phenylalanine and naltrexone

phenylalanine has been researched along with naltrexone in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's8 (44.44)18.2507
2000's5 (27.78)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bhargava, HN1
Legator, MS; Truong, L; Ward, JB1
Fournié-Zaluski, MC; Noble, F; Roques, BP; Turcaud, S1
Blommaert, A; Fournié-Zaluski, MC; Noble, F; Roques, BP1
Corringer, PJ; Dauge, V; Roques, BP1
Noble, F; Roques, BP; Smadja, C1
Krylatov, AV; Lishmanov, IuB; Maslov, LN; Uskina, EV1
Fournié-Zaluski, MC; Fuentes, JA; Hernando, F; Roques, BP; Ruiz-Gayo, M1
Gilbert-Rahola, J; Maldonado, R; Micó, JA; Roques, BP; Smadja, C; Tejedor-Real, P1
Besson, JM; Catheline, G; Fournié-Zaluski, MC; Honoré, P; Le Guen, S; Roques, BP1
Boucher, M; Coudoré-Civiale, MA; Eschalier, A; Fournié-Zaluski, MC; Méen, M; Roques, BP1
Blum, K; Braverman, ER; Chen, TJ; Hopper, D; Payte, JT; Schoolfield, J; Stanford, M1
Guen, SL; Kieffer, BL; Nieto, MM; Noble, F; Roques, BP1
Folk, JE; Jutkiewicz, EM; Mosberg, HI; Rice, KC; Sobczyk-Kojiro, K; Torregrossa, MM; Watson, SJ; Woods, JH1
Benturquia, N; Bilkei-Gorzo, A; Noble, F; Roques, BP; Zimmer, A1
Bouvier, M; Kobayashi, H; Lackman, JJ; Leskelä, TT; Petäjä-Repo, UE; Vierimaa, MM1
Akbarali, HI; Dewey, WL; Komla, E; Obeng, S; Selley, DE; Stevens, DL; Wang, H; Zhang, Y; Zheng, Y1
Corsetti, M; Pannemans, J1

Reviews

1 review(s) available for phenylalanine and naltrexone

ArticleYear
Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders?
    Current opinion in pharmacology, 2018, Volume: 43

    Topics: Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Defecation; Diarrhea; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Imidazoles; Inflammatory Bowel Diseases; Laxatives; Morphinans; Naltrexone; Narcotic Antagonists; Phenylalanine; Polyethylene Glycols; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Signal Transduction

2018

Trials

1 trial(s) available for phenylalanine and naltrexone

ArticleYear
Narcotic antagonists in drug dependence: pilot study showing enhancement of compliance with SYN-10, amino-acid precursors and enkephalinase inhibition therapy.
    Medical hypotheses, 2004, Volume: 63, Issue:3

    Topics: Adult; Aged; Amino Acids; Drug Combinations; Female; Humans; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Neprilysin; Opioid-Related Disorders; Patient Compliance; Phenylalanine; Pilot Projects; Secondary Prevention; Texas; Treatment Outcome

2004

Other Studies

16 other study(ies) available for phenylalanine and naltrexone

ArticleYear
Studies of the possible role of brain endorphins in pentobarbital anesthesia and toxicity in mice.
    Anesthesiology, 1979, Volume: 51, Issue:5

    Topics: Animals; Brain; Endorphins; Enkephalins; Leucine; Male; Mice; Morphine; Naloxone; Naltrexone; Pentobarbital; Phenylalanine

1979
Detection of alkylating agents by the analysis of amino acid residues in hemoglobin and urine. 1. The in vivo and in vitro effects of ethyl methanesulfonate, methyl methanesulfonate, hycanthone methanesulfonate, and naltrexone.
    Mutation research, 1978, Volume: 54, Issue:3

    Topics: Alkylating Agents; Amino Acid Sequence; Amino Acids; Animals; Ethyl Methanesulfonate; Hemoglobins; Histidine; Humans; Hycanthone; Male; Methyl Methanesulfonate; Naltrexone; Phenylalanine; Proline; Rats

1978
Repeated systemic administration of the mixed inhibitor of enkephalin-degrading enzymes, RB101, does not induce either antinociceptive tolerance or cross-tolerance with morphine.
    European journal of pharmacology, 1992, Nov-13, Volume: 223, Issue:1

    Topics: Analgesics; Animals; Disulfides; Dose-Response Relationship, Drug; Drug Tolerance; Indoles; Male; Mice; Morphinans; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Phenylalanine; Prodrugs; Reaction Time

1992
A selective CCKB receptor antagonist potentiates, mu-, but not delta-opioid receptor-mediated antinociception in the formalin test.
    European journal of pharmacology, 1995, Jan-24, Volume: 273, Issue:1-2

    Topics: Analgesics; Animals; Disulfides; Enkephalins; Formaldehyde; Indoles; Male; Meglumine; Mice; Morphine; Naloxone; Naltrexone; Pain Measurement; Phenylalanine; Receptors, Cholecystokinin; Receptors, Opioid, delta; Receptors, Opioid, mu

1995
CCKA, but not CCKB, agonists suppress the hyperlocomotion induced by endogenous enkephalins, protected from enzymatic degradation by systemic RB 101.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2

    Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalins; Enzyme Inhibitors; Male; Mice; Molecular Sequence Data; Motor Activity; Naltrexone; Narcotic Antagonists; Peptide Fragments; Phenylalanine; Receptors, Cholecystokinin

1995
Role of endogenous cholecystokinin in the facilitation of mu-mediated antinociception by delta-opioid agonists.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:3

    Topics: Amino Acid Sequence; Analgesia; Animals; Benzodiazepinones; Cholecystokinin; Devazepide; Disulfides; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Male; Mice; Molecular Sequence Data; Naloxone; Naltrexone; Oligopeptides; Peptide Fragments; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Sincalide

1994
[Opiatergic mechanisms of antiarrhythmic effect of adaptation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 122, Issue:9

    Topics: Adaptation, Physiological; Animals; Arrhythmias, Cardiac; Calcium Chloride; Disulfides; Endorphins; Enzyme Inhibitors; Epinephrine; Male; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Rats; Rats, Wistar; Receptors, Opioid

1996
Antidepressant-like effects of CCK(B) receptor antagonists: involvement of the opioid system.
    European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3

    Topics: Animals; Antidepressive Agents; Benzodiazepinones; Devazepide; Disulfides; Endorphins; Male; Mice; Naloxone; Naltrexone; Phenylalanine; Phenylurea Compounds; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide

1996
Involvement of delta-opioid receptors in the effects induced by endogenous enkephalins on learned helplessness model.
    European journal of pharmacology, 1998, Jul-31, Volume: 354, Issue:1

    Topics: Analgesics; Animals; Behavior, Animal; Disulfides; Drug Interactions; Enkephalins; Helplessness, Learned; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Phenylalanine; Rats; Rats, Wistar; Receptors, Opioid, delta

1998
The effects of RB101, a mixed inhibitor of enkephalin-catabolizing enzymes, on carrageenin-induced spinal c-Fos expression are completely blocked by beta-funaltrexamine, a selective mu-opioid receptor antagonist.
    Brain research, 1999, Jul-10, Volume: 834, Issue:1-2

    Topics: Animals; Carrageenan; Disulfides; Enzyme Inhibitors; Male; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Spinal Cord

1999
Enhancement of the effects of a complete inhibitor of enkephalin-catabolizing enzymes, RB 101, by a cholecystokinin-B receptor antagonist in diabetic rats.
    British journal of pharmacology, 2001, Volume: 133, Issue:1

    Topics: Aminopeptidases; Animals; Diabetes Mellitus, Experimental; Disulfides; Drug Synergism; Indoles; Male; Meglumine; Naloxone; Naltrexone; Neprilysin; Pain; Pain Measurement; Phenylalanine; Pressure; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Time Factors; Vocalization, Animal; Weight Loss

2001
Physiological control of emotion-related behaviors by endogenous enkephalins involves essentially the delta opioid receptors.
    Neuroscience, 2005, Volume: 135, Issue:2

    Topics: Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disulfides; Dose-Response Relationship, Drug; Drug Interactions; Emotions; Enkephalins; Enzyme Inhibitors; Exploratory Behavior; Freezing Reaction, Cataleptic; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Naloxone; Naltrexone; Narcotic Antagonists; Pain Measurement; Phenylalanine; Reaction Time; Receptors, Opioid, delta; Receptors, Opioid, mu; Swimming; Time Factors

2005
Behavioral and neurobiological effects of the enkephalinase inhibitor RB101 relative to its antidepressant effects.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Adrenocorticotropic Hormone; Animals; Antidepressive Agents; Behavior, Animal; Benzamides; Brain-Derived Neurotrophic Factor; Disulfides; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Frontal Lobe; Hippocampus; Injections, Intravenous; Male; Motor Activity; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Piperazines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Swimming

2006
Use of preproenkephalin knockout mice and selective inhibitors of enkephalinases to investigate the role of enkephalins in various behaviours.
    Psychopharmacology, 2008, Volume: 196, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; CD13 Antigens; Disulfides; Dose-Response Relationship, Drug; Enkephalins; Enzyme Inhibitors; Injections, Intravenous; Mice; Mice, Inbred DBA; Mice, Knockout; Morphine; Naloxone; Naltrexone; Narcotic Antagonists; Neprilysin; Phenylalanine; Protein Precursors; Swimming

2008
Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization.
    The Journal of biological chemistry, 2012, Feb-10, Volume: 287, Issue:7

    Topics: Cell Line, Tumor; Endoplasmic Reticulum; HEK293 Cells; Humans; Naltrexone; Narcotic Antagonists; Phenylalanine; Protein Multimerization; Protein Precursors; Protein Transport; Proteolysis; Receptors, Opioid, delta

2012
Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators.
    ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12

    Topics: Analgesics, Opioid; Animals; CHO Cells; Constipation; Cricetulus; Diarrhea; Drug Partial Agonism; Gastrointestinal Agents; Gastrointestinal Transit; Imidazoles; Methylation; Mice; Molecular Docking Simulation; Morphine; Naltrexone; Narcotic Antagonists; Nociception; Phenylalanine; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu

2018