phenylalanine and 5-hydroxytryptophan

phenylalanine has been researched along with 5-hydroxytryptophan in 109 studies

Research

Studies (109)

TimeframeStudies, this research(%)All Research%
pre-199094 (86.24)18.7374
1990's2 (1.83)18.2507
2000's8 (7.34)29.6817
2010's4 (3.67)24.3611
2020's1 (0.92)2.80

Authors

AuthorsStudies
Butler, IJ; Holtzman, NA; Kaufman, S; Koslow, SH; Krumholz, A1
Airaksinen, MM; MacDonald, EJ; Marvola, M; Turakka, H1
Sakurada, S1
Wirz-Justice, A1
Carlsson, A; Lindqvist, M2
Abroms, IF; Breslow, JL; Brewster, TG; Kaufman, S; Milstien, S; Moskowitz, MA1
Bautz, G; Dairman, W; Horst, WD; Marchelle, ME1
Faller, DV; Fernstrom, JD; Shabshelowitz, H1
Glassgold, JM; Hauser, DC; Levandowsky, M1
McKean, CM; Schafer, EW1
Biasetti, S; Bracco, G; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A1
Spector, AA; Strom, DK; Yorek, MA1
Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K1
Pulmones, MT; Sansaricq, C; Snyderman, SE1
Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A1
Engelman, K; Fram, DH; Kupfer, DJ; Sjoerdsma, A; Snyder, F; Wyatt, RJ1
Dement, WC; Engelman, K; Sjoerdsma, A; Snyder, F; Wyatt, RJ; Zarcone, V1
Guano, G; Guilbaud, G; Menetrey, D1
Bert, J1
Korf, J; Postema, F; Venema, K1
Kido, R; Minatogawa, Y; Noguchi, T1
Kido, R; Nakamura, J; Noguchi, T1
Agarwal, MK1
Corgier, M; Pacheco, H; Tappaz, M1
Birkmayer, W1
Murali, DK; Radhakrishnan, AN1
von Studnitz, W; Waldenström, J1
Cheney, DL; Goldstein, A1
Campbell, BA; Fibiger, HC1
Geller, I; Hartmann, RJ1
Buguet, A; Froment, JL; Jones, B; Jouvet, M; Pujol, JF1
Ito, A; Schanberg, SM1
Azbekyan, SG; Lapin, IP; Oxenkrug, GF1
Hole, K1
Kilbey, MM; Nance, DM1
Dickens, G; Guroff, G; Letendre, CH1
Putkonen, PT1
Boggan, WO; Freedman, DX; Schlesinger, K1
Wyatt, RJ1
Boullin, DJ1
Brissaud, HE; Costil, J; Galli, J; Richardet, JM1
Prakh'e, IB1
Neuhoff, V; Osborne, NN1
Bensinger, RE; Klein, DC; Lovenberg, W; Weller, JL1
Loo, YH1
Behbehani, AW; Neuhoff, V; Quentin, CD; Schulte, FJ1
Davis, P; Juhl, R; Rosazza, JP1
Simpson, LL1
Aronson, RB; Cotzias, GC; Gellene, R; Papavasiliou, PS1
Grahame-Smith, DG1
Camba, R; Di Chiara, G; Spano, PF1
Hsia, DY1
Christenson, JG; Dairman, W; Udenfriend, S1
Görisch, H; Lingens, F1
Glick, D; Hosoda, S1
Van der Hoeven, T; Woolley, DW1
Koe, BK; Weissman, A1
De Ropp, RS; Furst, A1
Geller, E; Yuwiler, A1
Agathopoulos, A; Bafataki, M; Danelatou-Athanassiadou, C; Nicolopoulos, D1
Brown, RM; Lal, H1
Jouvet, M1
Gabay, S; Huang, KH1
Oja, SS1
Volicer, L1
Rosen, AJ1
Kadzielawa, K; Widy-Tyszkiewicz, E1
Brodie, BB; Gessa, GL; Tagliamonte, A; Tagliamonte, P1
Tammisto, T; Ylitalo, P1
Bruinvels, J; Kemper, GC1
Shillito, EE2
Eidelberg, E; Schwartz, AS1
Brodie, BB; Gessa, GL; Tagliamonte, A1
Gál, EM; Millard, SA; Roggeveen, AE1
Sanders-Bush, E; Sulser, F1
Hoyland, VJ; Shillito, EE; Vogt, M1
Kerkut, GA; Ralph, KL; Walker, RJ; Woodruff, GN1
Blum, JJ; Brizzi, G1
Chan, YL; Huang, KC1
Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS1
Hüther, G; Lane, JD; Neuhoff, V; Piel, N1
Blau, N; Dhondt, JL1
Dhondt, JL; Mikaeloff, Y; Pinton, F; Ponsot, G; Sevin, C1
Meyers, S1
Chiang, SC; Chien, YH; Chiu, YN; Chou, SP; Chu, SY; Huang, A; Hwu, WL; Lin, JM; Wang, TR1
Cai, YF; Chai, SH; Gao, LH; Liu, HL; Liu, LL; Wu, YT1
BOSE, BC; SAIFI, AQ; SHARMA, SK; VIJAYVARGIYA, R1
BRENCHLEY, Y; HSIA, DY; NISHIMURA, K1
FONNUM, F; HAAVALDSEN, R; TANGEN, O1
VANDERHOEVEN, T; WOOLLEY, DW1
JACOBY, GA; LADU, BN1
BRODY, KR; LUTTERS, BM; SPENCER, RP1
CARVER, MJ; COPENHAVER, JH; SCHAIN, RJ1
HSIA, DY; JUSTICE, P1
GELLER, E; SLATER, GG; YUWILER, A1
HANSEN, S; LING, GM; MACDOUGALL, L; PERRY, TL1
Chien, YH; Hwu, WL; Liu, HM; Peng, SS; Tseng, WY1
Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ1
Cheng, LY; Chiu, PC; Hsiao, KJ; Lee, NC; Liu, TT; Niu, DM1
Chang, M; Fu, GX; He, C; Hsiao, KJ; Li, XW; Liu, TT; Shen, M; Shen, S; Wang, L; Yu, WM; Zhao, SP1
Andolina, D; Cabib, S; Conversi, D; Latagliata, C; Mela, IL; Pascucci, T; Puglisi-Allegra, S; Ventura, R1
Boben-Bardutzky, D; Hafner, M; Ihan, A; Jukić, T; Rojc, B1
Budac, D; du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C; Smagin, G; Song, D1
Cao, Z; Han, B; Liu, Y; Zhu, W; Zou, H1
Bączek, T; Konieczna, L; Niedźwiecki, M; Roszkowska, A1
Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA1

Reviews

5 review(s) available for phenylalanine and 5-hydroxytryptophan

ArticleYear
Pharmacology of the carcinoid syndrome.
    Lancet (London, England), 1968, Feb-24, Volume: 1, Issue:7539

    Topics: 5-Hydroxytryptophan; Bradykinin; Diarrhea; Drug Synergism; Humans; Kinins; Malignant Carcinoid Syndrome; Methysergide; Neurologic Manifestations; Phenylalanine; Prostaglandins; Serotonin; Serotonin Antagonists; Skin Manifestations

1968
Monoamines and the regulation of vigilance and sleep.
    Medical biology, 1974, Volume: 52, Issue:3

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Blood-Brain Barrier; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopa Decarboxylase; Haplorhini; Humans; Muscle Tonus; Norepinephrine; Papio; Phenylalanine; Rats; Reserpine; Serotonin; Sleep Stages; Sleep, REM; Stimulation, Chemical; Tryptophan; Wakefulness

1974
Progress report: the carcinoid syndrome.
    Gut, 1970, Volume: 11, Issue:2

    Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydroxyindoleacetic Acid; Kallikreins; Liver Neoplasms; Malignant Carcinoid Syndrome; Methyldopa; Methysergide; Neoplasm Metastasis; Phenoxybenzamine; Phenylalanine; Serotonin

1970
Biochemical factors in mental retardation.
    Proceedings of the annual meeting of the American Psychopathological Association, 1967, Volume: 56

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Diet Therapy; Female; Guinea Pigs; Haplorhini; Humans; Infant; Intellectual Disability; Intelligence Tests; Male; Metabolism, Inborn Errors; Monoamine Oxidase; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan; Tyrosine

1967
Use of neurotransmitter precursors for treatment of depression.
    Alternative medicine review : a journal of clinical therapeutic, 2000, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Depression; Humans; Phenylalanine; Tryptophan; Tyrosine

2000

Trials

6 trial(s) available for phenylalanine and 5-hydroxytryptophan

ArticleYear
[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
    No to hattatsu = Brain and development, 1989, Volume: 21, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan

1989
Effects of L-tryptophan (a natural sedative) on human sleep.
    Lancet (London, England), 1970, Oct-24, Volume: 2, Issue:7678

    Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aged; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylalanine; Placebos; Serotonin; Sex Factors; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Tryptophan

1970
Effects of 5-hydroxytryptophan on the sleep of normal human subjects.
    Electroencephalography and clinical neurophysiology, 1971, Volume: 30, Issue:6

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Animals; Brain; Cats; Electroencephalography; Electromyography; Electrooculography; Female; Humans; Hydroxyindoleacetic Acid; Male; Phenylalanine; Placebos; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM

1971
The serotonin-catecholamine-dream bicycle: a clinical study.
    Biological psychiatry, 1972, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Aged; Brain; Brain Chemistry; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Electroencephalography; Female; Fenclonine; Humans; Male; Mental Disorders; Middle Aged; Monoamine Oxidase Inhibitors; Phenylalanine; Serotonin; Sleep; Sleep, REM; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase

1972
Parkinsonism and DOPA.
    Transactions of the Association of American Physicians, 1968, Volume: 81

    Topics: 5-Hydroxytryptophan; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Humans; Male; Manganese Poisoning; Mining; Occupational Diseases; Parkinson Disease; Phenylacetates; Phenylalanine; Placebos

1968
The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms.
    Collegium antropologicum, 2011, Volume: 35, Issue:4

    Topics: 5-Hydroxytryptophan; Alcoholism; Bilirubin; CD4-Positive T-Lymphocytes; Dietary Supplements; Double-Blind Method; Glutamine; Humans; Hydrocortisone; Phenylalanine; Prospective Studies; Substance Withdrawal Syndrome

2011

Other Studies

98 other study(ies) available for phenylalanine and 5-hydroxytryptophan

ArticleYear
A disorder of biogenic amines in dihydropteridine reductase deficiency.
    Annals of neurology, 1978, Volume: 3, Issue:3

    Topics: 5-Hydroxytryptophan; Biogenic Amines; Brain; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Liver; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Vanilmandelic Acid

1978
Protective effect of tryptophan and 5-hydroxytryptophan on experimental phenylketonuria induced with phenylalanine+ p-cholorophenylalanine in rats.
    Medical biology, 1975, Volume: 53, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Body Weight; Brain; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Motor Activity; Norepinephrine; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan

1975
[Effects of beta-phenylethylamine derivatives on the central nervous system. (5) The effect of intracerebral administration of tyramine on head twitching in mice pre-treated with isocarboxazid].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1975, Volume: 71, Issue:8

    Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Brain; Drug Interactions; Fenclonine; Haloperidol; Head; Isocarboxazid; Male; Mice; Movement; Phenothiazines; Phenylalanine; Tyramine; Tyrosine

1975
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
    Neuropsychobiology, 1977, Volume: 3, Issue:4

    Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine

1977
Dependence of 5-HT and catecholamine synthesis on concentrations of precursor amino-acids in rat brain.
    Naunyn-Schmiedeberg's archives of pharmacology, 1978, Volume: 303, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Haloperidol; Isoleucine; Kinetics; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine

1978
Dihydropteridine reductase deficiency associated with severe neurologic disease and mild hyperphenylalaninemia.
    Pediatrics, 1979, Volume: 63, Issue:1

    Topics: 5-Hydroxytryptophan; Ascorbic Acid; Consanguinity; Dopamine; Humans; Infant; Levodopa; Liver; Male; NADH, NADPH Oxidoreductases; Nervous System Diseases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Serotonin

1979
The proportionate loss of L-3,4-dihydroxyphenylalanine and L-5-hydroxttryptophan decarboxylating activity in rat central nervous system following intracisternal administration of 5, 6-dihydroxytryptamine or 6-hydroxydopamine.
    Journal of neurochemistry, 1975, Volume: 24, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carboxy-Lyases; Cerebral Cortex; Hydroxydopamines; Norepinephrine; Phenylalanine; Rats; Serotonin; Spinal Cord

1975
Acute reduction of brain serotonin and 5-HIAA following food consumption: correlation with the ratio of serum tryptophan to the sum of competing amino acids.
    Journal of neural transmission, 1975, Volume: 36, Issue:2

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Diet; Hydroxyindoleacetic Acid; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine; Valine

1975
Ultrasensitive chemosensory responses by a protozoan to epinephrine and other neurochemicals.
    Science (New York, N.Y.), 1975, Oct-17, Volume: 190, Issue:4211

    Topics: 5-Hydroxytryptophan; Animals; Betaine; Carbachol; Chemoreceptor Cells; Chemotaxis; Choline; Dose-Response Relationship, Drug; Epinephrine; Eukaryota; Glutamates; Glycine; Norepinephrine; Phenylalanine; Putrescine; Serotonin; Taurine; Tryptophan

1975
Evidence that monoamines influence human evoked potentials.
    Brain research, 1975, Nov-28, Volume: 99, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Biogenic Amines; Dihydroxyphenylalanine; Evoked Potentials; Female; Humans; Male; Phenylalanine; Phenylketonurias; Reaction Time; Tyrosine; Visual Cortex; Visual Perception

1975
Neurotransmitter therapy and diet in malignant phenylketonuria.
    European journal of pediatrics, 1987, Volume: 146, Issue:1

    Topics: 5-Hydroxytryptophan; Carbidopa; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Levodopa; Phenylalanine; Phenylketonurias

1987
Synthesis and high affinity uptake of serotonin and dopamine by human Y79 retinoblastoma cells.
    Journal of neurochemistry, 1987, Volume: 49, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biological Transport; Cell Line; Dihydroxyphenylalanine; Dopamine; Eye Neoplasms; Humans; Hydroxyindoleacetic Acid; Kinetics; Norepinephrine; Phenylalanine; Retinoblastoma; Serotonin; Tryptophan; Tyrosine

1987
Successful long term therapy of biopterin deficiency.
    Journal of inherited metabolic disease, 1987, Volume: 10, Issue:3

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Dihydropteridine Reductase; Female; Humans; Infant, Newborn; Levodopa; Liver; Neopterin; Phenylalanine; Phenylalanine Hydroxylase

1987
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
    Israel journal of medical sciences, 1985, Volume: 21, Issue:6

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine

1985
[Cerebral monoamines and evoked activity in the centrum medianum of the thalamus and in the primary somatic cortical area].
    Electroencephalography and clinical neurophysiology, 1971, Volume: 31, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Amphetamine; Animals; Arousal; Brain Chemistry; Cats; Cerebral Cortex; Drug Synergism; Electric Stimulation; Evoked Potentials; Injections, Intraperitoneal; Methyldopa; Nialamide; Phenylalanine; Reserpine; Sleep Stages; Thalamus

1971
[Effect of p-chlorophenylalanine on sleep in the baboon Papio papio].
    Electroencephalography and clinical neurophysiology, 1972, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Fenclonine; Haplorhini; Papio; Phenylalanine; Serotonin; Sleep; Sleep Stages

1972
Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Autoanalysis; Brain; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Phenylalanine; Rats; Serotonin; Staining and Labeling; Stereotaxic Techniques; Time Factors

1974
Aromatic amino acid transaminases in rat brain.
    Journal of neurochemistry, 1973, Volume: 20, Issue:5

    Topics: 5-Hydroxytryptophan; Ammonium Sulfate; Animals; Brain; Chemical Precipitation; Chromatography, DEAE-Cellulose; Dihydroxyphenylalanine; Ketoglutaric Acids; Kynurenine; Male; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine Transaminase

1973
Aromatic amino acid transaminase in rat intestine.
    The Biochemical journal, 1973, Volume: 135, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, DEAE-Cellulose; Chromatography, Gel; Intestine, Small; Ketoglutaric Acids; Kinetics; Kynurenine; Male; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine Transaminase

1973
Interference by tryptophan analogues of an in vitro assay for liver tyrosine transaminase activity.
    FEBS letters, 1974, Mar-15, Volume: 40, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Colorimetry; Dihydroxyphenylalanine; Enzyme Activation; Kinetics; Leucine; Liver; Mice; Phenylalanine; Serotonin; Structure-Activity Relationship; Tryptophan; Tyrosine Transaminase

1974
[Partial purification and study of different properties of 5-hydroxy-tryptophan decarboxylase from rat brain].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1973, Feb-05, Volume: 276, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Dopa Decarboxylase; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methods; Phenylalanine; Pyridoxal Phosphate; Rats; Ultracentrifugation

1973
[Experimental findings and new aspects in extrapyramidal diseases].
    Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1966, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Monoamine Oxidase Inhibitors; Movement Disorders; Norepinephrine; Parkinson Disease; Perphenazine; Phenylalanine; Reserpine; Serotonin; Tyrosine

1966
Purification and properties of 5-hydroxytryptophan decarboxylase from monkey small intestine.
    Indian journal of biochemistry, 1970, Volume: 7, Issue:1

    Topics: 5-Hydroxytryptophan; Amines; Animals; Aspartic Acid; Benzoates; Carboxy-Lyases; Edetic Acid; Glutamates; Glutathione; Haplorhini; Histidine; Intestine, Small; Keto Acids; Kinetics; Male; Mercaptoethanol; Metals; Phenylalanine; Pyridoxal Phosphate; Tryptophan; Tyrosine

1970
[Pharmacological and therapeutic studies (p-chlorphenylalanin) on carcinoid syndrome in 11 cases].
    Klinische Wochenschrift, 1971, Jul-01, Volume: 49, Issue:13

    Topics: 5-Hydroxytryptophan; Aged; Blood Pressure; Bradykinin; Epinephrine; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Isoproterenol; Male; Malignant Carcinoid Syndrome; Metaraminol; Middle Aged; Mixed Function Oxygenases; Norepinephrine; Phentolamine; Phenylalanine; Serotonin; Tryptophan; Tyramine

1971
The effect of p-chlorophenylalanine on opiate-induced running, analgesia, tolerance and physical dependence in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:1

    Topics: 5-Hydroxytryptophan; Analgesia; Animals; Behavior, Animal; Brain Chemistry; Drug Tolerance; Fenclonine; Humans; Levorphanol; Male; Morphine Dependence; Phenylalanine; Rats; Serotonin; Tritium

1971
The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat.
    Neuropharmacology, 1971, Volume: 10, Issue:1

    Topics: 5-Hydroxytryptophan; Adaptation, Physiological; Animals; Behavior, Animal; Environment; Fenclonine; Locomotion; Phenylalanine

1971
P-Chlorophenylalanine effects on a conditioned emotional response in rats.
    Life sciences. Pt. 1: Physiology and pharmacology, 1971, Aug-15, Volume: 10, Issue:16

    Topics: 5-Hydroxytryptophan; Animals; Anxiety; Conditioning, Operant; Conditioning, Psychological; Electroshock; Fear; Fenclonine; Humans; Hunger; Male; Phenylalanine; Rats; Reward; Sound

1971
The central metabolism of serotonin in the cat during insomnia. A neurophysiological and biochemical study after administration of P-chlorophenylalanine or destruction of the Raphé system.
    Brain research, 1971, Jun-18, Volume: 29, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cats; Central Nervous System; Cerebral Cortex; Electroencephalography; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Phenylalanine; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Tritium

1971
Central nervous system mechanisms responsible for blood pressure elevation induced by p-chlorophenylalanine.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 181, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain Chemistry; Central Nervous System; Drug Interactions; Esters; Fenclonine; Histological Techniques; Injections; Male; Norepinephrine; Phentolamine; Phenylalanine; Propranolol; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereotaxic Techniques

1972
Involvement of brain serotonin in the stimulant action of amphetamine and of cholinolytics.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 197, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Atropine; Benactyzine; Brain; Brain Chemistry; Drug Antagonism; Drug Synergism; Female; Fenclonine; Locomotion; Lysergic Acid Diethylamide; Male; Methylcellulose; Methysergide; Mice; Motor Activity; Norepinephrine; Phenylalanine; Receptors, Drug; Serotonin; Serotonin Antagonists; Stimulation, Chemical

1972
Reduced 5-hydroxyindole synthesis reduces postnatal brain growth in rats.
    European journal of pharmacology, 1972, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Body Weight; Brain; Brain Chemistry; Drug Interactions; Female; Fenclonine; Hydroxylation; Indoles; Male; Nerve Tissue Proteins; Organ Size; Phenylalanine; Postpartum Period; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Time Factors

1972
Self-selection of 5-hydroxytryptophan in dl-para-chlorophenylalanine treated rats.
    Physiology & behavior, 1972, Volume: 8, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain Chemistry; Drinking Behavior; Fenclonine; Food Preferences; Male; Phenylalanine; Rats; Serotonin; Taste; Water

1972
The effect of L-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo.
    Journal of neural transmission, 1972, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Acetamides; Animals; Benzyl Compounds; Brain; Carboxy-Lyases; Dimethylamines; Dose-Response Relationship, Drug; Feedback; Female; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Mice; Nialamide; Phenylalanine; Reserpine; Sensory Receptor Cells; Serine; Serotonin; Tryptamines; Tryptophan; Tryptophan Hydroxylase; Tyrosine

1972
The tryptophan hydroxylase of Chromobacterium violaceum.
    The Journal of biological chemistry, 1974, Nov-25, Volume: 249, Issue:22

    Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Cell Division; Chromatography, DEAE-Cellulose; Chromatography, Paper; Chromobacterium; Enzyme Induction; Fenclonine; Hydrogen-Ion Concentration; Kinetics; Mixed Function Oxygenases; Oxidation-Reduction; Phenylalanine; Pteridines; Spectrometry, Fluorescence; Sulfhydryl Reagents; Time Factors; Tryptophan; Tryptophan Hydroxylase

1974
Genetics of audiogenic seizures. 3. Time response relationships between drug administration and seizure susceptibility.
    Life sciences. Pt. 1: Physiology and pharmacology, 1970, Jul-01, Volume: 9, Issue:13

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Brain; Brain Chemistry; Female; Hydrazines; Iproniazid; Male; Methyltyrosines; Mice; Norepinephrine; Phenylalanine; Reserpine; Seizures; Serotonin; Sound; Time Factors

1970
Platelet transaminase.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: 5-Hydroxytryptophan; Acetates; Amination; Amino Acids; Aminobutyrates; Aspartic Acid; Blood Platelets; Carbon Isotopes; Glutamates; Glycolates; Humans; Hydroxylamines; Kinetics; Leucine; Phenylalanine; Transaminases; Tyrosine

1972
[Urinary excretion of 5-hydroxyindoleacetic acid. II. In children with phenylketonuria, effects of 5-hydroxytryptophan].
    La Nouvelle presse medicale, 1973, Sep-15, Volume: 2, Issue:32

    Topics: 5-Hydroxytryptophan; Administration, Oral; Child, Preschool; Female; Humans; Hydroxyindoleacetic Acid; Infant; Injections, Intravenous; Intestinal Absorption; Male; Phenylalanine; Phenylketonurias

1973
[Effect of agents, changing the monoamine level, on audiogenic epileptic seizures in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1973, Volume: 76, Issue:9

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Brain; Depression, Chemical; Dihydroxyphenylalanine; Female; Male; Methyltyrosines; Methysergide; Nialamide; Norepinephrine; Phenylalanine; Rats; Reserpine; Seizures; Serotonin; Stimulation, Chemical

1973
In vitro experiments on the metabolism, accumulation and release of 5-HT in the nervous system of the snail Helix pomatia.
    Journal of neurochemistry, 1974, Volume: 22, Issue:3

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Biological Transport, Active; Calcium; Carbon Radioisotopes; Chromatography, Thin Layer; Desipramine; Electric Stimulation; Ganglia; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Isotope Labeling; Magnesium; Nerve Tissue; Ouabain; Phenylalanine; Serotonin; Snails; Sorbitol; Structure-Activity Relationship; Temperature; Time Factors; Tritium; Tryptophan

1974
Radiometric assay of total tryptophan hydroxylation by intact cultured pineal glands.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Chromatography, Ion Exchange; Cycloheximide; Evaluation Studies as Topic; Female; Isoproterenol; Kinetics; Male; Melatonin; Mescaline; Methods; Mixed Function Oxygenases; Organ Culture Techniques; Phenylalanine; Pineal Gland; Probenecid; Rats; Serotonin; Species Specificity; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase

1974
Serotonin deficiency in experimental hyperphenylalaninemia.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Biphenyl Compounds; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dopa Decarboxylase; Female; Humans; Hydroxyindoleacetic Acid; Oxazoles; Pargyline; Phenethylamines; Phenylalanine; Phenylketonurias; Pregnancy; Pyridoxal; Pyridoxamine; Pyridoxine; Rats; Serotonin; Spectrometry, Fluorescence; Time Factors; Tritium

1974
Microanalysis with 14-C-dansyl chloride of amino acids and amines in the cerebrospinal fluid of patients with phenylketonuria. II. Determination of 5-hydroxyindole derivatives after loading with L-phenylalanine.
    Neuropadiatrie, 1974, Volume: 5, Issue:3

    Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Autoradiography; Carbon Radioisotopes; Child; Child, Preschool; Dansyl Compounds; Humans; Hydroxyindoleacetic Acid; Hydroxylation; Infant; Methods; Microchemistry; Phenylalanine; Phenylketonurias; Serotonin

1974
Tryptophol formation by Zygosaccharomyces priorianus.
    Applied microbiology, 1973, Volume: 26, Issue:1

    Topics: 5-Hydroxytryptophan; Acetaldehyde; Amino Alcohols; Chromatography, Thin Layer; Fermentation; Fluorometry; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Phenylalanine; Pyruvates; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Stereoisomerism; Tryptamines; Tryptophan; Tyrosine

1973
The interaction between 5-hydroxytryptamine and botulinum toxin type A.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2

    Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Antitoxins; Botulism; Chlorine; Clostridium botulinum; Diaphragm; Female; Hydroxyindoleacetic Acid; In Vitro Techniques; Mice; Neuromuscular Junction; Norepinephrine; Pargyline; Phenylalanine; Phrenic Nerve; Rats; Serotonin; Toxins, Biological

1968
Evidence for inhibition by brain serotonin of mouse killing behaviour in rats.
    Nature, 1971, Sep-24, Volume: 233, Issue:5317

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Brain; Humans; Injections, Intraperitoneal; Limbic System; Male; Methylation; Mice; Pargyline; Phenylalanine; Rats; Serotonin; Serotonin Antagonists; Tyrosine

1971
Preparation and properties of a homogeneous aromatic L-amino acid decarboxylase from hog kidney.
    Archives of biochemistry and biophysics, 1970, Volume: 141, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbon Isotopes; Carboxy-Lyases; Chelating Agents; Chloromercuribenzoates; Chromatography, Ion Exchange; Copper; Dopa Decarboxylase; Electrophoresis, Disc; Ethylmaleimide; Female; Goats; Histidine; Hydrogen-Ion Concentration; Immunodiffusion; Iodoacetates; Kidney; Kinetics; Mercaptoethanol; Mercury; Methods; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Sulfhydryl Compounds; Swine; Tyrosine Decarboxylase; Ultracentrifugation; Zinc

1970
3-D-eoxy-D-arabino-heptulosonate-7-phosphate synthase of Streptomyces aureofaciens Tü 24. II. Repression and inhibition by tryptophan and tryptophan analogues.
    Biochimica et biophysica acta, 1971, Sep-22, Volume: 242, Issue:3

    Topics: 5-Hydroxytryptophan; Aldehyde-Lyases; Allosteric Regulation; Enzyme Repression; Hydrogen-Ion Concentration; Phenylalanine; Phosphoenolpyruvate; Stereoisomerism; Streptomyces; Streptomyces aureofaciens; Tetroses; Tryptophan; Tyrosine

1971
Studies in histochemistry. LXXIX. Properties of tryptophan hydroxylase from neoplastic murine mast cells.
    The Journal of biological chemistry, 1966, Jan-10, Volume: 241, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mast Cells; Mice; Mixed Function Oxygenases; Neoplasms; Phenylalanine; Serotonin; Tryptophan

1966
Serotonin deficiency in infancy as a cause of a mental defect in experimental phenylketonuria.
    International journal of neuropsychiatry, 1965, Volume: 1, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Chlorpromazine; Electroshock; Female; Humans; In Vitro Techniques; Intellectual Disability; Learning; Male; Melatonin; Mice; Neurosecretion; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Reserpine; Serotonin; Tryptamines; Tyrosine; Urine

1965
p-Chlorophenylalanine: a specific depletor of brain serotonin.
    The Journal of pharmacology and experimental therapeutics, 1966, Volume: 154, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dogs; Hydroxyindoleacetic Acid; Liver; Mice; Mixed Function Oxygenases; Pargyline; Phenethylamines; Phenylalanine; Rats; Reserpine; Serotonin; Tetrabenazine

1966
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
    Brain research, 1966, Volume: 2, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine

1966
Brain amine decrease in leucine-fed rats.
    Journal of neurochemistry, 1967, Volume: 14, Issue:7

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Animal Feed; Animals; Ascorbic Acid; Blood-Brain Barrier; Body Weight; Brain; Brain Chemistry; Carboxy-Lyases; Corticosterone; Diet; Dopamine; Female; Glutamates; Leucine; Liver; Male; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Organ Size; Oxygenases; Phenylalanine; Rats; Serotonin; Transaminases; Tryptophan; Tryptophan Oxygenase

1967
Urinary exeretion of phenolic and indolic compounds, metacatecholamines, and VMA by full-term and premature infants.
    Pediatrics, 1968, Volume: 41, Issue:4

    Topics: 5-Hydroxytryptophan; Benzoates; Catecholamines; Cinnamates; Creatinine; Humans; Indoleacetic Acids; Infant, Newborn; Infant, Premature; Kynurenine; Lactates; Mandelic Acids; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Phthalic Acids; Propionates; Tryptophan; Tyrosine

1968
A possible relationship between catecholamines and acute toxicity of desipramine.
    Psychopharmacologia, 1968, Volume: 12, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Male; Methyldopa; Mice; Mortality; Phenylalanine; Reserpine

1968
Insomnia and decrease of cerebral 5-hydroxytryptamine after destruction of the raphe system in the cat.
    Advances in pharmacology, 1968, Volume: 6, Issue:Pt B

    Topics: 5-Hydroxytryptophan; Animals; Brain; Cats; Norepinephrine; Phenylalanine; Serotonin; Sleep; Sleep Deprivation

1968
Studies of brain aminotransferase and psychotropic agents. I. Interaction of B-B'-iminodipropionitrile and rat brain aromatic aminotransferases.
    Biochemical pharmacology, 1969, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Aminopropionitrile; Animals; Brain; Brain Chemistry; Chromatography; Chromatography, Gel; Female; Kinetics; Nitriles; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyrosine

1969
Activity of aromatic aminotransferases in rat brain.
    Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:4

    Topics: 5-Hydroxytryptophan; Age Factors; Amino Acids; Animals; Brain; Dihydroxyphenylalanine; Fetus; Histidine; Humans; Infant, Newborn; Methods; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine

1968
Correlation between behavioral and biochemical effects of p-chlorophenylalanine in mice and rats.
    International journal of neuropharmacology, 1969, Volume: 8, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Catecholamines; Dopamine; Male; Mice; Motor Activity; Norepinephrine; Phenylalanine; Rats; Serotonin; Serotonin Antagonists; Species Specificity

1969
Effects of brain serotonin manipulations on multiple schedule performance in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 180, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Male; Phenylalanine; Rats; Reinforcement Schedule; Serotonin; Serotonin Antagonists

1969
Shortening of hexobarbital sleeping time after p-chlorophenylalanine.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 180, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Disulfiram; Drug Antagonism; Hexobarbital; Male; Mice; Phenylalanine; Sleep

1969
Compulsive sexual activity induced by p-chlorophenylalanine in normal and pinealectomized male rats.
    Science (New York, N.Y.), 1969, Dec-12, Volume: 166, Issue:3911

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Chloramines; Compulsive Behavior; Humans; Male; Pargyline; Phenylalanine; Pineal Gland; Rats; Serotonin Antagonists; Sexual Behavior, Animal

1969
Tachyphylaxis and toxicity of 5HT in anaesthetized rats.
    Acta pharmacologica et toxicologica, 1969, Volume: 27, Issue:6

    Topics: 5-Hydroxytryptophan; Anesthesia; Animals; Creatinine; Imipramine; Injections, Intravenous; Injections, Subcutaneous; Male; Neostigmine; Nialamide; Nicotine; Pentobarbital; Phenelzine; Phenylalanine; Physostigmine; Rats; Reserpine; Sensory Receptor Cells; Serotonin; Serotonin Antagonists; Tachyphylaxis; Tetrabenazine; Tryptamines

1969
Effect of tetrahydro-beta-naphtylamine on body temperature in rats.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 182, Issue:2

    Topics: 5-Hydroxytryptophan; Alkaloids; Amines; Animals; Body Temperature; Indoles; Naphthalenes; Nialamide; Norepinephrine; Phenylalanine; Quinolizines; Rats; Thiocarbamates

1969
The effect of parachlorophenylalanine on social interaction of male rats.
    British journal of pharmacology, 1970, Volume: 38, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Atropine; Behavior, Animal; Grooming; Hair; Male; Phenylalanine; Rats; Sexual Behavior, Animal

1970
Possible mechanism of action of morphine on brain.
    Nature, 1970, Mar-21, Volume: 225, Issue:5238

    Topics: 5-Hydroxytryptophan; Animals; Brain; Depression, Chemical; Drug Tolerance; Iproniazid; Methyltyrosines; Morphine; Motor Activity; Norepinephrine; Phenylalanine; Rats; Serotonin

1970
Essential role of testosterone in the sexual stimulation induced by p-chlorophenylalanine in male animals.
    Nature, 1970, Aug-08, Volume: 227, Issue:5258

    Topics: 5-Hydroxytryptophan; Animals; Brain; Castration; Compulsive Behavior; Dopamine; Drug Synergism; Humans; Male; Norepinephrine; Phenylalanine; Rats; Serotonin; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone

1970
DL-[2-14C]p-chlorophenylalanine as an inhibitor of tryptophan 5-hydroxylase.
    Journal of neurochemistry, 1970, Volume: 17, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Paper; Dialysis; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Pyruvates; Rats; Spectrophotometry; Tryptophan; Tyrosine

1970
P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin.
    The Journal of pharmacology and experimental therapeutics, 1970, Volume: 175, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorine; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Phenylalanine; Probenecid; Quinolizines; Rats; Reserpine; Serotonin; Tritium; Tryptophan

1970
The effect of parachlorophenylalanine on the behaviour of cats.
    British journal of pharmacology, 1970, Volume: 40, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cats; Estrus; Female; Male; Phenylalanine; Pregnancy; Sex Factors; Sexual Behavior, Animal; Skin; Sleep; Sleep Deprivation

1970
Effect of drugs on excitatory and inhibitory potentials in Helix aspersa.
    Experientia, 1971, Mar-15, Volume: 27, Issue:3

    Topics: 5-Hydroxytryptophan; Acetylcholine; Action Potentials; Animals; Brain; Cell Membrane; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Hemicholinium 3; In Vitro Techniques; Membrane Potentials; Morpholines; Phenethylamines; Phenylalanine; Reserpine; Serotonin; Snails; Synapses; Synaptic Membranes

1971
The role of 5-hydroxytryptamine in the behaviour of cats.
    The Journal of physiology, 1970, Volume: 210, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Cats; Female; Male; Phenylalanine; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal

1970
Effect of growth conditions on serotonin content of Tetrahymena pyriformis.
    The Journal of protozoology, 1970, Volume: 17, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Cell Count; Culture Media; Desipramine; Germ-Free Life; Phenylalanine; Reserpine; Serotonin; Tetrahymena; Time Factors; Tryptophan

1970
Microperfusion studies on renal tubular transport of tryptophan derivatives in rats.
    The American journal of physiology, 1971, Volume: 221, Issue:2

    Topics: 5-Hydroxytryptophan; Absorption; Animals; Azides; Biological Transport; Depression, Chemical; Dinitrophenols; Kidney Tubules; Kinetics; Perfusion; Phenylalanine; Rats; Stereoisomerism; Tritium; Tryptophan

1971
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
    Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:3

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines

1983
Impaired permeability of the blood-cerebrospinal fluid barrier in hyperphenylalaninaemia.
    Neuropediatrics, 1982, Volume: 13, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain Chemistry; Cattle; Choroid Plexus; Humans; In Vitro Techniques; Permeability; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan

1982
Tetrahydrobiopterin deficiency and an international database of patients.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biomarkers; Biopterins; Carbidopa; Child; Dihydropteridine Reductase; GTP Cyclohydrolase; Humans; Hydro-Lyases; Information Systems; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pterins; Registries

1993
[Progressive convulsive encephalopathy: considering a abnormality of biopterin metabolism].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1999, Volume: 6, Issue:7

    Topics: 5-Hydroxytryptophan; Algeria; Anticonvulsants; Biopterins; Brain; Child, Preschool; Consanguinity; Developmental Disabilities; Diet Therapy; Epilepsy; France; Humans; Levodopa; Magnetic Resonance Imaging; Male; Neopterin; Phenylalanine; Phenylketonurias

1999
Treatment and outcome of Taiwanese patients with 6-pyruvoyltetrahydropterin synthase gene mutations.
    Journal of inherited metabolic disease, 2001, Volume: 24, Issue:8

    Topics: 5-Hydroxytryptophan; Base Sequence; Biopterins; DNA Mutational Analysis; Founder Effect; Humans; Infant, Newborn; Intelligence; Levodopa; Mutation; Neonatal Screening; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Taiwan; Treatment Outcome

2001
[Solubility behavior of four diastereomeric salts and two amino acids in near-critical CO2].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2002, Volume: 37, Issue:5

    Topics: 5-Hydroxytryptophan; Ephedrine; Phenylalanine; Pressure; Solubility; Stereoisomerism; Tartrates; Temperature

2002
EFFECT OF RESERPINE ON AMINO ACIDS IN BRAIN.
    Archives internationales de pharmacodynamie et de therapie, 1963, Nov-01, Volume: 146

    Topics: 5-Hydroxytryptophan; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Glutamates; Histidine; Hydroxyproline; Nitrogen; Pharmacology; Phenylalanine; Proline; Proteins; Rats; Research; Reserpine; Tryptophan; Tyrosine

1963
MECHANISMS FOR THE DECREASE OF BRAIN SEROTONIN.
    Nature, 1963, Nov-09, Volume: 200

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Blood Chemical Analysis; Brain; Carboxy-Lyases; Dietary Proteins; Guinea Pigs; Indoles; Monoamine Oxidase; Phenylalanine; Phenylketonurias; Proteins; Pyridoxal Phosphate; Research; Serotonin

1963
TRANSAMINATION OF AROMATIC AMINO ACIDS IN RAT BRAIN.
    Journal of neurochemistry, 1964, Volume: 11

    Topics: 5-Hydroxytryptophan; Amino Acids, Aromatic; Brain; Chromatography; Dihydroxyphenylalanine; Keto Acids; Ketoglutaric Acids; Phenylalanine; Phenylpyruvic Acids; Rats; Research; Tissue Extracts; Transaminases; Tryptophan; Tyrosine

1964
PREVENTION OF A MENTAL DEFECT OF PHENYLKETONURIA WITH SEROTONIN CONGENERS SUCH AS MELATONIN OR HYDROXYTRYPTOPHAN.
    Science (New York, N.Y.), 1964, Jun-26, Volume: 144, Issue:3626

    Topics: 5-Hydroxytryptophan; Animals; Biomedical Research; Indoles; Learning; Melatonin; Mice; Pharmacology; Phenylalanine; Phenylketonurias; Research; Serotonin; Tyrosine

1964
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
    The Journal of biological chemistry, 1964, Volume: 239

    Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase

1964
NONTRANSPORT OF CERTAIN SUBSTITUTED AMINO ACIDS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: 5-Hydroxytryptophan; Absorption; Amino Acids; Animals; Biological Transport; Cricetinae; Histidine; Intestine, Small; Intestines; Pharmacology; Phenylalanine; Proteins; Research; Tryptophan

1964
INHIBITION BY PHENYLALANINE OF THE ENTRY OF 5-HYDROXY-TRYPTOPHAN-1-C14 INTO CEREBROSPINAL FLUID.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: 5-Hydroxytryptophan; Animals; Biological Transport; Blood; Blood-Brain Barrier; Brain; Carbon Isotopes; Dogs; Injections; Injections, Intravenous; Metabolism; Phenylalanine; Radiometry; Research; Tryptophan

1965
STUDIES ON INHIBITION OF BRAIN 5-HYDROXYTRYPTOPHAN DECARBOXYLASE BY PHENYLALANINE METABOLITES.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Antimetabolites; Aromatic-L-Amino-Acid Decarboxylases; Brain; Brain Chemistry; Carboxy-Lyases; Guinea Pigs; Pharmacology; Phenylalanine; Phenylketonurias; Research

1965
ON THE MECHANISM OF THE BRAIN SEROTONIN DEPLETION IN EXPERIMENTAL PHENYLKETONURIA.
    The Journal of biological chemistry, 1965, Volume: 240

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Ascorbic Acid; Blood; Brain; Brain Chemistry; Carboxy-Lyases; Cholinesterases; Corticosterone; Dopamine; Glutamates; Liver; Metabolism; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Phenylketonurias; Rats; Research; Serotonin; Transaminases; Tryptophan; Tyrosine

1965
UNIMPAIRED LEARNING ABILITY OF RATS MADE ARTIFICIALLY PHENYLKETONURIC DURING FETAL OR NEONATAL LIFE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain Chemistry; Diet; Discrimination Learning; Fetus; Phenylalanine; Phenylketonurias; Rats; Research; Serotonin; Toxicology

1965
Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.
    AJNR. American journal of neuroradiology, 2004, Volume: 25, Issue:9

    Topics: 5-Hydroxytryptophan; Axons; Biopterins; Brain Damage, Chronic; Cerebral Cortex; Child; Child, Preschool; Combined Modality Therapy; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence; Levodopa; Male; Neonatal Screening; Nerve Fibers, Myelinated; Phenylalanine; Phenylketonurias; Pregnancy

2004
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
    Annals of neurology, 2005, Volume: 58, Issue:1

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagnostic Errors; Dopamine Agents; Female; Humans; Levodopa; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures

2005
Long-term follow-up of Chinese patients who received delayed treatment for 6-pyruvoyl-tetrahydropterin synthase deficiency.
    Molecular genetics and metabolism, 2006, Volume: 87, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Asian People; Biopterins; Child; Child, Preschool; China; Female; Follow-Up Studies; Humans; Infant; Intellectual Disability; Levodopa; Male; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures; Time Factors

2006
[Study on tetrahydrobiopterin deficiency in Northern Chinese population].
    Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 2006, Volume: 23, Issue:3

    Topics: 5-Hydroxytryptophan; Asian People; Biopterins; Child, Preschool; China; Dihydropteridine Reductase; Humans; Infant; Levodopa; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases

2006
5-Hydroxytryptophan rescues serotonin response to stress in prefrontal cortex of hyperphenylalaninaemic mice.
    The international journal of neuropsychopharmacology, 2009, Volume: 12, Issue:8

    Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Diet, Reducing; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Mice; Microdialysis; Neuraminidase; Norepinephrine; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Serotonin; Time Factors; Tryptophan Hydroxylase

2009
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine

2014
Diagnosis, treatment and follow-up of patients with tetrahydrobiopterin deficiency in Shandong province, China.
    Brain & development, 2015, Volume: 37, Issue:6

    Topics: 5-Hydroxytryptophan; Biopterins; Child, Preschool; China; Follow-Up Studies; Genotype; Humans; Infant; Infant, Newborn; Intelligence Tests; Levodopa; Mutation; Neopterin; Phenylalanine; Phenylketonurias; Treatment Outcome

2015
Hydrophilic interaction chromatography combined with dispersive liquid-liquid microextraction as a preconcentration tool for the simultaneous determination of the panel of underivatized neurotransmitters in human urine samples.
    Journal of chromatography. A, 2016, Jan-29, Volume: 1431

    Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Acetonitriles; Chromatography, Liquid; Dopamine; Humans; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Liquid Phase Microextraction; Mass Spectrometry; Neurotransmitter Agents; Phenylalanine; Solvents; Urinalysis

2016
Metabolomic markers of antepartum depression and suicidal ideation.
    Journal of affective disorders, 2020, 02-01, Volume: 262

    Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Depression; Female; Humans; Logistic Models; Metabolomics; Odds Ratio; Patient Health Questionnaire; Peru; Phenylalanine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnant Women; Prospective Studies; Risk Factors; Suicidal Ideation; Triglycerides; Young Adult

2020