanine.
    Journal of medicinal chemistry, 1996, Feb-16, Volume: 39, Issue:4

    Topics: Amino Acid Sequence; Animals; Bradykinin; Cell Membrane; Female; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Male; Molecular Sequence Data; Muscle, Smooth; Phenylalanine; Proline; Protein Conformation; Rats; Receptors, Bradykinin; Stereoisomerism; Structure-Activity Relationship; Uterus

1996
A unique enzyme from Saccharothrix sp. catalyzing D-amino acid transfer.
    Biochimica et biophysica acta, 1997, Jan-04, Volume: 1337, Issue:1

    Topics: Actinomycetales; Acyltransferases; Aminoacyltransferases; Bacterial Proteins; Enzyme Inhibitors; Isomerism; Phenylalanine; Substrate Specificity

1997
Aromatic amino acid methyl ester analogs form quinonoidal species with Dopa decarboxylase.
    FEBS letters, 1997, Jul-21, Volume: 412, Issue:1

    Topics: Amino Acids; Dopa Decarboxylase; Esters; Hydrogen-Ion Concentration; Methylation; Phenylalanine; Pyridoxal Phosphate; Spectrophotometry; Tyrosine

1997
Promotion of the formation of phenylalanine-thymine cross-linked products by free radicals formed during carbon tetrachloride activation with benzoyl peroxide in model systems. A mass spectrometric structural study.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 98, Issue:1

    Topics: Benzoyl Peroxide; Carbon Tetrachloride; Cross-Linking Reagents; Free Radicals; Gas Chromatography-Mass Spectrometry; Phenylalanine; Thymine

1997
A new application of molecularly imprinted materials.
    Journal of molecular recognition : JMR, 1998,Winter, Volume: 11, Issue:1-6

    Topics: Adsorption; Aspartame; Aspartic Acid; In Vitro Techniques; Molecular Mimicry; Phenylalanine; Polymers; Thermolysin

1998
Use of molecularly imprinted polymers in a biotransformation process.
    Biotechnology and bioengineering, 1999, Sep-20, Volume: 64, Issue:6

    Topics: Aspartame; Aspartic Acid; Biotransformation; Methacrylates; Phenylalanine; Polymers; Thermolysin

1999
Improving lipase enantioselectivity in organic solvents by forming substrate salts with chiral agents.
    Biotechnology and bioengineering, 2000, Sep-05, Volume: 69, Issue:5

    Topics: Biotechnology; Burkholderia cepacia; Lipase; Models, Molecular; Phenylalanine; Salts; Solvents; Stereoisomerism; Substrate Specificity

2000
Reaction of ADP with amino acid methyl esters mediated by trimethylsilyl chloride.
    Chemical communications (Cambridge, England), 2003, Jan-07, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Trimethylsilyl Compounds

2003
Effect of methanol and dioxan on the action of chymotrypsin on L-phenylalanine methyl ester.
    Experientia, 1960, Mar-15, Volume: 16

    Topics: Chymotrypsin; Dioxanes; Ethanol; Heterocyclic Compounds; Methanol; Phenylalanine

1960
Cis/trans conformational equilibrium across the N-methylphenylalanine- N-methylphenylalanine peptide bond of arginine vasopressin analogs.
    The journal of peptide research : official journal of the American Peptide Society, 2004, Volume: 63, Issue:4

    Topics: Arginine Vasopressin; Hydrogen Bonding; Isomerism; Magnetic Resonance Spectroscopy; Molecular Conformation; Peptides, Cyclic; Phenylalanine

2004
Asymmetric conjugate reductions with samarium diiodide: asymmetric synthesis of (2S,3R)- and (2S,3S)-[2-2H,3-2H]-leucine-(S)-phenylalanine dipeptides and (2S,3R)-[2-(2)H,3-2H]-phenylalanine methyl ester.
    Organic & biomolecular chemistry, 2005, Apr-21, Volume: 3, Issue:8

    Topics: Crystallography, X-Ray; Dipeptides; Iodides; Magnetic Resonance Spectroscopy; Molecular Structure; Oxidation-Reduction; Phenylalanine; Samarium; Stereoisomerism

2005
Developing novel hCT derived cell-penetrating peptides with improved metabolic stability.
    Biochimica et biophysica acta, 2006, Volume: 1758, Issue:3

    Topics: Amino Acid Sequence; Calcitonin; Cell-Penetrating Peptides; Cells, Cultured; Circular Dichroism; Drug Carriers; Half-Life; Humans; Molecular Sequence Data; Peptide Fragments; Phenylalanine

2006
Synthesis, characterization, X-ray crystallography, and cytotoxicity of a cymantrene keto carboxylic acid for IR labelling of bioactive peptides on a solid support.
    Journal of inorganic biochemistry, 2008, Volume: 102, Issue:12

    Topics: Carboxylic Acids; Cell Line, Tumor; Enkephalins; Humans; Organometallic Compounds; Peptides; Phenylalanine; Spectrophotometry, Infrared

2008
Screening, purification, and identification of the enzyme producing N-(L-alpha-L-aspartyl)-L-phenylalanine methyl ester from l-isoasparagine and L-phenylalanine methyl ester.
    Journal of bioscience and bioengineering, 2009, Volume: 108, Issue:3

    Topics: Asparagine; Biotechnology; Catalysis; Citrobacter; Dipeptidases; Electrophoresis, Polyacrylamide Gel; Enterobacteriaceae; Escherichia coli; Hydrogen-Ion Concentration; Models, Chemical; Phenylalanine; Recombinant Proteins; Salmonella typhimurium; Shigella flexneri

2009
N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Aminolevulinic Acid; Animals; Animals, Newborn; Astrocytes; Biological Transport; Blood Vessels; Blood-Brain Barrier; Brain; Cattle; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Coculture Techniques; Drug Carriers; Endothelial Cells; gamma-Aminobutyric Acid; Mass Spectrometry; Molecular Structure; Nipecotic Acids; Oligopeptides; Phenylalanine; Rats

2010
RNA splicing and editing modulation of 5-HT(2C) receptor function: relevance to anxiety and aggression in VGV mice.
    Molecular psychiatry, 2013, Volume: 18, Issue:6

    Topics: Aggression; Animals; Anxiety; Bioluminescence Resonance Energy Transfer Techniques; Brain; Defense Mechanisms; Disease Models, Animal; Gene Expression Regulation; Glycine; HEK293 Cells; Humans; Hydroxyindoleacetic Acid; Interpersonal Relations; Mice; Mice, Inbred C57BL; Mutation; Phenylalanine; Protein Binding; Protein Isoforms; Receptor, Serotonin, 5-HT2C; RNA Editing; RNA Precursors; RNA Splicing; RNA, Messenger; Transfection; Ultrasonics; Valine

2013
Vortioxetine dose-dependently reverses 5-HT depletion-induced deficits in spatial working and object recognition memory: a potential role for 5-HT1A receptor agonism and 5-HT3 receptor antagonism.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Indazoles; Maze Learning; Memory Disorders; Memory, Short-Term; Phenylalanine; Piperazines; Protein Binding; Pyridines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT1A; Receptors, Serotonin, 5-HT3; Recognition, Psychology; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT3 Receptor Antagonists; Sulfides; Time Factors; Tritium; Tropanes; Vortioxetine

2014
Polypeptide nanogels with hydrophobic moieties in the cross-linked ionic cores: synthesis, characterization and implications for anticancer drug delivery.
    Journal of drug targeting, 2013, Volume: 21, Issue:10

    Topics: Animals; Antibiotics, Antineoplastic; Breast Neoplasms; Cross-Linking Reagents; Doxorubicin; Drug Carriers; Drug Delivery Systems; Female; Gels; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Mice; Nanoparticles; Ovarian Neoplasms; Particle Size; Phenylalanine; Polyethylene Glycols; Polyglutamic Acid; Polymers; Time Factors; Xenograft Model Antitumor Assays

2013
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine

2014
Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats.
    The international journal of neuropsychopharmacology, 2014, Volume: 17, Issue:10

    Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Attention; Autoradiography; Body Weight; Cold Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Learning Disabilities; Male; Phenylalanine; Piperazines; Rats; Rats, Sprague-Dawley; Reversal Learning; Serotonin; Stress, Psychological; Sulfides; Vortioxetine

2014
Synthesis of Novel Chiral Sulfonamide-Bearing 1,2,4-Triazole-3-thione Analogs Derived from D- and L-Phenylalanine Esters as Potential Anti-Influenza Agents.
    Chirality, 2016, Volume: 28, Issue:6

    Topics: Animals; Antiviral Agents; Chemistry Techniques, Synthetic; Dogs; Drug Evaluation, Preclinical; HeLa Cells; Humans; Influenza A Virus, H1N1 Subtype; Madin Darby Canine Kidney Cells; Magnetic Resonance Spectroscopy; Molecular Structure; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Triazoles

2016
Preparation of amino acid-based polymer functionalized magnetic nanoparticles as adsorbents for analysis of plant growth regulators in bean sprouts.
    Talanta, 2016, Sep-01, Volume: 158

    Topics: 2,4-Dichlorophenoxyacetic Acid; Adsorption; Fabaceae; Magnetic Phenomena; Magnetite Nanoparticles; Phenylalanine; Plant Growth Regulators; Polymethacrylic Acids; Seedlings; Solid Phase Extraction; Spectroscopy, Fourier Transform Infrared

2016
Three new amino acid derivatives from edible mushroom Pleurotus ostreatus.
    Journal of Asian natural products research, 2017, Volume: 19, Issue:12

    Topics: Agaricales; Antioxidants; Candida albicans; Flavins; Leucine; Microbial Sensitivity Tests; Molecular Structure; Phenylalanine; Pleurotus

2017
Poly-N-acryloyl-(l-phenylalanine methyl ester) hollow core nanocapsules facilitate sustained delivery of immunomodulatory drugs and exhibit adjuvant properties.
    Nanoscale, 2017, Sep-28, Volume: 9, Issue:37

    Topics: Adjuvants, Immunologic; Animals; Drug Delivery Systems; HeLa Cells; Humans; Immunomodulation; Macrophages; Mice; Nanocapsules; Nitric Oxide; Phenylalanine; RAW 264.7 Cells

2017
Creatine plus pyruvate supplementation prevents oxidative stress and phosphotransfer network disturbances in the brain of rats subjected to chemically-induced phenylketonuria.
    Metabolic brain disease, 2019, Volume: 34, Issue:6

    Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain; Creatine; Disease Models, Animal; Energy Metabolism; Oxidative Stress; Phenylalanine; Phenylketonurias; Pyruvic Acid; Rats; Rats, Wistar; Reactive Oxygen Species

2019
Parallel Solution Phase Synthesis and Preliminary Biological Activity of a 5'-Substituted Cytidine Analog Library.
    ACS combinatorial science, 2019, 09-09, Volume: 21, Issue:9

    Topics: Amines; Carboxylic Acids; Cytidine; Hydrolysis; Molecular Structure; Phenylalanine; Small Molecule Libraries; Structure-Activity Relationship

2019