phenylalanine and methyldopa

phenylalanine has been researched along with methyldopa in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199031 (83.78)18.7374
1990's1 (2.70)18.2507
2000's3 (8.11)29.6817
2010's2 (5.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cha, SH; Chairoungdua, A; Endou, H; Kanai, Y; Kim, DK; Matsuo, H1
Avdeef, A; Tam, KY1
Bellman, K; Knegtel, RM; Settimo, L1
Borison, RL; Diamond, BI; Havdala, HS; Maple, PJ1
Mosnaim, AD; Silkaitis, RP1
Loriga, M; Paglietti, G; Pinna, G; Sisini, A; Sparatore, F1
Borchardt, RT; Cortese, M; Fix, JA; Gardner, CR; Osiecka, I; Porter, PA1
Guano, G; Guilbaud, G; Menetrey, D1
Gerstenbrand, F; Gründig, E; Schedl, R; Simanyi, M; Weiss, H1
Korf, J; Postema, F; Venema, K1
Benoiton, NL; D'lorio, A; Sharma, S; Tong, JH1
Curzon, G; Green, AR1
Boyd, AE; Feldman, JM; Lebovitz, HE1
Haljasmaa, O; Ross, SB2
Zenker, N1
Ruthven, CR; Sandler, M1
Grahame-Smith, DG1
De Ropp, RS; Furst, A1
Brown, RM; Lal, H1
Goldberg, ME; Salama, AI1
Little, JM; Oliver, JH; Pirch, JH1
Chan, WC; Johnson, GE1
Nisticó, G; Preziosi, P; Scapagnini, U1
Iwao, J; Kato, E; Kawashima, Y; Matsumoto, J; Oya, M1
Gelber, LR; Neumeyer, JL1
COLLINI, FJ1
KIMURA, S; MIKUNI, M; TAKESHIMA, M1
CONTRERAS, E; CROXATTO, R; HUIDOBRO, F1
BURKARD, WP; GEY, KF; PLETSCHER, A3
JACOBY, GA; LADU, BN1
FRITEL, D; MILLIEZ, P; REY, LP1
BLAIR, W; EHRLICH, R; LAH, H; SHEFNER, A1
Borst, C; Holzgrabe, U1
Aboul-Enein, HY; Alizadeh, R; Ghassempour, A; Karami, A; Najafi, NM; Römpp, A; Spengler, B1

Reviews

2 review(s) available for phenylalanine and methyldopa

ArticleYear
The biosynthesis and metabolism of the catecholamines.
    Progress in medicinal chemistry, 1969, Volume: 6

    Topics: Alcohol Oxidoreductases; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Dopa Decarboxylase; Dopamine; Epinephrine; Humans; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Phenethylamines; Phenylalanine; Radioisotopes; Schizophrenia; Transferases; Tyrosine; Vanilmandelic Acid

1969
Progress report: the carcinoid syndrome.
    Gut, 1970, Volume: 11, Issue:2

    Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydroxyindoleacetic Acid; Kallikreins; Liver Neoplasms; Malignant Carcinoid Syndrome; Methyldopa; Methysergide; Neoplasm Metastasis; Phenoxybenzamine; Phenylalanine; Serotonin

1970

Other Studies

35 other study(ies) available for phenylalanine and methyldopa

ArticleYear
Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters.
    The Journal of biological chemistry, 2001, May-18, Volume: 276, Issue:20

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Anion Transport Proteins; Bacterial Proteins; Carrier Proteins; Cloning, Molecular; Escherichia coli Proteins; Female; Intestine, Small; Kinetics; Levodopa; Mice; Molecular Sequence Data; Oocytes; Phenylalanine; Rats; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Substrate Specificity; Tryptophan; Tyrosine; Xenopus laevis

2001
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Metabolism of an amino acid with antidepressant properties.
    Research communications in chemical pathology and pharmacology, 1978, Volume: 21, Issue:2

    Topics: Animals; Brain; Male; Methyldopa; Mice; Phenethylamines; Phenylalanine; Stereoisomerism

1978
Pathways linking L-phenylalanine and 2-phenylethylamine with p-tyramine in rabbit brain.
    Brain research, 1976, Sep-10, Volume: 114, Issue:1

    Topics: Animals; Brain; Hydrazines; Male; Methyldopa; Pargyline; Phenethylamines; Phenylalanine; Rabbits; Tyramine

1976
Synthesis of substituted DL-3(5-benzazolyl)alanines as dopa and alpha-methyldopa analogs and their effects on dopamine beta-hydroxylase, tyrosinase and diphenoloxidase.
    Farmaco (Societa chimica italiana : 1989), 1992, Volume: 47, Issue:4

    Topics: Adrenal Glands; Animals; Basidiomycota; Benzimidazoles; Catechol Oxidase; Cattle; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Fabaceae; In Vitro Techniques; Methyldopa; Monophenol Monooxygenase; Phenylalanine; Plants, Medicinal

1992
Intestinal absorption of alpha-methyldopa: in vitro mechanistic studies in rat small intestinal segments.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:2

    Topics: Amino Acids; Animal Nutritional Physiological Phenomena; Animals; Biomechanical Phenomena; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Male; Methyldopa; Osmolar Concentration; Phenylalanine; Rats; Rats, Inbred Strains; Temperature; Time Factors

1987
[Cerebral monoamines and evoked activity in the centrum medianum of the thalamus and in the primary somatic cortical area].
    Electroencephalography and clinical neurophysiology, 1971, Volume: 31, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Amphetamine; Animals; Arousal; Brain Chemistry; Cats; Cerebral Cortex; Drug Synergism; Electric Stimulation; Evoked Potentials; Injections, Intraperitoneal; Methyldopa; Nialamide; Phenylalanine; Reserpine; Sleep Stages; Thalamus

1971
[Effect of administration of amino acids, especially of L-DOPA and -methyldopa, on the composition of cerebrospinal fluid in extrapyramidal syndromes. 3. Alterations of cerebrospinal fluid in patients with Huntington's chorea after -methyldopa or L-DOPA
    Zeitschrift fur Neurologie, 1973, Mar-16, Volume: 204, Issue:1

    Topics: Adult; Aged; Alanine Transaminase; Asparagine; Aspartic Acid; Child; Dihydroxyphenylalanine; Female; Glutamates; Glutamine; Glycine; Humans; Huntington Disease; Male; Methyldopa; Middle Aged; Phenylalanine; Pyruvates; Threonine

1973
Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Autoanalysis; Brain; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Phenylalanine; Rats; Serotonin; Staining and Labeling; Stereotaxic Techniques; Time Factors

1974
A new biosynthetic pathway to catecholamines via m-tyrosine.
    Advances in neurology, 1974, Volume: 5

    Topics: Adrenal Glands; Animals; Benzyl Compounds; Brain; Carbon Radioisotopes; Catalysis; Catecholamines; Dihydroxyphenylalanine; Hydroxylation; In Vitro Techniques; Iron; Liver; Methyldopa; Methyltyrosines; Mice; Monoiodotyrosine; NADP; Phenylalanine; Phenylalanine Hydroxylase; Phosphates; Pterins; Rats; Structure-Activity Relationship; Tyrosine

1974
The effect of tryptophan metabolites on brain 5-hydroxytryptamine metabolism.
    Biochemical pharmacology, 1970, Volume: 19, Issue:6

    Topics: Alanine; Allopurinol; Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Carboxy-Lyases; Histamine; Kynurenic Acid; Kynurenine; Male; Methanol; Methyldopa; Mixed Function Oxygenases; Niacinamide; Nicotinic Acids; Nitroglycerin; ortho-Aminobenzoates; Phenylalanine; Phenylbutyrates; Picolinic Acids; Pyridines; Pyridoxal Phosphate; Pyridoxine; Rats; Serotonin; Sulfuric Acids; Time Factors; Tryptophan; Tryptophan Oxygenase; Xanthurenates

1970
Structural determinants of catecholamine action on in vitro insulin release.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 176, Issue:3

    Topics: Animals; Butyrates; Catecholamines; Cricetinae; Cyclic AMP; Dihydroxyphenylalanine; Dopamine; Epinephrine; Glucose; In Vitro Techniques; Insulin; Insulin Secretion; Isoproterenol; Methyldopa; Norepinephrine; Pancreas; Phenethylamines; Phentolamine; Phenylacetates; Phenylalanine; Phenylephrine; Structure-Activity Relationship; Tyramine; Tyrosine

1971
Inhibition of liver phenylalanine and tryptophan hydroxylating enzyme systems in vitro and in vivo.
    Acta pharmacologica et toxicologica, 1966, Volume: 24, Issue:1

    Topics: Aminopterin; Animals; Brain Chemistry; Coumarins; Enzyme Induction; Enzymes; Flavonoids; In Vitro Techniques; Liver; Liver Extracts; Methyldopa; Mice; Mixed Function Oxygenases; NAD; NADP; Phenylacetates; Phenylalanine; Rats; Serotonin; Tryptophan

1966
The interaction of pyridoxal phosphate with tyrosine analogs.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Animals; Dihydroxyphenylalanine; Dopamine; Enzymes; Epinephrine; In Vitro Techniques; Liver; Male; Methyldopa; Methyltyrosines; Normetanephrine; Octopamine; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyramine; Tyrosine; Tyrosine Transaminase; Ultraviolet Rays

1966
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
    Brain research, 1966, Volume: 2, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine

1966
A possible relationship between catecholamines and acute toxicity of desipramine.
    Psychopharmacologia, 1968, Volume: 12, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Male; Methyldopa; Mice; Mortality; Phenylalanine; Reserpine

1968
Effect of alpha-methyltyrosine on stress-induced changes in seizure susceptibility.
    European journal of pharmacology, 1970, Volume: 9, Issue:2

    Topics: Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Disulfiram; Male; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Phenylalanine; Reserpine; Seizures; Stress, Physiological; Tetrabenazine; Time Factors; Tyrosine

1970
Effect of reserpine and other drugs on the CNS and lethal effects of hyperbaric oxygen in mice.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 183, Issue:2

    Topics: Animals; Central Nervous System; Electroshock; Hyperbaric Oxygenation; Methods; Methyldopa; Methyltyrosines; Mice; Phenoxybenzamine; Phenylalanine; Phenytoin; Reserpine; Seizures; Tranylcypromine

1970
Influence of cold exposure on catecholamine depleting actions of hydroxylase inhibitors.
    European journal of pharmacology, 1968, Volume: 3, Issue:1

    Topics: Adaptation, Physiological; Adrenal Glands; Adrenal Medulla; Adrenalectomy; Animals; Cold Temperature; Epinephrine; Liver; Male; Methyldopa; Methyltyrosines; Mixed Function Oxygenases; Myocardium; Norepinephrine; Phenylalanine; Rats; Spleen; Time Factors; Tyrosine

1968
Brain serotonin depletors and adrenocortical activation.
    Biochemical pharmacology, 1968, Volume: 17, Issue:7

    Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Pressure; Corticosterone; Male; Methyldopa; Phenylalanine; Prenylamine; Rats; Stimulation, Chemical; Time Factors

1968
Thiol compounds. III Synthesis and antihypertensive activity of mercaptoacylamino acids.
    Chemical & pharmaceutical bulletin, 1981, Volume: 29, Issue:5

    Topics: Amino Acids; Animals; Antihypertensive Agents; Dihydroxyphenylalanine; Methyldopa; Phenylalanine; Sulfhydryl Compounds; Tyrosine

1981
Determination of the enantiomeric purity of levodopa, methyldopa, carbidopa and tryptophan by use of chiral mobile phase high-performance liquid chromatography.
    Journal of chromatography, 1983, Mar-04, Volume: 257, Issue:2

    Topics: Capsules; Carbidopa; Chromatography, High Pressure Liquid; Copper; Copper Sulfate; Drug Contamination; Levodopa; Methyldopa; Phenylalanine; Stereoisomerism; Tablets; Tryptophan

1983
Use of alpha-methyl-dopa (alpha-methyl-3,4-dihydroxy-DL-phenylalanine) in the management of the carcinoid syndrome.
    The New England journal of medicine, 1961, May-11, Volume: 264

    Topics: Dihydroxyphenylalanine; Disease Management; Humans; Lyases; Malignant Carcinoid Syndrome; Methyldopa; Phenylalanine

1961
[TRIALS OF A NEW ANTIHYPERTENSIVE, ALPHA-METHYL-DOPA (ALDOMET) WITH SPECIAL REFERENCE TO CHANGES IN RETINAL BLOOD FLOW].
    Rinsho ganka. Japanese journal of clinical ophthalmology, 1963, Volume: 17

    Topics: Angiotensins; Antihypertensive Agents; Blood Circulation; Blood Pressure; Blood Pressure Determination; Dopamine; Epinephrine; Hemodynamics; Methyldopa; NAD; Norepinephrine; Phenylalanine; Renin; Retinal Vessels; Serotonin; Tryptophan; Tyrosine

1963
STUDIES ON MORPHINE. III. ACTION OF METABOLIC PRECURSORS TO SEROTONIN AND NORADRENALINE AND RELATED SUBSTANCES ON THE "ABSTINENCE SYNDROME" TO MORPHINE ON WHITE MICE.
    Archives internationales de pharmacodynamie et de therapie, 1963, Dec-01, Volume: 146

    Topics: Brain; Catecholamines; Dihydroxyphenylalanine; Ergot Alkaloids; Iproniazid; Kynurenine; Lysergic Acid Diethylamide; Methyldopa; Mice; Morphine; Nalorphine; Norepinephrine; ortho-Aminobenzoates; Pharmacology; Phenylalanine; Research; Serotonin; Shikimic Acid; Toxicology; Tryptophan; Tyrosine

1963
INHIBITION OF THE HYDROXYLATION OF TRYPTOPHAN AND PHENYLALANINE BY ALPHA-METHYL-DOPA AND SIMILAR COMPOUNDS.
    Life sciences (1962), 1964, Volume: 3

    Topics: Antihypertensive Agents; Carboxy-Lyases; Enzyme Inhibitors; Hydroxylation; Liver; Metabolism; Methyldopa; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Rats; Research; Research Design; Tissue Culture Techniques; Tryptophan; Tyrosine

1964
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase

1964
[INHIBITION OF TRYPTOPHAN HYDROXYLASE BY ALPHA-METHYLDOPA].
    Helvetica physiologica et pharmacologica acta, 1964, Volume: 22

    Topics: Amino Acids; Enzyme Inhibitors; Methyldopa; Mixed Function Oxygenases; Phenylalanine; Tryptophan; Tryptophan Hydroxylase

1964
INHIBITORS OF THE ENZYMATIC HYDROXYLATION OF PHENYLALANINE AND TRYPTOPHAN BY RAT LIVER EXTRACT IN VITRO.
    Life sciences (1962), 1964, Volume: 3

    Topics: Enzyme Inhibitors; Hydroxylation; In Vitro Techniques; Liver; Liver Extracts; Methyldopa; Mixed Function Oxygenases; Pharmacology; Phenylalanine; Research; Tryptophan

1964
[CLINICAL TRIAL OF A HYPOTENSIVE DRUG: 3,4-DIHYDROXY-D-L-PHENYLALANINE OR METHYLDOPA].
    La Presse medicale, 1964, Oct-17, Volume: 72

    Topics: Antihypertensive Agents; Chlorothiazide; Chlorthalidone; Eye Manifestations; Humans; Hydrochlorothiazide; Hypertension; Hypertension, Malignant; Hypotension; Hypotension, Orthostatic; Methyldopa; Phenylalanine; Toxicology

1964
COMBINED TOXICITY OF STAPHYLOCOCCAL ENTEROTOXIN AND ALPHA-METHYL-3,4-DIHYDROXY-1-PHENYLALANINE (METHYL-DOPA).
    Nature, 1964, Jun-20, Volume: 202

    Topics: Endotoxins; Enterotoxins; Methyldopa; Mice; Phenylalanine; Research; Staphylococcal Infections; Staphylococcus; Toxicology

1964
[ALPHA,BETA,BETA-TRIMETHYLDOPA, A NEW INHIBITOR OF TRYPTOPHAN AND PHENYLALANINE HYDROXYLASE].
    Helvetica physiologica et pharmacologica acta, 1964, Volume: 64

    Topics: Amides; Amino Acids; Enzyme Inhibitors; Liver; Methyldopa; Mixed Function Oxygenases; Norepinephrine; Pharmacology; Phenylalanine; Phenylalanine Hydroxylase; Rats; Research; Serotonin; Tryptophan

1964
Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography.
    Journal of chromatography. A, 2008, Sep-19, Volume: 1204, Issue:2

    Topics: Amino Acids, Aromatic; Chromatography; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Dihydroxyphenylalanine; Hydrogen-Ion Concentration; Methyldopa; Phenylalanine; Reproducibility of Results; Stereoisomerism; Tyrosine

2008
Crystalline degradation products of vancomycin as chiral stationary phase in microcolumn liquid chromatography.
    Journal of separation science, 2008, Volume: 31, Issue:13

    Topics: Alanine; Atropine; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crystallization; Methyldopa; Microchemistry; Particle Size; Phenylalanine; Propranolol; Silicon Dioxide; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Vancomycin

2008