phenylalanine and paclitaxel

phenylalanine has been researched along with paclitaxel in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (16.00)18.2507
2000's7 (28.00)29.6817
2010's12 (48.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
DiCosmo, F; Fett-Neto, AG; Melanson, SJ; Sakata, K1
Gerok, W; Häussinger, D; Stoll, B; vom Dahl, S1
Hess, WM; Kramer, R; Sears, J; Sidhu, RS; Strobel, G; Yang, X1
Gu, B; Li, M; Lü, H; Wu, D1
Chen, Y; Hu, Q; Wu, Y; Zhu, W1
Cho, YW; Huh, KM; Lee, J; Lee, SC; Park, K1
Dansette, PM; Jaouen, M; Johnson, EF; Macherey, AC; Mansuy, D; Marques-Soares, C; Melet, A; Sari, MA; Schoch, GA1
Balachandran, R; Curran, DP; Day, BW; Edler, MC; Fournier, JH; Hamel, E; Madiraju, C; Raccor, BS; Shin, Y; Zhu, G1
Bemani, E; Ghanati, F; Jamshidi, M; Rezaei, A1
Bronich, TK; Cohen, SM; Desale, SS; Kabanov, AV; Zhao, Y1
Gioannini, TL; Jerala, R; Oblak, A; Resman, N; Weiss, JP1
Altabella, T; Cusido, RM; Goossens, A; Moyano, E; Notredame, C; Onrubia, M; Osuna, L; Palazon, J; Ramírez-Estrada, K; Vanden Bossche, R1
Braet, F; Gloria, D; Su, Y; Thordarson, P; Truong, WT1
Hayes, DF; Henry, NL; Hertz, DL; Kim, JH; Smith, EML; Stringer, KA; Sun, Y; Vangipuram, K; Yeomans, L1
Meng, Y; Wu, J1
Han, S; Meng, Y; Wu, J; Yin, J1
Foster, C; Klettke, KL; Mutatu, W; Walker, KD1
de Wildeman, S; Feringa, BL; Janssen, DB; Poelarends, GJ; Szymanski, W; Wietzes, P; Wu, B1
Furmanowa, M; Kokoszka, A; Pietrosiuk, A; Syklowska-Baranek, K1
Feng, L; Geiger, J; Strom, S; Walker, KD; Wanninayake, U1
Deporre, Y; Ondari, M; Walker, KD; Wanninayake, U1
Bartsch, S; de Wildeman, S; Dijkstra, BW; Feringa, BL; Heberling, MM; Janssen, DB; Poelarends, GJ; Szymański, W; Wu, B; Wybenga, GG1
Hou, Q; Liu, Y; Wang, K1
Dijkstra, BW; Feringa, BL; Janssen, DB; Szymanski, W; Wu, B; Wybenga, GG1
Du, G; Ge, F; Li, W; Liu, Y; Song, P; Tang, H; Tao, Y; Zhu, L1

Other Studies

25 other study(ies) available for phenylalanine and paclitaxel

ArticleYear
Improved growth and taxol yield in developing calli of Taxus cuspidata by medium composition modification.
    Bio/technology (Nature Publishing Company), 1993, Volume: 11, Issue:6

    Topics: 2,4-Dichlorophenoxyacetic Acid; Adenine; Caseins; Cell Division; Cells, Cultured; Culture Media; Gibberellins; Hydrogen-Ion Concentration; Kinetin; Paclitaxel; Phenylalanine; Plant Cells; Plants; Protein Hydrolysates; Sucrose

1993
Inhibition of proteolysis by cell swelling in the liver requires intact microtubular structures.
    The Biochemical journal, 1995, Jun-01, Volume: 308 ( Pt 2)

    Topics: Animals; Bile; Cell Size; Cells, Cultured; Colchicine; Cycloheximide; Cytochalasin B; Demecolcine; Endopeptidases; In Vitro Techniques; Liver; Male; Microtubules; Paclitaxel; Phenylalanine; Rats; Rats, Wistar; Taurocholic Acid; Water-Electrolyte Balance

1995
Taxol from Pestalotiopsis microspora, an endophytic fungus of Taxus wallachiana.
    Microbiology (Reading, England), 1996, Volume: 142 ( Pt 2)

    Topics: Acetic Acid; Antineoplastic Agents, Phytogenic; Biotechnology; Drug Screening Assays, Antitumor; Ecosystem; Fermentation; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Microscopy, Electron, Scanning; Mitosporic Fungi; Paclitaxel; Phenylalanine; Spores, Fungal; Trees; Tumor Cells, Cultured

1996
Potentiation of docetaxel antitumor activity by batimastat against mouse forestomach carcinoma.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2000, Volume: 19, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Dose-Response Relationship, Drug; Male; Mice; Paclitaxel; Phenylalanine; Stomach Neoplasms; Taxoids; Thiophenes

2000
[Effects of phenylalanine, sucrose and mannitol on the growth and production of taxol, baccatin III and 10-deacetylbaccatin III in suspension cells of Taxus media].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1998, Volume: 33, Issue:2

    Topics: Alkaloids; Cell Division; Cells, Cultured; Mannitol; Paclitaxel; Phenylalanine; Sucrose; Taxoids; Taxus; Triterpenes

1998
Hydrotropic agents for study of in vitro paclitaxel release from polymeric micelles.
    Journal of controlled release : official journal of the Controlled Release Society, 2004, Jun-18, Volume: 97, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Chromatography, High Pressure Liquid; Drug Carriers; Excipients; Micelles; Paclitaxel; Particle Size; Phenylalanine; Polyethylene Glycols; Proteins; Sodium Salicylate; Solubility; Time Factors; Water

2004
Analysis of human cytochrome P450 2C8 substrate specificity using a substrate pharmacophore and site-directed mutants.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Amiodarone; Animals; Arginine; Aryl Hydrocarbon Hydroxylases; Asparagine; Catalysis; Chromans; Computer Simulation; Cytochrome P-450 CYP2C8; Diclofenac; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; Isoleucine; Models, Molecular; Mutagenesis, Site-Directed; Paclitaxel; Phenylalanine; Rabbits; Serine; Substrate Specificity; Sulfonamides; Thiazolidinediones; Tretinoin; Troglitazone

2004
Synthesis and biological evaluation of (-)-16-normethyldictyostatin: a potent analogue of (-)-dictyostatin.
    Organic letters, 2005, Jul-07, Volume: 7, Issue:14

    Topics: Animals; Antineoplastic Agents; Brain; Cattle; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Macrolides; Molecular Structure; Paclitaxel; Phenylalanine; Stereoisomerism; Structure-Activity Relationship; Tubulin; Valine

2005
Effect of phenylalanine on Taxol production and antioxidant activity of extracts of suspension-cultured hazel (Corylus avellana L.) cells.
    Journal of natural medicines, 2013, Volume: 67, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Cell Survival; Corylus; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Paclitaxel; Phenols; Phenylalanine; Plant Extracts; Time Factors

2013
Biodegradable hybrid polymer micelles for combination drug therapy in ovarian cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Nov-10, Volume: 171, Issue:3

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cisplatin; Delayed-Action Preparations; Female; Glutamic Acid; Humans; Mice; Mice, Nude; Micelles; Ovarian Neoplasms; Ovary; Paclitaxel; Phenylalanine; Polyethylene Glycols

2013
Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Feb-15, Volume: 192, Issue:4

    Topics: Acylation; Animals; Binding Sites; Cell Line; Enzyme Activation; Glycolipids; HEK293 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Lipid A; Lymphocyte Antigen 96; Mice; Paclitaxel; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Toll-Like Receptor 4; Tubulin Modulators

2014
Transcript profiling of jasmonate-elicited Taxus cells reveals a β-phenylalanine-CoA ligase.
    Plant biotechnology journal, 2016, Volume: 14, Issue:1

    Topics: Amino Acid Sequence; Amplified Fragment Length Polymorphism Analysis; Bridged-Ring Compounds; Chromatography, High Pressure Liquid; Computer Simulation; Cyclopentanes; Cytosol; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Plant; Genes, Plant; Genetic Association Studies; Ligases; Models, Molecular; Oxylipins; Paclitaxel; Phenylalanine; Plant Proteins; RNA, Messenger; Sequence Alignment; Tandem Mass Spectrometry; Taxoids; Taxus

2016
Dissolution and degradation of Fmoc-diphenylalanine self-assembled gels results in necrosis at high concentrations in vitro.
    Biomaterials science, 2015, Volume: 3, Issue:2

    Topics: Animals; Cell Survival; Colorectal Neoplasms; Dipeptides; Fluorenes; Fluorouracil; Humans; Hydrogels; Molecular Structure; Paclitaxel; Peptides; Phenylalanine; Solubility

2015
Pharmacometabolomics reveals a role for histidine, phenylalanine, and threonine in the development of paclitaxel-induced peripheral neuropathy.
    Breast cancer research and treatment, 2018, Volume: 171, Issue:3

    Topics: Adult; Aged; Biomarkers; Breast Neoplasms; Female; Histidine; Humans; Magnetic Resonance Spectroscopy; Metabolomics; Middle Aged; Paclitaxel; Peripheral Nervous System Diseases; Phenylalanine; Threonine

2018
One-Step and Facile Synthesis of Poly(phenylalanine) as a Robust Drug Carrier for Enhanced Cancer Therapy.
    ACS applied materials & interfaces, 2021, Oct-27, Volume: 13, Issue:42

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Movement; Cell Proliferation; Cell Survival; Cells, Cultured; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Female; Humans; Materials Testing; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Paclitaxel; Phenylalanine; Polymers; Rats; Rats, Sprague-Dawley

2021
Therapeutic Copolymer from Salicylic Acid and l-Phenylalanine as a Nanosized Drug Carrier for Orthotopic Breast Cancer with Lung Metastasis.
    ACS applied materials & interfaces, 2023, Sep-06, Volume: 15, Issue:35

    Topics: Drug Carriers; Humans; Lung Neoplasms; Paclitaxel; Phenylalanine; Polymers

2023
Unusual mechanism for an aminomutase rearrangement: retention of configuration at the migration termini.
    Biochemistry, 2007, Aug-28, Volume: 46, Issue:34

    Topics: Amino Acid Sequence; Catalysis; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Phenylalanine; Phenylalanine Ammonia-Lyase; Sequence Homology, Amino Acid; Stereoisomerism; Substrate Specificity; Taxus

2007
Enzymatic synthesis of enantiopure alpha- and beta-amino acids by phenylalanine aminomutase-catalysed amination of cinnamic acid derivatives.
    Chembiochem : a European journal of chemical biology, 2009, Jan-26, Volume: 10, Issue:2

    Topics: Amination; Ammonia; Biocatalysis; Cinnamates; Escherichia coli; Gene Expression; Imidazoles; Intramolecular Transferases; Phenylalanine; Stereoisomerism; Substrate Specificity; Taxus

2009
Enhancement of taxane production in hairy root culture of Taxus x media var. Hicksii.
    Journal of plant physiology, 2009, Nov-15, Volume: 166, Issue:17

    Topics: Acetates; Alkaloids; Antineoplastic Agents, Phytogenic; Benzoates; Biomass; Culture Media; Cyclopentanes; Oxylipins; Phenylalanine; Plant Growth Regulators; Plant Roots; Plants, Genetically Modified; Taxoids; Taxus; Tissue Culture Techniques

2009
Mechanistic, mutational, and structural evaluation of a Taxus phenylalanine aminomutase.
    Biochemistry, 2011, Apr-12, Volume: 50, Issue:14

    Topics: Amino Acid Sequence; Biocatalysis; Catalytic Domain; Cinnamates; Crystallography, X-Ray; Kinetics; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Mutation; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Proteins; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Substrate Specificity; Taxus

2011
(S)-Styryl-α-alanine used to probe the intermolecular mechanism of an intramolecular MIO-aminomutase.
    Biochemistry, 2011, Nov-22, Volume: 50, Issue:46

    Topics: Alanine; Catalytic Domain; Cinnamates; Kinetics; Phenylalanine; Phenylalanine Ammonia-Lyase; Stereoisomerism; Substrate Specificity; Taxus

2011
Mechanism-inspired engineering of phenylalanine aminomutase for enhanced β-regioselective asymmetric amination of cinnamates.
    Angewandte Chemie (International ed. in English), 2012, Jan-09, Volume: 51, Issue:2

    Topics: Amination; Cinnamates; Models, Molecular; Mutation; Phenylalanine; Phenylalanine Ammonia-Lyase; Protein Engineering; Stereoisomerism; Substrate Specificity; Taxus

2012
Insight into the mechanism of aminomutase reaction: a case study of phenylalanine aminomutase by computational approach.
    Journal of molecular graphics & modelling, 2013, Volume: 46

    Topics: Ammonia; Catalytic Domain; Computer Simulation; Intramolecular Transferases; Isomerism; Models, Molecular; Phenylalanine; Plant Proteins; Quantum Theory; Taxus

2013
Structural investigations into the stereochemistry and activity of a phenylalanine-2,3-aminomutase from Taxus chinensis.
    Biochemistry, 2014, May-20, Volume: 53, Issue:19

    Topics: Amino Acid Motifs; Amino Acid Substitution; Intramolecular Transferases; Mutation, Missense; Phenylalanine; Plant Proteins; Taxus

2014
One step synthesis of unnatural β-arylalanines using mutant phenylalanine aminomutase from Taxus chinensis with high β-regioselectivity.
    Enzyme and microbial technology, 2018, Volume: 114

    Topics: Biocatalysis; Catalytic Domain; Cinnamates; Mutation; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Proteins; Stereoisomerism; Substrate Specificity; Taxus

2018