phenylalanine and eluxadoline

phenylalanine has been researched along with eluxadoline in 69 studies

Research

Studies (69)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	57 (82.61)	24.3611
2020's	12 (17.39)	2.80

Authors

Authors	Studies
Almenoff, JS; Andrae, D; Covington, PS; Davenport, JM; Dove, LS; Fogel, R; Lembo, A; McIntyre, G; Randall, CW	1
Andrae, DA; Covington, PS; Patrick, DL	1
Devi, LA; Dove, LS; Fujita, W; Gomes, I; McIntyre, G; Prohaska, D	1
Bonifacio, L; Covington, P; Davenport, JM; McIntyre, G; Venitz, J	1
Traynor, K	1
Garnock-Jones, KP	1
Lembo, AJ; Nee, J; Zakari, M	1
Cash, BD; Earnest, DL; Lacy, BE; Rao, T	1
Lacy, BE	1
Andrae, DA; Covington, PS; Davenport, JM; Dove, LS; Lacy, BE; Lembo, AJ; Lopez, R; McIntyre, G; Schey, R; Turner, L; Zuckerman, MJ	1
Rivkin, A; Rybalov, S	1
Storr, M	1
Frieling, T	1
Morgan, B	1
Abenavoli, L; Gasbarrini, A; Ianiro, G; Laterza, L; Scarpellini, E; Tack, J	1
Lacy, BE; Moreau, JC	1
Talley, NJ	1
Bonifacio, L; Covington, PS; Davenport, JM; Dove, LS; Levy-Cooperman, N; McDonnell, M; McIntyre, G; Sellers, EM	1
Weber, HC	1
Cash, BD; Covington, PS; Dove, LS; Lacy, BE; Schoenfeld, PS	4
Cash, BD; Covington, PS; Dove, LS; Fant, RV; Henningfield, JE	1
Boeckxstaens, G; Camilleri, M	1
Corsetti, M; Whorwell, P	1
Andrae, DA; Chey, WD; Covington, PS; Dove, LS	1
Cash, BD; Chey, WD; Covington, PS; Dove, LS; Lacy, BE; Lembo, AJ	1
Keating, GM	1
Berg, JK; Covington, PS; Dove, LS; Marbury, TC	1
Júdez, FJ; Vera, I	1
Bielefeldt, K; Gawron, AJ	1
Barkin, JS; Croteau, R	1
Özdener, AE; Rivkin, A	1
Camilleri, M; Chedid, V; Vijayvargiya, P	1
Brinker, A; Harinstein, L; Wu, E	2
Barbara, G; Barbaro, MR; De Ponti, F; Dothel, G; Raschi, E	1
Coté, GA	1
Bonifacio, L; Covington, PS; Dove, LS; Hunt, TL; McIntyre, G	1
Guo, ZR	1
Chhaparia, A; Hammami, MB; Schroeder, K; Vareedayah, A	1
Akbarali, HI; Dewey, WL; Komla, E; Obeng, S; Selley, DE; Stevens, DL; Wang, H; Zhang, Y; Zheng, Y	1
Corsetti, M; Pannemans, J	1
Abel, JL; Andrae, DA; Carson, RT	1
Chey, WD; Chuang, E; Earnest, DL; Olden, KW; Paul Nicandro, J; Shringarpure, R	1
Dodda, S; Kandhagatla, RN; Makula, A; Polagani, SR	1
Faghih, M; Garcia-Gonzalez, F; Singh, V	1
Gunn, D; Major, GAD	1
Lai, SW	1
Brenner, DM; Cash, BD; Elmes, SJR; Gutman, CR; Jo, E; Liu, LWC; Sayuk, GS	2
Groff, A; Jain, R; Packard, E; Shahid, Z	1
Friedenberg, FK; Piech, G; Reichenbach, ZW; Selby, A	1
Brenner, DM; Sayuk, GS	1
Black, CJ; Ford, AC; Houghton, LA	1
Andrae, DA; Covington, PS; Dove, LS; Lembo, AJ	1
Liu, R; Staller, K	1
Alcaro, S; Corsetti, M; Keszthelyi, D; Lupia, A; Maruca, A; Rocca, R	1
Heidelbaugh, J; Jones, J; Kuritzky, L; Lacy, B; Lembo, A	1
Abel, JL; Brenner, DM; Burslem, K; Sayuk, GS	1
B, S; B, VR; K, MN; Sharma, H; Yerra, S	1
Shah, ED	1
Boinpally, R; Breen-Lyles, M; Busciglio, I; Camilleri, M; Carrothers, TJ; Maselli, D; Muslin, A; Nord, SL; Vijayvargiya, P	1
Boinpally, R; Kaczynski, E; McGeeney, D; Weissman, D	1

Reviews

21 review(s) available for phenylalanine and eluxadoline

Article	Year
Eluxadoline: First Global Approval. Drugs, 2015, Volume: 75, Issue:11 Topics: Adult; Animals; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu	2015
Current and emerging drug options in the treatment of diarrhea predominant irritable bowel syndrome. Expert opinion on pharmacotherapy, 2015, Volume: 16, Issue:18 Topics: Antidepressive Agents, Tricyclic; Antidiarrheals; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine; Receptors, Opioid; Rifamycins; Rifaximin	2015
Rifaximin and eluxadoline - newly approved treatments for diarrhea-predominant irritable bowel syndrome: what is their role in clinical practice alongside alosetron? Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:3 Topics: Abdominal Pain; Anti-Bacterial Agents; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Narcotic Antagonists; Phenylalanine; Receptors, Opioid; Rifamycins; Rifaximin; Serotonin 5-HT3 Receptor Antagonists	2016
Emerging treatments in neurogastroenterology: eluxadoline - a new therapeutic option for diarrhea-predominant IBS. Neurogastroenterology and motility, 2016, Volume: 28, Issue:1 Topics: Antidiarrheals; Carbolines; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Pancreatitis; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2016
Update on the Management of Diarrhea-Predominant Irritable Bowel Syndrome: Focus on Rifaximin and Eluxadoline. Pharmacotherapy, 2016, Volume: 36, Issue:3 Topics: Administration, Oral; Diarrhea; Disease Management; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Randomized Controlled Trials as Topic; Rifamycins; Rifaximin	2016
[Therapy for irritable bowel syndrome in sight?]. Deutsche medizinische Wochenschrift (1946), 2016, Volume: 141, Issue:8 Topics: Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Phenylalanine	2016
Eluxadoline for the treatment of diarrhoea-predominant irritable bowel syndrome. Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:10 Topics: Abdominal Pain; Constipation; Diarrhea; Gastrointestinal Agents; Gastrointestinal Motility; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid	2016
Diarrhea-predominant irritable bowel syndrome: Diagnosis, etiology, and new treatment considerations. Journal of the American Association of Nurse Practitioners, 2016, Volume: 28, Issue:7 Topics: Carbolines; Diarrhea; Disease Management; Humans; Imidazoles; Irritable Bowel Syndrome; Parasympatholytics; Phenylalanine; Rifamycins; Rifaximin; United States	2016
New treatment options for irritable bowel syndrome with predominant diarrhea. Current opinion in endocrinology, diabetes, and obesity, 2017, Volume: 24, Issue:1 Topics: Anti-Bacterial Agents; Constipation; Diarrhea; Drug Therapy, Combination; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Narcotic Antagonists; Phenylalanine; Quality of Life; Receptors, Opioid; Rifamycins; Rifaximin	2017
Dietary and pharmacological treatment of abdominal pain in IBS. Gut, 2017, Volume: 66, Issue:5 Topics: Abdominal Pain; Anti-Infective Agents; Antidepressive Agents; Butyrophenones; Dipeptides; GABA Agents; Gastrointestinal Agents; Histamine H1 Antagonists; Humans; Imidazoles; Irritable Bowel Syndrome; Mentha piperita; Parasympatholytics; Phenylalanine; Piperidines; Plant Oils; Probiotics; Quaternary Ammonium Compounds; Rifamycins; Rifaximin; Serotonin 5-HT3 Receptor Antagonists; Thiophenes; Visceral Pain	2017
New therapeutic options for IBS: the role of the first in class mixed µ- opioid receptor agonist and δ-opioid receptor antagonist (mudelta) eluxadoline. Expert review of gastroenterology & hepatology, 2017, Volume: 11, Issue:4 Topics: Animals; Gastrointestinal Agents; Humans; Imidazoles; Intestinal Mucosa; Intestines; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction; Treatment Outcome	2017
Eluxadoline: A Review in Diarrhoea-Predominant Irritable Bowel Syndrome. Drugs, 2017, Volume: 77, Issue:9 Topics: Adult; Constipation; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Quality of Life; Randomized Controlled Trials as Topic; Receptors, Opioid, delta	2017
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome. The SEPD perspective. Revista espanola de enfermedades digestivas, 2017, Volume: 109, Issue:11 Topics: Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life; Randomized Controlled Trials as Topic	2017
Eluxadoline in the treatment of diarrhea-predominant irritable bowel syndrome. Drug design, development and therapy, 2017, Volume: 11 Topics: Clinical Trials as Topic; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2017
Advancements in drug development for diarrhea-predominant irritable bowel syndrome. Expert opinion on investigational drugs, 2018, Volume: 27, Issue:3 Topics: Animals; Benzimidazoles; Diarrhea; Drug and Narcotic Control; Drug Design; Gastrointestinal Agents; Humans; Imidazoles; Internationality; Irritable Bowel Syndrome; Phenylalanine	2018
[Drug innovation and reverse thinking]. Yao xue xue bao = Acta pharmaceutica Sinica, 2016, Volume: 51, Issue:3 Topics: Drug Discovery; HSP90 Heat-Shock Proteins; Imidazoles; Phenylalanine	2016
Opioid receptors in the GI tract: targets for treatment of both diarrhea and constipation in functional bowel disorders? Current opinion in pharmacology, 2018, Volume: 43 Topics: Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Defecation; Diarrhea; Gastrointestinal Motility; Gastrointestinal Tract; Humans; Imidazoles; Inflammatory Bowel Diseases; Laxatives; Morphinans; Naltrexone; Narcotic Antagonists; Phenylalanine; Polyethylene Glycols; Quaternary Ammonium Compounds; Receptors, Opioid, mu; Signal Transduction	2018
Chronic diarrhoea in adults: what not to miss. Current opinion in gastroenterology, 2019, Volume: 35, Issue:3 Topics: Adenocarcinoma; Adenoma; Antidiarrheals; Bile Acids and Salts; Celiac Disease; Chronic Disease; Colorectal Neoplasms; Diarrhea; Exocrine Pancreatic Insufficiency; Feces; Gastrointestinal Agents; Humans; Iatrogenic Disease; Imidazoles; Immunochemistry; Inflammatory Bowel Diseases; Irritable Bowel Syndrome; Leukocyte L1 Antigen Complex; Loperamide; Malabsorption Syndromes; Phenylalanine; Steatorrhea	2019
Pathophysiology, Differential Diagnosis, and Treatment of Diabetic Diarrhea. Digestive diseases and sciences, 2019, Volume: 64, Issue:12 Topics: Antidiarrheals; Autonomic Nervous System Diseases; Blind Loop Syndrome; Celiac Disease; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diagnosis, Differential; Diarrhea; Diphenoxylate; Enteric Nervous System; Exocrine Pancreatic Insufficiency; Gastrointestinal Agents; Gastrointestinal Motility; Hypoglycemic Agents; Imidazoles; Inflammation; Inflammatory Bowel Diseases; Interstitial Cells of Cajal; Intestinal Absorption; Intestinal Mucosa; Irritable Bowel Syndrome; Loperamide; Neuroglia; Non-Nutritive Sweeteners; Oxidative Stress; Phenylalanine; Serotonin 5-HT3 Receptor Antagonists	2019
Current US Food and Drug Administration-Approved Pharmacologic Therapies for the Treatment of Irritable Bowel Syndrome with Diarrhea. Advances in therapy, 2020, Volume: 37, Issue:1 Topics: Adult; Carbolines; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life; Rifaximin; United States; United States Food and Drug Administration	2020
Update on Eluxadoline for the Treatment of Irritable Bowel Syndrome with Diarrhea: Patient Selection and Perspectives. Drug design, development and therapy, 2020, Volume: 14 Topics: Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Patient Selection; Phenylalanine	2020

Trials

11 trial(s) available for phenylalanine and eluxadoline

Article	Year
Eluxadoline benefits patients with irritable bowel syndrome with diarrhea in a phase 2 study. Gastroenterology, 2013, Volume: 145, Issue:2 Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, mu; Treatment Outcome	2013
Effect of uptake transporters OAT3 and OATP1B1 and efflux transporter MRP2 on the pharmacokinetics of eluxadoline. Journal of clinical pharmacology, 2015, Volume: 55, Issue:5 Topics: Adult; Area Under Curve; Cross-Over Studies; Cyclosporine; Half-Life; Humans; Imidazoles; Liver-Specific Organic Anion Transporter 1; Metabolic Clearance Rate; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Phenylalanine; Probenecid	2015
Eluxadoline for Irritable Bowel Syndrome with Diarrhea. The New England journal of medicine, 2016, Jan-21, Volume: 374, Issue:3 Topics: Abdominal Pain; Adult; Aged; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Pancreatitis; Phenylalanine	2016
[A new remedy for diarrheal irritable bowel syndrome]. MMW Fortschritte der Medizin, 2016, Mar-17, Volume: 158, Issue:5 Topics: Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; United States	2016
Abuse Potential and Pharmacodynamic Characteristics of Oral and Intranasal Eluxadoline, a Mixed μ- and κ-Opioid Receptor Agonist and δ-Opioid Receptor Antagonist. The Journal of pharmacology and experimental therapeutics, 2016, Volume: 359, Issue:3 Topics: Administration, Intranasal; Administration, Oral; Adult; Dose-Response Relationship, Drug; Female; Humans; Imidazoles; Male; Phenylalanine; Psychometrics; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance-Related Disorders	2016
Safety of Eluxadoline in Patients with Irritable Bowel Syndrome with Diarrhea. The American journal of gastroenterology, 2017, Volume: 112, Issue:2 Topics: Abdominal Pain; Adult; Aged; Constipation; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Nausea; Pancreatitis; Phenylalanine; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Spasm; Sphincter of Oddi Dysfunction	2017
Early response predicts a sustained response to eluxadoline in patients with irritable bowel syndrome with diarrhoea in two Phase 3 studies. Alimentary pharmacology & therapeutics, 2017, Volume: 45, Issue:10 Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Prognosis; Retrospective Studies; Time Factors	2017
Eluxadoline Efficacy in IBS-D Patients Who Report Prior Loperamide Use. The American journal of gastroenterology, 2017, Volume: 112, Issue:6 Topics: Abdominal Pain; Adult; Antidiarrheals; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Pain Measurement; Phenylalanine; Symptom Assessment	2017
Evaluation of Eluxadoline Effect on Cardiac Repolarization. Clinical pharmacology in drug development, 2018, Volume: 7, Issue:7 Topics: Administration, Oral; Adult; Cross-Over Studies; Electrocardiography; Female; Gastrointestinal Agents; Healthy Volunteers; Heart; Heart Function Tests; Humans; Imidazoles; Male; Middle Aged; Moxifloxacin; Phenylalanine; Young Adult	2018
Efficacy and Safety of Eluxadoline in Patients With Irritable Bowel Syndrome With Diarrhea Who Report Inadequate Symptom Control With Loperamide: RELIEF Phase 4 Study. The American journal of gastroenterology, 2019, Volume: 114, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Phenylalanine; Prospective Studies	2019
Effects of treatment with eluxadoline on abdominal pain in patients with IBS-D: Additional post hoc analyses of Phase 3 trials. Neurogastroenterology and motility, 2020, Volume: 32, Issue:4 Topics: Abdominal Pain; Adult; Aged; Diarrhea; Double-Blind Method; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Treatment Outcome	2020

Other Studies

37 other study(ies) available for phenylalanine and eluxadoline

Article	Year
Item-level assessment of the irritable bowel syndrome quality of life questionnaire in patients with diarrheal irritable bowel syndrome. Clinical therapeutics, 2014, Volume: 36, Issue:5 Topics: Clinical Trials, Phase II as Topic; Diarrhea; Female; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Models, Psychological; Phenylalanine; Psychometrics; Quality of Life; Surveys and Questionnaires	2014
Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers. Biochemical pharmacology, 2014, Dec-01, Volume: 92, Issue:3 Topics: Animals; Arrestins; beta-Arrestins; Castor Oil; Diarrhea; Humans; Imidazoles; Ligands; Loperamide; Male; Mice, Inbred C57BL; Mice, Mutant Strains; Phenylalanine; Protein Multimerization; Receptors, Opioid, delta; Receptors, Opioid, mu; Signal Transduction	2014
Eluxadoline approved for irritable bowel syndrome with diarrhea. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2015, Jul-01, Volume: 72, Issue:13 Topics: Constipation; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; United States; United States Food and Drug Administration	2015
Eluxadoline (Viberzi) for irritable bowel syndrome with diarrhea. The Medical letter on drugs and therapeutics, 2016, Jan-04, Volume: 58, Issue:1485 Topics: Administration, Oral; Adult; Diarrhea; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Receptors, Opioid, mu; United States; United States Food and Drug Administration	2016
The latest drug therapies for treating IBS. Longtime sufferers of irritable bowel syndrome have new options for relief. Health after 50 with Scientific American Consumer Health, 2015, Volume: 27, Issue:12 Topics: Chronic Disease; Drug Approval; Gastrointestinal Agents; Humans; Imidazoles; Peptides; Phenylalanine; Rifamycins; Rifaximin; United States; United States Food and Drug Administration	2015
Drug development: A healthy pipeline. Nature, 2016, 05-19, Volume: 533, Issue:7603 Topics: Animals; Benzimidazoles; Benzofurans; Bile Acids and Salts; Carbolines; Colesevelam Hydrochloride; Colestipol; Disease Models, Animal; Enteric Nervous System; Female; Humans; Imidazoles; Indoles; Irritable Bowel Syndrome; Loperamide; Lubiprostone; Male; Mice; Natriuretic Peptides; Peptides; Phenylalanine; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Rifamycins; Rifaximin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Visceral Pain	2016
Board Review Vignette: Irritable Bowel Syndrome. The American journal of gastroenterology, 2016, Volume: 111, Issue:9 Topics: Abdominal Pain; Adult; Anion Exchange Resins; Antidiarrheals; Carbolines; Cholestyramine Resin; Constipation; Diarrhea; Disease Management; Female; Gastrointestinal Agents; Guanylyl Cyclase C Agonists; Humans; Imidazoles; Irritable Bowel Syndrome; Laxatives; Loperamide; Peptides; Phenylalanine; Probiotics; Rifamycins; Rifaximin; Selective Serotonin Reuptake Inhibitors	2016
Eluxadoline Demonstrates a Lack of Abuse Potential in Phase 2 and 3 Studies of Patients With Irritable Bowel Syndrome With Diarrhea. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017, Volume: 15, Issue:7 Topics: Administration, Oral; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Double-Blind Method; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Placebos; Randomized Controlled Trials as Topic; Single-Blind Method; Substance-Related Disorders	2017
In brief: Pancreatitis with eluxadoline (Viberzi) in patients without a gallbladder. The Medical letter on drugs and therapeutics, 2017, 04-24, Volume: 59, Issue:1519 Topics: Cholecystectomy; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Pancreatitis; Phenylalanine; Risk Factors	2017
Effect of Hepatic Impairment on Eluxadoline Pharmacokinetics. Journal of clinical pharmacology, 2017, Volume: 57, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Female; Gastrointestinal Agents; Humans; Imidazoles; Liver Diseases; Male; Middle Aged; Phenylalanine; Treatment Outcome; Young Adult	2017
Risk of Pancreatitis Following Treatment of Irritable Bowel Syndrome With Eluxadoline. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2018, Volume: 16, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Agents; Humans; Imidazoles; Incidence; Irritable Bowel Syndrome; Male; Middle Aged; Pancreatitis; Phenylalanine; Product Surveillance, Postmarketing; Risk Assessment	2018
Τ Eluxadoline for IBS-D. Drug and therapeutics bulletin, 2017, Volume: 55, Issue:8 Topics: Contraindications, Drug; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2017
Safety of Eluxadoline in Patients With IBS-D Without a Gallbladder. The American journal of gastroenterology, 2017, Volume: 112, Issue:10 Topics: Cholecystectomy; Gallbladder; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Treatment Outcome	2017
Response to Croteau and Barkin. The American journal of gastroenterology, 2017, Volume: 112, Issue:10 Topics: Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2017
Safety of Eluxadoline in Patients With Irritable Bowel Syndrome. The American journal of gastroenterology, 2017, Volume: 112, Issue:10 Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2017
Advantages and Limitations of the Federal Adverse Events Reporting System in Assessing Adverse Event Reporting for Eluxadoline. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2018, Volume: 16, Issue:3 Topics: Humans; Imidazoles; Irritable Bowel Syndrome; Pancreatitis; Phenylalanine	2018
Postmarketing cases of eluxadoline-associated pancreatitis in patients with or without a gallbladder. Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:6 Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Databases, Factual; Female; Gallbladder; Gallbladder Diseases; Humans; Imidazoles; Male; Middle Aged; Pancreatitis; Phenylalanine; Product Surveillance, Postmarketing; Retrospective Studies; United States; United States Food and Drug Administration; Young Adult	2018
Editorial: the sphincter of Oddi strikes again-eluxadoline illuminates a controversial mechanism for the pathogenesis of acute pancreatitis. Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:9 Topics: Acute Disease; Gallbladder; Humans; Imidazoles; Pancreatitis; Phenylalanine; Sphincter of Oddi	2018
Eluxadoline-Associated Pancreatitis in a Post-Cholecystectomy Patient: A Case Report. Delaware medical journal, 2017, Volume: 89, Issue:3 Topics: Adult; Cholecystectomy; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Pancreatitis; Phenylalanine	2017
Methylation Products of 6β- N-Heterocyclic Substituted Naltrexamine Derivatives as Potential Peripheral Opioid Receptor Modulators. ACS chemical neuroscience, 2018, 12-19, Volume: 9, Issue:12 Topics: Analgesics, Opioid; Animals; CHO Cells; Constipation; Cricetulus; Diarrhea; Drug Partial Agonism; Gastrointestinal Agents; Gastrointestinal Transit; Imidazoles; Methylation; Mice; Molecular Docking Simulation; Morphine; Naltrexone; Narcotic Antagonists; Nociception; Phenylalanine; Quaternary Ammonium Compounds; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu	2018
The impact of treatment with eluxadoline on health-related quality of life among adult patients with irritable bowel syndrome with diarrhea. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019, Volume: 28, Issue:2 Topics: Adult; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Male; Middle Aged; Phenylalanine; Quality of Life; Surveys and Questionnaires	2019
Alosetron versus traditional pharmacotherapy in clinical practice: effects on resource use, health-related quality of life, safety and symptom improvement in women with severe diarrhea-predominant irritable bowel syndrome. Current medical research and opinion, 2019, Volume: 35, Issue:3 Topics: Adult; Aged; Carbolines; Diarrhea; Female; Health Resources; Humans; Imidazoles; Irritable Bowel Syndrome; Middle Aged; Phenylalanine; Quality of Life; Rifaximin	2019
High sensitive LC-MS/MS method for estimation of eluxadoline in human plasma and its application to pharmacokinetic study. Journal of pharmaceutical and biomedical analysis, 2019, Feb-20, Volume: 165 Topics: Chromatography, Liquid; Gastrointestinal Agents; Glucuronides; Humans; Imidazoles; India; Male; Phenylalanine; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry	2019
Letter: eluxadoline-associated acute pancreatitis-myth or reality? Authors' reply. Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:4 Topics: Gallbladder; Humans; Imidazoles; Pancreatitis; Phenylalanine	2018
Letter: eluxadoline-associated acute pancreatitis-myth or reality? Alimentary pharmacology & therapeutics, 2018, Volume: 48, Issue:4 Topics: Gallbladder; Humans; Imidazoles; Pancreatitis; Phenylalanine	2018
Safety of Eluxadoline Use. The American journal of gastroenterology, 2019, Volume: 114, Issue:7 Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2019
Response to Lai. The American journal of gastroenterology, 2019, Volume: 114, Issue:7 Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2019
Eluxadoline-induced pancreatitis occurring in an adult man without a prior cholecystectomy. BMJ case reports, 2019, Aug-28, Volume: 12, Issue:8 Topics: Abdominal Pain; Humans; Imidazoles; Male; Middle Aged; Pancreatitis; Phenylalanine	2019
Efficacy of Eluxadoline in Irritable Bowel Syndrome With Diarrhea. The American journal of gastroenterology, 2020, Volume: 115, Issue:3 Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine	2020
Response to Black et al. The American journal of gastroenterology, 2020, Volume: 115, Issue:3 Topics: Diarrhea; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Phenylalanine	2020
In Silico Food-Drug Interaction: A Case Study of Eluxadoline and Fatty Meal. International journal of molecular sciences, 2020, Nov-30, Volume: 21, Issue:23 Topics: Diet, High-Fat; Dietary Fats; Fats; Food-Drug Interactions; Humans; Imidazoles; Meals; Models, Molecular; Molecular Conformation; Monte Carlo Method; Phenylalanine; Static Electricity; Structure-Activity Relationship	2020
Management of irritable bowel syndrome with diarrhea: focus on eluxadoline. Current medical research and opinion, 2021, Volume: 37, Issue:4 Topics: Adult; Aged; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2021
Improved work productivity and health-related quality of life in patients with irritable bowel syndrome with diarrhea receiving eluxadoline following inadequate response to loperamide. Journal of managed care & specialty pharmacy, 2021, Volume: 27, Issue:4 Topics: Absenteeism; Adolescent; Adult; Aged; Aged, 80 and over; Diarrhea; Female; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Loperamide; Male; Middle Aged; Phenylalanine; Quality of Life; Surveys and Questionnaires; United States; Young Adult	2021
A novel stability-indicating HPLC method for the determination of enantiomeric purity of eluxadoline drug: Amylose tris(3,5-dichlorophenyl carbamate) stationary phase. Biomedical chromatography : BMC, 2022, Volume: 36, Issue:2 Topics: Amylose; Chromatography, High Pressure Liquid; Drug Stability; Imidazoles; Linear Models; Phenylalanine; Phenylcarbamates; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism	2022
Delta Variant: Expanding the Indication for Eluxadoline to Bile Acid Diarrhea. Digestive diseases and sciences, 2022, Volume: 67, Issue:8 Topics: Bile Acids and Salts; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine	2022
Safety and Efficacy of Eluxadoline in Patients with Irritable Bowel Syndrome-Diarrhea With or Without Bile Acid Diarrhea: Open-Label Study. Digestive diseases and sciences, 2022, Volume: 67, Issue:8 Topics: Adult; Bile Acids and Salts; Diarrhea; Gastrointestinal Agents; Humans; Imidazoles; Irritable Bowel Syndrome; Phenylalanine; Quality of Life	2022
An Open-Label Study to Evaluate the Effect of Eluxadoline on the Single-Dose Pharmacokinetics of Midazolam in Healthy Participants. Clinical pharmacology in drug development, 2022, Volume: 11, Issue:11 Topics: Adult; Cytochrome P-450 CYP3A; Healthy Volunteers; Humans; Midazolam; Phenylalanine	2022