phenylalanine has been researched along with gramicidin a in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (47.73) | 18.7374 |
| 1990's | 11 (25.00) | 18.2507 |
| 2000's | 9 (20.45) | 29.6817 |
| 2010's | 3 (6.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Laland, SG; Zimmer, TL | 1 |
| Barraclough, R; Laland, S | 1 |
| Kleinkauf, H; Vater, J | 1 |
| Demain, AL; Matteo, CC | 1 |
| Demain, AL; Vandamme, EJ | 1 |
| Kawai, M; Nagai, U | 1 |
| Rae, ID; Scheraga, HA | 1 |
| Hori, K; Kanda, M; Kurotsu, T; Miura, S; Nozoe, A; Saito, Y | 1 |
| Aarstad, K; Laland, SG; Zimmer, TL | 1 |
| Andersen, OS; Koeppe, RE; Mazet, JL | 2 |
| Kossova, GV; Parkhomenko, IM; Romanova, NA; Zarubina, AP | 1 |
| Andersen, OS; Becker, MD; Greathouse, DV; Koeppe, RE | 1 |
| Higashijima, T; Kawai, M; Miyazawa, T; Nagai, U | 1 |
| Laland, SG; Pass, L; Zimmer, TL | 2 |
| Hori, K; Kanda, M; Kurotsu, T; Miura, S; Saito, Y; Yamada, Y | 1 |
| Hori, K; Kanda, M; Miura, S; Saito, Y; Yamada, Y | 1 |
| Ando, S; Aoyagi, H; Izumiya, N; Kato, T; Waki, M | 1 |
| Busath, D; Prasad, KU; Szabo, G; Trapane, TL; Urry, DW | 1 |
| Marahiel, MA; Stachelhaus, T | 1 |
| Abad, C; Bañó, MC; Braco, L; Salom, D | 1 |
| Busath, D; Seoh, SA | 1 |
| Easton, PL; Hinton, JF; Newkirk, DK; Shungu, DC | 1 |
| Agresti, M; Grizzuti, K; Gros, P; Kajiji, S; Safa, AR; Talbot, F; Van Dyke-Phillips, V | 1 |
| Brick, P; Conti, E; Marahiel, MA; Stachelhaus, T | 1 |
| Franke, P; Leenders, F; Stein, T; Vater, J | 1 |
| Abad, C; Pascal, J; Pérez-Payá, E; Salom, D | 1 |
| Stachelhaus, T; Walsh, CT | 1 |
| Luo, L; Walsh, CT | 1 |
| Burkart, MD; Luo, L; Stachelhaus, T; Walsh, CT | 1 |
| BODLEY, JW; OKUDA, K; UEMURA, I; WINNICK, T | 1 |
| EIKHOM, TS; JONSEN, J; LALAND, S; REFSVIK, T | 1 |
| BERG, TL; FROHOLM, LO; LALAND, SG | 1 |
| EIKHOM, TS; LALAND, S | 1 |
| Easton, PL; Hinton, JF; Jordan, JB | 1 |
| Higuchi, S; Katsu, T; Kawai, M; Ohmizo, C; Tanaka, R; Umemoto, H; Yamamura, H | 1 |
| Habicher, WD; Husaru, L; Salzer, R; Schulze, R; Steiner, G; Wolff, T | 1 |
| Buizert, AE; de Neeling, AJ; Grotenbreg, GM; Llamas-Saiz, AL; Noort, D; Overhand, M; Overkleeft, HS; Spalburg, E; van der Marel, GA; van Hooft, PA; van Raaij, MJ | 1 |
| Andreu, D; Cativiela, C; de la Torre, BG; Fernández-Reyes, M; Jiménez, AI; Jiménez, MA; Rivas, L; Santiveri, CM; Solanas, C | 2 |
| Busscher, HJ; Engels, E; Llamas-Saiz, AL; Mars-Groenendijk, RH; Noort, D; Otero, JM; Overhand, M; Overkleeft, HS; van der Knaap, M; van der Marel, GA; van Raaij, MJ | 1 |
| Busscher, HJ; Lageveen, LT; Llamas-Saiz, AL; Mars-Groenendijk, R; Noort, D; Otero, JM; Overhand, M; Overkleeft, HS; van der Knaap, M; van der Marel, GA; van Raaij, MJ | 1 |
| Andersen, OS; Greathouse, DV; Gu, H; Kim, JH; Koeppe, RE; Lum, K | 1 |
44 other study(ies) available for phenylalanine and gramicidin a
| Article | Year |
|---|---|
Gramicidine S synthetase.
Topics: Adenosine Triphosphate; Amino Acid Isomerases; Bacillus; Cell Division; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Culture Media; Drug Stability; Gramicidin; Kinetics; Methods; Multienzyme Complexes; Peptide Synthases; Phenylalanine | 1975 |
Gramicidin S synthetase: variations in the activites of the light and heavy enzymes with growth of culture of Bacillus brevis.
Topics: Amino Acid Isomerases; Bacillus; Gramicidin; Molecular Weight; Multienzyme Complexes; Ornithine; Peptide Synthases; Phenylalanine | 1975 |
Substrate specificity of the amino acyl adenylate activation sites of gramicidin S-synthetase (GSS).
Topics: Acetylation; Adenosine Monophosphate; Amino Acid Isomerases; Amino Acids; Bacillus; Binding Sites; Esters; Gramicidin; Leucine; Lysine; Multienzyme Complexes; Ornithine; Peptide Synthases; Phenylalanine; Proline; Stereoisomerism; Valine | 1975 |
Phenylalanine stimulation of gramicidin S formation.
Topics: Amino Acids; Bacillus; Culture Media; Gramicidin; Phenylalanine; Stimulation, Chemical; Time Factors | 1976 |
Nutrition of Bacillus brevis ATCC 9999, the producer of gramicidin S.
Topics: Bacillus; Carbon; Culture Media; Fermentation; Fructose; Glycerol; Gramicidin; Nitrogen; Phenylalanine; Phosphorus; Sulfur; Time Factors; Tromethamine | 1976 |
Comparison of conformation and antimicrobial activity of synthetic analogs of gramicidin S: Stereochemical consideration of the role of D-phenylalanine in the antibiotic.
Topics: Amino Acid Sequence; Gramicidin; Microbial Sensitivity Tests; Phenylalanine; Protein Conformation; Stereoisomerism; Structure-Activity Relationship | 1978 |
Shielding effects of the D-Phe aromatic ring in the 1H NMR spectrum of gramicidine S.
Topics: Gramicidin; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Protein Conformation; Proteins | 1978 |
Studies on gramicidin S synthetase. Purification and properties of the light enzyme obtained from some mutants of Bacillus brevis.
Topics: Amino Acid Isomerases; Aminoacylation; Bacillus; Gramicidin; Molecular Weight; Multienzyme Complexes; Mutation; Peptide Synthases; Phenylalanine; Species Specificity | 1978 |
Replacement of phenylalanine in gramicidin S by other amino acids.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Gramicidin; Phenylalanine; Tyrosine | 1979 |
Distinction between dipolar and inductive effects in modulating the conductance of gramicidin channels.
Topics: Amino Acid Sequence; Cell Membrane Permeability; Electric Conductivity; Electrochemistry; Gramicidin; Ion Channels; Molecular Sequence Data; Phenylalanine; Protein Conformation; Structure-Activity Relationship | 1990 |
[The radiobiological characteristics of the P+ variant of Bacillus brevis var. G.--B. in relation to gramicidin S synthesis].
Topics: Bacillus; Colony Count, Microbial; Depression, Chemical; Dose-Response Relationship, Radiation; Genetic Variation; Gramicidin; Phenylalanine; Radiation Tolerance; Time Factors | 1990 |
Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration.
Topics: Amino Acid Sequence; Gramicidin; Hydrogen Bonding; Ion Channels; Lipid Bilayers; Membrane Potentials; Molecular Sequence Data; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Thermodynamics; Tryptophan | 1991 |
Gramicidin S analogs with a D-Ala, Gly, or L-Ala residue in place of the D-Phe residue: molecular conformations and interactions with phospholipid membrane.
Topics: Alanine; Glycine; Gramicidin; Liposomes; Phenylalanine; Protein Conformation; Structure-Activity Relationship; Thermodynamics | 1986 |
The use of affinity chromatography in determining the sites of protein-protein interaction relative to the binding sites of substrates in gramicidin S synthetase.
Topics: Amino Acid Isomerases; Binding Sites; Chromatography, Affinity; Gramicidin; Leucine; Ligands; Multienzyme Complexes; Ornithine; Peptide Synthases; Phenylalanine; Polysaccharides; Proline; Valine | 1973 |
On the use of affinity chromatography in demonstrating the transfer of thioester-bound D-phenylalanine from the light enzyme of gramicidin S synthetase to an acceptor site for this amino acid on the heavy enzyme.
Topics: Adenosine Triphosphate; Amino Acid Isomerases; Amino Acids; Binding Sites; Biological Transport; Carbon Radioisotopes; Chromatography, Affinity; Gramicidin; Ligands; Models, Chemical; Multienzyme Complexes; Peptide Synthases; Phenylalanine; Phosphorus Radioisotopes; Protein Binding; Sulfhydryl Compounds | 1974 |
Absence of pantothenic acid in gramicidin S synthetase 2 obtained from some mutants of Bacillus brevis.
Topics: Amino Acid Isomerases; Amino Acids; Bacillus; Biological Assay; Gramicidin; Lactobacillus; Multienzyme Complexes; Mutation; Pantothenic Acid; Peptide Chain Elongation, Translational; Peptide Synthases; Phenylalanine; Piperazines | 1981 |
Transfer of D-phenylalanine from gramicidin S synthetase 1 to gramicidin S synthetase 2 in gramicidin S synthesis.
Topics: Amino Acid Isomerases; Bacillus; Binding Sites; Chromatography, Thin Layer; Gramicidin; Multienzyme Complexes; Mutation; Peptide Synthases; Phenylalanine; Structure-Activity Relationship | 1983 |
Studies of peptide antibiotics. XLIII. Syntheses of gramicidin S analogs containing D-serine or dehydroalanine in place of D-phenylalanine and asymmetric hydrogenation of the dehydroalanine residue.
Topics: Alanine; Bacteria; Gramicidin; Indicators and Reagents; Optical Rotation; Phenylalanine; Serine; Structure-Activity Relationship | 1983 |
Synthesis and characterization of (1-13C) Phe9 gramicidin A. Effects of side chain variations.
Topics: Amino Acid Sequence; Carbon Isotopes; Circular Dichroism; Gramicidin; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Conformation | 1983 |
Single-channel studies on linear gramicidins with altered amino acid sequences. A comparison of phenylalanine, tryptophane, and tyrosine substitutions at positions 1 and 11.
Topics: Amino Acid Sequence; Animals; Gramicidin; Ion Channels; Mathematics; Models, Biological; Models, Molecular; Phenylalanine; Structure-Activity Relationship; Tryptophan; Tyrosine | 1984 |
Modular structure of peptide synthetases revealed by dissection of the multifunctional enzyme GrsA.
Topics: Adenosine Triphosphate; Amino Acid Isomerases; Amino Acid Sequence; Bacillus; Base Sequence; Cloning, Molecular; Codon; Conserved Sequence; Diphosphates; DNA Primers; Gene Expression; Gramicidin; Histidine; Isomerism; Kinetics; Molecular Sequence Data; Molecular Weight; Operon; Phenylalanine; Polymerase Chain Reaction; Recombinant Proteins; Sequence Deletion; Sequence Tagged Sites | 1995 |
HPLC demonstration that an all Trp-->Phe replacement in gramicidin A results in a conformational rearrangement from beta-helical monomer to double-stranded dimer in model membranes.
Topics: Chromatography, High Pressure Liquid; Gramicidin; Ion Channels; Membrane Proteins; Membranes, Artificial; Phenylalanine; Protein Conformation; Protein Structure, Secondary; Structure-Activity Relationship; Tryptophan | 1995 |
Gramicidin tryptophans mediate formamidinium-induced channel stabilization.
Topics: Amidines; Electrophysiology; Gramicidin; Ion Channels; Kinetics; Lipid Bilayers; Macromolecular Substances; Membrane Potentials; Models, Biological; Phenylalanine; Structure-Activity Relationship; Tryptophan | 1995 |
23Na-NMR study of ion transport across vesicle membranes facilitated by phenylalanine analogs of gramicidin.
Topics: Gramicidin; Ion Transport; Magnetic Resonance Spectroscopy; Membranes; Phenylalanine; Sodium; Temperature; Tryptophan | 1993 |
Functional analysis of P-glycoprotein mutants identifies predicted transmembrane domain 11 as a putative drug binding site.
Topics: Affinity Labels; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Biological Transport; Cell Membrane; CHO Cells; Cloning, Molecular; Colchicine; Cricetinae; Dactinomycin; Doxorubicin; Drug Resistance; Gramicidin; Iodine Radioisotopes; Kinetics; Membrane Glycoproteins; Mice; Mutagenesis, Site-Directed; Phenylalanine; Prazosin; Serine; Transfection; Vinblastine | 1993 |
Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S.
Topics: Adenosine Monophosphate; Amino Acid Isomerases; Amino Acid Sequence; Animals; Bacillus; Binding Sites; Coleoptera; Crystallography, X-Ray; Gramicidin; Hydrogen Bonding; Luciferases; Models, Molecular; Molecular Sequence Data; Phenylalanine; Protein Binding; Protein Conformation; Protein Structure, Secondary; Sequence Alignment | 1997 |
Characterization of the binding site of the tripeptide intermediate D-Phenylalanyl L-prolyl-L-valine in gramicidin S biosynthesis.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Bacillus; Binding Sites; Gramicidin; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Peptide Fragments; Peptide Synthases; Phenylalanine; Proline; Serine Endopeptidases; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Staphylococcus aureus; Valine | 1998 |
Environment- and sequence-dependent modulation of the double-stranded to single-stranded conformational transition of gramicidin A in membranes.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cholestenes; Chromatography, High Pressure Liquid; Circular Dichroism; Dimerization; Enterococcus faecium; Fatty Acids, Unsaturated; Gramicidin; Lipid Bilayers; Microbial Sensitivity Tests; Molecular Sequence Data; Phenylalanine; Phosphatidylcholines; Protein Conformation; Spectrometry, Fluorescence; Tryptophan | 1998 |
Mutational analysis of the epimerization domain in the initiation module PheATE of gramicidin S synthetase.
Topics: Amino Acid Isomerases; Amino Acid Sequence; Bacillus; Carbohydrate Epimerases; Catalysis; Diketopiperazines; DNA Mutational Analysis; Electron Transport; Gramicidin; Hydrolysis; Molecular Sequence Data; Mutagenesis, Site-Directed; Pantetheine; Peptide Chain Initiation, Translational; Phenylalanine; Piperazines; Protein Structure, Tertiary; Sequence Homology, Amino Acid | 2000 |
Kinetic analysis of three activated phenylalanyl intermediates generated by the initiation module PheATE of gramicidin S synthetase.
Topics: Adenosine Monophosphate; Alanine; Amino Acid Isomerases; Amino Acid Motifs; Aminoacylation; Apoenzymes; Bacillus; Carbon Radioisotopes; Catalysis; Gramicidin; Histidine; Holoenzymes; Kinetics; Mutagenesis, Site-Directed; Pantetheine; Peptide Chain Initiation, Translational; Phenylalanine; Protein Structure, Tertiary | 2001 |
Substrate recognition and selection by the initiation module PheATE of gramicidin S synthetase.
Topics: Adenosine Monophosphate; Adenosine Triphosphate; Amino Acid Isomerases; Amino Acids; Aminoacylation; Apoenzymes; Gramicidin; Kinetics; Peptide Chain Initiation, Translational; Phenylalanine; Protein Structure, Tertiary; Spectrometry, Fluorescence; Substrate Specificity; Thermodynamics | 2001 |
EXPERIMENTS ON THE MECHANISM OF GRAMICIDIN AND TYROCIDINE SYNTHESIS IN CELL-FREE PREPARATIONS ON BACILLUS BREVIS.
Topics: Bacillus; Carbon Isotopes; Chemistry Techniques, Analytical; Diphosphates; Glutamates; Glutamine; Gramicidin; Leucine; Peptides; Phenylalanine; Proteins; Research; RNA; RNA, Bacterial; Tritium; Tyrocidine; Tyrothricin; Valine | 1964 |
STUDIES ON THE BIOSYNTHESIS OF GRAMICIDIN S IN WHOLE CELLS OF BACILLUS BREVIS.
Topics: Bacillus; Carbon Isotopes; Chloramphenicol; Chromatography; Gramicidin; Metabolism; Mitomycin; Mitomycins; Ornithine; Pharmacology; Phenylalanine; Proteins; Research; Spectrophotometry; Tyrothricin | 1964 |
THE BIOSYNTHESIS OF GRAMICIDIN S IN A CELL-FREE SYSTEM.
Topics: Adenosine Triphosphate; Amino Acids; Bacillus; Carbon Isotopes; Cell-Free System; Chloramphenicol; Gramicidin; Hydrogen-Ion Concentration; Leucine; Metabolism; Ornithine; Peptides; Pharmacology; Phenylalanine; Proline; Proteins; Puromycin; Pyruvate Kinase; Pyruvates; Research; Tyrothricin; Valine | 1965 |
THE EFFECT OF ACTINOMYCIN D ON THE PRODUCTION OF GRAMICIDIN S IN WHOLE CELLS OF BACILLUS BREVIS.
Topics: Amino Acids; Bacillus; Dactinomycin; DNA; DNA, Bacterial; Gramicidin; Metabolism; Ornithine; Pharmacology; Phenylalanine; Proline; Proteins; Research; RNA; RNA, Bacterial; Tyrothricin; Uracil | 1965 |
Effects of phenylalanine substitutions in gramicidin A on the kinetics of channel formation in vesicles and channel structure in SDS micelles.
Topics: Amino Acid Motifs; Anti-Bacterial Agents; Dimerization; Electrophysiology; Entropy; Gramicidin; Hot Temperature; Ions; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Phenylalanine; Phosphatidylcholines; Phosphatidylglycerols; Protein Conformation; Protein Structure, Secondary; Sodium Dodecyl Sulfate; Thermodynamics | 2005 |
Proline residue-modified polycationic analogs of gramicidin S with high antibacterial activity against both Gram-positive and Gram-negative bacteria and low hemolytic activity.
Topics: Amination; Anti-Bacterial Agents; Cations; Circular Dichroism; Erythrocytes; Escherichia coli; Gramicidin; Hemolysis; Humans; Molecular Structure; Phenylalanine; Proline; Staphylococcus aureus | 2005 |
Potential analytical applications of gated artificial ion channels.
Topics: Azo Compounds; Biosensing Techniques; Calixarenes; Dimerization; Gramicidin; Ion Channel Gating; Ion Channels; Lipid Bilayers; Models, Biological; Phenylalanine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2005 |
Beta-turn modified gramicidin S analogues containing arylated sugar amino acids display antimicrobial and hemolytic activity comparable to the natural product.
Topics: Acrylates; Amino Acid Sequence; Amino Acids; Amino Sugars; Anti-Bacterial Agents; Bacteria; Biological Products; Erythrocytes; Gramicidin; Hemolysis; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Molecular Sequence Data; Phenylalanine; Proline; Protein Structure, Secondary | 2006 |
Therapeutic index of gramicidin S is strongly modulated by D-phenylalanine analogues at the beta-turn.
Topics: Acinetobacter baumannii; Amino Acid Substitution; Animals; Erythrocytes; Gramicidin; Hemolysis; Hemolytic Agents; Listeria monocytogenes; Microbial Sensitivity Tests; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Structure, Secondary; Sheep; Staphylococcus aureus; Structure-Activity Relationship; Tetrahydroisoquinolines | 2009 |
Synthesis and biological evaluation of asymmetric gramicidin S analogues containing modified D-phenylalanine residues.
Topics: Anti-Bacterial Agents; Erythrocytes; Gramicidin; Hemolysis; Humans; Microbial Sensitivity Tests; Phenylalanine | 2009 |
Sequence inversion and phenylalanine surrogates at the beta-turn enhance the antibiotic activity of gramicidin S.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Gramicidin; Hemolysis; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Phenylalanine; Protein Structure, Secondary; Sheep; Structure-Activity Relationship | 2010 |
Evaluation of readily accessible azoles as mimics of the aromatic ring of D-phenylalanine in the turn region of gramicidin S.
Topics: Anti-Bacterial Agents; Crystallography, X-Ray; Erythrocytes; Gram-Negative Bacteria; Gram-Positive Bacteria; Gramicidin; Humans; Microbial Sensitivity Tests; Molecular Conformation; Phenylalanine; Triazoles | 2011 |
The membrane interface dictates different anchor roles for "inner pair" and "outer pair" tryptophan indole rings in gramicidin A channels.
Topics: Chromatography, Gel; Circular Dichroism; Gramicidin; Indoles; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Tryptophan | 2011 |