phenylalanine and aspartame

phenylalanine has been researched along with aspartame in 115 studies

Research

Studies (115)

Timeframe	Studies, this research(%)	All Research%
pre-1990	58 (50.43)	18.7374
1990's	35 (30.43)	18.2507
2000's	12 (10.43)	29.6817
2010's	7 (6.09)	24.3611
2020's	3 (2.61)	2.80

Authors

Authors	Studies
Bellman, K; Knegtel, RM; Settimo, L	1
Frey, GH	1
Baker, GL; Filer, LJ; McDonnell, JE; Stegink, LD	2
Baker, GL; Filer, LJ; Stegink, LD	7
Haber, M; Koch, R; Shaw, KN; Williamson, M	1
McMahon, FG; Muldoon, E; Oppermann, JA; Ranney, RE	1
Bleicher, SJ; Flores, A; Gombos, G; Recitas, D; Shu, J; Stern, SB	1
Koch, R; Schaeffler, G; Shaw, NF	1
Hutsell, TC; Mares, SE; Raczialowski, FM; Ranney, RE; Schroeder, RE	1
Addo-Yobo, F; Aracil, J; Casillas, JL; Kenney, CN; Martínez, M	1
Brisson, J; Dickie, BC; Dudley, RE; Hjelle, JJ; Kotsonis, FN; Marietta, MP; Sanders, PG	1
Berlin, CM; Mackey, SA	1
Kernan, WJ; Mullenix, PJ; Schunior, A; Tassinari, MS	1
Caccia, S; Diomede, L; Guiso, G; Romano, M; Salmona, M; Sarati, S	1
Burns, TS; Hurwitz, A; Kotsonis, FN; Stargel, WW; Tschanz, C	1
Fernstrom, JD; Fernstrom, MH; Massoudi, MS	1
Andersen, DW; Burgert, SL; Schedl, HP; Stegink, LD; Takeuchi, H	1
Blundell, JE; Keedwell, P; Rogers, PJ	1
Møller, SE	1
Li, YN; Lipton, WE; Stegink, LD; Younoszai, MK	1
Ohe, Y; Pan-Hou, H; Suda, Y; Sumi, M; Yoshioka, M	1
Caccia, S; Diomede, L; Guiso, G; Nava, S; Romano, M; Salmona, M	1
Agranoff, BW; Betz, AL; Koeppe, RA; Mangner, T; Price, JC; Rosenspire, KC; Shaw, LA; Shulkin, BL	1
Bell, EF; Brummel, MC; Filer, LJ; Persoon, TJ; Stegink, LD; Ziegler, EE	1
Bell, EF; Filer, LJ; Krause, WL; Stegink, LD; Tephly, TR; Ziegler, EE	1
Burns, TS; Hurwitz, A; Stargel, WW	1
Goddard, JE; Greenblatt, DJ; Harmatz, JS; Lapierre, KA; Shader, RI	1
Caccia, S; Diomede, L; Guiso, G; Perego, C; Romano, M; Salmona, M	1
Jadaud, P; Wainer, IW	1
Algeri, S; De Simoni, MG; Diomede, L; Fodritto, F; Garattini, S; Perego, C; Raimondi, L; Salmona, M	1
Bell, EF; Filer, LJ; Stegink, LD; Tephly, TR; Ziegler, EE	1
Levy, G; Zhi, JQ	1
Filer, LJ; Stegink, LD	1
Sze, PY	1
el-Mallakh, RS; Potenza, DP	1
Ashby, J; Cochran, C; Gorman, MA; Gupta, V; Liepa, GU; Long, DL; Parker, TF	1
Güttler, F; Lou, H	1
Sturtevant, FM	1
Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Wolf-Novak, LC; Ziegler, EE	1
Baker, GL; Bell, EF; Brummel, MC; Filer, LJ; Krause, WL; Stegink, LD; Ziegler, EE	1
Fernstrom, JD	2
Carlson, HE; Shah, JH	1
Caccia, S; Garattini, S; Guiso, G; Romano, M; Salmona, M; Stasi, MA; Vezzani, A	1
Anderson, GH; Leiter, LA	1
Janssen, PJ; van der Heijden, CA	1
Pardridge, WM	2
Karoum, F; Rapoport, JL; Zametkin, AJ	1
Maher, TJ; Wurtman, RJ	2
London, RS	1
Maher, TJ; Pinto, JM	1
Drenth, JP; Kleinjans, JC	1
Maher, TJ	1
Freedman, M	1
Bell, EF; Filer, LJ; Stegink, LD; Ziegler, EE	1
Anderson, GH; Leiter, LA; Ryan-Harshman, M	1
Dews, PB	1
Franz, M	1
Bickel, H; Trefz, FK	1
Caballero, B; Levy, HL; Mahon, BE; Rohr, FJ; Wurtman, RJ	1
Sadler, MJ	1
Caballero, B; Roberts, CH; Wurtman, RJ; Yokogoshi, H	1
Bada, JL; Boehm, MF	1
Waggoner, WF	1
Fernstrom, JD; Fernstrom, MH; Gillis, MA	1
Baker, GL; Blaskovics, ME; Filer, LJ; Koch, R; McDonnell, JE; Stegink, LD	1
Filer, LJ; Renn, E; Reynolds, WA; Stegink, LD	1
Brummel, MC; Lindgren, SD; Stegink, LD; Stumbo, PJ; Wolraich, ML	1
Anderson, GM; Gillespie, SM; Shaywitz, BA; Shaywitz, SE; Sullivan, B; Sullivan, CM	1
Blundell, JE; Rogers, PJ	1
Banich, MT; Belger, A; Bernadine, E; Stokes, AF	1
Blau, N; Curtius, HC; Endres, W	1
Gibbs, B; Konishi, Y; Luong, JH; Male, KB	1
Connors, KA; Skwierczynski, RD	1
Karstaedt, PJ; Pincus, JH	1
Hertelendy, ZI; Marshall, L; Mendenhall, CL; Rouster, SD; Weesner, R	1
Wyss, C	1
Abrams, SM; Heybroek, WM; Jackson, SH; Johnston, A; Maskrey, V; Puthrasingam, S; Swift, CG; Turner, P	1
Myers, DK; Reiner, A; Sabounjian, L; Schomer, DL; Spiers, PA; Wurtman, J	1
Månsson, MO; Mosbach, K; Ramström, O; Ye, L	1
Ansell, RJ; Månsson, MO; Mosbach, K; Ramström, O; Ye, L	1
Freudinger, R; Gekle, M; Schwerdt, G; Silbernagl, S	1
Carvalho, TS; da Silva, FB; da Silva, LC; Giugliani, R; Pereira, ML; Pires, RF	1
Benninger, C; Blackburn, GL; Butchko, HH; Comer, CP; de Sonneville, LM; Geha, RS; Hertelendy, Z; Koestner, A; Leon, AS; Liepa, GU; Mayhew, DA; McMartin, KE; Mendenhall, CL; Munro, IC; Novotny, EJ; Renwick, AG; Schiffman, SS; Schomer, DL; Shaywitz, BA; Spiers, PA; Stargel, WW; Tephly, TR; Thomas, JA; Trefz, FK	1
Hall, WL; Millward, DJ; Morgan, LM; Rogers, PJ	1
Doekel, S; Duerfahrt, T; Marahiel, MA; Quaedflieg, PJ; Sonke, T	1
Finer, N	1
Giannoulia-Karantana, A; Schulpis, KH; Simintzi, I; Tsakiris, S	1
Chen, S; Hsien, TJ	1
Angelogianni, P; Liapi, C; Schulpis, KH; Simintzi, I; Tsakiris, S	3
Humphries, P; Naudé, H; Pretorius, E	1
Abdel-Salam, OM; Ahmed, NA; El-Nagar, ME; El-Shamarka, ME; Hussein, JS; Salem, NA	1
Abhilash, M; Alex, M; Mathews, VV; Nair, RH	1
Carradori, S; Costante, R; Dvoracsko, S; Macedonio, G; Mirzaie, S; Mollica, A; Novellino, E; Stefanucci, A	1
Economopoulos, KP; Gharedaghi, MH; Gul, SS; Hamarneh, SR; Hamilton, AR; Hodin, RA; Hu, D; Huo, H; Hyoju, SK; Liu, W; Morrison, S; Munoz, AR; Phupitakphol, T; Zhang, W	1
Choudhary, AK; Lee, YY	2
Abeln, D; de Blaauw, P; Heiner-Fokkema, MR; Maatman, RGHJ; Melis, ES; van Dam, E; van Spronsen, FJ; van Vliet, K	1
Martel, F; Rodrigues, H; Silva, C	1
Alili, JM; Goetz, V; Khalil, AE; Labarthe, F; Maillot, F; Maler, V; Meunier, P; Tardieu, M	1

Reviews

13 review(s) available for phenylalanine and aspartame

Article	Year
Effect of aspartame and aspartate loading upon plasma and erythrocyte free amino acids in normal adult volunteers. Nutrition reviews, 1978, Volume: 36, Issue:4 Topics: Adult; Amino Acids; Animals; Aspartame; Aspartic Acid; Dipeptides; Erythrocytes; Fasting; Female; Glutamates; Glutamine; Humans; Male; Phenylalanine	1978
Pharmacological effects of phenylalanine on seizure susceptibility: an overview. Neurochemical research, 1989, Volume: 14, Issue:2 Topics: Animals; Aspartame; Dipeptides; Disease Models, Animal; Disease Susceptibility; Humans; Phenylalanine; Seizures	1989
Aspartame: clinical update. Connecticut medicine, 1989, Volume: 53, Issue:7 Topics: Aspartame; Dipeptides; Humans; Phenylalanine	1989
Use of aspartame in pregnancy. International journal of fertility, 1985, Volume: 30, Issue:1 Topics: Aspartame; Aspartic Acid; Digestion; Dipeptides; Female; Fetus; Humans; Methanol; Phenylalanine; Pregnancy	1985
Effects of aspartame and phenylalanine on meal-time food intake of humans. Appetite, 1988, Volume: 11 Suppl 1 Topics: Amino Acids; Aspartame; Dipeptides; Eating; Humans; Phenylalanine	1988
Aspartame: review of recent experimental and observational data. Toxicology, 1988, Volume: 50, Issue:1 Topics: Animals; Aspartame; Behavior, Animal; Brain Chemistry; Dipeptides; Humans; Phenylalanine; Phenylketonurias	1988
New directions in blood-brain barrier research. Studies with isolated human brain capillaries. Annals of the New York Academy of Sciences, 1988, Volume: 529 Topics: Alzheimer Disease; Aspartame; Blood-Brain Barrier; Capillaries; Cerebrovascular Circulation; Humans; Neurology; Peptides; Phenylalanine	1988
Possible neurologic effects of aspartame, a widely used food additive. Environmental health perspectives, 1987, Volume: 75 Topics: Animals; Aspartame; Brain; Dipeptides; Food Additives; Humans; Phenylalanine; Seizures	1987
Neurotoxicology of food additives. Neurotoxicology, 1986,Summer, Volume: 7, Issue:2 Topics: Animals; Aspartame; Blood-Brain Barrier; Dietary Carbohydrates; Dietary Proteins; Dipeptides; Emotions; Female; Food Additives; Maximum Allowable Concentration; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Inbred SHR; Seizures; Sleep Initiation and Maintenance Disorders; Tyrosine; United States; United States Food and Drug Administration	1986
Aspartame: review of safety. Regulatory toxicology and pharmacology : RTP, 2002, Volume: 35, Issue:2 Pt 2 Topics: Affect; Animals; Aspartame; Behavior; Brain Neoplasms; Cognition; Drug Evaluation, Preclinical; Drug Hypersensitivity; Electroencephalography; Endocrine System; Headache; Humans; Methanol; Phenylalanine; Product Surveillance, Postmarketing; Seizures; Sweetening Agents; Weight Loss	2002
Direct and indirect cellular effects of aspartame on the brain. European journal of clinical nutrition, 2008, Volume: 62, Issue:4 Topics: Aspartame; Aspartic Acid; Brain; Humans; Methanol; Neurotransmitter Agents; Phenylalanine; Sweetening Agents	2008
Neurophysiological symptoms and aspartame: What is the connection? Nutritional neuroscience, 2018, Volume: 21, Issue:5 Topics: Affect; Animals; Aspartame; Aspartic Acid; Brain; Cognitive Dysfunction; Disease Models, Animal; Dopamine; Free Radicals; Humans; Hydrocortisone; Migraine Disorders; Nervous System Diseases; Neurotransmitter Agents; Non-Nutritive Sweeteners; Norepinephrine; Oxidative Stress; Phenylalanine; Seizures; Serotonin; Sleep Initiation and Maintenance Disorders	2018
The debate over neurotransmitter interaction in aspartame usage. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2018, Volume: 56 Topics: Animals; Aspartame; Aspartic Acid; Brain; Dysbiosis; Humans; Hydrocortisone; Neurotransmitter Agents; Norepinephrine; Phenylalanine; Sweetening Agents	2018

Trials

26 trial(s) available for phenylalanine and aspartame

Article	Year
Use of aspartame by apparently healthy children and adolescents. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Acne Vulgaris; Adolescent; Adult; Aspartame; Body Weight; Child; Child, Preschool; Clinical Trials as Topic; Dipeptides; Female; Humans; Male; Methanol; Middle Aged; Phenylalanine; Phenylpyruvic Acids; Sucrose; Tyrosine; Visual Acuity	1976
Use of aspartame in phenylketonuric heteroxygous adults. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Adult; Aspartame; Clinical Trials as Topic; Dipeptides; Female; Heterozygote; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias; Placebos; Tyrosine	1976
Administration of aspartame in non-insulin-dependent diabetics. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Adult; Aged; Aspartame; Blood Glucose; Diabetes Mellitus; Dipeptides; Female; Humans; Male; Middle Aged; Phenylalanine; Placebos; Tyrosine	1976
Effect of dietary aspartame on plasma concentrations of phenylalanine and tyrosine in normal and homozygous phenylketonuric patients. Clinical pediatrics, 1992, Volume: 31, Issue:7 Topics: Adolescent; Adult; Aspartame; Body Weight; Child; Female; Homozygote; Humans; Male; Phenylalanine; Phenylketonurias; Sweetening Agents; Tyrosine	1992
Aspartame and sucrose produce a similar increase in the plasma phenylalanine to large neutral amino acid ratio in healthy subjects. Pharmacology, 1991, Volume: 43, Issue:4 Topics: Adult; Amino Acids; Aspartame; Blood Glucose; Female; Glucagon; Humans; Insulin; Male; Phenylalanine; Sucrose	1991
Further analysis of the short-term inhibition of food intake in humans by the dipeptide L-aspartyl-L-phenylalanine methyl ester (aspartame). Physiology & behavior, 1991, Volume: 49, Issue:4 Topics: Adult; Appetite; Aspartame; Aspartic Acid; Dose-Response Relationship, Drug; Double-Blind Method; Feeding Behavior; Female; Humans; Hunger; Male; Neural Inhibition; Phenylalanine; Satiety Response	1991
Effect of sucrose on the metabolic disposition of aspartame. The American journal of clinical nutrition, 1990, Volume: 52, Issue:2 Topics: Adult; Alanine; Amino Acids, Branched-Chain; Aspartame; Aspartic Acid; Beverages; Blood Glucose; Dietary Carbohydrates; Dipeptides; Female; Humans; Insulin; Male; Phenylalanine; Sucrose	1990
Repeated ingestion of aspartame-sweetened beverages: further observations in individuals heterozygous for phenylketonuria. Metabolism: clinical and experimental, 1990, Volume: 39, Issue:10 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Beverages; Female; Heterozygote; Humans; Male; Methanol; Phenylalanine; Phenylketonurias	1990
Bioavailability of phenylalanine and aspartate from aspartame (20 mg/kg) in capsules and solution. Metabolism: clinical and experimental, 1990, Volume: 39, Issue:11 Topics: Adolescent; Adult; Amino Acids; Aspartame; Aspartic Acid; Biological Availability; Capsules; Female; Humans; Male; Osmolar Concentration; Phenylalanine; Random Allocation; Solutions; Tyrosine	1990
The neuropsychiatric effects of aspartame in normal volunteers. Journal of clinical pharmacology, 1990, Volume: 30, Issue:5 Topics: Administration, Oral; Adult; Affect; Amino Acids; Aspartame; Blood Glucose; Cognition; Dipeptides; Double-Blind Method; Female; Humans; Male; Memory; Phenylalanine; Product Surveillance, Postmarketing; Random Allocation; Reaction Time; Time Factors	1990
Effect of aspartame on plasma amino acid profiles of diabetic patients with chronic renal failure. The American journal of clinical nutrition, 1989, Volume: 49, Issue:6 Topics: Amino Acids; Aspartame; Diabetic Nephropathies; Dipeptides; Female; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Phenylalanine; Renal Dialysis; Tyrosine	1989
Aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults and adults heterozygous for phenylketonuria. The Journal of nutrition, 1987, Volume: 117, Issue:11 Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Biological Transport; Dipeptides; Female; Glutamates; Glutamic Acid; Glutamine; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias; Tyrosine	1987
Repeated ingestion of aspartame-sweetened beverage: effect on plasma amino acid concentrations in individuals heterozygous for phenylketonuria. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:1 Topics: Adult; Amino Acids; Aspartame; Beverages; Biological Transport; Dipeptides; Dose-Response Relationship, Drug; Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias; Random Allocation	1989
Treatment of hyperactive children with D-phenylalanine. The American journal of psychiatry, 1987, Volume: 144, Issue:6 Topics: Aspartame; Attention Deficit Disorder with Hyperactivity; Child; Clinical Trials as Topic; Double-Blind Method; Humans; Isomerism; Male; Phenylalanine; Psychiatric Status Rating Scales; Psychomotor Performance	1987
Repeated ingestion of aspartame-sweetened beverage: effect on plasma amino acid concentrations in normal adults. Metabolism: clinical and experimental, 1988, Volume: 37, Issue:3 Topics: Adult; Amino Acids; Aspartame; Beverages; Biological Transport; Brain; Dietary Proteins; Dipeptides; Female; Humans; Male; Phenylalanine; Tyrosine	1988
Plasma amino acid concentrations in normal adults administered aspartame in capsules or solution: lack of bioequivalence. Metabolism: clinical and experimental, 1987, Volume: 36, Issue:5 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Biological Availability; Capsules; Dipeptides; Female; Humans; Kinetics; Male; Phenylalanine; Solutions; Tyrosine	1987
Effect of aspartame plus monosodium L-glutamate ingestion on plasma and erythrocyte amino acid levels in normal adult subjects fed a high protein meal. The American journal of clinical nutrition, 1982, Volume: 36, Issue:6 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Dietary Proteins; Digestive System; Dipeptides; Erythrocytes; Female; Glutamates; Humans; Male; Phenylalanine; Random Allocation; Sodium Glutamate	1982
Effect of aspartame and sucrose loading in glutamate-susceptible subjects. The American journal of clinical nutrition, 1981, Volume: 34, Issue:9 Topics: Aspartame; Aspartic Acid; Dipeptides; Double-Blind Method; Female; Glutamates; Headache; Humans; Male; Nausea; Phenylalanine; Sodium Glutamate; Sucrose	1981
Erythrocyte L-aspartyl-L-phenylalanine hydrolase activity and plasma phenylalanine and aspartate concentrations in children consuming diets high in aspartame. The American journal of clinical nutrition, 1995, Volume: 62, Issue:6 Topics: Aging; Analysis of Variance; Aspartame; Aspartic Acid; Child; Child Behavior; Child, Preschool; Cognition; Diet; Dose-Response Relationship, Drug; Double-Blind Method; Erythrocytes; Humans; Hydrolases; Phenylalanine; Sweetening Agents	1995
Aspartame, behavior, and cognitive function in children with attention deficit disorder. Pediatrics, 1994, Volume: 93, Issue:1 Topics: Adolescent; Aspartame; Attention Deficit Disorder with Hyperactivity; Catecholamines; Child; Child Behavior; Child, Preschool; Cognition; Double-Blind Method; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Phenylalanine	1994
Reanalysis of the effects of phenylalanine, alanine, and aspartame on food intake in human subjects. Physiology & behavior, 1994, Volume: 56, Issue:2 Topics: Adult; Alanine; Appetite; Aspartame; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Eating; Humans; Male; Phenylalanine	1994
Effects of alcohol and chronic aspartame ingestion upon performance in aviation relevant cognitive tasks. Aviation, space, and environmental medicine, 1994, Volume: 65, Issue:1 Topics: Aerospace Medicine; Aspartame; Aviation; Cognition; Double-Blind Method; Ethanol; Humans; Phenylalanine; Psychomotor Performance	1994
Aspartame use in Parkinson's disease. Neurology, 1993, Volume: 43, Issue:3 Pt 1 Topics: Aged; Aspartame; Humans; Levodopa; Middle Aged; Parkinson Disease, Secondary; Phenylalanine	1993
Biochemical and clinical effects of aspartame in patients with chronic, stable alcoholic liver disease. The American journal of gastroenterology, 1993, Volume: 88, Issue:5 Topics: Amino Acids; Animals; Aspartame; Drug Evaluation; Hepatic Encephalopathy; Humans; Liver; Liver Diseases, Alcoholic; Male; Methanol; Middle Aged; Milk; Phenylalanine; Risk Factors	1993
Aspartame: neuropsychologic and neurophysiologic evaluation of acute and chronic effects. The American journal of clinical nutrition, 1998, Volume: 68, Issue:3 Topics: Adult; Aspartame; Behavior; Blood Glucose; Cognition; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Humans; Male; Nervous System; Phenylalanine; Psychological Tests	1998
Physiological mechanisms mediating aspartame-induced satiety. Physiology & behavior, 2003, Volume: 78, Issue:4-5 Topics: Adult; Appetite; Aspartame; Aspartic Acid; Blood Glucose; Cholecystokinin; Cross-Over Studies; Diet; Female; Gastric Emptying; Glucagon; Glucagon-Like Peptide 1; Hormones; Humans; Insulin; Male; Peptide Fragments; Phenylalanine; Protein Precursors; Satiety Response; Sweetening Agents	2003

Other Studies

76 other study(ies) available for phenylalanine and aspartame

Article	Year
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Effect of aspartame loading upon plasma and erythrocyte amino acid levels in phenylketonuric heterozygotes and normal adult subjects. The Journal of nutrition, 1979, Volume: 109, Issue:4 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Erythrocytes; Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias	1979
Plasma, erythrocyte and human milk levels of free amino acids in lactating women administered aspartame or lactose. The Journal of nutrition, 1979, Volume: 109, Issue:12 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Breast Feeding; Dipeptides; Erythrocytes; Female; Humans; Infant; Infant, Newborn; Lactation; Lactose; Milk, Human; Phenylalanine; Pregnancy	1979
Comparative metabolism of aspartame in experimental animals and humans. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Animals; Aspartame; Aspartic Acid; Carbon Radioisotopes; Dipeptides; Dogs; Haplorhini; Humans; Methanol; Mice; Phenylalanine; Rabbits; Rats	1976
Effect of aspartame and aspartate loading upon plasma and erythrocyte free amino acid levels in normal adult volunteers. The Journal of nutrition, 1977, Volume: 107, Issue:10 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Energy Intake; Erythrocytes; Female; Humans; Male; Phenylalanine	1977
Results of loading doses of aspartame by two phenylketonuric (PKU) children compared with two normal children. Journal of toxicology and environmental health, 1976, Volume: 2, Issue:2 Topics: Adolescent; Aspartame; Child; Dipeptides; Female; Glutamine; Humans; Male; Phenylacetates; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Tyrosine	1976
The phenylalanine and tyrosine contnet of maternal and fetal body fluids from rabbits fed aspartame. Toxicology and applied pharmacology, 1975, Volume: 32, Issue:2 Topics: Amino Acids; Amniotic Fluid; Animals; Aspartame; Body Fluids; Body Weight; Dipeptides; Female; Fetus; Gestational Age; Maternal-Fetal Exchange; Phenylalanine; Phenylalanine Hydroxylase; Pregnancy; Rabbits; Tyrosine	1975
The use of modified divinylbenzene-polystyrene resins in the separation of fermentation products. A case study utilizing amino acids and a dipeptide. Journal of chemical technology and biotechnology (Oxford, Oxfordshire : 1986), 1992, Volume: 55, Issue:2 Topics: Adsorption; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Chromatography, High Pressure Liquid; Dipeptides; Fermentation; Hydrogen-Ion Concentration; Kinetics; Osmolar Concentration; Phenylalanine; Polystyrenes; Resins, Plant; Temperature; Thermodynamics; Vinyl Compounds	1992
Plasma concentrations and pharmacokinetics of phenylalanine in rats and mice administered aspartame. Pharmacology, 1992, Volume: 44, Issue:1 Topics: Administration, Oral; Amino Acids; Animals; Aspartame; Humans; Male; Mice; Mice, Inbred ICR; Phenylalanine; Random Allocation; Rats; Rats, Inbred Strains; Tyrosine	1992
No change in spontaneous behavior of rats after acute oral doses of aspartame, phenylalanine, and tyrosine. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1991, Volume: 16, Issue:3 Topics: Animals; Aspartame; Behavior, Animal; Central Nervous System; Data Interpretation, Statistical; Dextroamphetamine; Male; Motor Activity; Neurotransmitter Agents; Phenylalanine; Rats; Rats, Inbred Strains; Tyrosine	1991
Effect of tyrosine on the potentiation by aspartame and phenylalanine of metrazol-induced convulsions in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:12 Topics: Animals; Aspartame; Brain; Drug Interactions; Male; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Tyrosine	1991
In vivo tyrosine hydroxylation in rat retina: effect of aspartame ingestion in rats pretreated with p-chlorophenylalanine. The American journal of clinical nutrition, 1991, Volume: 53, Issue:4 Topics: Animals; Aspartame; Dihydroxyphenylalanine; Fenclonine; Hydroxylation; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Inbred Strains; Retina; Tyrosine	1991
Metabolism of aspartame and its L-phenylalanine methyl ester decomposition product by the porcine gut. Metabolism: clinical and experimental, 1991, Volume: 40, Issue:6 Topics: Animals; Aspartame; Aspartic Acid; Female; Intestinal Absorption; Intestine, Small; Kinetics; Liver Circulation; Methanol; Perfusion; Phenylalanine; Swine; Tyrosine	1991
Effect of aspartame and protein, administered in phenylalanine-equivalent doses, on plasma neutral amino acids, aspartate, insulin and glucose in man. Pharmacology & toxicology, 1991, Volume: 68, Issue:5 Topics: Adult; Amino Acids; Aspartame; Aspartic Acid; Blood Glucose; Brain; Humans; Insulin; Male; Metabolic Clearance Rate; Phenylalanine; Serum Albumin, Bovine	1991
Intestinal absorption of aspartame decomposition products in adult rats. Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12 Topics: Absorption; Animals; Aspartame; Catalysis; Dipeptides; Escherichia coli; Hydrolysis; Intestinal Mucosa; Liver; Male; Models, Biological; Osmolar Concentration; Phenylalanine; Rats; Rats, Inbred Strains	1991
Effect of aspartame on N-methyl-D-aspartate-sensitive L-[3H]glutamate binding sites in rat brain synaptic membranes. Brain research, 1990, Jun-18, Volume: 520, Issue:1-2 Topics: Animals; Aspartame; Aspartic Acid; Brain; Dipeptides; Glutamates; Glutamic Acid; Kinetics; Male; N-Methylaspartate; Phenylalanine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes	1990
Interspecies and interstrain studies on the increased susceptibility to metrazol-induced convulsions in animals given aspartame. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:2 Topics: Animals; Aspartame; Brain; Drug Synergism; Guinea Pigs; Kinetics; Male; Mice; Mice, Inbred DBA; Pentylenetetrazole; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Species Specificity; Tyrosine	1991
Effect of aspartame-derived phenylalanine on neutral amino acid uptake in human brain: a positron emission tomography study. Journal of neurochemistry, 1991, Volume: 56, Issue:5 Topics: Amino Acids; Aspartame; Biological Transport; Brain; Cyclohexanecarboxylic Acids; Humans; Male; Phenylalanine; Tissue Distribution; Tomography, Emission-Computed	1991
Plasma and brain kinetics of large neutral amino acids and of striatum monoamines in rats given aspartame. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1990, Volume: 28, Issue:5 Topics: Animals; Aspartame; Biogenic Monoamines; Corpus Striatum; Dipeptides; Phenylalanine; Rats; Rats, Inbred Strains; Time Factors; Tyrosine	1990
The stereochemical resolution of the enantiomers of aspartame on an immobilized alpha-chymotrypsin HPLC chiral stationary phase: the effect of mobile-phase composition and enzyme activity. Chirality, 1990, Volume: 2, Issue:1 Topics: Acylation; Aspartame; Binding Sites; Chromatography, High Pressure Liquid; Chymotrypsin; Dipeptides; Enzymes, Immobilized; Phenylalanine; Stereoisomerism	1990
Aspartame and the rat brain monoaminergic system. Toxicology letters, 1988, Volume: 44, Issue:3 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartame; Biogenic Monoamines; Brain; Chromatography, High Pressure Liquid; Corpus Striatum; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Electrodes, Implanted; Hippocampus; Hydroxyindoleacetic Acid; Nucleus Accumbens; Phenylalanine; Plasma; Rats; Serotonin; Tyrosine	1988
Effect of repeated ingestion of aspartame-sweetened beverage on plasma amino acid, blood methanol, and blood formate concentrations in normal adults. Metabolism: clinical and experimental, 1989, Volume: 38, Issue:4 Topics: Adult; Amino Acids; Asparagine; Aspartame; Aspartic Acid; Beverages; Dipeptides; Female; Formates; Glutamates; Glutamic Acid; Glutamine; Humans; Male; Methanol; Phenylalanine; Tryptophan; Tyrosine	1989
Aspartame and phenylalanine do not enhance theophylline-induced seizures in rats. Research communications in chemical pathology and pharmacology, 1989, Volume: 66, Issue:1 Topics: Animals; Aspartame; Body Temperature; Body Weight; Dipeptides; Drug Interactions; Female; Phenylalanine; Rats; Rats, Inbred Strains; Seizures; Theophylline	1989
Aspartame metabolism in normal adults, phenylketonuric heterozygotes, and diabetic subjects. Diabetes care, 1989, Volume: 12, Issue:1 Topics: Adult; Aspartame; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptides; Erythrocytes; Female; Glucagon; Heterozygote; Humans; Insulin; Lipids; Male; Methanol; Phenylalanine; Phenylketonurias; Reference Values	1989
Aspartame may imperil dietary control of phenylketonuria. Lancet (London, England), 1985, Mar-02, Volume: 1, Issue:8427 Topics: Aspartame; Child; Dipeptides; Humans; Phenylalanine; Phenylketonurias	1985
Aspartame. Review of safety issues. Council on Scientific Affairs. JAMA, 1985, Jul-19, Volume: 254, Issue:3 Topics: Adolescent; Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Brain Diseases; Brain Neoplasms; Carbonated Beverages; Carcinogens; Child; Dietary Carbohydrates; Diketopiperazines; Dipeptides; Drug Stability; Endocrine System Diseases; Female; Glutamates; Glutamic Acid; Humans; Infant; Intellectual Disability; Methanol; Mice; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Piperazines; Pregnancy; Rats	1985
Oral aspartame and plasma phenylalanine: pharmacokinetic difference between rodents and man, and relevance to CNS effects of phenylalanine. Short note. Journal of neural transmission, 1989, Volume: 75, Issue:2 Topics: Administration, Oral; Animals; Aspartame; Brain Chemistry; Dipeptides; Humans; Phenylalanine; Rats; Species Specificity	1989
Aspartame and its constituent amino acids: effects on prolactin, cortisol, growth hormone, insulin, and glucose in normal humans. The American journal of clinical nutrition, 1989, Volume: 49, Issue:3 Topics: Administration, Oral; Adult; Aspartame; Aspartic Acid; Blood Glucose; Dipeptides; Female; Growth Hormone; Humans; Hydrocortisone; Male; Phenylalanine; Prolactin	1989
Effect of aspartame on seizures in various models of experimental epilepsy. Toxicology and applied pharmacology, 1988, Volume: 96, Issue:3 Topics: Animals; Aspartame; Brain Chemistry; Dipeptides; Electroshock; Epilepsy; Male; Pentylenetetrazole; Phenylalanine; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tyrosine	1988
Saccharin and aspartame. Are they safe to consume during pregnancy? The Journal of reproductive medicine, 1988, Volume: 33, Issue:1 Topics: Aspartame; Aspartic Acid; Dipeptides; Female; Humans; Methanol; Phenylalanine; Pregnancy; Saccharin	1988
Administration of aspartame potentiates pentylenetetrazole- and fluorothyl-induced seizures in mice. Neuropharmacology, 1988, Volume: 27, Issue:1 Topics: Animals; Aspartame; Dipeptides; Dose-Response Relationship, Drug; Drug Synergism; Flurothyl; Male; Mice; Pentylenetetrazole; Phenylalanine; Seizures; Tyrosine	1988
[Aspartame, a sweet alternative]. Nederlands tijdschrift voor geneeskunde, 1988, Apr-16, Volume: 132, Issue:16 Topics: Adolescent; Adult; Animals; Aspartame; Carcinogens; Child; Child, Preschool; Dipeptides; Energy Intake; Energy Metabolism; Humans; Phenylalanine; Phenylketonurias; Rats	1988
Consumption of aspartame by heterozygotes for phenylketonuria. The Journal of pediatrics, 1987, Volume: 110, Issue:4 Topics: Aspartame; Dipeptides; Female; Fetal Diseases; Heterozygote; Humans; Phenylalanine; Phenylketonurias; Pregnancy	1987
Phenylalanine and aspartame fail to alter feeding behavior, mood and arousal in men. Physiology & behavior, 1987, Volume: 39, Issue:2 Topics: Adult; Amino Acids; Arousal; Aspartame; Dipeptides; Feeding Behavior; Humans; Male; Osmolar Concentration; Phenylalanine	1987
The safety of aspartame. JAMA, 1987, Jul-10, Volume: 258, Issue:2 Topics: Aspartame; Dipeptides; Female; Humans; Intelligence; Maternal-Fetal Exchange; Phenylalanine; Pregnancy	1987
Summary report of an International Aspartame Workshop. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1987, Volume: 25, Issue:7 Topics: Animals; Aspartame; Biotransformation; Dipeptides; Female; Humans; Phenylalanine; Phenylketonurias; Pregnancy	1987
Is it safe to consume aspartame during pregnancy? A review. Nutrition update. The Diabetes educator, 1986,Spring, Volume: 12, Issue:2 Topics: Adolescent; Adult; Aspartame; Child; Child, Preschool; Dipeptides; Female; Humans; Infant; Lactation; Male; Methanol; Phenylalanine; Pregnancy	1986
Effects of oral aspartame on plasma phenylalanine in humans and experimental rodents. Short note. Journal of neural transmission, 1987, Volume: 70, Issue:1-2 Topics: Administration, Oral; Animals; Aspartame; Dipeptides; Humans; Mice; Phenylalanine; Rodentia; Tyrosine	1987
[Aspartame: a sweetening agent with a high phenylalanine content]. Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:7 Topics: Aspartame; Child; Dipeptides; Genetic Carrier Screening; Humans; Phenylalanine; Phenylketonurias; Risk	1986
Plasma amino acid levels after single-dose aspartame consumption in phenylketonuria, mild hyperphenylalaninemia, and heterozygous state for phenylketonuria. The Journal of pediatrics, 1986, Volume: 109, Issue:4 Topics: Amino Acids; Aspartame; Dipeptides; Heterozygote; Humans; Phenylalanine; Phenylketonurias	1986
The safety of aspartame. JAMA, 1986, Nov-21, Volume: 256, Issue:19 Topics: Adult; Aspartame; Brain Diseases; Child; Dipeptides; Humans; Phenylalanine	1986
Effect of aspartame loading on plasma and erythrocyte free amino acid concentrations in one-year-old infants. The Journal of nutrition, 1983, Volume: 113, Issue:8 Topics: Adult; Age Factors; Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Erythrocytes; Glutamates; Glutamic Acid; Humans; Infant; Phenylalanine; Tyrosine	1983
Recent aspartame studies. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1984, Volume: 22, Issue:9 Topics: Adult; Animals; Aspartame; Aspartic Acid; Brain Chemistry; Dipeptides; Drug Interactions; Glutamates; Glutamic Acid; Humans; Infant; Methanol; Phenylalanine; Sodium Glutamate	1984
Effects of aspartame and glucose administration on brain and plasma levels of large neutral amino acids and brain 5-hydroxyindoles. The American journal of clinical nutrition, 1984, Volume: 40, Issue:1 Topics: Amino Acids; Animals; Aspartame; Brain; Dipeptides; Drug Interactions; Glucose; Hydroxyindoleacetic Acid; Male; Phenylalanine; Rats; Rats, Inbred Strains; Serotonin; Tyrosine	1984
Racemization of aspartic acid and phenylalanine in the sweetener aspartame at 100 degrees C. Proceedings of the National Academy of Sciences of the United States of America, 1984, Volume: 81, Issue:16 Topics: Aspartame; Aspartic Acid; Dipeptides; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Stereoisomerism	1984
Aspartame--a review. Pediatric dentistry, 1984, Volume: 6, Issue:3 Topics: Animals; Aspartame; Brain Diseases; Brain Neoplasms; Child; Dental Caries; Dipeptides; Humans; Phenylalanine; Phenylketonurias; United States; United States Food and Drug Administration	1984
Acute effects of aspartame on large neutral amino acids and monoamines in rat brain. Life sciences, 1983, Apr-04, Volume: 32, Issue:14 Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Aspartame; Brain; Catecholamines; Dipeptides; Male; Phenylalanine; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine	1983
Levels of free amino acids in lactating women following ingestion of the sweetener aspartame. Nutrition reviews, 1980, Volume: 38, Issue:5 Topics: Adult; Aspartame; Dipeptides; Female; Humans; Lactation; Lactose; Phenylalanine; Pregnancy; Tyrosine	1980
Plasma and erythrocyte concentrations of free amino acids in adult humans administered abuse doses of aspartame. Journal of toxicology and environmental health, 1981, Volume: 7, Issue:2 Topics: Adult; Alanine; Alanine Transaminase; Amino Acids; Aspartame; Aspartate Aminotransferases; Dipeptides; Erythrocytes; Female; Humans; Male; Phenylalanine; Plasma; Tyrosine	1981
Plasma phenylalanine levels in phenylketonuric heterozygous and normal adults administered aspartame at 34 mg/kg body weight. Toxicology, 1981, Volume: 20, Issue:1 Topics: Adult; Aspartame; Aspartic Acid; Dipeptides; Female; Heterozygote; Humans; Male; Phenylalanine; Phenylketonurias; Sex Factors; Tyrosine	1981
Effect of an abuse dose of aspartame upon plasma and erythrocyte levels of amino acids in phenylketonuric heterozygous and normal adults. The Journal of nutrition, 1980, Volume: 110, Issue:11 Topics: Amino Acids; Aspartame; Aspartic Acid; Dipeptides; Dose-Response Relationship, Drug; Erythrocytes; Female; Heterozygote; Humans; Kinetics; Male; Phenylalanine; Phenylketonurias	1980
Aspartame administration to the infant monkey: hypothalamic morphology and plasma amino acid levels. The Anatomical record, 1980, Volume: 198, Issue:1 Topics: Amino Acids; Animals; Aspartame; Aspartic Acid; Dipeptides; Female; Glutamates; Hypothalamus; Macaca; Macaca fascicularis; Macaca mulatta; Male; Phenylalanine; Sodium Glutamate; Tyrosine	1980
Effect of high-protein meal plus aspartame ingestion on plasma phenylalanine concentrations in obligate heterozygotes for phenylketonuria. Metabolism: clinical and experimental, 1994, Volume: 43, Issue:4 Topics: Adult; Aspartame; Brain; Dietary Proteins; Female; Heterozygote; Humans; Male; Middle Aged; Phenylalanine; Phenylketonurias	1994
An improved FIA biosensor for the determination of aspartame in dietary food products. Applied biochemistry and biotechnology, 1993, Volume: 38, Issue:3 Topics: Aspartame; Biosensing Techniques; Electrodes; Enzymes, Immobilized; Flow Injection Analysis; Food Analysis; Glass; Phenylalanine; Pronase	1993
Demethylation kinetics of aspartame and L-phenylalanine methyl ester in aqueous solution. Pharmaceutical research, 1993, Volume: 10, Issue:8 Topics: Aspartame; Chromatography, High Pressure Liquid; Dealkylation; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Phenylalanine; Potentiometry; Solutions; Water	1993
Aspartame as a source of essential phenylalanine for the growth of oral anaerobes. FEMS microbiology letters, 1993, Apr-15, Volume: 108, Issue:3 Topics: Aspartame; Bacteria, Anaerobic; Dental Plaque; Humans; Phenylalanine; Species Specificity	1993
Aspartame pharmacokinetics - the effect of ageing. Age and ageing, 1996, Volume: 25, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Aging; Aspartame; Female; Humans; Male; Metabolic Clearance Rate; Phenylalanine; Pilot Projects; Reference Values	1996
A new application of molecularly imprinted materials. Journal of molecular recognition : JMR, 1998,Winter, Volume: 11, Issue:1-6 Topics: Adsorption; Aspartame; Aspartic Acid; In Vitro Techniques; Molecular Mimicry; Phenylalanine; Polymers; Thermolysin	1998
Use of molecularly imprinted polymers in a biotransformation process. Biotechnology and bioengineering, 1999, Sep-20, Volume: 64, Issue:6 Topics: Aspartame; Aspartic Acid; Biotransformation; Methacrylates; Phenylalanine; Polymers; Thermolysin	1999
Ochratoxin A-binding proteins in rat organs and plasma and in different cell lines of the kidney. Toxicology, 1999, Jul-01, Volume: 135, Issue:1 Topics: Animals; Aspartame; Binding, Competitive; Blood Proteins; Cell Line; Kidney; Mycotoxins; Ochratoxins; Phenylalanine; Protein Binding; Proteins; Rats; Subcellular Fractions	1999
Aspartame loading test in PKU heterozygous individuals bearing severe and moderate mutations. Clinical genetics, 2000, Volume: 58, Issue:1 Topics: Aspartame; DNA; DNA Mutational Analysis; Heterozygote; Humans; Mutation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Tyrosine	2000
Construction of hybrid peptide synthetases for the production of alpha-l-aspartyl-l-phenylalanine, a precursor for the high-intensity sweetener aspartame. European journal of biochemistry, 2003, Volume: 270, Issue:22 Topics: Aspartame; Aspartic Acid; Catalysis; Chromatography, High Pressure Liquid; Dipeptides; Escherichia coli; Mass Spectrometry; Peptide Synthases; Phenylalanine; Protein Engineering; Recombinant Proteins; Substrate Specificity	2003
Aspartame and its effects on health: approach seems simplistic in electronic responses to editorial. BMJ (Clinical research ed.), 2005, Feb-05, Volume: 330, Issue:7486 Topics: Aspartame; Formaldehyde; Formates; Health; Humans; Methanol; Phenylalanine; Sweetening Agents	2005
The effect of aspartame metabolites on human erythrocyte membrane acetylcholinesterase activity. Pharmacological research, 2006, Volume: 53, Issue:1 Topics: Acetylcholinesterase; Adult; Aspartame; Aspartic Acid; Erythrocyte Membrane; Humans; Methanol; Phenylalanine	2006
A facile HPLC method for optical purity and quantitative measurements of phenylalanine from the hydrolyzed aspartame under different pH and temperature after its derivatization with a fluorescent reagent. Amino acids, 2007, Volume: 33, Issue:1 Topics: Aspartame; Chromatography, High Pressure Liquid; Fluorenes; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Phenylalanine; Stereoisomerism; Sweetening Agents	2007
The effect of aspartame on acetylcholinesterase activity in hippocampal homogenates of suckling rats. Pharmacological research, 2007, Volume: 56, Issue:2 Topics: Acetylcholinesterase; Animals; Animals, Suckling; Aspartame; Aspartic Acid; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Electrophorus; Hippocampus; In Vitro Techniques; Kinetics; Methanol; Phenylalanine; Rats; Rats, Wistar; Subcellular Fractions; Sweetening Agents	2007
L-Cysteine and glutathione restore the reduction of rat hippocampal Na+, K+-ATPase activity induced by aspartame metabolites. Toxicology, 2007, Jul-31, Volume: 237, Issue:1-3 Topics: Animals; Animals, Suckling; Aspartame; Aspartic Acid; Cysteine; Dose-Response Relationship, Drug; Female; Glutathione; Hippocampus; In Vitro Techniques; Male; Methanol; Phenylalanine; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sweetening Agents	2007
Aspartame effects on the brain. European journal of clinical nutrition, 2009, Volume: 63, Issue:5 Topics: Animals; Aspartame; Brain; Humans; Neurotoxins; Phenylalanine; Rats; Sweetening Agents	2009
l-Cysteine and glutathione restore the modulation of rat frontal cortex Na+, K+ -ATPase activity induced by aspartame metabolites. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:6 Topics: Animals; Animals, Suckling; Antioxidants; Aspartame; Aspartic Acid; Biotransformation; Ca(2+) Mg(2+)-ATPase; Cysteine; Female; Glutathione; Male; Phenylalanine; Prefrontal Cortex; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Sweetening Agents	2008
Studies on the effects of aspartame on memory and oxidative stress in brain of mice. European review for medical and pharmacological sciences, 2012, Volume: 16, Issue:15 Topics: Animals; Aspartame; Brain; Male; Malondialdehyde; Memory; Mice; Nitric Oxide; Oxidative Stress; Phenylalanine	2012
Chronic Effect of Aspartame on Ionic Homeostasis and Monoamine Neurotransmitters in the Rat Brain. International journal of toxicology, 2014, Volume: 33, Issue:4 Topics: Animals; Apoptosis; Aspartame; Cerebral Cortex; Corpus Striatum; Dopamine Antagonists; Male; Nerve Tissue Proteins; Neurons; Neurotoxicity Syndromes; Non-Nutritive Sweeteners; Phenylalanine; Random Allocation; Rats, Wistar; Serotonin Antagonists; Sodium-Potassium-Exchanging ATPase; Toxicity Tests, Chronic; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase; Water-Electrolyte Imbalance	2014
Exploring the biological consequences of conformational changes in aspartame models containing constrained analogues of phenylalanine. Journal of enzyme inhibition and medicinal chemistry, 2016, Volume: 31, Issue:6 Topics: Aspartame; Dose-Response Relationship, Drug; Models, Molecular; Molecular Conformation; Phenylalanine; Structure-Activity Relationship; Sweetening Agents	2016
Inhibition of the gut enzyme intestinal alkaline phosphatase may explain how aspartame promotes glucose intolerance and obesity in mice. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2017, Volume: 42, Issue:1 Topics: Alkaline Phosphatase; Animals; Aspartame; Biomarkers; Biotransformation; Blood Glucose; Diet, High-Fat; Enzyme Inhibitors; Glucose Intolerance; Insulin Resistance; Intestinal Mucosa; Intestine, Small; Male; Metabolic Syndrome; Mice, Inbred C57BL; Non-Nutritive Sweeteners; Obesity; Phenylalanine; Tumor Necrosis Factor-alpha; Weight Gain	2017
Aspartame and Phe-Containing Degradation Products in Soft Drinks across Europe. Nutrients, 2020, Jun-24, Volume: 12, Issue:6 Topics: Aspartame; Carbonated Beverages; Chromatography, Liquid; Diketopiperazines; Dipeptides; Europe; Food Safety; Humans; Limit of Detection; Phenylalanine; Phenylketonurias; Reproducibility of Results; Tandem Mass Spectrometry	2020
The effects of aspartame on the HTR8/SVneo extravillous trophoblast cell line. Reproductive biology, 2022, Volume: 22, Issue:3 Topics: Aspartame; Aspartic Acid; Cell Line; Cell Movement; Female; Glucose; Humans; Methanol; Phenylalanine; Placenta; Pregnancy; Trophoblasts	2022
Aspartame and Phenylketonuria: an analysis of the daily phenylalanine intake of aspartame-containing drugs marketed in France. Orphanet journal of rare diseases, 2023, 06-08, Volume: 18, Issue:1 Topics: Aspartame; France; Humans; Phenylalanine; Phenylketonurias	2023