phenylalanine has been researched along with 7,8-dihydrobiopterin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bettoni, O; Bieri, J; Curtius, HC; Niederwieser, A; Schaub, J; Schircks, B; Viscontini, M | 1 |
| Bartholomé, K; Bieri, JH; Curtius, HC; Däumling, S; Niederwieser, A; Schaub, J; Schircks, B; Viscontini, M | 1 |
| Blaskovics, M; Blau, N; Curtius, HC; Giudici, T; Kierat, L | 1 |
| Appleman, JR; Beard, WA; Blakley, RL; Delcamp, TJ; Freisheim, JH; Prendergast, NJ; Tsay, JT | 1 |
| Døskeland, AP; Døskeland, SO; Flatmark, T; Haavik, J | 1 |
| Miyatake, T; Nakano, R; Ohwada, M; Tanaka, K; Yoneda, M | 1 |
| Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A | 1 |
| Fukuda, K; Hyodo, S; Kobayashi, Y; Tanaka, T; Usui, T | 1 |
| Aziz, AA; Blair, JA; Leeming, RJ; Sylvester, PE | 1 |
| Harpey, JP | 1 |
| Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS | 1 |
| Dhondt, JL; Farriaux, JP; Largilliere, C; Leeming, RJ; Leroux, B | 1 |
| Barford, PA; Blair, JA; Leeming, RJ; Smith, I | 1 |
| Hase, Y; Iwai, K; Kobashi, M; Oura, T; Shintaku, H; Turuhara, T | 1 |
| Clow, CL; Scriver, CR | 1 |
| Curtius, HC; Ghisla, S; Heizmann, CW; Köster, S; Macheroux, P; Pfleiderer, W; Thöny, B | 1 |
| Gray, DW; Shiman, R; Xia, T | 1 |
| Goodwill, KE; Sabatier, C; Stevens, RC | 1 |
| Bjørgo, E; Erlandsen, H; Flatmark, T; Stevens, RC | 1 |
| Frøystein, NA; Haavik, J; Knappskog, PM; Martínez, A; McKinney, J; Salaün, C; Teigen, K | 1 |
| Green, A; Hall, K; Leeming, R; Lucock, M; MacDonald, A; Rylance, G; Yates, Z | 1 |
| Hatakeyama, K; Haynes, TE; Meininger, CJ; Shi, W; Wu, G | 1 |
2 review(s) available for phenylalanine and 7,8-dihydrobiopterin
| Article | Year |
|---|---|
Phenylketonuria and other phenylalanine hydroxylation mutants in man.
Topics: Alleles; Amino Acid Metabolism, Inborn Errors; Animals; Biopterins; Dihydropteridine Reductase; Female; Fetal Diseases; Gene Frequency; Genetic Carrier Screening; Heterozygote; Humans; Hydroxylation; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Pregnancy; Pregnancy Complications; Rats | 1980 |
Regulation of tetrahydrobiopterin synthesis and bioavailability in endothelial cells.
Topics: Animals; Biopterins; Cytokines; Endothelial Cells; Estrogens; Gene Expression Regulation; Glucocorticoids; GTP Cyclohydrolase; Humans; Hydrogen-Ion Concentration; Models, Biological; Nitric Oxide; Oxygen; Phenylalanine | 2004 |
20 other study(ies) available for phenylalanine and 7,8-dihydrobiopterin
| Article | Year |
|---|---|
Atypical phenylketonuria caused by 7, 8-dihydrobiopterin synthetase deficiency.
Topics: Alcohol Oxidoreductases; Biopterins; Child, Preschool; Female; Guanosine Triphosphate; Humans; Phenylalanine; Phenylketonurias; Pteridines; Pterins | 1979 |
Tetrahydrobiopterin therapy of atypical phenylketonuria due to defective dihydrobiopterin biosynthesis.
Topics: Biopterins; Female; Humans; Infant; Phenylalanine; Phenylketonurias; Pteridines | 1978 |
Hyperphenylalaninaemia presumably due to carbinolamine dehydratase deficiency: loading tests with pterin derivatives.
Topics: Biopterins; Female; Humans; Hydro-Lyases; Infant, Newborn; Kinetics; Phenylalanine; Pteridines; Pterins | 1992 |
Kinetic investigation of the functional role of phenylalanine-31 of recombinant human dihydrofolate reductase.
Topics: Bacterial Proteins; Binding Sites; Biopterins; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Phenylalanine; Recombinant Proteins; Tetrahydrofolate Dehydrogenase; Tetrahydrofolates | 1990 |
Modulation by pterins of the phosphorylation and phenylalanine activation of phenylalanine 4-mono-oxygenase.
Topics: Binding Sites; Biopterins; Cyclic AMP; Enzyme Activation; Hydroxylation; Kinetics; Phenylalanine; Phenylalanine Hydroxylase; Phosphorylation; Protein Conformation | 1987 |
[A case of impaired dihydrobiopterin synthesis with marked diurnal fluctuation].
Topics: Adult; Biopterins; Circadian Rhythm; Humans; Intellectual Disability; Male; Movement Disorders; Phenylalanine; Phenylketonurias | 1986 |
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1985 |
Hyperphenylalaninaemia due to impaired dihydrobiopterin biosynthesis: leukocyte function and effect of tetrahydrobiopterin therapy.
Topics: Amino Acid Metabolism, Inborn Errors; Biopterins; Child; Child, Preschool; Female; Humans; Leukocytes; Male; Phenylalanine | 1985 |
Tetrahydrobiopterin metabolism in Down's syndrome and in non-Down's syndrome mental retardation.
Topics: Adult; Aged; Biopterins; Down Syndrome; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenylalanine; Pteridines | 1982 |
[Biopterin synthesis defects: complete deficiencies (reductase and synthetase)].
Topics: Alcohol Oxidoreductases; Biopsy, Needle; Biopterins; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Liver; Phenylalanine; Phenylketonurias; Pteridines; Pterins | 1983 |
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines | 1983 |
Dihydrobiopterin biosynthesis deficiency.
Topics: Biopterins; Female; Humans; Infant; Infant, Newborn; Metabolism, Inborn Errors; Neopterin; Phenylalanine; Pteridines | 1983 |
Blood spots on Guthrie cards can be used for inherited tetrahydrobiopterin deficiency screening in hyperphenylalaninaemic infants.
Topics: Adolescent; Adult; Biopterins; Child; Child, Preschool; Dihydropteridine Reductase; Humans; Infant, Newborn; Methods; Phenylalanine; Phenylketonurias; Pteridines; Specimen Handling | 1984 |
A case of tetrahydrobiopterin deficiency due to a defective synthesis of dihydrobiopterin.
Topics: Biopterins; Humans; Infant; Male; Phenylalanine; Pteridines | 1982 |
Human pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor-1 alpha. Characterization and kinetic analysis of wild-type and mutant enzymes.
Topics: Base Sequence; Biopterins; Catalysis; Cysteine; Humans; Hydro-Lyases; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Liver; Molecular Sequence Data; Mutagenesis; Phenylalanine; Phenylalanine Hydroxylase; Protein Binding; Pterins; Recombinant Proteins; Spectrometry, Fluorescence; Temperature; Transcription Factors; Ultraviolet Rays | 1995 |
Regulation of rat liver phenylalanine hydroxylase. III. Control of catalysis by (6R)-tetrahydrobiopterin and phenylalanine.
Topics: Animals; Biopterins; Enzyme Activation; Liver; Phenylalanine; Phenylalanine Hydroxylase; Rats; Rats, Sprague-Dawley | 1994 |
Crystal structure of tyrosine hydroxylase with bound cofactor analogue and iron at 2.3 A resolution: self-hydroxylation of Phe300 and the pterin-binding site.
Topics: Animals; Binding Sites; Biopterins; Coenzymes; Crystallization; Crystallography, X-Ray; Humans; Hydroxylation; Iron; Models, Molecular; Mutagenesis, Site-Directed; Phenylalanine; Rats; Spectroscopy, Mossbauer; Substrate Specificity; Tyrosine 3-Monooxygenase; X-Rays | 1998 |
Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Topics: Binding Sites; Biopterins; Catalysis; Catecholamines; Crystallography, X-Ray; Dimerization; Humans; Mutagenesis, Site-Directed; Phenylalanine; Phenylalanine Hydroxylase; Pterins | 2000 |
Conformation of the substrate and pterin cofactor bound to human tryptophan hydroxylase. Important role of Phe313 in substrate specificity.
Topics: Binding Sites; Biopterins; Humans; Iron; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Phenylalanine; Protein Binding; Protein Conformation; Protons; Recombinant Proteins; Substrate Specificity; Thermodynamics; Tryptophan; Tryptophan Hydroxylase | 2001 |
The impact of phenylketonuria on folate metabolism.
Topics: Biopterins; Chromatography, High Pressure Liquid; Coenzymes; Folic Acid; Homocysteine; Humans; Immunoassay; Phenylalanine; Phenylketonurias | 2002 |