phenylalanine and alpha-methylphenylalanine

phenylalanine has been researched along with alpha-methylphenylalanine in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-199022 (53.66)18.7374
1990's10 (24.39)18.2507
2000's6 (14.63)29.6817
2010's2 (4.88)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Bonini, BM; Thevelein, JM; Van Zeebroeck, G; Versele, M1
Delvalle, JA; Dienel, G; Greengard, O1
Del Valle, JA; Greengard, O1
Gerren, RA; Luttges, MW1
Del Valle, JA; Greengard, O; Yoss, MS1
Camargo, MM; Pureur, RP; Rubin, MA; Valente, GB; Wannmacher, CM1
Dutra-Filho, CS; Fagan, PR; Pires, RF; Rodrigues, NR; Wajner, M; Wannmacher, CM1
Greengard, O; Wolfe, J1
Castillo, M; Garcia-Peregrin, E; Zafra, MF2
Johnson, RC; Shah, SN2
Benevenga, NJ; Steele, RD1
Lane, JD; Langenbeck, U; Neuhoff, V; Schöne, B1
Lane, JD; Neuhoff, V1
Berry, HK; Butcher, RE; Vorhees, CV1
Blumstein, L; Levitsky, DA; Strupp, BJ1
Brass, CA; Greengard, O2
Dougan, DF; Duffield, AM; Duffield, PH; Wade, DN1
Huether, G; Neuhoff, V1
Binek-Singer, P; Johnson, TC1
Brass, CA; Greengard, O; Isaacs, CE; McChesney, R1
Binek, PA; Johnson, TC; Kelly, CJ1
Burri, R; Herschkowitz, N; Reynolds, R1
Ciaramitaro, V; Diamond, A; Djali, S; Donner, E; Robinson, MB1
Camargo, MM; de Freitas, MS; de Mattos, AG; Pessoa-Pureur, R; Wannmacher, CM1
Cunha-Filho, JS; Milton, C; Sarkis, JJ; Schetinger, MR; Teixeira, MV; Wajner, M; Wannmacher, D; Wyse, AT1
Allen, JF; Harrison, MA; Keen, JN; Nore, BF1
Charland, S; Filteau, C; Gobeil, F; Neugebauer, W; Perron, SI; Regoli, D1
Austic, RE; Levitsky, DA; Strupp, BJ; Su, CL1
Borges, LF; Floriano, PJ; Noriler, ME; Silva, CG; Wajner, M; Wannmacher, CM; Wyse, AT1
Bridi, R; Dutra-Filho, CS; Kienzle Hagen, ME; Pederzolli, CD; Sgaravatti, AM; Wajner, M; Wannmacher, CM; Wyse, AT1
Chase, TN; Kupfer, DJ; Scott, J; Snyder, F; Wyatt, RJ1
Costabeber, E; de Souza Wyse, AT; Kessler, A; Severo Dutra-Filho, C; Wajner, M; Wannmacher, CM1
Bindu, LK; Burke, TR; Fisher, RJ; Kang, SU; Karki, RG; Nicklaus, MC; Oishi, S; Wang, X; Worthy, KM1
Ichikawa, Y; Isobe, M; Yamauchi, E1
Eriksson, M; Fandrick, K; Grinberg, N; Lee, H; Ma, S; Senanayake, C; Shen, S; Xu, J; Yee, N; Zeng, X1
Arano, Y; Endo, K; Hanaoka, H; Ishioka, NS; Kanai, Y; Nagamori, S; Ohshima, Y; Suzuki, Y; Tsushima, Y; Uehara, T; Watanabe, S; Yamaguchi, A1
Arano, Y; Hanaoka, H; Higuchi, T; Ishioka, NS; Ohshima, Y; Suzuki, H; Tsushima, Y; Yamaguchi, A1
Bucher, CB; Heimgartner, H; Linden, A1

Reviews

2 review(s) available for phenylalanine and alpha-methylphenylalanine

ArticleYear
Adverse effects of excessive consumption of amino acids.
    Annual review of nutrition, 1984, Volume: 4

    Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Brain; Cattle; Diet; Disease Models, Animal; Ethionine; Fenclonine; Glycine; Growth Disorders; Histidine; Humans; Methionine; Nerve Tissue Proteins; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pneumonia, Atypical Interstitial, of Cattle; Serine; Stereoisomerism; Sulfhydryl Compounds; Tissue Distribution; Tryptophan; Tyrosine; Vitamin A

1984
Progress in experimental phenylketonuria: a critical review.
    Neuroscience and biobehavioral reviews, 1981,Spring, Volume: 5, Issue:1

    Topics: Abnormalities, Multiple; Animals; Disease Models, Animal; Energy Metabolism; Female; Fenclonine; Glutamates; Humans; Mice; Myelin Sheath; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Protein Biosynthesis; Pyridoxine; Serotonin

1981

Other Studies

39 other study(ies) available for phenylalanine and alpha-methylphenylalanine

ArticleYear
Transport and signaling via the amino acid binding site of the yeast Gap1 amino acid transceptor.
    Nature chemical biology, 2009, Volume: 5, Issue:1

    Topics: Amino Acid Transport Systems; Amino Acids; Biological Transport; Catalytic Domain; Dipeptides; Gene Expression Regulation, Fungal; Mutagenesis; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction

2009
Comparison of alpha-methylphenylalanine and p-chlorophenylalanine as inducers of chronic hyperphenylalaninaemia in developing rats.
    The Biochemical journal, 1978, Mar-15, Volume: 170, Issue:3

    Topics: Animals; Brain; Fenclonine; Liver; Metabolic Diseases; Methyltyrosines; Phenylalanine; Phenylalanine Hydroxylase; Rats; Tyrosine

1978
Isoenzyme composition of hepatic phenylalanine hydroxylase in developing rats after treatment with cortisol, alpha-methylphenylalanine and p-chlorophenylalanine in vivo.
    Biochemical medicine, 1978, Volume: 20, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Fenclonine; Fetus; Hydrocortisone; Isoenzymes; Liver; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats

1978
Postnatal alpha-methylphenylalanine treatment effects on adult mouse locomotor activity and avoidance learning.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:5

    Topics: Animals; Animals, Newborn; Avoidance Learning; Body Weight; Male; Mice; Motor Activity; Phenylalanine; Time Factors

1979
Alpha-methylphenylalanine, a new inducer of chronic hyperphenylalaninemia in sucling rats.
    Science (New York, N.Y.), 1976, Jun-04, Volume: 192, Issue:4243

    Topics: Amino Acids; Animals; Animals, Newborn; Disease Models, Animal; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats

1976
Diminished concentration of the NF-H subunit of neurofilaments in cerebral cortex of rats chronically treated with proline, methylmalonate and phenylalanine plus alpha-methylphenylalanine.
    Journal of inherited metabolic disease, 1992, Volume: 15, Issue:2

    Topics: Animals; Body Weight; Brain; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Methylmalonic Acid; Neurofilament Proteins; Organ Size; Phenylalanine; Proline; Rats; Rats, Inbred Strains

1992
Effect of phenylalanine, p-chlorophenylalanine and alpha-methylphenylalanine on glucose uptake in vitro by the brain of young rats.
    Biochemical Society transactions, 1990, Volume: 18, Issue:3

    Topics: Age Factors; Animals; Brain; Fenclonine; Glucose; In Vitro Techniques; Phenylalanine; Rats; Rats, Inbred Strains

1990
Cerebral serotonin regulation by phenylalanine analogues and during hyperphenylalaninemia.
    Biochemical pharmacology, 1987, Mar-15, Volume: 36, Issue:6

    Topics: Animals; Brain; Fenclonine; Hydroxyindoleacetic Acid; Phenylalanine; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase

1987
Effect of experimental hyperphenylalaninemia induced by dietary phenylalanine plus alpha-methylphenylalanine administration on amino acid concentration in neonatal chick brain, plasma, and liver.
    Neurochemical research, 1988, Volume: 13, Issue:6

    Topics: Amino Acids; Animals; Animals, Newborn; Brain; Chickens; Diet; Liver; Male; Phenylalanine

1988
Inhibition of brain and liver 3-hydroxy-3-methylglutaryl-CoA reductase and mevalonate-5-pyrophosphate decarboxylase in experimental hyperphenylalaninemia.
    Neurochemical research, 1988, Volume: 13, Issue:6

    Topics: Acyl Coenzyme A; Animals; Animals, Newborn; Body Weight; Brain; Carboxy-Lyases; Chickens; Diet; Liver; Male; Organ Size; Phenylalanine; Tyrosine

1988
Effect of hyperphenylalaninemia induced during suckling on brain DNA metabolism in rat pups.
    Neurochemical research, 1984, Volume: 9, Issue:4

    Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain; Cell Division; Disease Models, Animal; DNA; DNA Replication; Fenclonine; Kinetics; Phenylalanine; Rats; Rats, Inbred Strains

1984
Characterization of experimental phenylketonuria. Augmentation of hyperphenylalaninemia with alpha-methylphenylalanine and p-chlorophenylalanine.
    Biochimica et biophysica acta, 1980, Jan-17, Volume: 627, Issue:2

    Topics: Age Factors; Amino Acids; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Disease Models, Animal; Fenclonine; Humans; Learning; Myelin Proteins; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Rats

1980
Phenylketonuria: clinical and experimental considerations revealed by the use of animal models.
    Die Naturwissenschaften, 1980, Volume: 67, Issue:5

    Topics: Animals; Brain; Cerebellum; Disease Models, Animal; Fenclonine; Humans; Male; Neurons; Phenylalanine; Phenylketonurias; Rats

1980
PKU, learning, and models of mental retardation.
    Developmental psychobiology, 1984, Volume: 17, Issue:2

    Topics: Animals; Body Weight; Disease Models, Animal; Humans; Intellectual Disability; Learning; Phenylalanine; Phenylketonurias; Psychological Tests; Rats

1984
Developmental changes of cerebral phenylalanine uptake from severely elevated blood levels.
    Neurochemical research, 1984, Volume: 9, Issue:6

    Topics: Age Factors; Animals; Brain; Brain Chemistry; Humans; Phenylalanine; Phenylketonurias; Rats; Rats, Inbred F344

1984
The effects of (+)-amphetamine, alpha-methyltyrosine, and alpha-methylphenylalanine on the concentrations of m-tyramine and alpha-methyl-m-tyramine in rat striatum.
    British journal of pharmacology, 1983, Volume: 80, Issue:2

    Topics: alpha-Methyltyrosine; Amphetamine; Amphetamines; Animals; Corpus Striatum; Male; Methyltyrosines; p-Hydroxyamphetamine; Phenylalanine; Rats; Tyramine

1983
Use of alpha-methylphenylalanine for studies of brain development in experimental phenylketonuria.
    Journal of inherited metabolic disease, 1981, Volume: 4, Issue:2

    Topics: Animals; Brain; Cell Division; Cell Survival; Cerebellum; Disease Models, Animal; Humans; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats

1981
The effects of chronic hyperphenylalaninaemia on mouse brain protein synthesis can be prevented by other amino acids.
    The Biochemical journal, 1982, Aug-15, Volume: 206, Issue:2

    Topics: Amino Acids; Animals; Brain; Centrifugation, Density Gradient; Mice; Peptide Chain Elongation, Translational; Phenylalanine; Protein Biosynthesis; Ribosomes

1982
Modulation of cerebral catecholamine concentrations during hyperphenylalaninaemia.
    The Biochemical journal, 1982, Dec-15, Volume: 208, Issue:3

    Topics: Animals; Brain; Dopamine; Female; Kinetics; Male; Norepinephrine; Phenylalanine; Rats; Tyrosine

1982
The effects of hyperphenylalaninemia on fetal development: a new animal model of maternal phenylketonuria.
    Pediatric research, 1982, Volume: 16, Issue:5

    Topics: Animals; Brain; Diet; Female; Fetus; Growth; Humans; Liver; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred F344

1982
Effect of alpha-methylphenylalanine and phenylalanine on brain polyribosomes and protein synthesis.
    Journal of neurochemistry, 1981, Volume: 36, Issue:4

    Topics: Animals; Brain; Centrifugation, Density Gradient; Mice; Nerve Tissue Proteins; Peptide Chain Elongation, Translational; Phenylalanine; Phenylalanine Hydroxylase; Polyribosomes; Tyrosine

1981
Effects of alpha-methylphenylalanine plus phenylalanine treatment during development on myelin in rat brain.
    Neurochemical research, 1980, Volume: 5, Issue:7

    Topics: Age Factors; Animals; Dose-Response Relationship, Drug; Fatty Acids; Myelin Sheath; Organ Size; Phenylalanine; Rats; Sulfoglycosphingolipids; Synaptosomes

1980
Retarded development of neurons and oligodendroglia in rat forebrain produced by hyperphenylalaninemia results in permanent deficits in myelin despite long recovery periods.
    Experimental neurology, 1993, Volume: 124, Issue:2

    Topics: Animals; Animals, Newborn; Axons; Corpus Callosum; Disease Models, Animal; Female; Male; Molecular Weight; Myelin Basic Protein; Myelin Sheath; Neurofilament Proteins; Neurons; Oligodendroglia; Phenylalanine; Phenylketonurias; Prosencephalon; Rats; Rats, Sprague-Dawley

1993
An animal model of early-treated PKU.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:5 Pt 2

    Topics: Animals; Animals, Newborn; Behavior, Animal; Disease Models, Animal; Drug Therapy, Combination; Fetus; Homovanillic Acid; Hydroxyindoleacetic Acid; Injections; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Rats; Rats, Inbred Strains; Time Factors

1994
Effect of phenylalanine and alpha-methylphenylalanine on in vitro incorporation of 32P into cytoskeletal cerebral proteins.
    Neurochemistry international, 1995, Volume: 26, Issue:4

    Topics: Animals; Cerebral Cortex; Cytoskeletal Proteins; In Vitro Techniques; Nerve Tissue Proteins; Phenylalanine; Phosphorus Radioisotopes; Rats; Rats, Wistar

1995
Effect of phenylalanine and its metabolites on ATP diphosphohydrolase activity in synaptosomes from rat cerebral cortex.
    Neurochemical research, 1994, Volume: 19, Issue:9

    Topics: Animals; Apyrase; Cerebral Cortex; Disease Models, Animal; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Rats, Wistar; Synaptosomes

1994
Partial purification of a cyanobacterial membrane protein with amino terminal sequence similarity to the N-methylphenylalanine pilins.
    Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1994, Volume: 48, Issue:7

    Topics: Amino Acid Sequence; Bacterial Proteins; Cell Fractionation; Cyanobacteria; Fimbriae, Bacterial; Membrane Proteins; Molecular Sequence Data; Phenylalanine; Solubility

1994
Kinin B1 receptor antagonists containing alpha-methyl-L-phenylalanine: in vitro and in vivo antagonistic activities.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:3

    Topics: Animals; Blood Pressure; Bradykinin; Humans; Kallidin; Peptides; Peptidyl-Dipeptidase A; Phenylalanine; Plasma; Rabbits; Receptors, Neurokinin-3; Time Factors

1999
Effects of dietary mixtures of amino acids on fetal growth and maternal and fetal amino acid pools in experimental maternal phenylketonuria.
    The American journal of clinical nutrition, 1999, Volume: 69, Issue:4

    Topics: Amino Acids, Branched-Chain; Animals; Body Weight; Brain; Brain Chemistry; Diet; Embryonic and Fetal Development; Female; Maternal-Fetal Exchange; Phenylalanine; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats; Rats, Long-Evans

1999
Alanine prevents the decrease of Na+,K+-ATPase activity in experimental phenylketonuria.
    Metabolic brain disease, 1999, Volume: 14, Issue:2

    Topics: Alanine; Animals; Animals, Newborn; Cerebral Cortex; Injections, Subcutaneous; Phenylalanine; Phenylketonurias; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

1999
Experimental hyperphenylalaninemia provokes oxidative stress in rat brain.
    Biochimica et biophysica acta, 2002, Apr-24, Volume: 1586, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Catalase; Glutathione Peroxidase; Luminescent Measurements; Oxidative Stress; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Rats; Rats, Wistar; Superoxide Dismutase

2002
Brain catecholamines and human sleep.
    Nature, 1971, Sep-03, Volume: 233, Issue:5314

    Topics: alpha-Methyltyrosine; Catecholamines; Female; Humans; Male; Phenylalanine; Reproducibility of Results; Serotonin; Sleep; Sleep, REM

1971
Hyperphenylalaninemia reduces creatine kinase activity in the cerebral cortex of rats.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2003, Volume: 21, Issue:2

    Topics: Animals; Cerebral Cortex; Creatine Kinase; Enzyme Inhibitors; In Vitro Techniques; Phenylalanine; Phenylketonurias; Rats; Rats, Wistar

2003
Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.
    Journal of medicinal chemistry, 2005, Feb-10, Volume: 48, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Binding Sites; Cyclization; GRB2 Adaptor Protein; Models, Molecular; Molecular Conformation; Molecular Mimicry; Organophosphonates; Phenylalanine; Phosphopeptides; Phosphotyrosine; Protein Binding; src Homology Domains; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

2005
Allyl cyanate-to-isocyanate rearrangement for the synthesis of quaternary stereocenter with nitrogen substituent.
    Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:5

    Topics: Allyl Compounds; Cyanates; Isocyanates; Models, Chemical; Molecular Conformation; Molecular Structure; Phenylalanine; Stereoisomerism

2005
Mechanistic studies on the chiral recognition of polysaccharide-based chiral stationary phases using liquid chromatography and vibrational circular dichroism: reversal of elution order of N-substituted alpha-methyl phenylalanine esters.
    Journal of chromatography. A, 2009, May-01, Volume: 1216, Issue:18

    Topics: Chromatography, Liquid; Circular Dichroism; Esters; Phenylalanine; Polysaccharides

2009
Development of a Widely Usable Amino Acid Tracer: ⁷⁶Br-α-Methyl-Phenylalanine for Tumor PET Imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:5

    Topics: Adenocarcinoma; Animals; Bromine Radioisotopes; Cell Line, Tumor; Colonic Neoplasms; Drug Discovery; Humans; Mice; Phenylalanine; Positron-Emission Tomography; Tissue Distribution

2015
Novel
    Molecular pharmaceutics, 2019, 08-05, Volume: 16, Issue:8

    Topics: Animals; Cell Line, Tumor; Diagnosis, Differential; Fluorine Radioisotopes; Humans; Injections, Intravenous; Large Neutral Amino Acid-Transporter 1; Male; Mice; Neoplasms; Phenylalanine; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Xenograft Model Antitumor Assays

2019
Synthesis and Solid State Conformation of Tetrapeptide Amides Containing two Aib and two (αMe)Phe Residues - Use of Enantiomerically Pure 2-Benzyl-2-methyl-2H-azirin-3-amines as (αMe)Phe-Synthons.
    Chemistry & biodiversity, 2020, Volume: 17, Issue:7

    Topics: Amides; Aminoisobutyric Acids; Crystallography, X-Ray; Models, Molecular; Molecular Conformation; Oligopeptides; Phenylalanine; Stereoisomerism

2020