phenylalanine and atrial natriuretic factor

phenylalanine has been researched along with atrial natriuretic factor in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.41)18.7374
1990's11 (40.74)18.2507
2000's12 (44.44)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Léan, A; Escher, E; McNicoll, N; Ong, H; Schiller, PW; Wilkes, BC1
Carvalho, KM; Christophe, J; Cohen, P; Delporte, C; Leseney, AM; Winand, J1
Casley, DJ; Haslanger, MF; Johnston, CI; Kanazawa, M; Sybertz, EJ1
Deschodt-Lanckman, M; Michel, A; Vanneste, Y1
Furuya, M; Kitajima, Y; Minamitake, Y; Tanaka, S; Yoshida, M1
Durley, RC; Krieter, PA; Olins, GM; Verrett, SP1
Craven, TG; Kem, DC; Schiebinger, RJ1
Chiesi, M; Grueninger, S; Lesniak, W; Schaefer, C1
De Lombaert, S; Ghai, RD; Jeng, AY; Trapani, AJ; Webb, RL1
Hänze, J; Jarygin, C; Lang, RE1
Abe, K; Kanazawa, M; Kohzuki, M; Yasujima, M1
Allard, MF; Bondy, GP; Levin, A; McManus, BM; Thompson, CR; Yu, JZ1
Casley, DJ; Johnston, CI; Kanazawa, M; Katopothis, A; Yoshida, K1
Flesch, M; Frischkopf, K; Piper, HM; Rosenkranz, S; Schlüter, KD; Taimor, G1
Bani, M; Colantoni, A; Guillaume, M; Macchi, F; Moroni, G; Persiani, S1
Deng, XF; Rokosh, DG; Simpson, PC1
Horio, T; Kangawa, K; Matsuo, H; Matsuoka, H; Miyata, A; Nagaya, N; Nishikimi, T; Takishita, S; Yoshihara, F; Yutani, C1
Nagai, R; Yamazaki, T; Zou, Y1
Beil, ME; Bruseo, CW; Fink, CA; Hoyer, D; Jeng, AY; Savage, P; Trapani, AJ2
Akimoto, K; Asakawa, H; Horio, T; Matsuoka, H; Minamino, N; Mori, Y; Nishikimi, T; Tadokoro, K; Wang, X; Yoshihara, F1
Dusting, GJ; Hood, SG; Ritchie, RH; Rosenkranz, AC; Woods, RL1
Adiarto, S; Emoto, N; Isaka, D; Jeng, AY; Masuda, S; Raharjo, SB; Yokoyama, M1
Arsenault, D; Battistini, B; Beaudoin, M; Belleville, K; Benrezzak, O; Blouin, A; Cayer, J; Daull, P; Jeng, AY; Nantel, F; Pheng, LH; Sirois, P1
Dukkipati, A; Garcia, KC; He, XL1
Miličević, A; Raos, N1
Cheng, ML; Liu, MH; Wang, CH1

Trials

1 trial(s) available for phenylalanine and atrial natriuretic factor

ArticleYear
A double-blind, placebo-controlled study to assess tolerability, pharmacokinetics and preliminary pharmacodynamics of single escalating doses of Z13752A, a novel dual inhibitor of the metalloproteases ACE and NEP, in healthy volunteers.
    British journal of clinical pharmacology, 2000, Volume: 50, Issue:4

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Cyclic GMP; Double-Blind Method; Humans; Male; Metalloendopeptidases; Neprilysin; Peptidyl-Dipeptidase A; Phenylalanine; Protease Inhibitors; Urination

2000

Other Studies

26 other study(ies) available for phenylalanine and atrial natriuretic factor

ArticleYear
Highly efficient photoaffinity labeling of the hormone binding domain of atrial natriuretic factor receptor.
    Biochemistry, 1992, May-12, Volume: 31, Issue:18

    Topics: Affinity Labels; Aldosterone; Amino Acid Sequence; Animals; Atrial Natriuretic Factor; Cattle; Models, Molecular; Molecular Sequence Data; Peptides; Phenylalanine; Photochemistry; Protein Binding; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface

1992
A new metallo- endopeptidase from human neuroblastoma NB-OK-1 cells which inactivates atrial natriuretic peptide by selective cleavage at the Ser123-Phe124 bond.
    Biochemical and biophysical research communications, 1992, Jan-15, Volume: 182, Issue:1

    Topics: Amino Acid Sequence; Animals; Atrial Natriuretic Factor; Cell Line; Humans; Kinetics; Metalloendopeptidases; Molecular Sequence Data; Neuroblastoma; Neuropeptides; Oligopeptides; Peptide Fragments; Phenylalanine; Protease Inhibitors; Sequence Homology, Nucleic Acid; Serine; Xenopus laevis

1992
Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor.
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Autoradiography; Binding, Competitive; Cell Membrane; Dipeptides; Drug Interactions; Glycopeptides; Iodine Radioisotopes; Kidney; Male; Neprilysin; Phenols; Phenylalanine; Rats; Rats, Inbred Strains; Thiorphan

1992
Hydrolysis of intact and Cys-Phe-cleaved human atrial natriuretic peptide in vitro by human tissue kallikrein.
    European journal of biochemistry, 1991, Mar-14, Volume: 196, Issue:2

    Topics: Amino Acid Sequence; Atrial Natriuretic Factor; Chromatography, High Pressure Liquid; Cysteine; Humans; Hydrolysis; Kallikreins; Kinetics; Molecular Sequence Data; Peptide Fragments; Peptide Mapping; Phenylalanine; Structure-Activity Relationship; Substrate Specificity

1991
Importance of hydrophobic residues in alpha-human atrial natriuretic peptide (alpha-hANP) for vasorelaxant activity.
    Biochemical and biophysical research communications, 1990, Nov-15, Volume: 172, Issue:3

    Topics: Amino Acid Sequence; Animals; Aorta; Atrial Natriuretic Factor; Cells, Cultured; Humans; Methionine; Molecular Sequence Data; Peptide Fragments; Phenylalanine; Rats; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Solubility; Vasodilation

1990
In vivo metabolism of atrial natriuretic peptide: identification of plasma metabolites and enzymes responsible for their generation.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Carboxypeptidases; Endopeptidases; Kidney; Phenylalanine; Rats; Thiorphan; Tyrosine

1989
Atrial natriuretic peptides: the role of phenylalanine on biological activity.
    Endocrinology, 1988, Volume: 122, Issue:3

    Topics: Adrenal Glands; Alanine; Aldosterone; Animals; Atrial Natriuretic Factor; Female; Peptide Fragments; Phenylalanine; Potassium; Rats; Rats, Inbred Strains; Structure-Activity Relationship

1988
Effect of alpha adrenergic stimulation and carnitine palmitoyl transferase I inhibition on hypertrophying adult rat cardiomyocytes in culture.
    Molecular and cellular biochemistry, 1995, Jan-12, Volume: 142, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Base Sequence; Cardiomegaly; Cell Division; Cells, Cultured; DNA; Epoxy Compounds; Gene Expression; Glucose; Molecular Sequence Data; Myocardium; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Phenylalanine; Phenylephrine; Protein Biosynthesis; Rats; Sodium Channels

1995
Pharmacological profile of a non-peptidic dual inhibitor of neutral endopeptidase 24.11 and endothelin-converting enzyme.
    Biochemical and biophysical research communications, 1994, Oct-14, Volume: 204, Issue:1

    Topics: Amino Acid Sequence; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; Cell Membrane; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Kidney Cortex; Kinetics; Male; Metalloendopeptidases; Molecular Sequence Data; Neprilysin; Oligopeptides; Organophosphonates; Phenylalanine; Protein Precursors; Rats; Rats, Inbred SHR; Substrate Specificity; Tetrazoles

1994
Gene expression of atrial natriuretic peptide in rat papillary muscle. Rapid induction by mechanical loading.
    FEBS letters, 1994, Jun-13, Volume: 346, Issue:2-3

    Topics: Animals; Atrial Natriuretic Factor; Blotting, Northern; Gene Expression; Male; Mechanoreceptors; Papillary Muscles; Phenylalanine; Rats; Rats, Wistar; RNA, Messenger

1994
[Activity and localization of neutral metalloendopeptidase (EC 3.4.24.11) (NEP), the degradative enzyme for atrial natriuretic peptide (ANP), in rat kidney].
    Nihon Jinzo Gakkai shi, 1994, Volume: 36, Issue:7

    Topics: Animals; Atrial Natriuretic Factor; Autoradiography; Kidney; Male; Neprilysin; Phenols; Phenylalanine; Rats; Rats, Sprague-Dawley

1994
Serum from patients with chronic renal insufficiency alters growth characteristics and ANP mRNA expression of adult rat cardiac myocytes.
    Journal of molecular and cellular cardiology, 1996, Volume: 28, Issue:12

    Topics: Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; Gene Expression; Growth Substances; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Male; Myocardium; Phenylalanine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thymidine; Tritium

1996
Inhibition of kidney neutral endopeptidase after administration of the neutral endopeptidase inhibitor candoxatril: quantitation by autoradiography.
    Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:5

    Topics: Animals; Atrial Natriuretic Factor; Autoradiography; Indans; Kidney; Male; Neprilysin; Phenols; Phenylalanine; Propionates; Protease Inhibitors; Rats; Rats, Sprague-Dawley

1998
Central role for ornithine decarboxylase in beta-adrenoceptor mediated hypertrophy.
    Cardiovascular research, 2000, Jan-14, Volume: 45, Issue:2

    Topics: Adrenergic beta-Agonists; Analysis of Variance; Animals; Animals, Genetically Modified; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Enzyme Activation; Isoproterenol; Male; Myocardium; Ornithine Decarboxylase; Perfusion; Phenylalanine; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Transforming Growth Factor beta

2000
Autonomous and growth factor-induced hypertrophy in cultured neonatal mouse cardiac myocytes. Comparison with rat.
    Circulation research, 2000, Oct-27, Volume: 87, Issue:9

    Topics: Adrenergic alpha-Agonists; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cells, Cultured; Dinoprost; Endothelin-1; Fetus; Growth Inhibitors; Growth Substances; Heart; Hypertrophy; Interleukin-1; Interleukin-6; Leukemia Inhibitory Factor; Lymphokines; Mice; Microscopy, Phase-Contrast; Models, Animal; Myocardium; Myosin Heavy Chains; Myosins; Norepinephrine; Phenotype; Phenylalanine; Protein Biosynthesis; Proteins; Rats; RNA, Messenger; Tetradecanoylphorbol Acetate; Triiodothyronine

2000
Urocortin, a member of the corticotropin-releasing factor family, in normal and diseased heart.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:6

    Topics: Animals; Atrial Natriuretic Factor; Carbon Radioisotopes; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Gene Expression; Heart Failure; Hormone Antagonists; Hypertrophy, Left Ventricular; Immunohistochemistry; Muscle Fibers, Skeletal; Myocardium; Peptide Fragments; Phenylalanine; Proline; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Corticotropin-Releasing Hormone; RNA, Messenger; Thymidine; Tritium; Urocortins

2000
Urotensin II induces hypertrophic responses in cultured cardiomyocytes from neonatal rats.
    FEBS letters, 2001, Nov-09, Volume: 508, Issue:1

    Topics: Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly; Cell Size; Cells, Cultured; Enzyme Activation; Gene Expression; Heart; Humans; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Myocardium; Natriuretic Peptide, Brain; Phenylalanine; Protein Biosynthesis; Rats; Rats, Wistar; Urotensins

2001
CGS 34226, a thiol-based dual inhibitor of endothelin converting enzyme-1 and neutral endopeptidase 24.11.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Cell Membrane; COS Cells; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Inhibitory Concentration 50; Kidney; Male; Metalloendopeptidases; Neprilysin; Peptide Fragments; Phenylalanine; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

2002
Effects of the ECE/NEP inhibitor CGS 34225 on the big ET-1-induced pressor response and plasma atrial natriuretic peptide concentration in conscious rats.
    Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48

    Topics: Animals; Area Under Curve; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Enzyme Inhibitors; Inhibitory Concentration 50; Male; Metalloendopeptidases; Neprilysin; Peptide Fragments; Phenylalanine; Protein Precursors; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

2002
Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin.
    European journal of pharmacology, 2002, Oct-25, Volume: 453, Issue:2-3

    Topics: ADP Ribose Transferases; Amides; Animals; Atrial Natriuretic Factor; Botulinum Toxins; Cell Size; Cells, Cultured; Endothelin-1; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Mevalonic Acid; Myocytes, Cardiac; Phenylalanine; Polyisoprenyl Phosphates; Pravastatin; Protein Serine-Threonine Kinases; Pyridines; Rats; Rats, Wistar; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger

2002
B-type natriuretic peptide prevents acute hypertrophic responses in the diabetic rat heart: importance of cyclic GMP.
    Diabetes, 2003, Volume: 52, Issue:9

    Topics: Acute Disease; Animals; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Chronic Disease; Cyclic GMP; Diabetes Mellitus, Experimental; Gene Expression; Heart Ventricles; Male; Myocytes, Cardiac; Natriuretic Peptide, Brain; Phenylalanine; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tritium

2003
Dual ECE/NEP inhibition on cardiac and neurohumoral function during the transition from hypertrophy to heart failure in rats.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 45, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Cardiac Output, Low; Cardiomegaly; Collagen; Echocardiography; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Fibrosis; Heart; Male; Metalloendopeptidases; Myocardium; Neprilysin; Neurotransmitter Agents; Organophosphonates; Phenylalanine; Rats; Rats, Inbred Dahl; RNA, Messenger; Tetrazoles; Thiazepines

2005
Triple vasopeptidase inhibition normalizes blood pressure in conscious, unrestrained, and spontaneously hypertensive rats.
    American journal of hypertension, 2005, Volume: 18, Issue:12 Pt 1

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartic Acid Endopeptidases; Atrial Natriuretic Factor; Benzazepines; Benzofurans; Blood Pressure; Dose-Response Relationship, Drug; Endothelin-1; Endothelin-Converting Enzymes; Hypertension; Indoles; Male; Metalloendopeptidases; Neprilysin; Nitric Oxide; Organophosphonates; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species

2005
Structural determinants of natriuretic peptide receptor specificity and degeneracy.
    Journal of molecular biology, 2006, Aug-25, Volume: 361, Issue:4

    Topics: Amino Acid Sequence; Animals; Atrial Natriuretic Factor; Binding Sites; Crystallography, X-Ray; Dimerization; Drosophila melanogaster; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Models, Molecular; Molecular Sequence Data; Natriuretic Peptide, Brain; Natriuretic Peptide, C-Type; Phenylalanine; Protein Conformation; Receptors, Atrial Natriuretic Factor; Sequence Alignment

2006
Modelling of copper(II) binding to pentapeptides related to atrial natriuretic factor using the 3χv connectivity index.
    Arhiv za higijenu rada i toksikologiju, 2015, Volume: 66, Issue:2

    Topics: Atrial Natriuretic Factor; Binding Sites; Cations; Copper; Models, Chemical; Molecular Structure; Oligopeptides; Phenylalanine; Protein Binding; Tyrosine

2015
Amino Acid-Based Metabolic Panel Provides Robust Prognostic Value Additive to B-Natriuretic Peptide and Traditional Risk Factors in Heart Failure.
    Disease markers, 2018, Volume: 2018

    Topics: Adult; Aged; Atrial Natriuretic Factor; Biomarkers; Female; Heart Failure; Histidine; Humans; Male; Middle Aged; Ornithine; Phenylalanine; Predictive Value of Tests

2018