phenylalanine has been researched along with 5-hydroxytryptophan in 109 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 94 (86.24) | 18.7374 |
1990's | 2 (1.83) | 18.2507 |
2000's | 8 (7.34) | 29.6817 |
2010's | 4 (3.67) | 24.3611 |
2020's | 1 (0.92) | 2.80 |
Authors | Studies |
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Butler, IJ; Holtzman, NA; Kaufman, S; Koslow, SH; Krumholz, A | 1 |
Airaksinen, MM; MacDonald, EJ; Marvola, M; Turakka, H | 1 |
Sakurada, S | 1 |
Wirz-Justice, A | 1 |
Carlsson, A; Lindqvist, M | 2 |
Abroms, IF; Breslow, JL; Brewster, TG; Kaufman, S; Milstien, S; Moskowitz, MA | 1 |
Bautz, G; Dairman, W; Horst, WD; Marchelle, ME | 1 |
Faller, DV; Fernstrom, JD; Shabshelowitz, H | 1 |
Glassgold, JM; Hauser, DC; Levandowsky, M | 1 |
McKean, CM; Schafer, EW | 1 |
Biasetti, S; Bracco, G; Ferraris, S; Guardamagna, O; Niederwieser, A; Ponzone, A | 1 |
Spector, AA; Strom, DK; Yorek, MA | 1 |
Hayashi, T; Nakane, A; Naruse, H; Takesada, M; Yamazaki, K | 1 |
Pulmones, MT; Sansaricq, C; Snyderman, SE | 1 |
Blonder, J; Cohen, BE; Normand, M; Peled, I; Quint, J; Szeinberg, A | 1 |
Engelman, K; Fram, DH; Kupfer, DJ; Sjoerdsma, A; Snyder, F; Wyatt, RJ | 1 |
Dement, WC; Engelman, K; Sjoerdsma, A; Snyder, F; Wyatt, RJ; Zarcone, V | 1 |
Guano, G; Guilbaud, G; Menetrey, D | 1 |
Bert, J | 1 |
Korf, J; Postema, F; Venema, K | 1 |
Kido, R; Minatogawa, Y; Noguchi, T | 1 |
Kido, R; Nakamura, J; Noguchi, T | 1 |
Agarwal, MK | 1 |
Corgier, M; Pacheco, H; Tappaz, M | 1 |
Birkmayer, W | 1 |
Murali, DK; Radhakrishnan, AN | 1 |
von Studnitz, W; Waldenström, J | 1 |
Cheney, DL; Goldstein, A | 1 |
Campbell, BA; Fibiger, HC | 1 |
Geller, I; Hartmann, RJ | 1 |
Buguet, A; Froment, JL; Jones, B; Jouvet, M; Pujol, JF | 1 |
Ito, A; Schanberg, SM | 1 |
Azbekyan, SG; Lapin, IP; Oxenkrug, GF | 1 |
Hole, K | 1 |
Kilbey, MM; Nance, DM | 1 |
Dickens, G; Guroff, G; Letendre, CH | 1 |
Putkonen, PT | 1 |
Boggan, WO; Freedman, DX; Schlesinger, K | 1 |
Wyatt, RJ | 1 |
Boullin, DJ | 1 |
Brissaud, HE; Costil, J; Galli, J; Richardet, JM | 1 |
Prakh'e, IB | 1 |
Neuhoff, V; Osborne, NN | 1 |
Bensinger, RE; Klein, DC; Lovenberg, W; Weller, JL | 1 |
Loo, YH | 1 |
Behbehani, AW; Neuhoff, V; Quentin, CD; Schulte, FJ | 1 |
Davis, P; Juhl, R; Rosazza, JP | 1 |
Simpson, LL | 1 |
Aronson, RB; Cotzias, GC; Gellene, R; Papavasiliou, PS | 1 |
Grahame-Smith, DG | 1 |
Camba, R; Di Chiara, G; Spano, PF | 1 |
Hsia, DY | 1 |
Christenson, JG; Dairman, W; Udenfriend, S | 1 |
Görisch, H; Lingens, F | 1 |
Glick, D; Hosoda, S | 1 |
Van der Hoeven, T; Woolley, DW | 1 |
Koe, BK; Weissman, A | 1 |
De Ropp, RS; Furst, A | 1 |
Geller, E; Yuwiler, A | 1 |
Agathopoulos, A; Bafataki, M; Danelatou-Athanassiadou, C; Nicolopoulos, D | 1 |
Brown, RM; Lal, H | 1 |
Jouvet, M | 1 |
Gabay, S; Huang, KH | 1 |
Oja, SS | 1 |
Volicer, L | 1 |
Rosen, AJ | 1 |
Kadzielawa, K; Widy-Tyszkiewicz, E | 1 |
Brodie, BB; Gessa, GL; Tagliamonte, A; Tagliamonte, P | 1 |
Tammisto, T; Ylitalo, P | 1 |
Bruinvels, J; Kemper, GC | 1 |
Shillito, EE | 2 |
Eidelberg, E; Schwartz, AS | 1 |
Brodie, BB; Gessa, GL; Tagliamonte, A | 1 |
Gál, EM; Millard, SA; Roggeveen, AE | 1 |
Sanders-Bush, E; Sulser, F | 1 |
Hoyland, VJ; Shillito, EE; Vogt, M | 1 |
Kerkut, GA; Ralph, KL; Walker, RJ; Woodruff, GN | 1 |
Blum, JJ; Brizzi, G | 1 |
Chan, YL; Huang, KC | 1 |
Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS | 1 |
Hüther, G; Lane, JD; Neuhoff, V; Piel, N | 1 |
Blau, N; Dhondt, JL | 1 |
Dhondt, JL; Mikaeloff, Y; Pinton, F; Ponsot, G; Sevin, C | 1 |
Meyers, S | 1 |
Chiang, SC; Chien, YH; Chiu, YN; Chou, SP; Chu, SY; Huang, A; Hwu, WL; Lin, JM; Wang, TR | 1 |
Cai, YF; Chai, SH; Gao, LH; Liu, HL; Liu, LL; Wu, YT | 1 |
BOSE, BC; SAIFI, AQ; SHARMA, SK; VIJAYVARGIYA, R | 1 |
BRENCHLEY, Y; HSIA, DY; NISHIMURA, K | 1 |
FONNUM, F; HAAVALDSEN, R; TANGEN, O | 1 |
VANDERHOEVEN, T; WOOLLEY, DW | 1 |
JACOBY, GA; LADU, BN | 1 |
BRODY, KR; LUTTERS, BM; SPENCER, RP | 1 |
CARVER, MJ; COPENHAVER, JH; SCHAIN, RJ | 1 |
HSIA, DY; JUSTICE, P | 1 |
GELLER, E; SLATER, GG; YUWILER, A | 1 |
HANSEN, S; LING, GM; MACDOUGALL, L; PERRY, TL | 1 |
Chien, YH; Hwu, WL; Liu, HM; Peng, SS; Tseng, WY | 1 |
Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ | 1 |
Cheng, LY; Chiu, PC; Hsiao, KJ; Lee, NC; Liu, TT; Niu, DM | 1 |
Chang, M; Fu, GX; He, C; Hsiao, KJ; Li, XW; Liu, TT; Shen, M; Shen, S; Wang, L; Yu, WM; Zhao, SP | 1 |
Andolina, D; Cabib, S; Conversi, D; Latagliata, C; Mela, IL; Pascucci, T; Puglisi-Allegra, S; Ventura, R | 1 |
Boben-Bardutzky, D; Hafner, M; Ihan, A; Jukić, T; Rojc, B | 1 |
Budac, D; du Jardin, KG; Jensen, JB; Pehrson, AL; Sanchez, C; Smagin, G; Song, D | 1 |
Cao, Z; Han, B; Liu, Y; Zhu, W; Zou, H | 1 |
Bączek, T; Konieczna, L; Niedźwiecki, M; Roszkowska, A | 1 |
Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA | 1 |
5 review(s) available for phenylalanine and 5-hydroxytryptophan
Article | Year |
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Pharmacology of the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Bradykinin; Diarrhea; Drug Synergism; Humans; Kinins; Malignant Carcinoid Syndrome; Methysergide; Neurologic Manifestations; Phenylalanine; Prostaglandins; Serotonin; Serotonin Antagonists; Skin Manifestations | 1968 |
Monoamines and the regulation of vigilance and sleep.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Blood-Brain Barrier; Brain; Catecholamines; Depression, Chemical; Dihydroxyphenylalanine; Dopa Decarboxylase; Haplorhini; Humans; Muscle Tonus; Norepinephrine; Papio; Phenylalanine; Rats; Reserpine; Serotonin; Sleep Stages; Sleep, REM; Stimulation, Chemical; Tryptophan; Wakefulness | 1974 |
Progress report: the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydroxyindoleacetic Acid; Kallikreins; Liver Neoplasms; Malignant Carcinoid Syndrome; Methyldopa; Methysergide; Neoplasm Metastasis; Phenoxybenzamine; Phenylalanine; Serotonin | 1970 |
Biochemical factors in mental retardation.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Diet Therapy; Female; Guinea Pigs; Haplorhini; Humans; Infant; Intellectual Disability; Intelligence Tests; Male; Metabolism, Inborn Errors; Monoamine Oxidase; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan; Tyrosine | 1967 |
Use of neurotransmitter precursors for treatment of depression.
Topics: 5-Hydroxytryptophan; Depression; Humans; Phenylalanine; Tryptophan; Tyrosine | 2000 |
6 trial(s) available for phenylalanine and 5-hydroxytryptophan
Article | Year |
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[Metabolic changes in aromatic amino acids and monoamines in infantile autism and development of new treatment related to the finding].
Topics: 5-Hydroxytryptophan; Amino Acids; Autistic Disorder; Biogenic Monoamines; Biopterins; Carbon Isotopes; Child; Child, Preschool; Clinical Trials as Topic; Deuterium; Double-Blind Method; Humans; Levodopa; Phenylalanine; Tryptophan | 1989 |
Effects of L-tryptophan (a natural sedative) on human sleep.
Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aged; Female; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Phenylalanine; Placebos; Serotonin; Sex Factors; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM; Tryptophan | 1970 |
Effects of 5-hydroxytryptophan on the sleep of normal human subjects.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Animals; Brain; Cats; Electroencephalography; Electromyography; Electrooculography; Female; Humans; Hydroxyindoleacetic Acid; Male; Phenylalanine; Placebos; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Sleep, REM | 1971 |
The serotonin-catecholamine-dream bicycle: a clinical study.
Topics: 5-Hydroxytryptophan; Aged; Brain; Brain Chemistry; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dreams; Electroencephalography; Female; Fenclonine; Humans; Male; Mental Disorders; Middle Aged; Monoamine Oxidase Inhibitors; Phenylalanine; Serotonin; Sleep; Sleep, REM; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 1972 |
Parkinsonism and DOPA.
Topics: 5-Hydroxytryptophan; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Humans; Male; Manganese Poisoning; Mining; Occupational Diseases; Parkinson Disease; Phenylacetates; Phenylalanine; Placebos | 1968 |
The use of a food supplementation with D-phenylalanine, L-glutamine and L-5-hydroxytriptophan in the alleviation of alcohol withdrawal symptoms.
Topics: 5-Hydroxytryptophan; Alcoholism; Bilirubin; CD4-Positive T-Lymphocytes; Dietary Supplements; Double-Blind Method; Glutamine; Humans; Hydrocortisone; Phenylalanine; Prospective Studies; Substance Withdrawal Syndrome | 2011 |
98 other study(ies) available for phenylalanine and 5-hydroxytryptophan
Article | Year |
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A disorder of biogenic amines in dihydropteridine reductase deficiency.
Topics: 5-Hydroxytryptophan; Biogenic Amines; Brain; Child, Preschool; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Levodopa; Liver; Male; Neurotransmitter Agents; Phenylalanine; Phenylketonurias; Vanilmandelic Acid | 1978 |
Protective effect of tryptophan and 5-hydroxytryptophan on experimental phenylketonuria induced with phenylalanine+ p-cholorophenylalanine in rats.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Body Weight; Brain; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Motor Activity; Norepinephrine; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan | 1975 |
[Effects of beta-phenylethylamine derivatives on the central nervous system. (5) The effect of intracerebral administration of tyramine on head twitching in mice pre-treated with isocarboxazid].
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Brain; Drug Interactions; Fenclonine; Haloperidol; Head; Isocarboxazid; Male; Mice; Movement; Phenothiazines; Phenylalanine; Tyramine; Tyrosine | 1975 |
Theoretical and therapeutic potential of indolamine precursors in affective disorders.
Topics: 5-Hydroxytryptophan; Amino Acids; Bipolar Disorder; Depression; Emotions; Female; Humans; Levodopa; Male; Phenylalanine; Serotonin; Sex Factors; Tryptophan; Tyrosine | 1977 |
Dependence of 5-HT and catecholamine synthesis on concentrations of precursor amino-acids in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Catecholamines; Dihydroxyphenylalanine; Haloperidol; Isoleucine; Kinetics; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine | 1978 |
Dihydropteridine reductase deficiency associated with severe neurologic disease and mild hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Ascorbic Acid; Consanguinity; Dopamine; Humans; Infant; Levodopa; Liver; Male; NADH, NADPH Oxidoreductases; Nervous System Diseases; Phenylalanine; Phenylalanine Hydroxylase; Phenylketonurias; Serotonin | 1979 |
The proportionate loss of L-3,4-dihydroxyphenylalanine and L-5-hydroxttryptophan decarboxylating activity in rat central nervous system following intracisternal administration of 5, 6-dihydroxytryptamine or 6-hydroxydopamine.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carboxy-Lyases; Cerebral Cortex; Hydroxydopamines; Norepinephrine; Phenylalanine; Rats; Serotonin; Spinal Cord | 1975 |
Acute reduction of brain serotonin and 5-HIAA following food consumption: correlation with the ratio of serum tryptophan to the sum of competing amino acids.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Diet; Hydroxyindoleacetic Acid; Insulin; Isoleucine; Leucine; Male; Phenylalanine; Rats; Serotonin; Tryptophan; Tyrosine; Valine | 1975 |
Ultrasensitive chemosensory responses by a protozoan to epinephrine and other neurochemicals.
Topics: 5-Hydroxytryptophan; Animals; Betaine; Carbachol; Chemoreceptor Cells; Chemotaxis; Choline; Dose-Response Relationship, Drug; Epinephrine; Eukaryota; Glutamates; Glycine; Norepinephrine; Phenylalanine; Putrescine; Serotonin; Taurine; Tryptophan | 1975 |
Evidence that monoamines influence human evoked potentials.
Topics: 5-Hydroxytryptophan; Adolescent; Biogenic Amines; Dihydroxyphenylalanine; Evoked Potentials; Female; Humans; Male; Phenylalanine; Phenylketonurias; Reaction Time; Tyrosine; Visual Cortex; Visual Perception | 1975 |
Neurotransmitter therapy and diet in malignant phenylketonuria.
Topics: 5-Hydroxytryptophan; Carbidopa; Combined Modality Therapy; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Infant; Infant, Newborn; Levodopa; Phenylalanine; Phenylketonurias | 1987 |
Synthesis and high affinity uptake of serotonin and dopamine by human Y79 retinoblastoma cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Biological Transport; Cell Line; Dihydroxyphenylalanine; Dopamine; Eye Neoplasms; Humans; Hydroxyindoleacetic Acid; Kinetics; Norepinephrine; Phenylalanine; Retinoblastoma; Serotonin; Tryptophan; Tyrosine | 1987 |
Successful long term therapy of biopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Dihydropteridine Reductase; Female; Humans; Infant, Newborn; Levodopa; Liver; Neopterin; Phenylalanine; Phenylalanine Hydroxylase | 1987 |
Malignant phenylketonuria due to defective synthesis of dihydrobiopterin.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Drug Combinations; Female; Humans; Infant, Newborn; Levodopa; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines; Tyrosine | 1985 |
[Cerebral monoamines and evoked activity in the centrum medianum of the thalamus and in the primary somatic cortical area].
Topics: 5-Hydroxytryptophan; Amines; Amphetamine; Animals; Arousal; Brain Chemistry; Cats; Cerebral Cortex; Drug Synergism; Electric Stimulation; Evoked Potentials; Injections, Intraperitoneal; Methyldopa; Nialamide; Phenylalanine; Reserpine; Sleep Stages; Thalamus | 1971 |
[Effect of p-chlorophenylalanine on sleep in the baboon Papio papio].
Topics: 5-Hydroxytryptophan; Animals; Brain; Fenclonine; Haplorhini; Papio; Phenylalanine; Serotonin; Sleep; Sleep Stages | 1972 |
Decarboxylation of exogenous L-5-hydroxytryptophan after destruction of the cerebral raphe system.
Topics: 5-Hydroxytryptophan; Animals; Autoanalysis; Brain; Carboxy-Lyases; Cerebral Cortex; Histocytochemistry; Hydrazines; Hydroxyindoleacetic Acid; Male; Methyldopa; Phenylalanine; Rats; Serotonin; Staining and Labeling; Stereotaxic Techniques; Time Factors | 1974 |
Aromatic amino acid transaminases in rat brain.
Topics: 5-Hydroxytryptophan; Ammonium Sulfate; Animals; Brain; Chemical Precipitation; Chromatography, DEAE-Cellulose; Dihydroxyphenylalanine; Ketoglutaric Acids; Kynurenine; Male; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine Transaminase | 1973 |
Aromatic amino acid transaminase in rat intestine.
Topics: 5-Hydroxytryptophan; Animals; Chemical Phenomena; Chemistry, Physical; Chromatography, DEAE-Cellulose; Chromatography, Gel; Intestine, Small; Ketoglutaric Acids; Kinetics; Kynurenine; Male; Oxaloacetates; Phenylalanine; Pyruvates; Rats; Transaminases; Tryptophan; Tyrosine Transaminase | 1973 |
Interference by tryptophan analogues of an in vitro assay for liver tyrosine transaminase activity.
Topics: 5-Hydroxytryptophan; Animals; Colorimetry; Dihydroxyphenylalanine; Enzyme Activation; Kinetics; Leucine; Liver; Mice; Phenylalanine; Serotonin; Structure-Activity Relationship; Tryptophan; Tyrosine Transaminase | 1974 |
[Partial purification and study of different properties of 5-hydroxy-tryptophan decarboxylase from rat brain].
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbon Dioxide; Carbon Isotopes; Carboxy-Lyases; Chromatography, DEAE-Cellulose; Dopa Decarboxylase; Hydrogen-Ion Concentration; Hydroxylation; Kinetics; Male; Methods; Phenylalanine; Pyridoxal Phosphate; Rats; Ultracentrifugation | 1973 |
[Experimental findings and new aspects in extrapyramidal diseases].
Topics: 5-Hydroxytryptophan; Blood Pressure; Body Temperature Regulation; Chorea; Dihydroxyphenylalanine; Dopamine; Humans; Monoamine Oxidase Inhibitors; Movement Disorders; Norepinephrine; Parkinson Disease; Perphenazine; Phenylalanine; Reserpine; Serotonin; Tyrosine | 1966 |
Purification and properties of 5-hydroxytryptophan decarboxylase from monkey small intestine.
Topics: 5-Hydroxytryptophan; Amines; Animals; Aspartic Acid; Benzoates; Carboxy-Lyases; Edetic Acid; Glutamates; Glutathione; Haplorhini; Histidine; Intestine, Small; Keto Acids; Kinetics; Male; Mercaptoethanol; Metals; Phenylalanine; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1970 |
[Pharmacological and therapeutic studies (p-chlorphenylalanin) on carcinoid syndrome in 11 cases].
Topics: 5-Hydroxytryptophan; Aged; Blood Pressure; Bradykinin; Epinephrine; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Isoproterenol; Male; Malignant Carcinoid Syndrome; Metaraminol; Middle Aged; Mixed Function Oxygenases; Norepinephrine; Phentolamine; Phenylalanine; Serotonin; Tryptophan; Tyramine | 1971 |
The effect of p-chlorophenylalanine on opiate-induced running, analgesia, tolerance and physical dependence in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Behavior, Animal; Brain Chemistry; Drug Tolerance; Fenclonine; Humans; Levorphanol; Male; Morphine Dependence; Phenylalanine; Rats; Serotonin; Tritium | 1971 |
The effect of para-chlorophenylalanine on spontaneous locomotor activity in the rat.
Topics: 5-Hydroxytryptophan; Adaptation, Physiological; Animals; Behavior, Animal; Environment; Fenclonine; Locomotion; Phenylalanine | 1971 |
P-Chlorophenylalanine effects on a conditioned emotional response in rats.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Conditioning, Operant; Conditioning, Psychological; Electroshock; Fear; Fenclonine; Humans; Hunger; Male; Phenylalanine; Rats; Reward; Sound | 1971 |
The central metabolism of serotonin in the cat during insomnia. A neurophysiological and biochemical study after administration of P-chlorophenylalanine or destruction of the Raphé system.
Topics: 5-Hydroxytryptophan; Animals; Cats; Central Nervous System; Cerebral Cortex; Electroencephalography; Female; Fenclonine; Humans; Hydroxyindoleacetic Acid; Male; Phenylalanine; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Tritium | 1971 |
Central nervous system mechanisms responsible for blood pressure elevation induced by p-chlorophenylalanine.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Brain Chemistry; Central Nervous System; Drug Interactions; Esters; Fenclonine; Histological Techniques; Injections; Male; Norepinephrine; Phentolamine; Phenylalanine; Propranolol; Rats; Rats, Inbred Strains; Serotonin; Spinal Cord; Stereotaxic Techniques | 1972 |
Involvement of brain serotonin in the stimulant action of amphetamine and of cholinolytics.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Atropine; Benactyzine; Brain; Brain Chemistry; Drug Antagonism; Drug Synergism; Female; Fenclonine; Locomotion; Lysergic Acid Diethylamide; Male; Methylcellulose; Methysergide; Mice; Motor Activity; Norepinephrine; Phenylalanine; Receptors, Drug; Serotonin; Serotonin Antagonists; Stimulation, Chemical | 1972 |
Reduced 5-hydroxyindole synthesis reduces postnatal brain growth in rats.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Body Weight; Brain; Brain Chemistry; Drug Interactions; Female; Fenclonine; Hydroxylation; Indoles; Male; Nerve Tissue Proteins; Organ Size; Phenylalanine; Postpartum Period; Pregnancy; Rats; Rats, Inbred Strains; Serotonin; Time Factors | 1972 |
Self-selection of 5-hydroxytryptophan in dl-para-chlorophenylalanine treated rats.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain Chemistry; Drinking Behavior; Fenclonine; Food Preferences; Male; Phenylalanine; Rats; Serotonin; Taste; Water | 1972 |
The effect of L-tryptophan and some psychotropic drugs on the formation of 5-hydroxytryptophan in the mouse brain in vivo.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Benzyl Compounds; Brain; Carboxy-Lyases; Dimethylamines; Dose-Response Relationship, Drug; Feedback; Female; Fenclonine; Hydrazines; Hydroxyindoleacetic Acid; Lysergic Acid Diethylamide; Mice; Nialamide; Phenylalanine; Reserpine; Sensory Receptor Cells; Serine; Serotonin; Tryptamines; Tryptophan; Tryptophan Hydroxylase; Tyrosine | 1972 |
The tryptophan hydroxylase of Chromobacterium violaceum.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Cell Division; Chromatography, DEAE-Cellulose; Chromatography, Paper; Chromobacterium; Enzyme Induction; Fenclonine; Hydrogen-Ion Concentration; Kinetics; Mixed Function Oxygenases; Oxidation-Reduction; Phenylalanine; Pteridines; Spectrometry, Fluorescence; Sulfhydryl Reagents; Time Factors; Tryptophan; Tryptophan Hydroxylase | 1974 |
Genetics of audiogenic seizures. 3. Time response relationships between drug administration and seizure susceptibility.
Topics: 5-Hydroxytryptophan; Age Factors; Animals; Brain; Brain Chemistry; Female; Hydrazines; Iproniazid; Male; Methyltyrosines; Mice; Norepinephrine; Phenylalanine; Reserpine; Seizures; Serotonin; Sound; Time Factors | 1970 |
Platelet transaminase.
Topics: 5-Hydroxytryptophan; Acetates; Amination; Amino Acids; Aminobutyrates; Aspartic Acid; Blood Platelets; Carbon Isotopes; Glutamates; Glycolates; Humans; Hydroxylamines; Kinetics; Leucine; Phenylalanine; Transaminases; Tyrosine | 1972 |
[Urinary excretion of 5-hydroxyindoleacetic acid. II. In children with phenylketonuria, effects of 5-hydroxytryptophan].
Topics: 5-Hydroxytryptophan; Administration, Oral; Child, Preschool; Female; Humans; Hydroxyindoleacetic Acid; Infant; Injections, Intravenous; Intestinal Absorption; Male; Phenylalanine; Phenylketonurias | 1973 |
[Effect of agents, changing the monoamine level, on audiogenic epileptic seizures in rats].
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Brain; Depression, Chemical; Dihydroxyphenylalanine; Female; Male; Methyltyrosines; Methysergide; Nialamide; Norepinephrine; Phenylalanine; Rats; Reserpine; Seizures; Serotonin; Stimulation, Chemical | 1973 |
In vitro experiments on the metabolism, accumulation and release of 5-HT in the nervous system of the snail Helix pomatia.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Biological Transport, Active; Calcium; Carbon Radioisotopes; Chromatography, Thin Layer; Desipramine; Electric Stimulation; Ganglia; Hydroxyindoleacetic Acid; Imipramine; In Vitro Techniques; Isotope Labeling; Magnesium; Nerve Tissue; Ouabain; Phenylalanine; Serotonin; Snails; Sorbitol; Structure-Activity Relationship; Temperature; Time Factors; Tritium; Tryptophan | 1974 |
Radiometric assay of total tryptophan hydroxylation by intact cultured pineal glands.
Topics: 5-Hydroxytryptophan; Animals; Chromatography, Ion Exchange; Cycloheximide; Evaluation Studies as Topic; Female; Isoproterenol; Kinetics; Male; Melatonin; Mescaline; Methods; Mixed Function Oxygenases; Organ Culture Techniques; Phenylalanine; Pineal Gland; Probenecid; Rats; Serotonin; Species Specificity; Time Factors; Tritium; Tryptophan; Tryptophan Hydroxylase | 1974 |
Serotonin deficiency in experimental hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Animals; Biphenyl Compounds; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dopa Decarboxylase; Female; Humans; Hydroxyindoleacetic Acid; Oxazoles; Pargyline; Phenethylamines; Phenylalanine; Phenylketonurias; Pregnancy; Pyridoxal; Pyridoxamine; Pyridoxine; Rats; Serotonin; Spectrometry, Fluorescence; Time Factors; Tritium | 1974 |
Microanalysis with 14-C-dansyl chloride of amino acids and amines in the cerebrospinal fluid of patients with phenylketonuria. II. Determination of 5-hydroxyindole derivatives after loading with L-phenylalanine.
Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Autoradiography; Carbon Radioisotopes; Child; Child, Preschool; Dansyl Compounds; Humans; Hydroxyindoleacetic Acid; Hydroxylation; Infant; Methods; Microchemistry; Phenylalanine; Phenylketonurias; Serotonin | 1974 |
Tryptophol formation by Zygosaccharomyces priorianus.
Topics: 5-Hydroxytryptophan; Acetaldehyde; Amino Alcohols; Chromatography, Thin Layer; Fermentation; Fluorometry; Indoleacetic Acids; Indoles; Magnetic Resonance Spectroscopy; Phenylalanine; Pyruvates; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Stereoisomerism; Tryptamines; Tryptophan; Tyrosine | 1973 |
The interaction between 5-hydroxytryptamine and botulinum toxin type A.
Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Antitoxins; Botulism; Chlorine; Clostridium botulinum; Diaphragm; Female; Hydroxyindoleacetic Acid; In Vitro Techniques; Mice; Neuromuscular Junction; Norepinephrine; Pargyline; Phenylalanine; Phrenic Nerve; Rats; Serotonin; Toxins, Biological | 1968 |
Evidence for inhibition by brain serotonin of mouse killing behaviour in rats.
Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Brain; Humans; Injections, Intraperitoneal; Limbic System; Male; Methylation; Mice; Pargyline; Phenylalanine; Rats; Serotonin; Serotonin Antagonists; Tyrosine | 1971 |
Preparation and properties of a homogeneous aromatic L-amino acid decarboxylase from hog kidney.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbon Isotopes; Carboxy-Lyases; Chelating Agents; Chloromercuribenzoates; Chromatography, Ion Exchange; Copper; Dopa Decarboxylase; Electrophoresis, Disc; Ethylmaleimide; Female; Goats; Histidine; Hydrogen-Ion Concentration; Immunodiffusion; Iodoacetates; Kidney; Kinetics; Mercaptoethanol; Mercury; Methods; Molecular Weight; Phenylalanine; Pyridoxal Phosphate; Sulfhydryl Compounds; Swine; Tyrosine Decarboxylase; Ultracentrifugation; Zinc | 1970 |
3-D-eoxy-D-arabino-heptulosonate-7-phosphate synthase of Streptomyces aureofaciens Tü 24. II. Repression and inhibition by tryptophan and tryptophan analogues.
Topics: 5-Hydroxytryptophan; Aldehyde-Lyases; Allosteric Regulation; Enzyme Repression; Hydrogen-Ion Concentration; Phenylalanine; Phosphoenolpyruvate; Stereoisomerism; Streptomyces; Streptomyces aureofaciens; Tetroses; Tryptophan; Tyrosine | 1971 |
Studies in histochemistry. LXXIX. Properties of tryptophan hydroxylase from neoplastic murine mast cells.
Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Mast Cells; Mice; Mixed Function Oxygenases; Neoplasms; Phenylalanine; Serotonin; Tryptophan | 1966 |
Serotonin deficiency in infancy as a cause of a mental defect in experimental phenylketonuria.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Chlorpromazine; Electroshock; Female; Humans; In Vitro Techniques; Intellectual Disability; Learning; Male; Melatonin; Mice; Neurosecretion; Phenylalanine; Phenylketonurias; Phenylpyruvic Acids; Reserpine; Serotonin; Tryptamines; Tyrosine; Urine | 1965 |
p-Chlorophenylalanine: a specific depletor of brain serotonin.
Topics: 5-Hydroxytryptophan; Animals; Brain; Dogs; Hydroxyindoleacetic Acid; Liver; Mice; Mixed Function Oxygenases; Pargyline; Phenethylamines; Phenylalanine; Rats; Reserpine; Serotonin; Tetrabenazine | 1966 |
Effect of analogs of phenylalanine and tryptophan on kinetics of DOPA decarboxylase in rat brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Dihydroxyphenylalanine; Dopa Decarboxylase; Hydrogen-Ion Concentration; Kinetics; Male; Methyldopa; Phenylalanine; Pyridoxal Phosphate; Rats; Tryptophan; Tyrosine | 1966 |
Brain amine decrease in leucine-fed rats.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animal Feed; Animals; Ascorbic Acid; Blood-Brain Barrier; Body Weight; Brain; Brain Chemistry; Carboxy-Lyases; Corticosterone; Diet; Dopamine; Female; Glutamates; Leucine; Liver; Male; Mixed Function Oxygenases; Monoamine Oxidase; Norepinephrine; Organ Size; Oxygenases; Phenylalanine; Rats; Serotonin; Transaminases; Tryptophan; Tryptophan Oxygenase | 1967 |
Urinary exeretion of phenolic and indolic compounds, metacatecholamines, and VMA by full-term and premature infants.
Topics: 5-Hydroxytryptophan; Benzoates; Catecholamines; Cinnamates; Creatinine; Humans; Indoleacetic Acids; Infant, Newborn; Infant, Premature; Kynurenine; Lactates; Mandelic Acids; Phenylacetates; Phenylalanine; Phenylpyruvic Acids; Phthalic Acids; Propionates; Tryptophan; Tyrosine | 1968 |
A possible relationship between catecholamines and acute toxicity of desipramine.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Male; Methyldopa; Mice; Mortality; Phenylalanine; Reserpine | 1968 |
Insomnia and decrease of cerebral 5-hydroxytryptamine after destruction of the raphe system in the cat.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cats; Norepinephrine; Phenylalanine; Serotonin; Sleep; Sleep Deprivation | 1968 |
Studies of brain aminotransferase and psychotropic agents. I. Interaction of B-B'-iminodipropionitrile and rat brain aromatic aminotransferases.
Topics: 5-Hydroxytryptophan; Aminopropionitrile; Animals; Brain; Brain Chemistry; Chromatography; Chromatography, Gel; Female; Kinetics; Nitriles; Phenylalanine; Pyridoxal Phosphate; Rats; Transaminases; Tyrosine | 1969 |
Activity of aromatic aminotransferases in rat brain.
Topics: 5-Hydroxytryptophan; Age Factors; Amino Acids; Animals; Brain; Dihydroxyphenylalanine; Fetus; Histidine; Humans; Infant, Newborn; Methods; Phenylalanine; Rats; Transaminases; Tryptophan; Tyrosine | 1968 |
Correlation between behavioral and biochemical effects of p-chlorophenylalanine in mice and rats.
Topics: 5-Hydroxytryptophan; Animals; Brain; Catecholamines; Dopamine; Male; Mice; Motor Activity; Norepinephrine; Phenylalanine; Rats; Serotonin; Serotonin Antagonists; Species Specificity | 1969 |
Effects of brain serotonin manipulations on multiple schedule performance in the rat.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Male; Phenylalanine; Rats; Reinforcement Schedule; Serotonin; Serotonin Antagonists | 1969 |
Shortening of hexobarbital sleeping time after p-chlorophenylalanine.
Topics: 5-Hydroxytryptophan; Animals; Disulfiram; Drug Antagonism; Hexobarbital; Male; Mice; Phenylalanine; Sleep | 1969 |
Compulsive sexual activity induced by p-chlorophenylalanine in normal and pinealectomized male rats.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Chloramines; Compulsive Behavior; Humans; Male; Pargyline; Phenylalanine; Pineal Gland; Rats; Serotonin Antagonists; Sexual Behavior, Animal | 1969 |
Tachyphylaxis and toxicity of 5HT in anaesthetized rats.
Topics: 5-Hydroxytryptophan; Anesthesia; Animals; Creatinine; Imipramine; Injections, Intravenous; Injections, Subcutaneous; Male; Neostigmine; Nialamide; Nicotine; Pentobarbital; Phenelzine; Phenylalanine; Physostigmine; Rats; Reserpine; Sensory Receptor Cells; Serotonin; Serotonin Antagonists; Tachyphylaxis; Tetrabenazine; Tryptamines | 1969 |
Effect of tetrahydro-beta-naphtylamine on body temperature in rats.
Topics: 5-Hydroxytryptophan; Alkaloids; Amines; Animals; Body Temperature; Indoles; Naphthalenes; Nialamide; Norepinephrine; Phenylalanine; Quinolizines; Rats; Thiocarbamates | 1969 |
The effect of parachlorophenylalanine on social interaction of male rats.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Behavior, Animal; Grooming; Hair; Male; Phenylalanine; Rats; Sexual Behavior, Animal | 1970 |
Possible mechanism of action of morphine on brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Depression, Chemical; Drug Tolerance; Iproniazid; Methyltyrosines; Morphine; Motor Activity; Norepinephrine; Phenylalanine; Rats; Serotonin | 1970 |
Essential role of testosterone in the sexual stimulation induced by p-chlorophenylalanine in male animals.
Topics: 5-Hydroxytryptophan; Animals; Brain; Castration; Compulsive Behavior; Dopamine; Drug Synergism; Humans; Male; Norepinephrine; Phenylalanine; Rats; Serotonin; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone | 1970 |
DL-[2-14C]p-chlorophenylalanine as an inhibitor of tryptophan 5-hydroxylase.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbon Isotopes; Centrifugation, Density Gradient; Chromatography, Paper; Dialysis; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; Phenylalanine; Pyruvates; Rats; Spectrophotometry; Tryptophan; Tyrosine | 1970 |
P-chloroamphetamine: in vivo investigations on the mechanism of action of the selective depletion of cerebral serotonin.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorine; Hydroxyindoleacetic Acid; Male; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Norepinephrine; Pargyline; Phenylalanine; Probenecid; Quinolizines; Rats; Reserpine; Serotonin; Tritium; Tryptophan | 1970 |
The effect of parachlorophenylalanine on the behaviour of cats.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cats; Estrus; Female; Male; Phenylalanine; Pregnancy; Sex Factors; Sexual Behavior, Animal; Skin; Sleep; Sleep Deprivation | 1970 |
Effect of drugs on excitatory and inhibitory potentials in Helix aspersa.
Topics: 5-Hydroxytryptophan; Acetylcholine; Action Potentials; Animals; Brain; Cell Membrane; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Hemicholinium 3; In Vitro Techniques; Membrane Potentials; Morpholines; Phenethylamines; Phenylalanine; Reserpine; Serotonin; Snails; Synapses; Synaptic Membranes | 1971 |
The role of 5-hydroxytryptamine in the behaviour of cats.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Cats; Female; Male; Phenylalanine; Serotonin; Serotonin Antagonists; Sexual Behavior, Animal | 1970 |
Effect of growth conditions on serotonin content of Tetrahymena pyriformis.
Topics: 5-Hydroxytryptophan; Animals; Cell Count; Culture Media; Desipramine; Germ-Free Life; Phenylalanine; Reserpine; Serotonin; Tetrahymena; Time Factors; Tryptophan | 1970 |
Microperfusion studies on renal tubular transport of tryptophan derivatives in rats.
Topics: 5-Hydroxytryptophan; Absorption; Animals; Azides; Biological Transport; Depression, Chemical; Dinitrophenols; Kidney Tubules; Kinetics; Perfusion; Phenylalanine; Rats; Stereoisomerism; Tritium; Tryptophan | 1971 |
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines | 1983 |
Impaired permeability of the blood-cerebrospinal fluid barrier in hyperphenylalaninaemia.
Topics: 5-Hydroxytryptophan; Animals; Biological Transport, Active; Blood-Brain Barrier; Brain Chemistry; Cattle; Choroid Plexus; Humans; In Vitro Techniques; Permeability; Phenylalanine; Phenylketonurias; Rats; Serotonin; Tryptophan | 1982 |
Tetrahydrobiopterin deficiency and an international database of patients.
Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biomarkers; Biopterins; Carbidopa; Child; Dihydropteridine Reductase; GTP Cyclohydrolase; Humans; Hydro-Lyases; Information Systems; Levodopa; Metabolism, Inborn Errors; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Pterins; Registries | 1993 |
[Progressive convulsive encephalopathy: considering a abnormality of biopterin metabolism].
Topics: 5-Hydroxytryptophan; Algeria; Anticonvulsants; Biopterins; Brain; Child, Preschool; Consanguinity; Developmental Disabilities; Diet Therapy; Epilepsy; France; Humans; Levodopa; Magnetic Resonance Imaging; Male; Neopterin; Phenylalanine; Phenylketonurias | 1999 |
Treatment and outcome of Taiwanese patients with 6-pyruvoyltetrahydropterin synthase gene mutations.
Topics: 5-Hydroxytryptophan; Base Sequence; Biopterins; DNA Mutational Analysis; Founder Effect; Humans; Infant, Newborn; Intelligence; Levodopa; Mutation; Neonatal Screening; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Taiwan; Treatment Outcome | 2001 |
[Solubility behavior of four diastereomeric salts and two amino acids in near-critical CO2].
Topics: 5-Hydroxytryptophan; Ephedrine; Phenylalanine; Pressure; Solubility; Stereoisomerism; Tartrates; Temperature | 2002 |
EFFECT OF RESERPINE ON AMINO ACIDS IN BRAIN.
Topics: 5-Hydroxytryptophan; Amino Acids; Aminobutyrates; Aspartic Acid; Brain; Glutamates; Histidine; Hydroxyproline; Nitrogen; Pharmacology; Phenylalanine; Proline; Proteins; Rats; Research; Reserpine; Tryptophan; Tyrosine | 1963 |
MECHANISMS FOR THE DECREASE OF BRAIN SEROTONIN.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Blood Chemical Analysis; Brain; Carboxy-Lyases; Dietary Proteins; Guinea Pigs; Indoles; Monoamine Oxidase; Phenylalanine; Phenylketonurias; Proteins; Pyridoxal Phosphate; Research; Serotonin | 1963 |
TRANSAMINATION OF AROMATIC AMINO ACIDS IN RAT BRAIN.
Topics: 5-Hydroxytryptophan; Amino Acids, Aromatic; Brain; Chromatography; Dihydroxyphenylalanine; Keto Acids; Ketoglutaric Acids; Phenylalanine; Phenylpyruvic Acids; Rats; Research; Tissue Extracts; Transaminases; Tryptophan; Tyrosine | 1964 |
PREVENTION OF A MENTAL DEFECT OF PHENYLKETONURIA WITH SEROTONIN CONGENERS SUCH AS MELATONIN OR HYDROXYTRYPTOPHAN.
Topics: 5-Hydroxytryptophan; Animals; Biomedical Research; Indoles; Learning; Melatonin; Mice; Pharmacology; Phenylalanine; Phenylketonurias; Research; Serotonin; Tyrosine | 1964 |
STUDIES ON THE SPECIFICITY OF TYROSINE-ALPHA-KETOGLUTARATE TRANSAMINASE.
Topics: 5-Hydroxytryptophan; Alanine; Amphetamine; Benzoates; Butyrates; Catecholamines; Dihydroxyphenylalanine; Enzyme Inhibitors; Ephedrine; Indoleacetic Acids; Ketoglutaric Acids; Lactates; Liver; Mandelic Acids; Methyldopa; Normetanephrine; Pharmacology; Phenylacetates; Phenylalanine; Propionates; Rats; Research; Transaminases; Tryptophan; Tyramine; Tyrosine; Tyrosine Transaminase | 1964 |
NONTRANSPORT OF CERTAIN SUBSTITUTED AMINO ACIDS.
Topics: 5-Hydroxytryptophan; Absorption; Amino Acids; Animals; Biological Transport; Cricetinae; Histidine; Intestine, Small; Intestines; Pharmacology; Phenylalanine; Proteins; Research; Tryptophan | 1964 |
INHIBITION BY PHENYLALANINE OF THE ENTRY OF 5-HYDROXY-TRYPTOPHAN-1-C14 INTO CEREBROSPINAL FLUID.
Topics: 5-Hydroxytryptophan; Animals; Biological Transport; Blood; Blood-Brain Barrier; Brain; Carbon Isotopes; Dogs; Injections; Injections, Intravenous; Metabolism; Phenylalanine; Radiometry; Research; Tryptophan | 1965 |
STUDIES ON INHIBITION OF BRAIN 5-HYDROXYTRYPTOPHAN DECARBOXYLASE BY PHENYLALANINE METABOLITES.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Antimetabolites; Aromatic-L-Amino-Acid Decarboxylases; Brain; Brain Chemistry; Carboxy-Lyases; Guinea Pigs; Pharmacology; Phenylalanine; Phenylketonurias; Research | 1965 |
ON THE MECHANISM OF THE BRAIN SEROTONIN DEPLETION IN EXPERIMENTAL PHENYLKETONURIA.
Topics: 5-Hydroxytryptophan; Adrenal Glands; Ascorbic Acid; Blood; Brain; Brain Chemistry; Carboxy-Lyases; Cholinesterases; Corticosterone; Dopamine; Glutamates; Liver; Metabolism; Mixed Function Oxygenases; Norepinephrine; Phenylalanine; Phenylketonurias; Rats; Research; Serotonin; Transaminases; Tryptophan; Tyrosine | 1965 |
UNIMPAIRED LEARNING ABILITY OF RATS MADE ARTIFICIALLY PHENYLKETONURIC DURING FETAL OR NEONATAL LIFE.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain Chemistry; Diet; Discrimination Learning; Fetus; Phenylalanine; Phenylketonurias; Rats; Research; Serotonin; Toxicology | 1965 |
Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.
Topics: 5-Hydroxytryptophan; Axons; Biopterins; Brain Damage, Chronic; Cerebral Cortex; Child; Child, Preschool; Combined Modality Therapy; Corpus Callosum; Diffusion Magnetic Resonance Imaging; Dominance, Cerebral; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intelligence; Levodopa; Male; Neonatal Screening; Nerve Fibers, Myelinated; Phenylalanine; Phenylketonurias; Pregnancy | 2004 |
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagnostic Errors; Dopamine Agents; Female; Humans; Levodopa; Movement Disorders; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures | 2005 |
Long-term follow-up of Chinese patients who received delayed treatment for 6-pyruvoyl-tetrahydropterin synthase deficiency.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Asian People; Biopterins; Child; Child, Preschool; China; Female; Follow-Up Studies; Humans; Infant; Intellectual Disability; Levodopa; Male; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases; Seizures; Time Factors | 2006 |
[Study on tetrahydrobiopterin deficiency in Northern Chinese population].
Topics: 5-Hydroxytryptophan; Asian People; Biopterins; Child, Preschool; China; Dihydropteridine Reductase; Humans; Infant; Levodopa; Phenylalanine; Phenylketonurias; Phosphorus-Oxygen Lyases | 2006 |
5-Hydroxytryptophan rescues serotonin response to stress in prefrontal cortex of hyperphenylalaninaemic mice.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Diet, Reducing; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Mice; Microdialysis; Neuraminidase; Norepinephrine; Phenylalanine; Phenylketonurias; Prefrontal Cortex; Serotonin; Time Factors; Tryptophan Hydroxylase | 2009 |
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relationship, Drug; Duloxetine Hydrochloride; Exploratory Behavior; Female; Hippocampus; Maze Learning; Memory Disorders; Phenylalanine; Piperazines; Protein Binding; Rats; Rats, Long-Evans; Recognition, Psychology; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Thiophenes; Vortioxetine | 2014 |
Diagnosis, treatment and follow-up of patients with tetrahydrobiopterin deficiency in Shandong province, China.
Topics: 5-Hydroxytryptophan; Biopterins; Child, Preschool; China; Follow-Up Studies; Genotype; Humans; Infant; Infant, Newborn; Intelligence Tests; Levodopa; Mutation; Neopterin; Phenylalanine; Phenylketonurias; Treatment Outcome | 2015 |
Hydrophilic interaction chromatography combined with dispersive liquid-liquid microextraction as a preconcentration tool for the simultaneous determination of the panel of underivatized neurotransmitters in human urine samples.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Acetonitriles; Chromatography, Liquid; Dopamine; Humans; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Liquid Phase Microextraction; Mass Spectrometry; Neurotransmitter Agents; Phenylalanine; Solvents; Urinalysis | 2016 |
Metabolomic markers of antepartum depression and suicidal ideation.
Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Depression; Female; Humans; Logistic Models; Metabolomics; Odds Ratio; Patient Health Questionnaire; Peru; Phenylalanine; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnant Women; Prospective Studies; Risk Factors; Suicidal Ideation; Triglycerides; Young Adult | 2020 |