phenyl-n-tert-butylnitrone and d-alpha tocopherol

phenyl-n-tert-butylnitrone has been researched along with d-alpha tocopherol in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's10 (35.71)18.2507
2000's17 (60.71)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casara, P; Dorey, G; Lestage, P; Lockhart, B1
Bouajila, J; Bouskela, E; Costa, PR; Cyrino, FZ; de A Vilela, GV; Dias, AG; Kim, S; Nepveu, F1
Bracciotti, G; Falsini, S; Novelli, GP1
Furman, BL; McKechnie, K; Parratt, JR1
Bolli, R; Hartley, CJ; McCay, PB; Schleman, M; Sun, JZ; Tang, XL1
Burhop, K; Deby, C; Defraigne, JO; Detry, O; Franssen, C; Lamy, M; Meurisse, M; Philippart, C; Pincemail, J1
Arendash, GW; Crandall, BM; Socci, DJ1
Ferguson, E; Hogg, N; Kalyanaraman, B; Singh, RJ1
Campbell, M; Chen, SG; Del Bigio, MR; Peeling, J; Yan, HJ1
Blasig, IE; Haseloff, RF; Pissarek, M; Vrbjar, N; Zöllner, S1
Aksenov, M; Aksenova, M; Allen, K; Butterfield, DA; Carney, J; Hall, N; Hensley, K; Howard, B; Koppal, T; Subramaniam, R; Yatin, S1
Barja, G; Cadenas, S1
Floyd, RA1
Barclay, LR; Vinqvist, MR1
Fonnum, F; Lock, EA; Rustad, A; Sturgess, NC1
Dettbarn, WD; Gupta, RC; Milatovic, D; Zivin, M2
García, O; Massieu, L1
Dettbarn, WD; Gupta, RC; Milatovic, D3
Castranova, V; Gunther, MR; Kadiiska, MB; Kisin, ER; Kommineni, C; Mason, RP; Murray, AR; Shvedova, AA1
Keilhoff, G; Krug, M; Rauca, C; Wiswedel, I; Zerbe, R1
Blasiak, J; Czechowska, A; Gloc, E; Wozniak, K1
Iannone, A; Rota, C; Tomasi, A1
Ray, DE; Willis, CL1
Bailey, DM; Henry, RR; Jackson, SK; James, PE; Lawrenson, L; Mathieu-Costello, O; McCord, JM; McEneny, J; Richardson, RS; Young, IS1
Ancha, HR; Harty, RF; Kurella, RR; Lightfoot, S; McKimmey, CC1

Reviews

2 review(s) available for phenyl-n-tert-butylnitrone and d-alpha tocopherol

ArticleYear
Structural and functional changes in proteins induced by free radical-mediated oxidative stress and protective action of the antioxidants N-tert-butyl-alpha-phenylnitrone and vitamin E.
    Annals of the New York Academy of Sciences, 1998, Nov-20, Volume: 854

    Topics: Adult; Aging; Animals; Antioxidants; Brain; Cerebrovascular Disorders; Cyclic N-Oxides; DNA, Mitochondrial; Free Radicals; Humans; Mice; Mitochondria; Nitrogen Oxides; Oxidative Stress; Protein Conformation; Proteins; Reactive Oxygen Species; RNA, Messenger; Vitamin E

1998
Antioxidants, oxidative stress, and degenerative neurological disorders.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 222, Issue:3

    Topics: Alzheimer Disease; Animals; Antioxidants; Brain; Cyclic N-Oxides; Free Radicals; Humans; Mitogen-Activated Protein Kinases; Neurodegenerative Diseases; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Vitamin E

1999

Other Studies

26 other study(ies) available for phenyl-n-tert-butylnitrone and d-alpha tocopherol

ArticleYear
New quinolinic derivatives as centrally active antioxidants.
    Bioorganic & medicinal chemistry letters, 2000, May-01, Volume: 10, Issue:9

    Topics: Animals; Antioxidants; Cell Line; Electrons; Ethoxyquin; Hippocampus; Isoquinolines; Mice; Neurons; Neuroprotective Agents; Oxidants; Oxidative Stress; Quinolinic Acids; Structure-Activity Relationship; tert-Butylhydroperoxide; Vitamin E

2000
Alpha-phenyl-N-tert-butyl nitrone (PBN) derivatives: synthesis and protective action against microvascular damages induced by ischemia/reperfusion.
    Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10

    Topics: Animals; Capillaries; Chromatography, High Pressure Liquid; Cricetinae; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Indicators and Reagents; Male; Mesocricetus; Mouth Mucosa; Regional Blood Flow; Reperfusion Injury; Spectrophotometry, Ultraviolet; Structure-Activity Relationship

2007
Spin-trappers and vitamin E prolong endurance to muscle fatigue in mice.
    Free radical biology & medicine, 1990, Volume: 8, Issue:1

    Topics: Animals; Cyclic N-Oxides; Fatigue; Free Radicals; Male; Mice; Nitrogen Oxides; Physical Endurance; Pyridines; Spin Labels; Swimming; Vitamin E

1990
Modification by oxygen free radical scavengers of the metabolic and cardiovascular effects of endotoxin infusion in conscious rats.
    Circulatory shock, 1986, Volume: 19, Issue:4

    Topics: Allopurinol; Animals; Blood Glucose; Cardiovascular Physiological Phenomena; Cardiovascular System; Catalase; Cyclic N-Oxides; Endotoxins; Free Radicals; Glutathione; Lactates; Lactic Acid; Male; Nitrogen Oxides; Oxygen; Prostaglandins; Rats; Rats, Inbred Strains; Shock, Septic; Superoxide Dismutase; Vitamin E

1986
Inhibitory effect of a hydrophilic alpha-tocopherol analogue, MDL 74,405, on generation of free radicals in stunned myocardium in dogs.
    Free radical research, 1995, Volume: 22, Issue:4

    Topics: Animals; Blood Pressure; Body Temperature; Coronary Circulation; Cyclic N-Oxides; Dogs; Electron Spin Resonance Spectroscopy; Free Radicals; Heart Rate; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Nitrogen Oxides; Oxidative Stress; Time Factors; Vitamin E

1995
Diaspirin crosslinked hemoglobin (DCLHb): absence of increased free radical generation following administration in a rabbit model of renal ischemia and reperfusion.
    Free radical biology & medicine, 1995, Volume: 19, Issue:1

    Topics: Animals; Aspirin; Cyclic N-Oxides; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hemoglobins; Ischemia; Kidney; Kidney Cortex; Nitrogen Oxides; Rabbits; Reperfusion; Spin Labels; Vitamin E

1995
Chronic antioxidant treatment improves the cognitive performance of aged rats.
    Brain research, 1995, Sep-25, Volume: 693, Issue:1-2

    Topics: Aging; Animals; Antioxidants; Behavior, Animal; Cognition; Cyclic N-Oxides; Lipid Peroxidation; Male; Motor Activity; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spin Labels; Time Factors; Vitamin E

1995
The mechanism of apolipoprotein B-100 thiol depletion during oxidative modification of low-density lipoprotein.
    Archives of biochemistry and biophysics, 1997, May-15, Volume: 341, Issue:2

    Topics: Antioxidants; Apolipoprotein B-100; Apolipoproteins B; Copper; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Kinetics; Lipid Peroxidation; Lipoproteins, LDL; Nitrates; Nitrogen Oxides; Oxidation-Reduction; Pyridines; Spin Labels; Sulfhydryl Compounds; Sulfhydryl Reagents; Vitamin E

1997
Protective effects of free radical inhibitors in intracerebral hemorrhage in rat.
    Brain research, 1998, Jun-08, Volume: 795, Issue:1-2

    Topics: Animals; Ascorbic Acid; Behavior, Animal; Body Temperature; Cerebral Hemorrhage; Cyclic N-Oxides; Feeding Behavior; Free Radical Scavengers; Free Radicals; Magnetic Resonance Imaging; Male; Neurologic Examination; Neuroprotective Agents; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Thiourea; Vitamin E

1998
PBN spin trapping of free radicals in the reperfusion-injured heart. Limitations for pharmacological investigations.
    Molecular and cellular biochemistry, 1998, Volume: 186, Issue:1-2

    Topics: Animals; Antioxidants; Arrhythmias, Cardiac; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glycine; Heart; In Vitro Techniques; Kinetics; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Spin Labels; Sulfhydryl Compounds; Ventricular Function, Left; Verapamil; Vitamin E

1998
Resveratrol, melatonin, vitamin E, and PBN protect against renal oxidative DNA damage induced by the kidney carcinogen KBrO3.
    Free radical biology & medicine, 1999, Volume: 26, Issue:11-12

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Body Weight; Bromates; Carcinogens; Cyclic N-Oxides; DNA Damage; Kidney; Male; Melatonin; Nitrogen Oxides; Organ Size; Rats; Rats, Wistar; Resveratrol; Spin Labels; Stilbenes; Vitamin E

1999
Do spin traps also act as classical chain-breaking antioxidants? A quantitative kinetic study of phenyl tert-butylnitrone (PBN) in solution and in liposomes.
    Free radical biology & medicine, 2000, Apr-01, Volume: 28, Issue:7

    Topics: Antioxidants; Chromans; Cyclic N-Oxides; Free Radicals; Kinetics; Lipid Bilayers; Lipid Peroxidation; Liposomes; Nitriles; Nitrogen Oxides; Oxygen; Partial Pressure; Peroxides; Phospholipids; Solutions; Spin Labels; Spin Trapping; Vitamin E

2000
Neurotoxic effect of L-2-chloropropionic acid on primary cultures of rat cerebellar granule cells.
    Archives of toxicology, 2000, Volume: 74, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Cerebellum; Cyclic N-Oxides; Cytoplasmic Granules; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Hydrocarbons, Chlorinated; Neurons; Neurotoxins; Nitrogen Oxides; Propionates; Rats; Vitamin E

2000
Seizure-induced changes in energy metabolites and effects of N-tert-butyl-alpha-phenylnitrone (PNB) and vitamin E in rats.
    Pflugers Archiv : European journal of physiology, 2000, Volume: 440, Issue:5 Suppl

    Topics: Animals; Antioxidants; Brain; Cyclic N-Oxides; Energy Metabolism; Excitatory Amino Acid Agonists; Kainic Acid; Male; Nitrogen Oxides; Phosphates; Rats; Rats, Sprague-Dawley; Status Epilepticus; Tissue Distribution; Vitamin E

2000
Strategies for neuroprotection against L-trans-2,4-pyrrolidine dicarboxylate-induced neuronal damage during energy impairment in vitro.
    Journal of neuroscience research, 2001, May-15, Volume: 64, Issue:4

    Topics: Animals; Cell Survival; Cells, Cultured; Cerebellum; Coloring Agents; Convulsants; Cyclic N-Oxides; Dicarboxylic Acids; Energy Metabolism; Enzyme Inhibitors; Glutamic Acid; Mitochondria; Neurons; Neuroprotective Agents; Neurotransmitter Uptake Inhibitors; Nitro Compounds; Nitrogen Oxides; Propionates; Pyrrolidines; Rats; Rats, Wistar; Sodium Azide; Tetrazolium Salts; Thiazoles; Vitamin E

2001
Depletion of energy metabolites following acetylcholinesterase inhibitor-induced status epilepticus: protection by antioxidants.
    Neurotoxicology, 2001, Volume: 22, Issue:2

    Topics: Adenosine Triphosphate; Animals; Antioxidants; Brain Chemistry; Carbofuran; Cholinesterase Inhibitors; Citrulline; Cyclic N-Oxides; Energy Metabolism; Free Radical Scavengers; Male; Mitochondria; Nitric Oxide; Nitrogen Oxides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Status Epilepticus; Vitamin E

2001
Alterations in cytochrome c oxidase activity and energy metabolites in response to kainic acid-induced status epilepticus.
    Brain research, 2001, Aug-31, Volume: 912, Issue:1

    Topics: Adenosine Triphosphate; Amygdala; Animals; Antioxidants; Brain; Cerebral Cortex; Cyclic N-Oxides; Electron Transport Complex IV; Energy Metabolism; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Nerve Degeneration; Neurotoxins; Nitrogen Oxides; Oxidative Stress; Phosphocreatine; Rats; Reactive Oxygen Species; RNA, Messenger; Status Epilepticus; Vitamin E

2001
Nitric oxide modulates high-energy phosphates in brain regions of rats intoxicated with diisopropylphosphorofluoridate or carbofuran: prevention by N-tert-butyl-alpha-phenylnitrone or vitamin E.
    Archives of toxicology, 2001, Volume: 75, Issue:6

    Topics: Adenosine Triphosphate; Amygdala; Animals; Antioxidants; Brain; Carbofuran; Cerebral Cortex; Cholinesterase Inhibitors; Citrulline; Cyclic N-Oxides; Hippocampus; Insecticides; Isoflurophate; Male; Neuroprotective Agents; Nitric Oxide; Nitrogen Oxides; Phosphocreatine; Rats; Rats, Sprague-Dawley; Seizures; Time Factors; Vitamin E

2001
Antioxidant balance and free radical generation in vitamin e-deficient mice after dermal exposure to cumene hydroperoxide.
    Chemical research in toxicology, 2002, Volume: 15, Issue:11

    Topics: Administration, Cutaneous; Animals; Antioxidants; Ascorbic Acid; Benzene Derivatives; Biomarkers; Cyclic N-Oxides; Female; Free Radicals; Glutathione; Lipid Peroxidation; Mice; Mice, Inbred BALB C; Nitrogen Oxides; Oxidative Stress; Skin; Spin Labels; Spin Trapping; Sulfhydryl Compounds; Vitamin E; Vitamin E Deficiency

2002
Involvement of nitric oxide in kainic acid-induced excitotoxicity in rat brain.
    Brain research, 2002, Dec-13, Volume: 957, Issue:2

    Topics: Adenosine Triphosphate; Animals; Brain; Cell Death; Citrulline; Cyclic N-Oxides; Disease Models, Animal; Free Radical Scavengers; Kainic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Nitric Oxide; Nitrogen Oxides; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Status Epilepticus; Up-Regulation; Vitamin E

2002
The role of superoxide dismutase and alpha-tocopherol in the development of seizures and kindling induced by pentylenetetrazol - influence of the radical scavenger alpha-phenyl-N-tert-butyl nitrone.
    Brain research, 2004, May-29, Volume: 1009, Issue:1-2

    Topics: alpha-Tocopherol; Analysis of Variance; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Convulsants; Cyclic N-Oxides; Disease Models, Animal; Drug Administration Schedule; Gentisates; Hydroxybenzoates; Kindling, Neurologic; Male; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Oxides; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Superoxide Dismutase; Time Factors

2004
Genotoxicity of acrylamide in human lymphocytes.
    Chemico-biological interactions, 2004, Oct-15, Volume: 149, Issue:2-3

    Topics: Acrylamide; Adult; Apoptosis; Ascorbic Acid; Caspase 3; Caspases; Cell Survival; Comet Assay; Cyclic N-Oxides; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Electrophoresis, Gel, Pulsed-Field; Humans; Lymphocytes; Male; Mutagens; Nitrogen Oxides; Spin Trapping; Thymine DNA Glycosylase; Vitamin E

2004
Alpha-tocopherol amplifies benzoyl peroxide free radical decomposition in a chemical system.
    Free radical research, 2006, Volume: 40, Issue:6

    Topics: alpha-Tocopherol; Benzoyl Peroxide; Computer Simulation; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radicals; Molecular Structure; Nitrogen Oxides

2006
Antioxidants attenuate MK-801-induced cortical neurotoxicity in the rat.
    Neurotoxicology, 2007, Volume: 28, Issue:1

    Topics: Animals; Antioxidants; Cell Death; Cerebral Cortex; Cerebrovascular Circulation; Cyclic N-Oxides; Dimethyl Sulfoxide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Free Radical Scavengers; Neurons; Oxidative Stress; Pyrroles; Rats; Rats, Inbred F344; Vitamin E

2007
Electron paramagnetic spectroscopic evidence of exercise-induced free radical accumulation in human skeletal muscle.
    Free radical research, 2007, Volume: 41, Issue:2

    Topics: Adult; alpha-Tocopherol; Antioxidants; beta Carotene; Carotenoids; Coenzymes; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Exercise; Free Radical Scavengers; Free Radicals; Humans; Lipid Peroxidation; Lipid Peroxides; Lycopene; Male; Mitochondria, Muscle; Muscle Proteins; Muscle, Skeletal; Oxidative Stress; Spin Labels; Ubiquinone; Vitamin A

2007
Luminal antioxidants enhance the effects of mesalamine in the treatment of chemically induced colitis in rats.
    Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:10

    Topics: Animals; Antioxidants; Ascorbic Acid; Colitis; Cyclic N-Oxides; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Intestinal Mucosa; Male; Mesalamine; Rats; Rats, Sprague-Dawley; Trinitrobenzenesulfonic Acid; Vitamin E

2008