phenylalanine has been researched along with deuterium in 213 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 87 (40.85) | 18.7374 |
| 1990's | 46 (21.60) | 18.2507 |
| 2000's | 57 (26.76) | 29.6817 |
| 2010's | 20 (9.39) | 24.3611 |
| 2020's | 3 (1.41) | 2.80 |
| Authors | Studies |
|---|---|
| Bartl, K; Cavalar, C; Günther, H; Hull, WE; Krebs, T; Rétey, J; Ripp, E; Simon, H | 1 |
| Bright, HJ; Porter, DJ; Voet, JG | 1 |
| Kaufman, S; Milstien, S | 1 |
| Kearns, DR; Rordorf, BF | 1 |
| Matthews, HR; Matthews, KS; Opella, SJ | 1 |
| Beguin, CG; Chesne, S; Gout, E; Pelmont, J | 1 |
| Johnston, PD; Redfield, AG | 1 |
| Dobson, CM; Woodworth, RC | 1 |
| Bartholomé, K; Erlenmaier, T; Hunneman, DH; Lutz, P; Trefz, FK | 1 |
| Kokolis, N; Stichler, W; Ziegler, I | 1 |
| Fell, V; Hoskins, JA; Pollitt, RJ | 1 |
| Bartholomé, K; Bickel, H; Lutz, P; Schmidt, H; Trefz, FK | 1 |
| Hruby, VJ; Linn, DK; Upson, DA; Yamamoto, DM | 1 |
| Hoskins, JA | 1 |
| Kallen, RG; Ulevitch, RJ | 1 |
| Burgen, AS; Feeney, J; Griffiths, DV; Roberts, GC | 1 |
| Blaskovics, ME; Byrd, DJ; Kochen, W; Lutz, P; Trefz, FK | 1 |
| Ajisaka, K; Kainosho, M; Kamisaku, M; Kyogoku, Y; Murai, A | 1 |
| MacLachlan, LK; Reid, DG; Sweeney, PJ; Walker, JM; Waltho, JP | 1 |
| Evans, PD; Macfarlane, RG; Midgley, JM; Watson, DG | 1 |
| Halliday, D; Leonard, JV; Thompson, GN; Walter, JH | 1 |
| Chapman, SK; Dubois, J; Lederer, F; Mathews, FS; Reid, GA | 1 |
| Hoerr, RA; Krempf, M; Marks, L; Young, VR | 1 |
| Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K | 1 |
| Clemens, P; Fischer, R; Grüttner, R; Heinrich, HC; Lehmann, WD | 1 |
| Kiick, DM; Phillips, RS | 1 |
| Benkovic, SJ; Chen, JT; Taira, K; Tu, CP | 1 |
| Heinrich, HC; Lehmann, WD | 2 |
| Cleland, WW; Hermes, JD; Weiss, PM | 1 |
| Morita, F; Shimizu, T; Yagi, K | 1 |
| Udenfriend, S | 1 |
| Graham, JM; Wallach, DF | 1 |
| Attridge, TH; Johnson, CB; Smith, H | 1 |
| Attridge, TH; Smith, H | 1 |
| Grathwohl, C; Wüthrich, K | 1 |
| Bertani, A; Bollini, R; Lanzani, GA; Soffientini, AN | 1 |
| Faulstich, H; Trischmann, H | 1 |
| Markley, JL | 1 |
| Kaplan, S; Kosakowski, MH | 1 |
| Hunkapiller, MW; Richards, JH | 1 |
| Hartman, KA; Medeiros, GC; Thomas, GJ | 1 |
| Narayanan, TK; Rao, GR | 1 |
| Ladner, JE; Schweizer, MP | 1 |
| Bierbaum, J; Chládek, S; Ofengand, J; Robilard, G | 1 |
| Baerlocher, K; Curtius, HC; Völlmin, JA | 2 |
| Battersby, AR; Hanson, KR; Staunton, J; Wightman, RH | 1 |
| Blake, MI; Kluza, RB; Rhodes, HJ | 1 |
| Daly, JW; Jerina, DM; Reed, DJ; Vimmerstedt, J | 1 |
| Patel, DJ | 1 |
| Kirby, GW; Michael, J | 1 |
| Hill, RK; Kumagai, H; Mugibayashi, Y; Ogata, K; Sawada, S; Yamada, H | 1 |
| Jones, JB; Lewis, AJ; Sneddon, DW | 1 |
| Nakada, D | 1 |
| Böck, A; Kosakowski, MH; Neidhardt, FC | 1 |
| Silver, MS; Stein, TP; Stoddard, M | 1 |
| Lewin, S; Potter, BJ; Williams, BA | 1 |
| Feder, J; Schuck, JM | 1 |
| Herskovits, TT; Sorensen, ME | 1 |
| Chan, SI; Crawford, JE; Schweizer, MP | 1 |
| Faulstich, H; Goodman, M; Naider, F; Patel, DJ; Tonelli, AE; Wieland, T | 1 |
| Adams, MH; Midthun, RA; Rowley, PT | 1 |
| Blomquist, AT; Cedergren, RJ; Harpp, DN; Hiscock, BF; Tripp, SL | 1 |
| Kaiser, BL; Kaiser, ET | 1 |
| Herskovits, TT; Menendez, CJ | 1 |
| Crespi, HL; Daboll, HF; Katz, JJ | 1 |
| Siemion, IZ; Sucharda-Sobczyk, A | 1 |
| Föry, W; MacKenzie, RE; McCormick, DB; Wu, FY | 1 |
| Abdullaev, ND; Bystrov, VF; Efremov, ES; Ivanov, VT; Miroshnikov, AI; Ovchinnikov, YA; Senyavina, LB; Shepel, EN | 1 |
| Binns, F; King, JA; Percival, A; Robson, NC; Swan, GA | 1 |
| Beardsley, K; Cantor, CR; Tao, T | 1 |
| Bennett, DJ; Kirby, GW; Moss, VA | 1 |
| Lord, RC; Yu, NT | 1 |
| Cohen, JS | 1 |
| Scheraga, HA; Silverman, DN | 1 |
| Ludescher, U; Schwyzer, R | 1 |
| Murakami, TH; Zimmerman, AM; Zimmerman, SB | 1 |
| Cannella, C; Scandurra, R | 1 |
| Bright, HJ; Porter, DJ | 1 |
| Cross, DG; Fisher, HF | 1 |
| Calf, GE; Garnett, JL; Halpern, BH; Turnbull, K | 1 |
| Auer, HE; Doty, P | 1 |
| Daly, J; Guroff, G; Reifsnyder, CA | 1 |
| Daly, J; Guroff, G | 1 |
| Clemens, P; Grüttner, R; Heinrich, HC; Lehmann, WD; Theobald, N | 1 |
| Bier, D; Matalon, R; Matthews, DE; Michals, K | 1 |
| Fischer, R; Heinrich, HC; Lehmann, WD; Theobald, N | 1 |
| Garssen, GJ; Hilbers, CW; Schoenmakers, JG; Tesser, GI | 1 |
| Khaled, MA; Lacey, JC; Watkins, CL | 1 |
| Bier, DM; Clarke, JT | 1 |
| Kinsey, RA; Kintanar, A; Oldfield, E | 1 |
| Hammen, HW; Matthiesen, U; Schadewaldt, P; Wendel, U | 1 |
| Fong, Y; He, W; Lowry, SF; Marano, MA; Matthews, DE; Moldawer, LL | 1 |
| Bryant, RG; Zhang, H | 2 |
| Balasubramanian, S; Benkovic, SJ; Carr, RT; Hawkins, PC | 1 |
| Biolo, G; Inchiostro, S; Tessari, P; Tiengo, A | 1 |
| Anderson, SE; Ballmer, PE; Essen, P; Garlick, PJ; McNurlan, MA | 1 |
| Anderson, SE; Ballmer, PE; Calder, AG; Essén, P; Grant, I; Ljungqvist, O; McNurlan, MA; Sandgren, A; Thorell, A; Tjäder, I | 1 |
| Ball, RO; Marai, L; Pencharz, PB; Tung, AS; Zello, GA | 1 |
| Fuller, JC; Huiatt, TW; Nissen, SL | 1 |
| Richards, FM; Sykes, BD; Wishart, DS | 1 |
| Gleason, R; Hoerr, RA; Krempf, M; Marks, LM; Pelletier, VA; Young, VR | 1 |
| Ball, RO; Pencharz, PB; Zello, GA | 1 |
| Basile Filho, A; Beaumier, L; Castillo, L; Chapman, TE; El-Khoury, AE; Sanchez, M; Young, VR | 1 |
| Burrin, DG; Frazer, EM; Henry, J; Jahoor, F; Reeds, PJ; Wykes, L | 1 |
| Anderson, SE; Ballmer, PE; Garlick, PJ; McNurlan, MA; Reichen, J; Sterchi, AB | 1 |
| Honda, C; Kamisako, W; Suwa, K; Takeyama, S; Terada, K | 1 |
| Schaefer, JR; Schweer, H; Seyberth, HW; Steinmetz, A; Watzer, B | 1 |
| Fujii, N; Fujiwara, Y; Kasahara, M; Kiyama, Y; Kuroda, Y; Nakagawa, T; Nasu, H; Ogawa, M; Terashima, M; Wakita, M | 1 |
| Falconer, JS; Fearon, KC; McMillan, DC; Preston, T; Slater, C | 1 |
| Bergmann, S; Gehrisch, S; Hanefeld, M; Jaross, W; Julius, U; Leonhardt, W; Nitzsche, S; Pietzsch, J; Wiedemann, B | 1 |
| Bartlett, K; Brock, C; Craft, AW; Daley, SE; Halliday, D; Hetherington, C; Kernahan, J; Pearson, AD; Price, L; Wyllie, RA | 1 |
| Anderson, SE; Calder, AG; Connell, A; Lobley, GE | 1 |
| Doi, T; Hamada, K; Imaizumi, K; Matsumoto, K; Okamura, K; Sakurai, M; Shimizu, S; Suzuki, M; Yoshioka, Y | 1 |
| Aarsland, A; Phillips, SM; Tipton, KD; Wolf, SE; Wolfe, RR | 1 |
| Abumrad, NN; Dorton, S; Garlick, PJ; Hashiguchi, Y; McNurlan, MA; Molina, PE; Reddy, D | 1 |
| Bozzetti, F; Dworzak, F; Ferrari, P; Gavazzi, C; Maiorana, C | 1 |
| Burrin, DG; Henry, J; Jahoor, F; Reeds, PJ; Stoll, B | 1 |
| Schäfer, R | 1 |
| Ballmer, PE | 1 |
| Raleigh, DP; Wu, WJ | 1 |
| Beaufrère, B; Boirie, Y; Bouteloup-Demange, C; Déchelotte, P; Gachon, P | 1 |
| Basile-Filho, A; Beaumier, L; El-Khoury, AE; Gleason, RE; Kenneway, M; Young, VR; Yu, YM | 1 |
| Bark, TH; Garlick, PJ; Lang, CH; McNurlan, MA | 1 |
| Evans, PR; Leadlay, PF; Meier, TW; Thomä, NH | 1 |
| Gloge, A; Langer, B; Poppe, L; Rétey, J | 1 |
| Ball, RO; Filler, RM; Moore, AM; Pencharz, PB; Roberts, SA | 1 |
| Backwell, FR; Bequette, BJ; Buchan, V; Calder, AG; Crompton, LA; France, J; Kyle, CE; MaCrae, JC | 1 |
| Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M | 1 |
| Doyle, D; Ferrando, AA; Phillips, SM; Tipton, KD; Wolfe, RR | 1 |
| De Biasi, L; Deferrari, G; Garibotto, G; Pastorino, N; Robaudo, C; Tessari, P; Vettore, M | 1 |
| Cline, GW; Mack, GW; Nadel, ER; Nagashima, K; Shulman, GI | 1 |
| Anderson, VE; Chen, YH; Goshe, MB | 1 |
| Chin, JK; Klinman, JP | 1 |
| Manitto, P; Monti, D; Speranza, G | 1 |
| Herndon, DN; Jeschke, MG; Volpi, E; Wolfe, RR | 1 |
| Lee, CH; Taylor, R; Whittaker, PG | 1 |
| Buijs, J; Hagman, C; Håkansson, K; Håkansson, P; Oscarsson, S; Richter, JH | 1 |
| Klinman, JP; Tsai , S | 1 |
| Arabshahi, A; Berger, E; Frey, PA; Schilling, JF; Wei, Y | 1 |
| Barle, H; Essén, P; Gamrin, L; Garlick, PJ; McNurlan, MA; Wernerman, J | 1 |
| Angeletti, RH; Grubmeyer, C; Nieves, E; Schramm, VL; Shi, W; Wang, F | 1 |
| Miller, SL; Owens-Stovall, SK; Petrini, BE; Rasmussen, BB; Tipton, KD; Wolf, SE; Wolfe, RR | 1 |
| Cesar, D; Evans, WJ; Hellerstein, M; Lambert, CP; Trappe, TA; White, F | 1 |
| Devapatla, S; Gruca, L; Hanson, RW; Kalhan, SC; O'Brien, AM; Parimi, PS | 1 |
| Caso, G; Ford, GC; Garlick, PJ; McNurlan, MA; Nair, KS | 1 |
| Cunje, A; Hopkinson, AC; Shoeib, T; Siu, KW | 1 |
| Fitzpatrick, PF; Frantom, PA; Pongdee, R; Sulikowski, GA | 1 |
| Boitano, AE; Jones, JP; Rock, DA; Wahlstrom, JL | 1 |
| Børsheim, E; Tipton, KD; Wolf, SE; Wolfe, RR | 1 |
| Braulio, VB; Deutz, NE; Luiking, YC; Vissers, YL; von Meyenfeldt, MF | 1 |
| Blackburn, NJ; Francisco, WA; Klinman, JP | 1 |
| Claeyssens, S; Coëffier, M; Déchelotte, P; Ducrotté, P; Hecketsweiler, B; Lavoinne, A | 1 |
| Babraj, JA; Berré, J; Boisseau, N; Brassine, E; Cuthbertson, DJ; Francaux, M; Louis, M; Poortmans, JR; Rennie, MJ; Smith, K; Waddell, T | 1 |
| Ito, Y; Laue, ED; Nakayama, H; Nietlispach, D; Rajesh, S; Shibata, T; Takio, K | 1 |
| Brenna, E; Fronza, G; Fuganti, C; Pinciroli, M | 1 |
| Sakakibara, N; Shimada, M; Suzuki, S; Umezawa, T | 1 |
| Aarsland, A; Børsheim, E; Cree, MG; Elliott, TA; Tipton, KD; Wolfe, RR | 1 |
| Kazazić, S; Klasinc, L; Rozman, M; Srzić, D | 1 |
| Fitzpatrick, PF; Sobrado, P | 1 |
| Go, EP; Harris, K; Shen, Z; Siuzdak, G | 1 |
| Albright, R; Bigelow, M; Boirie, Y; Nair, KS | 1 |
| Carroll, CC; Fluckey, JD; Sullivan, DH; Trappe, TA; Williams, RH | 1 |
| Badaloo, A; Forrester, T; Heird, WC; Jahoor, F; Reid, M | 1 |
| Cody, RB; Wolfe, RR; Wu, Z; Zhang, XJ | 1 |
| Demidkina, TV; Faleev, NG; Phillips, RS; Tsvetikova, MA; Yamskov, IA | 1 |
| Balali-Mood, K; Bradshaw, JP; Harroun, TA; Katsaras, J | 1 |
| Cranendonk, A; de Boo, HA; Harding, JE; Kulik, W; Lafeber, HN | 1 |
| Gruca, LL; Kalhan, SC; Parimi, PS | 1 |
| Frieden, C; Li, H | 1 |
| Aarsland, A; Katsanos, CS; Kobayashi, H; Sheffield-Moore, M; Wolfe, RR | 1 |
| Fitzpatrick, PF; Pavon, JA | 2 |
| Fukushima, K; Imai, T; Nomura, M | 1 |
| Ballmer, PE; Bärtsch, P; Casella, GA; Garlick, PJ; Imoberdorf, R; Marini, JC; McNurlan, MA; Turgay, M | 1 |
| Jack, E; Middleton, DA; Newsome, M; Radford, SE; Stockley, PG | 1 |
| Feng, L; Lee, HS; Prestegard, JH | 1 |
| Mamer, OA; Sarkissian, CN; Scriver, CR | 1 |
| Christiansen, JS; Gravholt, CH; Møller, N; Riis, AL | 1 |
| Basu, G; Chakrabarti, P; Dasgupta, B | 1 |
| Arrastia, CD; Casperson, SL; Dillon, EL; Paddon-Jones, D; Sanford, AP; Sheffield-Moore, M; Sinha, S; Urban, RJ; Volpi, E; Wolfe, RR | 1 |
| Strobel, SA; Zhong, M | 1 |
| Barazzoni, R; Cecchet, D; Kiwanuka, E; Orlando, R; Tessari, P; Vettore, M; Zanetti, M | 1 |
| Gupta, A; Matsui, K; Mukherjee, A; Roth, JP | 1 |
| Bregendahl, K; Fan, MZ; Liu, L; Rideout, TC; Shen, Y; Werchola, G; Yang, X; Yen, JT | 1 |
| Lenferink, A; Otto, C; van Manen, HJ | 1 |
| Ahn, H; Caso, G; Gelato, MC; Kelly, P; McNurlan, MA; Mileva, I | 1 |
| Boirie, Y; de Roos, AL; Fauquant, J; Gijsen, AP; Kies, AK; Koopman, R; Lemosquet, S; Saris, WH; van Loon, LJ | 1 |
| Preston, T; Small, AC | 1 |
| Baldini, L; Casnati, A; Kalenius, E; Neitola, R; Sansone, F; Torvinen, M; Ungaro, R; Vainiotalo, P | 1 |
| Dangott, LJ; Fitzpatrick, PF; Li, J | 1 |
| Ellden, J; Hoatson, GL; Khadjinova, A; Ostrovsky, D; Vold, RL; Vugmeyster, L | 1 |
| de Lange, A; Gijsen, AP; Groen, B; Pennings, B; Senden, JM; van Loon, LJ; Zorenc, AH | 1 |
| Avila, C; Cimino, G; Cutignano, A; Domenech-Coll, A; Fontana, A; Laratta, B; Mollo, E; Romano, G; Rosica, A | 1 |
| Holland, GP; Shi, X; Yarger, JL | 1 |
| Dänicke, S; Kersten, S; Valenta, H; Wilkerling, K | 1 |
| Bôle-Feysot, C; Cailleux, AF; Claeyssens, S; Coëffier, M; Déchelotte, P; Donnadieu, N; Guérin, C; Lavoinne, A; Lecleire, S; Maurer, B | 1 |
| Gijsen, AP; Ottenbros, CL; Senden, JM; Snijders, T; van Loon, LJ; Verdijk, LB; Wall, BT | 1 |
| Bahadorani, J; Chinkes, DL; Killewich, LA; Sheffield-Moore, M; Tuvdendorj, D; Wolfe, RR; Zhang, XJ | 1 |
| Blier, PU; Driedzic, WR; Lamarre, SG; Saulnier, RJ | 1 |
| Adams, EM; Allen, HC; Cwiklik, L; Griffith, EC; Perkins, RJ; Roeselová, M; Telesford, DM; Vaida, V | 1 |
| Giblin, D; Gross, ML; Niu, B; Rempel, DL; Zhang, H | 1 |
| Badaloo, A; Baker, TM; Bohren, KM; Dwarkanath, P; Hsu, JW; Jahoor, F; Kao, CC; Karnes, JM; Kurpad, AV; Thame, MM | 1 |
| Burd, NA; Franssen, R; Gijsen, AP; Gorissen, SH; Senden, JM; Snijders, T; van Loon, LJ; Wall, BT | 1 |
| Bali, G; Cangemi, V; Davison, B; Evans, BR; Howard, C; Kinney, B; Lavenhouse, F; O'Neill, H; Partee, C; Ragauskas, A; Ramey, K; Ramirez, D; Shah, R; Ware, T; Weston, K | 1 |
| Adams, LA; Graham, B; Loh, CT; Otting, G | 1 |
| Pedras, MSC; To, QH | 1 |
| Cobelli, C; Klaus, K; Moran, A; Nair, KS; Schiavon, M; Toffolo, G; Vella, A | 1 |
| Balachandran, N; Berti, PJ; Grainger, RA; Junop, MS; Liuni, P; Rob, T; Wilson, DJ | 1 |
| Pająk, M; Pałka, K; Podsadni, K | 1 |
| Afsari, S; Ghirlanda, G; Halloran, N; Lindsay, S; Mukherjee, S; Ryan, E; Wang, X | 1 |
1 review(s) available for phenylalanine and deuterium
| Article | Year |
|---|---|
Arene oxide intermediates in enzymatic hydroxylation and their significance with respect to drug toxicity.
Topics: Acetanilides; Amphetamine; Bromine; Chemical Phenomena; Chemistry; Chlorine; Deuterium; Ethers, Cyclic; Fenclonine; Fluorine; Glutathione; Mixed Function Oxygenases; Naphthalenes; Phenols; Phenylalanine; Phenylpyruvic Acids; Tritium; Tryptophan | 1971 |
15 trial(s) available for phenylalanine and deuterium
| Article | Year |
|---|---|
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan | 1989 |
Albumin synthesis rates measured with [2H5ring]phenylalanine are not responsive to short-term intravenous nutrients in healthy humans.
Topics: Adult; Blood Glucose; Blood Proteins; Cross-Over Studies; Deuterium; Humans; Insulin; Kinetics; Male; Parenteral Nutrition; Phenylalanine; Prealbumin; Serum Albumin; Sodium Chloride; Transferrin | 1995 |
Phenylalanine and tyrosine metabolism in neonates receiving parenteral nutrition differing in pattern of amino acids.
Topics: Amino Acids; Carbon Isotopes; Deuterium; Female; Humans; Hydroxylation; Infant Food; Infant Nutritional Physiological Phenomena; Infant, Newborn; Kinetics; Male; Nutritional Requirements; Oxidation-Reduction; Parenteral Nutrition, Total; Phenylalanine; Tyrosine | 1998 |
Postexercise net protein synthesis in human muscle from orally administered amino acids.
Topics: Administration, Oral; Adult; Amino Acids; Amino Acids, Essential; Deuterium; Female; Humans; Leucine; Lysine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Physical Exertion | 1999 |
Intense exercise stimulates albumin synthesis in the upright posture.
Topics: Adult; Deuterium; Exercise; Female; Gas Chromatography-Mass Spectrometry; Humans; Kinetics; Male; Oxygen Consumption; Phenylalanine; Plasma Volume; Posture; Serum Albumin; Supine Position | 2000 |
Growth hormone does not affect albumin synthesis in the critically ill.
Topics: Adult; Aged; Aged, 80 and over; APACHE; Critical Illness; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Growth Hormone; Humans; Intensive Care Units; Liver; Liver Function Tests; Male; Middle Aged; Phenylalanine; Prospective Studies; Serum Albumin; Sweden | 2001 |
Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise.
Topics: Administration, Oral; Adult; Amino Acids, Essential; Biopsy; Blood Flow Velocity; Carbohydrates; Deuterium; Dietary Supplements; Female; Humans; Infusions, Intravenous; Insulin; Leg; Male; Muscle, Skeletal; Phenylalanine; Physical Exertion; Protein Biosynthesis; Regional Blood Flow; Time Factors | 2001 |
Effect of ibuprofen and acetaminophen on postexercise muscle protein synthesis.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Deuterium; Double-Blind Method; Exercise; Humans; Ibuprofen; Kinetics; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Placebos | 2002 |
Enteral glutamine stimulates protein synthesis and decreases ubiquitin mRNA level in human gut mucosa.
Topics: Adult; Amino Acids; Calpain; Carbon Isotopes; Cathepsin D; Deuterium; Duodenum; Enteral Nutrition; Female; Gas Chromatography-Mass Spectrometry; Glutamine; Humans; Insulin; Intestinal Mucosa; Intubation, Gastrointestinal; Leucine; Male; Phenylalanine; Protein Biosynthesis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ubiquitin | 2003 |
Effect of carbohydrate intake on net muscle protein synthesis during recovery from resistance exercise.
Topics: Adult; Area Under Curve; Blood Glucose; Carbon Isotopes; Deuterium; Dietary Carbohydrates; Exercise; Female; Humans; Insulin; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine | 2004 |
Impairment of phenylalanine conversion to tyrosine in end-stage renal disease causing tyrosine deficiency.
Topics: Adult; Aged; Deuterium; Humans; Hydrocortisone; Insulin; Insulin-Like Growth Factor I; Kidney Failure, Chronic; Middle Aged; Nitrogen Isotopes; Phenylalanine; Tyrosine | 2004 |
Human soleus and vastus lateralis muscle protein metabolism with an amino acid infusion.
Topics: Adaptor Proteins, Signal Transducing; Adult; Amino Acids; Amino Acids, Essential; Biopsy; Carrier Proteins; Cell Cycle Proteins; Deuterium; Electrolytes; Female; Glucose; Humans; Infusions, Intravenous; Male; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Myofibrils; Myosin Heavy Chains; Parenteral Nutrition Solutions; Phenylalanine; Phosphoproteins; Phosphorylation; Protein Biosynthesis; Protein Isoforms; Ribosomal Protein S6 Kinases, 70-kDa; Sarcoplasmic Reticulum; Solutions | 2005 |
Protein metabolism in Turner syndrome and the impact of hormone replacement therapy.
Topics: Adult; Body Composition; Calorimetry, Indirect; Cross-Over Studies; Deuterium; Energy Metabolism; Estrogens; Female; Hormone Replacement Therapy; Humans; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; Progesterone; Proteins; Turner Syndrome; Tyrosine; Young Adult | 2007 |
Amino acid absorption and subsequent muscle protein accretion following graded intakes of whey protein in elderly men.
Topics: Aged; Aging; Algorithms; Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Digestion; Humans; Insulin; Intestinal Absorption; Kinetics; Male; Milk Proteins; Muscle Proteins; Oxidation-Reduction; Phenylalanine; Postprandial Period; Quadriceps Muscle; Tyrosine; Whey Proteins | 2012 |
Enteral delivery of proteins stimulates protein synthesis in human duodenal mucosa in the fed state through a mammalian target of rapamycin-independent pathway.
Topics: Adult; Carbon Isotopes; Deuterium; Dietary Proteins; Duodenum; Enteral Nutrition; Extracellular Signal-Regulated MAP Kinases; Glutamine; Humans; Hyperinsulinism; Intestinal Mucosa; Leucine; Male; Phenylalanine; Phosphatidylinositol 3-Kinase; Phosphorylation; Postprandial Period; Protein Biosynthesis; Protein Processing, Post-Translational; TOR Serine-Threonine Kinases; Up-Regulation; Young Adult | 2013 |
197 other study(ies) available for phenylalanine and deuterium
| Article | Year |
|---|---|
Synthesis of stereospecifically deuterated phenylalamines and determination of their configuration.
Topics: Amino Acid Oxidoreductases; Cinnamates; D-Amino-Acid Oxidase; Deuterium; Fourier Analysis; Isotope Labeling; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Propionates; Stereoisomerism | 1977 |
Mechanistic features of the D-amino acid oxidase reaction studied by double stopped flow spectrophotometry.
Topics: Alanine; Benzoates; D-Amino-Acid Oxidase; Deuterium; Kinetics; Light; ortho-Aminobenzoates; Oxidation-Reduction; Phenylalanine; Spectrophotometry; Structure-Activity Relationship | 1977 |
Studies on the phenylalanine hydroxylase system in vivo. An in vivo assay based on the liberation of deuterium or tritium into the body water from ring-labeled L-phenylalanine.
Topics: Animals; Body Water; Deuterium; Fenclonine; Isotope Labeling; Kinetics; Methotrexate; Molecular Conformation; Phenylalanine; Phenylalanine Hydroxylase; Rats; Spectrophotometry, Ultraviolet; Time Factors; Tritium | 1975 |
NMR investigation of proton exchange in transfer RNA by high resolution NMR.
Topics: Deuterium; Hydrogen-Ion Concentration; Leucine; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Phenylalanine; RNA, Transfer; Saccharomyces cerevisiae; Solvents; Temperature; Tritium; Water | 1975 |
Selectively deuterated amino acid analogues. Synthesis, incorporation into proteins and NMR properties.
Topics: Amino Acids; Bacterial Proteins; Chemical Phenomena; Chemistry; Deuterium; Enzyme Repression; Escherichia coli; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1977 |
Kinetic studies with the use of proton-magnetic-resonance spectroscopy of the specific alpha-deuteration of amino acids by Escherichia coli aspartate aminotransferase.
Topics: Aspartate Aminotransferases; Aspartic Acid; Deuterium; Escherichia coli; Kinetics; Magnetic Resonance Spectroscopy; Phenylalanine | 1978 |
Pulsed FT-NMR double resonance studies of yeast tRNAPhe: specific nuclear Overhauser effects and reinterpretation of low temperature relaxation data.
Topics: Deuterium; Imines; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Phenylalanine; Protons; RNA, Transfer; Saccharomyces cerevisiae; Solvents; Temperature; Water | 1978 |
Selective substitution of 2H and 3H into aromatic amino acids catalyzed by Raney nickel.
Topics: Chemical Phenomena; Chemistry; Deuterium; Magnetic Resonance Spectroscopy; Nickel; Phenylalanine; Tritium; Tryptophan; Tyrosine | 1979 |
Sensitive in vivo assay of the phenylalanine hydroxylating system with a small intravenous dose of heptadeutero L-phenylalanine using high pressure liquid chromatography and capillary gas chromatography/mass fragmentography.
Topics: Adult; Amino Acid Metabolism, Inborn Errors; Chromatography, High Pressure Liquid; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Infant; Isotope Labeling; Male; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias | 1979 |
In vivo metabolism of deutero-L-phenylalanine and deutero-L-tyrosine in normal and in various tumor-bearing rats.
Topics: Animals; Biopterins; Deuterium; Female; Hydroxylation; Kinetics; Liver Neoplasms, Experimental; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Sarcoma, Experimental; Tyrosine | 1977 |
The labelling of urinary acids after oral doses of deuterated L-phenylalanine and L-tyrosine in normal subjects. Quantitative studies with implications for the deuterated phenylalanine load test in phenylketonuria.
Topics: Acids; Adult; Amino Acids; Deuterium; Female; Humans; Male; Phenylalanine; Phenylketonurias; Time Factors; Tyrosine | 1978 |
In vivo determination of phenylalanine hydroxylase activity using heptadeutero-phenylalanine and comparison to the in vitro assay values.
Topics: Deuterium; Diagnosis, Differential; Humans; Methods; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias | 1978 |
Synthesis of specific deuterium labeled tyrosine and phenylalanine derivatives and their use in the total synthesis of [8-arginine]vasopressin derivatives: The separation of diastereomeric [8-arginine]vasopressin derivatives by partition chromatography1,2
Topics: Arginine Vasopressin; Chromatography; Deuterium; Isotope Labeling; Phenylalanine; Stereoisomerism; Tyrosine; Vasopressins | 1977 |
The formation of meta-hydroxyphenylacetic acid through a direct ring hydroxylation reaction in humans.
Topics: Adult; Child; Deuterium; Humans; Kinetics; Mass Spectrometry; Phenylacetates; Phenylalanine; Phenylketonurias | 1977 |
Studies of the reactions of lamb liver serine hydroxymethylase with L-phenylalanine: kinetic isotope effects upon quinonoid intermediate formation.
Topics: Animals; Deuterium; Glycine Hydroxymethyltransferase; Kinetics; Liver; Mathematics; Phenylalanine; Protein Binding; Quinones; Sheep; Spectrophotometry; Transferases | 1977 |
Preparation of selectively deuterated aromatic amino acids for use in 1H NMR studies of proteins.
Topics: Deuterium; Histidine; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Tryptophan; Tyrosine | 1976 |
Determination of deuterium-labeled phenylalanine and tyrosine in human plasma with high pressure liquid chromatography and mass spectrometry.
Topics: Chromatography, High Pressure Liquid; Deuterium; Humans; Isotope Labeling; Mass Spectrometry; Phenylalanine; Phenylthiohydantoin; Tyrosine | 1976 |
Conformational analysis of amino acids and peptides using specific isotope substitution. I. Conformation of L-phenylalanylglycine.
Topics: Deuterium; Dipeptides; Glycine; Magnetic Resonance Spectroscopy; Methods; Molecular Conformation; Nitrogen Isotopes; Phenylalanine; Protons; Tritium; Valine | 1975 |
Preparation of phenylalanine-deuterated, and totally 15N-enriched, calmodulins from Trypanosoma brucei, and its application to drug binding studies.
Topics: Animals; Binding Sites; Calmodulin; Deuterium; Imidazoles; Magnetic Resonance Spectroscopy; Molecular Structure; Nitrogen Isotopes; Phenylalanine; Trypanosoma brucei brucei | 1991 |
Identification and quantitation of phenylalanine, tyrosine and dihydroxyphenylalanine in the thoracic nervous system of the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry.
Topics: Animals; Deuterium; Dihydroxyphenylalanine; Female; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Grasshoppers; Male; Nervous System; Phenylalanine; Propanols; Thorax; Tyrosine | 1990 |
In vivo enzyme activity in inborn errors of metabolism.
Topics: Adult; Bicarbonates; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Hydroxylation; Isotope Labeling; Leucine; Male; Malonates; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methylmalonic Acid; Oxidation-Reduction; Phenylalanine; Phenylketonurias; Propionates; Radioisotope Dilution Technique; Reference Values; Tyrosine | 1990 |
Substitution of Tyr254 with Phe at the active site of flavocytochrome b2: consequences on catalysis of lactate dehydrogenation.
Topics: Binding Sites; Catalysis; Deuterium; Fungal Proteins; Hydroxybutyrates; L-Lactate Dehydrogenase; L-Lactate Dehydrogenase (Cytochrome); Lactates; Lactic Acid; Models, Molecular; Phenylalanine; Protein Conformation; Pyruvates; Saccharomyces cerevisiae; Tyrosine | 1990 |
Phenylalanine flux in adult men: estimates with different tracers and route of administration.
Topics: Adult; Carbon Isotopes; Deuterium; Humans; Infusions, Intravenous; Intubation, Gastrointestinal; Male; Nitrogen Isotopes; Phenylalanine | 1990 |
Metabolic conversion of L-[U-14C]phenylalanine to respiratory 14CO2 in healthy subjects, phenylketonuria heterozygotes and classic phenylketonurics.
Topics: Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Deuterium; Heterozygote; Humans; Hydroxylation; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Mechanistic deductions from kinetic isotope effects and pH studies of pyridoxal phosphate dependent carbon-carbon lyases: Erwinia herbicola and Citrobacter freundii tyrosine phenol-lyase.
Topics: Alanine; Binding, Competitive; Citrobacter; Cysteine; Deuterium; Erwinia; Hydrogen-Ion Concentration; Kinetics; Lyases; Phenylalanine; Pyridoxal Phosphate; Tyrosine; Tyrosine Phenol-Lyase | 1988 |
Probing the functional role of phenylalanine-31 of Escherichia coli dihydrofolate reductase by site-directed mutagenesis.
Topics: Amino Acids; Binding Sites; Deuterium; Escherichia coli; Folic Acid; Hydrogen-Ion Concentration; Kinetics; Mutation; NADP; Phenylalanine; Plasmids; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Tyrosine; Valine | 1987 |
The NIH-shift in the in vivo hydroxylation of ring-deuterated L-phenylalanine in man.
Topics: Adult; Biotransformation; Deuterium; Genetic Carrier Screening; Humans; Hydroxylation; Isotope Labeling; Phenylalanine; Phenylketonurias; Tyrosine | 1986 |
Use of nitrogen-15 and deuterium isotope effects to determine the chemical mechanism of phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Deuterium; Isotope Labeling; Kinetics; Mathematics; Nitrogen Isotopes; Phenylalanine; Phenylalanine Ammonia-Lyase; Radioisotope Dilution Technique; Rhodotorula; Substrate Specificity | 1985 |
Oral versus intravenous L-phenylalanine loading compared by simultaneous application of L-[2H5] and L-[15N]phenylalanine.
Topics: Administration, Oral; Adult; Deuterium; Female; Humans; Infusions, Parenteral; Kinetics; Male; Nitrogen Isotopes; Phenylalanine; Tyrosine | 1985 |
Interaction of heavy meromyosin with substrate. IV. Studies on the tyrosine and tryptophan residues by solvent perturbation method.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Chemical Phenomena; Chemistry; Deuterium; Esters; Glycerol; Glycols; Methods; Muscle Proteins; Optical Rotatory Dispersion; Phenylalanine; Solvents; Spectrophotometry; Sucrose; Tryptophan; Tyrosine; Ultraviolet Rays | 1971 |
Protein conformational transitions in the erythrocyte membrane.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Alcohols; Caseins; Cell Membrane; Deuterium; Edetic Acid; Enzyme Activation; Erythrocytes; Freeze Drying; Humans; Hydrolysis; Infrared Rays; Inosine Nucleotides; Lysine; Magnesium; Myoglobin; Peptides; Phenylalanine; Phosphorus Isotopes; Potassium; Protein Conformation; Protein Hydrolysates; Serine; Sodium; Spectrophotometry | 1971 |
Density-labelling evidence for the phytochrome-mediated activation of phenylalanine ammonia-lyase in mustard cotyledons.
Topics: Acid Phosphatase; Ammonia-Lyases; Centrifugation, Density Gradient; Chromatography, Gel; Cytochromes; Deuterium; Enzyme Activation; Light; Lighting; Phenylalanine; Plant Proteins; Plants; Spectrophotometry; Time Factors; Tritium | 1974 |
Density-labelling evidence for the blue-light-mediated activation of phenylalanine ammonia lyase in Cucumis sativus seedlings.
Topics: Acid Phosphatase; Ammonia-Lyases; Centrifugation, Density Gradient; Cycloheximide; Darkness; Deuterium; Light; Lighting; Phenylalanine; Plants; Spectrophotometry; Time Factors | 1974 |
A novel approach for studies of the molecular conformations in flexible polypeptides.
Topics: Alanine; Calorimetry; Carbon Isotopes; Deuterium; Dimethyl Sulfoxide; Evaluation Studies as Topic; Kinetics; Magnetic Resonance Spectroscopy; Methods; Oligopeptides; Peptides; Phenylalanine; Proline; Protein Conformation; Structure-Activity Relationship; Thermodynamics | 1974 |
Some molecular properties of the elongation factor EF1 from wheat embryos.
Topics: Carbon Radioisotopes; Chromatography; Chromatography, Gel; Deuterium; Electrophoresis, Disc; Guanosine Triphosphate; Hydroxyapatites; Molecular Weight; Peptide Elongation Factors; Phenylalanine; Plants; Protein Biosynthesis; Ribosomes; RNA, Transfer; Sodium Dodecyl Sulfate; Triticum; Tritium; Ultracentrifugation | 1974 |
Mono- and bideuterated L-phenylalanines.
Topics: Borohydrides; Chromatography, Ion Exchange; Deuterium; Isotope Labeling; Mass Spectrometry; Methods; Optical Rotation; Phenylalanine | 1974 |
High-resolution proton magnetic resonance studies of two trypsin inhibitors: soybean trypsin inhibitor (Kunitz) and ovomucoid (hen egg white).
Topics: Binding Sites; Computers; Deuterium; Egg Proteins; Egg White; Glycine; Glycine max; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mathematics; Phenylalanine; Protein Binding; Protein Conformation; Trypsin Inhibitors; Tyrosine | 1973 |
Topology and growth of the intracytoplasmic membrane system of Rhodopseudomonas spheroides: protein, chlorophyll, and phospholipid insertion into steady-state anaerobic cells.
Topics: Acetates; Anaerobiosis; Bacterial Chromatophores; Bacterial Proteins; Carbon Radioisotopes; Centrifugation, Density Gradient; Chlorophyll; Culture Media; Deuterium; Leucine; Levulinic Acids; Microscopy, Electron; Models, Biological; Ornithine; Oxides; Phenylalanine; Phospholipids; Rhodobacter sphaeroides; Stereoisomerism; Tritium; Water | 1974 |
Studies on the catalytic mechanism of pepsin using a new synthetic substrate.
Topics: Acetophenones; Animals; Azo Compounds; Bromine; Catalysis; Deuterium; Endopeptidases; Fluoroacetates; Glycine; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Models, Chemical; Pepsin A; Phenylalanine; Protein Binding; Structure-Activity Relationship; Swine; Tryptophan; Tyrosine | 1972 |
Raman studies of nucleic acids. VI. Conformational structures of tRNA fMet , tRNA Val and tRNA Phe 2 .
Topics: Chemical Precipitation; Deuterium; Escherichia coli; Ethanol; Formates; Lasers; Magnesium; Methionine; Nucleic Acid Conformation; Nucleic Acid Denaturation; Phenylalanine; Ribonucleotides; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer; Spectrum Analysis; Temperature; Valine | 1972 |
Production of 2-phenethyl alcohol and 2-phenyllactic acid in Candida species.
Topics: Benzene Derivatives; Candida; Candida albicans; Carbon Radioisotopes; Chromatography, Paper; Deuterium; Drug Stability; Ethanol; Lactates; Magnetic Resonance Spectroscopy; Molecular Conformation; Optical Rotation; Peptones; Phenylalanine; Species Specificity; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1974 |
Effects of dilute HCl on yeast tRNAPhe and E. coli tRNA1fMet.
Topics: Computers; Deuterium; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Formates; Hydrochloric Acid; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Methionine; Nucleic Acid Conformation; Optical Rotation; Phenylalanine; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Solubility; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Enzymatic acylation of oxidized-reduced transfer ribonucleic acid by Escherichia coli, yeast, and rat liver synthetases occurs almost exclusively at the 2'-hydroxyl.
Topics: Amino Acyl-tRNA Synthetases; Animals; Carbon Radioisotopes; Chromatography, Thin Layer; Deuterium; Escherichia coli; Fourier Analysis; Hydrogen-Ion Concentration; Isomerism; Kinetics; Liver; Magnetic Resonance Spectroscopy; Oxidation-Reduction; Phenylalanine; Rats; RNA, Bacterial; RNA, Transfer; Saccharomyces cerevisiae; Species Specificity; Time Factors; Valine | 1974 |
Pathogenesis of phenylketonuria: inhibition of DOPA and catecholamine synthesis in patients with phenylketonuria.
Topics: Amino Acid Metabolism, Inborn Errors; Catecholamines; Catechols; Child; Child, Preschool; Deuterium; Dihydroxyphenylalanine; Dopamine; Glycols; Homovanillic Acid; Humans; Mass Spectrometry; Phenylalanine; Phenylketonurias; Tyrosine; Vanilmandelic Acid | 1972 |
Studies of enzyme-mediated reactions. I. Syntheses of deuterium- or tritium-labelled (3S)-and (3R)-phenylalanines: stereochemical course of the elimination catalysed by L-phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Deuterium; Isotope Labeling; Phenylalanine; Stereoisomerism; Tritium | 1972 |
Deuterium isotope effect in enzymatic transamination of L-deuterio-phenylalanine to deuterio-phenylpyruvic acid.
Topics: Amination; Animals; Brain Chemistry; Cell Wall; Chromatography, Ion Exchange; Chromatography, Thin Layer; Deuterium; Eukaryota; Hydrolysis; Kinetics; Leucine; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenylalanine; Phenylpyruvic Acids; Rats; Spectrophotometry, Infrared; Spectrum Analysis; Time Factors | 1973 |
Formation of phenols from aromatic substrates by plant and animal mono-oxygenases: the effect of adjacent deuteriums on the magnitude of the NIH shift of tritium.
Topics: Acetanilides; Animals; Anisoles; Carbon Isotopes; Cinnamates; Deuterium; Hydroxylation; In Vitro Techniques; Male; Microsomes; Microsomes, Liver; Oxygenases; Phenobarbital; Phenols; Phenylalanine; Plant Cells; Plants; Proteins; Rats; Tritium | 1973 |
Conformation of antamanide-sodium in solution.
Topics: Amines; Antitoxins; Carbon Isotopes; Circular Dichroism; Cyanides; Deuterium; Glycine; Hydrogen; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Peptides, Cyclic; Phenylalanine; Proline; Protons; Sodium; Solutions; Spectrum Analysis; Temperature; Thiocyanates | 1973 |
Stereoselective -labelling of aromatic amino-acids with deuterium and tritium.
Topics: Amines; Aspartic Acid; Carbon Isotopes; Chemical Phenomena; Chemistry; Cinnamates; Deuterium; Hydroxylation; Isotope Labeling; Methods; Phenylalanine; Tritium; Tyrosine | 1973 |
Stereochemistry of ammonia elimination from L-tyrosine with L-phenylalanine ammonia-lyase.
Topics: Ammonia-Lyases; Binding Sites; Chymotrypsin; Deuterium; Magnetic Resonance Spectroscopy; Mitosporic Fungi; Optical Rotation; Phenylalanine; Stereoisomerism; Tritium; Tyrosine | 1973 |
Inhibition of alpha-chymotrypsin by hydroxymethyl analogues of D-and L-N-acetylphenylalanine and N-acetyltryptophan of potential affinity labeling value.
Topics: Acetates; Binding Sites; Binding, Competitive; Chromatography, Paper; Chymotrypsin; Deuterium; Isomerism; Kinetics; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methanol; Optical Rotation; Phenylalanine; Protein Binding; Spectrophotometry, Infrared; Structure-Activity Relationship; Tryptophan | 1974 |
Functional activity of ribosomes formed in vivo from "relaxed particles".
Topics: Carbon Isotopes; Centrifugation, Zonal; Deuterium; Escherichia coli; Methionine; Mutation; Nitrogen; Nutritional Physiological Phenomena; Peptide Biosynthesis; Phenylalanine; Radioisotopes; Ribosomes; Spectrophotometry; Tritium | 1967 |
Complementation in vitro of phenylalanyl-tRNA synthetases of Escherichia coli.
Topics: Antigen-Antibody Reactions; Antigens; Carbon Isotopes; Cell-Free System; Centrifugation, Density Gradient; Cross Reactions; Deuterium; Escherichia coli; Immune Sera; Kinetics; Ligases; Mutation; Phenylalanine; RNA, Bacterial; RNA, Transfer; Temperature | 1970 |
On the mechanism of the pepsin-catalyzed exchange of carboxylic acids with water-18O.
Topics: Acids; Catalysis; Chemical Phenomena; Chemistry; Chymotrypsin; Deuterium; Hydrogen-Ion Concentration; Kinetics; Oxygen Isotopes; Pepsin A; Phenylalanine; Water | 1970 |
Some aspects of phenylalanine incorporation in deuterium oxide (D20) substitution for water (H20) in polyuridylic acid-directed ribosomal protein biosynthesis.
Topics: Deuterium; Escherichia coli; Phenylalanine; Protein Biosynthesis; Ribosomes; Uracil Nucleotides; Water | 1970 |
Studies on the Bacillus subtilis neutral-protease- and Bacillus thermoproteolyticus thermolysin-catalyzed hydrolysis of dipeptide substrates.
Topics: Acrylates; Bacillus; Bacillus subtilis; Deuterium; Dipeptides; Furans; Hydrogen-Ion Concentration; Kinetics; Leucine; Peptide Hydrolases; Phenylalanine; Spectrophotometry | 1970 |
Optical activity and solvent perturbation of fumarase.
Topics: Adipates; Animals; Circular Dichroism; Deuterium; Fumarates; Glutarates; Glycerol; Hydro-Lyases; Malonates; Myocardium; Optical Rotatory Dispersion; Osmolar Concentration; Phenylalanine; Protein Conformation; Spectrophotometry; Succinates; Swine; Tryptophan; Ultraviolet Rays | 1972 |
The use of deuterated phenylalanine for the elucidation of the phenylalanine-tyrosine metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Chromatography, Gas; Deuterium; Humans; Hydroxylation; Infant; Lactates; Mass Spectrometry; Methods; Phenols; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine | 1972 |
NMR studies of organic solvent denatured yeast phenylalanyl transfer RNA at 220 MHZ a.
Topics: Adenosine; Carbon Isotopes; Chromatography, Ion Exchange; Computers; Cytidine; Deuterium; Dimethyl Sulfoxide; Guanosine; Lithium; Magnetic Resonance Spectroscopy; Methylation; Nucleic Acid Denaturation; Phenylalanine; Pyrimidines; RNA, Transfer; Thymidine; Yeasts | 1971 |
Experimental and calculated conformational characteristics of the cyclic decapeptide antamanide.
Topics: 1-Propanol; Alanine; Chemical Phenomena; Chemistry, Physical; Chloroform; Circular Dichroism; Deuterium; Dioxins; Ethanol; Fluorine; Magnetic Resonance Spectroscopy; Mathematics; Methanol; Models, Chemical; Models, Structural; Peptides; Peptides, Cyclic; Phenylalanine; Proline; Protein Conformation; Ultraviolet Rays; Valine | 1971 |
Solubilization of a reticulocyte ribosomal fraction responsible for the decline in ribosomal activity with cell maturation.
Topics: Aging; Animals; Blood Proteins; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Chlorides; Deuterium; Electrophoresis; Hemoglobins; Leucine; Magnesium; Phenylalanine; Polynucleotides; Potassium Chloride; Reticulocytes; Ribonucleases; Ribosomes; RNA, Messenger; RNA, Viral; Serum Albumin, Bovine; Solubility; Spectrophotometry; Time Factors; Tritium; Ultraviolet Rays; Uracil Nucleotides | 1971 |
Synthesis of highly deuterated amino acids.
Topics: Amino Acids; Asparagine; Aspartic Acid; Chemical Phenomena; Chemistry; Deuterium; Eukaryota; Glutamates; Oxytocin; Phenylalanine; Pigments, Biological; Vasopressins | 1966 |
Effect of D2O on the carboxypeptidase-catalyzed hydrolysis of O-(trans-cinnamoyl)-L-beta-phenyllactate and N-(N-benzoylglycyl)-L-phenylalanine.
Topics: Carboxypeptidases; Catalysis; Deuterium; Esters; Peptides; Phenylacetates; Phenylalanine | 1969 |
Studies of the location of the tyrosyl residues in insulin. II.
Topics: Amino Acid Sequence; Animals; Cattle; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Glycerol; Glycols; Hydrogen-Ion Concentration; Insulin; Methanol; Optical Rotatory Dispersion; Oxides; Peptides; Phenylalanine; Spectrophotometry; Spectrum Analysis; Sucrose; Trypsin; Trypsin Inhibitors; Tyrosine; Ultraviolet Rays; Zinc | 1969 |
The biosynthesis of isotope hybrid proteins for high resolution nuclear magnetic resonance studies by incorporation of [1H]amino acids into fully deuterated algae.
Topics: Alanine; Amino Acids; Deuterium; Eukaryota; Hydrogen; Leucine; Magnetic Resonance Spectroscopy; Methionine; Phenylalanine; Protein Biosynthesis; Tyrosine | 1970 |
On the conformation of dipeptides in aqueous solutions.
Topics: Bromides; Chemical Phenomena; Chemistry; Deuterium; Dipeptides; Glycine; Infrared Rays; Leucine; Magnetic Resonance Spectroscopy; Optical Rotatory Dispersion; Phenylalanine; Solutions; Spectrum Analysis; Stereoisomerism; Water | 1970 |
Flavinyl peptides. 3. Studies of intramolecular interactions in flavinyl aromatic amino acids by proton magnetic resonance.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Deuterium; Dimethyl Sulfoxide; Esters; Flavins; Magnetic Resonance Spectroscopy; Models, Structural; Peptides; Phenylalanine; Temperature; Tryptophan; Tyrosine | 1970 |
The conformation of gramicidin S and its N,N'-diacetyl derivative in solutions.
Topics: Acetates; Chloroform; Deuterium; Infrared Rays; Leucine; Magnetic Resonance Spectroscopy; Models, Structural; Optical Rotatory Dispersion; Ornithine; Phenylalanine; Solvents; Stereoisomerism; Tyrothricin; Valine | 1970 |
Studies related to the chemistry of melanins. IX. Syntheses of specifically deuteriated 3,4-dihydroxyphenethylamines and (plus or minus)-3,4-dihydroxyphenylalanines.
Topics: Chemical Phenomena; Chemistry; Deuterium; Melanins; Phenethylamines; Phenylalanine | 1970 |
Studies on the conformation of the anticodon loop of phenylalanine transfer ribonucleic acid. Effect of environment on the fluorescence of the Y base.
Topics: Chemical Phenomena; Chemistry; Circular Dichroism; Deuterium; Fluorescence; Genetic Code; Magnesium; Pancreas; Phenylalanine; Polynucleotides; Ribonucleases; RNA, Transfer; Seeds; Spectrophotometry; Temperature; Triticum; Yeasts | 1970 |
Deuteriation and tritiation of aryl aldehydes in the formyl group and the synthesis of (plus or minus)-3,4-dihydroxy(beta-2H2)phenylalanine.
Topics: Aldehydes; Deuterium; Morpholines; Nitriles; Phenylalanine; Radiochemistry; Tritium | 1970 |
Laser-excited Raman spectroscopy of biomolecules. II. Native ribonuclease and alpha-chymotrypsin.
Topics: Amides; Amino Acids; Animals; Cattle; Chemical Phenomena; Chemistry; Chymotrypsin; Cystine; Deuterium; Glutamates; Histidine; Hydrogen-Ion Concentration; Lasers; Muramidase; Peptides; Phenylalanine; Protein Denaturation; Ribonucleases; Spectrum Analysis; Sulfides; Tryptophan; Tyrosine | 1970 |
Proton magnetic resonance studies of oligopeptides containing aromatic residues.
Topics: Deuterium; Dimethyl Sulfoxide; Dipeptides; Histidine; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Peptides; Phenylalanine; Protein Denaturation; Proteins; Protons; Tryptophan; Tyrosine | 1971 |
Nuclear magnetic resonance studies of side-chain interactions in polyamino acids with aromatic groups. Comparison to conformational energy calculations.
Topics: Amino Acids; Aspartic Acid; Benzyl Compounds; Chemical Phenomena; Chemistry; Deuterium; Fluoroacetates; Glutamates; Magnetic Resonance Spectroscopy; Models, Structural; Phenylalanine; Polymers | 1971 |
Conformational study of gramicidin S using the phthalimide group as nuclear magnetic resonance marker.
Topics: Chemical Phenomena; Chemistry; Deuterium; Imides; Magnetic Resonance Spectroscopy; Models, Structural; Ornithine; Peptides; Phenylalanine; Phthalic Acids; Protons; Tyrothricin | 1968 |
The effects of selected chemical agents on furrow induction in the eggs of Arbacia punctualata.
Topics: Animals; Antimetabolites; Colchicine; Dactinomycin; Depression, Chemical; Deuterium; Echinodermata; Female; In Vitro Techniques; Mercaptoethanol; Ovum; Phenylalanine; Puromycin | 1968 |
A ssay of L-phenylalaine:2-oxoglutarate aminotransferase by determination of phenyl pyruvate.
Topics: Deuterium; Drug Stability; Hydrogen-Ion Concentration; Ketoglutaric Acids; Magnetic Resonance Spectroscopy; Methods; Phenylalanine; Phenylpyruvic Acids; Spectrophotometry; Transaminases | 1969 |
Location of hydrogen transfer steps in the mechanism of reduction of L-amino acid oxidase.
Topics: Amino Acid Oxidoreductases; Chemical Phenomena; Chemistry; Deuterium; Flavin-Adenine Dinucleotide; Glycine; Hydrogen; Kinetics; Phenylalanine; Spectrophotometry; Tritium; Tyrosine | 1969 |
The spatial location of chromophoric residues in L-glutamate dehydrogenase.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Glucose; Glutamate Dehydrogenase; Glycerol; Glycols; Phenylalanine; Spectrophotometry; Tryptophan; Tyrosine | 1966 |
Stereospecific catalytic labelling of amino-acids and mandelic acid with isotopic hydrogen.
Topics: Alanine; Catalysis; Deuterium; Mandelic Acids; Phenylalanine | 1966 |
The conformational stability of alpha-helical nonpolar polypeptides in solution.
Topics: Chemical Phenomena; Chemistry, Physical; Deuterium; Leucine; Peptides; Phenylalanine; Solutions; Thermodynamics | 1966 |
Retention of deuterium in p-tyrosine formed enzymatically from p-deuterophenylalanine.
Topics: Benzoates; Deuterium; Magnetic Resonance Spectroscopy; Mixed Function Oxygenases; Phenylalanine; Pseudomonas; Spectrum Analysis; Tyrosine | 1966 |
Quantitative studies on the hydroxylation-induced migration of deuterium and tritium during phenylalanine hydroxylation.
Topics: Animals; Chemical Phenomena; Chemistry; Deuterium; Liver; Mixed Function Oxygenases; Models, Biological; Phenylalanine; Pseudomonas; Rats; Tritium | 1967 |
Detection of heterozygous carriers for phenylketonuria by a L-[2H5]phenylalanine stable isotope loading test.
Topics: Deuterium; Female; Genetic Carrier Screening; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine | 1984 |
The use of deuterated phenylalanine for the in vivo assay of phenylalanine hydroxylase activity in children.
Topics: Child; Child, Preschool; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Infant; Phenylalanine; Phenylalanine Hydroxylase; Time Factors; Tyrosine | 1982 |
Stereospecificity of phenylalanine plasma kinetics and hydroxylation in man following oral application of a stable isotope-labelled pseudo-racemic mixture of L- and D-phenylalanine.
Topics: Adult; Chromatography, High Pressure Liquid; Deuterium; Humans; Hydroxylation; Kinetics; Mass Spectrometry; Nitrogen Isotopes; Phenylalanine; Stereoisomerism; Tyrosine | 1983 |
NMR studies of the interaction of gene-V protein of bacteriophage M13 with oligonucleotides.
Topics: Coliphages; Deuterium; Magnetic Resonance Spectroscopy; Oligodeoxyribonucleotides; Oligonucleotides; Phenylalanine; Viral Proteins | 1980 |
2H NMR demonstration of amino acid - nucleotide interactions.
Topics: Adenosine Monophosphate; Chemical Phenomena; Chemistry; Deuterium; Kinetics; Magnetic Resonance Spectroscopy; Mathematics; Phenylalanine; Poly A | 1982 |
The conversion of phenylalanine to tyrosine in man. Direct measurement by continuous intravenous tracer infusions of L-[ring-2H5]phenylalanine and L-[1-13C] tyrosine in the postabsorptive state.
Topics: Absorption; Adult; Carbon Isotopes; Deuterium; Humans; Infusions, Parenteral; Isotope Labeling; Male; Phenylalanine; Tyrosine | 1982 |
Dynamics of amino acid side chains in membrane proteins by high field solid state deuterium nuclear magnetic resonance spectroscopy. Phenylalanine, tyrosine, and tryptophan.
Topics: Bacteriorhodopsins; Carotenoids; Deuterium; Halobacterium; Magnetic Resonance Spectroscopy; Membrane Proteins; Phenylalanine; Protein Conformation; Tryptophan; Tyrosine | 1981 |
Enzymatic-chemical preparation of quinoxaline derivatives from L-amino acids for gas chromatographic-mass spectrometric analyses.
Topics: Amino Acid Oxidoreductases; Amino Acids; Carbon Isotopes; Chromatography, Ion Exchange; Deuterium; Gas Chromatography-Mass Spectrometry; Humans; Indicators and Reagents; Isotope Labeling; Phenylalanine; Quinoxalines; Sensitivity and Specificity | 1995 |
Whole body and splanchnic leucine, phenylalanine, and glucose kinetics during endotoxemia in humans.
Topics: Acute-Phase Proteins; Adult; Blood Glucose; Carbon Isotopes; Deuterium; Endotoxins; Escherichia coli; Glucose; Humans; Isotope Labeling; Kinetics; Leucine; Male; Phenylalanine; Proteins; Splanchnic Circulation; Toxemia | 1994 |
Characterization of enzyme-bound ligand dynamics by solid-state NMR in the presence of ligand exchange: L-phenylalanine on carboxypeptidase A.
Topics: Binding Sites; Biophysical Phenomena; Biophysics; Carboxypeptidases; Carboxypeptidases A; Crystallization; Deuterium; In Vitro Techniques; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Structure; Phenylalanine | 1995 |
Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase.
Topics: Animals; Chromobacterium; Cloning, Molecular; Deuterium; Escherichia coli; Hydroxylation; Iron; Isotope Labeling; Kinetics; Liver; Metalloproteins; Metals; Nonheme Iron Proteins; Phenylalanine; Phenylalanine Hydroxylase; Rats; Recombinant Proteins; Spectrophotometry, Ultraviolet; Substrate Specificity | 1995 |
Regulation of postprandial whole-body proteolysis in insulin-deprived IDDM.
Topics: Adult; Amino Acids; Blood Glucose; Deuterium; Diabetes Mellitus, Type 1; Fatty Acids, Nonesterified; Female; Food; Food, Formulated; Humans; Hydrogen-Ion Concentration; Insulin; Kinetics; Leucine; Male; Middle Aged; Phenylalanine; Proteins | 1995 |
Response of protein synthesis in human skeletal muscle to insulin: an investigation with L-[2H5]phenylalanine.
Topics: Adult; Animals; Deuterium; Gas Chromatography-Mass Spectrometry; Glucose Clamp Technique; Humans; Insulin; Male; Muscle Proteins; Muscles; Phenylalanine; Rats; Tritium | 1994 |
Plasma and urine enrichments following infusion of L-[1-13C]phenylalanine and L-[ring-2H5]phenylalanine in humans: evidence for an isotope effect in renal tubular reabsorption.
Topics: Adult; Carbon Isotopes; Deuterium; Humans; Infusions, Intravenous; Kidney Tubules; Male; Phenylalanine | 1994 |
Use of 18O-labelled leucine and phenylalanine to measure protein turnover in muscle cell cultures and possible futile cycling during aminoacylation.
Topics: Acylation; Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Deuterium; Kinetics; Leucine; Muscle Proteins; Muscles; Oxygen Isotopes; Phenylalanine; Swine | 1993 |
Improved synthetic methods for the selective deuteration of aromatic amino acids: applications of selective protonation towards the identification of protein folding intermediates through nuclear magnetic resonance.
Topics: Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Phenylalanine; Protein Folding; Proteins; Protons; Thioredoxins; Tryptophan | 1993 |
An isotopic study of the effect of dietary carbohydrate on the metabolic fate of dietary leucine and phenylalanine.
Topics: Adult; Blood Glucose; Carbon Isotopes; Deuterium; Diet; Dietary Carbohydrates; Humans; Keto Acids; Leucine; Male; Nitrogen Isotopes; Oxidation-Reduction; Phenylalanine; Splanchnic Circulation | 1993 |
Dietary lysine requirement of young adult males determined by oxidation of L-[1-13C]phenylalanine.
Topics: Adult; Carbon Isotopes; Deuterium; Energy Intake; Humans; Isotope Labeling; Lysine; Male; Mathematics; Models, Biological; Nutritional Requirements; Oxidation-Reduction; Phenylalanine | 1993 |
Twenty-four-hour intravenous and oral tracer studies with L-[1-13C]phenylalanine and L-[3,3-2H2]tyrosine at a tyrosine-free, generous phenylalanine intake in adults.
Topics: Administration, Oral; Adult; Carbon Dioxide; Carbon Isotopes; Circadian Rhythm; Deuterium; Humans; Hydroxylation; Injections, Intravenous; Leucine; Male; Oxidation-Reduction; Phenylalanine; Tyrosine | 1996 |
Enteral glutamate is almost completely metabolized in first pass by the gastrointestinal tract of infant pigs.
Topics: Amino Acids; Animals; Carbon Isotopes; Deuterium; Enteral Nutrition; Glutamic Acid; Intestinal Absorption; Isotope Labeling; Kinetics; Phenylalanine; Radioisotope Dilution Technique; Swine; Time Factors | 1996 |
Albumin but not fibrinogen synthesis correlates with galactose elimination capacity in patients with cirrhosis of the liver.
Topics: Adult; Aged; Aminopyrine; Blood Volume; Deuterium; Fibrinogen; Galactose; Gas Chromatography-Mass Spectrometry; Hepatitis B; Hepatitis C; Humans; Kinetics; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Radioisotope Dilution Technique; Serum Albumin | 1996 |
Biosynthesis of the acetylenic compounds in cultured cells of Asparagus officinalis from D- and 13C-labelled phenylalanines.
Topics: Acetylene; Carbon Isotopes; Cells, Cultured; Deuterium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Phenylalanine; Shikimic Acid; Vegetables | 1996 |
Determination of isotopic ratios of L-leucine and L-phenylalanine and their stable isotope labeled analogues in biological samples by gas chromatography/triple-stage quadrupole mass spectrometry.
Topics: Apolipoprotein A-I; Apolipoproteins; Calibration; Carbon Isotopes; Deuterium; Esters; Gas Chromatography-Mass Spectrometry; Leucine; Lipoproteins; Molecular Structure; Phenylalanine | 1996 |
Locations of local anesthetic dibucaine in model membranes and the interaction between dibucaine and a Na+ channel inactivation gate peptide as studied by 2H- and 1H-NMR spectroscopies.
Topics: Amino Acid Sequence; Anesthetics, Local; Animals; Biophysical Phenomena; Biophysics; Cholesterol; Deuterium; Dibucaine; In Vitro Techniques; Liposomes; Magnetic Resonance Spectroscopy; Membrane Lipids; Membranes, Artificial; Models, Molecular; Molecular Structure; Oligopeptides; Palmitic Acids; Phenylalanine; Phosphatidylserines; Protons; Rats; Sodium Channel Blockers; Sodium Channels | 1996 |
Simultaneous measurement of albumin and fibrinogen synthetic rates in normal fasted subjects.
Topics: Aged; Body Mass Index; C-Reactive Protein; Deuterium; Fasting; Female; Fibrinogen; Gas Chromatography-Mass Spectrometry; Humans; Insulin; Kinetics; Liver; Male; Middle Aged; Phenylalanine; Plasma Volume; Serum Albumin | 1996 |
Increased clearance of low density lipoprotein precursors in patients with heterozygous familial defective apolipoprotein B-100: a stable isotope approach.
Topics: Adult; Apolipoprotein B-100; Apolipoproteins B; Carbon Isotopes; Deuterium; Female; Heterozygote; Humans; Kinetics; Leucine; Lipids; Lipoproteins; Lipoproteins, LDL; Male; Metabolic Clearance Rate; Middle Aged; Mutation; Phenylalanine; Protein Precursors | 1996 |
Whole body protein metabolism in children with cancer.
Topics: Adolescent; Amino Acids; Carbon Isotopes; Child; Child, Preschool; Deuterium; Female; Humans; Kinetics; Leucine; Male; Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Tyrosine | 1996 |
Bound ligand motion in crystalline carboxypeptidase A.
Topics: Carboxypeptidases; Carboxypeptidases A; Computer Simulation; Crystallization; Deuterium; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Phenylacetates; Phenylalanine; Phenylpropionates; Protein Conformation; Stereoisomerism | 1997 |
Hepatic protein synthesis in the sheep: effect of intake as monitored by use of stable-isotope-labelled glycine, leucine and phenylalanine.
Topics: Amino Acids; Animals; Apolipoprotein B-100; Apolipoproteins B; Carbon Isotopes; Deuterium; Energy Intake; Glycine; Leucine; Liver; Male; Phenylalanine; Protein Biosynthesis; Sheep | 1997 |
Effect of amino acid and glucose administration during postexercise recovery on protein kinetics in dogs.
Topics: Amino Acids; Animals; Blood Glucose; Deuterium; Dogs; Glucose; Hindlimb; Insulin; Insulin Secretion; Kinetics; Male; Phenylalanine; Physical Conditioning, Animal; Physical Exertion; Proteins; Radioisotope Dilution Technique; Time Factors | 1997 |
Mixed muscle protein synthesis and breakdown after resistance exercise in humans.
Topics: Adult; Biomarkers; Biopsy; Creatine Kinase; Creatinine; Deuterium; Exercise; Female; Humans; Male; Methylhistidines; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; Rest; Time Factors; Urea | 1997 |
Central opiate mu-receptor-mediated suppression of tissue protein synthesis.
Topics: Adenosine Triphosphate; Animals; Bicarbonates; Carbon Dioxide; Cerebral Ventricles; Deuterium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Hydrogen-Ion Concentration; Injections, Intraventricular; Intestinal Mucosa; Kidney; Liver; Male; Muscle, Skeletal; Organ Specificity; Oxygen; Oxyhemoglobins; Partial Pressure; Phenylalanine; Phosphocreatine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Regression Analysis; Respiration; Spleen | 1997 |
Effects of cachexia due to cancer on whole body and skeletal muscle protein turnover.
Topics: Adult; Aged; Blood Proteins; Cachexia; Carbon Isotopes; Carcinoma; Deuterium; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Muscle, Skeletal; Nutrition Disorders; Phenylalanine; Protein Biosynthesis; Proteins; Radiopharmaceuticals; Stomach Neoplasms; Tyrosine | 1998 |
Phenylalanine utilization by the gut and liver measured with intravenous and intragastric tracers in pigs.
Topics: Animals; Deuterium; Digestive System Physiological Phenomena; Eating; Fasting; Liver; Models, Biological; Phenylalanine; Portal System; Protein Biosynthesis; Radioisotope Dilution Technique; Splanchnic Circulation; Swine | 1997 |
[Detection of human proteins in vivo!].
Topics: Blood Proteins; Carbon Radioisotopes; Deuterium; Humans; Leucine; Metabolism, Inborn Errors; Phenylalanine | 1997 |
Measurement of albumin synthesis in humans using stable isotopes.
Topics: Acidosis; Carbon Isotopes; Deuterium; Humans; Injections, Intravenous; Insulin-Like Growth Factor I; Isotope Labeling; Leucine; Phenylalanine; Reference Values; Serum Albumin | 1997 |
Local control of peptide conformation: stabilization of cis proline peptide bonds by aromatic proline interactions.
Topics: Deuterium; Kinetics; Molecular Conformation; Peptides; Phenylalanine; Proline; Protein Folding; Stereoisomerism; Thermodynamics; Tyrosine | 1998 |
Gut mucosal protein synthesis in fed and fasted humans.
Topics: Adolescent; Adult; Deuterium; Fasting; Food; Gas Chromatography-Mass Spectrometry; Humans; Injections, Intravenous; Intestinal Mucosa; Leucine; Male; Phenylalanine; Protein Biosynthesis; Radioactive Tracers; Reference Values; Stomach | 1998 |
Twenty-four-hour L-[1-(13)C]tyrosine and L-[3,3-(2)H2]phenylalanine oral tracer studies at generous, intermediate, and low phenylalanine intakes to estimate aromatic amino acid requirements in adults.
Topics: Adolescent; Adult; Amino Acids; Carbon Isotopes; Circadian Rhythm; Deuterium; Diet; Female; Humans; Hydroxylation; Kinetics; Male; Nutritional Requirements; Oxidation-Reduction; Phenylalanine; Tyrosine | 1998 |
Increased protein synthesis after acute IGF-I or insulin infusion is localized to muscle in mice.
Topics: Animals; Deuterium; Heart; Infusions, Intravenous; Insulin; Insulin-Like Growth Factor I; Male; Mice; Muscle, Skeletal; Myocardium; Organ Specificity; Phenylalanine; Protein Biosynthesis | 1998 |
Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
Topics: Amino Acid Substitution; Binding Sites; Cobamides; Crystallization; Crystallography, X-Ray; Deuterium; Enzyme Stability; Free Radicals; Kinetics; Methylmalonyl-CoA Mutase; Mutagenesis, Site-Directed; Phenylalanine; Propionibacterium; Tritium; Tyrosine | 1998 |
The behavior of substrate analogues and secondary deuterium isotope effects in the phenylalanine ammonia-lyase reaction.
Topics: Alanine; Cresols; Deuterium; Enzyme Activation; Glycine; Hydrocarbons, Cyclic; Isotope Labeling; Kinetics; Phenylalanine; Phenylalanine Ammonia-Lyase; Pyridines; Substrate Specificity | 1998 |
Vascular sources of phenylalanine, tyrosine, lysine, and methionine for casein synthesis in lactating goats.
Topics: Animals; Carbon Isotopes; Caseins; Deuterium; Female; Goats; Hydroxylation; Kinetics; Lactation; Lysine; Mammary Glands, Animal; Methionine; Phenylalanine; Tyrosine | 1999 |
Protein metabolism in glucagonoma.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine | 1999 |
Phenylalanine hydroxylation across the kidney in humans rapid communication.
Topics: Adult; Deuterium; Female; Hepatic Artery; Hepatic Veins; Humans; Hydroxylation; Kidney; Kinetics; Male; Phenylalanine; Phenylalanine Hydroxylase; Splanchnic Circulation; Tyrosine; Uremia | 1999 |
Identification of the sites of hydroxyl radical reaction with peptides by hydrogen/deuterium exchange: prevalence of reactions with the side chains.
Topics: Deuterium; Dithiothreitol; DNA Footprinting; Enkephalin, Leucine-2-Alanine; Hydrogen; Hydrogen Peroxide; Hydroxyl Radical; Iron; Leucine; Oligopeptides; Oxidation-Reduction; Peptide Fragments; Phenylalanine; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Tyrosine | 2000 |
Probes of a role for remote binding interactions on hydrogen tunneling in the horse liver alcohol dehydrogenase reaction.
Topics: Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding Sites; Deuterium; Horses; Hydrogen; Isoleucine; Kinetics; Liver; Mutagenesis, Site-Directed; Phenylalanine; Recombinant Proteins; Tritium; Tryptophan | 2000 |
Evidence for an NIH shift as the origin of the apparently anomalous distribution of deuterium in estragole from Artemisia dracunculus.
Topics: Allylbenzene Derivatives; Anisoles; Artemisia; Deuterium; Isotope Labeling; Magnetic Resonance Spectroscopy; Oils, Volatile; Phenylalanine; Plants, Medicinal | 2000 |
Measurement of skin protein breakdown in a rat model.
Topics: Animals; Blotting, Western; Carbon Isotopes; Collagen; Deuterium; Electrophoresis, Polyacrylamide Gel; Extracellular Space; Infusions, Intravenous; Intracellular Fluid; Keto Acids; Leucine; Male; Models, Biological; Phenylalanine; Proteins; Rats; Rats, Sprague-Dawley; Skin | 2000 |
Whole body protein kinetics in women: effect of pregnancy and IDDM during anabolic stimulation.
Topics: Amino Acids; Blood Glucose; Carbon Isotopes; Deuterium; Diabetes Mellitus, Type 1; Female; Glucose Clamp Technique; Humans; Hydroxylation; Insulin; Kinetics; Leucine; Oxidation-Reduction; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Proteins | 2000 |
Inter- and intra-molecular migration of peptide amide hydrogens during electrospray ionization.
Topics: Algorithms; Amides; Aspartic Acid; Deuterium; Fourier Analysis; Hydrogen; Oligopeptides; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2001 |
Probes of hydrogen tunneling with horse liver alcohol dehydrogenase at subzero temperatures.
Topics: Acetonitriles; Alcohol Dehydrogenase; Amino Acid Substitution; Animals; Binding, Competitive; Deuterium; Dimethyl Sulfoxide; Dimethylformamide; Ethylene Glycol; Freezing; Horses; Hydrogen; Kinetics; Liver; Methanol; Phenylalanine; Propranolol; Protons; Solvents; Tryptophan | 2001 |
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
Topics: Alanine; Catalysis; Deuterium; Electron Transport; Enzyme Activation; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Protein Conformation; Protons; Serine; Spectrometry, Fluorescence; Temperature; Thermodynamics; Tyrosine; UDPglucose 4-Epimerase | 2001 |
A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase.
Topics: Amino Acid Sequence; Binding Sites; Catalytic Domain; Chromatography, High Pressure Liquid; Deuterium; Diphosphates; Enzyme Inhibitors; Humans; Hypoxanthine Phosphoribosyltransferase; Isoleucine; Leucine; Macromolecular Substances; Magnesium; Magnesium Compounds; Mass Spectrometry; Molecular Sequence Data; Pepsin A; Peptide Fragments; Phenylalanine; Protons; Pyrimidinones; Pyrroles | 2001 |
Glutamine and leucine nitrogen kinetics and their relation to urea nitrogen in newborn infants.
Topics: Blood Urea Nitrogen; Carbon Isotopes; Deuterium; Female; Glutamine; Humans; Infant, Newborn; Infant, Small for Gestational Age; Kinetics; Leucine; Nitrogen; Nitrogen Isotopes; Phenylalanine; Pregnancy; Pregnancy in Diabetics; Urea | 2002 |
Aminoacyl-tRNA enrichment after a flood of labeled phenylalanine: insulin effect on muscle protein synthesis.
Topics: Amino Acids; Animals; Blood Glucose; Deuterium; Dogs; Glucose; Hypoglycemic Agents; Insulin; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Protein Precursors; RNA, Transfer, Amino Acyl | 2002 |
Gas-phase fragmentation of the Ag+-phenylalanine complex: cation-pi interactions and radical cation formation.
Topics: Cations; Deuterium; Free Radicals; Indicators and Reagents; Isotope Labeling; Models, Molecular; Phenylalanine; Silver; Spectrometry, Mass, Electrospray Ionization | 2002 |
Intrinsic deuterium isotope effects on benzylic hydroxylation by tyrosine hydroxylase.
Topics: Deuterium; Hydroxylation; Kinetics; Phenylalanine; Tyrosine 3-Monooxygenase | 2002 |
Use of kinetic isotope effects to delineate the role of phenylalanine 87 in P450(BM-3).
Topics: Amino Acid Substitution; Bacillus megaterium; Bacterial Proteins; Biphenyl Compounds; Catalytic Domain; Cytochrome P-450 Enzyme System; Deuterium; Kinetics; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Phenylalanine; Substrate Specificity; Xylenes | 2002 |
Essential amino acids and muscle protein recovery from resistance exercise.
Topics: Adult; Blood Glucose; Carbon Isotopes; Deuterium; Exercise; Female; Humans; Insulin; Leucine; Male; Muscle, Skeletal; Nitrogen Isotopes; Phenylalanine; Protein Biosynthesis; Urea | 2002 |
Measuring whole-body actin/myosin protein breakdown in mice using a primed constant stable isotope-infusion protocol.
Topics: Actins; Animals; Body Weight; Chromatography, Liquid; Deuterium; Infusions, Intravenous; Lipopolysaccharides; Male; Mass Spectrometry; Methylhistidines; Mice; Mice, Inbred Strains; Models, Animal; Muscles; Myosins; Phenylalanine; Radioactive Tracers; Starvation; Tyrosine | 2003 |
Oxygen and hydrogen isotope effects in an active site tyrosine to phenylalanine mutant of peptidylglycine alpha-hydroxylating monooxygenase: mechanistic implications.
Topics: Amino Acid Substitution; Animals; Binding Sites; Binding, Competitive; Catalysis; Cell Line; Deuterium; Dopamine beta-Hydroxylase; Hippurates; Humans; Hydroxylation; Kinetics; Mixed Function Oxygenases; Multienzyme Complexes; Oxygen Isotopes; Phenylalanine; Tyrosine | 2003 |
No effect of creatine supplementation on human myofibrillar and sarcoplasmic protein synthesis after resistance exercise.
Topics: Adult; Biopsy; Blood Flow Velocity; Carbon Isotopes; Creatine; Deuterium; Diet; Dietary Proteins; Dietary Supplements; Exercise; Humans; Kinetics; Leg; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Myofibrils; Phenylalanine; Polysaccharides; Sarcoplasmic Reticulum | 2003 |
A novel method for the biosynthesis of deuterated proteins with selective protonation at the aromatic rings of Phe, Tyr and Trp.
Topics: Bacterial Proteins; Deuterium; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proteins; Protons; Shikimic Acid; Tryptophan; Tyrosine | 2003 |
Differentiation of natural and synthetic phenylalanine and tyrosine through natural abundance 2H nuclear magnetic resonance.
Topics: Animals; Animals, Genetically Modified; Benzoates; Deuterium; Magnetic Resonance Spectroscopy; Phenylalanine; Phenylethyl Alcohol; Tyrosine | 2003 |
Biosynthesis of yatein in Anthriscus sylvestris.
Topics: 4-Butyrolactone; Apiaceae; Benzyl Compounds; Carbon Isotopes; Deuterium; Dioxoles; Furans; Lactones; Lignans; Mass Spectrometry; Phenylalanine; Podophyllin | 2003 |
Kinetics of gas-phase hydrogen/deuterium exchange and gas-phase structure of protonated phenylalanine, proline, tyrosine and tryptophan.
Topics: Amino Acids; Computer Simulation; Cyclotrons; Deuterium; Deuterium Exchange Measurement; Gases; Hydrogen; Hydrogen Bonding; Kinetics; Models, Molecular; Phase Transition; Phenylalanine; Proline; Protein Conformation; Protons; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Tryptophan; Tyrosine | 2003 |
Solvent and primary deuterium isotope effects show that lactate CH and OH bond cleavages are concerted in Y254F flavocytochrome b2, consistent with a hydride transfer mechanism.
Topics: Catalysis; Deuterium; Deuterium Exchange Measurement; Hydrogen; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrolysis; Hydroxy Acids; Kinetics; L-Lactate Dehydrogenase (Cytochrome); Lactic Acid; Mutagenesis, Site-Directed; Phenylalanine; Saccharomyces cerevisiae Proteins; Solvents; Tyrosine | 2003 |
Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition.
Topics: Amino Acid Sequence; Deuterium; Linear Models; Mass Spectrometry; Peptides; Phenylalanine; Reproducibility of Results; Silicon; Thymopentin; Tyrosine | 2003 |
Supplementation with aromatic amino acids improves leucine kinetics but not aromatic amino acid kinetics in infants with infection, severe malnutrition, and edema.
Topics: Alanine; Amino Acids, Aromatic; Anthropometry; Body Water; Deuterium; Edema; Enteral Nutrition; Humans; Infant; Infections; Intubation, Gastrointestinal; Kinetics; Leucine; Phenylalanine; Protein-Energy Malnutrition; Proteins; Tryptophan; Tyrosine | 2004 |
Determination of phenylalanine isotope ratio enrichment by liquid chromatography/time- of-flight mass spectrometry.
Topics: Animals; Carbon Isotopes; Chromatography, High Pressure Liquid; Deuterium; Isotope Labeling; Phenylalanine; Rabbits; Skin; Spectrometry, Mass, Electrospray Ionization | 2004 |
The mechanism of alpha-proton isotope exchange in amino acids catalysed by tyrosine phenol-lyase. What is the role of quinonoid intermediates?
Topics: Catalysis; Deuterium; Deuterium Exchange Measurement; Escherichia coli; Imines; Kinetics; Methionine; Molecular Structure; Phenylalanine; Protons; Quinones; Tyrosine Phenol-Lyase | 2004 |
A structural study of the myristoylated N-terminus of ARF1.
Topics: ADP-Ribosylation Factor 1; Circular Dichroism; Deuterium; Hydrophobic and Hydrophilic Interactions; Myristic Acid; Phenylalanine; Protein Structure, Secondary | 2005 |
Whole body protein turnover and urea production of preterm small for gestational age infants fed fortified human milk or preterm formula.
Topics: Carbon Isotopes; Deuterium; Dietary Proteins; Food, Fortified; Gas Chromatography-Mass Spectrometry; Humans; Infant Formula; Infant, Newborn; Infant, Premature; Infant, Small for Gestational Age; Milk, Human; Phenylalanine; Urea; Valine | 2005 |
Metabolism of threonine in newborn infants.
Topics: Amino Acids; Carbon; Carbon Dioxide; Carbon Isotopes; Deuterium; Fasting; Glycine; Humans; Infant Formula; Infant, Newborn; Kinetics; L-Serine Dehydratase; Muscle Proteins; Muscle, Skeletal; Nitrogen Isotopes; Oxidation-Reduction; Phenylalanine; Threonine | 2005 |
Phenylalanine side chain behavior of the intestinal fatty acid-binding protein: the effect of urea on backbone and side chain stability.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Deuterium; Diffusion; Dose-Response Relationship, Drug; Fatty Acid-Binding Proteins; Humans; Hydrogen; Magnetic Resonance Spectroscopy; Molecular Conformation; p-Fluorophenylalanine; Phenylalanine; Polyethylene Glycols; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Rats; Urea | 2005 |
Aging is associated with diminished accretion of muscle proteins after the ingestion of a small bolus of essential amino acids.
Topics: Adult; Age Factors; Aged; Aging; Amino Acids, Essential; Area Under Curve; Deuterium; Female; Humans; Infusions, Intravenous; Leg; Male; Muscle Proteins; Phenylalanine; Postprandial Period; Regional Blood Flow | 2005 |
Intrinsic isotope effects on benzylic hydroxylation by the aromatic amino acid hydroxylases: evidence for hydrogen tunneling, coupled motion, and similar reactivities.
Topics: Benzene; Chromatography, High Pressure Liquid; Deuterium; Hydroxylation; Molecular Structure; Phenylalanine; Phenylalanine Hydroxylase; Tyrosine 3-Monooxygenase | 2005 |
Evidence for involvement of the phenylpropanoid pathway in the biosynthesis of the norlignan agatharesinol.
Topics: Carbon Isotopes; Cinnamates; Cryptomeria; Deuterium; Gas Chromatography-Mass Spectrometry; Humidity; Lignans; Phenylalanine | 2006 |
Skeletal muscle protein synthesis after active or passive ascent to high altitude.
Topics: Adult; Alkalosis; Altitude; Deuterium; Environmental Exposure; Female; Follow-Up Studies; Humans; Hydrocortisone; Hypoxia; Insulin-Like Growth Factor I; Male; Methylhistidines; Middle Aged; Mountaineering; Muscle Proteins; Muscle, Skeletal; Nitrogen; Phenylalanine; Thyrotropin; Thyroxine; Triiodothyronine | 2006 |
The organization of aromatic side groups in an amyloid fibril probed by solid-state 2H and 19F NMR spectroscopy.
Topics: Amyloid; Deuterium; Fluorine; Islet Amyloid Polypeptide; Magnetic Resonance Spectroscopy; Molecular Structure; Peptide Fragments; Phenylalanine; Protein Structure, Secondary | 2006 |
Insights into the catalytic mechanisms of phenylalanine and tryptophan hydroxylase from kinetic isotope effects on aromatic hydroxylation.
Topics: Animals; Binding Sites; Catalysis; Deuterium; Hydroxylation; Isotopes; Kinetics; Mutation; Oxidation-Reduction; Phenylalanine; Phenylalanine Hydroxylase; Pterins; Rats; Tryptophan; Tryptophan Hydroxylase; Tyrosine 3-Monooxygenase | 2006 |
NMR resonance assignments for sparsely 15N labeled proteins.
Topics: Amides; Amino Acid Sequence; Deuterium; Galectin 3; Molecular Sequence Data; Nitrogen; Nitrogen Isotopes; Nuclear Magnetic Resonance, Biomolecular; Peptides; Phenylalanine; Protein Folding; Protein Structure, Tertiary; Protons | 2007 |
Quantitation of phenylalanine and its trans-cinnamic, benzoic and hippuric acid metabolites in biological fluids in a single GC-MS analysis.
Topics: Animals; Benzoic Acid; Cinnamates; Deuterium; Drug Therapy, Combination; Gas Chromatography-Mass Spectrometry; Hippurates; Mice; Mice, Mutant Strains; Phenylalanine; Phenylalanine Ammonia-Lyase | 2007 |
Enhanced stability of cis Pro-Pro peptide bond in Pro-Pro-Phe sequence motif.
Topics: Amino Acid Sequence; Deuterium; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Oligopeptides; Phenylalanine; Proline; Protein Binding; Stereoisomerism | 2007 |
Amino acid metabolism and inflammatory burden in ovarian cancer patients undergoing intense oncological therapy.
Topics: Amino Acids; Blood Chemical Analysis; Cytokines; Deuterium; Female; Humans; Inflammation; Middle Aged; Muscle Proteins; NF-kappa B; Ovarian Neoplasms; Phenylalanine | 2007 |
Synthesis of isotopically labeled P-site substrates for the ribosomal peptidyl transferase reaction.
Topics: Carbon Isotopes; Deuterium; Isotope Labeling; Kinetics; Molecular Conformation; Nitrogen Isotopes; Oligonucleotides; Oxygen Isotopes; Peptides; Peptidyl Transferases; Phenylalanine; Ribosomes; Stereoisomerism | 2008 |
Phenylalanine and tyrosine kinetics in compensated liver cirrhosis: effects of meal ingestion.
Topics: Adult; Case-Control Studies; Deuterium; Eating; Fasting; Humans; Hydroxylation; Infusions, Intravenous; Kinetics; Liver Cirrhosis; Male; Middle Aged; Phenylalanine; Protein Biosynthesis; Severity of Illness Index; Tyrosine; Up-Regulation | 2008 |
Evidence for protein radical-mediated nuclear tunneling in fatty acid alpha-oxygenase.
Topics: Carbon; Catalysis; Deuterium; Fatty Acids; Free Radicals; Hydrogen; Kinetics; Oryza; Oxidation-Reduction; Oxygen; Oxygenases; Phenylalanine; Proteins; Spectrum Analysis; Thermodynamics; Tyrosine | 2008 |
Fractional protein synthesis rates are similar when measured by intraperitoneal or intravenous flooding doses of L-[ring-2H5]phenylalanine in combination with a rapid regimen of sampling in piglets.
Topics: Animals; Body Weight; Deuterium; Female; Injections, Intraperitoneal; Injections, Intravenous; Isotope Labeling; Kinetics; Organ Specificity; Phenylalanine; Proteins; Swine | 2008 |
Noninvasive imaging of protein metabolic labeling in single human cells using stable isotopes and Raman microscopy.
Topics: Deuterium; HeLa Cells; Humans; Methionine; Phenylalanine; Proteins; Spectrum Analysis, Raman; Tyrosine | 2008 |
Feeding acutely stimulates fibrinogen synthesis in healthy young and elderly adults.
Topics: Acute-Phase Proteins; Adult; Aged; Deuterium; Dietary Carbohydrates; Dietary Proteins; Eating; Female; Fibrinogen; Humans; Interleukin-6; Intestinal Absorption; Male; Middle Aged; Phenylalanine; Reference Values; Young Adult | 2009 |
The production of intrinsically labeled milk protein provides a functional tool for human nutrition research.
Topics: Absorption; Animals; Carbon Isotopes; Cattle; Deuterium; Dietary Proteins; Digestion; Female; Humans; Isotope Labeling; Leucine; Male; Middle Aged; Milk; Milk Proteins; Muscle Proteins; Nutritional Physiological Phenomena; Phenylalanine; Research; Tyrosine | 2009 |
Improved measurement of protein synthesis in human subjects using 2H-phenylalanine isotopomers and gas chromatography/mass spectrometry.
Topics: Albumins; Amino Acids; Deuterium; Esters; Fluorocarbons; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Organosilicon Compounds; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins | 2010 |
Glucosylthioureidocalix[4]arenes: Synthesis, conformations and gas phase recognition of amino acids.
Topics: Amino Acids; Deuterium; Gases; Hydrogen; Hydrogen Bonding; Leucine; Magnetic Resonance Spectroscopy; Molecular Conformation; Phenylalanine; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Tryptophan; Tyrosine | 2010 |
Regulation of phenylalanine hydroxylase: conformational changes upon phenylalanine binding detected by hydrogen/deuterium exchange and mass spectrometry.
Topics: Amino Acid Sequence; Animals; Binding Sites; Catalytic Domain; Deuterium; Hydrogen; Kinetics; Mass Spectrometry; Models, Molecular; Molecular Sequence Data; Phenylalanine; Phenylalanine Hydroxylase; Protein Conformation; Rats | 2010 |
Slow motions in the hydrophobic core of chicken villin headpiece subdomain and their contributions to configurational entropy and heat capacity from solid-state deuteron NMR measurements.
Topics: Animals; Chickens; Deuterium; Entropy; Hydrophobic and Hydrophilic Interactions; Microfilament Proteins; Models, Molecular; Mutation; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Solvents | 2011 |
Biosynthesis and cellular localization of functional polyketides in the gastropod mollusc Scaphander lignarius.
Topics: Animals; Aquatic Organisms; Benzoic Acid; Carbon Isotopes; Cinnamates; Cytoplasm; Deuterium; Eukaryotic Cells; Gastropoda; Magnetic Resonance Spectroscopy; Phenylalanine; Phenylalanine Ammonia-Lyase; Polyenes; Polyketides; Propionates | 2012 |
2H-13C HETCOR MAS NMR for indirect detection of 2H quadrupole patterns and spin-lattice relaxation rates.
Topics: Alanine; Algorithms; Deuterium; Electromagnetic Fields; Isotope Labeling; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proline | 2013 |
Determination of very low stable isotope enrichments of [(2)H(5)]-phenylalanine in chicken liver using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Topics: Analysis of Variance; Animals; Chickens; Chromatography, High Pressure Liquid; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Linear Models; Liver; Phenylalanine; Reproducibility of Results; Tandem Mass Spectrometry | 2012 |
Disuse impairs the muscle protein synthetic response to protein ingestion in healthy men.
Topics: Adult; Casts, Surgical; Deuterium; Dietary Proteins; Down-Regulation; Humans; Kinetics; Leg; Male; Muscle Proteins; Muscle Strength; Muscular Atrophy; Phenylalanine; Phosphorylation; Postprandial Period; Protein Processing, Post-Translational; Quadriceps Muscle; Restraint, Physical; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Young Adult | 2013 |
Comparison of bolus injection and constant infusion methods for measuring muscle protein fractional synthesis rate in humans.
Topics: Aged; Deuterium; Female; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Middle Aged; Muscle Proteins; Phenylalanine; Radiopharmaceuticals | 2014 |
A rapid and convenient method for measuring the fractional rate of protein synthesis in ectothermic animal tissues using a stable isotope tracer.
Topics: Animals; Deuterium; Gas Chromatography-Mass Spectrometry; Isotopes; Liver; Muscle Proteins; Phenylalanine; Protein Biosynthesis; Trout | 2015 |
Interaction of L-Phenylalanine with a Phospholipid Monolayer at the Water-Air Interface.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Air; Deuterium; Microscopy; Molecular Dynamics Simulation; Molecular Structure; Phenylalanine; Surface Properties; Water | 2015 |
Dosimetry determines the initial OH radical concentration in fast photochemical oxidation of proteins (FPOP).
Topics: Deuterium; Free Radical Scavengers; Gas Chromatography-Mass Spectrometry; Glutamine; Histidine; Hydrogen Peroxide; Hydroxyl Radical; Indicator Dilution Techniques; Kinetics; Lasers; Methionine; Models, Molecular; Osmolar Concentration; Oxidants; Oxidation-Reduction; Phenylalanine; Photolysis; Proteins; Radiation Dosage | 2015 |
Indian women of childbearing age do not metabolically conserve arginine as do American and Jamaican women.
Topics: Adult; Arginine; Body Composition; Carbon Isotopes; Citrulline; Deuterium; Energy Metabolism; Female; Humans; India; Indicator Dilution Techniques; Jamaica; Meals; Models, Biological; Nitrogen Isotopes; Nutritional Requirements; Ornithine; Phenylalanine; Texas | 2015 |
Presleep protein ingestion does not compromise the muscle protein synthetic response to protein ingested the following morning.
Topics: Adult; Carbon Isotopes; Deuterium; Dietary Carbohydrates; Dietary Proteins; Exercise; Healthy Volunteers; Humans; Leucine; Male; Muscle Proteins; Muscle, Skeletal; Phenylalanine; Protein Biosynthesis; Resistance Training; Sleep; Young Adult | 2016 |
Allelopathic effects of exogenous phenylalanine: a comparison of four monocot species.
Topics: Allelopathy; Araceae; Biomass; Deuterium; Germination; Glucose; Hydroponics; Lolium; Panicum; Phenylalanine; Plant Leaves; Plant Roots; Plant Stems; Secale | 2017 |
Genetically encoded amino acids with tert-butyl and trimethylsilyl groups for site-selective studies of proteins by NMR spectroscopy.
Topics: Amino Acids; Deuterium; Molecular Weight; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Proteins; Proton Magnetic Resonance Spectroscopy; Time Factors | 2018 |
Synthesis of stable isotope-labeled nasturlexins and potential precursors to probe biosynthetic pathways of cruciferous phytoalexins.
Topics: Deuterium; Glucosinolates; Nitrobenzenes; Phenylalanine; Phytoalexins; Sesquiterpenes; Thiocarbamates; Thiocyanates | 2018 |
A novel triple-tracer approach to assess postprandial protein turnover.
Topics: Carbon Isotopes; Deuterium; Fasting; Female; Healthy Volunteers; Humans; Male; Nitrogen Isotopes; Phenylalanine; Postprandial Period; Proteins; Proteostasis; Young Adult | 2018 |
Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation.
Topics: 3-Deoxy-7-Phosphoheptulonate Synthase; Binding Sites; Catalysis; Communication; Crystallography, X-Ray; Deuterium; Escherichia coli; Humans; Isoenzymes; Ligands; Phenylalanine; Phosphates | 2022 |
Enzymatic synthesis of halogen derivatives of L-phenylalanine and phenylpyruvic acid stereoselectively labeled with hydrogen isotopes in the side chain.
Topics: Deuterium; Halogens; Hydrogen; Phenylalanine; Phenylpyruvic Acids; Tritium | 2023 |
Heavy Water Reduces the Electronic Conductance of Protein Wires via Deuteron Interactions with Aromatic Residues.
Topics: Deuterium; Deuterium Oxide; Phenylalanine; Proteins; Protons; Solvents; Tryptophan | 2023 |