phenylalanine and organophosphonates

phenylalanine has been researched along with organophosphonates in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199012 (24.00)18.7374
1990's13 (26.00)18.2507
2000's20 (40.00)29.6817
2010's5 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Becker, EL; Kegeles, SW; Showell, HJ; Tsung, P1
Filipiak, A; Janas, KM; Knypl, JS; Kowalik, J; Mastalerz, P1
Haenni, AL; Lucas-Lenard, J; Tao, P1
Danenberg, PV; Santi, DV; Satterly, P1
Taylor, AN; Wasserman, RH1
Drews, J; Grasmuk, H; Nolan, RD1
Arai, KI; Inoue-Yokosawa, N; Kawakita, M; Kaziro, Y; Yokosawa, H1
Chase, R; Gillam, IC; Tener, GM1
Inoue-Yokosawa, N; Ishikawa, C; Kaziro, Y1
Kaji, A; Otaka, T1
Cohen, LB; Goldberg, IH; Herner, AE1
Anderson, JW; Fewden, L1
Ishida, M; Maruyama, M; Saitoh, T; Shinozaki, H1
Hangauer, DG; Kim, MH; Lai, JH1
De Lombaert, S; Ghai, RD; Jeng, AY; Trapani, AJ; Webb, RL1
Berry, C; Blanchard, L; De Lombaert, S; el-Chehabi, L; Erion, MD; Ghai, RD; Sakane, Y; Tan, J; Trapani, AJ1
Carretero, OA; Liu, YH; Peterson, E; Yang, XP1
Chappell, MC; Ferrario, CM; Iyer, SN1
Cipriano, A; Maniara, WM; Powell, ML1
Corvol, P; Iturrioz, X; Llorens-Cortès, C; Vazeux, G1
Battistini, B; Jeng, AY; Pelletier, S; Sirois, P1
Burke, TR; Cao, T; Kelley, J; King, CR; Milne, GW; Voigt, JH; Yao, ZJ1
Akagi, H; Hosie, AM; Ishida, M; Shinozaki, H1
Barker, S; Mitchell, JA; Rees, GM; Walcot, NR; Warner, TD; Wood, EG; Woods, M1
Azimioara, MD; Bohacek, RS; Botfield, MC; Dalgarno, DC; Holt, DA; Madden, L; Narula, SS; Shakespeare, WC; Yuan, RW1
Battistini, B; Escher, E; Jeng, AY; Pham, D; Sirois, P1
Boileau, G; Dai, J; Geng, Y; Giancotti, FG; Knudsen, B; Nanus, DM; Navarro, D; Papandreou, CN; Shen, R; Sumitomo, M; Walburg, M1
Battistini, B; Jeng, AY; Wright, JL1
De Campo, BA; Goldie, RG; Henry, PJ; Jeng, AY1
Amrhein, N; Appert, C; Zoń, J1
Julkunen-Titto, R; Ruuhola, T1
Asakuma, J; Asano, T; Hayakawa, M; Nanus, DM; Sumitomo, M1
Barbier, S; Henry, JP; Jeng, AY; Monteil, C; Mulder, P; Renet, S; Thuillez, C1
Emoto, N1
Bindu, LK; Burke, TR; Fisher, RJ; Kang, SU; Karki, RG; Nicklaus, MC; Oishi, S; Wang, X; Worthy, KM1
Beselman, A; Boresch, S; Leitgeb, M; MacKerell, AD1
Battistini, B; Blouin, A; Daull, P; Jeng, AY; Nantel, F; Sirois, P1
Adiarto, S; Emoto, N; Isaka, D; Jeng, AY; Masuda, S; Raharjo, SB; Yokoyama, M1
Kiss, Z; Le Du, MH; Llinas, P; Ménez, A; Millán, JL; Stigbrand, T; Stura, EA1
Arsenault, D; Battistini, B; Beaudoin, M; Belleville, K; Benrezzak, O; Blouin, A; Cayer, J; Daull, P; Jeng, AY; Nantel, F; Pheng, LH; Sirois, P1
Chen, HK; Su, CK1
Borysko, KZ; Breitenbach, JM; Drach, JC; Eriksson, U; Hilfinger, JM; Kashemirov, BA; Kijek, P; Kim, JS; McKenna, CE; Mitchell, S1
Feng, YQ; Li, T; Lin, B; Yu, QW1
Cole, PA; Szewczuk, LM; Tarrant, MK1
Cox, RA; Deyo, DJ; Hawkins, HK; Herndon, DN; Jacob, S; Traber, DL1
Cairo, CW; Downey, AM; Tulsi, NS1
Martin, SL; Moffitt, KL; Walker, B1
Akhtar, TA; Pichersky, E1
Ballet, S; Guillemyn, K; Jida, M; Tourwé, D; Urbanczyk-Lipkowska, Z; Van der Poorten, O1
Bertani, F; Dalcanale, E; Pedrini, A1

Reviews

1 review(s) available for phenylalanine and organophosphonates

ArticleYear
[Physiological and pathophysiological roles of the endothelin converting enzymes].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 9

    Topics: Animals; Aspartic Acid Endopeptidases; Benzazepines; Benzofurans; Drug Design; Endothelin-Converting Enzymes; Glycopeptides; Heart Failure; Humans; Hypertension; Metalloendopeptidases; Mice; Mice, Knockout; Myocardial Infarction; Organophosphonates; Phenylalanine; Tetracyclines; Tetrazoles

2004

Other Studies

49 other study(ies) available for phenylalanine and organophosphonates

ArticleYear
Isolation of an N-acetyl-DL-phenylalanine beta-naphthyl esterase from rabbit peritoneal polymorphonuclear leukocytes.
    Biochimica et biophysica acta, 1975, Sep-22, Volume: 403, Issue:1

    Topics: Aminopeptidases; Animals; Cations, Divalent; Chemotaxis; Hydrogen-Ion Concentration; Kinetics; Neutrophils; Organophosphonates; Phenylalanine; Rabbits

1975
1-Amino-2-phenylethylphosphonic acid: an inhibitor of L-phenylalanine ammonia-lyase in vitro.
    Acta biochimica Polonica, 1985, Volume: 32, Issue:2

    Topics: Ammonia-Lyases; Kinetics; Organophosphonates; Organophosphorus Compounds; Phenylalanine; Phenylalanine Ammonia-Lyase; Plants; Stereoisomerism; Structure-Activity Relationship

1985
Further studies on bacterial polypeptide elongation.
    Cold Spring Harbor symposia on quantitative biology, 1969, Volume: 34

    Topics: Amino Acids; Bacterial Proteins; Binding Sites; Carbon Isotopes; Centrifugation, Density Gradient; Escherichia coli; Guanine Nucleotides; Organophosphonates; Peptide Biosynthesis; Phenylalanine; Phosphoric Monoester Hydrolases; Puromycin; Ribosomes; RNA, Bacterial; RNA, Transfer; Transferases; Tritium

1969
Phenylalanyl transfer ribonucleic acid synthetase from Escherichia coli. Reaction parameters and order of substrate addition.
    Biochemistry, 1971, Dec-07, Volume: 10, Issue:25

    Topics: Acylation; Adenosine; Adenosine Triphosphate; Amino Acyl-tRNA Synthetases; Amino Alcohols; Carbon Isotopes; Catalysis; Diphosphates; Escherichia coli; Ethanol; Fluorine; Kinetics; Magnesium; Models, Chemical; Nucleosides; Organophosphonates; Oxidation-Reduction; Periodic Acid; Phenylalanine; Phosphorus Isotopes; Protein Binding; RNA, Transfer; Sodium Chloride; Structure-Activity Relationship

1971
Intestinal absorption of phosphate in the chick: effect of vitamin D and other parameters.
    The Journal of nutrition, 1973, Volume: 103, Issue:4

    Topics: Acetates; Animals; Arsenic; Chelating Agents; Chickens; Cholecalciferol; Dose-Response Relationship, Drug; Duodenum; Ethanol; Glycols; Ileum; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Intestine, Small; Jejunum; Organophosphonates; Osmolar Concentration; Phenylalanine; Phosphates; Phosphorus Isotopes; Vitamin D Deficiency

1973
Elongation factor 1 from ascites tumor cells: interaction with ribosomes and elongation factor 2.
    European journal of biochemistry, 1974, Oct-02, Volume: 48, Issue:2

    Topics: Animals; Binding Sites; Carcinoma, Ehrlich Tumor; Cell-Free System; Cells, Cultured; Guanine Nucleotides; Guanosine Triphosphate; Organophosphonates; Peptide Elongation Factors; Phenylalanine; Poly U; Protein Biosynthesis; Ribosomes; RNA, Transfer

1974
The role of guanosine triphosphate hydrolysis in elongation factor Tu-promoted binding of aminoacyl transfer ribonucleic acid to ribosomes.
    The Journal of biological chemistry, 1973, Jan-10, Volume: 248, Issue:1

    Topics: Acetates; Binding Sites; Carbon Isotopes; Centrifugation, Density Gradient; Dipeptides; Escherichia coli; Guanine Nucleotides; Guanosine Triphosphate; Hydrolysis; Organophosphonates; Peptide Elongation Factors; Phenylalanine; Protein Binding; Ribosomes; RNA, Transfer

1973
Changes in levels of amino acid acceptors in tRNA from Escherichia coli grown under various conditions.
    Archives of biochemistry and biophysics, 1974, Volume: 163, Issue:1

    Topics: Amino Acyl-tRNA Synthetases; Aminobutyrates; Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Densitometry; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorine; Mutation; Organophosphonates; Phenylalanine; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Temperature; Threonine; Time Factors; Transfer RNA Aminoacylation; Tyrosine; Valine

1974
The role of guanosine triphosphate in translocation reaction catalyzed by elongation factor G.
    The Journal of biological chemistry, 1974, Jul-10, Volume: 249, Issue:13

    Topics: Acetamides; Binding Sites; Carbon Radioisotopes; Escherichia coli; Guanine Nucleotides; Guanosine Triphosphate; Organophosphonates; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Elongation Factors; Phenylalanine; Poly U; Puromycin; Ribosomes; RNA, Transfer

1974
Inhibitory effect of EF G and GMPPCP on peptidyl transferase.
    FEBS letters, 1974, Aug-30, Volume: 44, Issue:3

    Topics: Acyltransferases; Binding Sites; Carbon Radioisotopes; Centrifugation, Density Gradient; Chromatography, Gel; Escherichia coli; Guanine Nucleotides; Isotope Labeling; Macromolecular Substances; Methionine; Organophosphonates; Peptide Chain Elongation, Translational; Peptide Chain Initiation, Translational; Peptide Elongation Factors; Phenylalanine; Protein Binding; Protein Biosynthesis; Puromycin; Ribosomes; RNA, Bacterial; RNA, Transfer; Spectrophotometry, Ultraviolet; Tritium

1974
Stabilization of N-acetylphenylalanyl transfer ribonucleic acid binding to ribosomes by sparsomycin.
    Biochemistry, 1969, Volume: 8, Issue:4

    Topics: Anti-Bacterial Agents; Carbon Isotopes; Centrifugation, Density Gradient; Chloramphenicol; Erythromycin; Escherichia coli; Guanine Nucleotides; Magnesium; Nucleosides; Organophosphonates; Peptides; Phenylalanine; Puromycin; Quaternary Ammonium Compounds; Ribosomes; RNA, Bacterial; RNA, Transfer; Stimulation, Chemical

1969
1-amino-2-phenylethane 1-phosphonic acid: a specific competitive inhibitor of phenylalanyl-tRNA synthetase.
    Chemico-biological interactions, 1970, Volume: 2, Issue:1

    Topics: Amino Acyl-tRNA Synthetases; Kinetics; Leucine; Organophosphonates; Phenylalanine; Plants; Threonine; Tyrosine; Valine

1970
A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord.
    British journal of pharmacology, 1994, Volume: 113, Issue:1

    Topics: Animals; Animals, Newborn; Electrophysiology; GABA Antagonists; Glycine; Neurotransmitter Agents; Organophosphonates; Phenylalanine; Rats; Rats, Wistar; Receptors, Glycine; Spinal Cord; Structure-Activity Relationship; Strychnine; Synaptosomes

1994
Tetrapeptide tyrosine kinase inhibitors. Enantioselective synthesis of p-hydroxymethyl-L-phenylalanine, incorporation into a tetrapeptide, and subsequent elaboration into p-(R,S-hydroxyphosphonomethyl)-L-phenylalanine.
    International journal of peptide and protein research, 1994, Volume: 44, Issue:5

    Topics: Amino Acid Sequence; Molecular Sequence Data; Oligopeptides; Organophosphonates; Phenylalanine; Protein-Tyrosine Kinases; Stereoisomerism

1994
Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.
    Biochemical and biophysical research communications, 1994, Oct-14, Volume: 204, Issue:1

    Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; Cell Membrane; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Kidney Cortex; Kinetics; Male; Metalloendopeptidases; Molecular Sequence Data; Neprilysin; Oligopeptides; Organophosphonates; Phenylalanine; Protein Precursors; Rats; Rats, Inbred SHR; Substrate Specificity; Tetrazoles

1994
N-Phosphonomethyl dipeptides and their phosphonate prodrugs, a new generation of neutral endopeptidase (NEP, EC 3.4.24.11) inhibitors.
    Journal of medicinal chemistry, 1994, Feb-18, Volume: 37, Issue:4

    Topics: Animals; Antihypertensive Agents; Biological Availability; Biphenyl Compounds; Blood Pressure; Half-Life; Neprilysin; Organophosphonates; Phenylalanine; Phosphopeptides; Prodrugs; Rats; Structure-Activity Relationship

1994
Effect of neutral endopeptidase 24.11 inhibition on myocardial ischemia/reperfusion injury: the role of kinins.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:2

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Kinins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Neprilysin; Organophosphonates; Phenylalanine; Polysaccharides; Protease Inhibitors; Rats; Rats, Inbred Lew

1997
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2

    Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Heart Rate; Hypertension; Kinetics; Lisinopril; Losartan; Male; Neprilysin; Organophosphonates; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin-Angiotensin System

1998
Quantitative analytical methods for the determination of a new hypertension drug, CGS 25462, and its metabolites (CGS 25659 and CGS 24592) in human plasma by high-performance liquid chromatography.
    Journal of chromatography. B, Biomedical sciences and applications, 1998, Mar-20, Volume: 706, Issue:2

    Topics: Administration, Oral; Antihypertensive Agents; Biphenyl Compounds; Chromatography, High Pressure Liquid; Circadian Rhythm; Half-Life; Humans; Male; Organophosphonates; Phenylalanine; Prodrugs; Protease Inhibitors; Reproducibility of Results; Sensitivity and Specificity; Temperature; Time Factors

1998
A tyrosine residue essential for catalytic activity in aminopeptidase A.
    The Biochemical journal, 1997, Nov-01, Volume: 327 ( Pt 3)

    Topics: Amino Acid Substitution; Aminopeptidases; Animals; Binding Sites; COS Cells; Enzyme Inhibitors; Glutamates; Glutamyl Aminopeptidase; Histidine; Imidazoles; Kinetics; Metalloendopeptidases; Mutagenesis, Site-Directed; Organophosphonates; Phenylalanine; Recombinant Proteins; Tyrosine

1997
Effects of dual endothelin-converting enzyme/neutral endopeptidase inhibitors, CGS 26303 and CGS 26393, on lipopolysaccharide or interleukin-1 beta-stimulated release of endothelin from guinea pig tracheal epithelial cells.
    Journal of cardiovascular pharmacology, 1998, Volume: 31 Suppl 1

    Topics: Animals; Aspartic Acid Endopeptidases; Cells, Cultured; Endothelin-1; Endothelin-Converting Enzymes; Epithelial Cells; Guinea Pigs; Interleukin-1; Lipopolysaccharides; Male; Metalloendopeptidases; Organophosphonates; Phenylalanine; Protease Inhibitors; Tetrazoles; Trachea

1998
Potent inhibition of Grb2 SH2 domain binding by non-phosphate-containing ligands.
    Journal of medicinal chemistry, 1999, Jan-14, Volume: 42, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Asparagine; Female; GRB2 Adaptor Protein; Humans; Ligands; Models, Molecular; Molecular Mimicry; Organophosphonates; Phenylalanine; Phosphotyrosine; Protein Binding; Proteins; Receptor, ErbB-2; Recombinant Proteins; src Homology Domains; Structure-Activity Relationship; Surface Plasmon Resonance; Tumor Cells, Cultured

1999
Actions of 3-[2-phosphonomethyl[1,1-biphenyl]-3-yl]alanine (PMBA) on cloned glycine receptors.
    British journal of pharmacology, 1999, Volume: 126, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Glycine; Glycine Agents; Oocytes; Organophosphonates; Phenylalanine; Picrotoxin; Receptors, Glycine; Recombinant Proteins; Sesterterpenes; Strychnine; Xenopus laevis

1999
Endothelin-1 is induced by cytokines in human vascular smooth muscle cells: evidence for intracellular endothelin-converting enzyme.
    Molecular pharmacology, 1999, Volume: 55, Issue:5

    Topics: Aspartic Acid Endopeptidases; Cells, Cultured; Cytokines; Drug Interactions; Endothelin-1; Endothelin-Converting Enzymes; Glycopeptides; Humans; Interferon-gamma; Mammary Arteries; Metalloendopeptidases; Muscle, Smooth, Vascular; Organophosphonates; Phenylalanine; Protease Inhibitors; RNA, Messenger; Saphenous Vein; Tetrazoles; Tumor Necrosis Factor-alpha

1999
An efficient synthesis of a 4'-phosphonodifluoromethyl-3'-formyl-phenylalanine containing SRC SH2 ligand.
    Bioorganic & medicinal chemistry letters, 1999, Nov-01, Volume: 9, Issue:21

    Topics: Binding Sites; Cysteine; Fluorine Compounds; Ligands; Molecular Structure; Organophosphonates; Phenylalanine; Protein Binding; Protein-Tyrosine Kinases; src Homology Domains

1999
Effects of a selective neutral endopeptidase and a nonselective neutral endopeptidase/endothelin-converting enzyme inhibitor on lipopolysaccharide-induced endotoxaemia in anaesthetized Sprague-Dawley rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1

    Topics: Acid-Base Equilibrium; Animals; Aspartic Acid Endopeptidases; Blood Cell Count; Endothelin-Converting Enzymes; Endotoxemia; Hemodynamics; Lipopolysaccharides; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Tetrazoles

2000
Neutral endopeptidase inhibits prostate cancer cell migration by blocking focal adhesion kinase signaling.
    The Journal of clinical investigation, 2000, Volume: 106, Issue:11

    Topics: Animals; Bombesin; Cell Movement; COS Cells; Culture Media, Serum-Free; DNA, Recombinant; Endothelin-1; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Male; Membrane Proteins; Neprilysin; Organophosphonates; Phenylalanine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; src-Family Kinases; Tumor Cells, Cultured

2000
Effect of ECE and NEP inhibition on cigarette smoke-induced cell proliferation in the rat lung.
    Inhalation toxicology, 2001, Volume: 13, Issue:6

    Topics: Administration, Inhalation; Animals; Bromodeoxyuridine; Bronchi; Cell Division; Drug Interactions; Endothelium, Vascular; Glycopeptides; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Pulmonary Alveoli; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Smoking; Tetrazoles

2001
Role of endothelin-converting enzyme, chymase and neutral endopeptidase in the processing of big ET-1, ET-1(1-21) and ET-1(1-31) in the trachea of allergic mice.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Animals; Aspartic Acid Endopeptidases; Benzofurans; Chymases; Egg Hypersensitivity; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; In Vitro Techniques; Male; Mast Cells; Metalloendopeptidases; Mice; Mice, Inbred CBA; Muscle Contraction; Neprilysin; Organophosphonates; Ovalbumin; Peptide Fragments; Phenylalanine; Protein Precursors; Random Allocation; Serine Endopeptidases; Trachea

2002
Kinetic analysis of the inhibition of phenylalanine ammonia-lyase by 2-aminoindan-2-phosphonic acid and other phenylalanine analogues.
    Phytochemistry, 2003, Volume: 62, Issue:3

    Topics: Binding Sites; Binding, Competitive; Enzyme Inhibitors; Indans; Isoenzymes; Kinetics; Organophosphonates; Petroselinum; Phenylalanine; Phenylalanine Ammonia-Lyase

2003
Trade-off between synthesis of salicylates and growth of micropropagated Salix pentandra.
    Journal of chemical ecology, 2003, Volume: 29, Issue:7

    Topics: Adaptation, Physiological; Animals; Feeding Behavior; Indans; Insecta; Organophosphonates; Phenylalanine; Plants, Edible; Salicylates; Salix

2003
Chemosensitization of androgen-independent prostate cancer with neutral endopeptidase.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-01, Volume: 10, Issue:1 Pt 1

    Topics: Androgens; Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Cells, Cultured; Drug Resistance, Neoplasm; Epithelial Cells; Etoposide; Humans; Male; Mitochondria; Neoplasms, Hormone-Dependent; Neprilysin; Organophosphonates; Phenylalanine; Prostate; Prostatic Neoplasms; Protein Kinase C; Protein Kinase C-delta; Recombinant Proteins

2004
Sustained improvement of cardiac function and prevention of cardiac remodeling after long-term dual ECE-NEP inhibition in rats with congestive heart failure.
    Journal of cardiovascular pharmacology, 2004, Volume: 43, Issue:4

    Topics: Animals; Aspartic Acid Endopeptidases; Blood Pressure; Cardiac Output; Endothelin-Converting Enzymes; Heart Failure; Heart Rate; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Rats; Rats, Wistar; Tetrazoles; Ventricular Remodeling

2004
Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Binding Sites; Cyclization; GRB2 Adaptor Protein; Models, Molecular; Molecular Conformation; Molecular Mimicry; Organophosphonates; Phenylalanine; Phosphopeptides; Phosphotyrosine; Protein Binding; src Homology Domains; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

2005
Unexpected relative aqueous solubilities of a phosphotyrosine analogue and two phosphonate derivatives.
    Journal of the American Chemical Society, 2005, Apr-06, Volume: 127, Issue:13

    Topics: Computer Simulation; Models, Molecular; Organophosphonates; Peptides; Phenylalanine; Phosphotyrosine; Solubility; src Homology Domains; Thermodynamics; Water

2005
Triple vasopeptidase inhibition of angiotensin-converting enzyme/neutral endopeptidase/endothelin-converting enzyme activities on the hemodynamic profile of chronically instrumented unrestrained conscious spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aspartic Acid Endopeptidases; Benzazepines; Benzofurans; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Endothelin-Converting Enzymes; Heart Rate; Hypertension; Infusions, Intra-Arterial; Male; Metalloendopeptidases; Neprilysin; Organophosphonates; Phenylalanine; Rats; Rats, Inbred SHR; Time Factors

2004
Dual ECE/NEP inhibition on cardiac and neurohumoral function during the transition from hypertrophy to heart failure in rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Cardiac Output, Low; Cardiomegaly; Collagen; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Fibrosis; Heart; Male; Metalloendopeptidases; Myocardium; Neprilysin; Neurotransmitter Agents; Organophosphonates; Phenylalanine; Rats; Rats, Inbred Dahl; RNA, Messenger; Tetrazoles; Thiazepines

2005
Structural studies of human placental alkaline phosphatase in complex with functional ligands.
    Journal of molecular biology, 2005, Jul-15, Volume: 350, Issue:3

    Topics: Adenosine Monophosphate; Alkaline Phosphatase; Binding Sites; Catalytic Domain; Cell Proliferation; Crystallography, X-Ray; Down-Regulation; Fibroblasts; Humans; Hydrolysis; Ligands; Models, Molecular; Molecular Conformation; Nitrophenols; Organophosphonates; Phenylalanine; Placenta; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary

2005
Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats.
    American journal of hypertension, 2005, Volume: 18, Issue:12 Pt 1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Benzazepines; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Hypertension; Indoles; Male; Metalloendopeptidases; Neprilysin; Nitric Oxide; Organophosphonates; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species

2005
Endogenous activation of nicotinic receptors underlies sympathetic tone generation in neonatal rat spinal cord in vitro.
    Neuropharmacology, 2006, Volume: 51, Issue:7-8

    Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Animals; Animals, Newborn; Autonomic Fibers, Preganglionic; Cholinergic Fibers; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; Excitatory Amino Acid Antagonists; GABA-A Receptor Antagonists; Glycine; In Vitro Techniques; Interneurons; Kynurenic Acid; Mecamylamine; Nerve Tissue Proteins; Nicotinic Agonists; Nicotinic Antagonists; Organophosphonates; Phenylalanine; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Spinal Cord; Splanchnic Nerves; Sympathetic Fibers, Postganglionic; Synaptic Transmission

2006
Synthesis and biological activation of an ethylene glycol-linked amino acid conjugate of cyclic cidofovir.
    Bioorganic & medicinal chemistry letters, 2007, Feb-01, Volume: 17, Issue:3

    Topics: Amino Acids; Animals; Antiviral Agents; Biological Availability; Biotransformation; Cell Survival; Cidofovir; Cytosine; Ethylene Glycol; Half-Life; Humans; Hydrolysis; KB Cells; Magnetic Resonance Spectroscopy; Organophosphonates; Peptide Transporter 1; Phenylalanine; Prodrugs; Rats; Symporters; Valine; Viral Plaque Assay

2007
Synthesis and chromatographic properties of a chiral stationary phase derived from bovine serum albumin immobilized on magnesia-zirconia using phosphonate spacers.
    Journal of separation science, 2007, Volume: 30, Issue:6

    Topics: Animals; Cattle; Chromatography, Liquid; Dansyl Compounds; Dinitrobenzenes; Fosfomycin; Leucine; Magnesium Oxide; Molecular Structure; Organic Chemicals; Organophosphonates; Pharmaceutical Preparations; Phenylalanine; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Temperature; Tryptophan; Valine; Zirconium

2007
Protein phosphorylation by semisynthesis: from paper to practice.
    Methods in enzymology, 2009, Volume: 462

    Topics: Alanine; Animals; Humans; Inteins; Organophosphonates; Phenylalanine; Phosphoamino Acids; Phosphopeptides; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Recombinant Fusion Proteins

2009
Mechanisms of toxic smoke inhalation and burn injury: role of neutral endopeptidase and vascular leakage in mice.
    Toxicology mechanisms and methods, 2009, Volume: 19, Issue:3

    Topics: Animals; Burns; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Neprilysin; Organophosphonates; Phenylalanine; Protease Inhibitors; Pulmonary Edema; Smoke Inhalation Injury

2009
A protected l-bromophosphonomethylphenylalanine amino acid derivative (BrPmp) for synthesis of irreversible protein tyrosine phosphatase inhibitors.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Amino Acid Sequence; Amino Acids; Binding, Competitive; Enzyme Inhibitors; Fluorenes; Organophosphonates; Phenylalanine; Protein Tyrosine Phosphatases

2010
Chymotrypsin-like serine proteinases are involved in the maintenance of cell viability.
    Biochimie, 2012, Volume: 94, Issue:12

    Topics: Apoptosis; Biological Transport; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Survival; Chymotrypsin; Dose-Response Relationship, Drug; HeLa Cells; Humans; Microscopy, Confocal; Organophosphonates; Phenylalanine; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Rhodamines; Serine Proteases; Serine Proteinase Inhibitors

2012
Veratrole biosynthesis in white campion.
    Plant physiology, 2013, Volume: 162, Issue:1

    Topics: Amino Acid Sequence; Animals; Anisoles; Benzoic Acid; Biosynthetic Pathways; Carbon Isotopes; DNA, Complementary; Flowers; Guaiacol; Indans; Methylation; Oils, Volatile; Organophosphonates; Phenylalanine; Phenylalanine Ammonia-Lyase; Plant Oils; Plant Proteins; Pollination; Salicylic Acid; Sequence Analysis, Protein; Silene

2013
T3P-Promoted, Mild, One-Pot Syntheses of Constrained Polycyclic Lactam Dipeptide Analogues via Stereoselective Pictet-Spengler and Meyers Lactamization Reactions.
    Organic letters, 2015, Sep-18, Volume: 17, Issue:18

    Topics: Anhydrides; Dipeptides; Lactams; Models, Molecular; Molecular Conformation; Molecular Structure; Organophosphonates; Phenylalanine; Stereoisomerism

2015
Fluorinated Tetraphosphonate Cavitands.
    Molecules (Basel, Switzerland), 2018, Oct-17, Volume: 23, Issue:10

    Topics: Calixarenes; Cations; Ethers, Cyclic; Fluorine; Halogenation; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphonates; Phenylalanine; Resorcinols; Sarcosine

2018