phenylalanine and indomethacin

phenylalanine has been researched along with indomethacin in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19909 (36.00)18.7374
1990's11 (44.00)18.2507
2000's2 (8.00)29.6817
2010's3 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bundgaard, H; Nielsen, NM1
Avdeef, A; Tam, KY1
Bellman, K; Knegtel, RM; Settimo, L1
Becker, EL; O'Flaherty, JT; Showell, HJ; Ward, PA1
Cornish, J; Gray, DH; Lowe, C; Reid, IR; Skinner, SJ1
Grun, JL; Liu, DC; Maurer, PH1
Banerjee, AK; Peters, TJ; Preedy, VR1
Banerjee, AK; Marway, JS; Peters, TJ; Preedy, VR1
Cornish, J; Gearing, DP; Hilton, DJ; Lowe, C; Martin, TJ; Reid, LR; Skinner, SJ; Willson, TA1
Hallbrucker, C; Lang, F; Rehwald, W1
Lang, F; Rehwald, W1
Collier, HO; Francis, DL; Schneider, C1
Dawkins, PD; McArthur, JN; Smith, MJ1
Brown, JH; Mackey, HK1
Palmer, RM; Reeds, PJ; Smith, RH1
Sancilio, LF; Sleevi, MC; Walsh, DA1
Pardal, JF1
Crimmin, MJ; DiMartino, MJ; Galloway, WA; High, W1
Chromiak, JA; Vandenburgh, HH1
Fujimori, Y; Katsuura, Y; Nakamura, T; Okamoto, S; Shimizu, K; Wanaka, K; Yamamuro, T1
Doualla-Bell, F; Gaudreault, RC; Guay, JM; Lévesque, D; Marceau, F; Poyet, P; Ritchot, N1
LaPointe, MC; Marsh, JD; Ritchie, RH; Schiebinger, RJ1
Min, L; Sim, MK; Xu, XG1
Breyer, RM; Hata, AN; Lybrand, TP1
Grohganz, H; Laitinen, R; Löbmann, K; Rades, T; Strachan, C1

Other Studies

25 other study(ies) available for phenylalanine and indomethacin

ArticleYear
Esters of N,N-disubstituted 2-hydroxyacetamides as a novel highly biolabile prodrug type for carboxylic acid agents.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:3

    Topics: Acetamides; Biotransformation; Carboxylic Acids; Half-Life; Humans; Indicators and Reagents; Kinetics; Structure-Activity Relationship

1987
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Role of arachidonic acid derivatives in neutrophil aggregation: a hypothesis.
    Prostaglandins, 1979, Volume: 17, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Buffers; Cell Aggregation; Chemotactic Factors; Chemotaxis, Leukocyte; Humans; Indomethacin; Neutrophils; Phenylalanine; Prostaglandin Antagonists

1979
Adenylate cyclase blockers dissociate PTH-stimulated bone resorption from cAMP production.
    The American journal of physiology, 1990, Volume: 258, Issue:4 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenylyl Cyclase Inhibitors; Animals; Bone and Bones; Bone Resorption; Calcium; Cyclic AMP; Dideoxyadenosine; DNA Replication; In Vitro Techniques; Indomethacin; Isomerism; Kinetics; Mice; Parathyroid Hormone; Phenylalanine; Protein Biosynthesis; Theophylline

1990
Enhanced proliferation of murine T cell lines following interaction of poly(Glu60,Phe40) (GPhe) and antigen-presenting accessory cells. II. The role of accessory cells and cytokines in the activity of GPhe on antigen-independent proliferation.
    Cellular immunology, 1990, Volume: 129, Issue:1

    Topics: Animals; Antigen-Presenting Cells; Culture Media; Histocompatibility Antigens Class II; Indomethacin; Interleukin-1; Interleukin-2; Interleukin-4; Interleukin-6; Interleukin-7; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Peptides; Phenylalanine; Polyglutamic Acid; Spleen; T-Lymphocytes; Tumor Necrosis Factor-alpha

1990
Selective increases in type II muscle protein synthesis in NSAID induced inflammatory bowel disease (IBD).
    Biochemical Society transactions, 1991, Volume: 19, Issue:2

    Topics: Animals; Indomethacin; Inflammatory Bowel Diseases; Kinetics; Male; Muscle Proteins; Muscles; Organ Specificity; Phenylalanine; Rats; Rats, Inbred Strains

1991
Gut protein synthetic studies in a NSAID model of inflammatory bowel disease (IBD).
    Biochemical Society transactions, 1991, Volume: 19, Issue:2

    Topics: Animals; Duodenum; Ileitis; Ileum; Indomethacin; Inflammatory Bowel Diseases; Intestinal Mucosa; Kinetics; Male; Phenylalanine; Proteins; Rats; Rats, Inbred Strains

1991
Leukemia inhibitory factor: a novel bone-active cytokine.
    Endocrinology, 1990, Volume: 126, Issue:3

    Topics: Animals; Biological Factors; Bone and Bones; Bone Resorption; Calcium; Cytokines; Dose-Response Relationship, Drug; Growth Inhibitors; Humans; Indomethacin; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Mice; Phenylalanine; Skull; Thymidine

1990
Influence of mepacrine, indomethacin, and nordihydroguaiaretic acid on the electrical properties of frog renal proximal tubules.
    Pflugers Archiv : European journal of physiology, 1990, Volume: 416, Issue:6

    Topics: Animals; Carrier Proteins; Cell Membrane; Electric Conductivity; Indomethacin; Kidney Tubules, Proximal; Masoprocol; Membrane Potentials; Perfusion; Phenylalanine; Quinacrine; Rana esculenta; Sodium-Hydrogen Exchangers

1990
On the nature of delayed repolarization during sustained sodium coupled transport in frog proximal tubules.
    Pflugers Archiv : European journal of physiology, 1987, Volume: 410, Issue:4-5

    Topics: Animals; In Vitro Techniques; Indomethacin; Kidney Tubules, Proximal; Membrane Potentials; Microelectrodes; Perfusion; Phenylalanine; Quinacrine; Rana esculenta; Sodium; Trifluoperazine

1987
Modification of morphine withdrawal by drugs interacting with humoral mechanisms: some contradictions and their interpretation.
    Nature, 1972, May-26, Volume: 237, Issue:5352

    Topics: Animals; Atropine; Behavior, Animal; Drug Interactions; Fenclonine; Heroin; Humans; Indomethacin; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Morphine; Motor Activity; Naloxone; Phenylalanine; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Time Factors

1972
The displacement of L-tryptophan and dipeptides from bovine albumin in vitro and from human plasma in vivo by antirheumatic drugs.
    The Journal of pharmacy and pharmacology, 1971, Volume: 23, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Proteins; Cattle; Chloroquine; Dipeptides; Gold; Humans; Indomethacin; Phenylalanine; Phenylbutazone; Prednisolone; Protein Binding; Salicylates; Serum Albumin, Bovine; Tryptophan

1971
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 128, Issue:1

    Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine

1968
Protein synthesis in isolated rabbit forelimb muscles. The possible role of metabolites of arachidonic acid in the response to intermittent stretching.
    The Biochemical journal, 1983, Jul-15, Volume: 214, Issue:1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; In Vitro Techniques; Indomethacin; Meclofenamic Acid; Muscle Contraction; Muscle Proteins; Muscles; Phenylalanine; Prostaglandins; Rabbits; SRS-A; Succinylcholine

1983
Antiinflammatory activity of N-(2-benzoylphenyl)alanine derivatives.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chemical Phenomena; Chemistry; Disease Models, Animal; Indicators and Reagents; Indomethacin; Phenylalanine; Pleurisy; Rats; Structure-Activity Relationship

1984
Dextro-phenylalanine inhibits potassium-evoked 3H-noradrenaline release from hypothalamus but not of 3H-dopamine from rat caudate nucleus.
    Journal of neuroscience research, 1980, Volume: 5, Issue:2

    Topics: Animals; Aspirin; Calcium; Caudate Nucleus; Dopamine; Hypothalamus; In Vitro Techniques; Indomethacin; Male; Norepinephrine; Occipital Lobe; Phenylalanine; Potassium; Prostaglandins; Rats

1980
Preclinical antiarthritic activity of matrix metalloproteinase inhibitors.
    Annals of the New York Academy of Sciences, 1994, Sep-06, Volume: 732

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Indomethacin; Inflammation; Isomerism; Metalloendopeptidases; Phenylalanine; Radiography; Rats; Thiophenes; Time Factors

1994
Mechanical stimulation of skeletal muscle cells mitigates glucocorticoid-induced decreases in prostaglandin production and prostaglandin synthase activity.
    Journal of cellular physiology, 1994, Volume: 159, Issue:3

    Topics: Animals; Cells, Cultured; Chick Embryo; Dexamethasone; Dinoprost; Dinoprostone; Indomethacin; Kinetics; Muscle Contraction; Muscle Proteins; Muscle Relaxation; Muscles; Phenylalanine; Physical Stimulation; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Time Factors

1994
Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice.
    Agents and actions, 1993, Volume: 39, Issue:1-2

    Topics: Animals; Arthritis, Experimental; Collagen; Indomethacin; Kallikreins; Kininogens; Male; Mice; Mice, Inbred DBA; Phenylalanine; Prekallikrein; Tranexamic Acid

1993
Down-regulation of interleukin-1beta production and PGE2 accumulation by an indomethacin-phenylalanine derivative in human monocytes.
    Life sciences, 1998, Volume: 62, Issue:24

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Humans; Indomethacin; Interleukin-1; Isoenzymes; Lipopolysaccharides; Membrane Proteins; Monocytes; Phenylalanine; Prostaglandin-Endoperoxide Synthases

1998
Angiotensin II-induced hypertrophy of adult rat cardiomyocytes is blocked by nitric oxide.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Angiotensin II; Animals; Bradykinin; Cardiomegaly; Cells, Cultured; Coculture Techniques; Cyclic GMP; Endothelium, Vascular; Heart; Iloprost; Indomethacin; Male; Molsidomine; Myocardium; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; omega-N-Methylarginine; Phenylalanine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley

1998
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
    Regulatory peptides, 2000, Nov-24, Volume: 95, Issue:1-3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Thoracic; Cells, Cultured; DNA; Imidazoles; Indomethacin; Losartan; Muscle, Smooth, Vascular; Myocardium; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Thymidine

2000
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
    The Journal of biological chemistry, 2005, Sep-16, Volume: 280, Issue:37

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamic Acid; Humans; Hypersensitivity; Indomethacin; Inflammation; Kinetics; Ligands; Mice; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Tyrosine

2005
Amino acids as co-amorphous stabilizers for poorly water-soluble drugs--Part 2: molecular interactions.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2013, Volume: 85, Issue:3 Pt B

    Topics: Amino Acids; Carbamazepine; Catalytic Domain; Chemistry, Pharmaceutical; Drug Stability; Excipients; Hydrogen Bonding; Indomethacin; Molecular Weight; Phenylalanine; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; Tryptophan

2013