Compounds > phenylalanine

phenylalanine and dermorphin

phenylalanine has been researched along with dermorphin in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's4 (44.44)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Golbraikh, AA; Nikiforovich, GV; Shenderovich, MD1
Lemieux, C; Maziak, LA; Nguyen, TM; Schiller, PW; Wilkes, BC1
Davis, P; Frycia, A; Hruby, VJ; Jaspers, H; Porreca, F; Toth, G; Tourwé, D; Van Binst, G; Verheyden, P; Verschueren, K1
Abe, H; Kimura, H; Renda, TG; Tooyama, I1
Ambo, A; Murase, H; Niizuma, H; Ouchi, H; Sasaki, Y; Yamamoto, Y1
Aldrich, JV; Choi, H; Murray, TF1
Ambo, A; Kohara, H; Niizuma, H; Sasaki, A; Sasaki, Y1
Ballet, S; De Wachter, R; Hendrickx, PM; Keresztes, A; Mallareddy, JR; Martins, JC; Tóth, F; Tóth, G; Tourwé, D; Vandormael, B1
Ejchart, A; Frączak, O; Kosson, P; Lasota, A; Maciejczyk, M; Misicka, A; Nowakowski, M; Olma, A1

Other Studies

9 other study(ies) available for phenylalanine and dermorphin

ArticleYear
Conformational features responsible for the binding of cyclic analogues of enkephalin to opioid receptors. III. Probable binding conformations of mu-agonists with phenylalanine in position 3.
    International journal of peptide and protein research, 1991, Volume: 37, Issue:4

    Topics: Amino Acid Sequence; Endorphins; Enkephalins; Molecular Sequence Data; Molecular Structure; Oligopeptides; Opioid Peptides; Phenylalanine; Protein Conformation; Receptors, Opioid; Receptors, Opioid, mu; Structure-Activity Relationship

1991
Structure-activity relationships of cyclic opioid peptide analogues containing a phenylalanine residue in the 3-position.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:11

    Topics: Animals; Endorphins; Guinea Pigs; Mice; Oligopeptides; Opioid Peptides; Phenylalanine; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship

1987
Conformational restriction of Tyr and Phe side chains in opioid peptides: information about preferred and bioactive side-chain topology.
    Biopolymers, 1996, Volume: 38, Issue:1

    Topics: Amino Acid Sequence; Analgesics, Opioid; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Structure; Oligopeptides; Opioid Peptides; Phenylalanine; Protein Binding; Protein Conformation; Receptors, Opioid; Stereoisomerism; Tyrosine

1996
Production and immunohistochemical application of antiserum against Tyr-D-Ala-Phe, a N-terminal tripeptide common to dermorphin/deltorphin family.
    Peptides, 2000, Volume: 21, Issue:11

    Topics: Alanine; Animals; Chromatography, Affinity; Immune Sera; Immunoglobulin G; Immunohistochemistry; Magnetic Resonance Spectroscopy; Oligopeptides; Opioid Peptides; Peptide Biosynthesis; Peptides; Phenylalanine; Polylysine; Protein Binding; Rabbits; Ranidae; Skin; Tyrosine

2000
Dermorphin and deltorphin heptapeptide analogues: replacement of Phe residue by Dmp greatly improves opioid receptor affinity and selectivity.
    Bioorganic & medicinal chemistry letters, 2002, Mar-25, Volume: 12, Issue:6

    Topics: Analgesics, Opioid; Animals; Guinea Pigs; Inhibitory Concentration 50; Muscle Contraction; Muscle, Smooth; Narcotic Antagonists; Oligopeptides; Opioid Peptides; Phenylalanine; Protein Binding; Receptors, Opioid; Structure-Activity Relationship

2002
Dermorphin-based potential affinity labels for mu-opioid receptors.
    The journal of peptide research : official journal of the American Peptide Society, 2003, Volume: 61, Issue:1

    Topics: Affinity Labels; Amino Acid Sequence; Animals; Binding, Competitive; CHO Cells; Cricetinae; Female; Inhibitory Concentration 50; Isothiocyanates; Ligands; Oligopeptides; Opioid Peptides; Phenylalanine; Radioligand Assay; Receptors, Opioid, delta; Receptors, Opioid, mu

2003
Dermorphin tetrapeptide analogues with 2',6'-dimethylphenylalanine (Dmp) substituted for aromatic amino acids have high mu opioid receptor binding and biological activities.
    Bioorganic & medicinal chemistry letters, 2003, Apr-07, Volume: 13, Issue:7

    Topics: Amino Acids, Aromatic; Analgesics, Opioid; Animals; Dose-Response Relationship, Drug; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Kinetics; Male; Mice; Muscle Contraction; Muscle, Smooth; Oligopeptides; Opioid Peptides; Pain Measurement; Phenylalanine; Receptors, Opioid, mu; Vas Deferens

2003
Asymmetric synthesis and conformational analysis by NMR spectroscopy and MD of Aba- and α-MeAba-containing dermorphin analogues.
    ChemMedChem, 2011, Nov-04, Volume: 6, Issue:11

    Topics: Animals; Benzazepines; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Methylation; Molecular Dynamics Simulation; Opioid Peptides; Peptides; Phenylalanine; Protein Conformation; Rats; Receptors, Opioid, delta; Receptors, Opioid, mu; Stereoisomerism; Structure-Activity Relationship

2011
The impact of β-azido(or 1-piperidinyl)methylamino acids in position 2 or 3 on biological activity and conformation of dermorphin analogues.
    Journal of peptide science : an official publication of the European Peptide Society, 2016, Volume: 22, Issue:8

    Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Analgesics, Opioid; Animals; Azides; Binding Sites; Binding, Competitive; Brain Chemistry; Cell Membrane; Drug Design; Ligands; Molecular Dynamics Simulation; Opioid Peptides; Phenylalanine; Piperidines; Protein Binding; Protein Structure, Secondary; Rats; Rats, Wistar; Receptors, Opioid, delta; Receptors, Opioid, mu; Structure-Activity Relationship

2016