phenylalanine and hydroxyl radical

phenylalanine has been researched along with hydroxyl radical in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.00)18.7374
1990's20 (40.00)18.2507
2000's20 (40.00)29.6817
2010's6 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gassmann, W; Gelvan, D; Hegenauer, J; Moreno, V; Saltman, P1
Koppenol, WH; Maskos, Z; Rush, JD1
Bergtold, DS; Karam, LR; Simic, MG1
Karam, LR; Simic, MG1
Farahani, M; Simic, MG1
Fagerheim, I; Grootveld, M; Halliwell, B; Kaur, H; Puppo, A1
Cross, CE; Eiserich, JP; Halliwell, B; Van der Vliet, A1
Halliwell, B; Kaur, H2
Liu, D1
Cross, CE; Halliwell, B; Kaur, H; O'Neill, CA; van der Vliet, A1
Bolli, R; Halliwell, B; Kaur, H; Li, XY; Sun, JZ1
Fujimoto, S; Kawakami, N; Ohara, A1
Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Pennathur, S; Rasmussen, JE1
Blake, DR; Edmonds, SE; Halliwell, B; Kaur, H1
Halliwell, B; Kaur, H; Whiteman, M1
Duong, DK; Miller, AF; Sorkin, DL1
Hayde, M; Lubec, G; Menzel, D; Pollak, A; Widness, JA1
Bocarsly, JR; Buranaprapuk, A; Kumar, CV; Leach, SP1
Gudelsky, GA; Shankaran, M; Yamamoto, BK1
Fujimoto, S; Hayakawa, T; Kawakami, N; Shimohama, S1
Halliwell, B; Jones, AD; Longhurst, JC; Reddy, S1
Bohannon, KE; Bruner, MW; Evans, RK; Volkin, DB; Wang, B; Xu, Z1
Anderson, VE; Chen, YH; Goshe, MB1
Adelstein, SJ; Mee, LK1
Li, Y; Wavak, D; Wolf, ME; Xue, CJ1
Ambrosio, G; Biondi, R; Paolocci, N; Rossi, R; Xia, Y; Zweier, JL1
Ferger, B; Kuschinsky, K; Teismann, P; Themann, C1
Chance, MR; Downard, KM; Kiselar, JG; Maleknia, SD; Sullivan, M1
Almo, S; Chance, M; Goldsmith, SC; Guan, JQ1
Huycke, MM; Moore, DR1
CHARRIER, JP; CIER, A; NOFRE, C1
Carlson, S; Kinzer, JA; Li, M; Perpall, HJ1
Anderson, VE; Nukuna, BN; Sun, G1
Ceballos, G; Guzman-Grenfell, AM; Hicks, JJ; Olivares-Corichi, IM; Ortega-Camarillo, C1
Fang, CX; Ontko, AC; Palanichamy, K; Rao, MN; Ren, J; Sreejayan, N; Yang, X1
Byun, J; Danda, R; Heinecke, JW; Heller, JI; Ido, Y; Pennathur, S; Pergola, P; Williamson, JR1
Bian, ZY; Du, JO; Guo, XQ; Zhao, YB1
Kó Szegi, T; Kocsis, B; Laczy, B; Markó, L; Matus, Z; Mazák, I; Mohás, M; Molnár, GA; Nagy, J; Tamaskó, M; Wagner, L; Wagner, Z; Wittmann, I1
Biró, Z; Ludány, A; Molnár, GA; Nemes, V; Wagner, Z; Wittmann, I1
Ambrosio, G; Bettini, M; Biondi, R; Cardounel, AJ; Liebgott, T; Tritto, I; Zweier, JL1
Changchien, L; Honts, JE; Hyatt, DC; Maley, F; Maley, GF; Montfort, WR; Roberts, SA1
Dennis, DM; Glushakov, AV; Gravenstein, N; Martynyuk, AE; Seubert, CN; Sumners, C; Yarotskyy, V1
Aguar, M; Arduini, A; Asensi, MA; Brugada, M; Escrig, R; Ledo, A; Saenz, P; Sastre, J; Vento, M1
Liu, R; Sun, F; Tian, Y; Wang, M; Zhang, P; Zong, W1
Matxain, JM; Mujika, JI; Uranga, J1
Giblin, D; Gross, ML; Niu, B; Rempel, DL; Zhang, H1
Bogár, L; Csontos, C; Kun, S; Miseta, A; Molnár, GA; Sélley, E; Szélig, L; Wittmann, I1
Chen, HT; Khoo, SK; Lin, YC; Wu, CC1
Biondi, R; Bottiglieri, L; Brancorsini, S; Brillo, E; Capodicasa, E; Cretoiu, D; Egidi, MG; Gerli, S; Micu, R; Poli, G; Renzo, GCD; Suciu, N1

Reviews

3 review(s) available for phenylalanine and hydroxyl radical

ArticleYear
Biomarkers of OH radical damage in vivo.
    Free radical research communications, 1991, Volume: 12-13 Pt 1

    Topics: Biomarkers; DNA; Free Radicals; Hydroxides; Hydroxyl Radical; Hydroxylation; Phenylalanine; Proteins; Thymine; Thymine Nucleotides; Tyrosine

1991
Hydroxylation of salicylate and phenylalanine as assays for hydroxyl radicals: a cautionary note visited for the third time.
    Free radical research, 1997, Volume: 27, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Hydroxylation; Phenylalanine; Salicylates; Salicylic Acid

1997
Halogenated derivatives of aromatic amino acids exhibit balanced antiglutamatergic actions: potential applications for the treatment of neurological and neuropsychiatric disorders.
    Recent patents on CNS drug discovery, 2006, Volume: 1, Issue:3

    Topics: Animals; Brain; Brain Diseases; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Hydroxyl Radical; Mental Disorders; Neuroprotective Agents; Phenylalanine; Synaptic Transmission; Tyrosine

2006

Other Studies

47 other study(ies) available for phenylalanine and hydroxyl radical

ArticleYear
Metal-ion-directed site-specificity of hydroxyl radical detection.
    Biochimica et biophysica acta, 1992, Apr-22, Volume: 1116, Issue:2

    Topics: Ascorbic Acid; Binding, Competitive; Cell-Free System; Chromatography, High Pressure Liquid; Copper; Erythrocyte Membrane; Free Radical Scavengers; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Indicators and Reagents; Kinetics; Phenylalanine; Salicylates; Salicylic Acid

1992
The hydroxylation of phenylalanine and tyrosine: a comparison with salicylate and tryptophan.
    Archives of biochemistry and biophysics, 1992, Aug-01, Volume: 296, Issue:2

    Topics: Chelating Agents; Dihydroxyphenylalanine; Gamma Rays; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Iron; Kinetics; Macromolecular Substances; Oxidation-Reduction; Phenylalanine; Pulse Radiolysis; Salicylates; Salicylic Acid; Tryptophan; Tyrosine

1992
Formation of ortho-tyrosine by radiation and organic solvents in chicken tissue.
    The Journal of biological chemistry, 1990, Jul-15, Volume: 265, Issue:20

    Topics: Animals; Cattle; Chickens; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Free Radicals; Hydroxides; Hydroxyl Radical; Mass Spectrometry; Muscles; Phenylalanine; Solvents; Tyrosine

1990
Hydroxyl radical induced cross-linking between phenylalanine and 2-deoxyribose.
    Biochemistry, 1988, Jun-28, Volume: 27, Issue:13

    Topics: Deoxyribose; Free Radicals; Gas Chromatography-Mass Spectrometry; Hydroxides; Hydroxyl Radical; Mass Spectrometry; Phenylalanine

1988
Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals: application to activated human neutrophils and to the heme protein leghemoglobin.
    Analytical biochemistry, 1988, Aug-01, Volume: 172, Issue:2

    Topics: Chromatography, High Pressure Liquid; Free Radicals; Hemeproteins; Humans; Hydroxides; Hydroxyl Radical; Hydroxylation; Leghemoglobin; Neutrophils; Phenylalanine; Tyrosine

1988
Modification of aromatic amino acids by reactive nitrogen species.
    Biochemical Society transactions, 1995, Volume: 23, Issue:2

    Topics: Free Radicals; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Mannitol; Nitrates; Nitric Oxide; Nitrogen Dioxide; Nitrogen Oxides; Oxidants; Phenylalanine; Tyrosine

1995
Aromatic hydroxylation of phenylalanine as an assay for hydroxyl radicals. Measurement of hydroxyl radical formation from ozone and in blood from premature babies using improved HPLC methodology.
    Analytical biochemistry, 1994, Volume: 220, Issue:1

    Topics: Catalysis; Chromatography, High Pressure Liquid; Fetal Blood; Humans; Hydroxyl Radical; Hydroxylation; Infant, Newborn; Infant, Premature; Molecular Structure; Ozone; Phenylalanine; Solutions; Stereoisomerism; Water

1994
Generation and detection of hydroxyl radical in vivo in rat spinal cord by microdialysis administration of Fenton's reagents and microdialysis sampling.
    Journal of biochemical and biophysical methods, 1993, Volume: 27, Issue:4

    Topics: Animals; Dialysis; Edetic Acid; Ferrous Compounds; Hydrogen Peroxide; Hydroxyl Radical; Iron; Male; Phenylalanine; Rats; Rats, Sprague-Dawley; Spinal Cord

1993
Aromatic hydroxylation and nitration of phenylalanine and tyrosine by peroxynitrite. Evidence for hydroxyl radical production from peroxynitrite.
    FEBS letters, 1994, Feb-14, Volume: 339, Issue:1-2

    Topics: Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Serum Albumin, Bovine; Thermodynamics; Tyrosine; Uric Acid

1994
Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning.
    Circulation research, 1993, Volume: 73, Issue:3

    Topics: Animals; Antioxidants; Coronary Circulation; Dogs; Female; Hydroxides; Hydroxyl Radical; Hydroxylation; Male; Myocardial Infarction; Myocardium; Phenylalanine; Tyrosine

1993
Formation of a hydroxyl radical by the myeloperoxidase-NADH-oxygen system.
    Biological & pharmaceutical bulletin, 1993, Volume: 16, Issue:6

    Topics: Aerobiosis; Catalase; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydroxides; Hydroxyl Radical; Hydroxylation; Kinetics; NAD; Oxygen; Peroxidase; Phenylalanine; Superoxide Dismutase; Tyrosine

1993
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
    The Journal of biological chemistry, 1997, Feb-07, Volume: 272, Issue:6

    Topics: Animals; Aorta; Arteriosclerosis; Cattle; Copper; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyl Radical; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine

1997
Hydroxyl radical generation by rheumatoid blood and knee joint synovial fluid.
    Annals of the rheumatic diseases, 1996, Volume: 55, Issue:12

    Topics: Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Knee Joint; Phenylalanine; Synovial Fluid; Tyrosine

1996
Peroxynitrite-dependent aromatic hydroxylation and nitration of salicylate and phenylalanine. Is hydroxyl radical involved?
    Free radical research, 1997, Volume: 26, Issue:1

    Topics: Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Nitrates; Phenylalanine; Salicylates; Salicylic Acid

1997
Mutation of tyrosine 34 to phenylalanine eliminates the active site pK of reduced iron-containing superoxide dismutase.
    Biochemistry, 1997, Jul-08, Volume: 36, Issue:27

    Topics: Binding Sites; Electrochemistry; Electron Spin Resonance Spectroscopy; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyl Radical; Iron; Magnetic Resonance Spectroscopy; Mutation; Oxidation-Reduction; Phenylalanine; Superoxide Dismutase; Tyrosine

1997
Hydroxyl radical generation in oxygen-treated infants.
    Pediatrics, 1997, Volume: 100, Issue:4

    Topics: Apgar Score; Dose-Response Relationship, Drug; Humans; Hydroxyl Radical; Infant, Newborn; Infant, Newborn, Diseases; Oxygen; Oxygen Inhalation Therapy; Phenylalanine; Regression Analysis; Tyrosine

1997
Protein cleavage by transition metal complexes bearing amino acid substituents.
    Biochimica et biophysica acta, 1998, Sep-08, Volume: 1387, Issue:1-2

    Topics: Amino Acids; Binding Sites; Buffers; Carboxypeptidases; Carboxypeptidases A; Copper; Electrophoresis, Polyacrylamide Gel; Hydroxyl Radical; Iron; Kinetics; Mass Spectrometry; Metals; Phenylalanine; Serum Albumin, Bovine; Spectrophotometry; Temperature

1998
Mazindol attenuates the 3,4-methylenedioxymethamphetamine-induced formation of hydroxyl radicals and long-term depletion of serotonin in the striatum.
    Journal of neurochemistry, 1999, Volume: 72, Issue:6

    Topics: Animals; Corpus Striatum; Hydroxybenzoates; Hydroxyl Radical; Kinetics; Male; Mazindol; Microdialysis; N-Methyl-3,4-methylenedioxyamphetamine; Phenylalanine; Rats; Rats, Sprague-Dawley; Salicylic Acid; Serotonin; Tyrosine

1999
The hydroxyl radical formation system in polymorphonuclear leukocytes.
    Biological & pharmaceutical bulletin, 1999, Volume: 22, Issue:10

    Topics: Animals; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Neutrophils; Peroxidase; Phenylalanine; Swine; Tyrosine

1999
The use of phenylalanine to detect hydroxyl radical production in vivo: a cautionary note.
    Free radical biology & medicine, 1999, Volume: 27, Issue:11-12

    Topics: Animals; Cats; Chromatography, High Pressure Liquid; False Positive Reactions; Hydroxyl Radical; Phenylalanine; Tyrosine

1999
Evaluation of degradation pathways for plasmid DNA in pharmaceutical formulations via accelerated stability studies.
    Journal of pharmaceutical sciences, 2000, Volume: 89, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Apurinic Acid; Buffers; Deoxyguanosine; DNA, Circular; DNA, Superhelical; Drug Stability; Drug Storage; Edetic Acid; Ethanol; Hydrogen-Ion Concentration; Hydroxyl Radical; Hydroxylation; Kinetics; Metals; Oxidation-Reduction; Phenylalanine; Phosphates; Plasmids; Predictive Value of Tests

2000
Identification of the sites of hydroxyl radical reaction with peptides by hydrogen/deuterium exchange: prevalence of reactions with the side chains.
    Biochemistry, 2000, Feb-22, Volume: 39, Issue:7

    Topics: Deuterium; Dithiothreitol; DNA Footprinting; Enkephalin, Leucine-2-Alanine; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron; Leucine; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tyrosine

2000
Inactivation of ribonuclease S-peptide by the primary aqueous radicals.
    Radiation research, 1974, Volume: 60, Issue:3

    Topics: Amino Acid Sequence; Chromatography, Gel; Gamma Rays; Hydroxyl Radical; Methionine; Molecular Sequence Data; Molecular Weight; Peptide Fragments; Phenylalanine; Protons; Ribonuclease, Pancreatic; Ribonucleases; Solutions; Water

1974
Amphetamine increases glutamate efflux in the rat ventral tegmental area by a mechanism involving glutamate transporters and reactive oxygen species.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Amino Acid Transport System X-AG; Amphetamine; Animals; ATP-Binding Cassette Transporters; Behavior, Animal; Calcium; Central Nervous System Stimulants; Cyclic N-Oxides; Free Radical Scavengers; Glutamic Acid; Hydroxyl Radical; Male; Microdialysis; Motor Activity; Neuroprotective Agents; Nitrogen Oxides; Phenylalanine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine; Ventral Tegmental Area

2000
Detection of hydroxyl radicals by D-phenylalanine hydroxylation: a specific assay for hydroxyl radical generation in biological systems.
    Analytical biochemistry, 2001, Mar-01, Volume: 290, Issue:1

    Topics: Cell Survival; Chromatography, High Pressure Liquid; Free Radicals; Humans; Hydroxyl Radical; Hydroxylation; Neutrophils; Phenylalanine; Tyrosine

2001
Comparison of two independent aromatic hydroxylation assays in combination with intracerebral microdialysis to determine hydroxyl free radicals.
    Journal of neuroscience methods, 2001, Jul-15, Volume: 108, Issue:1

    Topics: Animals; Biological Assay; Cerebral Cortex; Gentisates; Hydrocarbons, Aromatic; Hydroxyl Radical; Isomerism; Male; Microdialysis; Motor Activity; Neurons; Oxidative Stress; Oxidopamine; Phenylalanine; Rats; Rats, Wistar; Salicylic Acid; Sympatholytics

2001
Hydroxyl radical probe of protein surfaces using synchrotron X-ray radiolysis and mass spectrometry.
    International journal of radiation biology, 2002, Volume: 78, Issue:2

    Topics: Amino Acids; Biophysics; Dose-Response Relationship, Drug; Hydroxyl Radical; Mass Spectrometry; Methionine; Models, Chemical; Models, Molecular; Muramidase; Oxygen; Peptides; Phenylalanine; Protein Binding; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Trypsin; Tryptophan; X-Rays

2002
Synchrotron protein footprinting: a technique to investigate protein-protein interactions.
    Journal of biomolecular structure & dynamics, 2001, Volume: 19, Issue:3

    Topics: Actins; Amino Acid Sequence; Animals; Aspartic Acid; Binding Sites; Calcium; Gelsolin; Hydroxyl Radical; Kinetics; Macromolecular Substances; Models, Molecular; Phenylalanine; Protein Conformation; Protein Footprinting; Protein Structure, Tertiary; Proteins; Rabbits; Synchrotrons; X-Rays

2001
In vivo production of hydroxyl radical by Enterococcus faecalis colonizing the intestinal tract using aromatic hydroxylation.
    Free radical biology & medicine, 2002, Sep-15, Volume: 33, Issue:6

    Topics: Animals; Chromatography, High Pressure Liquid; Colon; Electron Spin Resonance Spectroscopy; Enterococcus faecalis; Free Radical Scavengers; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Intestines; Nitrobenzenes; Nitrogen Oxides; Oxidative Stress; Phenylalanine; Rats; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine

2002
[QUANTITATIVE STUDY OF THE FATE OF AMINO ACIDS UNDER THE INFLUENCE OF THE FREE HYDROXYL RADICAL].
    Bulletin de la Societe de chimie biologique, 1963, Oct-04, Volume: 45

    Topics: Alanine; Amino Acids; Aminobutyrates; Aspartic Acid; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Chromatography; Glutamates; Hydroxides; Hydroxyl Radical; Phenylalanine; Research; Serine; Tryptophan

1963
HPLC and LC-MS studies of hydroxylation of phenylalanine as an assay for hydroxyl radicals generated from Udenfriend's reagent.
    Biochemical and biophysical research communications, 2003, Dec-12, Volume: 312, Issue:2

    Topics: Chromatography, High Pressure Liquid; Chromatography, Liquid; Gas Chromatography-Mass Spectrometry; Hydroxyl Radical; Hydroxylation; Indicators and Reagents; Mass Spectrometry; Phenylalanine; Tyrosine

2003
Hydroxyl radical oxidation of cytochrome c by aerobic radiolysis.
    Free radical biology & medicine, 2004, Oct-15, Volume: 37, Issue:8

    Topics: Aerobiosis; Amino Acid Sequence; Animals; Cytochromes c; Dose-Response Relationship, Radiation; Electrons; Heme; Horses; Hydroxyl Radical; Hydroxylation; Intracellular Membranes; Methionine; Mitochondria, Heart; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Protein Conformation; Pulse Radiolysis; Rats; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet; Tyrosine

2004
Reactive oxygen species (ROS) induce chemical and structural changes on human insulin in vitro, including alterations in its immunoreactivity.
    Frontiers in bioscience : a journal and virtual library, 2005, Jan-01, Volume: 10

    Topics: Carbon; Diabetes Mellitus; Epitopes; Formazans; Humans; Hydroxyl Radical; Insulin; Nitroblue Tetrazolium; Oxidative Stress; Phenylalanine; Radioimmunoassay; Reactive Oxygen Species

2005
A newly synthetic chromium complex--chromium(phenylalanine)3 improves insulin responsiveness and reduces whole body glucose tolerance.
    FEBS letters, 2005, Feb-28, Volume: 579, Issue:6

    Topics: Adipocytes; Animals; Cell Line; Chromatin; DNA; Glucose; Glucose Tolerance Test; Hydroxyl Radical; Insulin; Male; Mice; Phenylalanine; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin

2005
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes.
    The Journal of biological chemistry, 2005, Jun-17, Volume: 280, Issue:24

    Topics: Amino Acids; Animals; Antioxidants; Carbon; Cerebral Cortex; Chromatography, High Pressure Liquid; Diabetes Mellitus; Diabetes Mellitus, Experimental; Fatty Acids, Unsaturated; Glucose; Guanidines; Hydroxyl Radical; Hyperglycemia; Lipid Metabolism; Lipid Peroxidation; Lipoproteins, LDL; Male; Mass Spectrometry; Oxidative Stress; Oxygen; Phenylalanine; Rats; Rats, Sprague-Dawley; Retina; Ribonuclease, Pancreatic; Temperature; Tyrosine

2005
Probing the hydroxyl radical-mediated reactivity of peroxynitrite by a spin-labeling fluorophore.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2005, Volume: 21, Issue:5

    Topics: Carbon Dioxide; Chromatography, High Pressure Liquid; Dimethyl Sulfoxide; Fluorescent Dyes; Formates; Histidine; Hydrogen-Ion Concentration; Hydroxyl Radical; Indicators and Reagents; Peroxynitrous Acid; Phenylalanine; Reproducibility of Results; Solvents; Spectrometry, Fluorescence; Spin Labels; Tyrosine

2005
Urinary ortho-tyrosine excretion in diabetes mellitus and renal failure: evidence for hydroxyl radical production.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: Aged; Cross-Sectional Studies; Diabetic Nephropathies; Female; Humans; Hydroxyl Radical; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Phenylalanine; Tyrosine

2005
Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase.
    Free radical research, 2005, Volume: 39, Issue:12

    Topics: Aged; Cataract; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dihydroxyphenylalanine; Eye Proteins; Humans; Hydroxyl Radical; Lens, Crystalline; Middle Aged; Phenylalanine; Solubility; Tyrosine; Water

2005
Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology.
    Cardiovascular research, 2006, Jul-15, Volume: 71, Issue:2

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydroxyl Radical; Hydroxylation; Male; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Perfusion; Phenylalanine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Tyrosine

2006
Structure of the Y94F mutant of Escherichia coli thymidylate synthase.
    Acta crystallographica. Section F, Structural biology and crystallization communications, 2006, Sep-01, Volume: 62, Issue:Pt 9

    Topics: Amino Acid Substitution; Catalytic Domain; Escherichia coli; Escherichia coli Proteins; Hydrogen Bonding; Hydroxyl Radical; Phenylalanine; Thymidylate Synthase; Tyrosine; Water

2006
Human milk enhances antioxidant defenses against hydroxyl radical aggression in preterm infants.
    The American journal of clinical nutrition, 2009, Volume: 89, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Analysis of Variance; Antioxidants; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Cohort Studies; Deoxyguanosine; DNA Damage; Female; Gestational Age; Humans; Hydroxyl Radical; Infant Formula; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Male; Milk, Human; Oxidative Stress; Phenylalanine; Reactive Oxygen Species; Tandem Mass Spectrometry

2009
A new biomarker of protein oxidation degree and site using angiotensin as the target by MS.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2010, Volume: 75, Issue:2

    Topics: Angiotensins; Biomarkers; Chromatography, High Pressure Liquid; Hydroxyl Radical; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Phenylalanine; Proteins; Tandem Mass Spectrometry; Tyrosine

2010
Computational study on the attack of ·OH radicals on aromatic amino acids.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, May-17, Volume: 19, Issue:21

    Topics: Amino Acids, Aromatic; Hydroxyl Radical; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenylalanine; Proteins; Stereoisomerism; Thermodynamics; Tryptophan; Tyrosine

2013
Dosimetry determines the initial OH radical concentration in fast photochemical oxidation of proteins (FPOP).
    Journal of the American Society for Mass Spectrometry, 2015, Volume: 26, Issue:5

    Topics: Deuterium; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Glutamine; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Indicator Dilution Techniques; Kinetics; Lasers; Methionine; Models, Molecular; Osmolar Concentration; Oxidants; Oxidation-Reduction; Phenylalanine; Photolysis; Proteins; Radiation Dosage

2015
Insulin Therapy of Nondiabetic Septic Patients Is Predicted by para-Tyrosine/Phenylalanine Ratio and by Hydroxyl Radical-Derived Products of Phenylalanine.
    Oxidative medicine and cellular longevity, 2015, Volume: 2015

    Topics: Aged; Aged, 80 and over; Carbohydrate Metabolism; Chromatography, High Pressure Liquid; Female; Glucose; Humans; Hydroxyl Radical; Insulin; Isomerism; Male; Middle Aged; Phenylalanine; Shock, Septic; Tyrosine

2015
The TFIIE-related Rpc82 subunit of RNA polymerase III interacts with the TFIIB-related transcription factor Brf1 and the polymerase cleft for transcription initiation.
    Nucleic acids research, 2018, 02-16, Volume: 46, Issue:3

    Topics: Amino Acid Sequence; Base Sequence; Benzophenones; Binding Sites; Cloning, Molecular; Cross-Linking Reagents; DNA; DNA, Fungal; Gene Expression Regulation, Fungal; Hydroxyl Radical; Models, Molecular; Phenylalanine; Plasmids; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; RNA Polymerase III; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Transcription Factor TFIIIB; Transcription Initiation, Genetic

2018
Detection and scavenging of hydroxyl radical via D-phenylalanine hydroxylation in human fluids.
    Talanta, 2018, May-01, Volume: 181

    Topics: Adult; Chocolate; Diet; Female; Free Radical Scavengers; Humans; Hydrogen Peroxide; Hydroxyl Radical; Hydroxylation; Iron; Male; Middle Aged; Milk, Human; Phenylalanine; Pregnancy; Reproducibility of Results; Semen; Thiourea; Tyrosine; Young Adult

2018