phenylalanine has been researched along with cyclosporine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 3 (17.65) | 2.80 |
| Authors | Studies |
|---|---|
| Avdeef, A; Tam, KY | 1 |
| Dreslin, JA; Grizzuti, K; Gros, P; Kajiji, S | 1 |
| Chen, KG; Cohen, D; Durán, GE; Lacayo, NJ; Sikic, BI | 1 |
| Matsuo, H; Morimoto, S; Ohnishi, A; Ohtani, H; Sawada, Y; Shoyama, Y; Takanaga, H; Yamada, S | 1 |
| Bianchi, E; Cristallo, M; Di Carlo, V; Dodesini, R; Luzi, L; Pastore, MR; Piceni Sereni, L; Pozza, G; Secchi, A; Spessot, M; Terruzzi, I | 1 |
| Bartlett, MC; Clarke, DM; Loo, TW | 1 |
| Iwamura, H; Sato, M; Wakitani, K | 1 |
| Baillie, TA; Bleasby, K; Chen, Q; Colletti, A; Dean, DC; Evers, R; Hafey, M; Hagmann, WK; Lanza, TJ; Lin, LS; Magriotis, PA; Stearns, RA; Tang, W; Teffera, Y | 1 |
| Kwatra, D; Luo, S; Mitra, AK; Pal, D; Paturi, KD; Shah, SJ | 1 |
| Izumi, S; Komori, T; Kusuhara, H; Maeda, K; Nozaki, Y; Sugiyama, Y; Takenaka, O | 1 |
| Bonifacio, L; Covington, P; Davenport, JM; McIntyre, G; Venitz, J | 1 |
| Asbell, PA; Kuklinski, E | 1 |
| Kang, S; Kim, CE; Kim, K; Kleinman, HK; Ousler, GW; Sosne, G; Yang, J | 1 |
| Akpek, EK; Amescua, G; Dunn, SP; Farid, M; Garcia-Ferrer, FJ; Lin, A; Mah, FS; Musch, DC; Rhee, MK; Varu, DM | 1 |
| Lin, MC; Neri, P; Perez, VL; Periman, LM; Saban, DR | 1 |
| Evans, DG; Karpecki, PM; Nichols, KK | 1 |
| Abbas, AA; Afshari, NA; Bahar, I; Bu, JJ; Cohen-Tayar, Y; Finburgh, EN; Hakim, DF; Lian, RR; Noguchi, T; Sella, R; Shaw, P; Zhao, J | 1 |
4 review(s) available for phenylalanine and cyclosporine
| Article | Year |
|---|---|
Sjogren's syndrome from the perspective of ophthalmology.
Topics: Administration, Ophthalmic; Cyclosporine; Dry Eye Syndromes; Fatty Acids, Omega-3; Glucocorticoids; Humans; Immunosuppressive Agents; Lubricant Eye Drops; Muscarinic Agonists; Ophthalmology; Phenylalanine; Pilocarpine; Punctal Plugs; Quinuclidines; Sjogren's Syndrome; Sulfones; Thiophenes | 2017 |
Dry Eye Syndrome Preferred Practice Pattern®.
Topics: Academies and Institutes; Cyclosporine; Diagnostic Techniques, Ophthalmological; Dry Eye Syndromes; Humans; Immunosuppressive Agents; Ophthalmic Solutions; Ophthalmology; Phenylalanine; Physical Examination; Practice Patterns, Physicians'; Sulfones; United States | 2019 |
The Immunological Basis of Dry Eye Disease and Current Topical Treatment Options.
Topics: Administration, Topical; Clinical Decision-Making; Cyclosporine; Dry Eye Syndromes; Goblet Cells; Homeostasis; Humans; Immunologic Factors; Immunosuppressive Agents; Inflammation; Integrins; Intercellular Adhesion Molecule-1; Lacrimal Apparatus; Lymphocyte Function-Associated Antigen-1; Phenylalanine; Steroids; Sulfones; T-Lymphocytes; Tears | 2020 |
A Comprehensive Review of the Clinical Trials Conducted for Dry Eye Disease and the Impact of the Vehicle Comparators in These Trials.
Topics: Administration, Ophthalmic; Clinical Trials as Topic; Cyclosporine; Dry Eye Syndromes; Emulsions; Humans; Ophthalmic Solutions; Pharmaceutical Vehicles; Phenylalanine; Sulfones | 2021 |
1 trial(s) available for phenylalanine and cyclosporine
| Article | Year |
|---|---|
Effect of uptake transporters OAT3 and OATP1B1 and efflux transporter MRP2 on the pharmacokinetics of eluxadoline.
Topics: Adult; Area Under Curve; Cross-Over Studies; Cyclosporine; Half-Life; Humans; Imidazoles; Liver-Specific Organic Anion Transporter 1; Metabolic Clearance Rate; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Phenylalanine; Probenecid | 2015 |
12 other study(ies) available for phenylalanine and cyclosporine
| Article | Year |
|---|---|
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Structurally distinct MDR modulators show specific patterns of reversal against P-glycoproteins bearing unique mutations at serine939/941.
Topics: Amino Acid Sequence; Animals; Cell Survival; CHO Cells; Clone Cells; Cricetinae; Cyclosporine; Dibenzocycloheptenes; Drug Resistance; Glycoproteins; Isoquinolines; Mice; Phenylalanine; Point Mutation; Quinazolines; Quinolines; Recombinant Proteins; Serine; Transfection; Vinblastine | 1994 |
Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted phe(335).
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Calcium Channel Blockers; Cyclosporine; Dihydropyridines; Drug Interactions; Enzyme Activation; Humans; Molecular Sequence Data; Phenylalanine; Photoaffinity Labels; Tritium; Tumor Cells, Cultured; Vanadates; Verapamil | 2000 |
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.
Topics: 3-O-Methylglucose; 5-Methoxypsoralen; Acetates; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Carbon Radioisotopes; Cell Line; Cell Line, Transformed; Citrus; Coumarins; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Furocoumarins; Humans; Hydroxylation; Magnetic Resonance Spectroscopy; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; Phenylalanine; Plant Extracts; Recombinant Proteins; Testosterone; Tritium; Vinblastine | 2000 |
Postabsorptive muscle protein metabolism in type 1 diabetic patients after pancreas transplantation.
Topics: Adult; Blood Glucose; C-Peptide; Cyclosporine; Diabetes Mellitus, Type 1; Energy Intake; Forearm; Glycated Hemoglobin; Humans; Immunosuppressive Agents; Insulin; Leucine; Middle Aged; Muscle Proteins; Muscle, Skeletal; Pancreas Transplantation; Phenylalanine; Prednisone; Protein Biosynthesis; Proteins; Reference Values; Regional Blood Flow | 2000 |
Processing mutations located throughout the human multidrug resistance P-glycoprotein disrupt interactions between the nucleotide binding domains.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Cross-Linking Reagents; Cyclosporine; Cytoplasm; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Gene Deletion; Humans; Immunoblotting; Models, Biological; Mutation; Phenylalanine; Protein Binding; Protein Folding; Protein Structure, Tertiary | 2004 |
Comparative study of glucocorticoids, cyclosporine A, and JTE-607 [(-)-Ethyl-N[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]-L-phenylalaninate dihydrochloride] in a mouse septic shock model.
Topics: Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cyclosporine; Cytokines; Enzyme-Linked Immunosorbent Assay; Glucocorticoids; Immunosuppressive Agents; Leukocyte Count; Lung; Male; Mice; Mice, Inbred BALB C; Peroxidase; Phenylalanine; Piperazines; Platelet Count; Prednisolone; Shock, Septic | 2004 |
Importance of mechanistic drug metabolism studies in support of drug discovery: A case study with an N -sulfonylated dipeptide VLA-4 antagonist in rats.
Topics: Animals; Cells, Cultured; Cyclosporine; Dogs; Inactivation, Metabolic; Integrin alpha4beta1; Microsomes, Liver; Organic Anion Transporters, Sodium-Independent; Phenylalanine; Rats; Rats, Sprague-Dawley; Solute Carrier Organic Anion Transporter Family Member 1B3; Time Factors; Triazoles | 2008 |
Effect of HEPES buffer on the uptake and transport of P-glycoprotein substrates and large neutral amino acids.
Topics: Adenosine Triphosphate; Amino Acids, Neutral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line; Cell Membrane Permeability; Cyclosporine; Dogs; Glutamic Acid; HEPES; Humans; Lopinavir; Phenylalanine; Pyrimidinones; Ritonavir; Verapamil | 2010 |
Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions.
Topics: Antihypertensive Agents; Binding, Competitive; Biological Transport; Cyclohexanes; Cyclosporine; Drug Evaluation, Preclinical; Drug Interactions; Estradiol; Gemfibrozil; HEK293 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Kinetics; Liver-Specific Organic Anion Transporter 1; Membrane Transport Modulators; Models, Biological; Nateglinide; Organic Anion Transporters; Phenylalanine; Recombinant Proteins; Rifampin; Sulfonamides; Torsemide | 2015 |
RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model.
Topics: Animals; Conjunctiva; Cornea; Cyclosporine; Disease Models, Animal; Dry Eye Syndromes; Female; Goblet Cells; Humans; Inflammation Mediators; Lacrimal Apparatus; Male; Mice; Mice, Inbred NOD; Mucins; Ophthalmic Solutions; Phenylalanine; Polyphosphates; Prescription Drugs; Scopolamine; Sulfones; Tears; Thymosin; Treatment Outcome; Uracil Nucleotides | 2018 |
The Effect of Anti-Inflammatory Topical Ophthalmic Treatments on In Vitro Corneal Epithelial Cells.
Topics: Anti-Inflammatory Agents; Cyclosporine; Epithelial Cells; Humans; Ophthalmic Solutions; Phenylalanine; Sulfones; Tacrolimus | 2022 |